verapamil has been researched along with digoxin in 337 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 147 (43.62) | 18.7374 |
| 1990's | 53 (15.73) | 18.2507 |
| 2000's | 78 (23.15) | 29.6817 |
| 2010's | 50 (14.84) | 24.3611 |
| 2020's | 9 (2.67) | 2.80 |
| Authors | Studies |
|---|---|
| Adachi, Y; Sugiyama, Y; Suzuki, H | 1 |
| Abe, T; Itoh, T; Kato, Y; Kusuhara, H; Meier, PJ; Shitara, Y; Sugiyama, D; Sugiyama, Y | 1 |
| Fischer, H; Huwyler, J; Poli, S; Schwab, D; Tabatabaei, A | 1 |
| Thakker, DR; Troutman, MD | 1 |
| Dagenais, C; Graff, CL; Pollack, GM | 1 |
| Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P | 1 |
| Collett, A; Hallifax, D; Tanianis-Hughes, J; Warhurst, G | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L | 1 |
| Avdeef, A; Tam, KY | 1 |
| Chen, X; Lin, X; Skolnik, S; Wang, J | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Beauchemin, S; Laurin, LP; Leblond, FA; Michaud, J; Naud, J; Pichette, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Ang, CW; Avery, VM; Blaskovich, MAT; Butler, MS; Cooper, MA; Debnath, A; Hahn, HJ; Jarrad, AM; Jones, AJ; Karoli, T; Pelingon, R; Sykes, ML; Tan, L; West, NP; Woods, K | 1 |
| Adams, JL; Akhtar, A; Chen, Y; Jaishankar, P; Pemberton, OA; Renslo, AR; Shaw, LN | 1 |
| Bukhari, S; Cabral, AD; de Araujo, ED; Gawel, JM; Gunning, PT; He, L; Johns, AE; Manaswiyoungkul, P; Nawar, N; Olaoye, OO; Raouf, YS; Sedighi, A; Shouksmith, AE; Sina, D | 1 |
| Esaki, T; Kawashima, H; Komura, H; Kuroda, M; Mizuguchi, K; Natsume-Kitatani, Y; Ohashi, R; Watanabe, R | 1 |
| Acevedo, O; Dasararaju, G; Devadasan, V; Halakova, D; Jayaprakash, V; Kovacikova, L; Mohd Siddique, MU; Mondal, SK; Prnova, MS; Shilkar, D; Stefek, M; Thakur, A; Yasmin, S | 1 |
| Ahuja, VT; Allen, J; Bristow, LJ; Bronson, JJ; Brown, JM; Camac, D; Dandapani, K; Dokania, M; Dzierba, CD; Easton, A; Elavazhagan, S; Gulianello, M; Hamman, BD; Hartz, RA; Hunihan, L; Kiefer, SE; Kostich, W; Kumar, CMV; Lewis, M; Lippy, JS; Macor, JE; Muckelbauer, JK; Nara, SJ; Pattipati, SN; Rajamani, R; Surti, N | 1 |
| Donaldson, RM | 1 |
| Bouzo, H | 1 |
| Stefan, G | 2 |
| Short, D | 1 |
| David, D; Di Segni, E; Kaplinsky, E; Klein, HO; Pauzner, H | 1 |
| Schümann, HJ; Springer, W; Wagner, J | 1 |
| Doenecke, VP | 1 |
| Cargnelli, G; Domeneghetti, F; Ferrari, M; Malacini, P; Roberti, G | 1 |
| Dreifus, L; Satinsky, JD | 1 |
| Eschenbacher, HL; Gutheil, H; Singer, H | 1 |
| Hirai, M; Hori, R; Kioka, N; Komano, T; Okamura, N; Tanigawara, Y; Ueda, K; Yasuhara, M | 1 |
| de Lannoy, IA; Silverman, M | 1 |
| Denisiuk, VI; Kotsuta, GI; Lipnitskiĭ, TN; Osiadlaia, ES; Pilipchuk, VP; Stepaniuk, AV | 1 |
| Grupp, G; Grupp, I; Heikkila, J; Luomanmaki, K; Pesola, MK; Ramo, MP; Schroder, T | 1 |
| Dobrotvorskaia, TE; Kazakevich, EV; Kotlov, AP; Kuznetsova, LA | 1 |
| Hedman, A | 1 |
| Junkin, P; Riley, CM | 1 |
| Andrews, TC; Antman, EM; Berlin, JA; Reimold, SC | 1 |
| Ashavaid, TF; Colvin, RA; Katz, AM; Messineo, FC | 1 |
| Bauman, JL; Ezri, M; Nazari, J; Tworek, DA | 1 |
| Carroll, TR; Morgan, RA; Mousa, SA | 1 |
| Haraguchi, M; Kusukawa, R; Matsuda, M; Matsuda, Y; Tada, T; Takahashi, T; Yamagishi, T | 1 |
| Hasin, Y; Horowitz, JD; Louis, WJ; Powell, AC | 1 |
| Angelin, B; Arvidsson, A; Beck, O; Dahlqvist, R; Hedman, A; Nilsson, B; Olsson, M; Schenck-Gustafsson, K | 1 |
| Christensen, C | 1 |
| Häusler, M; Schwingshandl, J; Stein, JI | 1 |
| Mazur, NA; Shestakova, NV | 1 |
| Lindemann, JP | 1 |
| Arbenz, U; Baumann, H; Dudenhausen, J; Huch, A; Karrer, G; Vetter, K | 1 |
| Sreeram, N; Wren, C | 1 |
| Halck, S; Johannessen, AC; Klitgaard, NA; Rendtorff, C | 1 |
| Fabian, M; Goh, KC; Niklas, CL; Raghuveer, MR; Sanford, D; Siegel, JH | 1 |
| Lucchesi, BR; Lynch, JJ | 1 |
| Camm, AJ; Parker, DJ; Wafa, SS; Ward, DE | 1 |
| Das, G; Michelson, EL; Platia, EV; Porterfield, JK | 1 |
| Lin, FC; Wu, DL; Yeh, SJ | 1 |
| Stahl, H | 1 |
| Bald, R; Gembruch, U; Hansmann, M; Manz, M; Nitsch, J; Redel, DA; Rüddel, H; Schlebusch, H | 1 |
| Abdul-Hussein, NF; Arrabi, WM; Kanj, NA; Khuri, MY; Nassar, CF | 1 |
| Ahuja, RC; Hasan, M; Jain, AK; Saran, RK; Sinha, N | 1 |
| Orynchak, MA | 3 |
| Channer, KS; James, MA; Papouchado, M; Rees, JR | 1 |
| Cepeláková, H; Hapala, J; Smíd, J; Topinka, I; Topolcan, O; Vainer, J | 1 |
| Jarenwattananon, M; Kaplanski, J; Nudel, DB; Weinhouse, E | 1 |
| Henry, M; Kay, MM; Viccellio, P | 1 |
| Baciewicz, AM; Bekemeyer, WB; Self, TH | 1 |
| Hinohara, Y; Homma, N; Kuromaru, O; Sakai, K; Yamazaki, T | 1 |
| Hurst, JW; Talley, JD; Wathen, MS | 1 |
| Channer, KS; James, M | 1 |
| Hoch, K; Johnson, BF; Johnson, J; Marwaha, R; Wilson, J | 1 |
| Johnson, BF; Johnson, J; Ritchie, P; Rodin, SM; Wilson, J | 1 |
| Campbell, WA; Nochimson, DJ; Soberman, SM; Vintzileos, AM | 1 |
| Lewis, RV; McDevitt, DG | 1 |
| Clark, RF; Garnett, AR; Gonzalez, ER; Hallagan, LF; Ornato, JP; Reese, WA; Tayal, VS | 1 |
| Barletta, G; Belli, B; Michelucci, A; Monizzi, D; Morace, G; Padeletti, L | 1 |
| Morganroth, J; Nestico, PF | 1 |
| Cameron, AD; Nimrod, CA; Walker, JJ | 1 |
| Hillis, WS; Hogg, KJ; Hornung, RS | 1 |
| Irvine, N; Lewis, RV; McDevitt, DG | 1 |
| Zatuchni, J | 2 |
| Merin, RG | 1 |
| Riley, CM | 1 |
| Beasley, CR; Challenor, V; Holgate, ST; Pomfret, SM | 1 |
| Colvin, EV; Davis, RO; Owen, J | 1 |
| Allan, LD; Crawford, DC; Curry, PV; Maxwell, DJ; Tynan, MJ | 1 |
| Chiba, S; Katsuyama, Y; Tada, A; Tsukada, M; Zenda, H | 1 |
| Channer, KS; James, MA; Papouchado, M; Pitcher, DW; Rees, JR | 1 |
| Lakhani, M; Lewis, R; McDevitt, DG; Moreland, TA | 1 |
| Gaion, RM; Gianotti, C; Maragno, I; Menozzi, L; Paleari, C; Prandoni, R; Rodighiero, V; Tropeano, PF | 1 |
| Taubert, KA | 1 |
| Kounis, NG; Mallioris, C | 1 |
| Najjar, HN; Rao, PS | 1 |
| Granat, M; Younis, JS | 1 |
| Chan, KY; Ng, MP; Tan, CL; Tay, JS; Wong, HB; Yip, WC | 1 |
| Hirsch, IA; Zauder, HL | 1 |
| Bhamra, R; Holt, DW; Miller, MR; Withers, R | 1 |
| Habbab, MA; Haft, JI | 1 |
| Beier-Scott, L; Eliastam, M; Schroeder, JS; Sternbach, GL | 1 |
| Goldenberg, LM; Gordon, M | 1 |
| Kaul, UA; Khalilullah, M; Manoharan, S | 1 |
| Eichler, HG; Gasić, S; Korn, A | 1 |
| Mariona, F; Truccone, N | 1 |
| Pedersen, KE | 2 |
| Stewart, PA; Wladimiroff, JW | 1 |
| de Grandi, P; Nguyen The, H; Stadlin, M | 1 |
| Kenny, J | 1 |
| Crowley, DC; Dick, M; Rayburn, WF; Rosenthal, A | 1 |
| Cummings, P | 1 |
| Gersh, BJ; Hammill, SC; Holmes, DR; Mair, DD; McLaran, C; Sugrue, DD | 1 |
| Genchik, G; Kaplanski, J; Weinhouse, E | 1 |
| Koren, G | 2 |
| Johannessen, AC; Poulsen, S | 1 |
| Dorigo, P; Maragno, I | 1 |
| Johannessen, A; Poulsen, S; Rendtorff, C | 1 |
| Baratto, T; Capella, G; Caprino, E; Nava, S; Negro, R; Veniani, M; Villani, R; Zolezzi, F | 1 |
| Marchlinski, FE; Miller, JM | 1 |
| André, D; Bost, M; Chouraqui, JP; Gilg, P; Jouk, PS; Racinet, P; Rossignol, AM | 1 |
| Banasiak, W; Kupczak, K; Molenda, W; Telichowski, C | 1 |
| Dorph-Petersen, A | 1 |
| Bünger, R; Gerlach, E; Kammermeier, H; Ziegler, V | 1 |
| Hunt, D; Peter, T; Sloman, G; Vohra, J | 1 |
| Grossmann, D; Mishra, BR | 1 |
| Adjan, M | 1 |
| Herin, P; Thorén, C | 1 |
| Awa, S; Linde, LM; Turner, SW | 1 |
| Schollmeyer, P | 1 |
| Mathew, B; Williams, JF | 1 |
| Opie, LH | 2 |
| Aust, PE; Belz, GG; Munkes, R | 1 |
| Hunt, D; Kertes, P | 1 |
| Camin, G; Disertori, M; Fiorentini, F; Furlanello, F; Guareneiro, M; Inama, G; Nicasi, L | 1 |
| Pflederer, W | 1 |
| Ali, C; Holt, DW; Volans, GN | 1 |
| Runge, M | 1 |
| Jahrmärker, H; Theisen, K | 1 |
| Kerr, CR | 1 |
| Sloan, RW | 1 |
| David, D; Di Segni, E; Guerrero, J; Kaplinsky, E; Klein, HO; Lang, R; Levy, A; Sareli, P; Weiss, E | 1 |
| Baessler, C; Morganroth, J; Panidis, IP | 1 |
| Fulton, KL; Hillis, LD; Winniford, MD | 1 |
| Moenning, SP | 1 |
| Benjamin, GC | 1 |
| Chuck, LH; Hollosi, G; Kidd, P; Parmley, WW; Rouleau, JL; Sievers, RE; Wikman-Coffelt, J | 1 |
| Koren, G; MacLeod, SM | 1 |
| Lafleur, C; Taubert, KA | 1 |
| Karlsson, K; Lilja, H; Lindecrantz, K; Sabel, KG | 1 |
| Goetzman, BW; Milstein, JM | 1 |
| Christiansen, BD; Klitgaard, NA; Nielsen-Kudsk, F; Pedersen, KE; Thayssen, P | 1 |
| Dijkhuizen, GH; Exalto, N; Sobotka, MA; van der Vorm, DH | 1 |
| Doering, W | 1 |
| Breckle, R; Driscoll, DJ; Hill, LM | 1 |
| Balestrazzi, M; Chiarappa, R; De Cesaris, R; Ranieri, G | 2 |
| Koren, G; MacLeod, SM; Soldin, S | 1 |
| Genchik, G; Kaplanski, J; Topaz, M; Weinhouse, E | 1 |
| Halawa, B | 2 |
| Johansson, PA; Olsson, SB | 1 |
| Golitsyn, SP; Grosu, AA; Smetnev, AS; Sokolov, SF | 1 |
| Kaplinsky, E; Klein, HO | 1 |
| Badin, A; De Petris, A; Maragno, L; Merola, P; Paleari, DC | 1 |
| Lessem, J | 1 |
| Barzilay, Z; Frand, M; Shahar, E; Shem-Tov, AA; Shohet, I | 1 |
| David, D; Di Segni, E; Gefen, J; Guerrero, J; Kaplinsky, E; Klein, HO; Lang, R; Libhaber, C; Sareli, P; Weiss, E | 1 |
| Parmley, WW; Rapcsak, M; Rouleau, JL; Sievers, R; Wikman-Coffelt, J | 1 |
| King, BD; Pitchon, R; Schneider, RR; Schweitzer, P; Stern, EH; Weiner, I | 1 |
| Christiansen, BD; Kjaer, K; Klitgaard, NA; Nielsen-Kudsk, F; Pedersen, KE | 1 |
| Schwartz, JB | 1 |
| Badin, A; De Petris, A; Maragno, I; Merola, P; Paleari, DC | 1 |
| Kounis, NG | 1 |
| Allegri, P; Cappelletti, F; Comacchio, G; De Lio, U; Maiolino, P; Morlino, T; Ometto, R; Vincenzi, M; Zanchetta, M | 1 |
| James, TN; Karp, RB; Kouchoukos, NT; Plumb, VJ; Waldo, AL; Zorn, GL | 1 |
| Di Segni, E; Guerrero, J; Kaplinsky, E; Klein, HO; Lang, R; Libhaber, C; Weiss, E | 1 |
| Harrison, DC; Kates, RE; Keefe, D; Kirsten, E; Schwartz, JB | 1 |
| Dorph-Pedersen, A; Hvidt, S; Klitgaard, NA; Pedersen, KE; Pedersen, KK | 1 |
| Barletta, GA; Bertini, G; Conti, A; Fattirolli, F; Giuntini, F; Mangialavori, G; Margheri, M; Mazzoni, D; Vannelli, P | 1 |
| Dorph-Pedersen, A; Hvidt, S; Klitgaard, NA; Nielsen-Kudsk, F; Pedersen, KE | 1 |
| Castellanos, A; Styperek, JL; Sung, RJ | 1 |
| Di Segni, E; Kaplinsky, E; Klein, HO; Lang, R | 1 |
| Karagueuzian, HS; Katzung, BG | 1 |
| Camm, J; Martin, A; Wang, R; Ward, D; Washington, H | 1 |
| Mendel, D | 1 |
| Kirikova, LT; Kostin, VI; Nesterov, IuI; Raevskaia, LG | 1 |
| Hurt, CM; Pelleg, A; Xu, J | 1 |
| Brouwer, J; Crijns, HJ; Lie, KI; Szabó, BM; van den Berg, MP | 1 |
| Decrinis, M; Kasper, K; Schulze-Bauer, C; Stark, G; Stark, U; Tritthart, HA | 2 |
| Oesterheld, JR; Shader, RI | 1 |
| Shettigar, UR | 1 |
| Gessler, P; Haas, NA; König, SA; Pufahl, C; Teufel, M | 1 |
| Kam, RM; Lee, CY; Teo, WS | 1 |
| Harper, PA; Ito, S; Koren, G; Woodland, C | 2 |
| Aiba, T; Hori, R; Okamura, N; Tanigawara, Y | 1 |
| Pace, MC; Palagiano, A | 1 |
| Saul, JP; Walsh, EP; Weindling, SN | 1 |
| Blackshear, JL; Hammill, SC; Kopecky, SL; Litin, SC; Safford, RE | 1 |
| Herbert, ME; Rutz, F; Votey, SR | 1 |
| Bauer, LA; Horn, JR; Pettit, H | 1 |
| Dillon, EC; Innes, GD; Metcalfe, C; Vertesi, L | 1 |
| Decrinis, M; Kasper, K; Lindner, W; Schwarzl, I; Stark, G; Stark, U | 1 |
| Pelleg, A; Xu, J; Zaim, S | 1 |
| Ito, S; Koren, G; Woodland, C | 2 |
| Hedman, A; Meijer, DK | 2 |
| Alvarez-Cedrón, L; Lanao, JM; López, FG | 1 |
