verapamil has been researched along with emopamil in 48 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (25.00) | 18.7374 |
| 1990's | 30 (62.50) | 18.2507 |
| 2000's | 2 (4.17) | 29.6817 |
| 2010's | 2 (4.17) | 24.3611 |
| 2020's | 2 (4.17) | 2.80 |
| Authors | Studies |
|---|---|
| Dietel, M; Höllt, V; Kouba, M; Vogt, G | 1 |
| McIntosh, TK; Okiyama, K; Smith, DH; Thomas, MJ | 1 |
| Drummond, JC; Fleischer, JE; Grafe, MR; Nakakimura, K; Scheller, MS; Shapiro, HM; Zornow, MH | 1 |
| Glossmann, H; Mühlbacher, J; Staudinger, R; Zech, C | 1 |
| Busto, R; Dietrich, WD; Ginsberg, MD; Globus, MY; Lin, B; Morikawa, E | 1 |
| Busto, R; Dietrich, WD; Duncan, RC; Ginsberg, MD; Morikawa, E | 1 |
| Block, F; Heim, C; Jaspers, RM; Sontag, KH | 1 |
| Busto, R; Dietrich, WD; Ginsberg, MD; Lin, BW | 1 |
| Bielenberg, GW; Krieglstein, J; Weber, J | 1 |
| Defeudis, FV | 1 |
| Weintraub, MI | 1 |
| Hofmann, HP; Raschack, M; Unger, L | 1 |
| Szabo, L | 1 |
| Hofmann, HP; Szabo, L | 1 |
| Dezsi, L; Kovách, AG; Lohinai, ZS; Nguyen, LT; Pék, L | 1 |
| Kovach, AG; Urbanics, R | 1 |
| Dietrich, WD; Ginsberg, MD; Nakayama, H | 1 |
| Chan, L; Mills, S; Schrier, RW; Schwertschlag, U; Shapiro, JI | 1 |
| Beck, T; Bielenberg, GW; Burniol, M; Krieglstein, J; Sauer, D | 1 |
| Bielenberg, GW; Haubruck, H; Krieglstein, J | 1 |
| Myrdal, PB; Simamora, P; Surakitbanharn, Y; Yalkowsky, SH | 1 |
| Glossmann, H; Grabner, M; Hanner, M; Moebius, FF; Striessnig, J; Weber, F | 1 |
| DeFeo, PA; Ernst, GE; Keith, RA; Mangano, TJ; Warawa, EJ | 1 |
| Heim, C; Sieklucka, M; Sontag, KH | 1 |
| Brendel, R; Elger, B; Seega, J | 1 |
| Navratil, MJ; Rosenberg, GA | 1 |
| Matsumoto, M; Scheller, MS; Strnat, MA; Zornow, MH | 1 |
| Gennarelli, TA; McIntosh, TK; Okiyama, K; Rosenkrantz, TS; Smith, DH | 1 |
| Elger, B; Raschack, M; Seega, J | 1 |
| Grady, DR; Janowsky, D; O'Brien, RA; Pucilowski, O; Rezvani, AH | 1 |
| Cole, DJ; Drummond, JC; Patel, PM; Sano, T | 1 |
| Burrows, GG; Glossmann, H; Moebius, FF; Striessnig, J | 1 |
| Elger, B; Seega, J | 1 |
| Croul, S; Gomi, S; Greenberg, JH; Reivich, M | 1 |
| Plangger, C; Völkl, H | 1 |
| Degtiar, VE; Döring, F; Glossman, H; Grabner, M; Hering, S; Striessnig, J | 1 |
| Bäcker, A; Kramer, HJ; Meyer-Lehnert, H; Rosberg, J | 1 |
| Hunter, AJ | 1 |
| Glossmann, H; Hanner, M; Moebius, FF; Reiter, RJ | 1 |
| Block, F; Schwarz, M | 1 |
| Bouteiller, CL; Casellas, P; De Nys, N; Dupuy, PH; Ferrara, P; Le Fur, G; Loison, G; Paul, R; Rosenfeld, J; Silve, S | 1 |
| McCandless, R; Yalkowsky, SH | 1 |
| Iimura, Y; Ito, K; Kawano, K; Kimura, T; Nagato, S; Norimine, Y; Suzuki, Y; Yamamoto, N; Yonaga, M | 1 |
| Hamano, T; Iimura, Y; Ito, K; Kaneda, Y; Kawano, K; Kimura, M; Kimura, T; Komatsu, M; Nagato, S; Niidome, T; Norimine, Y; Suzuki, Y; Teramoto, T; Yamamoto, N; Yonaga, M | 1 |
| Dreker, T; Grissmer, S; Rossokhin, A; Zhorov, BS | 1 |
| Aramaki, H; Ishiwata, K; Okamoto, M; Shimizu, I; Toyohara, J; Zaitsu, Y | 1 |
| Allen, LB; Anderson, A; Genaro-Mattos, TC; Korade, Z; Mirnics, K; Porter, NA | 1 |
| Abe, R; Hasegawa, A; Hayashi, R; Shimomura, Y; Shinkuma, S | 1 |
3 review(s) available for verapamil and emopamil
| Article | Year |
|---|---|
Calcium antagonists in the treatment of experimental cerebral ischemia.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Humans; Verapamil | 1991 |
The Ca2+ channel and 5-HT2 receptor antagonist (s)-emopamil in cerebral ischaemia.
