verapamil has been researched along with dihydropyridines in 187 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 40 (21.39) | 18.7374 |
| 1990's | 112 (59.89) | 18.2507 |
| 2000's | 27 (14.44) | 29.6817 |
| 2010's | 8 (4.28) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Araie, E; Miwa, K; Miyagi, Y; Sasayama, S | 1 |
| Howlett, SE; Nicholl, PA | 1 |
| Zernig, G | 1 |
| Böck, G; Drach, J; Grunicke, H; Hofmann, J; Ludescher, C; Spitaler, M; Wolf, A | 1 |
| Naito, M; Tsuruo, T | 1 |
| Dietel, M; Höllt, V; Kouba, M; Vogt, G | 1 |
| Charuk, JH; Reithmeier, RA | 1 |
| Bruggemann, EP; Currier, SJ; Gottesman, MM; Pastan, I | 1 |
| Anstett, M; Atassi, G; Bizzari, JP; Genton, A; Léonce, S; Pérez, V; Pierré, A | 1 |
| Hallaq, H; Leaf, A; Smith, TW | 1 |
| Colombo, G; Fadda, F; Garau, B; Gessa, GL | 1 |
| Benterbusch, R; Herberg, FW; Melzer, W; Thieleczek, R | 1 |
| Mason, RP; Moisey, DM; Shajenko, L | 1 |
| Larochelle, P | 1 |
| Findlay, JD; Pullar, IA | 1 |
| Lipton, SA | 1 |
| McCarty, NA; O'Neil, RG | 1 |
| Gottesman, MM; Horio, M; Lovelace, E; Pastan, I | 1 |
| Suzuki, H; Tatsuta, T; Tomida, A | 1 |
| Fukazawa, N; Sato, W; Suzuki, T; Tsuruo, T; Yusa, K | 1 |
| Maeda, H; Miyamoto, Y | 1 |
| Naitoh, T; Sugimoto, T; Toyo-Oka, T | 1 |
| Brocklehurst, KW; Ceña, V; Pollard, HB; Rojas, E | 1 |
| Rampe, D; Triggle, DJ; Zheng, W | 1 |
| Gambini, F; Gaviraghi, G; Micheli, D; Quartaroli, M; Tarter, G; Trist, DG | 1 |
| Höschl, C | 1 |
| Memo, M; Pizzi, M; Ribola, M; Spano, P; Valerio, A | 1 |
| Orloff, M; Reznik, GK; Schüller, HM | 1 |
| Glossmann, H; Mühlbacher, J; Staudinger, R; Zech, C | 1 |
| Dong, H; Lu, YQ; Wang, Q; Yang, QQ; Yang, ZC | 1 |
| Bittar, EE; Nwoga, J | 1 |
| Zlotogorski, A | 1 |
| Akiyama, S; Douzono, H; Ikeda, S; Nagata, Y; Sugita, M; Sumizawa, T; Yoshimura, A | 1 |
| Gindin, E; Greenberger, LM; Horwitz, SB; Yang, CP | 1 |
| Bindslev, N; Demant, EJ; Friche, E; Jensen, PB; Sehested, M; Skovsgaard, T | 1 |
| Demant, EJ; Friche, E; Jensen, PB; Nissen, NN; Sehested, M | 1 |
| Thulin, T | 1 |
| Glossmann, H; Knaus, HG; Romanin, C; Scheffauer, F; Schindler, HG | 1 |
| Gordon, T; Howlett, SE | 1 |
| Bauer, JH; Reams, GP | 1 |
| Hosey, MM; McMahon, KK; Ptasienski, J | 1 |
| Ferry, DR; Glossmann, H; Goll, A; Schober, M; Striessnig, J | 1 |
| Creba, JA; Karobath, M | 1 |
| Glossmann, H; Goll, A; Moosburger, K; Striessnig, J | 1 |
| Challoner-Hue, L; Steele, TH | 1 |
| Hofmann, F; Nastainczyk, W; Sieber, M; Wernet, W; Zubor, V | 1 |
| Florio, T; Grimaldi, M; Landolfi, E; Magri, G; Meucci, O; Schettini, G; Yasumoto, T | 1 |
| Glossmann, H; Hymel, L; Schindler, H; Striessnig, J | 1 |
| Dunn, SM | 2 |
| Pan, M; Scriabine, A | 1 |
| Chiu, M; Dionne, MA; Marsh, JD; Smith, TW | 1 |
| Dillon, JS; Gu, XH; Nayler, WG | 1 |
| Dutton, GR; Philibert, RA | 1 |
| Flockerzi, V | 1 |
| Chartrand, C; Dumont, L; Kangha, M; Lord, C | 1 |
| Hudecová, S; Krizanová, O; Orlický, J; Zachar, J | 1 |
| Arceci, RJ; DePinho, SG; Greenberger, LM; Horwitz, SB; Yang, CP | 1 |
| Kuriyama, H; Oike, M; Xiong, ZL | 1 |
| Safa, AR; Spearman, T; Van Dyke, K; Ye, ZG | 1 |
| Wallis, DE | 1 |
| Bacon, KB; Camp, RD; Westwick, J | 1 |
| Glossmann, H; Knaus, HG; Striessnig, J | 1 |
| Garcia, L; Lazdunski, M; Rieger, F; Romey, G | 1 |
| Florio, T; Grimaldi, M; Landolfi, E; Magri, G; Meucci, O; Schettini, G | 1 |
| Barhanin, J; Henning, R; Lazdunski, M; Lerch, U; Oekonomopulos, R; Qar, J; Romey, G; Urbach, H | 1 |
| Reynolds, IJ; Snowman, AM; Snyder, SH | 1 |
| Lessem, JN | 1 |
| Barlier, S; Colin, DA; Couraud, F; Dayanithi, G; Kretz-Zaepfel, M; Martin-Moutot, N; Nordmann, JJ | 1 |
| Corvol, P; Jeunemaitre, X; Julien, J; Pagny, JY; Plouin, PF | 1 |
| Glossmann, H; Zernig, G | 1 |
| Ortega, MP; Priego, JG; Statkow, PR; Sunkel, C | 1 |
| Bolger, GT; Crawley, JN; Paul, SM; Rafferty, MF; Skolnick, P | 1 |
| Giacomini, JC; Giacomini, KM; Nelson, WL; Zobrist, RH | 1 |
| Cavero, I; Spedding, M | 1 |
| Kass, RS; Sanguinetti, MC | 1 |
| Ferry, DR; Gadow, C; Glossmann, H; Goll, A | 1 |
| Kostiuk, PG | 1 |
| Heaslip, RJ; Rahwan, RG | 1 |
| Hiwatari, M; Imai, Y; Taira, N | 1 |
| Boiocchi, M; Cappelletto, B; Corona, G; Gigante, M; Raschack, M; Simone, F; Toffoli, G | 1 |
| Akiyama, Y; Morinaga, Y; Nakagawa, R; Ohishi, K; Ohsumi, K; Sekiyama, T; Suga, Y; Tsuji, T; Tsuruo, T | 1 |
| Bennis, S; Ichas, F; Robert, J | 1 |
| Eliason, JF; Ishikawa, T; Ramuz, H; Tsuruo, T; Yamamoto, T; Yoshikubo, T | 1 |
| Abe, T; Hidaka, K; Kohno, K; Koike, K; Kubo, T; Kuwano, M; Mori, T; Ohga, T; Wada, M | 1 |
| Gielow, ML; Gu, GG; Singh, S | 1 |
| Satoh, H; Tsuchida, K | 1 |
| Bates, SE; Dickstein, B; Fojo, AT; Lee, JS; Spolyar, M | 1 |
| Bülow, A; Johansson, B | 1 |
| Ashbourne, KJ; DiDiodato, G; Sharom, FJ; Yu, X | 1 |
| Reams, GP | 1 |
| Senior, AE; Urbatsch, IL | 1 |
| Franceschini, G; Sirtori, CR | 1 |
| Koseki, Y; Lothstein, L; Sweatman, TW | 1 |
| Georges, E; Ling, V; Liu, Z; Zordan-Nudo, T | 1 |
| Kang, Y; Perry, RR | 1 |
| Gajdzik, L; Graf, J; Stapf, V; Thalhammer, T | 1 |
| Locher, R; Lupo, E; Vetter, W; Weisser, B | 1 |
| Elias, PM; Feingold, KR; Lee, SH; Mauro, T | 1 |
| Abrosimov, IIu; Karpova, MN; Kryzhanovskiĭ, GN; Lakinina, MV; Pankov, OIu | 1 |
| Abraham, I; Sampson, KE; Wolf, CL | 1 |
| Eichelbaum, M; Klumpp, B; Krause, J; Roller, E; Schumacher, K | 1 |
| Bocciolone, M; Boselli, L; Comerio, G; Cuspidi, C; Leonetti, G; Lonati, L; Sampieri, L; Zanchetti, A | 1 |
| Lombet, A; Spedding, M | 1 |
| Salerno, SM; Zugibe, FT | 1 |
| Hill, BT; Hosking, LK | 1 |
| Karasawa, A; Kubo, K; Shirakura, S | 1 |
| Boksa, P; Quirion, R; Sen, AP | 1 |
| Chen, Y; Fukuo, K; Jiang, B; Kimura, T; Kitano, S; Koh, E; Morimoto, S; Ogihara, T; Sakakibara, S; Yasuda, O | 1 |
| Berger, W; Friedrich, K; Garcia, ML; Glossmann, H; Goetz, MA; Hering, S; Kaczorowski, GJ; Liesch, JM; Savchenko, A; Zink, DL | 1 |
| Badr, KF; Fukunaga, M; Katoh, T; Takahashi, K | 1 |
| Agrotis, A; Bobik, A; Little, PJ; Saltis, J | 1 |
| Dietel, M; Erttmann, R; Looft, G; Reymann, A; Woermann, C | 1 |
| Frewin, D; Tonkin, A | 1 |
| Miranda, HF; Pelissier, T; Sierralta, F | 1 |
| Pfaffendorf, M; van Zwieten, PA | 1 |
| Carson, CC; Hagen, PO; Kerfoot, WW; Park, HY; Schwartz, LB | 1 |
| Eisterer, W; Hilbe, W; Hofmann, J; Ludescher, C; Thaler, J | 1 |
| Baldy-Moulinier, M; Diochot, S; Nargeot, J; Richard, S; Valmier, J | 1 |
| Block, LH; Eickelberg, O; Erne, P; Kohler, E; Roth, M | 1 |
| Masumiya, H; Saito, W; Sekine, T; Shigenobu, K; Sijuku, T; Sugahara, M; Tanaka, H; Taniguchi, H; Terada, M | 1 |
| Katina, IE; Lukyanenko, V; Nasledov, GA; Terentyev, DA | 1 |
| Bamberger, U; Georges, E; Heckel, A; Lheureux, F; Liu, Z; Pouliot, JF | 1 |
| Boer, R; Gekeler, V; Grunicke, H; Hofmann, J; Ise, W; Klemm, K; Sanders, KH; Schächtele, C; Schubert, C; Uberall, F; Utz, I | 1 |
| Held, C; Laragh, JH; Messerli, F; Pepine, C; Sleight, P | 1 |
| Kuniyasu, A; Nakayama, H | 1 |
| Dei Cas, L; Fappani, A; Metra, M; Nodari, S; Pelá, G; Raddino, R | 1 |
| Kikuchi, K; Sugawara, H; Tobise, K | 1 |
| Hunter, AJ | 1 |
| Katoch, SS; Pfitzer, G; Rüegg, JC | 1 |
| Chapey, C; Hu, YP; Robert, J | 1 |
| Chen, G; Dumontet, C; Durán, GE; Jaffrézou, JP; Lacayo, NJ; Sikic, BI; Steger, KA | 1 |
| Abu Khoudoud, OR; Bikhazi, AB; Bitar, KM; el-Kasti, MM; Ibrahim, MZ; Kreydiyyeh, SI; Saleh, RS | 1 |
| Barakat, L; Boquet, G; Djiane, J; Dufy, B; Paly, J | 1 |
