verapamil and enalapril

verapamil has been researched along with enalapril in 83 studies

Research

Studies (83)

TimeframeStudies, this research(%)All Research%
pre-19909 (10.84)18.7374
1990's34 (40.96)18.2507
2000's23 (27.71)29.6817
2010's17 (20.48)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W1
Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Avdeef, A; Tam, KY1
Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bartolucci, G; Coronnello, M; Dei, S; Manetti, D; Romanelli, MN; Salerno, M; Teodori, E; Udomtanakunchai, C1
Frattola, A; Mancia, G; Omboni, S; Ravogli, A; Villani, A1
Donato, L; Marabotti, C; Neglia, D; Palombo, C; Parodi, O; Sambuceti, G1
Beretta-Piccoli, C; Ferrari, P; Ferrier, C; Keller, U; Riesen, WF; Weidmann, P2
Angermann, CE; Dominiak, P; Gerzer, R; Kemkes, BM; Spes, CH; Stempfle, HU; Theisen, K; Weil, J1
Andersen, GN1
Amery, A; Fagard, R; Lijnen, P; Vanhees, L1
Ayache, AS; Groshar, D; Traub, YM1
Angermann, CE; Dominiak, P; Kemkes, BM; Spes, CH; Theisen, K; Willems, S2
Fagher, B; Henningsen, NC; Hulthén, UL; Katzman, P; Thulin, T1
Fogo, A; Ichikawa, I; Yared, A; Yoshida, Y1
Bassett, AH; el Nahas, AM; Le Carpentier, JE; Wight, JP1
Fagher, B; Henningsen, N; Hulthén, L; Katzman, P; Thulin, T1
Cubela, R; Debrevi, L; Jackson, B; Johnston, CI; Whitty, M1
Bianco, G; Cellamare, G; Poppa, E; Sgobba, G1
Bock, HA; Brunner, FP; Hermle, M; Mihatsch, MJ; Thiel, G1
Angermann, CE; Anthuber, M; Kemkes, BM; Spes, CH; Theisen, K1
Jackson, B; Whitty, MR1
Koster, M1
Birkenhäger, WH; de Leeuw, PW; van Soest, GA1
Lowenthal, DT1
Catalano, M; Libretti, A1
Cargo, P; Ferdinand, KC; Laine, H; Lefkowitz, M; Levine, JH1
Collins, TJ; Mehra, MR; Ramee, SR; Smart, FW; Stapleton, DD; Ventura, HO1
Dämmrich, J; Heidland, A; Ling, H; Schaefer, L; Schaefer, RM; Suzuki, H; Teschner, M1
Barrientos, A; Borque, M; González-Mate, A; Herrero, JA; Marcello, M; Torralbo, A; Trobo, JI; Velasco, E1
Carotenuto, A; Cuocolo, A; de Divitiis, M; de Divitiis, O; Di Somma, S; Galderisi, M; Paulucci, A1
Cohen, EP; Fish, BL; Hill, P; Moulder, JE1
Karlson-Stiber, C; Ostergren, J; Rosenberg, J; Svensson, P1
Bujor, MA; Davis, BB; Myles, PS; Olenikov, I1
Arvidsson, N; Herlitz, H; Lukes, D; Mjörnstedt, L; Olausson, M2
Agostoni, P; Guazzi, M; Loaldi, A1
Fletcher, RD; Kokkinos, PF; Narayan, P; Papademetriou, V; Tsagadopoulos, D1
Cohen, A; Erlich, Y; Rosenmann, E; Rosenthal, T1
Gallopin, M; Giorgetti, A; L'Abbate, A; Marabotti, C; Neglia, D; Palombo, C; Parodi, O; Sambuceti, G; Simonetti, I1
Cholewa, M; Gralec, M; Piusińska-Macoch, A; Sułek, K1
Oken, RJ1
Iversen, BM; Kvam, FI; Ofstad, J1
Alsina, J; Grinyó, JM; Hueso, M; Martínez-Castelao, A; Rejas, J; Sanz, V1
Gordeladze, JO; Jynge, P; Sellevold, OF1
Kim, SB; Lee, SK; Park, JS; Park, JY; Park, SK; Yang, WS; Yu, ES1
Mandarim-de-Lacerda, CA; Meirelles Pereira, LM1
Guelpa, G1
Mandarim-de-Lacerda, CA; Pereira, LM4
Candy, GP; Den Hond, E; Libhaber, C; Libhaber, E; Radevski, IV; Sareli, P; Skudicky, D; Staessen, JA; Valtchanova, ZP; Wang, JG1
Abrignani, MG; Barbagallo, M; Dominguez, LJ; Nardi, E; Novo, G; Novo, S; Strano, A1
Fernández, R; Garrido, J; Puig, JG; Redon, J; Rodríguez-Pérez, JC1
Anders, RJ; Bakris, G; Fagan, T; Ram, V; Sica, D; Vaitkus, PT1
Candy, G; Libhaber, E; Radevski, I; Sareli, P; Skudicky, D; Staessen, JA; Thijs, L; Tshele, E; Valtchanova, Z; Wang, JG1
Anders, RJ; Calhoun, D; Mansoor, GA; Sica, DA; White, WB1
Madeira, AC; Mandarim-de-Lacerda, CA; Pereira, LM1
Iversen, BM; Myking, O; Ofstad, J; Svarstad, E1
Bezerra, DG; Mandarim-de-Lacerda, CA; Pereira, LM1
Karpov, IuA1
Antopolsky, M; Chajek-Shaul, T; Hasin, T; Leibowitz, D1
Antequera, R; Cedeño, J; Estrada, O; León, L; Romero-Vecchione, E; Rosa, F; Vásquez, J1
Austin, RP; Barton, P; Wenlock, MC1
Efimova, IIu; Kalashnikova, TP; Lishmanov, IuB1
Linnet, K; Rasmussen, HB; Thomsen, R1
Abolghasemi, R; Argani, H; Atabak, S; Rahmani, L; Taziki, O; Zangneh, HF1
Jansook, P; Loftsson, T; Muankaew, C; Stefánsson, E1
Caprioli, RM; Chumbley, CW; Hachey, BC; Norris, JL; Prentice, BM1
Alexandrescu, D; Fabi, S; Fitzpatrick, RE; Goldman, MP; Yeh, LC1

