verapamil has been researched along with dantrolene in 70 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 36 (51.43) | 18.7374 |
| 1990's | 20 (28.57) | 18.2507 |
| 2000's | 8 (11.43) | 29.6817 |
| 2010's | 6 (8.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bondi, AY | 1 |
| Duncan, CJ; Publicover, SJ | 1 |
| Cohen, J; Gutman, Y | 1 |
| Chujyo, N; Sakato, M; Sekiguchi, S; Takahashi, S | 1 |
| Burchés, E; Cortijo, J; Morcillo, EJ; Orón, JD; Ortiz, JL | 1 |
| Belhage, B; Hansen, GH; Kater, SB; Rehder, V; Schousboe, A | 1 |
| Frandsen, A; Schousboe, A | 1 |
| Raij, L; Shultz, PJ | 1 |
| Frevert, J; Hoyt, DB; Junger, WG; Loomis, WH; Ozkan, AN | 1 |
| Forsyth, GW; Maenz, DD; Wong, PH | 1 |
| Bégin-Heick, N; Black, MA; Fournier, LA; Heick, HM | 1 |
| Dharmsathaphorn, K; Donowitz, M; Mikkelsen, R; Reinlib, L; Zahniser, D | 1 |
| Changeux, JP; Devillers-Thiéry, A; Dubreuil, C; Fontaine, B; Klarsfeld, A; Laufer, R | 1 |
| Jones, HM; Rush, ME; Simpson, WG; Vernon, ME | 1 |
| Berger, SG; Hofmann, A; Waser, PG | 1 |
| Denborough, MA; Foster, PS; Hopkinson, KC | 1 |
| López, JR; López, MJ; Sánchez, V | 1 |
| Blaha, M; Bowers, W; Castro, I; Daum, P; Leav, I; Stevens, C | 1 |
| Degnan, KJ; May, SA | 1 |
| Avioli, LV; Civitelli, R; Halstead, LR; Hruska, KA; Reid, IR | 1 |
| Cortijo, J; Esplugues, J; Morcillo, EJ; Ortiz, JL; Perpiñá, M; Sanz, C | 1 |
| Kim, JK; Meyer-Lehnert, H; Schrier, RW; Takeda, K | 2 |
| Port, JD; San Juan, AC; Wong, KC | 1 |
| Rubin, AS; Zablocki, AD | 1 |
| Nakayama, K | 1 |
| Althaus, JS; Durbin, CG; Fisher, NA; Lynch, C; Veselis, RA | 1 |
| Bezer, G | 1 |
| Foldes, FF; Gallant, EM; Gronert, GA; Rempel, WE | 1 |
| Al-Shanableh, JS; Keilani, MR | 1 |
| Callanan, KM; Keenan, AK | 1 |
| Drzewiecki, G; Middleton, E; Triggle, D | 1 |
| Hudgson, P; Lane, RJ; Turnbull, DM; Walton, J | 1 |
| Bonifacio, V; Fabbri, A; Fraioli, F; Gnessi, L; Moretti, C; Panerai, AE; Silvestroni, L | 1 |
| Ishii, K; Kato, R; Sasakawa, N; Yamamoto, S | 1 |
| Corke, BC; Heath, KR; Kates, RA; Norfleet, EA; Saltzman, LS | 1 |
| Bittar, EE; Helmer, P; Rusy, B | 1 |
| Dehpour, AR; Mahmoudian, M; Mofakham, S | 1 |
| Dehpour, AR; Mahmoudian, M | 1 |
| Oriowo, MA | 1 |
| Nagai, T; Takauji, M; Tsutsu-Ura, M | 1 |
| Cho, KP; Eun, YA; Kim, DC; Kim, HI; Kim, KW; Kim, YH | 1 |
| Dehpour, AR; Delfan, A; Ghafourifar, P; Rastegar, H; Samini, M | 1 |
| Ganguly, NK; Kanwar, RK; Kumar, L; Panigrahi, D; Rakesh, J; Walia, BN | 1 |
| Alimian, M; Behbahani, NR; Dehpour, AR; Tajkhorshid, E | 1 |
| Mollitt, DL; Todd, JC | 1 |
| Cortijo, J; Morcillo, EJ; Orón, JD; Perpiñá, M | 1 |
| Hayashi, T; Kagaya, A; Motohashi, N; Yamawaki, S | 1 |
| Benders, AA; Bindels, RJ; Busch, HF; Jongen, PJ; Oosterhof, A; Smit, LM; Veerkamp, JH; Wevers, RA | 1 |