Topics: Brain Ischemia; Calcium Channel Blockers; Humans; Serotonin Antagonists; Verapamil | 1989 |
Calcium antagonists: their role in neuroprotection.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Calcium Channels; Cerebrovascular Disorders; Dihydropyridines; Flunarizine; Humans; Neuroprotective Agents; Verapamil | 1997 |
45 other study(ies) available for verapamil and emopamil
| Article | Year |
|---|---|
Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Biological Transport; Calcium Channel Blockers; Cell Line; Dihydropyridines; Drug Resistance; Haplorhini; Immunoblotting; Membrane Glycoproteins; Mice; RNA, Messenger; Stereoisomerism; Verapamil; Vinblastine | 1992 |
Evaluation of a novel calcium channel blocker, (S)-emopamil, on regional cerebral edema and neurobehavioral function after experimental brain injury.
Topics: Animals; Blood Pressure; Brain Edema; Brain Injuries; Calcium Channel Blockers; Male; Memory; Psychomotor Performance; Rats; Rats, Inbred Strains; Reaction Time; Verapamil | 1992 |
Effects of levemopamil on neurologic and histologic outcome after cardiac arrest in cats.
Topics: Animals; Blood Gas Analysis; Brain Ischemia; Cardiopulmonary Resuscitation; Cats; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Heart Arrest; Hemodynamics; Hippocampus; Infusions, Intravenous; Male; Neurologic Examination; Severity of Illness Index; Treatment Outcome; Verapamil | 1992 |
Novel sites for phenylalkylamines: characterisation of a sodium-sensitive drug receptor with (-)-[3H]emopamil.
Topics: Animals; Binding Sites; Cations; Cerebral Cortex; Dihydropyridines; Guinea Pigs; Liver; Male; Receptors, Drug; Tissue Distribution; Tritium; Verapamil | 1991 |
Postischemic (S)-emopamil therapy ameliorates focal ischemic brain injury in rats.
Topics: Animals; Blood Pressure; Brain; Cerebral Arteries; Cerebral Infarction; Ischemic Attack, Transient; Male; Rats; Rats, Inbred Strains; Reference Values; Verapamil | 1991 |
S-emopamil ameliorates ischemic brain damage in rats: histological and behavioural approaches.
Topics: Animals; Behavior, Animal; Brain; Cerebral Cortex; Hippocampus; Ischemic Attack, Transient; Learning; Male; Necrosis; Neurons; Rats; Rats, Inbred Strains; Swimming; Verapamil | 1990 |
(S)-emopamil protects against global ischemic brain injury in rats.
Topics: Animals; Blood Pressure; Brain; Brain Ischemia; Cell Count; Cerebral Cortex; Hippocampus; Male; Neurons; Rats; Rats, Inbred Strains; Verapamil | 1990 |
Effects of phenylalkylamine calcium entry blockers on postischemic energy metabolism in the isolated perfused rat brain: stereoselective action of emopamil.
Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Energy Metabolism; Gallopamil; In Vitro Techniques; Ion Channels; Male; Perfusion; Rats; Rats, Inbred Strains; Stereoisomerism; Verapamil | 1988 |
Treatment of focal ischemia.
Topics: Animals; Brain Ischemia; Rats; Rats, Inbred Strains; Species Specificity; Verapamil | 1989 |
(S)-emopamil, a novel calcium and serotonin antagonist for the treatment of cerebrovascular disorders. 1st communication: pharmacological profile.
