verapamil has been researched along with deuterium in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Higgins, J; Hoffman, DJ | 1 |
| Echizen, H; Eichelbaum, M; Schmidt, E; Vogelgesang, B | 2 |
| Eichelbaum, M; Somogyi, A | 1 |
| Dengler, HJ; Eichelbaum, M; Somogyi, A; von Unruh, GE | 2 |
| Darbar, D; Dell'Orto, S; Eichelbaum, M; Fromm, MF; Kim, RB; Kroemer, HK; Roden, DM | 1 |
| Eichelbaum, M; Hofmann, U; Schönberger, F; von Richter, O | 1 |
| Cai, L; He, K; Liu, H; Shi, Q; Woolf, TF | 1 |
| Higashino, H; Kataoka, M; Kojima, C; Minami, K; Mutaguchi, K; Sakuma, S; Togashi, K; Ueda, K; Yamashita, S | 1 |
1 trial(s) available for verapamil and deuterium
| Article | Year |
|---|---|
Modulation by dietary salt of verapamil disposition in humans.
Topics: Administration, Oral; Adult; Deuterium; Diet, Sodium-Restricted; Female; Humans; Infusions, Intravenous; Male; Sodium Chloride, Dietary; Time Factors; Verapamil | 1998 |
9 other study(ies) available for verapamil and deuterium
| Article | Year |
|---|---|
Resolution of verapamil from heptadeuteroverapamil and their quantitation in serum using capillary gas chromatography.
Topics: Chromatography, Gas; Deuterium; Humans; Indicators and Reagents; Isotope Labeling; Kinetics; Male; Verapamil | 1986 |
Stereoselective first-pass metabolism of highly cleared drugs: studies of the bioavailability of L- and D-verapamil examined with a stable isotope technique.
Topics: Adult; Biological Availability; Deuterium; Half-Life; Humans; Male; Stereoisomerism; Verapamil | 1984 |
Inter- and intra-subject variation in the first-pass elimination of highly cleared drugs during chronic dosing. Studies with deuterated verapamil.
Topics: Administration, Oral; Adult; Biological Availability; Deuterium; Female; Half-Life; Humans; Kinetics; Male; Time Factors; Verapamil | 1984 |
Superiority of stable isotope techniques in the assessment of the bioavailability of drugs undergoing extensive first pass elimination. Studies of the relative bioavailability of verapamil tablets.
Topics: Adult; Biological Availability; Deuterium; Female; Humans; Kinetics; Male; Tablets; Verapamil | 1981 |
Simultaneous determination of the intravenous and oral pharmacokinetic parameters of D,L-verapamil using stable isotope-labelled verapamil.
Topics: Administration, Oral; Adult; Biological Availability; Deuterium; Female; Humans; Injections, Intravenous; Kinetics; Liver; Male; Verapamil | 1981 |
Rapid and highly sensitive method for the determination of verapamil, [2H7]verapamil and metabolites in biological fluids by liquid chromatography-mass spectrometry.
Topics: Body Fluids; Chromatography, High Pressure Liquid; Deuterium; Humans; Intestinal Mucosa; Mass Spectrometry; Quality Control; Sensitivity and Specificity; Verapamil | 2000 |
Stereoselective first-pass metabolism of highly cleared drugs: studies of the bioavailability of L- and D-verapamil examined with a stable isotope technique. 1984.
Topics: Biological Availability; Calcium Channel Blockers; Deuterium; History, 20th Century; Humans; Male; Stereoisomerism; Verapamil | 2004 |
Inhibition of MDR3 Activity in Human Hepatocytes by Drugs Associated with Liver Injury.
Topics: ATP Binding Cassette Transporter, Subfamily B; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Deuterium; Hepatocytes; Humans; Itraconazole; Phosphatidylcholines; Tandem Mass Spectrometry; Taurocholic Acid; Verapamil | 2015 |
Quantitative analysis of pharmacokinetic profiles of verapamil and drug-drug interactions induced by a CYP inhibitor using a stable isotope-labeled compound.
Topics: Administration, Intravenous; Administration, Oral; Animals; Biological Availability; Cytochrome P-450 Enzyme Inhibitors; Deuterium; Drug Interactions; Male; Microsomes, Liver; Rats, Wistar; Triazoles; Verapamil | 2016 |