| Chihara, K; Fukase, M; Kanatani, M; Kano, J; Kobayashi, T; Sugimoto, T; Yamaguchi, T | 1 |
| Gumà, A; Palacín, M; Testar, X; Viñals, F; Zorzano, A | 1 |
| Benders, AA; Veerkamp, JH; Wevers, RA | 1 |
| Frandsen, A; Pomés, A; Rodríguez-Farré, E; Rosa, R; Sanfeliu, C; Schousboe, A; Suñol, C | 1 |
| Dhawan, V; Ganguly, NK; Kaur, T; Singh, S | 1 |
| Ganguly, NK; Gorowara, S; Sapru, S | 1 |
| Ronca, G; Ronca-Testoni, S; Yu, G; Zucchi, R | 1 |
| Salceda, R; Sánchez-Chávez, G | 1 |
| Haake, N; Hirt, S; Meissner, A; Min, JY; Simon, R | 1 |
| Makuck, RF; Porter, GA; Rivkees, SA | 1 |
| Açikel, M; Büyükokuroğlu, ME; Gepdiremen, A; Göçer, F | 1 |
| Chakrabarti, SK; Lemieux, N; M'Bemba-Meka, P | 1 |
| Kaku, K; Katsura, M; Matsuda, M; Ohkuma, S; Shigeto, M | 1 |
| Baxter, RC; Bolitho, C; Marsh, DJ; Mertens-Walker, I | 1 |
| Gieseg, SP; Whiteman, M; Yang, YT | 1 |
| Campos, EC; Celes, MR; da Silva, JS; Figueiredo, MJ; Freitas, AC; Malvestio, LM; Prado, CM; Rossi, MA; Spray, DC; Suadicani, SO; Tanowitz, HB | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
1 review(s) available for verapamil and dantrolene
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 trial(s) available for verapamil and dantrolene
| Article | Year |
|---|---|
Trials of verapamil and dantrolene sodium in McArdle disease.
Topics: Calcium; Clinical Trials as Topic; Dantrolene; Glycogen Storage Disease; Glycogen Storage Disease Type V; Humans; Verapamil | 1984 |
68 other study(ies) available for verapamil and dantrolene
| Article | Year |
|---|---|
Effects of verapamil on excitation-contraction coupling in frog sartorius muscle.
Topics: Animals; Anura; Caffeine; Calcium; Dantrolene; Drug Interactions; Electric Stimulation; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscles; Potassium; Procaine; Rana pipiens; Verapamil | 1978 |
The action of verapamil on the rate of spontaneous release of transmitter at the frog neuromuscular junction.
Topics: Action Potentials; Animals; Anura; Calcium; Dantrolene; Female; Gallopamil; In Vitro Techniques; Male; Motor Endplate; Neuromuscular Junction; Neurotransmitter Agents; Rana pipiens; Temperature; Theophylline; Verapamil | 1979 |
Effects of verapamil, dantrolene and lanthanum on catecholamine release from rat adrenal medulla.
Topics: Adrenal Medulla; Animals; Catecholamines; Dantrolene; Hydantoins; In Vitro Techniques; Lanthanum; Male; Potassium Chloride; Rats; Theophylline; Tyramine; Verapamil | 1979 |
[Simulation of K-contracture curve in smooth muscle (author's transl)].
Topics: Animals; Calcium; Colon; Dantrolene; Female; Guinea Pigs; In Vitro Techniques; Male; Models, Biological; Muscle Contraction; Muscle, Smooth; Potassium; Verapamil | 1979 |
Effects of calcium antagonists on rat normal and skinned fundus.