Topics: Animals; Binding, Competitive; Calcium Channel Blockers; Cerebrovascular Disorders; Female; Guinea Pigs; In Vitro Techniques; Ischemic Attack, Transient; Ketanserin; Male; Membranes; Mice; Muscle, Smooth, Vascular; Muscles; Myocardial Contraction; Rats; Rats, Inbred Strains; Serotonin Antagonists; Verapamil | 1989 |
(S)-emopamil, a novel calcium and serotonin antagonist for the treatment of cerebrovascular disorders. 2nd communication: brain penetration, cerebral vascular and metabolic effects.
Topics: Animals; Brain Chemistry; Calcium Channel Blockers; Cerebrovascular Circulation; Glucose; Male; Rats; Rats, Inbred Strains; Serotonin Antagonists; Verapamil | 1989 |
(S)-emopamil, a novel calcium and serotonin antagonist for the treatment of cerebrovascular disorders. 3rd communication: effect on postischemic cerebral blood flow and metabolism, and ischemic neuronal cell death.
Topics: Animals; Brain Chemistry; Brain Ischemia; Calcium Channel Blockers; Cell Survival; Cerebrovascular Circulation; Gerbillinae; Glucose; Hippocampus; Male; Neurons; Rats; Rats, Inbred Strains; Serotonin Antagonists; Verapamil | 1989 |
The effect of calcium entry blocker S-emopamil on cerebrocortical metabolism and blood flow changes evoked by graded hypotension.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cats; Cerebral Cortex; Cerebrovascular Circulation; Female; Hypotension; Male; NAD; Oxidation-Reduction; Reference Values; Regional Blood Flow; Spectrometry, Fluorescence; Verapamil | 1989 |
Effect of emopamil on cerebrocortical microcirculation during hypoxia and reactive hyperemia and on [K+]e, pH, pO2 changes during and after N2 anoxia.
Topics: Animals; Calcium Channel Blockers; Cats; Cerebral Cortex; Hydrogen-Ion Concentration; Hyperemia; Hypoxia; Microcirculation; Nitrogen; Oxygen; Partial Pressure; Potassium; Reference Values; Regional Blood Flow; Verapamil | 1989 |
(S)-emopamil, a novel calcium channel blocker and serotonin S2 antagonist, markedly reduces infarct size following middle cerebral artery occlusion in the rat.
Topics: Animals; Calcium Channel Blockers; Cerebral Arteries; Cerebral Infarction; Male; Rats; Rats, Inbred Strains; Serotonin Antagonists; Verapamil | 1988 |
The protective effect of (-) Emopamil on renal function following warm and cold ischemia.
Topics: Animals; Cold Temperature; Hot Temperature; Ischemia; Kidney; Male; Perfusion; Rats; Rats, Inbred Strains; Vasodilation; Verapamil | 1987 |
Effects of cerebroprotective agents on cerebral blood flow and on postischemic energy metabolism in the rat brain.
Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Cerebrovascular Circulation; Energy Metabolism; Furans; Ketamine; Male; Nafronyl; Nimodipine; Rats; Rats, Inbred Strains; Verapamil | 1987 |
Effects of calcium entry blocker emopamil on postischemic energy metabolism of the isolated perfused rat brain.
Topics: Animals; Brain; Brain Ischemia; Electroencephalography; Energy Metabolism; In Vitro Techniques; Male; Perfusion; Rats; Rats, Inbred Strains; Verapamil | 1987 |
Studies in phlebitis. VII: In vitro and in vivo evaluation of pH-solubilized levemopamil.
Topics: Animals; Buffers; Calcium Channel Blockers; Disease Models, Animal; Hydrogen-Ion Concentration; In Vitro Techniques; Mathematics; Models, Statistical; Pharmaceutical Preparations; Phlebitis; Rabbits; Time Factors; Verapamil | 1995 |
Phenylalkylamine Ca2+ antagonist binding protein. Molecular cloning, tissue distribution, and heterologous expression.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Calcium Channel Blockers; Carrier Proteins; Cloning, Molecular; DNA Primers; Gene Expression; Gene Library; Guinea Pigs; Humans; Kinetics; Liver; Microsomes, Liver; Molecular Sequence Data; Organ Specificity; Polymerase Chain Reaction; Protein Structure, Secondary; Recombinant Proteins; Saccharomyces cerevisiae; Sequence Homology, Amino Acid; Steroid Isomerases; Verapamil | 1995 |
Differential inhibition of neuronal calcium entry and [3H]-D-aspartate release by the quaternary derivatives of verapamil and emopamil.
Topics: Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Electrophysiology; Hippocampus; In Vitro Techniques; Neurons; Potassium; Rats; Synaptosomes; Verapamil | 1994 |
Levemopamil injection after cerebral oligemia reduces spatial memory deficits in rats.
