verapamil has been researched along with cocaine in 45 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (28.89) | 18.7374 |
| 1990's | 13 (28.89) | 18.2507 |
| 2000's | 14 (31.11) | 29.6817 |
| 2010's | 5 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sen, S; Sinha, N | 1 |
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M | 1 |
| Keserü, GM | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Li, J; Rajamani, R; Reynolds, CH; Tounge, BA | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Cooper, RA; Dodean, RA; Hinrichs, DJ; Janowsky, A; Johnson, RA; Kelly, JX; Lane, KD; Riscoe, M; Smilkstein, MJ; Winter, R | 1 |
| Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Jia, L; Sun, H | 1 |
| Caron, G; Ermondi, G; Visentin, S | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bellman, K; Knegtel, RM; Settimo, L | 1 |
| Brouillette, WJ; Brown, GB; Zha, C | 1 |
| Kajitsuka, T | 1 |
| Paul, S; York, D | 1 |
| Bassett, AL; Kimura, S; Myerburg, RJ; Xi, H | 1 |
| Allen, RP; Hienz, RD; Kaminski, BJ; Sannerud, CA; Spear, DJ; Turkkan, JS | 1 |
| Castrucci, AM; Visconti, MA | 1 |
| Rubin, E; Stewart, G; Thomas, AP | 1 |
| Rogério, R; Takahashi, RN | 1 |
| Calogero, AE; Chrousos, GP; Gallucci, WT; Gold, PW; Kling, MA | 1 |
| Albertson, TE; Derlet, RW | 1 |
| Eikenburg, DC; Jandhyala, BS; Lokhandwala, MF; Peter, EJ; Steenberg, ML | 1 |
| Catanzaro, OL; Savino, EA | 1 |
| Diamond, S; Freitag, FG; Gandhi, S; Prager, J | 1 |
| Billman, GE; Hoskins, RS | 1 |
| Chaudhry, A; Vohra, MM | 1 |
| Kolassa, N; Pfleger, K; Volkmer, I | 1 |
| Bartsch, W; Knopf, KW | 1 |
| Galzin, AM; Langer, SZ | 1 |
| Antonio, A; Cabral, AM; Pires, JG; Yashuda, Y | 1 |
| Brewster, PS; Fraker, TD; Temesy-Armos, PN; Wilkerson, RD | 1 |
| Branch, CA; Knuepfer, MM | 1 |
| Goldberg, SR; Prada, J; Schindler, CW; Tella, SR | 1 |
| Alvarez, TA; Keller, PA; Konkol, RJ; Madden, JA | 1 |
| Altura, BM; Altura, BT; He, GQ; Zhang, A | 1 |
| Glamann, DB; Hillis, LD; Landau, C; Lange, RA; Negus, BH; Snyder, RW; Willard, JE | 1 |
| Tenenbein, M | 1 |
| Bechara, G; El-Bizri, NM; Khoury, HA; Sabra, R; Sharaf, LH | 1 |
| Mizutani, T | 1 |
| Aragon, CM; Baliño, P; Pastor, R | 1 |
2 review(s) available for verapamil and cocaine
| Article | Year |
|---|---|
Position statement: whole bowel irrigation. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Arsenic Poisoning; Child; Child, Preschool; Cocaine; Contraindications; Delayed-Action Preparations; Female; Fenfluramine; Humans; Infant; Intestines; Intubation, Gastrointestinal; Iron; Male; Poisoning; Therapeutic Irrigation; Verapamil; Zinc Sulfate | 1997 |
[Gut decontamination-5--whole bowel irrigation].
Topics: Animals; Arsenic Poisoning; Cocaine; Crime; Decontamination; Drug Packaging; Foreign Bodies; Humans; Intestines; Iron; Latex; Lead Poisoning; Therapeutic Irrigation; Verapamil; Zinc Sulfate | 2001 |
1 trial(s) available for verapamil and cocaine
| Article | Year |
|---|---|
Alleviation of cocaine-induced coronary vasoconstriction with intravenous verapamil.
Topics: Adult; Aged; Cocaine; Coronary Vessels; Female; Humans; Injections, Intravenous; Male; Middle Aged; Vasoconstriction; Verapamil | 1994 |
42 other study(ies) available for verapamil and cocaine
| Article | Year |
|---|---|
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2002 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
A two-state homology model of the hERG K+ channel: application to ligand binding.
Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Ligands; Models, Biological; Models, Molecular; Potassium Channels, Voltage-Gated; Protein Binding; Protein Conformation | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Design, synthesis, and evaluation of 10-N-substituted acridones as novel chemosensitizers in Plasmodium falciparum.
Topics: Acridones; Animals; Antimalarials; Cell Survival; Cells, Cultured; Drug Design; Drug Interactions; Drug Resistance, Multiple; Lymphocytes; Membrane Transport Proteins; Mice; Mice, Inbred C57BL; Molecular Structure; Mutation; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Structure-Activity Relationship | 2007 |
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation | 2014 |
A highly predictive 3D-QSAR model for binding to the voltage-gated sodium channel: design of potent new ligands.
