verapamil and felodipine

verapamil has been researched along with felodipine in 73 studies

Research

Studies (73)

TimeframeStudies, this research(%)All Research%
pre-199015 (20.55)18.7374
1990's31 (42.47)18.2507
2000's15 (20.55)29.6817
2010's12 (16.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dietel, M; Höllt, V; Kouba, M; Vogt, G1
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Evans, CA; Jolivette, LJ; Nagilla, R; Ward, KW1
Lombardo, F; Obach, RS; Waters, NJ1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Brouillette, WJ; Brown, GB; Zha, C1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Jacinto, SM; Jandhyala, BS1
Guido, S; Joseph, T1
Messing, M; Smith, TL; Smits, JF; Struyker-Boudier, HA; Van Essen, H1
Nordlander, M; Sjölander, M; Thorén, P1
Dong, H; Lu, YQ; Wang, Q; Yang, QQ; Yang, ZC1
Dupont, AG; Huyghens, L; Reynaert, H; Schoors, DF; Vanhaelst, L1
Björkman, JA; Ek, L; Gustafsson, D; Ljung, B; Nordlander, M1
Dalaker, K; Prydz, H1
Kjellstedt, A; Ljung, B; Orebäck, B1
Cubela, R; Debrevi, L; Jackson, B; Johnston, CI; Whitty, M1
Marwood, JF2
Alkadhi, KA; Hogan, YH; Jandhyala, BS; Sabouni, MH1
Eikenburg, DC; Jandhyala, BS; Lokhandwala, MF; Peter, EJ; Steenberg, ML1
Littler, WA; Smith, SA1
Barbieri, L; Camerini, F; Mestroni, L1
Lim, SL; May, PB; Sutter, MC1
Bush, LR; D'Alonzo, AJ; Evans, RM; Gaul, SL1
Bengtsson, B; Khan, AR; Weiber, R1
Haraldsson, B; Rippe, B; Zackrisson, U1
Bengtsson, B; Edgar, B; Raner, S; Rönn, O1
Schwartz, A; Tsai, LI; Wang, T1
Adegbile, IA; Cervenka, JH; Kailasam, MT; Kennedy, BP; O'Connor, DT; Parmer, RJ; Wu, RA; Ziegler, MG1
Hagiwara, S; Karaki, H; Mitsui, M1
Bülow, A; Johansson, B1
Dai, ZX; Xu, DZ; Yang, ZC; Yao, MH1
Boyd, IW1
Cambar, J; L'Azou, B; Lakhdar, B1
Agrotis, A; Bobik, A; Little, PJ; Saltis, J1
Ezra, D; Peleg, E; Rosenthal, T; Shamiss, A1
Block, LH; Eickelberg, O; Erne, P; Kohler, E; Roth, M1
Kikuchi, K; Sugawara, H; Tobise, K1
Dumitrescu, A; Haga, Y; Sjöquist, PO; Stain-Malmgren, R; Zhang, Y1
Marwood, JF; Okoro, EO1
Apicella, C; Bonaduce, D; Cavallaro, V; Ianniciello, A; Marciano, F; Petretta, M1
Altschuld, RA; Hensley, J; Hoepf, TM; Hohl, CM; McCune, SA; Park, S; Radin, MJ1
Andrade, C; Candade, VS; Faruqi, S; Kamath, S; Naga Rani, MA; Venkataraman, BV1
White, CM1
Bossi, M; Tiberti, G1
Gong, QY; Shi, NC; Yang, ZC; Zheng, P1
Akkaya, V; Ark, E; Ecder, T; Sever, MS; Türk, S; Türkmen, A; Yildiz, A1
Bakris, GL; Bidani, AK; Griffin, KA; Picken, MM1
Bonaduce, D; Canonico, V; Madrid, A; Marciano, F; Mickiewicz, M; Petretta, M; Signorini, A; Spinelli, L; Vetrano, A1
Hoepf, T; McCune, SA; Park, SC; Radin, MJ1
Arvola, P; Nordback, I; Sand, J1
Sahney, S1
Grimm, E; Herrmann, D; Kintscher, U; Scholze, J; Unger, T1
Minarovic, I; Zahradník, I; Zahradníková, A1
Baron, JA; Bøtker, HE; Jensen, LO; Johansen, MB; Kaltoft, A; Maeng, M; Robertson, DJ; Schmidt, M; Sørensen, HT; Tilsted, HH1
Naveen Babu, K; Ravindra Babu, P; Sridhar, V; Surya Sandeep, M1