Topics: Animals; Calcium Channel Blockers; Cinnarizine; Dantrolene; Female; Gastric Fundus; Guinea Pigs; In Vitro Techniques; Male; Muscle, Smooth; Rats; Rats, Inbred Strains; Trifluoperazine; Verapamil | 1992 |
3H-D-aspartate release from cerebellar granule neurons is differentially regulated by glutamate- and K(+)-stimulation.
Topics: Animals; Aspartic Acid; Calcium; Cerebellum; Dantrolene; Glutamates; Glutamic Acid; Neurons; Nocodazole; Potassium; Rats; Rats, Wistar; Verapamil | 1992 |
Mobilization of dantrolene-sensitive intracellular calcium pools is involved in the cytotoxicity induced by quisqualate and N-methyl-D-aspartate but not by 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionate and kainate in cultured cerebral cortical neu
Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Calcium; Cell Survival; Cells, Cultured; Cerebral Cortex; Dantrolene; Glutamates; Glutamic Acid; Ibotenic Acid; In Vitro Techniques; Kainic Acid; Mice; N-Methylaspartate; Neurotoxins; Quisqualic Acid; Verapamil | 1992 |
Inhibition of human mesangial cell proliferation by calcium channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Calcium Channel Blockers; Cell Division; Cells, Cultured; Dantrolene; Diltiazem; Glomerular Mesangium; Humans; Nifedipine; Platelet-Derived Growth Factor; Thrombin; Thymidine; Verapamil | 1990 |
Alteration in Ca2+ homeostasis by a trauma peptide.
Topics: Calcium; Calcium Channel Blockers; Dantrolene; Fibronectins; Glycopeptides; Homeostasis; Humans; Inositol Phosphates; Monocytes; Nifedipine; Prostaglandins E; Verapamil; Wounds and Injuries | 1991 |
Calcium mediation of the pig jejunal secretory response.
Topics: Animals; Bacterial Toxins; Calcimycin; Calcium; Cell Membrane Permeability; Chlorpromazine; Dantrolene; Egtazic Acid; Enterotoxins; Escherichia coli Proteins; Intestinal Mucosa; Ion Channels; Jejunum; Membrane Potentials; Swine; Theophylline; Verapamil | 1985 |
Different insulin-secretory responses to calcium-channel blockers in islets of lean and obese (ob/ob) mice.
Topics: Animals; Colforsin; Dantrolene; Glucose; Insulin; Insulin Secretion; Ion Channels; Islets of Langerhans; Male; Mice; Mice, Obese; Nifedipine; Obesity; Stimulation, Chemical; Trifluoperazine; Verapamil | 1988 |
Carbachol-induced cytosolic free Ca2+ increases in T84 colonic cells seen by microfluorimetry.
Topics: Atropine; Calcium; Carbachol; Cell Line; Colonic Neoplasms; Cytosol; Dantrolene; Egtazic Acid; Humans; Kinetics; Microscopy, Fluorescence; Tumor Cells, Cultured; Verapamil | 1989 |
Regulation of muscle AChR alpha subunit gene expression by electrical activity: involvement of protein kinase C and Ca2+.
Topics: Animals; Calcimycin; Calcium; Cells, Cultured; Chick Embryo; Dantrolene; Gene Expression Regulation; Macromolecular Substances; Muscles; Protein Kinase C; Receptors, Cholinergic; RNA, Messenger; Tetradecanoylphorbol Acetate; Tetrodotoxin; Transcription, Genetic; Verapamil | 1989 |
The role of calcium in gonadotropin-releasing hormone induction of follicle-stimulating hormone release by the pituitary gonadotrope.
Topics: Animals; Calcimycin; Calcium; Cyclic AMP; Cyclic GMP; Dantrolene; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Kinetics; Organ Culture Techniques; Ovariectomy; Pituitary Gland, Anterior; Rats; Rats, Inbred Strains; Trifluoperazine; Verapamil | 1989 |
Effects of new 4-aminopyridine derivatives on neuromuscular transmission and on smooth muscle contractility.
