verapamil and cp 65,526

verapamil has been researched along with cp 65,526 in 12 studies

Research

Studies (12)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	7 (58.33)	18.2507
2000's	4 (33.33)	29.6817
2010's	1 (8.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Naito, M; Oh-hara, T; Sugawara, I; Tatsuta, T; Tsuruo, T	1
Gindin, E; Greenberger, LM; Horwitz, SB; Yang, CP	1
Chen, G; Dumontet, C; Durán, GE; Jaffrézou, JP; Lacayo, NJ; Sikic, BI; Steger, KA	1
Béliveau, R; Jetté, L; Murphy, GF	1
Airan, LE; Ambudkar, SV; Germann, UA; Gottesman, MM; Hrycyna, CA; Pastan, I	1
Dey, S; Gottesman, MM; Hafkemeyer, P; Pastan, I	1
Cheng, PW; Germann, UA; Gottesman, MM; Hrycyna, CA; Pastan, I; Ramachandra, M	1
Melera, PW; Song, J	2
Chattopadhyay, A; Dey, S; Fong, WF; Shen, XL; Wan, CK; Zhu, GY	1
Ambudkar, SV; Barnett, D; Bates, SE; Finley, EM; Fojo, T; Oldham, RK; Robey, RW; Shukla, S	1
Abel, B; Ambudkar, SV; Durell, SR; Jacobson, KA; Murakami, M; Tosh, DK; Vahedi, S	1

Trials

1 trial(s) available for verapamil and cp 65,526

Article	Year
Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)). Biochemical pharmacology, 2008, Mar-15, Volume: 75, Issue:6 Topics: Adenosine Triphosphatases; Alkaloids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Factors; Biological Transport; Cell Line; Cell Line, Tumor; Cyclosporins; Depsipeptides; Fluorescent Dyes; Fluorouracil; Humans; Insecta; Multidrug Resistance-Associated Proteins; Neoplasms; Paclitaxel; Prazosin; Quinolines; Rhodamine 123; Verapamil; Vinblastine	2008

Article

Year

Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)).

Biochemical pharmacology, 2008, Mar-15, Volume: 75, Issue:6

Topics: Adenosine Triphosphatases; Alkaloids; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Factors; Biological Transport; Cell Line; Cell Line, Tumor; Cyclosporins; Depsipeptides; Fluorescent Dyes; Fluorouracil; Humans; Insecta; Multidrug Resistance-Associated Proteins; Neoplasms; Paclitaxel; Prazosin; Quinolines; Rhodamine 123; Verapamil; Vinblastine