| Dickstein, K; Gundersen, T; Hole, T; Kjekshus, J; Myhre, ES; Rønnevik, PK; Westheim, AS | 1 |
| Grossman, E; Messerli, FH | 1 |
| Bossi, M; Tiberti, G | 1 |
| Boss, H; Dietel, M; Pest, S; Reymann, A; Seidel, A | 1 |
| Bollo-Dragnic, S; Díaz-Araya, G; Letelier, ME; Marín-Catalán, R; Núñez-Vergara, LJ; Pino, L; Squella, JA | 1 |
| Conlin, PR; Williams, GH | 1 |
| Haraguchi, K; Iga, T; Ito, K; Kotaki, H; Sawada, Y | 1 |
| Antonios, TF; MacGregor, GA | 1 |
| Garrigos, M; Orlowski, S; Pascaud, C | 1 |
| Kanaya, N; Kawana, S; Kimura, H; Matsumoto, M; Miyamoto, A; Namiki, A; Ohshika, H; Tsuchida, H | 1 |
| Beck, JF; Boer, R; Buchholz, F; Gekeler, V; Niethammer, D; Sanders, KH; Ulrich, WR | 1 |
| Atchison, WD; Hewett, SJ; Xu, YF | 1 |
| Gieseler, F; Gullis, E; Hasmann, M; Löser, R; Nüssler, V; Pelka-Fleisc, R; Stötzer, O; Wilmanns, W; Zwierzina, H | 1 |
| Gao, X; Gillman, MW; Goldman, L; Hertzmark, E; McLaughlin, TJ; Ross-Degnan, D; Soumerai, SB; Spiegelman, D | 1 |
| An, RH; Hofmann, F; Ito, H; Kass, RS; Klugbauer, N; Lacinová, L; Triggle, D; Xia, J | 1 |
| García, AG; García-Palomero, E; Herrero, CJ; Montiel, C; Pintado, AJ | 1 |
| Kasimir-Bauer, S; Scheulen, ME; Schröder, JK; Seeber, S | 1 |
| Chen, KG; Cohen, D; Durán, GE; Lacayo, NJ; Sikic, BI | 1 |
| Hayashi, M; Nakazato, Y; Saruta, T; Yamaji, Y | 1 |
| Fujita, R; Ishikawa, M; Sasaki, K; Takayanagi, M; Takayanagi, Y | 1 |
| Dressler, C; Hilgeroth, A; Langguth, P; Neuhoff, S; Spahn-Langguth, H | 1 |
| Lévy, S | 1 |
| García-Barrado, MJ; Iglesias-Osma, MC; Moratinos, J; Sancho, C | 1 |
| Bidet, M; Martial, S; Martin, D; Melendez, E; Namorado, MD; Poujeol, C; Poujeol, P; Reyes, JL; Sanchez, E; Tauc, M; Valencia, L | 1 |
| Cathala, L; Chesnoy-Marchais, D | 1 |
| Agabiti-Rosei, E; Castellano, M; de Kam, PJ; Fallon, M; Fluckiger, L; Hausberg, M; Heitmann, J; Lefrandt, JD; Murphy, M; Rahn, KH; Rostrup, M; Sevre, K; Smit, AJ; Urbigkeit, A; van Roon, AM; Zannad, F | 1 |
| Kawase, M; Motohashi, N | 1 |
| Chao, YY; Jan, CR | 1 |
| El Bardai, S; Hamaide, MC; Lyoussi, B; Morel, N; Quetin-Leclercq, J; Wibo, M | 1 |
| Fukuda, Y; Hara, M; Kinebuchi, O; Kurita, Y; Mitamura, H; Miyoshi, S; Ogawa, S; Ohashi, N; Shiroshita-Takeshita, A; Takatsuki, S; Tanimoto, K | 1 |
| Hoda, JC; Huber, IG; Sinnegger-Brauns, MJ; Striessnig, J; Walter-Bastl, D; Wappl-Kornherr, E | 1 |
| Handler, J | 1 |
| Logan, A | 1 |
| Sica, D | 1 |
| Amini, M; Azizi, E; Bazargan, L; Fouladdel, S; Ghaffari, SM; Shafiee, A | 1 |
| Holstege, C; Winchester, DE | 1 |
| Berenshteĭn, NV; Burmistrova, LF; Iskenderov, BG; Lokhina, TV | 1 |
| Perez-Reyes, E; Van Deusen, AL; Vitko, I | 1 |
| Masai, H; Miwa, Y; Shimizu, M | 1 |
| Ball, CJ; Beltrame, JF; Saint, DA; Turner, SP; Wilson, DP | 1 |
| Engi, H | 1 |
| Godfraind, T | 1 |
| Cheng, RCK; Tikhonov, DB; Zhorov, BS | 1 |
| Ikeda, K; Saito, T; Tojo, K | 1 |
| Bergmann, I; Deters, M; Enden, G; Hentschel, H; Kutz, S; Liebetrau, G; Plenert, B; Prasa, D | 1 |
| Chattipakorn, N; Chattipakorn, S; Chinda, K; Fucharoen, S; Kumfu, S | 1 |
| Chattipakorn, N; Chattipakorn, S; Fucharoen, S; Kumfu, S | 1 |
| Bilbault, P; Gourieux, B; Lambert Kuhn, E; Levêque, D; Lioure, B | 1 |
| Catterall, WA; Gamal El-Din, TM; Pryde, DC; Scheuer, T; Swanson, TM; Tang, L; Zheng, N | 1 |
| Canbolat, S; Nurullahoglu Atalik, KE | 1 |
| Aimoto, M; Cao, X; Ishiguro, A; Nagasawa, Y; Nozaki, S; Okamura, K; Takahara, A | 1 |
19 review(s) available for verapamil and dihydropyridines
| Article | Year |
|---|---|
Renal tubular effects of calcium antagonists.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Diuresis; Humans; Kidney Tubules; Natriuresis; Verapamil | 1992 |
Do calcium antagonists have a place in the treatment of mood disorders?
Topics: Affective Disorders, Psychotic; Bipolar Disorder; Calcium; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Mood Disorders; Neurons; Premenstrual Syndrome; Psychotropic Drugs; Verapamil | 1991 |
New drugs for hypertension--variations on old themes.
Topics: Amlodipine; Antihypertensive Agents; Delayed-Action Preparations; Dihydropyridines; Doxazosin; Humans; Hypertension; Isradipine; Nifedipine; Prazosin; Verapamil | 1991 |
Calcium antagonists--assessment of side effects.
Topics: Benzodiazepines; Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Health Status; Humans; Hypertension; Quality of Life; Verapamil | 1990 |
Effects of calcium antagonists on the hypertensive kidney.
Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Humans; Hypertension; Kidney; Kidney Function Tests; Verapamil | 1990 |
Calcium-channel blockers in the management of essential hypertension.
Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Humans; Hypertension; Verapamil | 1989 |
"Calcium antagonists": a class of drugs with a bright future. Part II. Determination of basic pharmacological properties.
Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Electrophysiology; Heart Rate; Ion Channels; Lanthanum; Methods; Muscle, Smooth; Myocardial Contraction; Nifedipine; Potassium; Pyridines; Receptors, Adrenergic, alpha; Stereoisomerism; Verapamil | 1984 |
[Calcium ion channels in the cell membrane].
Topics: Animals; Brachyura; Calcium; Cations, Divalent; Cations, Monovalent; Cattle; Decapodiformes; Dihydropyridines; Fluorides; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Mice; Mollusca; Neurons; Organ Specificity; Pyridines; Rats; Species Specificity; Verapamil | 1984 |
Do calcium channel blockers have renal protective effects?
Topics: Aging; Animals; Calcium Channel Blockers; Clinical Trials as Topic; Cyclosporine; Diabetic Nephropathies; Dihydropyridines; Diltiazem; Disease Models, Animal; Glomerular Filtration Rate; Hemodynamics; Humans; Hypertension, Renal; Kidney; Kidney Transplantation; Rats; Rats, Inbred SHR; Verapamil | 1994 |
Similarities and differences between calcium antagonists: pharmacological aspects.
Topics: Angina Pectoris; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Humans; Hypertension; Nifedipine; Vasodilator Agents; Verapamil | 1993 |
Calcium antagonists and cardiovascular prognosis: a homogeneous group?
Topics: Calcium Channel Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Humans; Prognosis; Verapamil | 1996 |
Identification of binding sites for calcium channel antagonists.
Topics: Affinity Labels; Benzazepines; Binding Sites; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Drug Interactions; Humans; Muscle, Skeletal; Thiazepines; Verapamil | 1996 |
Calcium antagonists: their role in neuroprotection.
Topics: Animals; Brain Ischemia; Calcium Channel Blockers; Calcium Channels; Cerebrovascular Disorders; Dihydropyridines; Flunarizine; Humans; Neuroprotective Agents; Verapamil | 1997 |
[Calcium channel blockers in heart failure].
Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Heart Failure; Humans; Ventricular Dysfunction, Left; Verapamil | 1997 |
Use of calcium channel blockers in hypertension.
Topics: Antihypertensive Agents; Benzimidazoles; Blood Pressure; Calcium Channel Blockers; Case-Control Studies; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Heart Diseases; Humans; Hypertension; Longitudinal Studies; Mibefradil; Nifedipine; Public Health; Randomized Controlled Trials as Topic; Risk Factors; Tetrahydronaphthalenes; Vasodilator Agents; Verapamil | 1998 |
Some similarities and differences between verapamil and the dihydropyridines.