Topics: Ligands; Models, Molecular; Quantitative Structure-Activity Relationship; Voltage-Gated Sodium Channels | 2014 |
Phasic and tonic contractions of rabbit intestinal muscle.
Topics: Animals; Atropine; Cocaine; Electric Stimulation; In Vitro Techniques; Intestine, Small; Muscle Contraction; Muscle Tonus; Nitroprusside; Rabbits; Tetrodotoxin; Verapamil | 1979 |
Cocaine abuse: an expanding healthcare problem for the 1990s.
Topics: Adult; Angina Pectoris; Angioplasty, Balloon, Coronary; Cardiac Catheterization; Cardiomyopathies; Cocaine; Coronary Vasospasm; Crack Cocaine; Diagnosis, Differential; Electrocardiography; Humans; Male; Nursing Assessment; Substance-Related Disorders; Verapamil | 1992 |
Early afterdepolarizations and triggered activity induced by cocaine. A possible mechanism of cocaine arrhythmogenesis.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Calcium Channels; Cats; Cells, Cultured; Cocaine; Female; Heart; Isoproterenol; Male; Myocardium; Potassium Channels; Verapamil | 1992 |
General activity in baboons measured with a computerized, lightweight piezoelectric motion sensor: effects of drugs.
Topics: Animals; Cocaine; Dextroamphetamine; Dronabinol; Hydrochlorothiazide; Male; Motor Activity; Papio; Psychology, Experimental; Verapamil | 1992 |
Ionic requirements for catecholamine aggregating actions on the teleost Poecilia reticulata melanophores.
Topics: Animals; Catecholamines; Cell Membrane; Cocaine; Dexamethasone; Dose-Response Relationship, Drug; Female; Ion Channels; Ions; Melanophores; Norepinephrine; Phenylephrine; Poecilia; Propranolol; Receptors, Adrenergic, alpha; Tetrodotoxin; Verapamil | 1990 |
Inhibition by cocaine of excitation-contraction coupling in isolated cardiomyocytes.
Topics: Animals; Calcium; Cell Separation; Cocaine; Dose-Response Relationship, Drug; Electric Conductivity; Heart; Lidocaine; Membrane Potentials; Myocardial Contraction; Myocardium; Nitrendipine; Potassium; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum; Sodium Channels; Sympathetic Nervous System; Tetrodotoxin; Verapamil | 1991 |
Some calcium channel antagonists have no effect on the open-field behavior of rats nor do they interact with cocaine.
Topics: Analysis of Variance; Animals; Behavior, Animal; Cocaine; Diltiazem; Drug Interactions; Male; Motor Activity; Nifedipine; Rats; Rats, Inbred Strains; Verapamil | 1990 |
Cocaine stimulates rat hypothalamic corticotropin-releasing hormone secretion in vitro.
Topics: Animals; Cocaine; Corticotropin-Releasing Hormone; Dexamethasone; gamma-Aminobutyric Acid; Hypothalamus; Male; Organ Culture Techniques; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Potentiation of cocaine toxicity with calcium channel blockers.
Topics: Animals; Cocaine; Diltiazem; Drug Synergism; Injections, Intraperitoneal; Male; Nifedipine; Rats; Rats, Inbred Strains; Seizures; Verapamil | 1989 |
Influence of felodipine and verapamil on the sympathetic transmitter release and on the pre- and post-junctional effects of exogenous noradrenaline in the perfused rat kidney.
Topics: Animals; Antihypertensive Agents; Cocaine; Electric Stimulation; Felodipine; In Vitro Techniques; Kidney; Male; Neuromuscular Junction; Neurotransmitter Agents; Nifedipine; Norepinephrine; Rats; Rats, Inbred Strains; Sympathetic Nervous System; Verapamil | 1985 |
Effects of tityustoxin on the rat isolated tail artery.
Topics: Animals; Arteries; Blood Pressure; Catecholamines; Cocaine; Dose-Response Relationship, Drug; Male; Neurotoxins; Phentolamine; Rats; Reserpine; Scorpion Venoms; Tail; Tetrodotoxin; Vasoconstriction; Verapamil | 1985 |
Treatment of intractable cluster.
Topics: Cluster Headache; Cocaine; Female; Histamine Antagonists; Humans; Lithium; Lithium Carbonate; Male; Vascular Headaches; Verapamil | 1986 |
Cocaine-induced ventricular fibrillation: protection afforded by the calcium antagonist verapamil.
Topics: Animals; Arrhythmias, Cardiac; Blood Flow Velocity; Blood Pressure; Cocaine; Dogs; Heart Rate; Ischemia; Physical Exertion; Tape Recording; Ventricular Fibrillation; Verapamil | 1988 |
Mechanism and metabolic disposition of verapamil-evoked overflow of radioactivity from isolated atria preloaded with [3H]norepinephrine.