| Bonini, W; Botto, GL; Broffoni, T | 1 |
| D'Andrea, A; Ducceschi, V; Iacono, A; Liccardo, B; Santangelo, L; Sarubbi, B | 1 |
| Alnemri, K; Myers, MG | 1 |
| Sharland, GK; Simpson, JM | 1 |
| Haft, JI; Khalighi, K | 1 |
| Artursson, P; Hidalgo, IJ; Raeissi, SD; Segura-Aguilar, J | 1 |
| Beijnen, JH; Koks, CH; Schellens, JH; Verschraagen, M | 1 |
| Boyd, RA; Randinitis, EJ; Reyner, EL; Stern, RH; Stewart, BH; Whitfield, L; Wu, X; Zegarac, EA | 1 |
| Bass, EB; Goodman, SN; Kim, N; McNamara, RL; Miller, MR; Powe, NR; Robinson, K; Segal, JB; Yu, D | 1 |
| Burk, O; Eichelbaum, M; Fromm, MF; Mettang, T; Pauli-Magnus, C; von Richter, O; Ziegler, A | 1 |
| Bäcker, A; Kramer, HJ; Meyer-Lehnert, H | 1 |
| Borst, P; Sarkadi, B; Smith, AJ; Szabo, K; Szakacs, G; van Helvoort, A; van Meer, G; Varadi, A; Welker, E | 1 |
| Almond, GL; Bania, TC; Blaufeux, B; Homel, P; Hughes, S | 1 |
| Dreisbach, AW; Kusus, M; Lertora, JJ; Simon, EE; Stapleton, DD | 1 |
| Carlson, GL; O'Neill, CA; Rowland, M; Stephens, RH; Warhurst, A; Warhurst, G | 1 |
| Lévy, S | 1 |
| Allessie, MA; Duytschaever, MF; Garratt, CJ | 1 |
| Dagenais, C; Ducharme, J; Pollack, GM | 1 |
| Borgå, O; Hultkvist-Bengtsson, U; Sababi, M | 1 |
| Bosker, HA; Crijns, HJ; Tieleman, RG; Tuinenburg, AE; Van Gelder, IC; Van Noord, T; Veeger, NJ; Volkers, C | 1 |
| Abdollah, H; Ghali, WA; Moritz, S; Sanfilippo, AJ; Simpson, CS | 1 |
| Alvarez, AI; Kim, RB; Merino, G; Prieto, JG | 1 |
| Goto, Y; Higuchi, S; Minemoto, M; Ohdo, S; Suematsu, F; Yukawa, E; Yukawa, M | 1 |
| Horinouchi, M; Komada, F; Nishiguchi, K; Ohmoto, N; Ohnishi, N; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y; Yokoyama, T | 1 |
| Freestone, B; Kamath, S; Lip, G | 2 |
| Vecht, RJ | 1 |
| Bermejo, MV; Cantón, E; Orero, A; Pemán, J; Velert, MM | 1 |
| Charman, WN; Johnson, BM; Porter, CJ | 1 |
| Kakumoto, M; Kita, T; Kobayashi, H; Nakamura, T; Okamura, N; Okumura, K; Sakaeda, T; Takara, K; Yagami, T | 1 |
| Aoki, S; Arao, T; Fuke, C; Hishida, S; Kamamoto, T; Kinoshita, H; Komeda, M; Kubota, A; Minami, T; Miyazaki, T; Motomura, H; Nishiguchi, M; Ohta, T; Ouchi, H; Taniguchi, T; Tsuda, T; Utsumi, T | 1 |
| Funakoshi, S; Kiribayashi, Y; Murakami, T; Takano, M; Yumoto, R | 1 |
| Ben-Zvi, Z; Holcberg, G; Huleihel, M; Katz, M; Lazer, S; Mazor, M; Sapir, O; Tsadkin, M | 1 |
| Batist, G; Ito, S; Koren, G; Wainer, IW; Woodland, C | 1 |
| Alberti, A; Corrada, E; Ferrari, S; Mafrici, A; Marenna, B | 1 |
| Bass, EB; Tamariz, LJ | 1 |
| Almond, G; Bania, TC; Chu, J; Perez, E | 1 |
| Blagova, OV; Bogdanova, EA; Nedostup, AV; Platonova, AA | 1 |
| Edvardsson, N; Firsovaite, V; Fredholm, O; Kronvall, T; Lindholm, CJ; Meurling, CJ; Möller, SJ; Olsson, SB; Pettersson, T; Platonov, PG; Roijer, A | 1 |
| Faulkner, MA; Lenz, NJ; Lenz, TL | 1 |
| Freestone, B; Lip, GY | 2 |
| Annaert, PP; Brouwer, KL | 1 |
| Hajdú, J; Papp, Z; Pete, B | 1 |
| Adachi, I; Kawakami, J; Kitazawa, H; Takagi, A; Yoshida, N | 1 |
| Chan, K; Jiang, ZH; Liu, L; Liu, ZQ; Wong, YF; Xu, HX; Zhou, H | 1 |
| Achiwa, K; Aungst, BJ; Kobayashi, M; Oda, M; Saikachi, Y; Saitoh, H; Tadano, K; Takahashi, Y; Yamaguchi, M; Yuhki, Y | 1 |
| Ho, TB; Leaver, SK | 1 |
| Lip, GY | 1 |
| Asahi, S; Ebihara, T; Higuchi, T; Ikemoto, K; Katoh, M; Niwa, S; Takeuchi, T; Yokoi, T; Yoshitomi, S | 1 |
| Chiou, WL; Yao, HM | 1 |
| Bosker, HA; Crijns, HJ; Hemels, ME; Ranchor, AV; Van den Berg, MP; Van Gelder, IC; Van Noord, T; Van Veldhuisen, DJ; Veeger, NJ; Wiesfeld, AC | 1 |
| Charman, SA; Katneni, K; Porter, CJ | 1 |
| Kawasaki, M; Langguth, P; Moriya, Y; Nakamura, T; Okumura, K; Omatsu, H; Sakaeda, T; Sakane, T; Shirasaka, Y; Yamashita, S | 1 |
| Asashi, S; Higuchi, T; Katoh, M; Suzuyama, N; Takeuchi, T; Yokoi, T; Yoshitomi, S | 1 |
| Kaukonen, AM; Laitinen, L; Marvola, M; Takala, E; Vuorela, H; Vuorela, P | 1 |
| Gerloff, T; Roots, I; Schaefer, M | 1 |
| Cao, J; Chan, E; Chen, X; Huang, M; Li, XT; Liang, J; Sheu, FS; Wei, D; Wen, JY; Xu, AL; Yu, XQ; Yu, XY; Zhou, SF | 1 |
| Chen, X; Chowbay, B; Duan, W; Li, CG; Liang, J; Lin, SG; Liu, PQ; Wen, JY; Yu, XY; Zhou, SF; Zhou, ZW | 1 |
| Elston Lafata, J; Horn, JR; Kaatz, S; Raebel, MA; Schultz, L; Simpkins, J; Smith, DH; Yood, MU | 1 |
| Kataoka, Y; Machida, S; Masuda, K | 1 |
| Fan, G; Gao, S; Hong, Z; Xu, YA | 1 |
| Hellum, BH; Nilsen, OG | 1 |
| Baskurt, M; Kaya, A; Kucukoglu, S; Okcun, B; Ortak, K; Yigit, Z; Yildiz, A | 1 |
| Engdal, S; Nilsen, OG | 1 |
| Hansen, TS; Nilsen, OG | 1 |
| Djuv, A; Nilsen, OG | 1 |
| Balimane, PV; Chong, S; Marino, A | 1 |
| Jaggi, AS; Kaur, S; Rehni, AK; Singh, N | 1 |
| Kamiyama, E; Miura, S; Nakai, D; Okazaki, O; Sugiyama, D | 1 |
| Anzai, N; Endou, H; Jutabha, P; Kadota, T; Otomo, J; Wempe, MF | 1 |
| Georg Nilsen, O; Hellum, BH; Hoybakk, K; Rohloff, J; Thomsen, M; Tosse, A | 1 |
| Kamiyama, E; Mikkaichi, T; Nakai, D; Okazaki, O; Okudaira, N | 1 |
| Ai, H; Gu, Y; Hao, G; Li, Y; Peng, Y; Sun, J; Wang, G; Wu, X; Zhang, J; Zhang, X; Zheng, Y; Zhou, F | 1 |
| Al-Bataineh, MM; Gehring, R; Schultz, BD; van der Merwe, D | 1 |
| Döring, B; Geyer, J; Hambruch, N; Pfarrer, C; Tinneberg, HR; Waterkotte, B | 1 |
| Kawazu, K; Kiuchi, Y; Miyazaki, T; Oyabu, M; Toda, R | 1 |
| Li, N; Liu, Z; Ma, J; Sui, Z; Tsao, R | 1 |
| Ates, M; Aylin Arici, M; Demir, O; Gelal, A; Kilinc, E; Yesilyurt, A | 1 |
| Amad, M; Batonga, J; Bethell, RC; Bolger, G; Cordingley, MG; Duan, J; Garneau, M; Jutras, M; Kukolj, G; Lapeyre, N; Montpetit, H; Otis, F; Rhéaume, M; White, PW | 1 |
| Drożdż, J; Filipiak, KJ; Grajek, S; Kasprzak, JD; Opolski, G; Rynkiewicz, A; Stępińska, J; Tykarski, A; Wożakowska Kapłon, B | 1 |
| Baciewicz, AM; Chrisman, CR; Finch, CK; Self, TH | 1 |
| Apel, A; Cohen, O; Mayan, H; Rachel, P | 1 |
| Akhtar, M; Alakkam, A; Alrefai, WA; Anbazhagan, AN; Dudeja, PK; Gill, RK; Kumar, A; Priyamvada, S; Saksena, S; Soni, V | 1 |
| Broedl, UC; Macha, S; Pinnetti, S; Rose, P; Schoene, K; Sennewald, R; Woerle, HJ | 1 |
| Baum, L; Chanteux, H; Kwan, P; Zhang, C; Zuo, Z | 1 |
| Barter, Z; Jamei, M; Neuhoff, S; Rostami-Hodjegan, A; Turner, DB; Yeo, KR | 1 |
| Guan, T; Hao, K; Liang, Y; Liu, Y; Rao, T; Wang, GJ; Wang, Y; Xie, L; Xing, L; Zhang, J; Zhou, L; Zhou, Y | 1 |
| Mehta, DC; Nicolazzo, JA; Short, JL | 1 |
| Carpini, GD; Ghanem, CI; Luquita, MG; Mottino, AD; Novak, A; Rubio, MC; Ruiz, ML | 1 |
| Benet, LZ; Estudante, M; Maya, M; Morais, JG; Soveral, G | 1 |
| Hu, ZY; Zhao, Y | 1 |
| Aspeslet, LJ; Foster, RT; Freitag, DG; Huizinga, RB; Larouche, R; Ling, SY; Mayo, PR | 1 |
| Hu, J; Li, X; Li, Y; Liu, Z; Sheng, L; Wang, B; Yang, S | 1 |
| Fujii, S; Hosoya, K; Kawazu, K; Setoguchi, C | 1 |
| Brenk, R; Efferth, T; Gruber, L; Kopp, B; Urban, E; Zehl, M; Zeino, M | 1 |
| Ando, A; Miyamoto, Y; Ohzone, Y; Sasago, S | 1 |
| Al-Enazy, S; Albekairi, NA; Ali, S; Rytting, E | 1 |
| Barnes, RW; Ledwitch, KV; Roberts, AG | 1 |
| Ebner, T; Ishiguro, N; Kishimoto, W; Ludwig-Schwellinger, E; Maeda, K; Sugiyama, Y | 1 |
| Akazawa, T; Ohtsuki, S; Tachikawa, M; Terasaki, T; Uchida, Y | 1 |
| Bando, K; Deguchi, J; Honda, Y; Watanabe, H; Yamada, T | 1 |
| Dong, L; Dong, YL; Li, XL; Liu, Y; Pan, M; Wang, ZY; Yin, XW | 1 |
| Abu-Amer, N; Farfel, Z; Karlish, SJD; Mayan, H; Priel, E | 1 |
| Bedak, O; Begic, E; Bradaric, H; Custovic, F; Durak-Nalbantic, A; Hodzic, E; Mujakovic, A; Prnjavorac, B; Zvizdic, F | 1 |
| Cho, HS; Jung, CR; Kang, HM; Lim, JH; Noh, KH; Park, D; Susztak, K | 1 |
| Fletcher, S; Gharanei, M; James, RS; Maddock, H; Wallis, R | 1 |
| Chan, LN; Chen, KF; Lin, YS | 1 |
| De Zwart, L; Evers, R; Yamazaki, S | 1 |
| Alshogran, OY; Ghraiybah, NFA; I Al-Azzam, S | 1 |
| Azimi, M; Brett, CM; Giacomini, CP; Giacomini, KM; Riselli, A; Silva, DB; Yee, SW | 1 |
30 review(s) available for verapamil and digoxin
| Article | Year |
|---|---|
Membrane transporters in drug development.
Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs | 2010 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Prevention of supraventricular arrhythmias after coronary artery bypass surgery. A meta-analysis of randomized control trials.
Topics: Adrenergic beta-Antagonists; Arrhythmias, Cardiac; Coronary Artery Bypass; Digoxin; Humans; Meta-Analysis as Topic; Odds Ratio; Verapamil | 1991 |
Interference by antiarrhythmic agents with function of electrical cardiac devices.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Death, Sudden, Cardiac; Digoxin; Drug Interactions; Electric Countershock; Female; Flecainide; Humans; Male; Middle Aged; Pacemaker, Artificial; Prostheses and Implants; Verapamil; Warfarin | 1992 |
[Interaction between calcium antagonists and digoxin].
Topics: Atrial Fibrillation; Calcium Channel Blockers; Digoxin; Diltiazem; Drug Interactions; Humans; Nifedipine; Verapamil | 1991 |
[Mechanisms of interactions of anti-arrhythmia agents during their combined use].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Potassium; Procainamide; Propranolol; Quinidine; Verapamil | 1991 |
[Hydrops fetalis in tachycardia: diagnostic and therapeutic procedures].
Topics: Adult; Digoxin; Drug Therapy, Combination; Female; Heart Failure; Heart Rate, Fetal; Humans; Hydrops Fetalis; Infant, Newborn; Pregnancy; Pregnancy Trimester, Third; Tachycardia, Supraventricular; Verapamil | 1990 |
Cardiac arrhythmias in the elderly: antiarrhythmic drug treatment.
Topics: Aged; Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Procainamide; Propranolol; Quinidine; Tocainide; Verapamil | 1986 |
Calcium channel blocking agents and the heart.
Topics: Angina Pectoris; Arrhythmias, Cardiac; Calcium Channel Blockers; Coronary Vasospasm; Digoxin; Diltiazem; Heart Block; Heart Diseases; Heart Rate; Humans; Hypertension; Nifedipine; Verapamil | 1985 |
[Long-term drug therapy of reciprocating supraventricular tachycardia: re-examination of a selected series of cases, using computerized programs].
Topics: Acebutolol; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Child; Computers; Digoxin; Humans; Medigoxin; Middle Aged; Oxprenolol; Propafenone; Propiophenones; Sotalol; Tachycardia; Verapamil | 1980 |
[Therapy of arrhythmia during pregnancy].
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biotransformation; Coumarins; Digoxin; Drug Synergism; Female; Fetal Growth Retardation; Fetus; Heparin; Humans; Infant, Newborn; Milk, Human; Pacemaker, Artificial; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Quinidine; Verapamil | 1984 |
[Medical treatment of extrasystole and tachycardia (author's transl)].
Topics: Action Potentials; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Bretylium Compounds; Calcium; Cardiac Complexes, Premature; Digoxin; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Phenytoin; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1980 |
Digitalis toxicity: a review of the literature.
Topics: Absorption; Arrhythmias, Cardiac; Digitalis Glycosides; Digoxin; Heart; Humans; Kinetics; Male; Nifedipine; Probability; Verapamil | 1984 |
Verapamil and digoxin: their respective effects on atrial fibrillation and their interaction.