Topics: Antihypertensive Agents; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Disease; Dihydropyridines; Drug Therapy, Combination; Humans; Hypertension; Sympathetic Nervous System; Verapamil | 1998 |
Pharmacologic management of atrial fibrillation: current therapeutic strategies.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channel Blockers; Chronic Disease; Digoxin; Dihydropyridines; Drug Administration Routes; Electrocardiography; Embolism; Heart Rate; Humans; Practice Guidelines as Topic; Prognosis; Propranolol; Secondary Prevention; Tachycardia, Paroxysmal; Verapamil | 2001 |
New multidrug resistance reversal agents.
Topics: Antineoplastic Agents; Dihydropyridines; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonoids; Humans; Phenothiazines; Plant Preparations; Propafenone; Quinolines; Verapamil | 2003 |
Calcium channel blockers and the kidney.
Topics: Black or African American; Calcium Channel Blockers; Diabetic Nephropathies; Dihydropyridines; Diltiazem; Humans; Hypertension; Kidney; Kidney Failure, Chronic; United States; Verapamil | 2004 |
5 trial(s) available for verapamil and dihydropyridines
| Article | Year |
|---|---|
Antihypertensive and humoral effects of verapamil and lacidipine in combination in hypertensive patients.
Topics: Adult; Aldosterone; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Renin; Verapamil | 1993 |
The effects of dihydropyridine and phenylalkylamine calcium antagonist classes on autonomic function in hypertension: the VAMPHYRE study.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Autonomic Nervous System; Baroreflex; Blood Pressure; Calcium Channel Blockers; Carrier Proteins; Cross-Over Studies; Dihydropyridines; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Steroid Isomerases; Treatment Outcome; Verapamil | 2001 |
BENEDICT in the treatment of hypertension.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Creatinine; Diabetes Mellitus, Type 2; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypertension; Indoles; Treatment Outcome; Verapamil | 2005 |
[Hypotensive efficacy and tolerability of combination of dihydropyridine and non-dihydropyridine calcium antagonists in the treatment of patients with arterial hypertension].
Topics: Adult; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nifedipine; Obesity; Treatment Outcome; Verapamil | 2007 |
Differential effects of calcium-channel blockers on vascular endothelial function in patients with coronary spastic angina.
Topics: Aged; Blood Pressure; Calcium Channel Blockers; Coronary Vasospasm; Dihydropyridines; Diltiazem; Endothelium, Vascular; Female; Humans; Male; Middle Aged; Vasodilation; Verapamil | 2009 |
163 other study(ies) available for verapamil and dihydropyridines
| Article | Year |
|---|---|
Effects of diltiazem and verapamil on (+)-PN 200-110 binding kinetics in dog cardiac membranes.
Topics: Allosteric Regulation; Animals; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Dogs; Female; In Vitro Techniques; Isradipine; Kinetics; Male; Myocardium; Receptors, Nicotinic; Temperature; Verapamil | 1992 |
Density of 1,4-dihydropyridine receptors decreases in the hearts of aging hamsters.
Topics: Aging; Allosteric Site; Animals; Calcium Channels; Cricetinae; Dihydropyridines; Diltiazem; In Vitro Techniques; Kinetics; Male; Myocardium; Nifedipine; Verapamil | 1992 |
Photoaffinity labeling of the partially purified mitochondrial phenylalkylamine calcium antagonist receptor.
Topics: Affinity Labels; Azides; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electrophoresis, Polyacrylamide Gel; Mitochondria; Verapamil | 1992 |
Reversal of multidrug resistance by B859-35, a metabolite of B859-35, niguldipine, verapamil and nitrendipine.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cell Division; Dihydropyridines; Drug Resistance; Humans; Membrane Glycoproteins; Nitrendipine; Rats; Rhodamines; Verapamil | 1992 |
Functionally active homodimer of P-glycoprotein in multidrug-resistant tumor cells.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dihydropyridines; Doxorubicin; Drug Resistance; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Macromolecular Substances; Membrane Glycoproteins; Mitolactol; Mitomycins; Precipitin Tests; Succinimides; Tumor Cells, Cultured; Verapamil; Vincristine | 1992 |
Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding, Competitive; Biological Transport; Calcium Channel Blockers; Cell Line; Dihydropyridines; Drug Resistance; Haplorhini; Immunoblotting; Membrane Glycoproteins; Mice; RNA, Messenger; Stereoisomerism; Verapamil; Vinblastine | 1992 |
Interaction of P-glycoprotein with a hydrophobic component of rat urine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; CHO Cells; Cricetinae; Dihydropyridines; Drug Resistance; Female; Kinetics; Male; Membrane Glycoproteins; Rats; Tissue Extracts; Urine; Verapamil; Vinblastine | 1992 |
Characterization of the azidopine and vinblastine binding site of P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Cell Line; Cell Membrane; Colchicine; Cyanogen Bromide; Dihydropyridines; Drug Resistance; Humans; KB Cells; Kinetics; Membrane Glycoproteins; Molecular Weight; Peptide Fragments; Transfection; Trypsin; Verapamil; Vinblastine; Vincristine | 1992 |
Effects of a new triazinoaminopiperidine derivative on adriamycin accumulation and retention in cells displaying P-glycoprotein-mediated multidrug resistance.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carcinoma, Squamous Cell; Cell Cycle; Cell Membrane; Cells, Cultured; Colonic Neoplasms; Cricetinae; Cricetulus; Dihydropyridines; Doxorubicin; Drug Resistance; Flow Cytometry; Fluorescence; Humans; Kinetics; Leukemia P388; Leukemia, Myeloid, Acute; Lung; Membrane Glycoproteins; Mice; Piperidines; Sensitivity and Specificity; Triazines; Tritium; Tumor Cells, Cultured; Verapamil | 1992 |
Modulation of dihydropyridine-sensitive calcium channels in heart cells by fish oil fatty acids.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channels; Cells, Cultured; Dihydropyridines; Fatty Acids, Unsaturated; Fish Oils; Heart; In Vitro Techniques; Ion Channel Gating; Myocardial Contraction; Nitrendipine; Ouabain; Rats; Verapamil | 1992 |
Isradipine and other calcium channel antagonists attenuate ethanol consumption in ethanol-preferring rats.
Topics: Alcohol Drinking; Animals; Calcium Channel Blockers; Dihydropyridines; Dose-Response Relationship, Drug; Ethanol; Isradipine; Male; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1992 |
Excitation-contraction coupling in a pre-vertebrate twitch muscle: the myotomes of Branchiostoma lanceolatum.
Topics: Animals; Blotting, Western; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cell Movement; Chordata, Nonvertebrate; Dihydropyridines; Membrane Potentials; Microsomes; Muscle Contraction; Nifedipine; Ryanodine; Verapamil | 1992 |
Cholesterol alters the binding of Ca2+ channel blockers to the membrane lipid bilayer.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cell Membrane; Cholesterol; Dihydropyridines; Diltiazem; Electrons; Isradipine; Lipid Bilayers; Myocardium; Nifedipine; Nimodipine; Nitrendipine; Phosphatidylcholines; Rabbits; Verapamil | 1992 |
Effect of voltage-sensitive calcium channel antagonists on the release of 5-hydroxytryptamine from rat hippocampus in vivo.
Topics: Animals; Calcium; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Electric Stimulation; Hippocampus; Male; Nifedipine; omega-Conotoxins; Peptides, Cyclic; Rats; Rats, Inbred Strains; Serotonin; Verapamil | 1992 |
Calcium channel antagonists and human immunodeficiency virus coat protein-mediated neuronal injury.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Survival; Cells, Cultured; Dihydropyridines; Diltiazem; Flunarizine; HIV Envelope Protein gp120; HIV-1; Peptide Fragments; Rats; Recombinant Fusion Proteins; Retinal Ganglion Cells; Verapamil | 1991 |
Calcium-dependent control of volume regulation in renal proximal tubule cells: II. Roles of dihydropyridine-sensitive and -insensitive Ca2+ entry pathways.
Topics: Animals; Biological Transport; Calcium; Calcium Channels; Cell Membrane Permeability; Dihydropyridines; Hypotonic Solutions; Ion Channel Gating; Kidney Tubules, Proximal; Microscopy, Fluorescence; Nifedipine; Rabbits; Verapamil | 1991 |
Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Biological Transport, Active; Carcinoma, Squamous Cell; Cell Membrane; Dihydropyridines; Drug Resistance; Humans; Kinetics; Leucine; Membrane Glycoproteins; Phenothiazines; Quinidine; Trifluoperazine; Tumor Cells, Cultured; Verapamil; Vinblastine | 1991 |
Novel mechanism of N-solanesyl-N,N'-bis(3,4-dimethoxybenzyl)ethylenediamine in potentiation of antitumor drug action on multidrug-resistant and sensitive Chinese hamster cells.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Membrane; Cricetinae; Cricetulus; Daunorubicin; Dihydropyridines; Doxorubicin; Drug Resistance; Drug Synergism; Ethylenediamines; Membrane Glycoproteins; Terpenes; Verapamil; Vinblastine | 1991 |
Circumvention of multidrug resistance by a newly synthesized quinoline derivative, MS-073.
Topics: Affinity Labels; Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dihydropyridines; Drug Administration Schedule; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Female; Leukemia P388; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Piperazines; Quinolines; Tumor Cells, Cultured; Verapamil; Vincristine | 1991 |
Enhancement by verapamil of neocarzinostatin action on multidrug-resistant Chinese hamster ovary cells: possible release of nonprotein chromophore in cells.
Topics: Animals; Antioxidants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Division; Cell Line; Cell Membrane; Cell Survival; Cells, Cultured; Cricetinae; Cricetulus; Dihydropyridines; Drug Resistance; Drug Synergism; Female; Kinetics; Membrane Glycoproteins; Ovary; Verapamil; Zinostatin | 1991 |
An endogenous Ca2+ channel agonist, endothelin-1, does not directly activate partially purified dihydropyridine-sensitive Ca2+ channel from cardiac muscle in a reconstituted system.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Endothelins; Heart; Isradipine; Kinetics; Liposomes; Microsomes; Oxadiazoles; Proteolipids; Sarcolemma; Swine; Verapamil | 1990 |
Pertussis toxin stimulation of catecholamine release from adrenal medullary chromaffin cells: mechanism may be by direct activation of L-type and G-type calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Cadmium; Calcium Channel Blockers; Calcium Channels; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Dihydropyridines; Electric Conductivity; Membrane Potentials; Nifedipine; Pertussis Toxin; Verapamil; Virulence Factors, Bordetella | 1991 |
Pharmacological, radioligand binding, and electrophysiological characteristics of FPL 64176, a novel nondihydropyridine Ca2+ channel activator, in cardiac and vascular preparations.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Isradipine; Male; Myocardium; Potassium; Pyrroles; Radioligand Assay; Rats; Vasoconstriction; Verapamil | 1991 |
The hemodynamic effects of lacidipine in anesthetized dogs: comparison with nitrendipine, amlodipine, verapamil, and diltiazem.
