verapamil and clofazimine

verapamil has been researched along with clofazimine in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (7.69)18.2507
2000's4 (30.77)29.6817
2010's7 (53.85)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Casciano, CN; Clement, RP; Johnson, WW; Wang, EJ2
Cianchetta, G; Cruciani, G; Fravolini, A; Giesing, D; Singleton, RW; Vaz, RJ; Wildgoose, M; Zhang, M1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Balcazar, DE; Bellera, CL; Bruno-Blanch, LE; Carrillo, C; Casassa, AF; Gálvez, J; Gavernet, L; Labriola, CA; Palestro, PH; Romano, PS; Talevi, A; Vanrell, MC1
Anderson, R; Jooné, G; Van Rensburg, CE1
Andries, K; Coeck, N; de Jong, BC; Gevers, T; Koul, A; Lounis, N; Thys, K; Villellas, C; Vranckx, L1
Almeida, DV; Barnes-Boyle, K; Li, SY; Lu, Y; Nuermberger, E; Peloquin, CA; Tasneen, R; Xu, J1
Chen, C; Dartois, V; Dick, T; Gardete, S; Jansen, RS; Rhee, KY; Shetty, A1
Ammerman, NC; Bax, HI; de Steenwinkel, JEM; de Vogel, CP; Mudde, SE; Schildkraut, JA; van Ingen, J1

Other Studies

13 other study(ies) available for verapamil and clofazimine

ArticleYear
Active transport of fluorescent P-glycoprotein substrates: evaluation as markers and interaction with inhibitors.
    Biochemical and biophysical research communications, 2001, Nov-30, Volume: 289, Issue:2

    Topics: 3T3 Cells; Adrenergic Uptake Inhibitors; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport, Active; Cell Line; Cell Separation; Cell Survival; Flow Cytometry; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Mice; Protein Binding; Reserpine; Spectrometry, Fluorescence; Substrate Specificity; Time Factors

2001
Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites.
    Pharmaceutical research, 2003, Volume: 20, Issue:4

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Binding Sites; Biological Transport, Active; Biomarkers; Cells, Cultured; Drug Interactions; Fluorescent Dyes; Humans

2003
A pharmacophore hypothesis for P-glycoprotein substrate recognition using GRIND-based 3D-QSAR.
    Journal of medicinal chemistry, 2005, Apr-21, Volume: 48, Issue:8

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Fluoresceins; Fluorescent Dyes; Humans; Models, Molecular; Multivariate Analysis; Permeability; Quantitative Structure-Activity Relationship

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Computer-guided drug repurposing: identification of trypanocidal activity of clofazimine, benidipine and saquinavir.
    European journal of medicinal chemistry, 2015, Mar-26, Volume: 93

    Topics: Animals; Clofazimine; Cysteine Endopeptidases; Dihydropyridines; Drug Repositioning; Female; Male; Mice; Molecular Docking Simulation; Protein Conformation; Protozoan Proteins; Saquinavir; Trypanocidal Agents; Trypanosoma cruzi

2015
Alpha-tocopherol antagonizes the multidrug-resistance-reversal activity of cyclosporin A, verapamil, GF120918, clofazimine and B669.
    Cancer letters, 1998, May-15, Volume: 127, Issue:1-2

    Topics: Acridines; Cell Death; Clofazimine; Cyclosporine; Drug Resistance, Multiple; Humans; Isoquinolines; Lung Neoplasms; Tetrahydroisoquinolines; Tumor Cells, Cultured; Verapamil; Vinblastine; Vitamin E

1998
Acquired resistance of Mycobacterium tuberculosis to bedaquiline.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Animals; Antitubercular Agents; Bacterial Proteins; Base Sequence; Clofazimine; Diarylquinolines; Drug Resistance, Bacterial; Genes, Bacterial; Genetic Fitness; Humans; Mice; Microbial Sensitivity Tests; Models, Biological; Molecular Sequence Data; Mutation; Mycobacterium tuberculosis; Reserpine; Tuberculosis; Up-Regulation; Verapamil

2014
Verapamil Increases the Bioavailability and Efficacy of Bedaquiline but Not Clofazimine in a Murine Model of Tuberculosis.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:1

    Topics: Animals; Antitubercular Agents; Biological Availability; Calcium Channel Blockers; Clofazimine; Colony Count, Microbial; Diarylquinolines; Drug Resistance, Bacterial; Female; Lung; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Tuberculosis; Verapamil

2018
Verapamil Targets Membrane Energetics in Mycobacterium tuberculosis.
    Antimicrobial agents and chemotherapy, 2018, Volume: 62, Issue:5

    Topics: Animals; Antitubercular Agents; Calcium Channel Blockers; Cell Membrane; Clofazimine; Diarylquinolines; Drug Synergism; Female; Humans; Mice; Microbial Sensitivity Tests; Mycobacterium tuberculosis; Verapamil

2018
Unraveling antibiotic resistance mechanisms in Mycobacterium abscessus: the potential role of efflux pumps.
    Journal of global antimicrobial resistance, 2022, Volume: 31

    Topics: Amikacin; Anti-Bacterial Agents; Cefoxitin; Clarithromycin; Clofazimine; Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Mycobacterium abscessus; Thioridazine; Tigecycline; Verapamil

2022