Topics: Aminopyridines; Animals; Botulinum Toxins; Chemical Phenomena; Chemistry, Physical; Dantrolene; Guinea Pigs; Ileum; In Vitro Techniques; Male; Mice; Mice, Inbred ICR; Muscle Contraction; Muscle, Smooth; Neuromuscular Junction; Phrenic Nerve; Respiratory Muscles; Synaptic Transmission; Trifluoperazine; Verapamil | 1989 |
Effect of diltiazem, verapamil and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible human skeletal muscle.
Topics: Caffeine; Dantrolene; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Verapamil | 1989 |
Dysfunction in myoplasmic Ca(2+) homeostasis in neuroleptic malignant syndrome.
Topics: Calcium; Dantrolene; Homeostasis; Humans; Muscles; Neuroleptic Malignant Syndrome; Verapamil | 1989 |
Calcium antagonists and heat-induced hepatic injury.
Topics: Animals; Aspartate Aminotransferases; Bile; Calcium Channel Blockers; Dantrolene; Hyperthermia, Induced; In Vitro Techniques; Liver; Male; Microscopy, Electron; Nifedipine; Perfusion; Rats; Verapamil | 1987 |
Converging adrenergic and cholinergic mechanisms in the inhibition of Cl secretion in fish opercular epithelium.
Topics: Acetylcholine; Animals; Calcium; Chlorine; Clonidine; Cyclic AMP; Dantrolene; Epithelium; Female; Fishes; Killifishes; Male; Receptors, Adrenergic; Receptors, Cholinergic; Trifluoperazine; Verapamil | 1985 |
Parathyroid hormone acutely elevates intracellular calcium in osteoblastlike cells.
Topics: Animals; Bucladesine; Calcium; Cell Line; Dantrolene; Gallic Acid; Intracellular Membranes; Osmolar Concentration; Osteoblasts; Parathyroid Hormone; Verapamil | 1987 |
The spasmogenic effect of caffeine in trachealis isolated from control and actively sensitized guinea-pigs.
Topics: Animals; Caffeine; Calcium; Dantrolene; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Temperature; Trachea; Trifluoperazine; Verapamil | 1988 |
Effect of angiotensin II on Ca2+ kinetics and contraction in cultured rat glomerular mesangial cells.
Topics: Aminoquinolines; Angiotensin II; Animals; Calcium; Cells, Cultured; Dantrolene; Glomerular Mesangium; Kinetics; Rats; Rats, Inbred Strains; Saralasin; Verapamil | 1988 |
AVP-induced Ca fluxes and contraction of rat glomerular mesangial cells.
Topics: Aminoquinolines; Animals; Arginine Vasopressin; Calcium; Cells, Cultured; Dantrolene; Glomerular Mesangium; Lanthanum; Rats; Rats, Inbred Strains; Verapamil | 1988 |
Hyperkalemia after dantrolene and verapamil-dantrolene administration in dogs.
Topics: Animals; Blood Pressure; Calcium; Cardiac Output; Dantrolene; Dogs; Drug Interactions; Heart Rate; Hyperkalemia; Malignant Hyperthermia; Sodium; Vascular Resistance; Verapamil | 1988 |
Hyperkalemia, verapamil, and dantrolene.
Topics: Colectomy; Colonic Neoplasms; Coronary Disease; Dantrolene; Drug Interactions; Humans; Hyperkalemia; Male; Malignant Hyperthermia; Middle Aged; Postoperative Period; Verapamil | 1987 |
Verapamil-resistant contractile activation of isolated coronary artery produced by hyperosmolar solutions.
Topics: Animals; Calcium; Coronary Vessels; Dantrolene; Drug Resistance; Hypertonic Solutions; In Vitro Techniques; Mannitol; Potassium; Procaine; Saline Solution, Hypertonic; Strophanthins; Sucrose; Swine; Vasoconstriction; Verapamil | 1985 |
Effects of dantrolene and verapamil on atrioventricular conduction and cardiovascular performance in dogs.