Topics: Amlodipine; Anesthesia; Animals; Blood Gas Analysis; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Diltiazem; Dogs; Dose-Response Relationship, Drug; Electrocardiography; Heart Rate; Hemodynamics; Male; Myocardial Contraction; Nifedipine; Nitrendipine; Stroke Volume; Vascular Resistance; Verapamil | 1991 |
Various Ca2+ entry blockers prevent glutamate-induced neurotoxicity.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Animals, Newborn; Calcium Channel Blockers; Cerebellum; Dihydropyridines; Excitatory Amino Acid Antagonists; Glutamates; Glutamic Acid; Ibotenic Acid; Isradipine; Kainic Acid; Nerve Degeneration; Nervous System Diseases; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1991 |
Antiproliferative effects of the Ca2+/calmodulin antagonist B859-35 and the Ca(2+)-channel blocker verapamil on human lung cancer cell lines.
Topics: Adenocarcinoma; Antineoplastic Agents; Calcium Channel Blockers; Carcinoid Tumor; Cell Division; Dihydropyridines; Humans; Lung Neoplasms; Tumor Cells, Cultured; Verapamil | 1991 |
Novel sites for phenylalkylamines: characterisation of a sodium-sensitive drug receptor with (-)-[3H]emopamil.
Topics: Animals; Binding Sites; Cations; Cerebral Cortex; Dihydropyridines; Guinea Pigs; Liver; Male; Receptors, Drug; Tissue Distribution; Tritium; Verapamil | 1991 |
Antagonistic effects of dihydropyridines and verapamil on CaCl2 and 5-HT-evoked contraction in porcine coronary artery.
Topics: Animals; Calcium Chloride; Coronary Vessels; Dihydropyridines; Felodipine; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Nifedipine; Nimodipine; Serotonin Antagonists; Swine; Verapamil | 1991 |
An investigation of the sensitivity of the ouabain-insensitive sodium efflux in single barnacle muscle fibers to pentachlorophenol.
Topics: Animals; Cadmium; Calcium; Calcium Channel Blockers; Cobalt; Cytosol; Dihydropyridines; Egtazic Acid; Gallic Acid; Hydrogen-Ion Concentration; Kinetics; Muscles; Osmolar Concentration; Ouabain; Pentachlorophenol; Ryanodine; Sodium; Stimulation, Chemical; Thoracica; Verapamil | 1991 |
Calcium blockers and gingival hyperplasia.
Topics: Calcium Channel Blockers; Dihydropyridines; Gingival Hyperplasia; Humans; Verapamil | 1991 |
Aspergillus species strain M39 produces two naphtho-gamma-pyrones that reverse drug resistance in human KB cells.
Topics: Aspergillus; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Chemical Phenomena; Chemistry; Dihydropyridines; Doxorubicin; Drug Resistance; Humans; Membrane Glycoproteins; Naphthols; Pyrans; Pyrones; Verapamil; Vinblastine | 1990 |
Photoaffinity probes for the alpha 1-adrenergic receptor and the calcium channel bind to a common domain in P-glycoprotein.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Binding, Competitive; Calcium Channels; Cell Line; Cell Membrane; Chymotrypsin; Dihydropyridines; Drug Resistance; Macrophages; Membrane Glycoproteins; Mice; Peptide Mapping; Prazosin; Receptors, Adrenergic, alpha; Sequence Homology, Nucleic Acid; Verapamil | 1990 |
Transport of the multidrug resistance modulators verapamil and azidopine in wild type and daunorubicin resistant Ehrlich ascites tumour cells.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carcinoma, Ehrlich Tumor; Cells, Cultured; Daunorubicin; Dihydropyridines; Dose-Response Relationship, Drug; Drug Resistance; Humans; In Vitro Techniques; Membrane Glycoproteins; Verapamil; Vincristine | 1990 |
The solvents cremophor EL and Tween 80 modulate daunorubicin resistance in the multidrug resistant Ehrlich ascites tumor.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carcinoma, Ehrlich Tumor; Cyclosporins; Daunorubicin; Dihydropyridines; Drug Resistance; Drug Synergism; Drug Therapy, Combination; Glycerol; Humans; Intracellular Membranes; Membrane Glycoproteins; Polysorbates; Tritium; Tumor Cells, Cultured; Verapamil | 1990 |
Heparin binds with high affinity to voltage-dependent L-type Ca2+ channels. Evidence for an agonistic action.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Calcium Channels; Carps; Cell Membrane; Cerebral Cortex; Dihydropyridines; Diltiazem; Electric Conductivity; Guinea Pigs; Heparin; Isradipine; Molecular Sequence Data; Muscles; Myocardium; Nicotinic Antagonists; Oxadiazoles; Polyelectrolytes; Polymers; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil | 1990 |
[3H]-nitrendipine binding in normal and cardiomyopathic hamster hearts: modulation by temperature, verapamil and diltiazem.
Topics: Allosteric Regulation; Animals; Binding Sites; Calcium Channels; Cardiomyopathies; Cricetinae; Dihydropyridines; Diltiazem; In Vitro Techniques; Kinetics; Male; Myocardium; Nitrendipine; Temperature; Verapamil | 1990 |
High and low affinity states of the dihydropyridine and phenylalkylamine receptors on the cardiac calcium channel and their interconversion by divalent cations.
Topics: Animals; Calcium; Cations, Divalent; Chickens; Dihydropyridines; Heart; Ion Channels; Isradipine; Magnesium; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil | 1985 |
Calcium channels: basic properties as revealed by radioligand binding studies.
Topics: Affinity Labels; Animals; Azides; Binding Sites; Binding, Competitive; Brain; Calcium; Calcium Channel Blockers; Dihydropyridines; Guinea Pigs; Iodobenzenes; Ion Channels; Molecular Weight; Muscles; Neurilemma; Photochemistry; Pyridines; Sarcolemma; Verapamil | 1985 |
The effect of dihydropyridine calcium agonists and antagonists on neuronal voltage sensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Animals; Brain Chemistry; Calcium; Calcium Channel Blockers; Cell Line; Dihydropyridines; Electric Stimulation; Glioma; In Vitro Techniques; Ion Channels; Neuroblastoma; Neurons; Nifedipine; Potassium; Pyridines; Rats; Synaptosomes; Verapamil | 1986 |
Purified calcium channels have three allosterically coupled drug receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Amines; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil | 1986 |
Dihydropyridine calcium antagonists and agonists in the isolated perfused Dahl rat kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Glomerular Filtration Rate; Hypertension, Renal; In Vitro Techniques; Ion Channels; Kidney; Male; Nitrendipine; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Renal Circulation; Sodium Chloride; Verapamil | 1987 |
The 165-kDa peptide of the purified skeletal muscle dihydropyridine receptor contains the known regulatory sites of the calcium channel.
Topics: Affinity Labels; Animals; Azides; Calcium; Calcium Channels; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Molecular Weight; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Verapamil | 1987 |
Pertussis toxin pretreatment abolishes dihydropyridine inhibition of calcium flux in the 235-1 pituitary cell line.
Topics: Animals; Calcium; Dihydropyridines; Ion Channels; Marine Toxins; Nicardipine; Oxocins; Pertussis Toxin; Pituitary Neoplasms; Prolactin; Tumor Cells, Cultured; Verapamil; Virulence Factors, Bordetella | 1988 |
Purification and reconstitution of calcium channel drug-receptor sites.
Topics: Affinity Labels; Animals; Azides; Calcium; Calcium Channels; Dihydropyridines; Guinea Pigs; Ion Channels; Muscles; Receptors, Drug; Receptors, Nicotinic; Verapamil | 1988 |
Multiple calcium channels in synaptosomes: voltage dependence of 1,4-dihydropyridine binding and effects on function.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Male; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Synaptosomes; Verapamil | 1988 |
Ca2+ antagonists and inhibitory effects of dopamine on isolated rabbit ear artery.
Topics: Animals; Arteries; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Dopamine; Electric Stimulation; Ethanol; Female; Flunarizine; In Vitro Techniques; Muscle, Smooth, Vascular; Perfusion; Rabbits; Time Factors; Vasoconstriction; Verapamil | 1988 |
A dihydropyridine calcium channel blocker with phosphodiesterase inhibitory activity: effects on cultured vascular smooth muscle and cultured heart cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Calcium Channel Blockers; Cells, Cultured; Chick Embryo; Depression, Chemical; Dihydropyridines; Dose-Response Relationship, Drug; Muscle, Smooth, Vascular; Myocardial Contraction; Myocardium; Nifedipine; Phosphodiesterase Inhibitors; Rats; Verapamil | 1988 |
Voltage-dependent calcium channels in skeletal muscle transverse tubules. Measurements of calcium efflux in membrane vesicles.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Benzothiazoles; Calcium Channel Blockers; Calcium Channels; Calcium Radioisotopes; Carbocyanines; Cell Membrane; Dihydropyridines; Edetic Acid; Fluorescent Dyes; Isradipine; Lanthanum; Membrane Potentials; Muscles; Nitrendipine; Oxadiazoles; Potassium; Rabbits; Verapamil | 1989 |
Effect of age and of hypertrophy on cardiac Ca2+ antagonist binding sites.
Topics: Aging; Animals; Blood Pressure; Body Weight; Calcium Channels; Cardiomegaly; Cell Membrane; Dihydropyridines; Indicators and Reagents; Isradipine; Male; Myocardium; Oxadiazoles; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Receptors, Nicotinic; Time Factors; Verapamil | 1989 |
Dihydropyridines modulate K+-evoked amino acid and adenosine release from cerebellar neuronal cultures.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine; Amino Acids; Animals; Calcium Channel Blockers; Cells, Cultured; Cerebellum; Dihydropyridines; Potassium; Rats; Verapamil | 1989 |
Molecular properties of voltage-activated calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Affinity Labels; Animals; Azides; Calcium Channels; Cloning, Molecular; Dihydropyridines; DNA; Glycoproteins; Muscles; Phosphorylation; Protein Conformation; Protein Kinases; Receptors, Nicotinic; Verapamil | 1989 |
Evidence of altered dihydropyridine receptor binding capacity following cardiac transplantation.