Reviews

6 review(s) available for verapamil and enalapril

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Ambulatory blood pressure monitoring.
    Drugs, 1992, Volume: 44 Suppl 1

    Topics: Blood Pressure Monitors; Double-Blind Method; Enalapril; Humans; Hypertension; Nitrendipine; Verapamil

1992
Regional myocardial blood flow and coronary reserve in hypertensive patients. The effect of therapy.
    Drugs, 1992, Volume: 44 Suppl 1

    Topics: Adult; Coronary Circulation; Enalapril; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Regional Blood Flow; Verapamil

1992
[Ischemic heart disease combined with hypertension: peculiarities of course and selection of therapy].
    Kardiologiia, 2005, Volume: 45, Issue:12

    Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Calcium Channel Blockers; Controlled Clinical Trials as Topic; Enalapril; Female; Humans; Hypertension; Indoles; Male; Middle Aged; Myocardial Ischemia; Nifedipine; Perindopril; Placebos; Risk Factors; Surveys and Questionnaires; Time Factors; Vasodilator Agents; Verapamil

2005
Comparative Results in Treatment of Keloids With Intralesional 5-FU/Kenalog, 5-FU/Verapamil, Enalapril Alone,Verapamil Alone, and Laser: A Case Report and Review of the Literature.
    Journal of drugs in dermatology : JDD, 2016, Nov-01, Volume: 15, Issue:11

    Topics: Adult; Drug Therapy, Combination; Enalapril; Fluorouracil; Humans; Injections, Intralesional; Keloid; Laser Therapy; Male; Treatment Outcome; Triamcinolone Acetonide; Verapamil

2016

Trials

21 trial(s) available for verapamil and enalapril

ArticleYear
Regional myocardial blood flow and coronary reserve in hypertensive patients. The effect of therapy.
    Drugs, 1992, Volume: 44 Suppl 1

    Topics: Adult; Coronary Circulation; Enalapril; Female; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Regional Blood Flow; Verapamil

1992
Swiss hypertension treatment programme with verapamil and/or enalapril in diabetic patients.
    Drugs, 1992, Volume: 44 Suppl 1

    Topics: Adolescent; Adult; Aged; Blood Glucose; Blood Pressure; Creatinine; Diabetes Complications; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Lipids; Male; Middle Aged; Switzerland; Verapamil

1992
Effect of antihypertensive medication on endurance exercise capacity in hypertensive sportsmen.
    Journal of hypertension, 1991, Volume: 9, Issue:11

    Topics: Adult; Antihypertensive Agents; Atenolol; Double-Blind Method; Enalapril; Exercise Test; Humans; Hypertension; Male; Physical Endurance; Sports; Verapamil