Topics: Animals; Dantrolene; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Heart Conduction System; Hemodynamics; Muscle Contraction; Myocardial Contraction; Verapamil | 1986 |
Dantrolene sodium intravenous--verapamil.
Topics: Animals; Cardiovascular Diseases; Dantrolene; Drug Interactions; Swine; Verapamil | 1985 |
Verapamil is not a therapeutic adjunct to dantrolene in porcine malignant hyperthermia.
Topics: Anesthesia, Inhalation; Animals; Blood Gas Analysis; Blood Pressure; Dantrolene; Drug Synergism; Halothane; Heart Rate; Infusions, Parenteral; Malignant Hyperthermia; Muscle Contraction; Succinylcholine; Swine; Verapamil | 1985 |
Verapamil and malignant hyperthermia--case reports.
Topics: Adult; Calcium; Child; Child, Preschool; Dantrolene; Drug Therapy, Combination; Female; Humans; Male; Malignant Hyperthermia; Muscles; Sarcoplasmic Reticulum; Verapamil | 1985 |
Differential effects of D600, nifedipine and dantrolene sodium on excitation-secretion coupling and presynaptic beta-adrenoceptor responses in rat atria.
Topics: Animals; Calcium; Calcium Channel Blockers; Dantrolene; Electric Stimulation; Female; Gallopamil; Heart; Heart Atria; In Vitro Techniques; Isoproterenol; Male; Manganese; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Verapamil | 1984 |
Effects of smooth muscle calcium antagonists on human basophil histamine release.
Topics: Basophils; Calcium; Dantrolene; Gallic Acid; Gallopamil; Histamine Release; Humans; Muscle Contraction; Muscle, Smooth; Nifedipine; Quercetin; Verapamil | 1981 |
Salmon calcitonin inhibits human sperm motility in vitro.
Topics: Adult; Animals; Calcitonin; Calcium; Dantrolene; Dose-Response Relationship, Drug; Humans; Male; Salmon; Sperm Motility; Spermatozoa; Verapamil | 1984 |
Inhibition of calcium uptake and catecholamine release by 8-(N,N-diethylamino)-octyl-3,4,5-trimethoxybenzoate hydrochloride (TMB-8) in cultured bovine adrenal chromaffin cells.
Topics: Adrenal Glands; Animals; Calcium; Calcium Channel Blockers; Carbachol; Catecholamines; Cattle; Cells, Cultured; Chromaffin Granules; Chromaffin System; Dantrolene; Gallic Acid; Verapamil | 1984 |
Hyperkalemia and cardiovascular collapse after verapamil and dantrolene administration in swine.
Topics: Animals; Dantrolene; Drug Evaluation, Preclinical; Drug Interactions; Electric Stimulation; Heart Arrest; Hemodynamics; Hyperkalemia; Infusions, Parenteral; Injections, Intravenous; Neuromuscular Junction; Random Allocation; Swine; Verapamil | 1984 |
Sensitivity to halothane of the sodium efflux in single barnacle muscle fibers.
Topics: Animals; Calcium; Dantrolene; Egtazic Acid; Halothane; Membrane Potentials; Muscles; Ouabain; Procaine; Sodium; Thoracica; Verapamil | 1981 |
In vitro binding of dantrolene to sarcoplasmic reticulum of rabbit skeletal muscle.
Topics: Animals; Dantrolene; Female; Fluorescence; In Vitro Techniques; Male; Muscles; Rabbits; Sarcoplasmic Reticulum; Verapamil | 1982 |
In vitro binding of dantrolene to bovine serum albumin and rabbit red blood cell ghosts.
Topics: Animals; Binding, Competitive; Cattle; Dantrolene; Erythrocyte Membrane; Erythrocytes; In Vitro Techniques; Kinetics; Protein Binding; Rabbits; Serum Albumin, Bovine; Verapamil | 1982 |
Differential effect of verapamil on noradrenaline, carbachol, tyramine and 5-hydroxytryptamine induced contractions of the rat anococcygeus muscle.