Topics: Animals; Binding, Competitive; Calcium Channels; Dihydropyridines; Dogs; Graft Rejection; Heart Transplantation; Nifedipine; Nitrendipine; Receptors, Nicotinic; Sarcolemma; Verapamil | 1989 |
Is Ca2+ antagonists binding protein from cytosolic fraction the precursor of alpha 1-subunit of Ca2+ channel?
Topics: Affinity Labels; Animals; Antibodies; Azides; Binding, Competitive; Calcium Channel Blockers; Calcium Channels; Cytoplasm; Dihydropyridines; In Vitro Techniques; Isradipine; Muscles; Oxadiazoles; Protein Precursors; Rabbits; Radioligand Assay; Receptors, Nicotinic; Ultraviolet Rays; Verapamil | 1989 |
Progesterone interacts with P-glycoprotein in multidrug-resistant cells and in the endometrium of gravid uterus.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Line; Dihydropyridines; Drug Resistance; Endometrium; Estradiol; Female; Intracellular Membranes; Kinetics; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Microsomes; Pregnancy; Pregnancy, Animal; Progesterone; Protein Binding; Steroids; Verapamil; Vinblastine | 1989 |
[Classification of Ca antagonist by its chemical structure and characteristics of each derivative].
Topics: Calcium Channel Blockers; Chemical Phenomena; Chemistry; Dihydropyridines; Diltiazem; Drug Interactions; Humans; Membrane Potentials; Structure-Activity Relationship; Verapamil | 1989 |
3H-azidopine photoaffinity labeling of high molecular weight proteins in chloroquine resistant falciparum malaria.
Topics: Affinity Labels; Animals; Azides; Binding, Competitive; Chloroquine; Chlorpromazine; Dihydropyridines; Drug Resistance; Glycoproteins; Molecular Weight; Nicardipine; Photochemistry; Plasmodium falciparum; Proteins; Quinacrine; Reserpine; Trifluoperazine; Verapamil | 1989 |
Potent and specific inhibition of IL-8-, IL-1 alpha- and IL-1 beta-induced in vitro human lymphocyte migration by calcium channel antagonists.
Topics: Calcium Channel Blockers; Chemotactic Factors; Chemotaxis, Leukocyte; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Interleukin-1; Interleukin-8; Interleukins; Kinetics; Lymphocytes; Nifedipine; Recombinant Proteins; Verapamil | 1989 |
Photoaffinity-labelling of the calcium-channel-associated 1,4-dihydropyridine and phenylalkylamine receptor in guinea-pig hippocampus. A 195 kDa polypeptide carries both drug receptors and has similarities to the alpha 1 subunit of the purified skeletal-m
Topics: Affinity Labels; Animals; Azides; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Dihydropyridines; Guinea Pigs; Hippocampus; In Vitro Techniques; Kinetics; Muscles; Peptides; Radioimmunoassay; Receptors, Nicotinic; Tritium; Verapamil | 1988 |
Targets for calcium channel blockers in mammalian skeletal muscle and their respective functions in excitation-contraction coupling.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Evoked Potentials; Isradipine; Mice; Muscle Contraction; Oxadiazoles; Piperidines; Thiazines; Verapamil | 1988 |
Role of G-proteins in mediating dihydropyridine receptor coupling with voltage sensitive calcium channels.
Topics: Animals; Calcium Channels; Cell Line; Dihydropyridines; GTP-Binding Proteins; Marine Toxins; Nicardipine; Oxocins; Rats; Receptors, Nicotinic; Verapamil; Virulence Factors, Bordetella | 1988 |
A novel high affinity class of Ca2+ channel blockers.
Topics: Animals; Bepridil; Binding Sites; Calcium Channel Blockers; Cell Line; Dihydropyridines; Fluspirilene; Isradipine; Kinetics; Muscles; Oxadiazoles; Piperidines; Pyrrolidines; Rabbits; Rats; Structure-Activity Relationship; Thiazines; Verapamil | 1988 |
(-)-[3H] desmethoxyverapamil labels multiple calcium channel modulator receptors in brain and skeletal muscle membranes: differentiation by temperature and dihydropyridines.
Topics: Animals; Brain Chemistry; Calcium; Calcium Channels; Cell Membrane; Dihydropyridines; Female; Isradipine; Kinetics; Male; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Stereoisomerism; Temperature; Tritium; Verapamil | 1986 |
Interaction between Ca2+ antagonists and digitalis.
Topics: Calcium Channel Blockers; Digitalis; Dihydropyridines; Diltiazem; Drug Interactions; Humans; Plants, Medicinal; Plants, Toxic; Verapamil | 1988 |
The calcium channel antagonist omega-conotoxin inhibits secretion from peptidergic nerve terminals.
Topics: Animals; Arginine Vasopressin; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Mollusk Venoms; Nerve Endings; Nicardipine; omega-Conotoxin GVIA; Pituitary Gland, Posterior; Potassium; Rats; Reference Values; Verapamil | 1988 |
[Calcium inhibitors and treatment of arterial hypertension].
Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Hypertension; Verapamil | 1988 |
A novel 1,4-dihydropyridine-binding site on mitochondrial membranes from guinea-pig heart, liver and kidney.
Topics: Animals; Binding Sites; Centrifugation, Density Gradient; Dihydropyridines; Diltiazem; Guinea Pigs; Intracellular Membranes; Kidney; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Nitrendipine; Osmolar Concentration; Subcellular Fractions; Verapamil | 1988 |
The antithrombogenic in vivo effects of calcium channel blockers in experimental thrombosis in mice.
Topics: Animals; Calcium Channel Blockers; Collagen; Dihydropyridines; Diltiazem; Disease Models, Animal; Dose-Response Relationship, Drug; Epinephrine; Male; Mice; Mice, Inbred Strains; Nifedipine; Thrombosis; Time Factors; Verapamil | 1987 |
Effects of calcium antagonists on phencyclidine behaviors.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Male; Mice; Motor Activity; Motor Skills; Nifedipine; Phencyclidine; Prazosin; Pyridines; Verapamil | 1986 |
The interaction of phenylalkylamine calcium channel blockers with the 1,4-dihydropyridine binding site.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Dihydropyridines; Heart; Kinetics; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Drug; Structure-Activity Relationship; Verapamil | 1986 |
Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.
Topics: Animals; Binding Sites; Cattle; Dihydropyridines; Electrophysiology; Heart Conduction System; Ion Channels; Membrane Potentials; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Purkinje Fibers; Pyridines; Verapamil | 1984 |
(-)-3H-desmethoxyverapamil labelling of putative calcium channels in brain: autoradiographic distribution and allosteric coupling to 1,4-dihydropyridine and diltiazem binding sites.
Topics: Animals; Autoradiography; Benzazepines; Binding Sites; Brain; Dihydropyridines; Diltiazem; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Kinetics; Membranes; Pyridines; Stereoisomerism; Verapamil | 1984 |
Norepinephrine-induced contractions of the rat aorta in the absence of extracellular calcium--II. Effects of calcium antagonists.
Topics: Animals; Aorta; Calcium; Calcium Channel Blockers; Culture Media; Dihydropyridines; In Vitro Techniques; Indenes; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicotinic Acids; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Verapamil | 1983 |
Differential effects of nitroglycerin, trimetazidine, verapamil and SK&F 24260 on venous return as revealed by the open-loop method in the dog.
Topics: Animals; Blood Volume; Cardiac Output; Carotid Sinus; Denervation; Dihydropyridines; Dogs; Hemodynamics; Hydrocarbons, Fluorinated; Methods; Nicotinic Acids; Nitroglycerin; Piperazines; Regional Blood Flow; Trimetazidine; Vascular Resistance; Venae Cavae; Verapamil | 1980 |
Structure-activity relationship of verapamil analogs and reversal of multidrug resistance.
Topics: Animals; Antineoplastic Agents; Aorta; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Calcium; Dihydropyridines; Doxorubicin; Drug Design; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Synergism; Humans; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger; Structure-Activity Relationship; Tumor Cells, Cultured; Tumor Stem Cell Assay; Verapamil | 1995 |
N-alkylated 1,4-dihydropyridines: new agents to overcome multidrug resistance.
Topics: Alkylation; Animals; Chemical Phenomena; Chemistry, Physical; Dihydropyridines; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Verapamil; Vincristine | 1995 |
Differential effects of verapamil and quinine on the reversal of doxorubicin resistance in a human leukemia cell line.
Topics: Affinity Labels; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dihydropyridines; Doxorubicin; Drug Resistance; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Kinetics; Leukemia, Erythroblastic, Acute; Microscopy, Confocal; Microscopy, Fluorescence; Phenotype; Quinine; Subcellular Fractions; Tumor Cells, Cultured; Verapamil | 1995 |
Novel dithiane analogues of tiapamil with high activity to overcome multidrug resistance in vitro.
Topics: Animals; Aorta; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dihydropyridines; Doxorubicin; Drug Resistance, Multiple; In Vitro Techniques; Propylamines; Rats; Stereoisomerism; Tiapamil Hydrochloride; Tumor Cells, Cultured; Verapamil; Vincristine | 1995 |
Chemosensitisation of spontaneous multidrug resistance by a 1,4-dihydropyridine analogue and verapamil in human glioma cell lines overexpressing MRP or MDR1.
Topics: Alkaloids; Antigens, Neoplasm; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Dihydropyridines; DNA Topoisomerases, Type I; DNA Topoisomerases, Type II; DNA-Binding Proteins; Doxorubicin; Drug Resistance, Multiple; Drug Synergism; Gene Expression; Glioma; Humans; Isoenzymes; Microscopy, Fluorescence; Sulfur Compounds; Tumor Cells, Cultured; Verapamil | 1995 |
Resolution and pharmacological analysis of the voltage-dependent calcium channels of Drosophila larval muscles.
Topics: Amiloride; Animals; Calcium Channels; Dihydropyridines; Diltiazem; Drosophila melanogaster; Electrophysiology; Larva; Verapamil | 1995 |
Comparison of a calcium antagonist, CD-349, with nifedipine, diltiazem, and verapamil in rabbit spontaneously beating sinoatrial node cells.
Topics: Action Potentials; Animals; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Diltiazem; Electrophysiology; Female; In Vitro Techniques; Male; Microelectrodes; Nifedipine; Rabbits; Sinoatrial Node; Verapamil | 1993 |
Differential modulation of P-glycoprotein transport by protein kinase inhibition.