1991
Antihypertensive therapy with Ca2+. Antagonist verapamil and/or ACE inhibitor enalapril in NIDDM patients.
    Diabetes care, 1991, Volume: 14, Issue:10

    Topics: Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Enalapril; Female; Glycated Hemoglobin; Humans; Hypertension; Male; Middle Aged; Proteinuria; Verapamil

1991
The effect of enalapril and calcium antagonists on blood pressure and cerebral perfusion in elderly hypertensives.
    Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1991, Volume: 9, Issue:6

    Topics: Aged; Blood Pressure; Cerebrovascular Circulation; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Single-Blind Method; Verapamil

1991
Antihypertensive efficacy and tolerability of enalapril and slow-release verapamil in essential hypertension: a double-blind, cross-over study.
    Journal of internal medicine, 1991, Volume: 230, Issue:3

    Topics: Adult; Age Factors; Aged; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Electrocardiography; Enalapril; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Quality of Life; Renin; Single-Blind Method; Verapamil

1991
Antihypertensive and renal effects of enalapril and slow-release verapamil in essential hypertension. A double-blind, randomized study.
    European journal of clinical pharmacology, 1990, Volume: 39 Suppl 1

    Topics: Adult; Aldosterone; Angiotensin II; Blood Pressure; Delayed-Action Preparations; Double-Blind Method; Enalapril; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Renin; Verapamil

1990
Lipid profile during antihypertensive treatment. The SLIP Study Group. Study on Lipids with Isoptin Press.
    Drugs, 1993, Volume: 46 Suppl 2

    Topics: Aged; Analysis of Variance; Antihypertensive Agents; Blood Pressure; Delayed-Action Preparations; Drug Therapy, Combination; Electrocardiography; Enalapril; Female; Heart Conduction System; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Verapamil

1993
Additive effects of verapamil and enalapril in the treatment of mild to moderate hypertension.
    American journal of hypertension, 1995, Volume: 8, Issue:5 Pt 1

    Topics: Adult; Aged; Analysis of Variance; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Quality of Life; Surveys and Questionnaires; Verapamil

1995
Favourable interaction of calcium antagonist plus ACE inhibitor on cardiac haemodynamics in treating hypertension: rest and effort evaluation.
    Journal of human hypertension, 1995, Volume: 9, Issue:3

    Topics: Adult; Aged; Blood Pressure; Drug Combinations; Drug Interactions; Enalapril; Exercise; Female; Heart; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Rest; Verapamil

1995
Comparative effects of enalapril and verapamil on myocardial blood flow in systemic hypertension.
    Circulation, 1997, Aug-05, Volume: 96, Issue:3

    Topics: Antihypertensive Agents; Calcium Channel Blockers; Cardiac Pacing, Artificial; Coronary Circulation; Dipyridamole; Enalapril; Female; Humans; Hypertension; Male; Middle Aged; Reproducibility of Results; Single-Blind Method; Tomography, Emission-Computed; Vasodilator Agents; Verapamil

1997
[Changes in the quality of life influenced by treatment of primary arterial hypertension].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 1997, Volume: 2, Issue:7

    Topics: Adult; Antihypertensive Agents; Atenolol; Enalapril; Humans; Hypertension; Male; Middle Aged; Quality of Life; Verapamil

1997
Treatment of hypertension after renal transplantation: long-term efficacy of verapamil, enalapril, and doxazosin.
    Kidney international. Supplement, 1998, Volume: 68

    Topics: Adult; Antihypertensive Agents; Calcium Channel Blockers; Doxazosin; Enalapril; Female; Follow-Up Studies; Graft Survival; Humans; Hypercholesterolemia; Hypertension, Renal; Kidney Failure, Chronic; Kidney Transplantation; Longitudinal Studies; Male; Middle Aged; Postoperative Complications; Verapamil

1998
Efficacy of different drug classes used to initiate antihypertensive treatment in black subjects: results of a randomized trial in Johannesburg, South Africa.
    Archives of internal medicine, 2001, Apr-09, Volume: 161, Issue:7

    Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Black People; Blood Pressure; Calcium Channel Blockers; Diastole; Diuretics; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nifedipine; Practice Guidelines as Topic; Proportional Hazards Models; Sodium Chloride Symporter Inhibitors; South Africa; Time Factors; Treatment Outcome; Vasodilator Agents; Verapamil

2001
Effects of drug therapy on cardiac arrhythmias and ischemia in hypertensives with LVH.
    American journal of hypertension, 2001, Volume: 14, Issue:7 Pt 1