Topics: Action Potentials; Administration, Oral; Atrial Fibrillation; Atrioventricular Node; Autonomic Nervous System; Digitalis Glycosides; Digoxin; Drug Interactions; Exercise Test; Heart Failure; Verapamil; Wolff-Parkinson-White Syndrome | 1982 |
Management of rapid ventricular rate in acute atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Heart Rate; Humans; Propranolol; Verapamil; Wolff-Parkinson-White Syndrome | 1994 |
Management of atrial fibrillation in adults: prevention of thromboembolism and symptomatic treatment.
Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Aspirin; Atrial Fibrillation; Catheter Ablation; Cerebrovascular Disorders; Diabetes Complications; Digoxin; Diltiazem; Embolism; Humans; Hypertension; Thromboembolism; Verapamil; Warfarin | 1996 |
Toxic digoxin-drug interactions: the major role of renal P-glycoprotein.
Topics: Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Cyclosporine; Digoxin; Drug Interactions; Glomerular Filtration Rate; Humans; Itraconazole; Kidney Tubules; Quinidine; Verapamil | 1998 |
Atrial fibrillation: what are the effects of drug therapy on the effectiveness and complications of electrical cardioversion?
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Combined Modality Therapy; Digoxin; Electric Countershock; Flecainide; Humans; Procainamide; Quinidine; Verapamil | 1998 |
P-glycoprotein system as a determinant of drug interactions: the case of digoxin-verapamil.
Topics: Animals; Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cardiotonic Agents; Digoxin; Drug Interactions; Drug Resistance, Multiple; Heart Failure; Humans; Verapamil | 1999 |
The evidence regarding the drugs used for ventricular rate control.
Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Atrial Fibrillation; Bias; Calcium Channel Blockers; Digoxin; Diltiazem; Evidence-Based Medicine; Exercise; Heart Rate; Humans; Research Design; Rest; Treatment Outcome; Ventricular Function; Verapamil | 2000 |
Pharmacologic management of atrial fibrillation: current therapeutic strategies.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channel Blockers; Chronic Disease; Digoxin; Dihydropyridines; Drug Administration Routes; Electrocardiography; Embolism; Heart Rate; Humans; Practice Guidelines as Topic; Prognosis; Propranolol; Secondary Prevention; Tachycardia, Paroxysmal; Verapamil | 2001 |
Acute atrial fibrillation.
Topics: Acute Disease; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Electrocardiography; Fibrinolytic Agents; Humans; Prognosis; Randomized Controlled Trials as Topic; Thromboembolism; Timolol; Treatment Outcome; Verapamil | 2002 |
Pharmacological rate control of atrial fibrillation.
Topics: Amiodarone; Atenolol; Atrial Fibrillation; Cardiotonic Agents; Digoxin; Diltiazem; Heart Rate; Humans; Metoprolol; Randomized Controlled Trials as Topic; Verapamil | 2004 |
Potential interactions between exercise and drug therapy.
Topics: Absorption; Acetaminophen; Adrenergic beta-Antagonists; Aspirin; Digoxin; Doxycycline; Exercise; Humans; Insulin; Pharmacokinetics; Theophylline; Tissue Distribution; Verapamil; Warfarin | 2004 |
Atrial fibrillation (acute).
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Humans; Timolol; Verapamil | 2003 |
Atrial fibrillation (acute).
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Flecainide; Humans; Propafenone; Timolol; Verapamil | 2003 |
Atrial fibrillation (acute).
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Flecainide; Humans; Propafenone; Verapamil | 2004 |
Atrial fibrillation (recent onset).
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Diltiazem; Flecainide; Humans; Propafenone; Verapamil | 2005 |
[Pharmaceutical support in the cardiovascular and cardiovascular surgery ward].
Topics: Aged; Anti-Bacterial Agents; Cardiology Service, Hospital; Cefazolin; Coronary Artery Bypass, Off-Pump; Digoxin; Drug Information Services; Drug Interactions; Drug Therapy, Combination; Female; Heart Valve Diseases; Humans; Male; Middle Aged; Pharmacy Service, Hospital; Risk Factors; Surgical Wound Infection; Verapamil | 2007 |
Update on rifampin, rifabutin, and rifapentine drug interactions.
Topics: Anti-Arrhythmia Agents; Antibiotics, Antitubercular; Anticholesteremic Agents; Antifungal Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Contraceptives, Oral; Cytochrome P-450 Enzyme System; Digoxin; Drug Interactions; HIV Protease Inhibitors; Humans; Itraconazole; Rifabutin; Rifampin; Simvastatin; Verapamil | 2013 |
37 trial(s) available for verapamil and digoxin
| Article | Year |
|---|---|
[Clinical experience in the treatment of cardiac insufficiencies].
Topics: Biological Availability; Clinical Trials as Topic; Digoxin; Drug Combinations; Heart Failure; Humans; Verapamil | 1977 |
[Echocardiographic evaluation of left ventricular function during therapy with cardiovascularly effective drugs].
Topics: Digoxin; Echocardiography; Heart; Heart Failure; Heart Ventricles; Humans; Isoproterenol; Propranolol; Proscillaridin; Verapamil | 1976 |
Digoxin-verapamil interaction: reduction of biliary but not renal digoxin clearance in humans.
Topics: Bile; Biliary Tract; Digoxin; Drug Interactions; Female; Humans; Kidney; Male; Verapamil | 1991 |
Efficacy of flecainide acetate for atrial arrhythmias following coronary artery bypass grafting.
Topics: Adult; Aged; Arrhythmias, Cardiac; Coronary Artery Bypass; Digoxin; Drug Therapy, Combination; Female; Flecainide; Hemodynamics; Humans; Male; Middle Aged; Random Allocation; Verapamil | 1989 |
Esmolol versus verapamil in the acute treatment of atrial fibrillation or atrial flutter.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atrial Fibrillation; Atrial Flutter; Blood Pressure; Clinical Trials as Topic; Digoxin; Female; Heart Rate; Humans; Male; Middle Aged; Multicenter Studies as Topic; Propanolamines; Random Allocation; Verapamil | 1989 |
Digoxin or verapamil or metoprolol for heart rate control in patients with mitral stenosis--a randomised cross-over study.
Topics: Adult; Arrhythmia, Sinus; Atrial Fibrillation; Digoxin; Heart Rate; Humans; Metoprolol; Mitral Valve Stenosis; Random Allocation; Verapamil | 1989 |
Improved control of atrial fibrillation with combined pindolol and digoxin therapy.
Topics: Adult; Aged; Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Dyspnea; Female; Heart Rate; Humans; Middle Aged; Pindolol; Verapamil | 1989 |
The comparative effects of verapamil and a new dihydropyridine calcium channel blocker on digoxin pharmacokinetics.
Topics: Adolescent; Adult; Digoxin; Drug Interactions; Humans; Isradipine; Kinetics; Male; Pyridines; Random Allocation; Verapamil | 1987 |
Comparative effects of verapamil and isradipine on steady-state digoxin kinetics.
Topics: Adult; Calcium Channel Blockers; Digoxin; Drug Interactions; Heart Rate; Humans; Isradipine; Male; Pyridines; Verapamil | 1988 |
Factors affecting the clinical response to treatment with digoxin and two calcium antagonists in patients with atrial fibrillation.
Topics: Atrial Fibrillation; Calcium Channel Blockers; Clinical Trials as Topic; Digoxin; Diltiazem; Double-Blind Method; Heart Rate; Humans; Physical Exertion; Random Allocation; Rheumatic Heart Disease; Verapamil | 1988 |
Relationships between heart rate, exercise tolerance and cardiac output in atrial fibrillation: the effects of treatment with digoxin, verapamil and diltiazem.
Topics: Aged; Atrial Fibrillation; Cardiac Output; Chronic Disease; Digoxin; Diltiazem; Heart Rate; Humans; Middle Aged; Physical Exertion; Verapamil | 1988 |
Relative efficacy of oral verapamil and digoxin alone and in combination for the treatment of patients with chronic atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Chronic Disease; Clinical Trials as Topic; Digoxin; Double-Blind Method; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Middle Aged; Physical Exertion; Random Allocation; Verapamil | 1988 |
Towards improved control of atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Chronic Disease; Circadian Rhythm; Clinical Trials as Topic; Digoxin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Middle Aged; Random Allocation; Verapamil | 1987 |
A comparison of verapamil and digoxin in the treatment of atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Chronic Disease; Clinical Trials as Topic; Digoxin; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Verapamil | 1987 |
Effect of calcium antagonists on basal and digitalis-dependent changes in splanchnic and systemic hemodynamics.
Topics: Adult; Digoxin; Drug Interactions; Hemodynamics; Humans; Injections, Intravenous; Liver Circulation; Male; Propylamines; Splanchnic Circulation; Tiapamil Hydrochloride; Verapamil | 1987 |
[Gradulon in the treatment of heart insufficiency with simultaneous cardiocirculatory load].
Topics: Adult; Benzoates; Cardiovascular System; Clinical Trials as Topic; Digoxin; Drug Combinations; Drug Evaluation; Heart Failure; Humans; Male; Middle Aged; Morpholines; Tranquilizing Agents; Verapamil | 1974 |
Digoxin plasma concentrations and nifedipine.
Topics: Adult; Aged; Clinical Trials as Topic; Digoxin; Double-Blind Method; Drug Interactions; Humans; Middle Aged; Nifedipine; Pyridines; Random Allocation; Verapamil | 1981 |
Superiority of oral verapamil therapy to digoxin in treatment of chronic atrial fibrillation.
Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Clinical Trials as Topic; Digoxin; Drug Therapy, Combination; Exercise Test; Female; Half-Life; Heart Rate; Humans; Male; Middle Aged; Time Factors; Verapamil | 1983 |
Effectiveness and safety of oral verapamil to control exercise-induced tachycardia in patients with atrial fibrillation receiving digitalis.
Topics: Administration, Oral; Adult; Aged; Atrial Fibrillation; Atrial Flutter; Chronic Disease; Clinical Trials as Topic; Digitalis; Digoxin; Double-Blind Method; Female; Humans; Male; Middle Aged; Physical Exertion; Placebos; Plants, Medicinal; Plants, Toxic; Random Allocation; Tachycardia; Verapamil | 1983 |
Long-term therapy of paroxysmal supraventricular tachycardia: a randomized, double-blind comparison of digoxin, propranolol and verapamil.
Topics: Adult; Aged; Clinical Trials as Topic; Digoxin; Double-Blind Method; Female; Humans; Male; Middle Aged; Propranolol; Random Allocation; Tachycardia, Paroxysmal; Verapamil | 1984 |
Effect of coadministration of verapamil and quinidine on serum digoxin concentration.
Topics: Adult; Digoxin; Drug Combinations; Drug Interactions; Electrocardiography; Heart Rate; Humans; Middle Aged; Quinidine; Verapamil | 1983 |
Radionuclide evaluation of CHF.
Topics: Adolescent; Adult; Coronary Disease; Digoxin; Female; Heart Aneurysm; Heart Failure; Hemodynamics; Humans; Male; Middle Aged; Myocardial Infarction; Nitroglycerin; Propranolol; Radionuclide Imaging; Technetium; Theophylline; Verapamil | 1981 |
Verapamil improves exercise capacity in chronic atrial fibrillation: double-blind crossover study.
Topics: Adult; Aged; Atrial Fibrillation; Blood Pressure; Digoxin; Double-Blind Method; Exercise Test; Female; Heart Rate; Humans; Male; Middle Aged; Physical Exertion; Prospective Studies; Random Allocation; Verapamil | 1983 |
[Behaviour of serum CPK curves in acute myocardial infarction treated with digitalis, verapamil and combined verapamil-digitalis (author's transl)].
Topics: Adult; Aged; Clinical Enzyme Tests; Creatine Kinase; Digoxin; Female; Glucose; Humans; Insulin; Male; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Potassium; Verapamil | 1981 |
Verapamil therapy of atrial fibrillation and atrial flutter following cardiac operation.
Topics: Adult; Aged; Atrial Fibrillation; Atrial Flutter; Blood Pressure; Cardiac Surgical Procedures; Clinical Trials as Topic; Digoxin; Drug Interactions; Female; Humans; Male; Middle Aged; Verapamil | 1982 |
Treatment of chronic atrial fibrillation in the elderly, assessed by ambulatory electrocardiographic monitoring.
Topics: Aged; Atrial Fibrillation; Digoxin; Drug Tolerance; Electrocardiography; Evaluation Studies as Topic; Female; Heart Rate; Humans; Male; Middle Aged; Pindolol; Placebos; Verapamil | 1980 |
Mixed-effect modeling for detection and evaluation of drug interactions: digoxin-quinidine and digoxin-verapamil combinations.
Topics: Adult; Aged; Aged, 80 and over; Aging; Anti-Arrhythmia Agents; Body Weight; Calcium Channel Blockers; Computer Simulation; Creatinine; Digoxin; Drug Combinations; Drug Interactions; Female; Humans; Male; Middle Aged; Models, Biological; Quinidine; Regression Analysis; Verapamil | 1996 |
Effectiveness of verapamil-quinidine versus digoxin-quinidine in the emergency department treatment of paroxysmal atrial fibrillation.
Topics: Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Double-Blind Method; Drug Therapy, Combination; Emergency Medical Services; Emergency Service, Hospital; Female; Humans; Male; Middle Aged; Prospective Studies; Quinidine; Tachycardia, Paroxysmal; Treatment Outcome; Verapamil | 1997 |
Modulation of ventricular rate in permanent atrial fibrillation: randomized, crossover study of the effects of slow-release formulations of gallopamil, diltiazem, or verapamil.
Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channel Blockers; Cardiotonic Agents; Cross-Over Studies; Delayed-Action Preparations; Digoxin; Diltiazem; Electrocardiography, Ambulatory; Female; Gallopamil; Heart Rate; Humans; Male; Middle Aged; Verapamil | 1998 |
Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion.
Topics: Adolescent; Adult; Anticholesteremic Agents; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Heptanoic Acids; Humans; Intestinal Mucosa; Male; Middle Aged; Pyrroles; Time Factors; Verapamil | 2000 |
VERDICT: the Verapamil versus Digoxin Cardioversion Trial: A randomized study on the role of calcium lowering for maintenance of sinus rhythm after cardioversion of persistent atrial fibrillation.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium; Calcium Channel Blockers; Digoxin; Electric Countershock; Electrocardiography, Ambulatory; Female; Heart Rate; Humans; Male; Middle Aged; Prospective Studies; Treatment Outcome; Verapamil | 2001 |
Clinical assessment of clonidine in the treatment of new-onset rapid atrial fibrillation: a prospective, randomized clinical trial.
Topics: Acute Disease; Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Blood Pressure; Clonidine; Digoxin; Female; Heart Rate; Humans; Infusions, Intravenous; Male; Middle Aged; Prospective Studies; Treatment Outcome; Verapamil | 2001 |
Sinus rhythm maintenance following DC cardioversion of atrial fibrillation is not improved by temporary precardioversion treatment with oral verapamil.
Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Electric Countershock; Female; Humans; Male; Treatment Outcome; Verapamil | 2004 |
Verapamil versus digoxin and acute versus routine serial cardioversion for the improvement of rhythm control for persistent atrial fibrillation.
Topics: Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium; Digoxin; Electric Countershock; Female; Hemorrhage; Humans; Male; Middle Aged; Prospective Studies; Quality of Life; Recurrence; Thromboembolism; Treatment Outcome; Verapamil | 2006 |
Comparison of rate and rhythm control in hypertension patients with atrial fibrillation.
Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Atrial Fibrillation; Calcium Channel Blockers; Cardiotonic Agents; Digoxin; Electric Countershock; Female; Follow-Up Studies; Humans; Hypertension; Losartan; Male; Metoprolol; Middle Aged; Survival Analysis; Treatment Outcome; Verapamil | 2008 |
Lack of clinically relevant drug-drug interaction between empagliflozin, a sodium glucose cotransporter 2 inhibitor, and verapamil, ramipril, or digoxin in healthy volunteers.
Topics: Adolescent; Adult; Area Under Curve; Benzhydryl Compounds; Cross-Over Studies; Digoxin; Drug Interactions; Female; Glucosides; Half-Life; Humans; Male; Middle Aged; Ramipril; Reference Values; Sodium-Glucose Transporter 2; Sodium-Glucose Transporter 2 Inhibitors; Verapamil; Young Adult | 2013 |
Cytochrome P450 3A and P-glycoprotein drug-drug interactions with voclosporin.
Topics: Adolescent; Adult; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcineurin Inhibitors; Cyclosporine; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Drug Interactions; Female; Humans; Ketoconazole; Male; Midazolam; Middle Aged; Verapamil | 2014 |
270 other study(ies) available for verapamil and digoxin
| Article | Year |
|---|---|
Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein.
Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Caco-2 Cells; Cell Membrane Permeability; Dose-Response Relationship, Drug; Humans; Hydrolysis; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Models, Biological; Pharmaceutical Preparations; Swine; Tissue Distribution; Transfection | 2001 |
Comparative inhibitory effects of different compounds on rat oatpl (slc21a1)- and Oatp2 (Slc21a5)-mediated transport.
Topics: Algorithms; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibiotics, Antitubercular; Antimalarials; Biological Transport, Active; Digoxin; Enzyme Inhibitors; Estradiol; Ibuprofen; LLC-PK1 Cells; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Organic Cation Transport Proteins; Quinidine; Quinine; Rats; Rifampin; Swine | 2002 |
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Drug Evaluation, Preclinical; Fluoresceins; Fluorescent Dyes; Humans; Indicators and Reagents; Mice; Models, Molecular; Rhodamines; Species Specificity; Swine | 2003 |
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Cells, Cultured; Diffusion; Humans; Intestinal Absorption; Intestinal Mucosa; Models, Biological; Permeability; Pharmaceutical Preparations; Pharmacokinetics | 2003 |
Variable modulation of opioid brain uptake by P-glycoprotein in mice.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Benzomorphans; Biological Transport; Brain; Drug Interactions; Fentanyl; Loperamide; Meperidine; Methadone; Mice; Narcotics; Quinidine; Time Factors; Verapamil | 2004 |
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties | 2004 |
Predicting P-glycoprotein effects on oral absorption: correlation of transport in Caco-2 with drug pharmacokinetics in wild-type and mdr1a(-/-) mice in vivo.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport, Active; Caco-2 Cells; Cell Membrane Permeability; Humans; Intestinal Absorption; Mice; Mice, Knockout; Pharmacokinetics; Spectrometry, Mass, Electrospray Ionization | 2004 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Attenuation of intestinal absorption by major efflux transporters: quantitative tools and strategies using a Caco-2 model.
Topics: Adenosine; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Chromatography, Liquid; Dibenzocycloheptenes; Diketopiperazines; Drug Discovery; Heterocyclic Compounds, 4 or More Rings; Humans; Intestinal Absorption; Mass Spectrometry; Models, Biological; Neoplasm Proteins; Pharmaceutical Preparations; Predictive Value of Tests; Propionates; Quinolines; Substrate Specificity | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Effects of chronic renal failure on brain drug transporters in rats.
Topics: Animals; Biological Transport, Active; Blood-Brain Barrier; Brain; Cells, Cultured; Kidney Failure, Chronic; Male; Membrane Transport Proteins; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Design, Synthesis, and Biological Evaluation of 2-Nitroimidazopyrazin-one/-es with Antitubercular and Antiparasitic Activity.
Topics: Animals; Antiparasitic Agents; Antitubercular Agents; Caco-2 Cells; Drug Design; Drug Evaluation, Preclinical; Drug Stability; Entamoeba histolytica; Giardia lamblia; Humans; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Nitroimidazoles; Structure-Activity Relationship | 2018 |
Heteroaryl Phosphonates as Noncovalent Inhibitors of Both Serine- and Metallocarbapenemases.
Topics: Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamase Inhibitors; beta-Lactamases; beta-Lactams; Crystallography, X-Ray; Drug Design; Enterobacter cloacae; Escherichia coli; HEK293 Cells; Humans; Imipenem; Klebsiella pneumoniae; Ligands; Microsomes, Liver; Molecular Conformation; Organophosphonates; Pseudomonas aeruginosa | 2019 |
Class I/IIb-Selective HDAC Inhibitor Exhibits Oral Bioavailability and Therapeutic Efficacy in Acute Myeloid Leukemia.
Topics: | 2020 |
Development of an
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Cell Line; Computer Simulation; Endothelial Cells; Gene Knockout Techniques; Humans; Organic Chemicals; Rats, Transgenic | 2021 |
Non-carboxylic acid inhibitors of aldose reductase based on N-substituted thiazolidinedione derivatives.
Topics: Aldehyde Reductase; Animals; Caco-2 Cells; Catalytic Domain; Dogs; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Madin Darby Canine Kidney Cells; Male; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Protein Binding; Rats, Wistar; Structure-Activity Relationship; Thiazolidinediones | 2021 |
Discovery, Structure-Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain.
Topics: Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Caco-2 Cells; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Microsomes, Liver; Molecular Structure; Neuralgia; Protein Kinases; Protein Serine-Threonine Kinases; Structure-Activity Relationship | 2021 |
The treatment of supraventricular arrhythmias.
Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmia, Sinus; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Cardiac Pacing, Artificial; Digoxin; Disopyramide; Electric Countershock; Humans; Phenytoin; Procainamide; Quinidine; Tachycardia; Tachycardia, Paroxysmal; Verapamil | 1979 |
[Echocardiography during the therapy of cardiovascular diseases].
Topics: Calcium Chloride; Digoxin; Echocardiography; Heart Diseases; Heart Ventricles; Humans; Isoproterenol; Propranolol; Proscillaridin; Verapamil | 1977 |
The management of the patient with angina.
Topics: Angina Pectoris; Anticoagulants; Clofibrate; Coronary Artery Bypass; Diazepam; Digoxin; Humans; Isosorbide Dinitrate; Nitroglycerin; Oxprenolol; Perhexiline; Prenylamine; Propranolol; Verapamil | 1977 |
The beneficial effects of verapamil in chronic atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Chronic Disease; Digoxin; Female; Heart Rate; Humans; Male; Middle Aged; Physical Exertion; Verapamil | 1979 |
The influence of calcium antagonists on the maximum inotropic effect on and the toxicity of digoxin and digitoxin in the isolated electrically driven guinea pig atrium.
Topics: Animals; Calcium; Carbachol; Digitoxin; Digoxin; Drug Interactions; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Verapamil | 1977 |
[Myocardial excitability under the influence of digitalis glycosides and anti-arrhythmia agent].
Topics: Ajmaline; Anti-Arrhythmia Agents; Digitalis Glycosides; Digoxin; Heart Conduction System; Humans; Lidocaine; Myocardial Contraction; Phenytoin; Procainamide; Propranolol; Refractory Period, Electrophysiological; Stimulation, Chemical; Verapamil | 1977 |
Plasma digoxin concentrations in patients with atrial fibrillation and indications for the association with other antiarrhythmic agents.
Topics: Aged; Atrial Fibrillation; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Middle Aged; Practolol; Time Factors; Verapamil | 1977 |
Drugs of choice for atrial tachycardia.
Topics: Administration, Oral; Digitalis Glycosides; Digoxin; Edrophonium; Humans; Lanatosides; Metaraminol; Neostigmine; Parasympathomimetics; Propranolol; Quinidine; Tachycardia; Verapamil | 1975 |
[Treatment of heart-rhythm disorders in infancy and childhood].
Topics: Age Factors; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Child; Child, Preschool; Digoxin; Electric Countershock; Heart Block; Humans; Infant; Metaproterenol; Pacemaker, Artificial; Tachycardia; Verapamil | 1975 |
Transport of digoxin by human P-glycoprotein expressed in a porcine kidney epithelial cell line (LLC-PK1).
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Line; Digoxin; Drug Interactions; Gene Expression; Humans; Kidney Tubules; Membrane Glycoproteins; Quinidine; Swine; Transfection; Verapamil | 1992 |
The MDR1 gene product, P-glycoprotein, mediates the transport of the cardiac glycoside, digoxin.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; CHO Cells; Colchicine; Cricetinae; Cyclosporine; Digoxin; Dose-Response Relationship, Drug; Drug Resistance; Kinetics; Membrane Glycoproteins; Quinidine; Verapamil; Vinblastine | 1992 |
[Clinical effectiveness of cordarone in combination with other anti-arrhythmia agents in refractory atrial fibrillation and adverse effects of the drugs].
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Humans; Middle Aged; Moricizine; Quinidine; Verapamil | 1992 |
Cardiac glycosides in the treatment of experimental overdose with calcium-blocking agents.
Topics: Animals; Atropine; Calcium; Calcium Channel Blockers; Calcium Gluconate; Depression, Chemical; Digoxin; Diltiazem; Dogs; Drug Overdose; Electrocardiography; Female; Hemodynamics; Humans; Male; Myocardium; Verapamil | 1992 |
[The chronotropic and hemodynamic effects of finoptin in patients with a permanent form of atrial fibrillation].
Topics: Adult; Aged; Aged, 80 and over; Atrial Fibrillation; Chronic Disease; Digoxin; Drug Evaluation; Drug Therapy, Combination; Female; Heart Rate; Hemodynamics; Humans; Male; Middle Aged; Verapamil | 1992 |
Inhibition by basic drugs of digoxin secretion into human bile.
Topics: Bile; Chromatography, High Pressure Liquid; Digoxin; Drug Interactions; Humans; Probenecid; Quinidine; Quinine; Radioimmunoassay; Spironolactone; Verapamil | 1992 |
Stability of amrinone and digoxin, procainamide hydrochloride, propranolol hydrochloride, sodium bicarbonate, potassium chloride, or verapamil hydrochloride in intravenous admixtures.
Topics: Amrinone; Bicarbonates; Chromatography, High Pressure Liquid; Digoxin; Drug Combinations; Drug Incompatibility; Drug Stability; Potassium Chloride; Procainamide; Propranolol; Sodium; Sodium Bicarbonate; Verapamil | 1991 |
Amiodarone, verapamil, and quinidine do not affect equilibrium binding of digoxin.
Topics: Amiodarone; Animals; Binding, Competitive; Digoxin; Dogs; Myocardium; Quinidine; Receptors, Drug; Sarcolemma; Sodium-Potassium-Exchanging ATPase; Verapamil | 1990 |
Acute effects of commonly used drugs in the cardiac care unit on the myocardial extraction kinetics of 99mTc-Sestamibi.
Topics: Animals; Coronary Care Units; Coronary Disease; Digoxin; Dipyridamole; Drug Interactions; Guinea Pigs; Heart; Male; Myocardium; Organotechnetium Compounds; Swine; Swine, Miniature; Technetium Tc 99m Sestamibi; Verapamil | 1991 |
Effects of digoxin, propranolol, and verapamil on exercise in patients with chronic isolated atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Chronic Disease; Digoxin; Exercise; Heart Rate; Humans; Male; Middle Aged; Oxygen Consumption; Propranolol; Verapamil | 1991 |
Relationship between systemic and coronary vascular responses to digoxin and concurrent drug therapy with verapamil/beta-adrenoceptor antagonists in humans.
Topics: Adrenergic beta-Antagonists; Adult; Cardiac Catheterization; Coronary Disease; Coronary Vessels; Digoxin; Drug Therapy, Combination; Female; Hemodynamics; Humans; Male; Middle Aged; Vascular Resistance; Verapamil | 1990 |
[Successful intrauterine treatment of a supraventricular tachycardia-induced hydrops fetalis with digoxin and verapamil].
Topics: Digoxin; Drug Administration Schedule; Drug Therapy, Combination; Electrocardiography; Female; Fetal Blood; Heart Rate, Fetal; Humans; Hydrops Fetalis; Infant, Newborn; Infusions, Intravenous; Pregnancy; Prenatal Diagnosis; Tachycardia, Supraventricular; Verapamil | 1991 |
Electrocardiogram of the month.
Topics: Arrhythmias, Cardiac; Atrioventricular Node; Digoxin; Electrocardiography; Humans; Male; Middle Aged; Verapamil | 1990 |
Supraventricular tachycardia in infants: response to initial treatment.
Topics: Adenosine; Digoxin; Electric Countershock; Humans; Hypothermia, Induced; Infant; Infant, Newborn; Prognosis; Retrospective Studies; Tachycardia, Supraventricular; Verapamil | 1990 |
Verapamil-digoxin interaction in chronic hemodialysis patients.
Topics: Adult; Digoxin; Drug Interactions; Humans; Kidney Failure, Chronic; Renal Dialysis; Verapamil | 1990 |
Epicardial electrical activation analyzed via frequency-wavenumber spectrum estimation for the characterization of arrhythmiagenic states.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Coronary Disease; Coronary Vessels; Digoxin; Dogs; Electrocardiography; Heart; Ion Channels; Membrane Potentials; Signal Processing, Computer-Assisted; Time Factors; Verapamil | 1987 |
Effect of digoxin on the extent of injury and the severity of arrhythmias during acute myocardial ischemia and infarction in the dog.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Digoxin; Dogs; Electrocardiography; Heart Rate; Heart Ventricles; Infusions, Intravenous; Lidocaine; Male; Myocardial Infarction; Verapamil | 1988 |
The mechanisms of exercise provocation of supraventricular tachycardia.
Topics: Adrenergic beta-Agonists; Adult; Aged; Aged, 80 and over; Digoxin; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Exercise; Exercise Test; Female; Humans; Isoproterenol; Male; Middle Aged; Tachycardia, Supraventricular; Verapamil | 1989 |
[The family physician and drug side-effects. Observations from general practice--conclusions for general practice].
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Cosyntropin; Diclofenac; Digoxin; Drug Eruptions; Drug Hypersensitivity; Drug Interactions; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Injections, Intramuscular; Male; Middle Aged; Nitrofurantoin; Penicillin G Procaine; Risk Factors; Verapamil | 1989 |
Repeated intravascular treatment with amiodarone in a fetus with refractory supraventricular tachycardia and hydrops fetalis.
Topics: Adult; Amiodarone; Digoxin; Female; Fetal Diseases; Humans; Hydrops Fetalis; Injections, Intravenous; Pregnancy; Pregnancy Outcome; Recurrence; Tachycardia, Supraventricular; Umbilical Veins; Verapamil | 1989 |
Digoxin-stimulated calcium transport across rat diaphragm interactions with aminophylline and verapamil.
Topics: Aminophylline; Animals; Calcium; Diaphragm; Digoxin; Female; In Vitro Techniques; Male; Rats; Rats, Inbred Strains; Respiratory Muscles; Verapamil | 1989 |
[The efficacy of calcium antagonists in circulatory failure in elderly patients with hypertension].
Topics: Aged; Calcium Channel Blockers; Digoxin; Dose-Response Relationship, Drug; Drug Evaluation; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Nifedipine; Time Factors; Verapamil | 1989 |
[The use of digoxin, lasix and finoptin in treating circulatory failure in hypertension].
Topics: Aged; Aldosterone; Digoxin; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Humans; Hypertension; Male; Middle Aged; Nucleotides, Cyclic; Potassium; Renin; Sodium; Verapamil | 1989 |
[Pharmacologic restoration of sinus rhythm in atrial flutter and fibrillation].
Topics: Atrial Fibrillation; Atrial Flutter; Digoxin; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Middle Aged; Quinidine; Verapamil | 1989 |
Age-related digoxin-verapamil interactions in the adult rat.
Topics: Aging; Animals; Digoxin; Drug Interactions; Electrocardiography; Heart Rate; Male; Rats; Rats, Inbred Strains; Tachycardia; Verapamil | 1989 |
[Effect of digoxin, furosemide and finoptin on the central hemodynamics in hypertension].
Topics: Aged; Chronic Disease; Digoxin; Drug Evaluation; Drug Therapy, Combination; Female; Furosemide; Heart Failure; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Verapamil | 1989 |
Cardiogenic shock associated with calcium-channel and beta blockers: reversal with intravenous calcium chloride.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Atenolol; Calcium Channel Blockers; Calcium Chloride; Digoxin; Diltiazem; Female; Humans; Isoproterenol; Male; Shock, Cardiogenic; Verapamil | 1985 |
Update on rifampin drug interactions.
Topics: Adrenergic beta-Antagonists; Cyclosporins; Digoxin; Drug Interactions; Humans; Ketoconazole; Phenytoin; Rifampin; Theophylline; Verapamil | 1987 |
Effects of nicorandil and verapamil, antianginal agents, on plasma digoxin concentrations in rats and dogs.
Topics: Animals; Blood Pressure; Digoxin; Dogs; Drug Interactions; Female; Heart Rate; Male; Niacinamide; Nicorandil; Rats; Rats, Inbred Strains; Vasodilator Agents; Verapamil | 1987 |
Hyperthyroid-induced atrial flutter-fibrillation with profound sinoatrial nodal pauses due to small doses of digoxin, verapamil, and propranolol.
Topics: Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Digoxin; Female; Humans; Hyperthyroidism; Middle Aged; Propranolol; Verapamil | 1989 |
Pindolol, not verapamil, in combination with digoxin is the treatment of choice in chronic atrial fibrillation.
Topics: Atrial Fibrillation; Chronic Disease; Digoxin; Drug Therapy, Combination; Humans; Pindolol; Verapamil | 1989 |
Fetal atrial flutter and X-linked dominant vitamin D-resistant rickets.
Topics: Adult; Atrial Flutter; Cesarean Section; Digoxin; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Female; Heart Failure; Humans; Hypophosphatemia, Familial; Infant, Newborn; Infant, Premature; Pregnancy; Prenatal Diagnosis; Ultrasonography; Verapamil | 1985 |
Treatment of paroxysmal supraventricular tachycardia in the emergency department by clinical decision analysis.
