verapamil has been researched along with calcein am in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (17.24) | 18.2507 |
| 2000's | 14 (48.28) | 29.6817 |
| 2010's | 9 (31.03) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| Loor, F; Tiberghien, F | 1 |
| Bakos, E; Klein, I; Müller, M; Sarkadi, B; Szabó, K; Váradi, A; Welker, E | 1 |
| Müller, M; Roninson, I; Sarkadi, B; Szabó, K; Váradi, A; Welker, E | 1 |
| Antal, F; Jakab, K; Sarkadi, B; Szakács, G | 1 |
| Dagger, F; Essodaïgui, M; Frézard, F; Garnier-Suillerot, A; Moreira, ES | 1 |
| Anagnostopoulos, N; Androutsos, G; Galanopoulos, A; Kalmantis, T; Meletis, J; Paterakis, G; Rombos, Y; Sagriotis, A; Symeonidis, A; Tiniakou, M; Tsimberidou, AM; Yataganas, X; Zoumbos, N | 1 |
| Pajeva, IK; Wiese, M | 1 |
| Bartlett, MC; Clarke, DM; Loo, TW | 2 |
| Bacchelli, B; Boraldi, F; Croce, MA; Garcia Fernandez, MI; Gheduzzi, D; Pasquali Ronchetti, I; Quaglino, D; Tiozzo, R | 1 |
| Elliott, JI; Higgins, CF; Raguz, S | 1 |
| Frigieri, A; Huet, H; Huynh-Delerme, C; Kolf-Clauw, M; Noël, L | 1 |
| Angelini, A; Baccante, G; Ciofani, G; Cuccurullo, F; Di Febbo, C; Di Ilio, C; Di Nisio, M; Porreca, E | 1 |
| Cole, B; Epel, D; Hamdoun, A; Thurber, RV | 1 |
| Bubik, M; Fricker, G; Mahringer, A; Ott, M | 1 |
| Baubichon-Cortay, H; Chang, XB; Di Pietro, A; Perrotton, T; Trompier, D | 1 |
| Chen, YH; Lan, ZJ; Ning, BT; Qian, BQ; Shen, HQ; Tang, YM | 1 |
| Gassner, B; Gekle, M; Kelleher, DK; Thews, O | 1 |
| Brennan, NK; Detty, MR; Moore, TM; Raub, TJ; Sawada, GA; Tombline, G; William Higgins, J | 1 |
| Choy, E; Duan, Z; Hornicek, F; Mankin, H; Schwab, J; Susa, M; Yang, C | 1 |
| Chattipakorn, N; Chattipakorn, S; Fucharoen, S; Kumfu, S; Settakorn, J; Srichairatanakool, S | 1 |
| Bertelli, E; Dragoni, S; Franco, G; Frosini, M; Gori, M; Possidente, M; Teodori, E; Valoti, M | 1 |
| Kuo, YC; Lu, CH | 1 |
| Gabriel, S; Heinemann, U; Kovács, R; Raue, C | 1 |
| Baba, K; Hamahata, Y; Iwanaga, K; Kakemi, M; Miyazaki, M; Shibano, M; Taniguchi, M; Yoneda, S | 1 |
| Jakob, I; Molinas, A; Sicard, G | 1 |
| Chiou, MH; Hsieh, YW; Huang, CL; Hung, CC; Lane, HY; Teng, YN | 1 |
| Abele, D; Bickmeyer, U; Dringen, R; Petters, C; Rivera-Ingraham, G; Tietje, K | 1 |
| Hung, CC; Lan, YH; Lin, KI; Lin, YC; Teng, YN; Thang, TD | 1 |
1 review(s) available for verapamil and calcein am
| Article | Year |
|---|---|
Diagnostics of multidrug resistance in cancer.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Diagnosis; Drug Resistance, Neoplasm; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Humans; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Neoplasms; Neoplastic Stem Cells; Prostaglandins A; RNA, Messenger; RNA, Neoplasm; Verapamil | 1998 |
28 other study(ies) available for verapamil and calcein am
| Article | Year |
|---|---|
Ranking of P-glycoprotein substrates and inhibitors by a calcein-AM fluorometry screening assay.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Drug Screening Assays, Antitumor; Fluoresceins; Fluorescent Dyes; Humans; Mice; Peptides, Cyclic; Tumor Cells, Cultured; Verapamil; Vinblastine | 1996 |
Characterization of the human multidrug resistance protein containing mutations in the ATP-binding cassette signature region.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Binding Sites; Calcium Channel Blockers; Consensus Sequence; DNA, Complementary; Drug Resistance, Multiple; Fluoresceins; Genetic Vectors; Humans; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Nucleopolyhedroviruses; Recombinant Fusion Proteins; Rhodamine 123; Rhodamines; Spodoptera; Structure-Activity Relationship; Valinomycin; Verapamil | 1997 |
Drug-stimulated nucleotide trapping in the human multidrug transporter MDR1. Cooperation of the nucleotide binding domains.