2008

Other Studies

11 other study(ies) available for verapamil and cp 65,526

Article	Year
Functional involvement of P-glycoprotein in blood-brain barrier. The Journal of biological chemistry, 1992, Oct-05, Volume: 267, Issue:28 Topics: Alkaline Phosphatase; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blood-Brain Barrier; Brain; Capillaries; Cells, Cultured; Drug Interactions; Endothelium, Vascular; gamma-Glutamyltransferase; Humans; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Microscopy, Immunoelectron; Prazosin; Tumor Cells, Cultured; Verapamil; Vincristine	1992
Photoaffinity probes for the alpha 1-adrenergic receptor and the calcium channel bind to a common domain in P-glycoprotein. The Journal of biological chemistry, 1990, Mar-15, Volume: 265, Issue:8 Topics: Affinity Labels; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Binding, Competitive; Calcium Channels; Cell Line; Cell Membrane; Chymotrypsin; Dihydropyridines; Drug Resistance; Macrophages; Membrane Glycoproteins; Mice; Peptide Mapping; Prazosin; Receptors, Adrenergic, alpha; Sequence Homology, Nucleic Acid; Verapamil	1990
Multidrug-resistant human sarcoma cells with a mutant P-glycoprotein, altered phenotype, and resistance to cyclosporins. The Journal of biological chemistry, 1997, Feb-28, Volume: 272, Issue:9 Topics: Affinity Labels; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blotting, Western; Cell Survival; Cyclosporins; Dihydropyridines; DNA Topoisomerases, Type II; Doxorubicin; Drug Resistance, Multiple; Humans; Neoplasm Proteins; Phenotype; Polymerase Chain Reaction; Prazosin; Rhodamine 123; Rhodamines; Sarcoma; Vault Ribonucleoprotein Particles; Verapamil	1997
Drug binding to P-glycoprotein is inhibited in normal tissues following SDZ-PSC 833 treatment. International journal of cancer, 1998, May-29, Volume: 76, Issue:5 Topics: Administration, Oral; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blotting, Western; Brain; Calcium Channel Blockers; Capillaries; Cyclosporine; Cyclosporins; Drug Interactions; Fluorescent Dyes; Injections, Subcutaneous; Iodine Radioisotopes; Kidney; Liver; Male; Microvilli; Photoaffinity Labels; Prazosin; Rats; Rats, Sprague-Dawley; Rhodamine 123; Rhodamines; Verapamil; Vinblastine	1998
Structural flexibility of the linker region of human P-glycoprotein permits ATP hydrolysis and drug transport. Biochemistry, 1998, Sep-29, Volume: 37, Issue:39 Topics: 3T3 Cells; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies, Monoclonal; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Base Sequence; Biological Transport; Cell Membrane; Drug Resistance, Multiple; Genetic Vectors; HeLa Cells; Humans; Hydrolysis; Iodine Radioisotopes; Mice; Molecular Sequence Data; Mutagenesis, Insertional; Osteosarcoma; Peptide Fragments; Prazosin; Protein Binding; Protein Conformation; Recombinant Proteins; Sequence Deletion; Tumor Cells, Cultured; Verapamil	1998
A single amino acid residue contributes to distinct mechanisms of inhibition of the human multidrug transporter by stereoisomers of the dopamine receptor antagonist flupentixol. Biochemistry, 1999, May-18, Volume: 38, Issue:20 Topics: Adenosine Triphosphate; Alanine; Amino Acid Substitution; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Biological Transport; Dopamine Antagonists; Flupenthixol; HeLa Cells; Humans; Hydrolysis; Iodine Radioisotopes; Mutagenesis, Site-Directed; Phenylalanine; Photoaffinity Labels; Prazosin; Receptors, Dopamine; Stereoisomerism; Substrate Specificity; Tumor Cells, Cultured; Verapamil	1999
Both ATP sites of human P-glycoprotein are essential but not symmetric. Biochemistry, 1999, Oct-19, Volume: 38, Issue:42 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Motifs; Amino Acid Substitution; Antibodies, Monoclonal; Asparagine; Aspartic Acid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding Sites; Biological Transport; Body Temperature; Cell Membrane; Consensus Sequence; Enzyme Activation; Freezing; HeLa Cells; Humans; Peptide Fragments; Phosphorus Radioisotopes; Photoaffinity Labels; Point Mutation; Prazosin; Protein Conformation; Recombinant Fusion Proteins; Vanadates; Verapamil	1999
Transmembrane domain (TM) 9 represents a novel site in P-glycoprotein that affects drug resistance and cooperates with TM6 to mediate [125I]iodoarylazidoprazosin labeling. Molecular pharmacology, 2001, Volume: 60, Issue:2 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Binding, Competitive; Cells, Cultured; Cricetinae; Cyclosporine; Drug Interactions; Drug Resistance; Drug Resistance, Multiple; Iodine Radioisotopes; Membrane Proteins; Mutagenesis, Site-Directed; Prazosin; Protein Structure, Tertiary; Transfection; Verapamil	2001
Further characterization of the sixth transmembrane domain of Pgp1 by site-directed mutagenesis. Cancer chemotherapy and pharmacology, 2001, Volume: 48, Issue:5 Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Cell Line; Cricetinae; Hydrophobic and Hydrophilic Interactions; Membrane Proteins; Mutagenesis, Site-Directed; Photoaffinity Labels; Prazosin; Structure-Activity Relationship; Transfection; Verapamil	2001
Gomisin A alters substrate interaction and reverses P-glycoprotein-mediated multidrug resistance in HepG2-DR cells. Biochemical pharmacology, 2006, Sep-28, Volume: 72, Issue:7 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Anticarcinogenic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azides; Blotting, Western; Cell Line, Tumor; Cell Survival; Cyclooctanes; Dioxoles; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Humans; Hydrolysis; Lignans; Prazosin; Reverse Transcriptase Polymerase Chain Reaction; Rhodamine 123; RNA, Messenger; Vanadates; Verapamil; Vinblastine	2006
Evidence for the Interaction of A Molecular pharmacology, 2019, Volume: 96, Issue:2 Topics: Adenosine A3 Receptor Agonists; ATP Binding Cassette Transporter, Subfamily B; Azides; Binding Sites; HeLa Cells; Humans; Models, Molecular; Molecular Docking Simulation; Paclitaxel; Prazosin; Structure-Activity Relationship; Verapamil	2019