Topics: Animals; Calcium; Carbachol; Dantrolene; Drug Interactions; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Norepinephrine; Rats; Serotonin; Tyramine; Verapamil | 1982 |
Biphasic potassium contractures in frog single twitch muscle fibers and effects of various agents on the contractures.
Topics: Animals; Calcium; Dantrolene; In Vitro Techniques; Lincomycin; Manganese; Muscle Contraction; Potassium; Procaine; Ranidae; Verapamil | 1980 |
Ca2+-dependent and -independent mechanisms of ischaemia-evoked release of [3H]-dopamine from rat striatal slices.
Topics: Animals; Brain Ischemia; Calcium; Calcium Channel Blockers; Corpus Striatum; Culture Techniques; Cyclopentanes; Dantrolene; Dizocilpine Maleate; Dopamine; Ketamine; Magnesium Sulfate; Nomifensine; omega-Conotoxin GVIA; Peptides; Quinoxalines; Rats; Tetrodotoxin; Verapamil | 1995 |
Comparison of various calcium channel blockers on guinea-pig isolated common bile duct.
Topics: Animals; Calcium Channel Blockers; Common Bile Duct; Dantrolene; Diltiazem; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Male; Nifedipine; Verapamil | 1994 |
Calcium and protein kinase C play an important role in Campylobacter jejuni-induced changes in Na+ and Cl- transport in rat ileum in vitro.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Calcimycin; Calcium; Calmodulin; Campylobacter Infections; Campylobacter jejuni; Chlorides; Cyclic AMP; Dantrolene; Diarrhea; Enzyme Activation; Ileum; In Vitro Techniques; Ion Transport; Isoquinolines; Male; Piperazines; Protein Kinase C; Rats; Rats, Wistar; Sodium; Tetradecanoylphorbol Acetate; Verapamil | 1995 |
Different calcium dependencies of contractile activity of prostatic and epididymal portions of rat vas deferens.
Topics: Animals; Calcium; Calcium Channel Blockers; Dantrolene; Electric Stimulation; Epididymis; Extracellular Space; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Prostate; Rats; Vas Deferens; Verapamil | 1995 |
Effect of sepsis on erythrocyte intracellular calcium homeostasis.
Topics: Adenosine; Adenosine Triphosphate; Adolescent; Adult; Aged; Calcium; Dantrolene; Endotoxins; Erythrocytes; Escherichia coli; Female; Homeostasis; Humans; Male; Middle Aged; Prospective Studies; Sepsis; Verapamil | 1995 |
Effects of alkylxanthines on contractility of diaphragm fibres isolated from normal and sensitized guinea-pigs.
Topics: Adenosine; Animals; Bronchodilator Agents; Caffeine; Calcium; Culture Media; Dantrolene; Diaphragm; Electric Stimulation; Extracellular Space; Female; Guinea Pigs; Immunization; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Serum Albumin, Bovine; Theobromine; Theophylline; Verapamil; Xanthines | 1993 |
Possible mechanism of dantrolene stabilization of cultured neuroblastoma cell plasma membranes.
Topics: Animals; Calcium; Cell Membrane; Cell Membrane Permeability; Dantrolene; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Fluorescence; Membrane Fluidity; Mice; Neuroblastoma; p-Methoxy-N-methylphenethylamine; Tumor Cells, Cultured; Verapamil | 1994 |
Ca2+ homeostasis in Brody's disease. A study in skeletal muscle and cultured muscle cells and the effects of dantrolene an verapamil.
Topics: Acetylcholine; Adolescent; Adult; Calcium; Calcium-Transporting ATPases; Cells, Cultured; Child; Dantrolene; Female; Homeostasis; Humans; Male; Middle Aged; Muscles; Myotonia; Sarcoplasmic Reticulum; Sodium-Potassium-Exchanging ATPase; Verapamil | 1994 |
IGF-I mediates the stimulatory effect of high calcium concentration on osteoblastic cell proliferation.