Topics: Acetylcholine; Animals; Brain Chemistry; Calcium Channel Blockers; Carotid Arteries; gamma-Aminobutyric Acid; Ischemic Attack, Transient; Male; Maze Learning; Memory Disorders; Rats; Rats, Wistar; Serotonin Antagonists; Space Perception; Verapamil | 1994 |
Magnetic resonance imaging study on the effect of levemopamil on the size of intracerebral hemorrhage in rats.
Topics: Animals; Brain; Calcium Channel Blockers; Caudate Nucleus; Cerebral Hemorrhage; Cerebrovascular Circulation; Collagenases; Heparin; Infusions, Parenteral; Magnetic Resonance Imaging; Male; Putamen; Rats; Rats, Sprague-Dawley; Stereotaxic Techniques; Verapamil | 1994 |
(S)-emopamil reduces brain edema from collagenase-induced hemorrhage in rats.
Topics: Animals; Body Water; Brain Chemistry; Brain Edema; Calcium Channel Blockers; Cerebral Hemorrhage; Collagenases; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Necrosis; Potassium; Rats; Rats, Sprague-Dawley; Sodium; Time Factors; Verapamil | 1994 |
Effect of S-emopamil, nimodipine, and mild hypothermia on hippocampal glutamate concentrations after repeated cerebral ischemia in rabbits.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Glutamates; Glutamic Acid; Hippocampus; Hypothermia; Nimodipine; Osmolar Concentration; Rabbits; Recurrence; Verapamil | 1993 |
(S)-emopamil attenuates acute reduction in regional cerebral blood flow following experimental brain injury.
Topics: Animals; Brain Injuries; Brain Stem; Calcium Channel Blockers; Cerebellum; Cerebrovascular Circulation; Male; Rats; Rats, Sprague-Dawley; Thalamus; Verapamil | 1994 |
Oedema reduction by levemopamil in focal cerebral ischaemia of spontaneously hypertensive rats studied by magnetic resonance imaging.
Topics: Animals; Body Temperature; Brain Edema; Calcium Channel Blockers; Cerebral Infarction; Dose-Response Relationship, Drug; Histocytochemistry; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Rats; Rats, Inbred SHR; Verapamil | 1994 |
Reduction of spontaneous alcohol drinking and physical withdrawal by levemopamil, a novel Ca2+ channel antagonist, in rats.
Topics: Alcohol Drinking; Animals; Biogenic Monoamines; Brain Chemistry; Calcium Channel Blockers; Dose-Response Relationship, Drug; Eating; Ethanol; Male; Rats; Rats, Wistar; Substance Withdrawal Syndrome; Verapamil | 1993 |
Combined therapy with dizocilpine and levemopamil does not reduce ischemic neuronal injury in rats.
Topics: Animals; Calcium Channel Blockers; Dizocilpine Maleate; Drug Therapy, Combination; Ischemia; Male; Neurons; Rats; Rats, Inbred WKY; Verapamil | 1993 |
Biochemical characterization of a 22-kDa high affinity antiischemic drug-binding polypeptide in the endoplasmic reticulum of guinea pig liver: potential common target for antiischemic drug action.
Topics: Affinity Labels; Animals; Binding Sites; Binding, Competitive; Endoplasmic Reticulum; Female; Guinea Pigs; In Vitro Techniques; Ischemia; Liver; Male; Membrane Proteins; Molecular Weight; Photochemistry; Radioligand Assay; Receptors, sigma; Solubility; Verapamil | 1993 |
Diffusion- and T2-weighted imaging: evaluation of oedema reduction in focal cerebral ischaemia by the calcium and serotonin antagonist levemopamil.
Topics: Animals; Brain; Brain Edema; Calcium Channel Blockers; Ischemic Attack, Transient; Magnetic Resonance Imaging; Male; Rats; Rats, Inbred SHR; Serotonin Antagonists; Verapamil | 1993 |
Failure of levemopamil to improve histological outcome following temporary occlusion of the middle cerebral artery in cats.
Topics: Animals; Brain; Brain Ischemia; Calcium Channel Blockers; Cats; Cerebral Arteries; Cerebral Infarction; Electroencephalography; Male; Reperfusion Injury; Verapamil | 1995 |
Effect of amiloride and emopamil on intracranial pressure.
Topics: Amiloride; Animals; Brain Edema; Calcium Channel Blockers; Diuretics; Intracranial Pressure; Male; Rats; Rats, Wistar; Verapamil | 1995 |
Transfer of L-type calcium channel IVS6 segment increases phenylalkylamine sensitivity of alpha1A.