Topics: Adult; Aged; Aged, 80 and over; Decision Support Techniques; Digoxin; Electric Countershock; Emergencies; Emergency Service, Hospital; Female; Humans; Male; Middle Aged; Prospective Studies; Tachycardia, Supraventricular; Valsalva Maneuver; Verapamil | 1988 |
Reversible cardiomyopathy following chronic supraventricular tachycardia.
Topics: Adult; Cardiomyopathy, Dilated; Chronic Disease; Digoxin; Drug Combinations; Electrocardiography; Humans; Male; Tachycardia, Supraventricular; Ultrasonography; Verapamil | 1988 |
Fetal tachycardias.
Topics: Digoxin; Female; Fetal Diseases; Humans; Hydrops Fetalis; Pregnancy; Tachycardia; Verapamil | 1988 |
Comparative efficacy of Univer and conventional verapamil in the control of ventricular response in atrial fibrillation.
Topics: Aged; Atrial Fibrillation; Delayed-Action Preparations; Digoxin; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Verapamil | 1988 |
Cardiovascular collapse after verapamil in supraventricular tachycardia.
Topics: Digoxin; Drug Interactions; Humans; Hypotension; Propranolol; Tachycardia, Supraventricular; Verapamil | 1988 |
Cardiac arrest following i.v. verapamil may be related to concomitant digoxin therapy as well as halothane.
Topics: Digoxin; Drug Interactions; Halothane; Heart Arrest; Humans; Intraoperative Complications; Verapamil | 1988 |
Stability of milrinone and digoxin, furosemide, procainamide hydrochloride, propranolol hydrochloride, quinidine gluconate, or verapamil hydrochloride in 5% dextrose injection.
Topics: Digoxin; Drug Combinations; Drug Stability; Drug Storage; Furosemide; Glucose; Indicators and Reagents; Milrinone; Procainamide; Propranolol; Pyridones; Quinidine; Solutions; Temperature; Verapamil | 1988 |
Fetal death after successful conversion of fetal supraventricular tachycardia with digoxin and verapamil.
Topics: Adult; Digoxin; Drug Therapy, Combination; Female; Fetal Death; Fetal Diseases; Humans; Pregnancy; Tachycardia, Supraventricular; Verapamil | 1988 |
Obstetric importance, diagnosis, and management of fetal tachycardias.
Topics: Delivery, Obstetric; Digoxin; Drug Therapy, Combination; Edema; Female; Fetal Diseases; Heart Failure; Heart Rate, Fetal; Humans; Infant, Newborn; Maternal-Fetal Exchange; Pregnancy; Tachycardia; Verapamil | 1988 |
Vasoconstrictor effects of endogenous digitalis-like factors extracted from urine of hypertensive patients.
Topics: Animals; Arteries; Blood Proteins; Cardenolides; Digoxin; Dogs; Ear, External; Epinephrine; Humans; Hypertension; In Vitro Techniques; Mesenteric Arteries; Ouabain; Phentolamine; Potassium Chloride; Quinazolines; Saponins; Vasoconstrictor Agents; Verapamil | 1987 |
Verapamil-induced changes in digoxin kinetics in cirrhosis.
Topics: Adult; Aged; Digoxin; Drug Interactions; Female; Humans; Kinetics; Liver Cirrhosis; Middle Aged; Verapamil | 1987 |
Tissue distribution of digoxin in the presence of calcium channel blockers.
Topics: Animals; Calcium Channel Blockers; Digoxin; Diltiazem; Guinea Pigs; Male; Tissue Distribution; Verapamil | 1987 |
Interactions with cardioactive drugs.
Topics: Aged; Digoxin; Drug Interactions; Female; Humans; Tachycardia, Supraventricular; Verapamil | 1986 |
Congestive cardiomyopathy due to chronic tachycardia: resolution of cardiomyopathy with antiarrhythmic drugs.
Topics: Cardiomyopathy, Dilated; Child, Preschool; Digoxin; Drug Therapy, Combination; Electrocardiography; Humans; Male; Tachycardia, Supraventricular; Verapamil | 1987 |
Insufficient transplacental digoxin transfer in severe hydrops fetalis.
Topics: Adult; Digoxin; Edema; Female; Fetal Diseases; Humans; Maternal-Fetal Exchange; Pregnancy; Propranolol; Tachycardia, Supraventricular; Verapamil | 1987 |
Efficacy of verapamil in the conversion of supraventricular tachycardia in Singapore children.
Topics: Child; Child, Preschool; Digoxin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Male; Neostigmine; Propranolol; Tachycardia, Supraventricular; Verapamil | 1987 |
Chloral hydrate: a potential cause of arrhythmias.
Topics: Child; Child, Preschool; Chloral Hydrate; Digoxin; Female; Heart Defects, Congenital; Humans; Infant; Isoproterenol; Male; Postoperative Complications; Propranolol; Tachycardia; Verapamil | 1986 |
Verapamil and breast-feeding.
Topics: Adult; Breast Feeding; Digoxin; Female; Humans; Milk, Human; Verapamil | 1986 |
Treatment of atrial arrhythmias. Effectiveness of verapamil when preceded by calcium infusion.
Topics: Adolescent; Adult; Aged; Atrial Fibrillation; Atrial Flutter; Calcium Chloride; Digoxin; Drug Evaluation; Drug Interactions; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypotension; Infusions, Parenteral; Male; Middle Aged; Premedication; Verapamil | 1986 |
Intravenous diltiazem for the treatment of supraventricular tachycardia.
Topics: Adult; Atrioventricular Node; Benzazepines; Blood Pressure; Digoxin; Diltiazem; Female; Heart Rate; Humans; Infusions, Parenteral; Male; Middle Aged; Tachycardia, Paroxysmal; Verapamil | 1986 |
Clinical digoxin toxicity in the aged in association with co-administered verapamil. A report of two cases and review of the literature.
Topics: Aged; Digoxin; Drug Interactions; Female; Heart Diseases; Humans; Kinetics; Quinidine; Verapamil | 1986 |
Effectiveness of oral verapamil in controlling ventricular rate in patients with chronic atrial fibrillation receiving digoxin.
Topics: Adolescent; Adult; Atrial Fibrillation; Chronic Disease; Digoxin; Drug Therapy, Combination; Female; Heart Rate; Humans; Male; Middle Aged; Verapamil | 1986 |
Intrauterine conversion of fetal supraventricular tachycardia with combination of digoxin and verapamil.
Topics: Administration, Oral; Adult; Digoxin; Drug Therapy, Combination; Echocardiography; Female; Fetal Diseases; Humans; Injections, Intravenous; Maternal-Fetal Exchange; Pregnancy; Tachycardia; Verapamil | 1985 |
Digoxin interactions. The influence of quinidine and verapamil on the pharmacokinetics and receptor binding of digitalis glycosides.
Topics: Animals; Digitalis Glycosides; Digoxin; Drug Interactions; Humans; Kinetics; Quinidine; Receptors, Drug; Sodium-Potassium-Exchanging ATPase; Verapamil | 1985 |
Treatment of fetal cardiac arrhythmias.
Topics: Amiodarone; Arrhythmia, Sinus; Arrhythmias, Cardiac; Chromosome Aberrations; Chromosome Disorders; Diagnosis, Differential; Digoxin; Drug Therapy, Combination; Echocardiography; Edema, Cardiac; Female; Fetal Diseases; Fetal Growth Retardation; Fetal Heart; Gestational Age; Heart Rate; Humans; Karyotyping; Lung; Maternal-Fetal Exchange; Pregnancy; Procainamide; Prognosis; Propranolol; Quinidine; Ultrasonography; Vena Cava, Superior; Verapamil | 1985 |
[Prenatal echographic diagnosis of fetoplacental anasarca].
Topics: Adult; Digoxin; Edema; Female; Fetal Diseases; Humans; Pregnancy; Tachycardia; Ultrasonography; Verapamil | 1985 |
Two-dimensional and M-mode echocardiographic evaluation of fetal arrhythmia.
Topics: Adult; Arrhythmias, Cardiac; Digoxin; Echocardiography; Female; Fetal Diseases; Follow-Up Studies; Humans; Pregnancy; Verapamil | 1985 |
Supraventricular tachycardias in the emergency room.
Topics: Atrial Fibrillation; Atrial Flutter; Digoxin; Edrophonium; Electric Countershock; Emergencies; Humans; Pressure; Propranolol; Tachycardia, Paroxysmal; Verapamil; Wolff-Parkinson-White Syndrome | 1985 |
Refractory supraventricular tachycardia in the neonate: treatment with temporary antitachycardial pacing.
Topics: Cardiac Pacing, Artificial; Combined Modality Therapy; Digoxin; Drug Therapy, Combination; Electric Countershock; Electrocardiography; Humans; Infant, Newborn; Male; Quinidine; Recurrence; Tachycardia, Paroxysmal; Verapamil | 1985 |
Plasma and tissue levels of digoxin in the rat following pretreatment with verapamil.
Topics: Animals; Digoxin; Drug Interactions; Injections, Intraperitoneal; Injections, Subcutaneous; Kinetics; Male; Rats; Tissue Distribution; Verapamil | 1985 |
Interaction between digoxin and commonly coadministered drugs in children.
Topics: Amiodarone; Child, Preschool; Digoxin; Drug Interactions; Drug Therapy, Combination; Humans; Infant; Infant, Newborn; Nifedipine; Quinidine; Spironolactone; Verapamil | 1985 |
[Verapamil-induced digoxin poisoning in uremia].
Topics: Digoxin; Drug Interactions; Female; Humans; Middle Aged; Renal Dialysis; Uremia; Verapamil | 1985 |
Influence of verapamil on the digoxin-induced inotropic effect in guinea-pig isolated atria.
Topics: Animals; Atrial Function; Cardiac Glycosides; Digoxin; Electric Stimulation; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Myocardial Contraction; Reserpine; Verapamil | 1985 |
Digoxin intoxication induced by verapamil in an uremic patient.
Topics: Digoxin; Drug Interactions; Female; Humans; Kinetics; Middle Aged; Renal Dialysis; Uremia; Verapamil | 1985 |
[State of blood digoxin after acute simultaneous administration of digoxin and verapamil].
Topics: Atrial Fibrillation; Digoxin; Drug Therapy, Combination; Humans; Radioimmunoassay; Verapamil | 1985 |
Atrial arrhythmias exacerbated by theophylline. Response to verapamil and evidence for triggered activity in man.
Topics: Aged; Digoxin; Electrocardiography; Female; Heart Atria; Humans; Lung Diseases, Obstructive; Recurrence; Tachycardia; Theophylline; Verapamil | 1985 |
[Diagnosis and treatment of fetal tachycardia. Apropos of 2 cases].
Topics: Digoxin; Echocardiography; Female; Humans; Pregnancy; Prenatal Diagnosis; Tachycardia; Verapamil | 1985 |
[Ventricular fibrillation as a result of digoxin and verapamil interaction].
Topics: Atrial Fibrillation; Digoxin; Drug Synergism; Drug Therapy, Combination; Female; Humans; Middle Aged; Ventricular Fibrillation; Verapamil | 1985 |
[Interaction with digoxin].
Topics: Digoxin; Drug Interactions; Humans; Quinidine; Verapamil | 1985 |
[Comparative studies on the effects of oxyfedrine, epinephrine and digitalis glycosides on the function and high-energy phosphates of the guinea-pig heart].
Topics: Amino Alcohols; Animals; Blood Pressure; Cardiac Output; Cardiac Volume; Digitalis Glycosides; Digoxin; Dose-Response Relationship, Drug; Drug Combinations; Epinephrine; Guinea Pigs; Heart; Heart Rate; Isoproterenol; Myocardium; Phenethylamines; Phosphates; Propiophenones; Pulmonary Circulation; Venous Pressure; Verapamil | 1974 |
Verapamil induced premature ventricular beats before reversion of supraventricular tachycardia.
Topics: Adolescent; Adult; Aged; Arrhythmias, Cardiac; Blood Pressure; Bradycardia; Digoxin; Electrocardiography; Female; Heart Ventricles; Humans; Injections, Intravenous; Male; Methyldopa; Middle Aged; Syndrome; Tachycardia; Tachycardia, Paroxysmal; Verapamil; Wolff-Parkinson-White Syndrome | 1974 |
[Gradulon and gradulon s. T. in the treatment of heart diseases of various causes in the daily practice].
Topics: Arrhythmias, Cardiac; Benzoates; Coronary Disease; Digoxin; Drug Combinations; Heart Diseases; Heart Failure; Humans; Morpholines; Tranquilizing Agents; Verapamil | 1972 |
Congenital arrhythmias with supraventricular tachycardia in the perinatal period.
Topics: Ajmaline; Apgar Score; Arrhythmias, Cardiac; Cesarean Section; Digoxin; Electrocardiography; Extraction, Obstetrical; Female; Fetus; Heart Block; Humans; Infant; Infant, Newborn; Lanatosides; Pregnancy; Prenatal Diagnosis; Tachycardia; Tachycardia, Paroxysmal; Ventricular Fibrillation; Verapamil; Wolff-Parkinson-White Syndrome | 1973 |
Present status and treatment of paroxysmal supraventricular tachycardia.
Topics: Child; Child, Preschool; Digoxin; Electric Countershock; Electrocardiography; Humans; Infant; Lidocaine; Pacemaker, Artificial; Posture; Procainamide; Propranolol; Tachycardia, Paroxysmal; Valsalva Maneuver; Verapamil | 1972 |
[Disturbances of cardiac rhythm and their treatment].
Topics: Adult; Aged; Ajmaline; Arrhythmias, Cardiac; Digitoxin; Digoxin; Humans; Lidocaine; Metaproterenol; Middle Aged; Phenytoin; Procainamide; Quinidine; Reserpine; Verapamil | 1970 |
Effect of procainamide on myocardial contractile function and digoxin inotropy.
Topics: Animals; Calcium; Cats; Digoxin; Drug Interactions; Ion Channels; Myocardial Contraction; Papillary Muscles; Procainamide; Propranolol; Receptors, Adrenergic, beta; Stimulation, Chemical; Verapamil | 1984 |
Drugs and the heart. IV. Antiarrhythmic agents.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Bretylium Compounds; Digoxin; Disopyramide; Heart Conduction System; Hemodynamics; Humans; Lidocaine; Mexiletine; Procainamide; Quinidine; Verapamil | 1980 |
Arrhythmias: common dilemmas in treatment.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Carotid Sinus; Digoxin; Electric Countershock; Heart Rate; Humans; Massage; Tachycardia; Verapamil | 1981 |
[Therapy of cardiomyopathies].
Topics: Adrenergic beta-Agonists; Anti-Arrhythmia Agents; Anticoagulants; Captopril; Cardiac Glycosides; Cardiomyopathies; Diet, Sodium-Restricted; Digitoxin; Digoxin; Dihydralazine; Diuretics; Humans; Nitrates; Practolol; Prenalterol; Temperance; Vasodilator Agents; Verapamil | 1982 |
Management of cardiac drug overdose.
Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Disopyramide; Humans; Phenytoin; Poison Control Centers; Verapamil | 1984 |
Sustained "slow-fast" and "fast-slow" AV nodal re-entrant tachycardia in a patient with recurrent supraventricular tachycardia.
Topics: Adult; Atrioventricular Node; Bundle of His; Cardiac Pacing, Artificial; Digoxin; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Block; Heart Conduction System; Humans; Tachycardia, Paroxysmal; Verapamil | 1983 |
Atrial fibrillation.
Topics: Age Factors; Aged; Atrial Fibrillation; Cardiomegaly; Digoxin; Electric Countershock; Electrocardiography; Heart Failure; Humans; Hypertension; Male; Middle Aged; Mitral Valve Stenosis; Myocardial Infarction; Verapamil | 1982 |
Verapamil-digoxin interaction.
Topics: Aged; Coronary Disease; Digoxin; Drug Interactions; Drug Therapy, Combination; Female; Heart Arrest; Humans; Male; Ventricular Fibrillation; Verapamil | 1984 |
Cardiogenic pulmonary edema.
Topics: Aminophylline; Cardiovascular Agents; Digoxin; Diuretics; Dobutamine; Dopamine; Heart Failure; Humans; Morphine; Nitroglycerin; Nitroprusside; Pulmonary Edema; Verapamil | 1984 |
Verapamil preserves myocardial contractility in the hereditary cardiomyopathy of the Syrian hamster.
Topics: Actins; Adenosine Triphosphatases; Animals; Cardiomyopathies; Cricetinae; Digoxin; Hydralazine; Mesocricetus; Myocardial Contraction; Myocardium; Myosins; Papillary Muscles; Sodium Chloride; Verapamil | 1982 |
Characteristics of the digoxin-quinidine and digoxin-verapamil interactions in the rat kidney.