Topics: Adenine Nucleotides; Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cyclosporine; Enzyme Inhibitors; Ethylmaleimide; Fluoresceins; Fluorouracil; Humans; Protein Binding; Recombinant Proteins; Verapamil | 1998 |
Energy-dependent efflux from Leishmania promastigotes of substrates of the mammalian multidrug resistance pumps.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; Biological Transport; Cyclic P-Oxides; Doxorubicin; Drug Resistance, Multiple; Energy Metabolism; Fluoresceins; Fluorescent Dyes; Leishmania; Nicotinic Acids; Phenothiazines; Tumor Cells, Cultured; Verapamil | 1999 |
Evaluation of the clinical relevance of the expression and function of P-glycoprotein, multidrug resistance protein and lung resistance protein in patients with primary acute myelogenous leukemia.
Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Bone Marrow Transplantation; Calcium Channel Blockers; Carbocyanines; Combined Modality Therapy; Cytarabine; Daunorubicin; Disease-Free Survival; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Fluoresceins; Fluorescent Dyes; Genistein; Humans; Idarubicin; Immunophenotyping; Leukemia, Myeloid; Male; Middle Aged; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Probenecid; Prognosis; Prospective Studies; Rhodamine 123; Survival Analysis; Tumor Cells, Cultured; Vault Ribonucleoprotein Particles; Verapamil | 2002 |
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis).
Topics: Adenosine Triphosphatases; Algorithms; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Binding, Competitive; Caco-2 Cells; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoresceins; Humans; Ligands; Models, Molecular; Molecular Structure; Quantitative Structure-Activity Relationship; Radioligand Assay; Rhodamine 123; Stereoisomerism; Verapamil; Vinblastine | 2002 |
Methanethiosulfonate derivatives of rhodamine and verapamil activate human P-glycoprotein at different sites.
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzimidazoles; Binding Sites; Biological Transport; Calcium Channel Blockers; Cell Line; Colchicine; Cysteine; Disulfides; DNA, Complementary; Dose-Response Relationship, Drug; Fluoresceins; Fluorescent Dyes; Histidine; Humans; Mesylates; Models, Biological; Models, Chemical; Mutation; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Rhodamines; Verapamil | 2003 |
Multidrug resistance protein-6 (MRP6) in human dermal fibroblasts. Comparison between cells from normal subjects and from Pseudoxanthoma elasticum patients.
Topics: Adult; Benzbromarone; Cell Count; Cell Division; Chlorambucil; Female; Fibroblasts; Fluoresceins; Fluorescent Dyes; Humans; Indomethacin; Lysosomes; Male; Membrane Transport Proteins; Microscopy, Fluorescence; Middle Aged; Multidrug Resistance-Associated Proteins; Propionates; Pseudoxanthoma Elasticum; Quinolines; Skin; Verapamil; Vinblastine | 2003 |
Multidrug transporter activity in lymphocytes.