Topics: 3T3 Cells; Animals; Antibodies; Calcium; Calcium Channel Blockers; Cell Division; Clone Cells; Cycloheximide; Dantrolene; Diltiazem; DNA; Dose-Response Relationship, Drug; Insulin-Like Growth Factor I; Kinetics; Magnesium; Mice; Nifedipine; Osteoblasts; Receptor, IGF Type 1; Transcription, Genetic; Verapamil | 1994 |
Regulation of System A amino-acid transport activity by phospholipase C and cAMP-inducing agents in skeletal muscle: modulation of insulin action.
Topics: 3-O-Methylglucose; Amino Acids; Animals; beta-Alanine; Biological Transport; Cholera Toxin; Cyclic AMP; Dantrolene; Glucose; In Vitro Techniques; Insulin; Isoproterenol; Male; Methylglucosides; Muscles; Rats; Rats, Wistar; Type C Phospholipases; Verapamil | 1993 |
Ion transport in human skeletal muscle cells: disturbances in myotonic dystrophy and Brody's disease.
Topics: Acetylcholine; Adolescent; Adult; Biological Transport, Active; Calcium; Calcium Channel Blockers; Cells, Cultured; Dantrolene; Female; Homeostasis; Humans; Immunohistochemistry; Male; Middle Aged; Muscle Relaxants, Central; Muscle, Skeletal; Muscular Dystrophies; Nifedipine; Potassium Chloride; Sarcoplasmic Reticulum; Sodium-Potassium-Exchanging ATPase; Verapamil | 1996 |
The mechanism for hexachlorocyclohexane-induced cytotoxicity and changes in intracellular Ca2+ homeostasis in cultured cerebellar granule neurons is different for the gamma- and delta-isomers.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Chloride; Central Nervous System Depressants; Cerebellar Cortex; Convulsants; Dantrolene; Hexachlorocyclohexane; Homeostasis; Intracellular Fluid; Isomerism; Microscopy, Fluorescence; Neurons; Rats; Rats, Wistar; Second Messenger Systems; Structure-Activity Relationship; Verapamil | 1997 |
Shigella dysenteriae type 1 toxin induced lipid peroxidation in enterocytes isolated from rabbit ileum.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Bacterial Toxins; Calcimycin; Calcium Channel Blockers; Dantrolene; Dysentery, Bacillary; Enterotoxins; Enzyme Inhibitors; Ileum; In Vitro Techniques; Indomethacin; Ionophores; Lipid Peroxides; Male; Muscle Relaxants, Central; Rabbits; Reactive Oxygen Species; Shiga Toxins; Shigella dysenteriae; Tetradecanoylphorbol Acetate; Verapamil | 1998 |
Role of intracellular second messengers and reactive oxygen species in the pathophysiology of V. cholera O139 treated rabbit ileum.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Antioxidants; Calcimycin; Calcium; Calcium Channel Blockers; Cholera; Cyclic AMP; Dantrolene; Enzyme Activation; Ileum; Inositol Phosphates; Ionophores; Lipid Peroxidation; Protein Kinase C; Rabbits; Reactive Oxygen Species; Second Messenger Systems; Tetradecanoylphorbol Acetate; Verapamil; Water-Electrolyte Balance | 1998 |
Protection of ischemic rat heart by dantrolene, an antagonist of the sarcoplasmic reticulum calcium release channel.
Topics: Animals; Calcium; Dantrolene; Heart; Hemodynamics; Male; Myocardial Ischemia; Rats; Rats, Wistar; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Verapamil | 2000 |
Calcium uptake, release and ryanodine binding in melanosomes from retinal pigment epithelium.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Radioisotopes; Dantrolene; Inositol 1,4,5-Trisphosphate; Melanosomes; Nifedipine; Pigment Epithelium of Eye; Ranidae; Ryanodine; Thapsigargin; Tritium; Verapamil | 2000 |
Dantrolene sodium improves the force-frequency relationship and beta-adregenic responsiveness in failing human myocardium.