    Topics: Adult; Aged; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Atenolol; Blood Pressure; Electrocardiography, Ambulatory; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Myocardial Ischemia; Treatment Outcome; Verapamil

2001
Effect of two antihypertensive combinations on metabolic control in type-2 diabetic hypertensive patients with albuminuria: a randomised, double-blind study.
    Journal of human hypertension, 2001, Volume: 15, Issue:12

    Topics: Aged; Albuminuria; Analysis of Variance; Antihypertensive Agents; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Enalapril; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Indoles; Male; Middle Aged; Multivariate Analysis; Probability; Prospective Studies; Spain; Treatment Outcome; Verapamil

2001
A comparative trial of controlled-onset, extended-release verapamil, enalapril, and losartan on blood pressure and heart rate changes.
    American journal of hypertension, 2002, Volume: 15, Issue:1 Pt 1

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; Enalapril; Female; Heart Rate; Humans; Hypertension; Losartan; Male; Middle Aged; Vasodilator Agents; Verapamil

2002
Relationship between treatment-induced changes in left ventricular mass and blood pressure in black african hypertensive patients: results of the Baragwanath Trial.
    Circulation, 2002, Feb-19, Volume: 105, Issue:7

    Topics: Angiotensin-Converting Enzyme Inhibitors; Black People; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diastole; Diuretics; Echocardiography; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Methyldopa; Middle Aged; Nifedipine; Patient Compliance; Regression Analysis; South Africa; Systole; Verapamil

2002
Preventing increases in early-morning blood pressure, heart rate, and the rate-pressure product with controlled onset extended release verapamil at bedtime versus enalapril, losartan, and placebo on arising.
    American heart journal, 2002, Volume: 144, Issue:4

    Topics: Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Delayed-Action Preparations; Double-Blind Method; Electrocardiography, Ambulatory; Enalapril; Female; Heart Rate; Humans; Hypertension; Losartan; Male; Statistics, Nonparametric; Systole; Verapamil

2002
[The impact of antihypertensive therapy on cerebral hemodynamics in patients with metabolic syndrome].
    Klinicheskaia meditsina, 2012, Volume: 90, Issue:8

    Topics: Antihypertensive Agents; Biological Availability; Blood Pressure Monitoring, Ambulatory; Brain; Cerebrovascular Circulation; Drug Therapy, Combination; Enalapril; Female; Humans; Hypertension; Indapamide; Male; Metabolic Syndrome; Middle Aged; Tomography, Emission-Computed, Single-Photon; Treatment Outcome; Verapamil

2012
Effects of oral enalapril and verapamil on dialysis adequacy and solute clearance in chronic ambulatory peritoneal dialysis.
    Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, 2013, Volume: 24, Issue:6

    Topics: Administration, Oral; Adult; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Dialysis Solutions; Enalapril; Female; Humans; Male; Middle Aged; Peritoneal Dialysis, Continuous Ambulatory; Verapamil

2013

Other Studies

57 other study(ies) available for verapamil and enalapril

ArticleYear
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:11

    Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution

2009
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
    Bioorganic & medicinal chemistry, 2009, Oct-01, Volume: 17, Issue:19

    Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
QSAR-based permeability model for drug-like compounds.
    Bioorganic & medicinal chemistry, 2011, Apr-15, Volume: 19, Issue:8

    Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Design and synthesis of new potent N,N-bis(arylalkyl)piperazine derivatives as multidrug resistance (MDR) reversing agents.
    European journal of medicinal chemistry, 2018, Mar-10, Volume: 147

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Dose-Response Relationship, Drug; Drug Design; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; K562 Cells; Molecular Structure; Piperazine; Piperazines; Structure-Activity Relationship; Tumor Cells, Cultured

2018
Effects of graded exercise on blood pressure, heart rate, and plasma hormones in cardiac transplant recipients before and during antihypertensive therapy.
    The Clinical investigator, 1992, Volume: 70, Issue:1

    Topics: Adult; Atrial Natriuretic Factor; Blood Pressure; Cyclic GMP; Drug Therapy, Combination; Enalapril; Epinephrine; Exercise Test; Female; Follow-Up Studies; Furosemide; Heart Rate; Heart Transplantation; Hormones; Humans; Hypertension; Male; Middle Aged; Norepinephrine; Postoperative Complications; Renin; Verapamil

1992
IgA-nephropathia in a patient with ankylosing spondylitis.
    Scandinavian journal of rheumatology, 1992, Volume: 21, Issue:1