Topics: Animals; Binding, Competitive; Digoxin; Drug Interactions; Iodine Radioisotopes; Kidney; Kinetics; Male; Protein Binding; Quinidine; Rats; Rats, Inbred Strains; Verapamil | 1984 |
Interaction between digoxin and verapamil in isolated cardiac muscle.
Topics: Animals; Digoxin; Drug Interactions; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Papillary Muscles; Verapamil | 1984 |
Treatment of intrauterine supraventricular tachycardia with digoxin and verapamil.
Topics: Adult; Digoxin; Drug Therapy, Combination; Electrocardiography; Female; Fetal Diseases; Humans; Pregnancy; Tachycardia; Verapamil | 1984 |
Pulmonary vascular response to digoxin in newborn lambs.
Topics: Animals; Animals, Newborn; Digoxin; Hemodynamics; Hypoxia; Oxygen Consumption; Pulmonary Circulation; Sheep; Vascular Resistance; Verapamil | 1984 |
The influence of calcium antagonists on plasma digoxin concentration.
Topics: Digoxin; Humans; Kinetics; Lymphocytes; Receptors, Drug; Sodium; Sodium-Potassium-Exchanging ATPase; Stroke Volume; Systole; Verapamil | 1984 |
Influence of verapamil on the inotropism and pharmacokinetics of digoxin.
Topics: Adult; Blood Pressure; Digoxin; Drug Interactions; Half-Life; Heart Rate; Humans; Kinetics; Male; Myocardial Contraction; Verapamil | 1983 |
[Fetal hydrops as a result of supraventricular tachycardia].
Topics: Adult; Cesarean Section; Digoxin; Edema; Female; Fetal Diseases; Humans; Infant, Newborn; Male; Pregnancy; Tachycardia, Paroxysmal; Verapamil | 1983 |
Sonographic evaluation of prenatal therapy for fetal supraventricular tachycardia and congestive heart failure. A case report.
Topics: Adult; Animals; Digoxin; Dogs; Female; Fetal Diseases; Heart Failure; Humans; Infant, Newborn; Pregnancy; Prenatal Diagnosis; Propranolol; Tachycardia; Ultrasonography; Verapamil | 1983 |
[Increased digitalis-like activity in combined administration of calcium antagonists and digitalis preparations].
Topics: Aged; Digoxin; Drug Interactions; Drug Therapy, Combination; Heart Failure; Humans; Medigoxin; Middle Aged; Nifedipine; Verapamil | 1983 |
Interaction of digoxin with verapamil, indomethacin, and other coadministered drugs: a comparative study in rat tissue.
Topics: Animals; Creatinine; Digoxin; Indomethacin; Male; Quinidine; Rats; Rats, Inbred Strains; Verapamil | 1983 |
Verapamil and digoxin: interactions in the rat.
Topics: Animals; Arrhythmias, Cardiac; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Kinetics; Male; Rats; Rats, Inbred Strains; Time Factors; Tissue Distribution; Verapamil | 1983 |
Interaction between verapamil and beta-methyldigoxin. Study by 86Rubidium uptake in erythrocytes.
Topics: Aged; Digoxin; Drug Interactions; Erythrocytes; Humans; Medigoxin; Middle Aged; Radioisotopes; Rubidium; Time Factors; Verapamil | 1983 |
[Interactions between digoxin and amiodarone (Cordarone), verapamil (Isoptin) and melsidomine (Corvatone)].
Topics: Adult; Amiodarone; Cardiotonic Agents; Coronary Disease; Digoxin; Drug Interactions; Humans; Male; Middle Aged; Molsidomine; Sydnones; Verapamil | 1983 |
Long-term oral treatment with high doses of verapamil in lone atrial fibrillation.
Topics: Administration, Oral; Adult; Atrial Fibrillation; Digoxin; Drug Interactions; Heart Rate; Humans; Male; Middle Aged; Verapamil | 1984 |
[Method of evaluating antiarrhythmic therapy in patients with paroxysms of supraventricular tachycardia].
Topics: Adolescent; Adult; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Digoxin; Drug Evaluation; Electric Stimulation; Female; Humans; Male; Middle Aged; Procainamide; Propranolol; Quinidine; Tachycardia, Paroxysmal; Verapamil | 1984 |
[Effect of verapamil on plasma levels of digoxin in man].
Topics: Adult; Digoxin; Drug Interactions; Humans; Immunoenzyme Techniques; Middle Aged; Verapamil | 1982 |
Digoxin-verapamil interaction--is it mutual?
Topics: Digoxin; Drug Interactions; Humans; Verapamil | 1983 |
Pre-excitation syndrome in infants and children. Effect of digoxin, verapamil, and amiodarone.
Topics: Adolescent; Amiodarone; Child; Child, Preschool; Digoxin; Electrocardiography; Humans; Infant; Infant, Newborn; Tachycardia, Paroxysmal; Verapamil; Wolff-Parkinson-White Syndrome | 1983 |
Verapamil, propranolol, and hydralazine protect against the acute cardiac depression induced by adriamycin.
Topics: Animals; Depression, Chemical; Digoxin; Doxorubicin; Heart; Hemodynamics; Hydralazine; In Vitro Techniques; Myocardial Contraction; Perfusion; Propranolol; Rats; Rats, Inbred Strains; Verapamil | 1983 |
Impotence during therapy with verapamil.
Topics: Adult; Aged; Digoxin; Drug Therapy, Combination; Erectile Dysfunction; Heart Diseases; Humans; Male; Middle Aged; Verapamil | 1983 |
Verapamil-induced changes in digoxin kinetics and intraerythrocytic sodium concentration.
Topics: Adult; Digoxin; Drug Interactions; Erythrocytes; Humans; Kinetics; Male; Metabolic Clearance Rate; Ouabain; Sodium; Verapamil | 1983 |
Verapamil in atrial fibrillation: The expected, the unexpected, and the unknown.
Topics: Atrial Fibrillation; Digoxin; Drug Interactions; Heart Ventricles; Humans; Kinetics; Verapamil; Wolff-Parkinson-White Syndrome | 1983 |
[Influence of verapamil on the plasma level of digoxin in man].
Topics: Adult; Digoxin; Drug Interactions; Heart Diseases; Humans; Middle Aged; Verapamil | 1982 |
Asystole after verapamil and digoxin.
Topics: Arrhythmia, Sinus; Arrhythmias, Cardiac; Digoxin; Drug Synergism; Female; Heart Arrest; Humans; Middle Aged; Verapamil | 1980 |
The influence of verapamil on serum digoxin concentration.
Topics: Adult; Aged; Atrial Fibrillation; Chronic Disease; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Kidney; Kinetics; Male; Middle Aged; Verapamil | 1982 |
Acute and chronic pharmacodynamic interaction of verapamil and digoxin in atrial fibrillation.
Topics: Administration, Oral; Atrial Fibrillation; Blood Pressure; Chronic Disease; Digoxin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Electrocardiography; Female; Heart Rate; Humans; Infusions, Parenteral; Male; Middle Aged; Physical Exertion; Verapamil | 1982 |
Anti-arrhythmic agents in ischemic heart disease: supraventricular arrhythmias, digitalis toxicity and chronic stable ventricular ectopic beats.
Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Digitalis; Digoxin; Heart Ventricles; Humans; Plants, Medicinal; Plants, Toxic; Potassium; Quinidine; Verapamil | 1982 |
The long-term effect of verapamil on plasma digoxin concentration and renal digoxin clearance in healthy subjects.
Topics: Adult; Digoxin; Drug Interactions; Female; Humans; Kidney; Kinetics; Male; Middle Aged; Time Factors; Verapamil | 1982 |
[Mobile coronary unit of Florence: early care of arrhythmias not due to acute coronary insufficiency].
Topics: Adult; Aged; Ajmaline; Ambulances; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bunaftine; Coronary Care Units; Digoxin; Female; Humans; Italy; Male; Middle Aged; Verapamil | 1982 |
Digoxin-verapamil interaction.
Topics: Adult; Body Weight; Digoxin; Drug Interactions; Female; Half-Life; Humans; Kidney; Kinetics; Male; Middle Aged; Verapamil | 1981 |
Complete abolition of the reentrant supraventricular tachycardia zone using a new modality of cardiac pacing with simultaneous atrioventricular stimulation.
Topics: Adult; Atrioventricular Node; Cardiac Pacing, Artificial; Digoxin; Electrodes; Electrophysiology; Female; Follow-Up Studies; Heart Conduction System; Heart Ventricles; Humans; Male; Middle Aged; Propranolol; Quinidine; Tachycardia; Time Factors; Verapamil | 1980 |
Verapamil-digoxin interaction.
Topics: Digoxin; Drug Interactions; Humans; Verapamil | 1980 |
Ionic basis of digitalis toxicity in mammalian ventricle: demonstration of transient inward current.
Topics: Animals; Calcium; Digitalis Glycosides; Digoxin; Electrophysiology; Ferrets; Guinea Pigs; Heart; In Vitro Techniques; Membrane Potentials; Ouabain; Papillary Muscles; Verapamil | 1980 |
A basis for the pharmacology of hearing.
Topics: Acetylcholine; Action Potentials; Animals; Atropine; Brain; Calcium; Cochlea; Digoxin; Efferent Pathways; Guinea Pigs; Hearing; Humans; Physostigmine; Verapamil | 1980 |
[A case of arrhythmogenic effects of quinidine, digoxin and finoptin combination].
Topics: Adult; Arrhythmias, Cardiac; Digoxin; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Quinidine; Verapamil | 1995 |
Digoxin-induced ventricular arrhythmias in the guinea pig heart in vivo: evidence for a role of endogenous catecholamines in the genesis of delayed afterdepolarizations and triggered activity.
Topics: Adenosine; Analysis of Variance; Animals; Arrhythmias, Cardiac; Catecholamines; Digoxin; Disease Models, Animal; Electrocardiography; Female; Guinea Pigs; Male; Propranolol; Random Allocation; Reserpine; Ventricular Dysfunction; Verapamil | 1995 |
Effect of exercise on cycle length in atrial flutter.
Topics: Adult; Atrial Flutter; Digoxin; Electrocardiography; Exercise; Female; Humans; Male; Verapamil | 1995 |
Comparison of the frequency-dependent effects on the atrioventricular node of verapamil, amiodarone, digoxin, and diltiazem in isolated guinea pig hearts.
Topics: Amiodarone; Animals; Atrioventricular Node; Cardiac Pacing, Artificial; Computer Simulation; Digoxin; Diltiazem; Electric Stimulation; Electrocardiography; Female; Guinea Pigs; Heart; Heart Rate; In Vitro Techniques; Male; Verapamil | 1995 |
The verdant octogenarian.
Topics: Aged; Aged, 80 and over; Bipolar Disorder; Digoxin; Drug Therapy, Combination; Female; Humans; Metabolic Clearance Rate; Pulmonary Heart Disease; Verapamil | 1994 |
[Adenosine triphosphate for supraventricular tachycardia in newborns and suckling infants].
Topics: Adenosine Triphosphate; Digoxin; Drug Therapy, Combination; Echocardiography; Electrocardiography; Electrocardiography, Ambulatory; Female; Humans; Infant, Newborn; Propafenone; Tachycardia, Supraventricular; Verapamil; Wolff-Parkinson-White Syndrome | 1994 |
A pregnant lady with narrow complex tachycardia.
Topics: Adult; Diagnosis, Differential; Digoxin; Drug Therapy, Combination; Electrocardiography; Female; Humans; Pregnancy; Pregnancy Complications, Cardiovascular; Propranolol; Tachycardia, Ectopic Atrial; Verapamil | 1994 |
P-glycoprotein-mediated renal tubular secretion of digoxin: the toxicological significance of the urine-blood barrier model.
Topics: Analysis of Variance; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Carrier Proteins; Cell Line; Digoxin; Kidney Tubules; Membrane Glycoproteins; Models, Biological; Swine; Verapamil | 1993 |
Role of P-glycoprotein in renal tubular secretion of digoxin in the isolated perfused rat kidney.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Carrier Proteins; Digoxin; In Vitro Techniques; Inulin; Kidney; Kidney Tubules; Male; Membrane Glycoproteins; Perfusion; Quinidine; Rats; Rats, Wistar; Tritium; Verapamil | 1993 |
The mechanism of the verapamil-digoxin interaction in renal tubular cells (LLC-PK1).
Topics: Animals; Biological Transport; Cells, Cultured; Digoxin; Drug Interactions; Kidney Tubules; Stereoisomerism; Swine; Verapamil | 1993 |
[The transplacental therapy of fetal tachyarrhythmias].
Topics: Digoxin; Drug Therapy, Combination; Echocardiography; Female; Fetal Diseases; Gestational Age; Humans; Placenta; Pregnancy; Remission Induction; Tachycardia; Ultrasonography, Prenatal; Verapamil | 1993 |
Efficacy and risks of medical therapy for supraventricular tachycardia in neonates and infants.
Topics: Anti-Arrhythmia Agents; Catheter Ablation; Digoxin; Electrocardiography; Esophagus; Female; Follow-Up Studies; Heart Block; Heart Conduction System; Heart Defects, Congenital; Humans; Infant; Infant, Newborn; Male; Propranolol; Recurrence; Retrospective Studies; Risk Factors; Survival Rate; Tachycardia, Atrioventricular Nodal Reentry; Tachycardia, Ectopic Atrial; Tachycardia, Supraventricular; Verapamil | 1996 |
New treatment of atrial fibrillation.
Topics: Adrenergic beta-Antagonists; Atrial Fibrillation; Calcium Channel Blockers; Digoxin; Diltiazem; Drug Therapy, Combination; Emergency Medicine; Heart Failure; Humans; Propanolamines; Verapamil | 1996 |
How to measure AV nodal refractoriness in the presence of verapamil, amiodarone, digoxin, and diltiazem.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Cardiac Pacing, Artificial; Digoxin; Diltiazem; Electrocardiography; Female; Fourier Analysis; Guinea Pigs; Heart Rate; Male; Signal Processing, Computer-Assisted; Verapamil | 1996 |
Quantification of rate-dependent effects of verapamil, diltiazem, and digoxin on atrioventricular conduction.
Topics: Adaptation, Physiological; Animals; Atrioventricular Node; Calcium Channel Blockers; Digoxin; Diltiazem; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Male; Sinoatrial Node; Time Factors; Verapamil | 1996 |
Effects of pinacidil, verapamil, and heart rate on afterdepolarizations in the guinea-pig heart in vivo.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Action Potentials; Animals; Calcium Channel Blockers; Cesium; Chlorides; Digoxin; Female; Guanidines; Guinea Pigs; Heart; Heart Rate; Male; Pinacidil; Stereoisomerism; Verapamil | 1996 |
The stereoisomers quinine and quinidine exhibit a marked stereoselectivity in the inhibition of hepatobiliary transport of cardiac glycosides.
Topics: Animals; Biliary Tract; Biological Transport; Calcium Channel Blockers; Cardiac Glycosides; Cardiotonic Agents; Digoxin; Drug Interactions; Liver; Male; Metabolic Clearance Rate; Ouabain; Quinidine; Quinine; Rats; Rats, Wistar; Stereoisomerism; Verapamil | 1998 |
Stereoselective inhibition by the diastereomers quinidine and quinine of uptake of cardiac glycosides into isolated rat hepatocytes.
Topics: Animals; Calcium Channel Blockers; Cardiotonic Agents; Digoxin; In Vitro Techniques; Male; Ouabain; Quinidine; Quinine; Rats; Rats, Wistar; Stereoisomerism; Verapamil | 1998 |
A model for the prediction of digoxin-drug interactions at the renal tubular cell level.
Topics: Animals; Anti-Arrhythmia Agents; Antifungal Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Calcium Channel Blockers; Cells, Cultured; Digoxin; Diuretics; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Female; Hormone Antagonists; Immunosuppressive Agents; Kidney Tubules; Male; Models, Biological; Propafenone; Swine; Verapamil | 1998 |
Influence of verapamil and digoxin on the in vitro binding of doxorubicin to the rat heart.
Topics: Animals; Antibiotics, Antineoplastic; Digoxin; Doxorubicin; Myocardium; Rats; Rats, Wistar; Verapamil | 1998 |
Rate control therapy for atrial fibrillation following coronary artery bypass surgery.
Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Digoxin; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Male; Patient Selection; Postoperative Complications; Time Factors; Verapamil | 1998 |
Fetal tachycardias: management and outcome of 127 consecutive cases.
Topics: Adenosine; Amiodarone; Anti-Arrhythmia Agents; Chi-Square Distribution; Digoxin; Female; Fetal Distress; Fetus; Flecainide; Humans; Hydrops Fetalis; Maternal-Fetal Exchange; Pregnancy; Retrospective Studies; Statistics, Nonparametric; Verapamil | 1998 |
Adenosine in the diagnosis of wide complex tachycardias.
Topics: Adenosine; Aged; Atrial Fibrillation; Coronary Disease; Diagnosis, Differential; Digoxin; Electrocardiography; Humans; Male; Postoperative Complications; Tachycardia; Verapamil | 1994 |
Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers.