Topics: Adrenergic alpha-Antagonists; Aniline Compounds; Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; B-Lymphocytes; Calcium Channel Blockers; Fluoresceins; Fluorescent Dyes; Lymphocytes; Mice; Mice, Knockout; Mitoxantrone; Multidrug Resistance-Associated Proteins; Paclitaxel; Prazosin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; T-Lymphocytes; Verapamil; Xanthenes | 2004 |
Increased functional expression of P-glycoprotein in Caco-2 TC7 cells exposed long-term to cadmium.
Topics: ATP Binding Cassette Transporter, Subfamily B; Benzimidazoles; Blotting, Western; Caco-2 Cells; Cadmium Poisoning; Calcium Channel Blockers; Cell Survival; DNA; Drug Resistance, Multiple; Electrophoresis, Agar Gel; Fluoresceins; Fluorescent Dyes; Humans; L-Lactate Dehydrogenase; Neutral Red; Tetrazolium Salts; Thiazoles; Verapamil | 2005 |
Inhibition of P-glycoprotein-mediated multidrug resistance by unfractionated heparin: a new potential chemosensitizer for cancer therapy.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Breast Neoplasms; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Fluoresceins; Heparin; Humans; Verapamil | 2005 |
Transmembrane segment 1 of human P-glycoprotein contributes to the drug-binding pocket.
Topics: Adenosine Triphosphatases; Amino Acid Sequence; Amino Acid Substitution; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Cell Line; Colchicine; Cricetinae; Cyclosporine; Demecolcine; Disulfides; Dithiothreitol; Fluoresceins; Flupenthixol; Humans; Mesylates; Point Mutation; Protein Structure, Tertiary; Verapamil; Vinblastine | 2006 |
The sea urchin embryo as a model for studying efflux transporters: roles and energy cost.
Topics: Animals; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Division; Cyclosporins; Cytotoxins; Embryo, Nonmammalian; Energy Metabolism; Etoposide; Fluoresceins; Membrane Transport Proteins; Models, Animal; Propionates; Quinolines; Sea Urchins; Verapamil; Vinblastine | 2006 |
Rapid assessment of p-glycoprotein-drug interactions at the blood-brain barrier.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Blotting, Western; Cells, Cultured; Drug Interactions; Endothelium, Vascular; Fluoresceins; Fluorescent Dyes; Pharmaceutical Preparations; Swine; Verapamil | 2006 |
(R)- and (S)-verapamil differentially modulate the multidrug-resistant protein MRP1.
Topics: Adenosine Triphosphatases; Animals; Cell Line; Cell Proliferation; Cell Survival; Cricetinae; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Fluoresceins; Fluorescent Dyes; Formazans; Glutathione; Inhibitory Concentration 50; Kidney; Leukotriene C4; Multidrug Resistance-Associated Proteins; Protein Conformation; Sodium Iodide; Spectrometry, Fluorescence; Stereoisomerism; Tetrazolium Salts; Transfection; Tryptophan; Verapamil | 2007 |
[Evaluation of the P-gp pump function on leukemic cell membrane and proper application of its reversal agents with Calcein-AM and flow cytometry].
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Child; Drug Resistance, Multiple; Flow Cytometry; Fluoresceins; Humans; K562 Cells; Tumor Cells, Cultured; Verapamil; Vincristine | 2007 |
Activity of drug efflux transporters in tumor cells under hypoxic conditions.
Topics: Acidosis; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Carcinoma; Cell Hypoxia; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Fluoresceins; Fluorescent Dyes; Isotonic Solutions; Male; Multidrug Resistance-Associated Proteins; Prostatic Neoplasms; Rats; Rhodamine 123; Ringer's Solution; Time Factors; Verapamil | 2008 |
Chalcogenopyrylium dyes as inhibitors/modulators of P-glycoprotein in multidrug-resistant cells.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Calcium Channel Blockers; Cell Membrane Permeability; Cell Polarity; Cells, Cultured; Chalcogens; Dogs; Drug Resistance, Multiple; Fluoresceins; Fluorescent Dyes; Humans; Inhibitory Concentration 50; Verapamil | 2008 |
Multidrug resistance reversal agent, NSC77037, identified with a cell-based screening assay.