    Topics: Enalapril; Glomerulonephritis, IGA; Hemoglobins; Humans; Immunoglobulin A; Kidney; Male; Middle Aged; Spondylitis, Ankylosing; Ultrasonography; Verapamil

1992
Regression of left ventricular hypertrophy in hypertensive heart transplant recipients treated with enalapril, furosemide, and verapamil.
    Circulation, 1991, Volume: 84, Issue:2

    Topics: Adult; Cardiomegaly; Echocardiography; Electrocardiography; Enalapril; Female; Furosemide; Heart Transplantation; Heart Ventricles; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Verapamil

1991
Importance of angiogenic action of angiotensin II in the glomerular growth of maturing kidneys.
    Kidney international, 1990, Volume: 38, Issue:6

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Enalapril; Hydralazine; Kidney Glomerulus; Male; Rats; Verapamil

1990
Effect of treatment with enalapril, verapamil and indomethacin on compensatory renal growth in the rat.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1990, Volume: 5, Issue:9

    Topics: Animals; Body Weight; Enalapril; Hypertrophy; Indomethacin; Kidney; Male; Nephrectomy; Organ Size; Rats; Rats, Inbred Strains; Verapamil

1990
Disparate effects of angiotensin converting enzyme inhibitor and calcium blocker treatment on the preservation of renal structure and function following subtotal nephrectomy or streptozotocin-induced diabetes in the rat.
    Journal of cardiovascular pharmacology, 1987, Volume: 10 Suppl 10

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enalapril; Felodipine; Hypertension; Kidney Failure, Chronic; Nephrectomy; Nitrendipine; Proteinuria; Rats; Rats, Inbred Strains; Verapamil

1987
[Circadian behavior of blood pressure and heart rate following orthotopic heart transplantation. Studies before and during antihypertensive therapy].
    Zeitschrift fur Kardiologie, 1989, Volume: 78, Issue:4

    Topics: Adult; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Enalapril; Female; Furosemide; Heart Rate; Heart Transplantation; Humans; Male; Postoperative Complications; Verapamil

1989
[Calcium antagonists vs ACE inhibitors in the treatment of essential arterial hypertension in the aged].
    Minerva cardioangiologica, 1989, Volume: 37, Issue:3

    Topics: Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diltiazem; Drug Evaluation; Enalapril; Female; Humans; Hypertension; Male; Nifedipine; Verapamil

1989
Long-term enalapril and verapamil in rats with reduced renal mass.
    Kidney international, 1989, Volume: 36, Issue:6

    Topics: Animals; Enalapril; Female; Glomerulonephritis; Hypertension, Renal; Hypertrophy; Kidney; Nephrectomy; Proteinuria; Rats; Rats, Inbred Strains; Time Factors; Verapamil

1989
[Effect of enalapril, furosemide and verapamil on cyclosporin concentration in whole blood].
    Klinische Wochenschrift, 1988, Dec-01, Volume: 66, Issue:23

    Topics: Adult; Cyclosporins; Enalapril; Female; Furosemide; Heart Transplantation; Humans; Hypertension; Lung Transplantation; Male; Middle Aged; Prospective Studies; Verapamil

1988
Diabetic nephropathy in the rat: differing renal effects of an angiotensin converting enzyme inhibitor and a calcium inhibitor.
    Diabetes research (Edinburgh, Scotland), 1988, Volume: 8, Issue:2

    Topics: Animals; Blood Pressure; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Enalapril; Female; Glomerular Filtration Rate; Kidney; Proteinuria; Rats; Rats, Inbred Strains; Reference Values; Verapamil

1988
[Calcium channel blockers and angiotensin converting enzyme inhibitors in the treatment of high blood pressure].
    Nederlands tijdschrift voor geneeskunde, 1986, Aug-23, Volume: 130, Issue:34

    Topics: Calcium Channel Blockers; Captopril; Drug Interactions; Enalapril; Humans; Hypertension; Nifedipine; Oligopeptides; Teprotide; Verapamil

1986
Aldosterone response to antihypertensive treatment.
    Clinical and experimental hypertension. Part A, Theory and practice, 1982, Volume: 4, Issue:9-10

    Topics: Adult; Aged; Aldosterone; Angiotensin II; Antihypertensive Agents; Atenolol; Blood Pressure; Dipeptides; Enalapril; Ethanolamines; Humans; Hypertension; Middle Aged; Prazosin; Pyridazines; Renin; Renin-Angiotensin System; Vasodilator Agents; Verapamil

