verapamil and clomipramine

verapamil has been researched along with clomipramine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19902 (7.14)18.7374
1990's4 (14.29)18.2507
2000's11 (39.29)29.6817
2010's11 (39.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Abraham, MH; Acree, WE; Ibrahim, A1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Lombardo, F; Obach, RS; Waters, NJ1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U1
Fijorek, K; Glinka, A; Mendyk, A; Polak, S; Wiśniowska, B1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Flanigan, P; Freshney, RI; Hamilton, TG; Kaye, SB; Merry, S1
Iida, H; Sakurai, Y; Tsukagoshi, S; Tsuruo, T1
Hayashi, T; Kagaya, A; Motohashi, N; Nagaoka, I; Okamoto, Y; Yamaji, T; Yamawaki, S1
Hayashi, T; Kagaya, A; Motohashi, N; Okamoto, Y; Yamaji, T; Yamawaki, S1
Kagaya, A; Uchitomi, Y; Yamaji, T; Yamawaki, S; Yokota, N1
Amaral, L; Farkas, S; Gunics, G; Molnár, J; Motohashi, N1
Nath, C; Srivastava, SK1
Feroli, S; Heyden, A; Kerwin, RW; Lovestone, S; Makoff, A; Miller, AH; Pariante, CM1
Dong, QX; Gao, JM; He, JH; Huang, CJ; Li, CQ; Xu, YQ; Xuan, YX; Yu, HP; Zhu, JJ1
Hosseiny Davarani, SS; Memarian, E; Moazami, HR; Nojavan, S1

Reviews

1 review(s) available for verapamil and clomipramine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

27 other study(ies) available for verapamil and clomipramine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
    European journal of medicinal chemistry, 2008, Volume: 43, Issue:3

    Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization

2008
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1

    Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests

2012
Predictive model for L-type channel inhibition: multichannel block in QT prolongation risk assessment.
    Journal of applied toxicology : JAT, 2012, Volume: 32, Issue:10

    Topics: Artificial Intelligence; Calcium Channel Blockers; Calcium Channels, L-Type; Cell Line; Computational Biology; Computer Simulation; Drugs, Investigational; Ether-A-Go-Go Potassium Channels; Expert Systems; Heart Rate; Humans; Models, Biological; Myocytes, Cardiac; NAV1.5 Voltage-Gated Sodium Channel; Potassium Channel Blockers; Quantitative Structure-Activity Relationship; Risk Assessment; Shaker Superfamily of Potassium Channels; Torsades de Pointes; Voltage-Gated Sodium Channel Blockers

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Circumvention of pleiotropic drug resistance in subcutaneous tumours in vivo with verapamil and clomipramine.
    European journal of cancer (Oxford, England : 1990), 1991, Volume: 27, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Clomipramine; Dactinomycin; Doxorubicin; Drug Resistance; Etoposide; Female; Male; Mice; Mice, Inbred AKR; Osteosarcoma; Verapamil; Vincristine

1991
Increased accumulation of vincristine and adriamycin in drug-resistant P388 tumor cells following incubation with calcium antagonists and calmodulin inhibitors.
    Cancer research, 1982, Volume: 42, Issue:11

    Topics: Animals; Calcium Channel Blockers; Calcium-Binding Proteins; Calmodulin; Clomipramine; Doxorubicin; Drug Resistance; Kinetics; Leukemia P388; Leukemia, Experimental; Mice; Prenylamine; Quinoxalines; Trifluoperazine; Verapamil; Vincristine

1982
Intracellular calcium concentration in C6BU-1 rat glioma cells: a single cell study using fluorescence microscopy/video imaging system.
    The Japanese journal of psychiatry and neurology, 1993, Volume: 47, Issue:2

    Topics: Animals; Antidepressive Agents; Calcium; Cell Line; Clomipramine; Glioma; Microscopy, Fluorescence; Rats; Receptors, Serotonin; Serotonin; Tumor Cells, Cultured; Verapamil; Video Recording

1993
Effects of clomipramine and verapamil on 5-HT-induced intracellular calcium changes in individual C6 rat glioma cells.
    Neuropsychobiology, 1996, Volume: 33, Issue:2

    Topics: Animals; Calcium; Clomipramine; Dose-Response Relationship, Drug; Glioma; Rats; Serotonin; Time Factors; Verapamil

1996
Chronic treatment with antidepressants, verapamil, or lithium inhibits the serotonin-induced intracellular calcium response in individual C6 rat glioma cells.
    Life sciences, 1997, Volume: 60, Issue:11

    Topics: Animals; Antidepressive Agents; Calcium; Calcium Channel Blockers; Citalopram; Clomipramine; Drug Interactions; Glioma; Intracellular Fluid; Lithium Chloride; Rats; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Antagonists; Tumor Cells, Cultured; Verapamil

1997
Interaction between antibiotics and non-conventional antibiotics on bacteria.
    International journal of antimicrobial agents, 2000, Volume: 14, Issue:3

    Topics: Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Antipruritics; Bacteria; Calcium Channel Blockers; Clomipramine; Drug Combinations; Drug Interactions; Drug Resistance, Microbial; Erythromycin; Escherichia coli; Gentamicins; Humans; Methylene Blue; Promethazine; Pseudomonas aeruginosa; Selective Serotonin Reuptake Inhibitors; Staphylococcus epidermidis; Tetracycline; Verapamil

2000
The differential effects of calcium channel blockers in the behavioural despair test in mice.
    Pharmacological research, 2000, Volume: 42, Issue:4

    Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Clomipramine; Clonidine; Cyproheptadine; Depression; Desipramine; Diltiazem; Drug Interactions; Female; Male; Mianserin; Mice; Motor Activity; Nifedipine; Tranylcypromine; Verapamil

2000
Antidepressants enhance glucocorticoid receptor function in vitro by modulating the membrane steroid transporters.
    British journal of pharmacology, 2001, Volume: 134, Issue:6

    Topics: Animals; Antidepressive Agents; Calcium Channel Blockers; Cell Line; Chloramphenicol O-Acetyltransferase; Clomipramine; Corticosterone; Dexamethasone; Glucocorticoids; Hydrocortisone; In Vitro Techniques; Paroxetine; Receptors, Glucocorticoid; Selective Serotonin Reuptake Inhibitors; Transcription, Genetic; Verapamil

2001
Human cardiotoxic drugs delivered by soaking and microinjection induce cardiovascular toxicity in zebrafish.
    Journal of applied toxicology : JAT, 2014, Volume: 34, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Aspirin; Cardiotoxins; Clomipramine; Cyclophosphamide; Disease Models, Animal; Edema; Gentamicins; Heart Diseases; Heart Rate; Heart Ventricles; Larva; Microinjections; Nimodipine; Pericardium; Quinidine; Terfenadine; Tetracycline; Toxicity Tests; Verapamil; Yolk Sac; Zebrafish

2014
Electromembrane extraction through a virtually rotating supported liquid membrane.
    Electrophoresis, 2016, Volume: 37, Issue:2

    Topics: Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Chemical Fractionation; Clomipramine; Electrochemical Techniques; Electrodes; Equipment Design; Humans; Limit of Detection; Membranes, Artificial; Rotation; Trimipramine; Urinalysis; Verapamil; Wastewater; Water Pollutants, Chemical; Water Purification

2016