Topics: Affinity Labels; Alkaloids; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Carrier Proteins; Cyclosporine; Dactinomycin; Dihydropyridines; Drug Resistance; Humans; Isoenzymes; Membrane Glycoproteins; Naphthalenes; Polycyclic Compounds; Protein Kinase C; Rhodamine 123; Rhodamines; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Verapamil; Vinblastine; Vincristine | 1993 |
Membrane stretch evoked by cell swelling increases contractile activity in vascular smooth muscle through dihydropyridine-sensitive pathways.
Topics: Animals; Calcium; Calcium Channel Blockers; Cell Membrane; Cell Size; Dihydropyridines; Diltiazem; Felodipine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Osmosis; Portal Vein; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Verapamil | 1994 |
Interaction of the P-glycoprotein multidrug transporter with peptides and ionophores.
Topics: Adenosine Triphosphatases; Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Cell Membrane; CHO Cells; Cricetinae; Dihydropyridines; Enzyme Activation; Ionophores; Peptides; Photochemistry; Protein Binding; Verapamil | 1995 |
Effects of lipids on ATPase activity of purified Chinese hamster P-glycoprotein.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Brain Chemistry; Cattle; Cell Membrane; Colchicine; Cricetinae; Cricetulus; Daunorubicin; Dihydropyridines; Escherichia coli; Lipids; Liver; Proteolipids; Sheep; Verapamil; Vinblastine | 1995 |
[Pharmacological control of heart rate].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Animals; Benzazepines; Blood Pressure; Calcium Channel Blockers; Cardiovascular Agents; Coronary Circulation; Dihydropyridines; Electrocardiography; Female; Heart Rate; Humans; In Vitro Techniques; Male; Middle Aged; Nifedipine; Population Surveillance; Rabbits; Sinoatrial Node; Tachycardia; Verapamil | 1994 |
P-glycoprotein overexpression in mouse cells does not correlate with resistance to N-benzyladriamycin-14-valerate (AD 198).
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cells, Cultured; Dihydropyridines; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Immunoblotting; Mice; Tumor Cells, Cultured; Verapamil | 1994 |
Effects of nonionic detergents on P-glycoprotein drug binding and reversal of multidrug resistance.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Carrier Proteins; Cells, Cultured; Cholic Acids; Detergents; Dihydropyridines; Drug Resistance; Humans; Membrane Glycoproteins; Octoxynol; Verapamil | 1993 |
Effect of alpha-interferon on P-glycoprotein expression and function and on verapamil modulation of doxorubicin resistance.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Carrier Proteins; Cell Line; Cricetinae; Dihydropyridines; Doxorubicin; Drug Resistance; Drug Synergism; Interferon-alpha; Membrane Glycoproteins; RNA, Messenger; Verapamil | 1994 |
Bile canalicular cationic dye secretion as a model for P-glycoprotein mediated transport.
Topics: Acridine Orange; Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Bile Canaliculi; Blotting, Western; Carrier Proteins; Cell Membrane; Cyclosporine; Dihydropyridines; In Vitro Techniques; Liver; Male; Membrane Glycoproteins; Models, Biological; Perfusion; Precipitin Tests; Rats; Rats, Inbred Strains; Verapamil | 1994 |
In vitro antioxidant activity of calcium antagonists against LDL oxidation compared with alpha-tocopherol.
Topics: Adult; Amlodipine; Antioxidants; Calcium Channel Blockers; Copper; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Humans; Isradipine; Lipoproteins, LDL; Oxidation-Reduction; Reference Values; Thiobarbituric Acid Reactive Substances; Verapamil; Vitamin E | 1994 |
A role for ions in barrier recovery after acute perturbation.
Topics: Animals; Calcium; Calcium Channels; Calmodulin; Cell Membrane Permeability; Diazoxide; Dihydropyridines; Homeostasis; Ions; Mice; Mice, Hairless; Minoxidil; Ouabain; Permeability; Potassium; Potassium Channels; Skin; Skin Physiological Phenomena; Sodium-Potassium-Exchanging ATPase; Verapamil; Water-Electrolyte Balance | 1994 |
[Anticonvulsant activity of sodium valproate and various calcium antagonists during their combined use in mice].
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Epilepsy; Male; Mice; Nifedipine; Valproic Acid; Verapamil | 1993 |
Non-glucocorticoid steroid analogues (21-aminosteroids) sensitize multidrug resistant cells to vinblastine.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Survival; Dihydropyridines; Drug Interactions; Drug Resistance; Humans; KB Cells; Membrane Glycoproteins; Pregnatrienes; Structure-Activity Relationship; Verapamil; Vinblastine | 1993 |
Influence of sequential exposure to R-verapamil or B8509-035 on rhodamine 123 accumulation in human lymphoblastoid cell lines.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Differentiation; Dihydropyridines; Dose-Response Relationship, Drug; Drug Interactions; Drug Resistance; Flow Cytometry; Humans; Membrane Glycoproteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Rhodamines; Tumor Cells, Cultured; Verapamil | 1993 |
Differential effects of non-peptidic tachykinin receptor antagonists on Ca2+ channels.
Topics: Animals; Calcium Channels; Dihydropyridines; In Vitro Techniques; Isradipine; Muscles; Rats; Receptors, Tachykinin; Verapamil | 1994 |
Calcium channel antagonists. What do the second-generation agents have to offer?
Topics: Arteriosclerosis; Calcium Channel Blockers; Cardiovascular Diseases; Cerebrovascular Disorders; Dihydropyridines; Diltiazem; Heart Failure; Humans; Verapamil | 1994 |
Differential effectiveness of a range of novel drug-resistance modulators, relative to verapamil, in influencing vinblastine or teniposide cytotoxicity in human lymphoblastoid CCRF-CEM sublines expressing classic or atypical multidrug resistance.
Topics: Cyclosporine; Dihydropyridines; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Flunarizine; Humans; Leukemia, T-Cell; Piperidines; Quinidine; Teniposide; Triazines; Tumor Cells, Cultured; Verapamil; Vinblastine | 1994 |
Effect of benidipine hydrochloride (KW-3049), on cerebral ischemia induced by bilateral occlusion of the common carotid arteries in rats.
Topics: Adenosine Triphosphate; Animals; Behavior, Animal; Brain; Brain Chemistry; Brain Ischemia; Calcium Channel Blockers; Carotid Artery, Common; Dihydropyridines; Lactates; Lactic Acid; Male; Nicardipine; Nifedipine; Phosphocreatine; Potassium; Rats; Rats, Wistar; Sodium; Verapamil | 1993 |
Brain calcium channel related dihydropyridine and phenylalkylamine binding sites in Alzheimer's, Parkinson's and Huntington's diseases.
Topics: Aged; Alzheimer Disease; Autopsy; Binding Sites; Brain; Calcium; Calcium Channels; Dihydropyridines; Female; Humans; Huntington Disease; Isradipine; Male; Middle Aged; Organ Specificity; Parkinson Disease; Reference Values; Verapamil | 1993 |
Calciseptine binding to a 1,4-dihydropyridine recognition site of the L-type calcium channel of rat synaptosomal membranes.
Topics: Animals; Brain; Calcium Channel Blockers; Calcium Channels; Cell Fractionation; Dihydropyridines; Diltiazem; Elapid Venoms; Intracellular Membranes; Kinetics; Ligands; Male; Nitrendipine; omega-Conotoxins; Peptides; Rats; Rats, Wistar; Synaptosomes; Verapamil | 1993 |
A light stabilizer (Tinuvin 770) that elutes from polypropylene plastic tubes is a potent L-type Ca(2+)-channel blocker.
Topics: Alkaloids; Animals; Benzylisoquinolines; Binding, Competitive; Calcium Channel Blockers; Cell Line; Decanoic Acids; Dihydropyridines; Diltiazem; Guinea Pigs; Heart; In Vitro Techniques; Piperidines; Polypropylenes; Rabbits; Swine; Verapamil | 1993 |
Studies on the glomerular microcirculatory actions of manidipine and its modulation of the systemic and renal effects of endothelin.
Topics: Animals; Arginine; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Endothelins; Glomerular Filtration Rate; Hemodynamics; Kidney Glomerulus; Male; Microcirculation; Nitric Oxide; Nitrobenzenes; omega-N-Methylarginine; Piperazines; Rats; Rats, Wistar; Vasodilation; Verapamil | 1993 |
Dihydropyridine Ca2+ channel antagonists inhibit the salvage pathway for DNA synthesis in human vascular smooth muscle cells.
Topics: Calcium Channel Blockers; Cell Division; Cells, Cultured; Dihydropyridines; Diltiazem; DNA; Epidermal Growth Factor; Felodipine; Gene Expression Regulation; Genes, fos; Humans; Immunoblotting; Mammary Arteries; Muscle, Smooth, Vascular; Nisoldipine; Thymidine; Verapamil | 1993 |
Reversal of multidrug resistance in Friend leukemia cells by dexniguldipine-HCl.
Topics: Animals; Cell Division; Daunorubicin; Dihydropyridines; Dose-Response Relationship, Drug; Drug Resistance; Friend murine leukemia virus; Leukemia, Erythroblastic, Acute; Mice; Tumor Cells, Cultured; Verapamil | 1993 |
The use of calcium channel blockers in general practice.
Topics: Calcium Channel Blockers; Cardiovascular Diseases; Dihydropyridines; Diltiazem; Family Practice; Female; Humans; Male; Verapamil | 1993 |
Analgesic effects of intracerebroventricular administration of calcium channel blockers in mice.
Topics: Analgesics; Animals; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Injections, Intraventricular; Mice; Naloxone; Pain Measurement; Pain Threshold; Piperazines; Verapamil | 1993 |
Characterization of calcium channel blocker induced smooth muscle relaxation using a model of isolated corpus cavernosum.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Electric Stimulation; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Norepinephrine; Penis; Rabbits; Verapamil | 1993 |
Decreased potency of MDR-modulators under serum conditions determined by a functional assay.
Topics: Acute Disease; Antimetabolites, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; CD8-Positive T-Lymphocytes; Cyclosporine; Dihydropyridines; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Flow Cytometry; Humans; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid; Rhodamine 123; Rhodamines; Verapamil | 1995 |
Dihydropyridines, phenylalkylamines and benzothiazepines block N-, P/Q- and R-type calcium currents.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Ganglia, Spinal; Heart; Homovanillic Acid; In Vitro Techniques; Ion Channel Gating; Mice; Motor Neurons; Myocardium; Neurons, Afferent; Nimodipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; Patch-Clamp Techniques; Peptides; Rats; Rats, Sprague-Dawley; Spider Venoms; Verapamil | 1995 |
Ca2+ channel blockers modulate metabolism of collagens within the extracellular matrix.