Reviews

5 review(s) available for verapamil and felodipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Antihypertensive agents--the race for third place.
    Journal of clinical and hospital pharmacy, 1985, Volume: 10, Issue:2

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Captopril; Diazoxide; Felodipine; Humans; Hydralazine; Indoramin; Labetalol; Minoxidil; Nicardipine; Nifedipine; Vasodilator Agents; Verapamil

1985
[Calcium antagonists in congestive heart failure].
    Giornale italiano di cardiologia, 1988, Volume: 18, Issue:11

    Topics: Calcium Channel Blockers; Cardiomyopathy, Dilated; Diltiazem; Felodipine; Heart Failure; Hemodynamics; Humans; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Verapamil

1988
Calcium channel blockers in left ventricular dysfunction or congestive heart failure.
    Connecticut medicine, 1997, Volume: 61, Issue:10

    Topics: Amlodipine; Calcium Channel Blockers; Clinical Trials as Topic; Diltiazem; Felodipine; Heart Failure; Humans; Nicardipine; Nifedipine; Ventricular Dysfunction, Left; Verapamil

1997
A review of calcium channel antagonists in the treatment of pediatric hypertension.
    Paediatric drugs, 2006, Volume: 8, Issue:6

    Topics: Amiodarone; Calcium Channel Blockers; Child; Felodipine; Humans; Hypertension; Isradipine; Nicardipine; Nifedipine; Verapamil

2006

Trials

7 trial(s) available for verapamil and felodipine

ArticleYear
Acute haemodynamic effects of felodipine and verapamil in man, singly and with metoprolol.
    Drugs, 1985, Volume: 29 Suppl 2

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Interactions; Electrocardiography; Felodipine; Heart Rate; Hemodynamics; Humans; Male; Metoprolol; Nifedipine; Regional Blood Flow; Stroke Volume; Vascular Resistance; Verapamil

1985
Divergent effects of dihydropyridine and phenylalkylamine calcium channel antagonist classes on autonomic function in human hypertension.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:1

    Topics: Aldosterone; Analysis of Variance; Autonomic Nervous System; Baroreflex; Calcium Channel Blockers; Cardiography, Impedance; Chromogranin A; Chromogranins; Epinephrine; Felodipine; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Renin; Sympathetic Nervous System; Time Factors; Verapamil

1995
The role of atrial natriuretic peptide in the diuretic effect of Ca2+ entry blockers.
    European journal of pharmacology, 1993, Mar-16, Volume: 233, Issue:1

    Topics: Adult; Aged; Aldosterone; Atrial Natriuretic Factor; Blood Pressure; Calcium Channel Blockers; Diuretics; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Natriuresis; Nifedipine; Renin; Renin-Angiotensin System; Verapamil

1993
Comparison of verapamil versus felodipine on heart rate variability after acute myocardial infarction.
    The American journal of cardiology, 1997, Mar-01, Volume: 79, Issue:5

    Topics: Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Electrocardiography, Ambulatory; Felodipine; Female; Follow-Up Studies; Forecasting; Heart Rate; Humans; Male; Middle Aged; Myocardial Infarction; Single-Blind Method; Thrombolytic Therapy; Time Factors; Treatment Outcome; Verapamil