1982
New drugs for hypertension.
    American family physician, 1984, Volume: 29, Issue:5

    Topics: Antihypertensive Agents; Bumetanide; Diltiazem; Dipeptides; Enalapril; Guanabenz; Guanidines; Humans; Indapamide; Labetalol; Nifedipine; Pindolol; Verapamil

1984
An intravascular ultrasound study of the influence of angiotensin-converting enzyme inhibitors and calcium entry blockers on the development of cardiac allograft vasculopathy.
    The American journal of cardiology, 1995, Apr-15, Volume: 75, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Coronary Disease; Diltiazem; Enalapril; Female; Heart Transplantation; Humans; Hyperplasia; Lisinopril; Male; Middle Aged; Nifedipine; Transplantation, Homologous; Tunica Intima; Ultrasonography, Interventional; Verapamil

1995
Prevention of cardiac hypertrophy in experimental chronic renal failure by long-term ACE inhibitor administration: potential role of lysosomal proteinases.
    American journal of nephrology, 1995, Volume: 15, Issue:2

    Topics: Animals; Cathepsin B; Cathepsin H; Cathepsin L; Cathepsins; Cysteine Endopeptidases; Enalapril; Endopeptidases; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Male; Myocardium; Rats; Rats, Wistar; Renin-Angiotensin System; Verapamil

1995
Alterations in renal endothelin production in rats with reduced renal mass.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1995, Volume: 25, Issue:6

    Topics: Animals; Enalapril; Endothelins; Erythropoietin; Hypertension, Renal; Kidney; Kidney Diseases; Male; Nephrectomy; Radioimmunoassay; Rats; Rats, Wistar; Recombinant Proteins; Verapamil

1995
Prophylaxis of experimental bone marrow transplant nephropathy.
    The Journal of laboratory and clinical medicine, 1994, Volume: 124, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bone Marrow Transplantation; Captopril; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Enalapril; Kidney; Kidney Diseases; Male; Proteinuria; Radiation Injuries, Experimental; Rats; Time Factors; Uremia; Verapamil; Whole-Body Irradiation

1994
[Do ACE inhibitors potentiate snake venom? Severe and prolonged hypotension caused by adder bite].
    Lakartidningen, 1993, Aug-11, Volume: 90, Issue:32-33

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antivenins; Drug Synergism; Enalapril; Humans; Hypotension; Male; Middle Aged; Snake Bites; Time Factors; Verapamil; Viper Venoms

1993
ACE-inhibitors, calcium antagonists and low systemic vascular resistance following cardiopulmonary bypass. A case-control study.
    The Medical journal of Australia, 1993, May-17, Volume: 158, Issue:10

    Topics: Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Captopril; Cardiopulmonary Bypass; Case-Control Studies; Coronary Artery Bypass; Critical Care; Diltiazem; Dopamine; Enalapril; Female; Heart Valves; Humans; Length of Stay; Male; Middle Aged; Nifedipine; Norepinephrine; Retrospective Studies; Single-Blind Method; Syndrome; Vascular Resistance; Verapamil

1993
Rat heart allograft survival after treatment with verapamil, captopril, and enalapril.
    Transplantation proceedings, 1995, Volume: 27, Issue:6

    Topics: Animals; Captopril; Drug Interactions; Enalapril; Graft Rejection; Graft Survival; Heart Transplantation; Immunosuppressive Agents; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Homologous; Verapamil

1995
Ineffectiveness of angiotensin converting enzyme inhibition (enalapril) on overt and silent myocardial ischemia in vasospastic angina and comparison with verapamil.
    Clinical pharmacology and therapeutics, 1996, Volume: 59, Issue:4

    Topics: Angina Pectoris, Variant; Angiotensin-Converting Enzyme Inhibitors; Coronary Angiography; Electrocardiography; Enalapril; Exercise Test; Humans; Male; Middle Aged; Rest; Vasodilator Agents; Verapamil

1996
Effects of aerobic training on exaggerated blood pressure response to exercise in African-Americans with severe systemic hypertension treated with indapamide +/- verapamil +/- enalapril.
    The American journal of cardiology, 1997, May-15, Volume: 79, Issue:10

    Topics: Adult; Aged; Antihypertensive Agents; Black People; Blood Pressure; Combined Modality Therapy; Drug Therapy, Combination; Enalapril; Exercise Therapy; Humans; Hypertension; Indapamide; Male; Middle Aged; Verapamil