Topics: Amino Acid Sequence; Animals; Calcium Channel Blockers; Calcium Channels; Gallopamil; Molecular Sequence Data; Rabbits; Structure-Activity Relationship; Verapamil; Xenopus laevis | 1996 |
Calcium entry and 5-HT2 receptor blockade in oliguric ischaemic acute renal failure: effects of levemopamil in conscious rats.
Topics: Acute Kidney Injury; Animals; Calcium; Calcium Channel Blockers; Female; Kidney; Kidney Function Tests; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Verapamil | 1996 |
High affinity of sigma 1-binding sites for sterol isomerization inhibitors: evidence for a pharmacological relationship with the yeast sterol C8-C7 isomerase.
Topics: Animals; Binding Sites; Brain; Calcium Channel Blockers; Clomiphene; Estrogen Antagonists; Excitatory Amino Acid Antagonists; Fertility Agents, Female; Fungicides, Industrial; Guinea Pigs; Hypolipidemic Agents; Isoquinolines; Isotope Labeling; Microsomes; Microsomes, Liver; Morpholines; Pentazocine; Piperidines; Receptors, sigma; Saccharomyces cerevisiae; Stereoisomerism; Steroid Isomerases; Tamoxifen; trans-1,4-Bis(2-chlorobenzaminomethyl)cyclohexane Dihydrochloride; Triparanol; Verapamil | 1997 |
Global ischemic neuronal damage relates to behavioural deficits: a pharmacological approach.
Topics: Animals; Antioxidants; Ascorbic Acid; Behavior, Animal; Brain Ischemia; Calcium Channel Blockers; Dextromethorphan; Male; Maze Learning; Memory; Neurons; Neuroprotective Agents; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Verapamil; Vitamin E | 1998 |
Both the immunosuppressant SR31747 and the antiestrogen tamoxifen bind to an emopamil-insensitive site of mammalian Delta8-Delta7 sterol isomerase.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Cell Culture Techniques; Cyclohexanes; Estrogen Antagonists; Humans; Immunosuppressive Agents; Mice; Saccharomyces cerevisiae; Steroid Isomerases; Tamoxifen; Transformation, Genetic; Verapamil | 1998 |
Effect of hydroxypropyl-beta-cyclodextrin and pH on the solubility of levemopamil HCl.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; beta-Cyclodextrins; Calcium Channel Blockers; Cyclodextrins; Drug Stability; Hydrogen-Ion Concentration; Molecular Structure; Solubility; Verapamil | 1998 |
Practical synthesis of chiral emopamil left hand as a bioactive motif.
Topics: Catalysis; Chemistry, Organic; Chromatography, High Pressure Liquid; Magnetic Resonance Spectroscopy; Molecular Structure; Organometallic Compounds; Stereoisomerism; Verapamil | 2002 |
Discovery of novel neuronal voltage-dependent calcium channel blockers based on emopamil left hand as a bioactive template.
Topics: Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Combinatorial Chemistry Techniques; Ion Channel Gating; Piperazines; Rats; Solubility; Stereoisomerism; Structure-Activity Relationship; Synaptosomes; Verapamil | 2003 |
Why does the inner-helix mutation A413C double the stoichiometry of Kv1.3 channel block by emopamil but not by verapamil?
Topics: Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Chlorocebus aethiops; COS Cells; Cysteine; Humans; Hydrogen Bonding; Kv1.3 Potassium Channel; Molecular Sequence Data; Mutation; Potassium Channel Blockers; Protein Structure, Secondary; Stereoisomerism; Verapamil | 2011 |
(R)-[¹¹C]Emopamil as a novel tracer for imaging enhanced P-glycoprotein function.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Brain; Carbon Radioisotopes; Cyclosporine; Male; Mice; Positron-Emission Tomography; Rats; Stereoisomerism; Tissue Distribution; Verapamil | 2016 |
Amiodarone Alters Cholesterol Biosynthesis through Tissue-Dependent Inhibition of Emopamil Binding Protein and Dehydrocholesterol Reductase 24.
Topics: Amiodarone; Carrier Proteins; Cholesterol; Dehydrocholesterols; Desmosterol; Humans; Nerve Tissue Proteins; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Verapamil | 2020 |
Pustular Skin Lesions in an Adult Female Patient with X-linked Dominant Chondrodysplasia Punctata with a Novel Emopamil Binding Protein Mutation: A Rare Skin Manifestation.
Topics: Adult; Carrier Proteins; Chondrodysplasia Punctata; Female; Genes, Dominant; Humans; Mutation; Verapamil | 2021 |