Topics: Animals; Calcium; Cocaine; Heart Atria; In Vitro Techniques; Male; Myocardium; Norepinephrine; Pargyline; Rats; Rats, Inbred Strains; Reserpine; Tetrodotoxin; Verapamil | 1985 |
[Inhibition of adenosine uptake and stimulation of its effect on isolated hearts of warm-blooded animals by coronary active substances].
Topics: Alkaloids; Allopurinol; Animals; Carbon Isotopes; Cocaine; Depression, Chemical; Dipyridamole; Drug Synergism; Ethylenediamines; Guinea Pigs; Heart Rate; In Vitro Techniques; Myocardium; Nitroglycerin; Nucleosides; Ouabain; Papaverine; Prenylamine; Probenecid; Pyridines; Reserpine; Stimulation, Chemical; Theophylline; Triamterene; Vasodilator Agents; Verapamil | 1969 |
[Modified method for the testing of surface anesthesia on the rabbit cornea, using cocaine, procaine, propranolol, alprenolol, INPEA and verapamil].
Topics: Amino Alcohols; Anesthesia, Local; Anesthetics, Local; Animals; Anti-Arrhythmia Agents; Cocaine; Cornea; Nitriles; Nitrobenzenes; Procaine; Propranolol; Rabbits; Sympatholytics; Vasodilator Agents; Verapamil | 1970 |
Presynaptic alpha 2-adrenoceptor antagonism by verapamil but not by diltiazem in rabbit hypothalamic slices.
Topics: Adrenergic alpha-Antagonists; Animals; Benzazepines; Calcium Channel Blockers; Clonidine; Cocaine; Diltiazem; Epinephrine; Hypothalamus; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Receptors, Adrenergic; Receptors, Adrenergic, alpha; Verapamil | 1983 |
Dissociation of calcium- and barium-induced contractions of the rat duodenum smooth muscle.
Topics: Animals; Barium; Calcium; Cocaine; Duodenum; Epinephrine; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Potassium; Rats; Time Factors; Verapamil | 1983 |
Interaction of propranolol, verapamil, and nifedipine on the myocardial depressant effect of cocaine.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Cocaine; Dogs; Drug Interactions; Echocardiography; Electrocardiography; Female; Heart Rate; Male; Nifedipine; Propranolol; Stroke Volume; Ventricular Function, Left; Verapamil | 1995 |
Calcium channel antagonists reduce the cocaine-induced decrease in cardiac output in a subset of rats.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cardiac Output; Cocaine; Heart Rate; Male; Nifedipine; Rats; Rats, Sprague-Dawley; Stroke Volume; Vascular Resistance; Verapamil | 1993 |
Calcium channel blockers antagonize some of cocaine's cardiovascular effects, but fail to alter cocaine's behavioral effects.
Topics: Animals; Blood Pressure; Calcium Channel Blockers; Cocaine; Conditioning, Psychological; Diltiazem; Heart Rate; Male; Nimodipine; Saimiri; Self Administration; Verapamil | 1995 |
Cocaine and benzoylecgonine constrict cerebral arteries by different mechanisms.
Topics: Animals; Calcium; Cats; Cerebral Arteries; Cocaine; Female; Male; Norepinephrine; Oxidopamine; Prazosin; Ryanodine; Sympathectomy, Chemical; Vasoconstriction; Vasomotor System; Verapamil; Yohimbine | 1995 |
Cocaine-induced cerebrovasospasm and its possible mechanism of action.
Topics: Animals; Biological Transport; Brain; Calcium; Cells, Cultured; Cocaine; Cyclooxygenase Inhibitors; Dogs; Dopamine; Dopamine Antagonists; Eicosanoids; Female; Haloperidol; Indomethacin; Ischemic Attack, Transient; Male; Muscle Contraction; Sheep; Swine; Verapamil | 1994 |
Post-junctional mechanisms involved in the potentiation of cardiac adrenergic responses by cocaine.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Blood Pressure; Cats; Chlorisondamine; Cocaine; Diastole; Dose-Response Relationship, Drug; Excitatory Postsynaptic Potentials; Female; Heart; Isoproterenol; Long-Term Potentiation; Male; Neuromuscular Junction; Norepinephrine; Phenoxybenzamine; Systole; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 2000 |
Participation of L-type calcium channels in ethanol-induced behavioral stimulation and motor incoordination: effects of diltiazem and verapamil.
Topics: Analysis of Variance; Animals; Ataxia; Behavior, Animal; Caffeine; Calcium Channel Blockers; Calcium Channels, L-Type; Central Nervous System Stimulants; Cocaine; Diltiazem; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Motor Activity; Rotarod Performance Test; Verapamil | 2010 |