Topics: Anti-Anxiety Agents; Antifungal Agents; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Calcium Channel Blockers; Catalytic Domain; Cell Polarity; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Digoxin; Enzyme Inhibitors; Epithelial Cells; Gene Expression; Histamine H1 Antagonists; Humans; Hydroxylation; Intestinal Mucosa; Intestines; Ketoconazole; Kinetics; Oligonucleotide Probes; Oxidoreductases, N-Demethylating; Piperidines; RNA, Messenger; Terfenadine; Tritium; Verapamil | 1999 |
Characterization of the major metabolites of verapamil as substrates and inhibitors of P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Caco-2 Cells; Calcium Channel Blockers; Cardiotonic Agents; Cell Line; Digoxin; Epithelial Cells; Humans; Kinetics; LLC-PK1 Cells; Nitriles; Swine; Verapamil | 2000 |
Inhibitors of Na-K-ATPase in human urine: effects of ouabain-like factors and of vanadium-diascorbate on calcium mobilization in rat vascular smooth muscle cells: comparison with the effects of ouabain, angiotensin II, and arginine-vasopressin.
Topics: Adult; Angiotensin II; Animals; Aorta, Thoracic; Arginine Vasopressin; Ascorbic Acid; Biological Factors; Biological Transport; Calcium; Calcium Channel Blockers; Cardenolides; Cells, Cultured; Digoxin; Enzyme Inhibitors; Gallic Acid; Humans; Hypertension, Renal; Male; Muscle, Smooth, Vascular; Nickel; Organometallic Compounds; Ouabain; Rats; Saponins; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents; Verapamil | 2000 |
MDR3 P-glycoprotein, a phosphatidylcholine translocase, transports several cytotoxic drugs and directly interacts with drugs as judged by interference with nucleotide trapping.
Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Biological Transport; Cell Polarity; Cells, Cultured; Cyclosporine; Cyclosporins; Cytotoxins; Daunorubicin; Digoxin; Epithelial Cells; Humans; Ivermectin; Kidney; Paclitaxel; Pharmaceutical Preparations; Phosphatidylcholines; Recombinant Proteins; Spodoptera; Swine; Verapamil; Vinblastine | 2000 |
Calcium and digoxin vs. calcium alone for severe verapamil toxicity.
Topics: Animals; Calcium; Calcium Channel Blockers; Chi-Square Distribution; Digoxin; Disease Models, Animal; Dogs; Drug Overdose; Drug Therapy, Combination; Male; Reference Values; Survival Rate; Treatment Outcome; Verapamil | 2000 |
[Treatment of cardiac arrhythmia in pregnant women].
Topics: Adrenergic beta-Antagonists; Alcohol Drinking; Arrhythmias, Cardiac; Digoxin; Electric Countershock; Female; Heart Valve Diseases; Humans; Lidocaine; Mitral Valve Prolapse; Pregnancy; Pregnancy Complications, Cardiovascular; Procainamide; Quinidine; Secondary Prevention; Smoking; Smoking Prevention; Verapamil | 2000 |
Rhabdomyolysis and acute renal failure in a cardiac transplant recipient due to multiple drug interactions.
Topics: Acute Kidney Injury; Anti-Arrhythmia Agents; Cyclosporine; Digoxin; Drug Interactions; Enzyme Inhibitors; Heart Transplantation; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Male; Middle Aged; Rhabdomyolysis; Simvastatin; Verapamil | 2000 |
Kinetic profiling of P-glycoprotein-mediated drug efflux in rat and human intestinal epithelia.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Calcium Channel Blockers; Cardiotonic Agents; Colonic Neoplasms; Digoxin; DNA Primers; Epithelium; Glycoproteins; Humans; Intestinal Mucosa; Kinetics; Male; Pharmaceutical Preparations; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Verapamil; Vinblastine | 2001 |
Profibrillatory effects of verapamil but not of digoxin in the goat model of atrial fibrillation.
Topics: Acute Disease; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Chronic Disease; Digoxin; Disease Models, Animal; Electrocardiography; Electrodes, Implanted; Electrophysiologic Techniques, Cardiac; Goats; Heart Atria; Heart Conduction System; Heart Rate; Injections, Intravenous; Verapamil | 2000 |
Uptake and efflux of the peptidic delta-opioid receptor agonist.
Topics: Analgesics, Opioid; Animals; Anion Transport Proteins; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Calcium Channel Blockers; Carrier Proteins; Digoxin; Enkephalin, D-Penicillamine (2,5)-; Enzyme Inhibitors; Estradiol; Histamine H1 Antagonists; Male; Mice; Mice, Knockout; Perfusion; Receptors, Opioid, delta; Terfenadine; Verapamil | 2001 |
The role of P-glycoprotein in limiting intestinal regional absorption of digoxin in rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Digoxin; Gastrointestinal Motility; Hemodynamics; Intestinal Absorption; Male; Perfusion; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Verapamil | 2001 |
The anthelminthic agent albendazole does not interact with p-glycoprotein.
Topics: Albendazole; Animals; Anthelmintics; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Caco-2 Cells; Calcium Channel Blockers; Cell Line; Chromatography, High Pressure Liquid; Digoxin; Enzyme Inhibitors; Humans; LLC-PK1 Cells; Male; Mice; Mice, Knockout; Quinidine; Swine; Tissue Distribution; Verapamil | 2002 |
Pharmacoepidemiologic detection of calcium channel blocker-induced change on digoxin clearance using multiple trough screen analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Calcium Channel Blockers; Creatinine; Digoxin; Diltiazem; Drug Interactions; Female; Heart Failure; Humans; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Models, Statistical; Nifedipine; Pharmacoepidemiology; Regression Analysis; Reproducibility of Results; Spironolactone; Verapamil | 2002 |
Effects of 12 Ca2+ antagonists on multidrug resistance, MDR1-mediated transport and MDR1 mRNA expression.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Digoxin; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Gene Expression; Humans; Nifedipine; Paclitaxel; RNA, Messenger; Swine; Tritium; Tumor Cells, Cultured; Verapamil; Vinblastine | 2002 |
Epidemiology of atrial fibrillation.
Topics: Atrial Fibrillation; Digoxin; Humans; United Kingdom; Verapamil | 2002 |
[Influence of ion pump-inhibiting drugs on the accumulation of ofloxacin and grepafloxacin in human polymorphonuclear leukocytes].
Topics: Anti-Infective Agents; Calcium Channel Blockers; Digoxin; Enzyme Inhibitors; Fluoroquinolones; Humans; Ion Pumps; Neutrophils; Ofloxacin; Omeprazole; Piperazines; Verapamil | 2002 |
An in vitro examination of the impact of polyethylene glycol 400, Pluronic P85, and vitamin E d-alpha-tocopheryl polyethylene glycol 1000 succinate on P-glycoprotein efflux and enterocyte-based metabolism in excised rat intestine.
Topics: Adenosine Triphosphate; Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cytochrome P-450 CYP3A; Digoxin; Enterocytes; In Vitro Techniques; Intestines; Male; Oxidoreductases, N-Demethylating; Poloxamer; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Solvents; Succinates; Verapamil; Vitamin E | 2002 |
Effects of carvedilol on MDR1-mediated multidrug resistance: comparison with verapamil.
Topics: Adrenergic beta-Antagonists; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Carbazoles; Carvedilol; Cell Division; Cell Line; Daunorubicin; Digoxin; DNA, Complementary; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Epithelial Cells; Fluorouracil; HeLa Cells; Humans; Inhibitory Concentration 50; Kidney; Paclitaxel; Propanolamines; Swine; Transfection; Verapamil; Vinblastine | 2003 |
An autopsy case of combined drug intoxication involving verapamil, metoprolol and digoxin.
Topics: Adrenergic beta-Antagonists; Adult; Anti-Arrhythmia Agents; Calcium Channel Blockers; Digoxin; Drug Interactions; Drug Overdose; Humans; Male; Metoprolol; Suicide; Verapamil | 2003 |
Drug interactions.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Cytochrome P-450 Enzyme System; Digoxin; Drug Interactions; Drug Therapy, Combination; Enzyme Induction; Humans; Isoenzymes; Piperazines; Purines; Quinidine; Sildenafil Citrate; Sulfones; Vasodilator Agents; Ventricular Premature Complexes; Verapamil | 2003 |
Role of P-glycoprotein in pharmacokinetics and drug interactions of digoxin and beta-methyldigoxin in rats.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cyclosporine; Digoxin; Drug Interactions; In Vitro Techniques; Intestinal Absorption; Male; Medigoxin; Rats; Rats, Wistar; Verapamil | 2003 |
Lack of interaction of digoxin and P-glycoprotein inhibitors, quinidine and verapamil in human placenta in vitro.
Topics: Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Digoxin; Drug Interactions; Enzyme Inhibitors; Female; Humans; Maternal-Fetal Exchange; Organ Culture Techniques; Placenta; Pregnancy; Quinidine; Verapamil | 2003 |
Verapamil metabolites: potential P-glycoprotein-mediated multidrug resistance reversal agents.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Digoxin; Dogs; Drug Resistance, Neoplasm; Verapamil; Vinblastine | 2003 |
Management of patients with persistent chest pain and ST-segment elevation during 5-fluorouracil treatment: report about two cases.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antimetabolites, Antineoplastic; Atrial Fibrillation; Captopril; Chest Pain; Colorectal Neoplasms; Coronary Angiography; Digoxin; Disease Management; Echocardiography; Electrocardiography; Fluorouracil; Humans; Laryngeal Neoplasms; Middle Aged; Myocardial Infarction; Nitrates; Verapamil | 2003 |
Dose-dependent hemodynamic effect of digoxin therapy in severe verapamil toxicity.
Topics: Animals; Antidotes; Blood Pressure; Calcium Channel Blockers; Calcium Chloride; Digoxin; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hemodynamics; Male; Reference Values; Treatment Outcome; Verapamil | 2004 |
[Correction of rate and structure of ventricular rhythm in permanent atrial fibrillation: a novel pathogenetic approach].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Digoxin; Electrocardiography; Female; Heart Rate; Humans; Male; Middle Aged; Periodicity; Sotalol; Ventricular Premature Complexes; Verapamil | 2004 |
Assessment of drug interactions in hepatobiliary transport using rhodamine 123 in sandwich-cultured rat hepatocytes.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cell Culture Techniques; Cells, Cultured; Collagenases; Digoxin; Drug Interactions; Hepatocytes; Male; Progesterone; Quercetin; Quinidine; Rats; Rats, Wistar; Rhodamine 123; Verapamil | 2005 |
[Diagnosis and treatment of haemodynamically significant fetal tachycardia--in 33 cases].
Topics: Amiodarone; Anti-Arrhythmia Agents; Digoxin; Electric Countershock; Female; Fetal Diseases; Follow-Up Studies; Gestational Age; Hemodynamics; Humans; Male; Retrospective Studies; Tachycardia; Tachycardia, Supraventricular; Verapamil | 2004 |
Inhibition of P-glycoprotein-mediated transport by extracts of and monoterpenoids contained in Zanthoxyli fructus.
Topics: Acyclic Monoterpenes; Aldehydes; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporins; Digoxin; Drug Interactions; Humans; Inhibitory Concentration 50; LLC-PK1 Cells; Monoterpenes; Plant Extracts; Swine; Transfection; Verapamil; Zanthoxylum | 2005 |
The effects of sinomenine on intestinal absorption of paeoniflorin by the everted rat gut sac model.
Topics: Animals; Anti-Inflammatory Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzoates; Bridged-Ring Compounds; Digoxin; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Glucosides; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Models, Animal; Monoterpenes; Morphinans; Paeonia; Quinidine; Rats; Rats, Sprague-Dawley; Sinomenium; Time Factors; Verapamil | 2006 |
Limited interaction between tacrolimus and P-glycoprotein in the rat small intestine.
Topics: Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Calcium Channel Blockers; Cardiotonic Agents; Cyclosporine; Digoxin; Immunosuppressive Agents; Intestinal Absorption; Intestine, Small; Jejunum; Methylprednisolone; Progesterone; Rats; Tacrolimus; Verapamil; Vinblastine | 2006 |
Inadvertent toxic drug reaction in the management of atrial fibrillation.
Topics: Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Digoxin; Drug Interactions; Electrocardiography; Female; Humans; Hypotension; Middle Aged; Sotalol; Time Factors; Verapamil | 2006 |
Establishment and characterization of the transformants stably-expressing MDR1 derived from various animal species in LLC-PK1.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Sub-Family B Member 4; ATP-Binding Cassette Transporters; Biological Transport; Clarithromycin; Digoxin; Dogs; Dose-Response Relationship, Drug; Haplorhini; Humans; Kinetics; LLC-PK1 Cells; Mice; Pharmaceutical Preparations; Rats; RNA, Messenger; Swine; Transfection; Verapamil; Vinblastine | 2006 |
The complexity of intestinal absorption and exsorption of digoxin in rats.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Digoxin; Ileum; In Vitro Techniques; Intestinal Absorption; Jejunum; Male; Microvilli; Organic Anion Transporters; Propionates; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Sulfobromophthalein; Tetrahydroisoquinolines; Verapamil | 2006 |
Impact of cremophor-EL and polysorbate-80 on digoxin permeability across rat jejunum: delineation of thermodynamic and transporter related events using the reciprocal permeability approach.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Digoxin; Glycerol; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Jejunum; Male; Permeability; Polysorbates; Rats; Rats, Sprague-Dawley; Serous Membrane; Surface-Active Agents; Thermodynamics; Vanadates; Verapamil | 2007 |
Induction of human P-glycoprotein in Caco-2 cells: development of a highly sensitive assay system for P-glycoprotein-mediated drug transport.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blotting, Western; Caco-2 Cells; Cell Differentiation; Cell Growth Processes; Cell Line; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Digoxin; Gene Expression; Humans; Membrane Transport Proteins; Microfilament Proteins; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Peptide Transporter 1; Pharmaceutical Preparations; Quinidine; RNA, Messenger; Symporters; Verapamil; Vinblastine | 2006 |
Species differences of inhibitory effects on P-glycoprotein-mediated drug transport.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cyclosporine; Daunorubicin; Digoxin; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Quinidine; Rats; Species Specificity; Verapamil | 2007 |
Anthranoid laxatives influence the absorption of poorly permeable drugs in human intestinal cell culture model (Caco-2).
Topics: Absorption; Acetaminophen; Anthraquinones; Beverages; Caco-2 Cells; Carbon Radioisotopes; Cathartics; Cell Membrane Permeability; Digoxin; Furosemide; Humans; Ketoprofen; Mannitol; Plant Leaves; Propranolol; Senna Extract; Sennosides; Verapamil | 2007 |
In-vitro transport characteristics discriminate wild-type ABCB1 (MDR1) from ALA893SER and ALA893THR polymorphisms.
Topics: Alleles; Amino Acid Substitution; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Cell Line; Cloning, Molecular; Digoxin; Enzyme Inhibitors; Humans; In Vitro Techniques; Intestinal Mucosa; Kinetics; Organic Anion Transporters; Pharmacogenetics; Polymorphism, Single Nucleotide; Rats; Recombinant Proteins; Spodoptera; Verapamil; Vincristine | 2006 |
Role of P-glycoprotein in the intestinal absorption of glabridin, an active flavonoid from the root of Glycyrrhiza glabra.
Topics: Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Availability; Biological Transport, Active; Caco-2 Cells; Cell Membrane Permeability; Digoxin; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Flavonoids; Glucuronides; Glycyrrhiza; Humans; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Isoflavones; Mice; Mice, Knockout; Microsomes, Liver; Models, Biological; Molecular Structure; Phenols; Plant Roots; Rats; Rats, Sprague-Dawley; Time Factors; Transfection; Uridine Diphosphate Glucuronic Acid; Verapamil | 2007 |
Role of P-glycoprotein in the intestinal absorption of tanshinone IIA, a major active ingredient in the root of Salvia miltiorrhiza Bunge.
Topics: Abietanes; Adenosine Triphosphate; Administration, Oral; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Caco-2 Cells; Digoxin; Dogs; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Microsomes, Liver; Multidrug Resistance-Associated Proteins; Phenanthrenes; Plant Roots; Probenecid; Propionates; Quinidine; Quinolines; Rats; Rats, Sprague-Dawley; Salvia miltiorrhiza; Temperature; Transfection; Verapamil | 2007 |
What do medical records tell us about potentially harmful co-prescribing?
Topics: Adult; Ambulatory Care; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Digoxin; Diltiazem; Drug Interactions; Drug Utilization Review; Health Maintenance Organizations; Humans; Lovastatin; Medical Audit; Medication Errors; Office Visits; Polypharmacy; United States; Verapamil; Warfarin | 2007 |
Assessment of intestinal absorption of vitexin-2''-o-rhamnoside in hawthorn leaves flavonoids in rat using in situ and in vitro absorption models.