1997
Effects of enalapril, losartan, and verapamil on blood pressure and glucose metabolism in the Cohen-Rosenthal diabetic hypertensive rat.
    Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:6

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Disease Models, Animal; Enalapril; Glucose; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred Strains; Tetrazoles; Verapamil

1997
Obsessive-compulsive disorder: cerebral calcium deficiency as a possible etiologic/pathogenetic factor--a case study.
    Medical hypotheses, 1997, Volume: 49, Issue:6

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Brain; Calcium; Calcium Channel Blockers; Enalapril; Humans; Hypertension; Male; Obsessive-Compulsive Disorder; Tachycardia, Paroxysmal; Verapamil

1997
Effects of antihypertensive drugs on autoregulation of RBF and glomerular capillary pressure in SHR.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: Adrenergic alpha-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Capillaries; Doxazosin; Enalapril; Homeostasis; Hypertension; Kidney; Kidney Glomerulus; Male; Nifedipine; Rats; Rats, Inbred SHR; Regional Blood Flow; Renal Circulation; Verapamil

1998
Prolonged rat heart allograft survival after treatment with angiotensin converting enzyme inhibitor or a calcium antagonist.
    Scandinavian journal of urology and nephrology, 1998, Volume: 32, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Captopril; Drug Therapy, Combination; Enalapril; Female; Graft Survival; Heart Transplantation; Immunosuppression Therapy; Male; Rats; Rats, Inbred Strains; Time Factors; Transplantation, Homologous; Verapamil

1998
Beta-adrenergic signalling and threshold adrenaline concentration for induction of fibrillation in the perfused heart pretreated with antihypertensive drugs.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1999, Volume: 199, Issue:3

    Topics: Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Cyclic AMP; Enalapril; Epinephrine; GTP-Binding Proteins; In Vitro Techniques; Male; Metoprolol; Perfusion; Potassium; Rats; Rats, Wistar; Receptors, Adrenergic, beta; Signal Transduction; Timolol; Verapamil

1999
Individual or combined effects of enalapril and verapamil on chronic cyclosporine nephrotoxicity in rats.
    Journal of Korean medical science, 1999, Volume: 14, Issue:6

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium Channel Blockers; Cyclosporine; Drug Therapy, Combination; Enalapril; Endothelin-1; Gene Expression Regulation; Immunosuppressive Agents; Kidney Cortex; Male; Nephritis; Osteopontin; Procollagen; Rats; Rats, Wistar; RNA, Messenger; Sialoglycoproteins; Transforming Growth Factor beta; Verapamil

1999
Effect of antihypertensive drugs on the myocardial microvessels in rats with nitric oxide blockade.
    Pathology, research and practice, 2000, Volume: 196, Issue:5

    Topics: Animals; Antihypertensive Agents; Blood Pressure; Capillaries; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Enalapril; Enzyme Inhibitors; Heart; Hypertension; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Spironolactone; Verapamil

2000
[Diabetic nephropathy with nephrotic syndrome--apropos of 2 cases. Advantages of combined conversion enzyme inhibitor and non-dihydropyridine calcium antagonist treatment].
    Praxis, 2000, Aug-24, Volume: 89, Issue:34

    Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Enalapril; Humans; Indoles; Kidney Function Tests; Male; Middle Aged; Nephrotic Syndrome; Verapamil

2000
Volume-weighted mean nuclear volume and numerical nuclear density in the cardiomyocyte following enalapril and verapamil treatment.
    Virchows Archiv : an international journal of pathology, 2001, Volume: 438, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cell Nucleus; Enalapril; Enzyme Inhibitors; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Rats; Rats, Wistar; Verapamil

2001
Heart biometry and allometry in rats submitted to nitric oxide synthesis blockade and treatment with antihypertensive drugs.
    Annals of anatomy = Anatomischer Anzeiger : official organ of the Anatomische Gesellschaft, 2001, Volume: 183, Issue:2

    Topics: Animals; Antihypertensive Agents; Body Weight; Enalapril; Heart; Heart Ventricles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Organ Size; Rats; Rats, Wistar; Regression Analysis; Spironolactone; Verapamil

2001
The effect of enalapril and verapamil on the left ventricular hypertrophy and the left ventricular cardiomyocyte numerical density in rats submitted to nitric oxide inhibition.
    International journal of experimental pathology, 2001, Volume: 82, Issue:2

    Topics: Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cell Count; Enalapril; Enzyme Inhibitors; Hypertrophy, Left Ventricular; Male; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Plethysmography; Rats; Rats, Wistar; Statistics, Nonparametric; Verapamil