Topics: Amlodipine; Becaplermin; Calcium Channel Blockers; Cells, Cultured; Collagen; Collagenases; Dihydropyridines; Diltiazem; Enzyme Activation; Extracellular Matrix; Felodipine; Fibroblasts; Humans; Kinetics; Lung; Metalloendopeptidases; Muscle, Smooth, Vascular; Nitrobenzenes; Piperazines; Platelet-Derived Growth Factor; Procollagen; Proline; Proto-Oncogene Proteins c-sis; Transcription, Genetic; Verapamil | 1996 |
Myocardial and vascular effects of efonidipine in vitro as compared with nifedipine, verapamil and diltiazem.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Nitrophenols; Organophosphorus Compounds; Potassium Chloride; Rats; Rats, Wistar; Verapamil | 1996 |
Pharmacological analysis of voltage-dependent potassium currents in cultured skeletal myocytes of the frog Rana temporaria.
Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Electric Conductivity; Embryo, Nonmammalian; Membrane Potentials; Muscle, Skeletal; Nifedipine; Patch-Clamp Techniques; Potassium Channels; Quinidine; Rana temporaria; Time Factors; Verapamil | 1995 |
BIBW22 BS, potent multidrug resistance-reversing agent, binds directly to P-glycoprotein and accumulates in drug-resistant cells.
Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Cell Line; Cell Survival; CHO Cells; Colchicine; Cricetinae; Dihydropyridines; Doxorubicin; Drug Resistance, Multiple; Humans; Kinetics; Lymphoma; Morpholines; Peptide Mapping; Protein Binding; Triamterene; Tumor Cells, Cultured; Verapamil; Vinblastine | 1996 |
Effects of the selective bisindolylmaleimide protein kinase C inhibitor GF 109203X on P-glycoprotein-mediated multidrug resistance.
Topics: 3T3 Cells; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Dihydropyridines; Drug Resistance, Multiple; Enzyme Inhibitors; Gene Expression; Humans; Indoles; Maleimides; Mice; Phosphorylation; Protein Kinase C; Verapamil | 1996 |
Pharmacological activity of the new calcium antagonist, lacidipine, on isolated preparations.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Coronary Circulation; Dihydropyridines; Female; Heart; Heart Rate; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Myocardial Contraction; Nifedipine; Rabbits; Ventricular Pressure; Verapamil | 1996 |
Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation.
Topics: Adenosine Diphosphate; Animals; Antioxidants; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Diltiazem; Felodipine; Fumarates; Heart; Iron; Lipid Peroxidation; Male; Myocardium; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Verapamil | 1996 |
Differential effects of a K+ channel agonist and Ca2+ antagonists on myosin light chain phosphorylation in relaxation of endothelin-1-contracted tracheal smooth muscle.
Topics: Animals; Benzopyrans; Dihydropyridines; Endothelin-1; Muscle Relaxation; Muscle, Smooth; Myosin Light Chains; Nitrendipine; Sheep; Trachea; Verapamil | 1997 |
Relationship between the inhibition of azidopine binding to P-glycoprotein by MDR modulators and their efficiency in restoring doxorubicin intracellular accumulation.
Topics: Affinity Labels; Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cyclosporine; Cyclosporins; Dihydropyridines; Doxorubicin; Drug Resistance, Multiple; Humans; Mice; Nicardipine; Piperidines; Triazines; Tumor Cells, Cultured; Verapamil | 1996 |
Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins.
Topics: Affinity Labels; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blotting, Western; Cell Survival; Cyclosporins; Dihydropyridines; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Humans; Neoplasm Proteins; Phenotype; Polymerase Chain Reaction; Prazosin; Rhodamine 123; Rhodamines; Sarcoma; Vault Ribonucleoprotein Particles; Verapamil | 1997 |
Binding and distribution of three prototype calcium channel blockers in perfused rat liver.
Topics: Animals; Azides; Calcium Channel Blockers; Calcium Channels; Carbon Radioisotopes; Dihydropyridines; Inulin; Isradipine; Liver; Models, Biological; Perfusion; Rats; Rats, Sprague-Dawley; Time Factors; Tritium; Urea; Verapamil | 1997 |
Involvement of both calcium influx and calcium mobilization in growth hormone-induced [Ca2+]i increases in Chinese hamster ovary cells.
Topics: Animals; Calcium; Calcium Channels; CHO Cells; Cricetinae; Dihydropyridines; Growth Hormone; Intracellular Fluid; Patch-Clamp Techniques; Rabbits; Thapsigargin; Verapamil | 1997 |
Effect of calcium antagonists on plasma norepinephrine levels, heart rate, and blood pressure.
Topics: Adult; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Drug Administration Routes; Follow-Up Studies; Heart Rate; Humans; Hypertension; MEDLINE; Middle Aged; Norepinephrine; Retrospective Studies; Time Factors; Verapamil | 1997 |
[Stable angina pectoris: what is the role of calcium antagonists?].
Topics: Adrenergic beta-Antagonists; Angina Pectoris; Atenolol; Calcium Channel Blockers; Clinical Trials as Topic; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Felodipine; Humans; Metoprolol; Multicenter Studies as Topic; Nifedipine; Randomized Controlled Trials as Topic; Verapamil | 1997 |
In vivo reversibility of multidrug resistance by the MDR-modulator dexniguldipine (niguldipine derivative B859-35) and by verapamil.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Dihydropyridines; Drug Resistance, Neoplasm; Humans; Immunohistochemistry; Male; Mice; Mice, Nude; Neoplasm Transplantation; Tumor Cells, Cultured; Verapamil | 1996 |
Isradipine and lacidipine: effects in vivo and in vitro on Trypanosoma cruzi epimastigotes.
Topics: Animals; Calcium Channel Blockers; Cattle; Dihydropyridines; Diltiazem; Isradipine; Oxygen Consumption; Trypanocidal Agents; Trypanosoma cruzi; Verapamil | 1998 |
Catalepsy induced by calcium channel blockers in mice.
Topics: Amlodipine; Animals; Binding, Competitive; Calcium Channel Blockers; Catalepsy; Dihydropyridines; Diltiazem; Disease Models, Animal; Flunarizine; Male; Mice; Muscarinic Antagonists; Nitrobenzenes; Piperazines; Predictive Value of Tests; Receptors, Cholinergic; Receptors, Dopamine D1; Receptors, Dopamine D2; Scopolamine; Time Factors; Verapamil | 1998 |
Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Calcium Channel Blockers; CHO Cells; Cricetinae; Cytotoxins; Dihydropyridines; Drug Resistance, Multiple; Fibroblasts; Nicardipine; Nimodipine; Nitrendipine; Protein Binding; Verapamil; Vinblastine | 1998 |
Ca2+ channel modulation alters halothane-induced depression of ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthetics, Inhalation; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Drug Synergism; Halothane; Heart Ventricles; Isradipine; Myocardial Contraction; Myocardium; Nifedipine; Rats; Rats, Wistar; Sarcolemma; Verapamil | 1998 |
Rhodamine 123 efflux modulation in the presence of low or high serum from CD56+ hematopoietic cells or CD34+ leukemic blasts by B9309-068, a newly designed pyridine derivative.
Topics: Acridines; Antigens, CD34; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Blood Proteins; Calcium Channel Blockers; CD56 Antigen; Cyclosporins; Dihydropyridines; Dose-Response Relationship, Drug; Flow Cytometry; Fluorescent Dyes; Gene Expression; Humans; Isoquinolines; Leukemia, Myeloid, Acute; Leukocytes, Mononuclear; Morpholines; Multidrug Resistance-Associated Proteins; Pyrimidines; Rhodamine 123; Rhodamines; Tetrahydroisoquinolines; Verapamil | 1998 |
Passive transfer of Lambert-Eaton myasthenic syndrome induces dihydropyridine sensitivity of ICa in mouse motor nerve terminals.
Topics: Animals; Autoantibodies; Binding, Competitive; Calcium; Calcium Channel Blockers; Dihydropyridines; Immunization, Passive; Lambert-Eaton Myasthenic Syndrome; Male; Mice; Mice, Inbred ICR; Motor Neurons; Nifedipine; omega-Agatoxin IVA; omega-Conotoxins; Peptides; Plasma; Potassium Channel Blockers; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Spider Venoms; Synaptosomes; Tetraethylammonium; Verapamil | 1998 |
In vitro efficacy of known P-glycoprotein modulators compared to droloxifene E and Z: studies on a human T-cell leukemia cell line and their resistant variants.
Topics: Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cell Division; Cyclosporins; Dihydropyridines; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Leukemia, T-Cell; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Tamoxifen; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles; Verapamil | 1998 |
Gingival hyperplasia due to calcium antagonists.
Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Gingival Hyperplasia; Humans; Nifedipine; Verapamil | 1998 |
Effects of long-acting versus short-acting calcium channel blockers among older survivors of acute myocardial infarction.
Topics: Aged; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Female; Humans; Male; Myocardial Infarction; Nicardipine; Nifedipine; Proportional Hazards Models; Retrospective Studies; Risk; Survival Analysis; Survivors; Verapamil | 1999 |
Distinctions in the molecular determinants of charged and neutral dihydropyridine block of L-type calcium channels.
Topics: Amino Acid Sequence; Amino Acid Substitution; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Line; Cell Membrane; Dihydropyridines; Humans; Isradipine; Kinetics; Membrane Potentials; Models, Molecular; Mutagenesis, Site-Directed; Patch-Clamp Techniques; Protein Structure, Secondary; Recombinant Fusion Proteins; Recombinant Proteins; Threonine; Transfection; Tyrosine; Verapamil | 1999 |
Differential blockade of rat alpha3beta4 and alpha7 neuronal nicotinic receptors by omega-conotoxin MVIIC, omega-conotoxin GVIA and diltiazem.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Dimethylphenylpiperazinium Iodide; Electric Stimulation; Female; Kinetics; Membrane Potentials; Neurons; Nicotinic Agonists; omega-Conotoxin GVIA; omega-Conotoxins; Oocytes; Peptides; Rats; Receptors, Nicotinic; Time Factors; Verapamil; Xenopus laevis | 1999 |
In vitro effect of multidrug resistance modifiers on idarubicinol efflux in blasts of acute myeloid leukemia.
Topics: Antineoplastic Agents; Blast Crisis; Calcium Channel Blockers; Daunorubicin; Dihydropyridines; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Humans; Idarubicin; Leukemia, Myeloid, Acute; Tumor Cells, Cultured; Verapamil | 2000 |
Loss of cyclosporin and azidopine binding are associated with altered ATPase activity by a mutant P-glycoprotein with deleted phe(335).
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Calcium Channel Blockers; Cyclosporine; Dihydropyridines; Drug Interactions; Enzyme Activation; Humans; Molecular Sequence Data; Phenylalanine; Photoaffinity Labels; Tritium; Tumor Cells, Cultured; Vanadates; Verapamil | 2000 |
The effects of calcium channel blockers on nuclear factor kappa B activation in the mesangium cells.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcimycin; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Carcinogens; Cells, Cultured; Dihydropyridines; Gene Expression; Genes, Reporter; Glomerular Mesangium; Humans; Ionophores; Luciferases; NF-kappa B; Nifedipine; Nitrophenols; Organophosphorus Compounds; Tetradecanoylphorbol Acetate; Verapamil | 2000 |
Enhancement of doxorubicin activity in multidrug-resistant cells by mefloquine.
Topics: Affinity Labels; Antibiotics, Antineoplastic; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Calcium Channel Blockers; Coloring Agents; Dihydropyridines; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Mefloquine; Phenotype; Rhodamine 123; Tumor Cells, Cultured; Verapamil | 2000 |
Dimeric 4-aryl-1,4-dihydropyridines as novel HIV-1 protease inhibitors--affinities to intestinal P-glycoprotein.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Dihydropyridines; Heterocyclic Compounds, 4 or More Rings; HIV Protease Inhibitors; Humans; Intestinal Mucosa; Protein Binding; Radioligand Assay; Verapamil | 2000 |
Effects of verapamil and elgodipine on isoprenaline-induced metabolic responses in rabbits.
Topics: Adipose Tissue; Animals; Blood Glucose; Brimonidine Tartrate; Calcium Channel Blockers; Colforsin; Consciousness; Dihydropyridines; Dose-Response Relationship, Drug; Epinephrine; Glucose; In Vitro Techniques; Insulin; Islets of Langerhans; Isoproterenol; Male; Metabolism; Potassium; Quinoxalines; Rabbits; Verapamil | 2001 |
Nifedipine-activated Ca(2+) permeability in newborn rat cortical collecting duct cells in primary culture.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Biological Transport; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cells, Cultured; Cytosol; Dihydropyridines; Diltiazem; Egtazic Acid; Gadolinium; Hydrogen Peroxide; Isradipine; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Lanthanum; Nifedipine; Protamines; Rats; Rats, Sprague-Dawley; Thapsigargin; Verapamil | 2001 |
Modulation of glycine responses by dihydropyridines and verapamil in rat spinal neurons.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Chloride Channels; Dihydropyridines; Drug Interactions; Glycine; Neural Inhibition; Neurons; Nicardipine; Nifedipine; Nitrendipine; Rats; Receptors, GABA-A; Receptors, Glycine; Spinal Cord; Synaptic Transmission; Verapamil | 2001 |
Novel effect of Y-24180, a presumed specific platelet activation factor receptor antagonist, on Ca2+ levels and growth of human prostate cancer cells.
Topics: Adenosine Triphosphate; Azepines; Calcium; Calcium Signaling; Cell Proliferation; Dihydropyridines; Diltiazem; Enzyme Inhibitors; Fura-2; Humans; Male; Phorbol Esters; Platelet Membrane Glycoproteins; Prostatic Neoplasms; Protein Kinase C; Receptors, G-Protein-Coupled; Signal Transduction; Thapsigargin; Triazoles; Tumor Cells, Cultured; Verapamil | 2004 |
Marrubenol interacts with the phenylalkylamine binding site of the L-type calcium channel.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diterpenes; Furans; Ileum; In Vitro Techniques; Isradipine; Male; Membranes; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Radioligand Assay; Rats; Rats, Wistar; Vasodilator Agents; Verapamil | 2004 |
A comparison between calcium channel blocking drugs with different potencies for T- and L-type channels in preventing atrial electrical remodeling.
Topics: Administration, Oral; Animals; Atrial Fibrillation; Atrioventricular Node; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cardiac Pacing, Artificial; Dihydropyridines; Dogs; Electrophysiology; Forecasting; Heart Atria; Japan; Male; Nitrophenols; Organophosphorus Compounds; Refractory Period, Electrophysiological; Research Design; Time Factors; Verapamil | 2004 |
Opposite effects of a single IIIS5 mutation on phenylalkylamine and dihydropyridine interaction with L-type Ca2+ channels.
Topics: Animals; Brain; Calcium; Calcium Channels; Calcium Channels, L-Type; Carrier Proteins; Cell Membrane; Dihydropyridines; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Gallopamil; Homozygote; In Situ Hybridization; Isradipine; Kinetics; Mice; Mice, Transgenic; Microsomes; Models, Biological; Mutation; Oocytes; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; RNA, Complementary; Steroid Isomerases; Tyrosine; Verapamil; Xenopus laevis | 2004 |
Case studies in hypertension. Dihydropyridine/nondihydropyridine calcium channel blocker combination therapy.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Nifedipine; Verapamil | 2005 |
Evaluation of anticancer effects of newly synthesized dihydropyridine derivatives in comparison to verapamil and doxorubicin on T47D parental and resistant cell lines in vitro.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Dihydropyridines; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Inhibitory Concentration 50; Time Factors; Verapamil | 2008 |
Inclusion of patients who overdose with dihydropyridine calcium channel blockers would potentially increase clinical utility of hyperglycemia.
Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Overdose; Heart Rate; Humans; Hyperglycemia; Patient Selection; Verapamil | 2008 |
Molecular pharmacology of human Cav3.2 T-type Ca2+ channels: block by antihypertensives, antiarrhythmics, and their analogs.
Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Calcium; Calcium Channel Blockers; Calcium Channels, T-Type; Cells, Cultured; Dihydropyridines; Humans; Mibefradil; Nitrophenols; Organophosphorus Compounds; Verapamil | 2009 |
Heterogeneity of L- and T-channels in the vasculature: rationale for the efficacy of combined L- and T-blockade.
Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Humans; Hypertension; In Vitro Techniques; Male; Mesenteric Arteries; Mibefradil; Microvessels; Nifedipine; Nitrophenols; Organophosphorus Compounds; Potassium Chloride; Rats; Rats, Sprague-Dawley; Subcutaneous Fat; Vasoconstriction; Verapamil | 2009 |
[Perspectives of inhibition of multidrug resistance during cancer chemotherapy, in vitro and in vivo experiments].
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cytomegalovirus; Dihydropyridines; Disease Progression; Diterpenes; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; HSP90 Heat-Shock Proteins; Humans; Mice; Mice, Inbred DBA; Phenothiazines; Phenotype; Propylamines; Tylosin; Verapamil | 2009 |
Is combined L- and T-channel blockade better than L-channel blockade in therapy?
Topics: Animals; Aorta; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Dihydropyridines; Drug Synergism; Humans; Hypertension; Mesenteric Arteries; Mibefradil; Microvessels; Nifedipine; Nitrophenols; Rats; Vasoconstriction; Verapamil | 2009 |
Structural model for phenylalkylamine binding to L-type calcium channels.
Topics: Amino Acid Sequence; Binding Sites; Calcium Channel Blockers; Calcium Channels, L-Type; Computer Simulation; Dihydropyridines; Gallopamil; Models, Molecular; Molecular Sequence Data; Molecular Structure; Monte Carlo Method; Protein Structure, Tertiary; Sequence Alignment; Structure-Activity Relationship; Verapamil | 2009 |
Efonidipine, a Ca(2+)-channel blocker, enhances the production of dehydroepiandrosterone sulfate in NCI-H295R human adrenocortical carcinoma cells.
Topics: Adrenocortical Carcinoma; Angiotensin II; Bucladesine; Calcium Channel Blockers; Cell Line, Tumor; Dehydroepiandrosterone Sulfate; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Humans; Hydrocortisone; Nitrophenols; Organophosphorus Compounds; Phosphoproteins; RNA, Messenger; Verapamil | 2011 |
Calcium channel antagonist exposures reported to the Poisons Information Center Erfurt.
Topics: Adolescent; Adult; Age Distribution; Aged; Calcium Channel Blockers; Child; Dihydropyridines; Diltiazem; Drug Overdose; Drug Synergism; Germany; Humans; Infant; Middle Aged; Poison Control Centers; Retrospective Studies; Verapamil; Young Adult | 2011 |
T-type calcium channel blockade improves survival and cardiovascular function in thalassemic mice.
Topics: Animals; Azoles; Base Sequence; beta-Thalassemia; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, T-Type; Cardiovascular System; Deferoxamine; Dihydropyridines; Disease Models, Animal; DNA Primers; Heart Rate; Humans; Iron; Iron Chelating Agents; Iron, Dietary; Isoindoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Nifedipine; Nitrophenols; Organ Size; Organophosphorus Compounds; Organoselenium Compounds; RNA, Messenger; Ventricular Function, Left; Verapamil | 2012 |
Ferric iron uptake into cardiomyocytes of β-thalassemic mice is not through calcium channels.
Topics: Animals; Azoles; beta-Thalassemia; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Calcium Channels, T-Type; Cation Transport Proteins; Cell Survival; Cells, Cultured; Deferoxamine; Dihydropyridines; Disease Models, Animal; Ferric Compounds; Heart Ventricles; Iron Overload; Isoindoles; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocytes, Cardiac; Nitrophenols; Organophosphorus Compounds; Organoselenium Compounds; Quaternary Ammonium Compounds; Receptors, Transferrin; Verapamil | 2013 |
Adverse event potentially due to an interaction between ibrutinib and verapamil: a case report.
Topics: Adenine; Aged; Antihypertensive Agents; Antineoplastic Agents; Cytochrome P-450 CYP3A Inhibitors; Diarrhea; Dihydropyridines; Drug Interactions; Humans; Lymphoma, Mantle-Cell; Male; Piperidines; Pyrazoles; Pyrimidines; Verapamil | 2016 |
Structural basis for inhibition of a voltage-gated Ca
Topics: Allosteric Regulation; Amines; Amlodipine; Animals; Bacterial Proteins; Binding Sites; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Line; Crystallography, X-Ray; Dihydropyridines; Lipids; Models, Molecular; Moths; Mutation; Niacin; Protein Subunits; Verapamil | 2016 |
Moderate hypothermia and responses to calcium channel blockers - Role of the nitric oxide.
Topics: Amlodipine; Animals; Calcium Channel Blockers; Cattle; Cold Temperature; Coronary Vessels; Dihydropyridines; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hypothermia, Induced; In Vitro Techniques; Nitric Oxide; Nitric Oxide Synthase Type III; Vasodilation; Vasodilator Agents; Verapamil | 2018 |
Selectivity of Ca
Topics: Animals; Antihypertensive Agents; Aorta; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Dose-Response Relationship, Drug; Esophageal Sphincter, Lower; Gastroesophageal Reflux; In Vitro Techniques; Male; Muscle Contraction; Nifedipine; Potassium Chloride; Rats, Wistar; Verapamil | 2018 |