Topics: Animals; Apigenin; ATP Binding Cassette Transporter, Subfamily B; Crataegus; Digoxin; Dose-Response Relationship, Drug; Female; Flavonoids; In Vitro Techniques; Intestinal Absorption; Male; Plant Leaves; Rats; Rats, Sprague-Dawley; Verapamil | 2008 |
In vitro inhibition of CYP3A4 metabolism and P-glycoprotein-mediated transport by trade herbal products.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Herb-Drug Interactions; Humans; Ketoconazole; Plant Extracts; Plant Preparations; Testosterone; Verapamil | 2008 |
Inhibition of P-glycoprotein in Caco-2 cells: effects of herbal remedies frequently used by cancer patients.
Topics: Agaricus; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Calcium Channel Blockers; Cell Survival; Digoxin; Garlic; Humans; Mistletoe; Morinda; Plant Preparations; Soy Foods; Tea; Verapamil | 2008 |
Echinacea purpurea and P-glycoprotein drug transport in Caco-2 cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Biological Transport, Active; Caco-2 Cells; Digoxin; Echinacea; Ethanol; Herb-Drug Interactions; Humans; Plant Extracts; Verapamil | 2009 |
Caco-2 cell methodology and inhibition of the P-glycoprotein transport of digoxin by Aloe vera juice.
Topics: Aloe; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Membrane Permeability; Cell Survival; Digoxin; Humans; Models, Biological; Phytotherapy; Plant Preparations; Quality Control; Verapamil | 2008 |
P-gp inhibition potential in cell-based models: which "calculation" method is the most accurate?
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cell Line, Tumor; Cell Membrane Permeability; Digoxin; Drug Evaluation, Preclinical; HIV Protease Inhibitors; Humans; Indinavir; Kinetics; Propionates; Quinolines; Saquinavir; Verapamil | 2008 |
Studies on cerebral protection of digoxin against ischemia/reperfusion injury in mice.
Topics: Amiloride; Animals; Brain; Brain Ischemia; Calcium; Calcium Signaling; Digoxin; Male; Memory; Mice; Neuroprotective Agents; Psychomotor Performance; Reperfusion Injury; Ruthenium Red; Verapamil | 2009 |
Culture period-dependent change of function and expression of ATP-binding cassette transporters in Caco-2 cells.
Topics: Angiotensin II Type 1 Receptor Blockers; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blotting, Western; Caco-2 Cells; Calcium Channel Blockers; Digoxin; Electric Conductivity; Estrone; Humans; Imidazoles; Leukotriene Antagonists; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Ochratoxins; Propionates; Quinolines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Tight Junctions; Time Factors; Verapamil | 2009 |
Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux.
Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Digoxin; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Female; High-Throughput Screening Assays; Humans; Kinetics; Microinjections; Oocytes; Quinidine; Temperature; Verapamil; Vinblastine; Xenopus laevis | 2010 |
Potent in vitro inhibition of CYP3A4 and P-glycoprotein by Rhodiola rosea.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Baculoviridae; Caco-2 Cells; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Digoxin; DNA, Complementary; Herb-Drug Interactions; Humans; Inhibitory Concentration 50; Ketoconazole; Plant Extracts; Rhodiola; Structure-Activity Relationship; Testosterone; Verapamil | 2010 |
Interaction of angiotensin II type 1 receptor blockers with P-gp substrates in Caco-2 cells and hMDR1-expressing membranes.
Topics: Adenosine Triphosphatases; Angiotensin II Type 1 Receptor Blockers; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Benzoates; Biological Transport; Biphenyl Compounds; Caco-2 Cells; Calcium Channel Blockers; Cardiotonic Agents; Cell Membrane; Digoxin; Drug Interactions; Humans; Irbesartan; Losartan; Telmisartan; Tetrazoles; Verapamil | 2010 |
20(S)-ginsenoside Rh2 noncompetitively inhibits P-glycoprotein in vitro and in vivo: a case for herb-drug interactions.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Digoxin; Etoposide; Ginsenosides; Herb-Drug Interactions; Humans; Ileum; Male; Rats; Rats, Sprague-Dawley; Rhodamine 123; Terfenadine; Verapamil | 2010 |
Tumor necrosis factor alpha increases P-glycoprotein expression in a BME-UV in vitro model of mammary epithelial cells.
Topics: 14-alpha Demethylase Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Calcium Channel Blockers; Cattle; Cell Line, Transformed; Cell Membrane Permeability; Cytokines; Digoxin; Enzyme Inhibitors; Epithelial Cells; Female; Inflammation; Ketoconazole; Mammary Glands, Animal; RNA, Messenger; Tumor Necrosis Factor-alpha; Verapamil | 2010 |
P-glycoprotein is functionally expressed in the placenta-derived bovine caruncular epithelial cell line 1 (BCEC-1).
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Cattle; Cell Line; Cyclosporins; Digoxin; Female; Mice; Neoplasm Proteins; Placenta; Pregnancy; Verapamil | 2011 |
Comparison of drug permeabilities across the blood-retinal barrier, blood-aqueous humor barrier, and blood-brain barrier.
Topics: Animals; Blood-Aqueous Barrier; Blood-Brain Barrier; Blood-Retinal Barrier; Digoxin; Male; Permeability; Pharmacokinetics; Quinidine; Rats; Rats, Sprague-Dawley; Tritium; Verapamil | 2011 |
Intestinal transport of pure diester-type alkaloids from an aconite extract across the Caco-2 cell monolayer model.
Topics: Aconitine; Aconitum; Biological Availability; Biological Transport; Caco-2 Cells; Digoxin; Drug Interactions; Humans; Intestinal Absorption; Phytotherapy; Plant Extracts; Verapamil | 2012 |
Interactions between verapamil and digoxin in Langendorff-perfused rat hearts: the role of inhibition of P-glycoprotein in the heart.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromatography, High Pressure Liquid; Digoxin; Drug Interactions; Female; Heart Rate; Heart Ventricles; In Vitro Techniques; Perfusion; Rats; Rats, Wistar; Ventricular Function, Left; Verapamil | 2010 |
The liver partition coefficient-corrected inhibitory quotient and the pharmacokinetic-pharmacodynamic relationship of directly acting anti-hepatitis C virus agents in humans.
Topics: Animals; Antiviral Agents; Cells, Cultured; Digoxin; Doxorubicin; Hepacivirus; Hepatocytes; Humans; Imipramine; Liver; Male; Mice; Quinidine; Rats; Rats, Sprague-Dawley; Verapamil | 2012 |
[Optimum heart rate - the current goal of cardiovascular therapy. Position statement of the Polish Cardiac Society Working Group on Cardiovascular Drug Therapy].
Topics: Adrenergic beta-Agonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzazepines; Digoxin; Diltiazem; Heart Diseases; Heart Rate; Humans; Hypertension; Ivabradine; Verapamil | 2012 |
Digoxin-associated decrease in parathyroid hormone (PTH) concentrations in patients with atrial fibrillation.
Topics: Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium; Digoxin; Female; Fibroblast Growth Factor-23; Humans; Male; Middle Aged; Parathyroid Hormone; Verapamil | 2013 |
Keratinocyte growth factor-2 stimulates P-glycoprotein expression and function in intestinal epithelial cells.
Topics: ATP Binding Cassette Transporter 1; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biotransformation; Caco-2 Cells; Digoxin; Endothelial Cells; Fibroblast Growth Factor 10; Flavonoids; Gene Expression Regulation; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; MAP Kinase Signaling System; Pyrimidines; Receptors, Fibroblast Growth Factor; RNA, Messenger; Urea; Verapamil | 2013 |
Potential role for human P-glycoprotein in the transport of lacosamide.
Topics: Acetamides; Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Line; Digoxin; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gene Expression Regulation; Humans; Lacosamide; Quinolines; Rhodamine 123; RNA, Messenger; Swine; Time Factors; Transfection; Tritium; Verapamil | 2013 |
Application of permeability-limited physiologically-based pharmacokinetic models: part II - prediction of P-glycoprotein mediated drug-drug interactions with digoxin.
Topics: Adjuvants, Anesthesia; Anti-Arrhythmia Agents; ATP Binding Cassette Transporter, Subfamily B; Computer Simulation; Digoxin; Drug Interactions; Enzyme Inhibitors; Humans; Midazolam; Models, Biological; Permeability; Rifampin; Verapamil | 2013 |
In vitro to in vivo evidence of the inhibitor characteristics of Schisandra lignans toward P-glycoprotein.
Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Caco-2 Cells; Digoxin; Herb-Drug Interactions; Humans; Intestinal Mucosa; Intestines; Lignans; Plant Extracts; Rats; Schisandra; Verapamil; Vincristine | 2013 |
Altered brain uptake of therapeutics in a triple transgenic mouse model of Alzheimer's disease.
Topics: Alzheimer Disease; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Brain; Digoxin; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Pharmacokinetics; Propranolol; Sucrose; Transgenes; Vasodilator Agents; Verapamil | 2013 |
Acetaminophen inhibits intestinal p-glycoprotein transport activity.
Topics: Acetaminophen; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Cell Line, Tumor; Cyclosporins; Digoxin; Enterocytes; Hep G2 Cells; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Male; Permeability; Rats; Rats, Wistar; Rhodamine 123; Verapamil | 2013 |
Effect of P-glycoprotein on the rat intestinal permeability and metabolism of the BDDCS class 1 drug verapamil.
Topics: Animals; Atorvastatin; ATP Binding Cassette Transporter, Subfamily B, Member 1; Digoxin; Heptanoic Acids; Intestinal Absorption; Pyrroles; Rats; Rats, Sprague-Dawley; Verapamil | 2013 |
Physiologically based pharmacokinetic modelling and in vivo [I]/K(i) accurately predict P-glycoprotein-mediated drug-drug interactions with dabigatran etexilate.
Topics: Amiodarone; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; beta-Alanine; Clarithromycin; Dabigatran; Digoxin; Dronedarone; Drug Interactions; Humans; Models, Biological; Pyridines; Quinidine; Verapamil | 2014 |
Inhibitory effects of herbal constituents on P-glycoprotein in vitro and in vivo: herb-drug interactions mediated via P-gp.
Topics: Animals; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Cell Line, Tumor; Cytochrome P-450 CYP3A; Digoxin; Diterpenes; Emodin; Ginsenosides; Glycyrrhetinic Acid; Herb-Drug Interactions; Humans; Male; Microsomes, Liver; Protein Conformation; Rats; Verapamil | 2014 |
Impact of P-glycoprotein on blood-retinal barrier permeability: comparison of blood-aqueous humor and blood-brain barrier using mdr1a knockout rats.
Topics: Animals; Aqueous Humor; ATP Binding Cassette Transporter, Subfamily B; Biological Transport, Active; Blood-Aqueous Barrier; Blood-Brain Barrier; Blood-Retinal Barrier; Brain; Calcium Channel Blockers; Capillary Permeability; Digoxin; Gene Knockout Techniques; Male; Quinidine; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Retina; Verapamil; Voltage-Gated Sodium Channel Blockers | 2014 |
Cytotoxicity of cardiotonic steroids in sensitive and multidrug-resistant leukemia cells and the link with Na(+)/K(+)-ATPase.
Topics: Antineoplastic Agents; Bufanolides; Cardiac Glycosides; Cell Line, Tumor; Cell Survival; Digoxin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Gene Expression; Humans; Leukocytes, Mononuclear; Molecular Docking Simulation; Primary Cell Culture; Quantitative Structure-Activity Relationship; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Verapamil | 2015 |
Drug-Drug Interactions of a Novel κ-Opioid Receptor Agonist, Nalfurafine Hydrochloride, Involving the P-Glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Blood-Brain Barrier; Brain; Cell Line; Digoxin; Drug Interactions; Humans; LLC-PK1 Cells; Male; Mice; Mice, Inbred ICR; Morphinans; Permeability; Receptors, Opioid, kappa; Spiro Compounds; Swine; Verapamil | 2016 |
Transport of digoxin-loaded polymeric nanoparticles across BeWo cells, an in vitro model of human placental trophoblast.
Topics: Cell Line; Cell Survival; Digoxin; Female; Humans; Lactic Acid; Models, Biological; Nanoparticles; Placenta; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Pregnancy; Trophoblasts; Verapamil | 2015 |
Unravelling the complex drug-drug interactions of the cardiovascular drugs, verapamil and digoxin, with P-glycoprotein.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport, Active; Digoxin; Drug Interactions; Mice; Models, Chemical; Verapamil | 2016 |
Usefulness of A Model-Based Approach for Estimating In Vitro P-Glycoprotein Inhibition Potency in a Transcellular Transport Assay.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Humans; Models, Biological; Transcytosis; Verapamil | 2016 |
Quantitative Targeted Absolute Proteomics of Transporters and Pharmacoproteomics-Based Reconstruction of P-Glycoprotein Function in Mouse Small Intestine.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Dexamethasone; Digoxin; Duodenum; Ileum; Intestinal Absorption; Intestine, Small; Jejunum; Loperamide; Mice; Mice, Knockout; Proteomics; Quinidine; Verapamil; Vinblastine | 2016 |
Usefulness of cardiotoxicity assessment using calcium transient in human induced pluripotent stem cell-derived cardiomyocytes.
Topics: Arrhythmias, Cardiac; Astemizole; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Cell Differentiation; Cells, Cultured; Digoxin; Dose-Response Relationship, Drug; Drug Discovery; Fluoroquinolones; Induced Pluripotent Stem Cells; Isoproterenol; Moxifloxacin; Myocardial Contraction; Myocytes, Cardiac; Propranolol; Toxicity Tests; Verapamil | 2017 |
[Validation of in situ single pass perfusion model based on P-gp].
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Digoxin; Ileum; Intestinal Absorption; Perfusion; Rats; Verapamil | 2017 |
Hypermagnesuria in Humans Following Acute Intravenous Administration of Digoxin.
Topics: Administration, Intravenous; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Atrial Fibrillation; Digoxin; Female; Heart Rate; Humans; Kidney Function Tests; Magnesium; Male; Sodium-Potassium-Exchanging ATPase; Verapamil | 2018 |
Beta-blocker Use in Moderate and Severe Chronic Obstructive Pulmonary Disease.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bisoprolol; Case-Control Studies; Digoxin; Disease Progression; Forced Expiratory Volume; Humans; Metoprolol; Nebivolol; Pulmonary Disease, Chronic Obstructive; Severity of Illness Index; Verapamil; Vital Capacity | 2019 |
Effective reconstruction of functional organotypic kidney spheroid for in vitro nephrotoxicity studies.
Topics: Acyclovir; Animals; Biological Transport; Biomarkers; Bone Morphogenetic Protein 7; Carrier Proteins; Cell Culture Techniques; Cell Line, Transformed; Cell Lineage; Cimetidine; Cisplatin; Cyclic AMP; Cyclosporine; Digoxin; Doxorubicin; Drug Evaluation, Preclinical; Endocytosis; Extracellular Matrix; gamma-Glutamyltransferase; Humans; Kidney; Mice; Spheroids, Cellular; Toxicity Tests; Verapamil | 2019 |
The cardiac work-loop technique: An in vitro model for identifying and profiling drug-induced changes in inotropy using rat papillary muscles.
Topics: Animals; Anthropometry; Atenolol; Cardiotonic Agents; Digoxin; Dobutamine; Electric Stimulation; Flecainide; In Vitro Techniques; Isometric Contraction; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Rats; Rats, Sprague-Dawley; Stress, Mechanical; Verapamil | 2020 |
PBPK modeling of CYP3A and P-gp substrates to predict drug-drug interactions in patients undergoing Roux-en-Y gastric bypass surgery.
Topics: Acetaminophen; Administration, Oral; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Digoxin; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Gastric Bypass; Gastrointestinal Absorption; Hepatobiliary Elimination; Humans; Intestinal Elimination; Metabolic Clearance Rate; Midazolam; Models, Biological; Obesity, Morbid; Postoperative Period; Triazoles; Verapamil | 2020 |
Physiologically-based pharmacokinetic modeling to evaluate in vitro-to-in vivo extrapolation for intestinal P-glycoprotein inhibition.
Topics: Adult; Area Under Curve; ATP Binding Cassette Transporter, Subfamily B, Member 1; Computer Simulation; Dabigatran; Digoxin; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Intestines; Itraconazole; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Quinidine; Verapamil; Young Adult | 2022 |
Evaluation of the Effect of Isobutyl Paraben and 2-ethyl Hexyl Paraben on P-glycoprotein Functional Expression in Rats: A Pharmacokinetic Study.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Digoxin; Parabens; Pharmaceutical Preparations; Rats; RNA, Messenger; Verapamil | 2022 |
Characterization of P-glycoprotein orthologs from human, sheep, pig, dog, and cat.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cats; Digoxin; Dogs; HEK293 Cells; Humans; Mice; Sheep; Swine; Verapamil | 2023 |