2001
Stereology of cardiac hypertrophy induced by NO blockade in rats treated with enalapril and verapamil.
    Analytical and quantitative cytology and histology, 2001, Volume: 23, Issue:5

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; Calcium Channel Blockers; Cardiomegaly; Enalapril; Male; Necrosis; NG-Nitroarginine Methyl Ester; Rats; Rats, Wistar; Verapamil

2001
Cardiomyocyte volume-weighted nuclear volume and spironolactone therapy in spontaneously hypertensive rats.
    Analytical and quantitative cytology and histology, 2002, Volume: 24, Issue:6

    Topics: Animals; Blood Pressure; Cell Nucleus; Dose-Response Relationship, Drug; Enalapril; Hypertension; Male; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Spironolactone; Time Factors; Verapamil

2002
Effect of light exercise on renal hemodynamics in patients with hypertension and chronic renal disease.
    Scandinavian journal of urology and nephrology, 2002, Volume: 36, Issue:6

    Topics: Adult; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Captopril; Enalapril; Exercise; Female; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension; Kidney Failure, Chronic; Male; Middle Aged; Norepinephrine; Renal Circulation; Renal Plasma Flow, Effective; Verapamil

2002
Aortic wall remodeling in rats with nitric oxide deficiency treated by enalapril or verapamil.
    Pathology, research and practice, 2004, Volume: 200, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Drug Therapy, Combination; Enalapril; Heart Ventricles; Male; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Wistar; Verapamil

2004
The use of low-dose insulin in cardiogenic shock due to combined overdose of verapamil, enalapril and metoprolol.
    Cardiology, 2006, Volume: 106, Issue:4

    Topics: Antihypertensive Agents; Drug Synergism; Enalapril; Female; Humans; Hypoglycemic Agents; Insulin; Metoprolol; Middle Aged; Shock, Cardiogenic; Vasodilator Agents; Verapamil

2006
Cardiovascular excitatory effect on rats of a fraction isolated from the eyestalk of shrimp: Peneaus vanameii.
    Investigacion clinica, 2006, Volume: 47, Issue:2

    Topics: Animal Structures; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Blood Pressure; Calcium Channels; Cardiotonic Agents; Dihydroergotamine; Drug Evaluation, Preclinical; Enalapril; Ganglia, Invertebrate; Heart Rate; Hemodynamics; Hypertension; Male; Motor Neurons; Neuropeptides; Penaeidae; Premedication; Propranolol; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Tachycardia; Tissue Extracts; Verapamil

2006
A kinetic method for the determination of plasma protein binding of compounds unstable in plasma: Specific application to enalapril.
    Journal of pharmaceutical and biomedical analysis, 2011, Jun-01, Volume: 55, Issue:3

    Topics: Adsorption; Animals; Blood Proteins; Centrifugation; Charcoal; Clinical Laboratory Techniques; Dextrans; Dialysis; Dogs; Drug Stability; Enalapril; Guinea Pigs; Humans; In Vitro Techniques; Piperazines; Protein Binding; Purines; Rats; Reproducibility of Results; Sildenafil Citrate; Sulfones; Time Factors; Verapamil; Warfarin

2011
In vitro drug metabolism by human carboxylesterase 1: focus on angiotensin-converting enzyme inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2014, Volume: 42, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Carboxylesterase; Carboxylic Ester Hydrolases; Diltiazem; Drug Interactions; Enalapril; Esters; Humans; Hydrolysis; Inactivation, Metabolic; Indoles; Kinetics; Liver; Microsomes, Liver; Nitrophenols; Prodrugs; Ramipril; Recombinant Proteins; Verapamil

2014
Development of eye drops containing antihypertensive drugs: formulation of aqueous irbesartan/γCD eye drops.
    Pharmaceutical development and technology, 2015, Volume: 20, Issue:5

    Topics: Antihypertensive Agents; Biphenyl Compounds; Enalapril; gamma-Cyclodextrins; Irbesartan; Ophthalmic Solutions; Permeability; Solubility; Tetrazoles; Verapamil

2015
Multiple Time-of-Flight/Time-of-Flight Events in a Single Laser Shot for Improved Matrix-Assisted Laser Desorption/Ionization Tandem Mass Spectrometry Quantification.
    Analytical chemistry, 2016, 10-04, Volume: 88, Issue:19

    Topics: Antihypertensive Agents; Enalapril; Humans; Lasers; Molecular Structure; Promethazine; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Verapamil

2016