Topics: Adenosine Triphosphatases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzylisoquinolines; Cell Line, Tumor; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Fluoresceins; Humans; Paclitaxel; Substrate Specificity; Time Factors; Verapamil | 2010 |
T-type calcium channel as a portal of iron uptake into cardiomyocytes of beta-thalassemic mice.
Topics: Animals; beta-Thalassemia; Calcium Channels, T-Type; Cell Survival; Cells, Cultured; Deferoxamine; Disease Models, Animal; Fluoresceins; Heterozygote; Immunohistochemistry; Iron; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Verapamil | 2011 |
Rat intestinal precision-cut slices as an in vitro model to study xenobiotic interaction with transporters.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Fluoresceins; Fluorescent Dyes; Glyburide; Indomethacin; Intestine, Small; Male; Microtomy; Multidrug Resistance-Associated Proteins; Rats; Rats, Wistar; Verapamil; Xenobiotics | 2011 |
Regulation of endocytosis into human brain-microvascular endothelial cells by inhibition of efflux proteins.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Cell Death; Cell Survival; Endocytosis; Endothelial Cells; Fluoresceins; Humans; Microvessels; Multidrug Resistance-Associated Proteins; Probenecid; Tight Junctions; Verapamil | 2011 |
Functional test of multidrug transporter activity in hippocampal-neocortical brain slices from epileptic patients.
Topics: Adjuvants, Pharmaceutic; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Epilepsy; Fluoresceins; Gene Expression Regulation; Hippocampus; Humans; In Vitro Techniques; Multidrug Resistance-Associated Proteins; Neocortex; Nerve Tissue Proteins; Neurons; Probenecid; Verapamil | 2011 |
Inhibitory effects of furanocoumarin derivatives in Kampo extract medicines on P-glycoprotein at the blood-brain barrier.
Topics: Animals; Apiaceae; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Blood-Brain Barrier; Caco-2 Cells; Cattle; Citrus paradisi; Coumarins; Endothelial Cells; Enzyme Inhibitors; Fluoresceins; Furans; Furocoumarins; Herb-Drug Interactions; Humans; Intestinal Absorption; Male; Medicine, Kampo; Permeability; Plant Extracts; Rats; Rats, Wistar; Rutaceae; Verapamil | 2011 |
Functional evidence of multidrug resistance transporters (MDR) in rodent olfactory epithelium.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Sub-Family B Member 4; Biological Transport; Cyclosporine; Female; Fluoresceins; Gene Expression; Male; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Multidrug Resistance-Associated Proteins; Olfactory Mucosa; Olfactory Receptor Neurons; Probenecid; Propionates; Quinolines; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Verapamil | 2012 |
Functional impact of ABCB1 variants on interactions between P-glycoprotein and methadone.
Topics: Analysis of Variance; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Fluoresceins; Genetic Variation; HEK293 Cells; Humans; Immunoblotting; Inhibitory Concentration 50; Kinetics; Methadone; Mutagenesis, Site-Directed; Real-Time Polymerase Chain Reaction; Rhodamine 123; Verapamil | 2013 |
Reporter dyes demonstrate functional expression of multidrug resistance proteins in the marine flatworm Macrostomum lignano: the sponge-derived dye Ageladine A is not a substrate of these transporters.
Topics: Aniline Compounds; Animals; Astrocytes; Biological Transport; Brain; Cells, Cultured; Coloring Agents; Fluoresceins; Fluorescent Dyes; Fura-2; Glutathione; Multidrug Resistance-Associated Proteins; Platyhelminths; Probenecid; Pyrroles; Rats; Rats, Wistar; Rhodamines; Verapamil; Xanthenes | 2013 |
A novel flavonoid from Fissistigma cupreonitens, 5‑hydroxy‑7,8‑dimethoxyflavanone, competitively inhibited the efflux function of human P-glycoprotein and reversed cancer multi-drug resistance.
Topics: Annonaceae; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Cycle; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Flavonoids; Fluoresceins; Humans; Molecular Docking Simulation; Phytochemicals; Rhodamine 123; Verapamil | 2021 |