1997
Interaction between cyclosporine A and verapamil, felodipine, and isradipine.
    Nephron, 1999, Volume: 81, Issue:1

    Topics: Adult; Calcium Channel Blockers; Cyclosporine; Drug Interactions; Felodipine; Female; Humans; Immunosuppressive Agents; Isradipine; Kidney Transplantation; Male; Verapamil

1999
Comparison of verapamil versus felodipine on heart rate variability in hypertensive patients.
    Journal of hypertension, 1999, Volume: 17, Issue:5

    Topics: Aged; Blood Pressure; Calcium Channel Blockers; Delayed-Action Preparations; Felodipine; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Single-Blind Method; Time Factors; Verapamil

1999
Optimal treatment of obesity-related hypertension: the Hypertension-Obesity-Sibutramine (HOS) study.
    Circulation, 2007, Apr-17, Volume: 115, Issue:15

    Topics: Adult; Aged; Antihypertensive Agents; Appetite Depressants; Blood Pressure; Body Weight; Cyclobutanes; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Felodipine; Female; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Metoprolol; Middle Aged; Obesity; Prospective Studies; Ramipril; Treatment Outcome; Verapamil

2007

Other Studies

61 other study(ies) available for verapamil and felodipine

ArticleYear
Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein.
    Biochemical pharmacology, 1992, Jun-23, Volume: 43, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Biological Transport; Calcium Channel Blockers; Cell Line; Dihydropyridines; Drug Resistance; Haplorhini; Immunoblotting; Membrane Glycoproteins; Mice; RNA, Messenger; Stereoisomerism; Verapamil; Vinblastine

1992
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
    Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

    Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors

2001
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Extrapolation of preclinical pharmacokinetics and molecular feature analysis of "discovery-like" molecules to predict human pharmacokinetics.
    Drug metabolism and disposition: the biological fate of chemicals, 2006, Volume: 34, Issue:7

    Topics: Animals; Biometry; Dogs; Drug Evaluation, Preclinical; Haloperidol; Haplorhini; Humans; Injections, Intravenous; Liver; Liver Circulation; Metabolic Clearance Rate; Mifepristone; Molecular Structure; Molecular Weight; Rats; Reproducibility of Results

2006
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:2

    Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols

2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
    Bioorganic & medicinal chemistry, 2014, Jan-01, Volume: 22, Issue:1

    Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels

2014
Evaluation of the effects of felodipine, verapamil and hydralazine on the survival rate of rats subjected to lethal effects of oxygen free radicals.
    Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 346, Issue:4

    Topics: Animals; Blood Pressure; Creatine Kinase; Felodipine; Heart Rate; Hydralazine; Male; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Survival Rate; Verapamil; Xanthine; Xanthine Oxidase; Xanthines

1992
Effect of chemically different calcium antagonists on lipid profile in rats fed on a high fat diet.
    Indian journal of experimental biology, 1992, Volume: 30, Issue:4

    Topics: Animals; Blood; Calcium; Clofibrate; Dietary Fats; Diltiazem; Felodipine; Lipids; Male; Nifedipine; Nimodipine; Rats; Rats, Inbred Strains; Verapamil

1992
Microvascular actions of calcium channel antagonists.
    European journal of pharmacology, 1991, Jun-06, Volume: 198, Issue:2-3

    Topics: Animals; Arterioles; Blood Pressure; Calcium Channel Blockers; Calcium Channels; Felodipine; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Inbred SHR; Vasoconstriction; Vasodilation; Venules; Verapamil

1991
Hemodynamic effects of calcium antagonists with high or low vascular selectivity.
    Journal of cardiovascular pharmacology, 1990, Volume: 15 Suppl 4

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Felodipine; Heart; Hemodynamics; Male; Muscle, Smooth, Vascular; Myocardial Contraction; Rats; Rats, Inbred SHR; Vascular Resistance; Verapamil

1990
Antagonistic effects of dihydropyridines and verapamil on CaCl2 and 5-HT-evoked contraction in porcine coronary artery.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1991, Volume: 12, Issue:5

    Topics: Animals; Calcium Chloride; Coronary Vessels; Dihydropyridines; Felodipine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Nimodipine; Serotonin Antagonists; Swine; Verapamil

1991
Protective effects of felodipine and verapamil against imipramine-induced lethal cardiac conduction disturbances in the anaesthetized rat.
    Cardiovascular drugs and therapy, 1991, Volume: 5, Issue:2

    Topics: Animals; Dose-Response Relationship, Drug; Felodipine; Heart Conduction System; Hemodynamics; Imipramine; Male; Rats; Rats, Inbred WKY; Verapamil

1991
Acute haemodynamic effects of felodipine, verapamil and hydralazine in the anaesthetized dog.
    Pharmacology & toxicology, 1991, Volume: 68, Issue:4

    Topics: Animals; Catecholamines; Dogs; Felodipine; Hemodynamics; Hydralazine; Verapamil

1991
Effect of some drugs on thromboplastin activity in mouse trophoblast cells in vitro and in vivo.
    Biochemical pharmacology, 1986, Oct-15, Volume: 35, Issue:20

    Topics: 1-Methyl-3-isobutylxanthine; Adenine; Adenosine; Animals; Calcium Channel Blockers; Dinoprostone; Felodipine; Female; Gallic Acid; Methylation; Mice; Monensin; Nifedipine; Nitrendipine; Pregnancy; Prostaglandins E; Thromboplastin; Trophoblasts; Tubercidin; Verapamil

1986
Vascular versus myocardial selectivity of calcium antagonists studied by concentration-time-effect relations.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 1

    Topics: Animals; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Felodipine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nitrendipine; Papillary Muscles; Rats; Rats, Inbred Strains; Time Factors; Verapamil

1987
Disparate effects of angiotensin converting enzyme inhibitor and calcium blocker treatment on the preservation of renal structure and function following subtotal nephrectomy or streptozotocin-induced diabetes in the rat.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enalapril; Felodipine; Hypertension; Kidney Failure, Chronic; Nephrectomy; Nitrendipine; Proteinuria; Rats; Rats, Inbred Strains; Verapamil

1987
Studies on the site of the interaction between alpha 1-adrenoceptors and 5-HT2 receptors in rat tail arteries.
    Journal of cardiovascular pharmacology, 1988, Volume: 11 Suppl 1

    Topics: Animals; Arteries; Binding Sites; Diltiazem; Felodipine; In Vitro Techniques; Male; Manganese; Muscle Contraction; Muscle, Smooth, Vascular; Nitrendipine; Phenylephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Receptors, Serotonin; Serotonin; Tail; Verapamil

1988
Effects of felodipine and verapamil on transmission in the isolated superior cervical ganglion of the rat.
    Archives internationales de pharmacodynamie et de therapie, 1987, Volume: 288, Issue:1

    Topics: Action Potentials; Animals; Autonomic Nervous System; Calcium Channel Blockers; Felodipine; Ganglia, Spinal; Hexamethonium Compounds; In Vitro Techniques; Nitrendipine; Rats; Synaptic Transmission; Verapamil

1987
Influence of felodipine and verapamil on the sympathetic transmitter release and on the pre- and post-junctional effects of exogenous noradrenaline in the perfused rat kidney.
    Drugs, 1985, Volume: 29 Suppl 2

    Topics: Animals; Antihypertensive Agents; Cocaine; Electric Stimulation; Felodipine; In Vitro Techniques; Kidney; Male; Neuromuscular Junction; Neurotransmitter Agents; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Verapamil

1985
Manganese can inhibit or potentiate contractile responses in mesenteric portal vein.
    Canadian journal of physiology and pharmacology, 1988, Volume: 66, Issue:6

    Topics: Animals; Barium; Calcium; Felodipine; Gallopamil; In Vitro Techniques; Male; Manganese; Mesenteric Veins; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Spectrophotometry, Atomic; Strontium; Tissue Distribution; Verapamil

1988
Comparative effects of verapamil, diltiazem and felodipine during experimental digitalis-induced arrhythmias.
    Pharmacology, 1987, Volume: 34, Issue:2-3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Diltiazem; Dogs; Felodipine; Female; Male; Nitrendipine; Ouabain; Verapamil

1987
Low potency of Ca antagonists in smooth muscle from different levels of the respiratory tract.
    Acta physiologica Scandinavica, 1987, Volume: 131, Issue:2

    Topics: Animals; Bronchi; Calcium Channel Blockers; Felodipine; Female; Gallopamil; Guinea Pigs; In Vitro Techniques; Lanthanum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Nitrendipine; Rats; Rats, Inbred Strains; Respiratory Muscles; Trachea; Verapamil

1987
Calcium dependence of histamine-induced increases in capillary permeability in isolated perfused rat hindquarters.
    Acta physiologica Scandinavica, 1986, Volume: 128, Issue:2

    Topics: Animals; Calcium; Capillary Permeability; Capillary Resistance; Felodipine; Hindlimb; Histamine; Magnesium; Male; Nitrendipine; Perfusion; Rats; Rats, Inbred Strains; Verapamil

1986
Effects of verapamil, diltiazem, nisoldipine and felodipine on sarcoplasmic reticulum.
    European journal of pharmacology, 1984, May-04, Volume: 100, Issue:3-4

    Topics: Animals; Calcium Channel Blockers; Calcium-Transporting ATPases; Centrifugation, Density Gradient; Diltiazem; Dogs; Felodipine; In Vitro Techniques; Microsomes; Muscles; Myocardium; Nifedipine; Nisoldipine; Potassium Chloride; Rabbits; Sarcoplasmic Reticulum; Species Specificity; Verapamil

1984
Effects of felodipine, nifedipine and verapamil on cytosolic Ca2+ and contraction in vascular smooth muscle.
    European journal of pharmacology, 1993, Mar-30, Volume: 234, Issue:1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cytosol; Felodipine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Norepinephrine; Potassium; Rabbits; Rats; Rats, Wistar; Verapamil

1993
Membrane stretch evoked by cell swelling increases contractile activity in vascular smooth muscle through dihydropyridine-sensitive pathways.
    Acta physiologica Scandinavica, 1994, Volume: 152, Issue:4

    Topics: Animals; Calcium; Calcium Channel Blockers; Cell Membrane; Cell Size; Dihydropyridines; Diltiazem; Felodipine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Osmosis; Portal Vein; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Verapamil

1994
Effects of nimodipine, felodipine, and verapamil on isolated human arteries.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1995, Volume: 16, Issue:1

    Topics: Adult; Calcium Chloride; Felodipine; Female; Humans; In Vitro Techniques; Male; Mesenteric Arteries; Middle Aged; Muscle Contraction; Muscle, Smooth, Vascular; Nimodipine; Norepinephrine; Renal Artery; Verapamil

1995
Adverse Drug Reactions Advisory Committee. Gynaecomastia in association with calcium antagonists.
    The Medical journal of Australia, 1994, Sep-05, Volume: 161, Issue:5

    Topics: Adult; Aged; Calcium Channel Blockers; Diltiazem; Felodipine; Gynecomastia; Humans; Male; Middle Aged; Nifedipine; Verapamil

1994
Use of two in vitro glomerular models to study the renal vasoreactivity of cyclosporine.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Analysis of Variance; Animals; Calcium Channel Blockers; Cells, Cultured; Cyclosporine; Dose-Response Relationship, Drug; Felodipine; Glomerular Mesangium; In Vitro Techniques; Kidney Cortex; Kidney Glomerulus; Kinetics; Nifedipine; Rats; Rats, Sprague-Dawley; Time Factors; Vasoconstriction; Verapamil

1994
Dihydropyridine Ca2+ channel antagonists inhibit the salvage pathway for DNA synthesis in human vascular smooth muscle cells.
    European journal of pharmacology, 1993, Feb-15, Volume: 244, Issue:3

    Topics: Calcium Channel Blockers; Cell Division; Cells, Cultured; Dihydropyridines; Diltiazem; DNA; Epidermal Growth Factor; Felodipine; Gene Expression Regulation; Genes, fos; Humans; Immunoblotting; Mammary Arteries; Muscle, Smooth, Vascular; Nisoldipine; Thymidine; Verapamil

1993
Ca2+ channel blockers modulate metabolism of collagens within the extracellular matrix.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, May-28, Volume: 93, Issue:11

    Topics: Amlodipine; Becaplermin; Calcium Channel Blockers; Cells, Cultured; Collagen; Collagenases; Dihydropyridines; Diltiazem; Enzyme Activation; Extracellular Matrix; Felodipine; Fibroblasts; Humans; Kinetics; Lung; Metalloendopeptidases; Muscle, Smooth, Vascular; Nitrobenzenes; Piperazines; Platelet-Derived Growth Factor; Procollagen; Proline; Proto-Oncogene Proteins c-sis; Transcription, Genetic; Verapamil

1996
Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation.
    Hypertension research : official journal of the Japanese Society of Hypertension, 1996, Volume: 19, Issue:4

    Topics: Adenosine Diphosphate; Animals; Antioxidants; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Diltiazem; Felodipine; Fumarates; Heart; Iron; Lipid Peroxidation; Male; Myocardium; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Verapamil

1996
Effects of calcium blockers on the cytosolic calcium, H2O2 production and elastase release in human neutrophils.
    Pharmacology & toxicology, 1996, Volume: 79, Issue:6

    Topics: Calcium; Calcium Channel Blockers; Cytosol; Felodipine; Humans; Hydrogen Peroxide; Leukocyte Elastase; Neutrophil Activation; Neutrophils; Nimodipine; Verapamil

1996
Effects of 5HT2 receptor antagonists on responses to potassium depolarization in rat isolated aorta.
    Clinical and experimental pharmacology & physiology, 1997, Volume: 24, Issue:1

    Topics: Animals; Aorta, Thoracic; Cinnarizine; Cyproheptadine; Diltiazem; Drug Synergism; Felodipine; Female; In Vitro Techniques; Ketanserin; Male; Mianserin; Muscle Contraction; Nifedipine; Potassium; Prazosin; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Reproducibility of Results; Ritanserin; Serotonin Antagonists; Verapamil

1997
Verapamil accelerates the transition to heart failure in obese, hypertensive, female SHHF/Mcc-fa(cp) rats.
    Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:6

    Topics: Animals; Blood Pressure; Brain; Calcium Channel Blockers; Felodipine; Female; Heart; Heart Failure; Hypertension; In Vitro Techniques; Myocardium; Myosins; Organ Size; Rats; Rats, Inbred SHR; Verapamil

1997
Evaluation of pre-ECS antihypertensive drug administration in the attenuation of ECS-induced retrograde amnesia.
    Convulsive therapy, 1997, Volume: 13, Issue:3

    Topics: Amnesia, Retrograde; Animals; Antihypertensive Agents; Blood-Brain Barrier; Calcium Channel Blockers; Electroconvulsive Therapy; Felodipine; Injections, Intraperitoneal; Male; Maze Learning; Mental Recall; Premedication; Rats; Rats, Sprague-Dawley; Vasodilator Agents; Verapamil

1997
[Stable angina pectoris: what is the role of calcium antagonists?].
    Giornale italiano di cardiologia, 1997, Volume: 27, Issue:10

    Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Felodipine; Humans; Metoprolol; Multicenter Studies as Topic; Nifedipine; Randomized Controlled Trials as Topic; Verapamil

1997
Electrophysiological effects of felodipine on guinea pig papillary muscles.
    Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1996, Volume: 17, Issue:3

    Topics: Action Potentials; Animals; Calcium Channel Blockers; Electrophysiology; Felodipine; Female; Guinea Pigs; Male; Nifedipine; Papillary Muscles; Patch-Clamp Techniques; Verapamil

1996
Class differences in the effects of calcium channel blockers in the rat remnant kidney model.
    Kidney international, 1999, Volume: 55, Issue:5

    Topics: Animals; Blood Pressure; Calcium Channel Blockers; Diltiazem; Disease Models, Animal; Drinking; Felodipine; Glomerulosclerosis, Focal Segmental; Homeostasis; Hypertension, Renal; Hypertrophy; Kidney Glomerulus; Male; Nephrectomy; Proteinuria; Radio Waves; Rats; Rats, Sprague-Dawley; Telemetry; Verapamil

1999
Comparison of verapamil and felodipine treatment on lipid and glucose metabolism in obese female SHHF/Mcc-facp rats.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1999, Volume: 221, Issue:3

    Topics: Age Factors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Calcium Channel Blockers; Cardiomegaly; Cholesterol; Eating; Felodipine; Female; Glucose; Lipid Metabolism; Lipoproteins; Obesity; Rats; Rats, Inbred Strains; Triglycerides; Verapamil

1999
Studies on the interactions between the angiotensin converting enzyme inhibitor enalaprilat and calcium antagonists in rats.
    Journal of hypertension, 1996, Volume: 14, Issue:1

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Calcium Channel Blockers; Cinnarizine; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Enalaprilat; Felodipine; Female; Male; Models, Animal; Models, Cardiovascular; Rats; Rats, Sprague-Dawley; Verapamil

1996
Calcium channel antagonists and inhibition of human sphincter of Oddi contractions.
    Scandinavian journal of gastroenterology, 2005, Volume: 40, Issue:12

    Topics: Calcium Channel Blockers; Felodipine; Humans; Muscle Contraction; Muscle, Smooth; Nifedipine; Sphincter of Oddi; Stimulation, Chemical; Tissue Culture Techniques; Verapamil

2005
Competitive and cooperative effects of Bay K8644 on the L-type calcium channel current inhibition by calcium channel antagonists.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Algorithms; Allosteric Regulation; Animals; Binding Sites; Binding, Competitive; Calcium; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Diltiazem; Dose-Response Relationship, Drug; Drug Interactions; Felodipine; Ion Channel Gating; Male; Membrane Potentials; Models, Biological; Myocytes, Cardiac; Patch-Clamp Techniques; Protein Binding; Rats; Rats, Wistar; Verapamil

2007
Use of clopidogrel and calcium channel blockers and risk of major adverse cardiovascular events.
    European journal of clinical investigation, 2012, Volume: 42, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angioplasty, Balloon, Coronary; Calcium Channel Blockers; Cardiovascular Diseases; Child; Child, Preschool; Clopidogrel; Cohort Studies; Denmark; Drug Interactions; Felodipine; Female; Humans; Infant; Male; Middle Aged; Platelet Aggregation Inhibitors; Proportional Hazards Models; Risk; Stents; Ticlopidine; Verapamil; Young Adult

2012
Evaluation of first-pass cytochrome P4503A (CYP3A) and P-glycoprotein activities using felodipine and hesperetin in combination in Wistar rats and everted rat gut sacs in vitro.
    Phytotherapy research : PTR, 2014, Volume: 28, Issue:5

    Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cytochrome P-450 CYP3A; Felodipine; Half-Life; Hesperidin; Ileum; In Vitro Techniques; Intestinal Absorption; Male; Rats; Rats, Wistar; Verapamil

2014