Topics: Adrenergic beta-Agonists; Calcium; Calcium Channel Blockers; Dantrolene; Female; Heart Failure; Heart Ventricles; Humans; In Vitro Techniques; Intracellular Fluid; Isometric Contraction; Isoproterenol; Male; Middle Aged; Muscle Relaxants, Central; Myocardial Contraction; Myocardium; Receptors, Adrenergic, beta; Verapamil | 1999 |
Reduction in intracellular calcium levels inhibits myoblast differentiation.
Topics: Actins; Animals; Blotting, Northern; Calcium; Calcium Channel Blockers; Cell Differentiation; Cells, Cultured; Dantrolene; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genes, Reporter; Luciferases; Mice; Microscopy, Fluorescence; Muscle, Skeletal; Muscles; Nifedipine; Promoter Regions, Genetic; Protein Isoforms; Thapsigargin; Time Factors; Verapamil | 2002 |
In vitro effects of dantrolene sodium and verapamil on noradrenaline-induced contractions of rabbit aorta and their interactions.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Dantrolene; Dose-Response Relationship, Drug; In Vitro Techniques; Muscle Contraction; Muscle Relaxants, Central; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Vasoconstrictor Agents; Verapamil | 2002 |
Nickel compound-induced DNA single-strand breaks in chromosomal and nuclear chromatin in human blood lymphocytes in vitro: role of oxidative stress and intracellular calcium.
Topics: Acetylcysteine; Analysis of Variance; Calcium; Catalase; Chromatin; Cytogenetic Analysis; Dantrolene; Deferoxamine; DNA Damage; Egtazic Acid; Humans; In Situ Nick-End Labeling; Lymphocytes; Microscopy, Electron; Mutagenicity Tests; Nickel; Oxidative Stress; Superoxide Dismutase; Thiourea; Verapamil | 2005 |
First phase of glucose-stimulated insulin secretion from MIN 6 cells does not always require extracellular calcium influx.
Topics: Animals; Calcium; Calcium Isotopes; Cell Line, Tumor; Cell Survival; Dantrolene; Diazoxide; Dose-Response Relationship, Drug; Extracellular Fluid; Glucose; Glyburide; Insulin; Insulin Antagonists; Insulin Secretion; Insulin-Secreting Cells; L-Lactate Dehydrogenase; Male; Mice; Potassium Channels; Sodium Channels; Tetrodotoxin; Tolbutamide; Verapamil | 2006 |
Gonadotropin-induced ovarian cancer cell migration and proliferation require extracellular signal-regulated kinase 1/2 activation regulated by calcium and protein kinase C{delta}.
Topics: Acetophenones; Benzopyrans; Calcium; Calcium Channels, L-Type; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dantrolene; Egtazic Acid; Female; Flavonoids; Follicle Stimulating Hormone; Humans; Indoles; Luteinizing Hormone; Maleimides; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Ovarian Neoplasms; Protein Kinase C-delta; RNA, Small Interfering; Signal Transduction; Verapamil | 2010 |
HOCl causes necrotic cell death in human monocyte derived macrophages through calcium dependent calpain activation.
Topics: Calcimycin; Calcium; Calcium Channel Blockers; Calcium Ionophores; Calpain; Caspase 3; Cyclosporine; Dantrolene; Enzyme Inhibitors; Flunarizine; Humans; Hypochlorous Acid; Lysosomes; Macrophages; Membrane Potential, Mitochondrial; Muscle Relaxants, Central; Necrosis; Nifedipine; Verapamil | 2012 |
Disruption of calcium homeostasis in cardiomyocytes underlies cardiac structural and functional changes in severe sepsis.
Topics: Actins; Animals; Animals, Newborn; Blotting, Western; Calcium; Calpain; Cecum; Cells, Cultured; Dantrolene; Dystrophin; Fluorescent Antibody Technique; Hemodynamics; Homeostasis; Intracellular Space; Ligation; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Punctures; Sarcomeres; Sepsis; Stroke Volume; Survival Analysis; Verapamil | 2013 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |