verapamil has been researched along with caffeine in 228 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 62 (27.19) | 18.7374 |
| 1990's | 61 (26.75) | 18.2507 |
| 2000's | 40 (17.54) | 29.6817 |
| 2010's | 61 (26.75) | 24.3611 |
| 2020's | 4 (1.75) | 2.80 |
| Authors | Studies |
|---|---|
| Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL | 1 |
| Faassen, F; Spanings, H; Vogel, G; Vromans, H | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Akamatsu, M; Fujikawa, M; Nakao, K; Shimizu, R | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahman, M; Holmén, AG; Wan, H | 1 |
| Andrisano, V; Barril, X; Bartolini, M; Carreiras, Mdo C; de los Ríos, C; García, AG; Huertas, O; León, R; López, B; López, MG; Luque, FJ; Marco-Contelles, J; Rodríguez-Franco, MI; Samadi, A; Villarroya, M | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chen, L; He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Wang, Y; Zhang, W | 1 |
| Andrisano, V; Arce, MP; Badia, A; Bartolini, M; Camps, P; Clos, MV; Dafni, T; Formosa, X; Galdeano, C; Gómez, E; Huertas, O; Isambert, N; Lavilla, R; Luque, FJ; Mancini, F; Muñoz-Torrero, D; Ramírez, L; Rodríguez-Franco, MI | 1 |
| Du-Cuny, L; Mash, EA; Meuillet, EJ; Moses, S; Powis, G; Song, Z; Zhang, S | 1 |
| Arce, MP; Conde, S; García, AG; González-Muñoz, GC; López, B; López, MG; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Conradi, R; Lee, PH; Shanmugasundaram, V | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Avdeef, A; Tam, KY | 1 |
| Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ | 1 |
| Akamatsu, M | 1 |
| Sen, S; Sinha, N | 1 |
| Arce, MP; Conde, S; del Barrio, L; Egea, J; García, AG; González-Muñoz, GC; León, R; López, B; López, MG; Martín-de-Saavedra, MD; Pérez, C; Rodríguez-Franco, MI; Romero, A; Villarroya, M | 1 |
| Annand, R; Gozalbes, R; Jacewicz, M; Pineda-Lucena, A; Tsaioun, K | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Doh-Ura, K; Go, ML; Nguyen, T; Sakasegawa, Y | 1 |
| Caradonna, NP; Hallifax, D; Houston, JB; Turlizzi, E; Zanelli, U | 1 |
| Barber, S; Dew, TP; Farrell, TL; Poquet, L; Williamson, G | 1 |
| Brea, J; Cadavid, MI; Campillo, NE; Ceballos, P; Gil, C; Loza, MI; Martínez, A; Moro, MA; Pérez, C; Pérez, DI; Perez-Castillo, A; Redondo, M; Val, C; Zarruk, JG | 1 |
| Andrisano, V; Bolognesi, ML; Carloni, P; Cavalli, A; Chiriano, G; De Simone, A; Legname, G; Mancini, F; Martinez, A; Perez, DI; Roberti, M | 1 |
| Alonso-Gil, S; Campillo, NE; Castro, A; Encinas, A; Gil, C; Martinez, A; Morales-Garcia, JA; Palomo, V; Perez, C; Perez, DI; Perez-Castillo, A; Soteras, I | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Alonso-Gil, S; Chavarría, C; Gil, C; Morales Garcia, JA; Pérez, C; Perez, DI; Pérez-Castillo, A; Porcal, W; Souza, JM | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bello, ML; Gil, C; Kraemer, BC; Lecourtois, M; Liachko, NF; Martinez, A; Miguel, L; Perez, C; Perez, DI; Redondo, M; Salado, IG | 1 |
| Deng, Y; Li, Y; Liu, Q; Qiang, X; Sang, Z; Tan, Z; Xiao, G | 1 |
| Jiang, N; Kong, LY; Lan, JS; Li, ZR; Wang, KD; Wang, X; Xie, SS; Yu, W | 1 |
| Cahlíková, L; Chlebek, J; Hošt'álková, A; Opletal, L; Pérez, DI; Šafratová, M; Štěpánková, Š | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Deng, Y; Li, Y; Luo, L; Qiang, X; Tan, Z; Xiao, G | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Sang, Z; Su, F; Xiao, G; Yang, X; Zheng, Y | 1 |
| Ai, J; Deng, Y; Li, Y; Liu, Q; Luo, L; Qiang, X; Tan, Z; Xiao, G; Yang, X | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Sang, Z; Su, F; Xiao, G; Xu, R; Yang, X; Zheng, Y | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Tan, Z; Xu, R; Yang, X; Zheng, Y | 1 |
| Cao, Z; Deng, Y; Li, Y; Luo, L; Qiang, X; Song, Q; Tan, Z; Xiao, G; Xu, R; Yang, X | 1 |
| Arce, MP; Conde, S; Egea, J; Gil, C; León, R; López, MG; Monjas, L; Pérez, C; Rodríguez-Franco, MI; Villarroya, M | 1 |
| Bai, P; Leng, C; Li, X; Liu, W; Ma, Q; Pan, W; Sang, Z; Tan, Z; Wang, K; Xu, Q; Yang, Y; Yu, L | 1 |
| Liu, W; Ma, Q; Pan, W; Sang, Z; Wang, K; Yu, L | 1 |
| Campillo, NE; Geiger, L; Gil, C; González, S; Li, L; Martinez, A; Morales, AV; Perez, DI; Salado, IG; Sebastián-Pérez, V; Zaldivar-Diez, J | 1 |
| Han, X; Liu, W; Ma, Q; Sang, Z; Wang, H; Wang, K; Ye, M; Yu, L | 2 |
| Campillo, NE; Cañada, FJ; Canales, A; Carvalho, I; Chierrito, TPC; Martinez, A; Martínez-Gonzalez, L; Pedersoli-Mantoani, S; Perez, C; Pérez, DI; Roca, C; Sebastian-Pérez, V | 1 |
| Huang, Q; Jiang, N; Li, Q; Liang, N; Liu, J; Xie, SS | 1 |
| Cao, Z; Deng, Y; Li, Y; Liu, H; Qiang, X; Song, Q; Tan, Z; Xu, R; Yang, J; Zhang, X | 1 |
| Handzlik, J; Jastrzębska-Więsek, M; Kieć-Kononowicz, K; Kucwaj-Brysz, K; Latacz, G; Lubelska, A; Partyka, A; Wesołowska, A | 1 |
| Deng, Y; Li, Y; Liu, H; Song, Q; Tan, Z; Xiao, G; Xu, R; Yang, Z; Zhang, X; Zheng, Y | 1 |
| An, Q; Deng, Y; Liu, P; Luo, Y; Sang, Z; Tang, Y; Wang, T; Yang, T; Yang, Y; Zhang, T | 1 |
| Abdel-Raziq, MS; Gabr, MT | 1 |
| Alcaro, S; Bagetta, D; Borges, F; Cagide, F; Oliveira, PJ; Ortuso, F; Pérez, C; Reis, J; Rodríguez-Franco, MI; Teixeira, J; Uriarte, E; Valencia, ME | 1 |
| Cao, Z; Deng, Y; Li, Y; Liu, H; Qiang, X; Song, Q; Tan, Z; Tian, C; Yang, Z | 1 |
| Deng, Y; He, Y; Li, W; Liu, H; Qiang, X; Song, Q; Tan, Z; Ye, C | 1 |
| Liu, W; Sang, Z; Shi, J; Tan, Z; Wang, K | 1 |
| Liu, W; Sang, Z; Shi, J; Tan, Z; Wang, K; Zhang, P | 1 |
| Fan, X; Liu, W; Sang, Z; Shi, J; Wang, K; Yang, D; Zhang, P; Zhang, Z; Zhu, G | 1 |
| Bai, P; Cheng, X; Cheng, Y; Lu, X; Sang, Z; Shi, J; Wang, K; Yang, J; Zhang, P; Zhang, Q; Zheng, C | 1 |
| Balliano, TL; Barbosa, G; Carvalho, VF; da Silva, BA; de Souza, ET; Lima, LM; Martins, IRR; Martins, MA; Medeiros, MM; Moraes Junior, MO; Nunes, IKDC; Silva, PMR; Silva, SWD | 1 |
| Chen, H; Ding, H; Gao, Y; Jiang, X; Liu, W; Liu, X; Tian, L; Xu, Z; Zhao, Q | 1 |
| Brazzolotto, X; Bucki, A; Gobec, S; Godyń, J; Góral, I; Głuch-Lutwin, M; Honkisz-Orzechowska, E; Knez, D; Kołaczkowski, M; Latacz, G; Malawska, B; Panek, D; Pasieka, A; Sabate, R; Siwek, A; Wichur, T; Więckowska, A | 1 |
| Chaikuad, A; de Lago, E; Gil, C; Gomez-Almeria, M; Gonzalo-Consuegra, C; Knapp, S; Lietha, D; Martín-Requero, A; Martinez, A; Martínez-González, L; Monti, B; Nozal, V; Palomo, V; Pérez-Cuevas, E; Petralla, S; Ramírez, D; Santana, P | 1 |
| Wabnitz, RW | 1 |
| Bondi, AY | 1 |
| Kato, K; Linuma, H | 1 |
| Bogdanov, KIu; Rozenshtraukh, LV; Zakharov, SI | 3 |
| Bogdanov, KY; Rosenshtraukh, LV; Zakharov, SI | 1 |
| Hiraoka, M; Okamoto, Y; Sano, T | 1 |
| Chiba, S; Furukawa, Y; Kobayashi, M | 1 |
| Fleckenstein, A; Grün, G | 1 |
| Carvalho, AP; Garcia, EA | 1 |
| Ohkawa, H; Watanabe, M | 1 |
| Hoffmann, A; Siegers, CP; Sierra-Callejas, JL; Strubelt, O | 1 |
| Kuriyama, H; Suzuki, H | 1 |
| Bassett, AL; Wiggins, JR | 1 |
| Christie, A; Sharma, VK; Sheu, SS | 1 |
| Huang, LJ; Huang, TF; Kuo, SC; Sun, SS; Teng, CM; Yu, SM | 1 |
| Gwathmey, JK | 1 |
| Chen, CF; Chiou, WF; Yen, MH | 1 |
| Bosteels, S; Busselen, P; Tunstall, J | 1 |
| Moriyama, K; Shimamura, K; Sunano, S | 1 |
| Gaasch, WH; Zile, MR | 1 |
| Fabrègues, E; John, GW; Kamal, M; Massingham, R | 1 |
| Henschel, L; Hoffmann, A; Sigusch, H | 1 |
| Briggs, GM; Callahan, M; Copelas, L; Feldman, MD; Grossman, W; Gwathmey, JK; Morgan, JP; Phillips, PJ; Schoen, FJ; Warren, SE | 1 |
| Amobi, N; Smith, IC | 1 |
| Dhalla, NS; Gupta, MP; Kaneko, M; Makino, N; Takeo, S | 1 |
| Fletcher, JE; Huggins, FJ; Rosenberg, H | 1 |
| Hatae, J; Kawata, H | 1 |
| Aomine, M | 1 |
| Adamantidis, MM; Adnet, PJ; Dupuis, BA; Haudecoeur, G; Krivosic-Horber, RM; Reyfort, GH | 1 |
| Mori, T; Taira, N; Yanagisawa, T | 1 |
| Davidson, M; Shanley, B; Wilce, P | 1 |
| Bennett, T; Mangroo, T; Neves, M; Rahmani, MA | 1 |
| Auclair, MC; Lechat, P; Vernimmen, C | 1 |
| Kim, D; Smith, TW | 1 |
| Smits, P; Thien, T; van 't Laar, A | 1 |
| Ishii, T; Shimo, Y | 1 |
| Aldenhoff, JB | 1 |
| Ashida, T; Blaustein, MP | 1 |
| Savage, AO | 1 |
| Ubeda, A; Villar, A | 1 |
| Cariello, L; Nelson, L | 1 |
| Bers, DM; Merrill, DB | 1 |
| Denborough, MA; Foster, PS; Hopkinson, KC | 1 |
| Lamar, JC; Leboeuf, J; Leoty, C; Massingham, R | 1 |
| Hester, RK; Satake, N; Shibata, S; Tomiyama, A; Ueda, S; Wakabayashi, S | 1 |
| Ferrer, R; Soria, B | 1 |
| Koley, BN; Koley, J; Saha, JK | 1 |
| Atanga, KG; Savage, AO | 1 |
| Esau, SA | 1 |
| Cortijo, J; Esplugues, J; Morcillo, EJ; Ortiz, JL; Perpiñá, M; Sanz, C | 1 |
| Delbono, O; Muchnik, S; Obejero Paz, CA | 1 |
| Birkett, DJ; Matthews, AP; McManus, ME; Meller, D; Miners, JO; Robson, RA; Stupans, I | 1 |
| Peng, HB; Zhu, DL | 1 |
| Benedetti, M; Frank, C; Sagratella, S; Scotti de Carolis, A | 1 |
| Hasegawa, M; Kanaide, H; Kobayashi, S; Matsumoto, T; Nakamura, M; Nishimura, J; Shogakiuchi, Y | 1 |
| Tomita, K; Tsuchiya, H | 1 |
| Ahn, HY; Karaki, H; Urakawa, N | 1 |
| Bourdillon, PD; Grossman, W; Paulus, WJ; Serizawa, T | 1 |
| Alya, G; Feletou, M; Tricoche, R; Walden, M | 1 |
| Kotsias, BA; Muchnik, S; Obejero Paz, CA | 1 |
| Chappell, S; Henderson, A; Lewis, M | 1 |
| Biscardi, H; Bockman, EL; Deuster, PA; Muldoon, SM | 1 |
| Sharma, VK; Sheu, SS; Uglesity, A | 1 |
| Clodi, PH; Hartl, O | 1 |
| Bentley, PJ; Chiarandini, DJ | 1 |
| Byon, KY; Fleckenstein, A | 1 |
| Schneider, JA; Shigenobu, K; Sperelakis, N | 1 |
| Albuquerque, EX; Daly, JW; Kauffman, FC; Tamburini, R | 1 |
| Delgado, C; Diez, J; Tamargo, J | 1 |
| Hiraoka, M; Kawano, S | 2 |
| Fox, IJ; Swayze, CR; Wahler, GM | 1 |
| Aoyama, T; Ono, H; Sato, T | 1 |
| Brady, RC; Hilfer, SR | 1 |
| Aubier, M; Lecocguic, Y; Murciano, D; Pariente, R; Viires, N | 1 |
| Webb, RC | 1 |
| Pang, DC | 1 |
| Chuck, LH; Parmley, WW | 1 |
| Callewaert, G; Carmeliet, E; Porciatti, F; Sipido, KR; Vereecke, J | 1 |
| Chapunoff, D; Herman, CA; Romero, MA; Schulmeister, K; Skarda, S; Torres, OA | 1 |
| Blaustein, MP; Goldman, WF; Juhaszova, M; Krueger, BK; Yarowsky, PJ | 1 |
| Keirstead, SA; Miller, RF | 1 |
| Denborough, MA; Foster, PS | 1 |
| de Vicente, ML; Encinas, T; González, F; Rodríguez, C; San Andrés, MD; San Andrés, MI | 1 |
| D'Ocon, MP; Noguera, MA | 1 |
| Cortijo, J; Morcillo, EJ; Orón, JD; Perpiñá, M | 1 |
| Akera, T; Jiang, J; Temma, K | 1 |
| Cortijo, J; Morcillo, EJ; Sanz, CM; Small, RC; Villagrasa, V | 1 |
| Chang, YI; Su, JY; Tang, LJ | 1 |
| Antón, M; Cortijo, J; Morcillo, E; Santamaría, P; Villagrasa, V | 1 |
| Bassani, JW; Bers, DM; Qi, M; Samarel, AM | 1 |
| Dohi, Y; Kojima, M; Sato, K | 1 |
| Bingmann, D; Düsing, R; Grunze, H; Liu, Z; Mayer, A; Schirrmacher, K; Walden, J | 1 |
| Atarashi, H; Hayakawa, H; Hirayama, Y; Saitoh, H | 1 |
| Jones, R; Kilbane, E; Klette, K; Levine, B; Smith, ML | 1 |
| Bhatnagar, A; Castro, GJ | 1 |
| Brundage, RA; Fay, FS; Fogarty, KE; Tuft, RA | 1 |
| Goldman, WF; Salvaterra, CG | 1 |
| Matlib, MA; Motley, ED; Paul, RJ | 1 |
| Cody, DB; Isfort, RJ; LeBoeuf, RA; Ridder, GM; Stuard, SB | 1 |
| Su, JY | 1 |
| Farley, JM; Liu, X | 1 |
| Dukhanin, AS; Galenko-Iaroshevskiĭ, PA; Khankoeva, AI; Sergeev, PV | 1 |
| Hayashi, H; Katoh, H; Noda, N; Satoh, H; Terada, H; Yamazaki, N | 1 |
| Asano, M; Imaizumi, Y; Ito, K; Ito, KM; Kuwako, M; Nomura, Y; Uyama, Y; Watanabe, M | 1 |
| Li, G; Pralong, WF; Wollheim, CB | 1 |
| Baartscheer, A; Fiolet, JW; Opthof, T; Schumacher, CA | 1 |
| Sheng, JZ; Wang, HX; Wong, TM; Zhang, WM | 1 |
| Kwan, CY; Wang, HX; Wong, TM | 1 |
| Guibert, C; Marthan, R; Roux, E; Savineau, JP | 1 |
| Eusebi, F; Giovannelli, A; Lorenzon, P; Ragozzino, D; Ruzzier, F | 1 |
| Bonazzola, P; Consolini, A; Marquez, MT; Ponce-Hornos, JE | 1 |
| Hasegawa, T; Matsushita, M; Nishimura, M; Satoh, E; Shimizu, Y; Taquahashi, Y | 1 |
| Bartoli, P; Bonechi, F; Brandinelli, A; Del Rosso, A; Fradella, G; Ieri, A; Maioli, M; Mannelli, M; Mazza, F; Russo, L; Sansoni, M; Zipoli, A | 1 |
| Biggs, AV; Goknur, AB; Haworth, RA; Potter, KT; Redon, D | 1 |
| Chowdhury, JU; Nahar, NS; Torihashi, S | 1 |
| Aardal, S; Helle, KB; Lillestłl, IK | 1 |
| Gromadka, R; Kucharczyk, R; Migdalski, A; Rytka, J; Slonimski, PP | 1 |
| Hayashi, M; Ichihara, A; Miyashita, Y; Naitoh, M; Saruta, T; Suzuki, H | 1 |
| Guan, Z; Saqr, HE; Stokes, BT; Yates, AJ | 1 |
| Sadzuka, Y; Sonobe, T; Sugiyama, T | 1 |
| Favini, R; Fu, X; Kindahl, K; Ulmsten, U | 1 |
| Aaronson, PI; Hague, D; Robertson, TP; Ward, JP | 1 |
| Boyden, PA; Pu, J; Robinson, RB | 1 |
| Asbun, J; Castillo, EF; Ceballos, G; del Carmen Castillo, M; Henkel, CC | 1 |
| Chang, JP; Johnson, JD; Kwong, P; Wong, CJ; Yunker, WK | 1 |
| Beller, GA; Glover, DK; Linden, J; Macdonald, TL; Rieger, JM; Riou, LM; Ruiz, M; Watson, DD | 1 |
| Kawata, K; Komori, M; Sekiguchi, F; Sunano, S | 1 |
| Dierkes, PW; Hochstrate, P; Schlue, WR; Wende, V | 1 |
| Arruebo, MP; Grasa, L; Murillo, MD; Plaza, MA; Rebollar, E | 1 |
| Ertunc, M; Onur, R; Sara, Y | 1 |
| Shinozaki, T; ter Keurs, HE; Wilkens, JL; Yazawa, T | 1 |
| Ponce-Hornos, JE; Savio-Galimberti, E | 1 |
| Bhatt, AP; Cardenas, L; Hepler, PK; Holdaway-Clarke, TL; Justus, CD; Lazzaro, MD; Phillips, MS | 1 |
| Manju, L; Nair, RR | 1 |
| Amit, M; Binah, O; Danon, A; Dolnikov, K; Gerecht-Nir, S; Itskovitz-Eldor, J; Shilkrut, M; Zeevi-Levin, N | 1 |
| Atalik, KE; Dogan, N; Sahin, AS | 1 |
| Bulaeva, SV; Chuchkanov, FA; Maimistova, AA; Muravyov, AV; Yakusevich, VV; Zaitsev, LG | 1 |
| Huerta, M; Muñiz, J; Sánchez-Pastor, E; Shabala, L; Shabala, S; Trujillo, X | 1 |
| Du, J; Pan, G; Sun, L; Wang, L; Yang, B; Zhang, G; Zhang, Y | 1 |
| Horvath, B; Kesmarky, G; Toth, K; Vekasi, J | 1 |
| Chen, J; Chen, MT; Gundersen, MA; Valderrábano, M; Vernier, PT; Wang, S | 1 |
| Gilani, AH; Shah, AJ | 1 |
| Döndaş, NY; Kaplan, M; Kaya, D; Singirik, E | 1 |
| Ertunc, M; Korkusuz, P; Onur, R; Sara, Y | 1 |
| Baptista, BB; Farah, LS; Granado e Sá, M; Leite, VP; Zanotto, FP | 1 |
| Aragon, CM; Baliño, P; Pastor, R | 1 |
| Abuznait, AH; Burk, D; Cain, C; Ingram, D; Kaddoumi, A | 1 |
| Abuznait, AH; Kaddoumi, A; Patrick, SG | 1 |
| Alves, RS; de Siqueira, RJ; Fonseca-Magalhães, PA; Jorge, RJ; Magalhães, PJ; Martins, AM; Meneses, GC; Monteiro, HS; Sousa, DF | 1 |
| Nurullahoğlu-Atalık, KE | 1 |
| Brightling, CE; Challiss, RA; Gomez, E; Hollins, F; Saunders, R; Sweeney, D | 1 |
| Custódio, MR; Ortega, P; Zanotto, FP | 1 |
| Harris, G; Landesmann, B; Mennecozzi, M; Palosaari, T; Whelan, M | 1 |
2 review(s) available for verapamil and caffeine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Ca uptake by heart cells: I. Ca uptake by the sarcoplasmic reticulum of intact heart cells in suspension.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Cardiotonic Agents; Cell Compartmentation; Cell Size; Central Nervous System Stimulants; Electric Stimulation; Female; Heart; Ion Transport; Isoproterenol; Mitochondria, Heart; Myocardial Contraction; Myocardium; Rats; Sarcoplasmic Reticulum; Suspensions; Thapsigargin; Verapamil | 1998 |
1 trial(s) available for verapamil and caffeine
| Article | Year |
|---|---|
Influence of slow calcium-channel blockade on the cardiovascular effects of coffee.
Topics: Adult; Blood Pressure; Caffeine; Calcium Channel Blockers; Coffee; Female; Forearm; Heart Rate; Hemodynamics; Humans; Ion Channels; Male; Regional Blood Flow; Renin; Verapamil | 1986 |
225 other study(ies) available for verapamil and caffeine
| Article | Year |
|---|---|
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium | 1985 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Cheminformatic models to predict binding affinities to human serum albumin.
Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids | 2001 |
Caco-2 permeability, P-glycoprotein transport ratios and brain penetration of heterocyclic drugs.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain; Caco-2 Cells; Cell Membrane Permeability; Heterocyclic Compounds; Humans; Protein Transport | 2003 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
QSAR study on permeability of hydrophobic compounds with artificial membranes.
Topics: Biological Transport; Caco-2 Cells; Drug Evaluation, Preclinical; Humans; Hydrophobic and Hydrophilic Interactions; Membranes, Artificial; Permeability; Pharmaceutical Preparations; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry | 2009 |
Tacripyrines, the first tacrine-dihydropyridine hybrids, as multitarget-directed ligands for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Blood-Brain Barrier; Butyrylcholinesterase; Calcium; Calcium Channel Blockers; Catalytic Domain; Cell Death; Cell Line, Tumor; Cholinesterase Inhibitors; Cytosol; Dihydropyridines; Humans; Hydrogen Peroxide; Kinetics; Ligands; Models, Molecular; Peptide Fragments; Permeability; Tacrine | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Prediction of volume of distribution values in human using immobilized artificial membrane partitioning coefficients, the fraction of compound ionized and plasma protein binding data.
Topics: Blood Proteins; Chemistry, Physical; Computer Simulation; Humans; Membranes, Artificial; Models, Biological; Pharmaceutical Preparations; Protein Binding; Tissue Distribution | 2009 |
Pyrano[3,2-c]quinoline-6-chlorotacrine hybrids as a novel family of acetylcholinesterase- and beta-amyloid-directed anti-Alzheimer compounds.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Binding Sites; Blood-Brain Barrier; Butyrylcholinesterase; Cattle; Cholinesterase Inhibitors; Drug Design; Humans; Isomerism; Membranes, Artificial; Mice; Models, Molecular; Molecular Conformation; Permeability; Protein Binding; Tacrine | 2009 |
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain.
Topics: Antineoplastic Agents; Blood Proteins; Caco-2 Cells; Cell Membrane Permeability; Computer Simulation; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Phosphoproteins; Protein Binding; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Quantitative Structure-Activity Relationship | 2009 |
Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Catalytic Domain; Cattle; Cell Death; Cell Line, Tumor; Cell Survival; Cholinergic Agents; Cholinesterase Inhibitors; Esters; Glutamic Acid; Humans; Hydrophobic and Hydrophilic Interactions; Neuroprotective Agents; Permeability; Piperidines; Protein Binding | 2009 |
Development of an in silico model for human skin permeation based on a Franz cell skin permeability assay.
Topics: 1-Methyl-3-isobutylxanthine; Cell Line; Cell Membrane Permeability; Humans; Models, Biological; Quantitative Structure-Activity Relationship; Skin Absorption | 2010 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics | 2010 |
Importance of physicochemical properties for the design of new pesticides.
Topics: Anabasine; Animals; Biological Availability; Cell Membrane Permeability; Chemical Phenomena; Drug Design; Humans; Imidazoles; Insecticides; Neonicotinoids; Nitro Compounds; Pesticides; Quantitative Structure-Activity Relationship; Receptors, Nicotinic | 2011 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antineoplastic Agents; Butyrylcholinesterase; Calcium; Cell Death; Cell Survival; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Molecular Structure; Okadaic Acid; Peptide Fragments; Phenothiazines; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 2011 |
QSAR-based permeability model for drug-like compounds.
Topics: Caco-2 Cells; Cell Membrane Permeability; Drug Discovery; Humans; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2011 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
Anti-prion activities and drug-like potential of functionalized quinacrine analogs with basic phenyl residues at the 9-amino position.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport; Blood-Brain Barrier; Cell Line, Tumor; Dogs; Humans; Madin Darby Canine Kidney Cells; Mice; Peptide Fragments; Permeability; Piperazines; Piperidines; Prion Diseases; Prions; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Quinacrine; Recombinant Proteins; Structure-Activity Relationship | 2011 |
Comparison of cryopreserved HepaRG cells with cryopreserved human hepatocytes for prediction of clearance for 26 drugs.
Topics: Cell Line, Tumor; Cryopreservation; Female; Hepatocytes; Humans; Male; Metabolic Clearance Rate; Pharmaceutical Preparations; Predictive Value of Tests | 2012 |
Predicting phenolic acid absorption in Caco-2 cells: a theoretical permeability model and mechanistic study.
Topics: Artificial Intelligence; Caco-2 Cells; Cell Membrane Permeability; Cinnamates; Enterocytes; Humans; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Kinetics; Models, Biological; Molecular Conformation; Osmolar Concentration; Phenols | 2012 |
Neuroprotective efficacy of quinazoline type phosphodiesterase 7 inhibitors in cellular cultures and experimental stroke model.
Topics: Animals; Blood-Brain Barrier; Cells, Cultured; Cyclic Nucleotide Phosphodiesterases, Type 7; Disease Models, Animal; Enzyme Inhibitors; Infarction, Middle Cerebral Artery; Male; Mice; Neuroprotective Agents; Permeability; Quinazolines; Stroke | 2012 |
A small chemical library of 2-aminoimidazole derivatives as BACE-1 inhibitors: Structure-based design, synthesis, and biological evaluation.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid Precursor Protein Secretases; Animals; Cell Survival; Chickens; Humans; Imidazoles; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Models, Molecular; Neurons; Small Molecule Libraries; Spectrometry, Mass, Electrospray Ionization; Spectroscopy, Fourier Transform Infrared; Structure-Activity Relationship | 2012 |
5-imino-1,2,4-thiadiazoles: first small molecules as substrate competitive inhibitors of glycogen synthase kinase 3.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Blood-Brain Barrier; Cell Death; Cell Differentiation; Cell Membrane Permeability; Cells, Cultured; Glycogen Synthase Kinase 3; Hippocampus; Humans; Imines; In Vitro Techniques; Lipopolysaccharides; Membranes, Artificial; Microglia; Models, Molecular; Neural Stem Cells; Neurogenesis; Neurons; Neuroprotective Agents; Nitrites; Protein Binding; Rats; Structure-Activity Relationship; Substrate Specificity; Swine; Thiadiazoles | 2012 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Microwave-assisted synthesis of hydroxyphenyl nitrones with protective action against oxidative stress.
Topics: Anti-Inflammatory Agents; Antioxidants; Blood-Brain Barrier; Cell Survival; Dose-Response Relationship, Drug; Humans; Microwaves; Molecular Structure; Neuroblastoma; Neuroprotective Agents; Nitrogen Oxides; Oxidative Stress; Oxidopamine; Peroxynitrous Acid; Structure-Activity Relationship; Tyrosine | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Benzothiazoles; Blood-Brain Barrier; Casein Kinase I; Cell Membrane Permeability; Cells, Cultured; DNA-Binding Proteins; Drosophila; Drug Design; Drug Discovery; HEK293 Cells; Heterocyclic Compounds; High-Throughput Screening Assays; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Neurons; Neurotoxicity Syndromes; Phosphorylation; Protein Kinase Inhibitors; Substrate Specificity | 2014 |
Multifunctional scutellarin-rivastigmine hybrids with cholinergic, antioxidant, biometal chelating and neuroprotective properties for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Apigenin; Blood-Brain Barrier; Butyrylcholinesterase; Carbamates; Cell Line; Chelating Agents; Cholinesterase Inhibitors; Cognition; Glucuronates; Humans; Mice; Molecular Docking Simulation; Neuroprotective Agents; Rats | 2015 |
Multi-target tacrine-coumarin hybrids: cholinesterase and monoamine oxidase B inhibition properties against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Benzopyrans; Blood-Brain Barrier; Brain; Cell Survival; Cells, Cultured; Cholinesterase Inhibitors; Coumarins; Drug Design; Erythrocytes; Humans; Kinetics; Models, Molecular; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroblastoma; Piperazines; Tacrine | 2015 |
In Vitro Inhibitory Effects of 8-O-Demethylmaritidine and Undulatine on Acetylcholinesterase and Their Predicted Penetration across the Blood-Brain Barrier.
Topics: Acetylcholinesterase; Alzheimer Disease; Amaryllidaceae Alkaloids; Biological Transport; Blood-Brain Barrier; Cholinesterase Inhibitors; Humans; In Vitro Techniques; Molecular Structure | 2015 |
Synthesis and evaluation of 4-hydroxyl aurone derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Benzofurans; Blood-Brain Barrier; Chelating Agents; Copper; Humans; Models, Molecular; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Peptide Fragments; Protein Aggregates; Swine | 2016 |
Multitarget drug design strategy against Alzheimer's disease: Homoisoflavonoid Mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties.
Topics: Acetylcholinesterase; Alzheimer Disease; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Isoflavones; Mannich Bases; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship | 2017 |
Aurone Mannich base derivatives as promising multifunctional agents with acetylcholinesterase inhibition, anti-β-amyloid aggragation and neuroprotective properties for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Mannich Bases; Neuroprotective Agents; PC12 Cells; Rats | 2017 |
Design, synthesis and biological evaluation of 4'-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Chalcones; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Humans; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Rivastigmine; Structure-Activity Relationship; Swine | 2017 |
DL-3-n-butylphthalide-Edaravone hybrids as novel dual inhibitors of amyloid-β aggregation and monoamine oxidases with high antioxidant potency for Alzheimer's therapy.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Antipyrine; Benzofurans; Binding Sites; Blood-Brain Barrier; Edaravone; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Protein Binding; Protein Structure, Tertiary | 2017 |
Multifunctional thioxanthone derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Cell Line; Cholinesterase Inhibitors; Humans; Kinetics; Models, Molecular; Monoamine Oxidase Inhibitors; Thioxanthenes; Xanthones | 2017 |
Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia.
Topics: Alzheimer Disease; Animals; Brain Ischemia; Calcium Channel Blockers; Cholinesterase Inhibitors; Donepezil; Glutamates; Hippocampus; Humans; Indans; Neuroprotective Agents; Piperidines; Rats; Solid-Phase Synthesis Techniques | 2017 |
Design, synthesis and evaluation of novel ferulic acid-O-alkylamine derivatives as potential multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Coumaric Acids; Drug Design; Eels; Humans; Memory Disorders; Mice; PC12 Cells; Rats | 2017 |
Design, synthesis and biological evaluation of 3,4-dihydro-2(1H)-quinoline-O-alkylamine derivatives as new multipotent cholinesterase/monoamine oxidase inhibitors for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Cholinesterase Inhibitors; Drug Design; Electrophorus; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quinolines; Swine | 2017 |
Leucine rich repeat kinase 2 (LRRK2) inhibitors based on indolinone scaffold: Potential pro-neurogenic agents.
Topics: Animals; Cell Differentiation; Cell Proliferation; Dose-Response Relationship, Drug; Humans; Indoles; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Mice; Mice, Inbred C57BL; Models, Molecular; Molecular Structure; Neural Stem Cells; Neuroprotective Agents; Protein Kinase Inhibitors; Structure-Activity Relationship | 2017 |
Design, synthesis and biological evaluation of phthalimide-alkylamine derivatives as balanced multifunctional cholinesterase and monoamine oxidase-B inhibitors for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amines; Binding Sites; Blood-Brain Barrier; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Cholinesterases; Drug Design; Humans; Inhibitory Concentration 50; Kinetics; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Phthalimides; Protein Structure, Tertiary; Structure-Activity Relationship | 2017 |
Design, synthesis and biological evaluation of 2-acetyl-5-O-(amino-alkyl)phenol derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Antioxidants; Benzophenones; Binding Sites; Blood-Brain Barrier; Cell Survival; Cholinesterase Inhibitors; Drug Design; Humans; Hydrogen Peroxide; Inhibitory Concentration 50; Molecular Docking Simulation; Monoamine Oxidase; Neuroprotective Agents; PC12 Cells; Permeability; Phenols; Piperazines; Protein Structure, Tertiary; Rats; Structure-Activity Relationship | 2017 |
Chameleon-like behavior of indolylpiperidines in complex with cholinesterases targets: Potent butyrylcholinesterase inhibitors.
Topics: Acetylcholinesterase; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Indoles; Molecular Structure; Piperidines; Structure-Activity Relationship | 2018 |
Design, synthesis and biological evaluation of new coumarin-dithiocarbamate hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Cell Line, Tumor; Cholinesterase Inhibitors; Coumarins; Dose-Response Relationship, Drug; Drug Design; Humans; Kinetics; Male; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Peptide Fragments; Protein Aggregates; Range of Motion, Articular; Structure-Activity Relationship; Thiocarbamates | 2018 |
Design, synthesis and evaluation of 4'-OH-flurbiprofen-chalcone hybrids as potential multifunctional agents for Alzheimer's disease treatment.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Blood-Brain Barrier; Cell Line; Cell Survival; Chalcones; Chelating Agents; Copper; Drug Design; Flurbiprofen; Humans; Lipopolysaccharides; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Nitric Oxide; Peptide Fragments; Recombinant Proteins; Structure-Activity Relationship | 2018 |
MF-8, a novel promising arylpiperazine-hydantoin based 5-HT
Topics: Dose-Response Relationship, Drug; Humans; Hydantoins; Molecular Structure; Piperazines; Receptors, Serotonin; Serotonin Antagonists; Structure-Activity Relationship | 2018 |
Multifunctional 5,6-dimethoxybenzo[d]isothiazol-3(2H)-one-N-alkylbenzylamine derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Benzylamines; Blood-Brain Barrier; Cholinesterase Inhibitors; Drug Design; Humans; Kinetics; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Permeability; Protein Aggregates; Recombinant Proteins; Structure-Activity Relationship; Thiazoles | 2018 |
Discovery of novel anti-tuberculosis agents with pyrrolo[1,2-a]quinoxaline-based scaffold.
Topics: Antineoplastic Agents; Antitubercular Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Microbial Sensitivity Tests; Molecular Structure; Mycobacterium tuberculosis; Pyrroles; Quinoxalines; Structure-Activity Relationship | 2018 |
Structure-based design, synthesis, and evaluation of structurally rigid donepezil analogues as dual AChE and BACE-1 inhibitors.
Topics: Acetylcholinesterase; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Blood-Brain Barrier; Cell Line, Tumor; Cell Survival; Cholinesterase Inhibitors; Crystallography, X-Ray; Donepezil; Dose-Response Relationship, Drug; Drug Design; Humans; Models, Molecular; Molecular Structure; Structure-Activity Relationship | 2018 |
Multi-target-directed ligands for Alzheimer's disease: Discovery of chromone-based monoamine oxidase/cholinesterase inhibitors.
Topics: Alzheimer Disease; Blood-Brain Barrier; Cholinesterase Inhibitors; Cholinesterases; Chromones; Drug Design; Hep G2 Cells; Humans; Ligands; Molecular Docking Simulation; Molecular Targeted Therapy; Monoamine Oxidase; Monoamine Oxidase Inhibitors | 2018 |
Discovery of novel 2,5-dihydroxyterephthalamide derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Butyrylcholinesterase; Chelating Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Humans; Models, Molecular; Molecular Structure; Peptide Fragments; Phthalimides; Protein Aggregates; Structure-Activity Relationship | 2018 |
Discovery of 4'-OH-flurbiprofen Mannich base derivatives as potential Alzheimer's disease treatment with multiple inhibitory activities.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Blood-Brain Barrier; Cell Line; Cholinesterase Inhibitors; Drug Design; Drug Discovery; Electrophorus; Flurbiprofen; Humans; Mannich Bases; Molecular Docking Simulation; Peptide Fragments; Protein Aggregates; Rats; Swine | 2019 |
Design, synthesis, in-silico and biological evaluation of novel chalcone-O-carbamate derivatives as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Blood-Brain Barrier; Butyrylcholinesterase; Chalcones; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Design; Eels; Female; Horses; Humans; Male; Maze Learning; Mice; Mice, Inbred Strains; Models, Molecular; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Peptide Fragments; Protein Aggregates; Rats; Structure-Activity Relationship | 2019 |
Design, synthesis, in-silico and biological evaluation of novel chalcone derivatives as multi-function agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Chalcone; Cholinesterase Inhibitors; Drug Design; Eels; Horses; Humans; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Peptide Fragments; Protein Aggregates | 2019 |
The development of 2-acetylphenol-donepezil hybrids as multifunctional agents for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Cholinesterase Inhibitors; Cholinesterases; Donepezil; Drug Design; Drug Development; Humans; Kinetics; Models, Molecular; Molecular Docking Simulation; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Structure-Activity Relationship | 2019 |
Development of chalcone-O-alkylamine derivatives as multifunctional agents against Alzheimer's disease.
Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Biological Transport; Blood-Brain Barrier; Butyrylcholinesterase; Chalcones; Chelating Agents; Cholinesterase Inhibitors; Coordination Complexes; Copper; Drug Design; Female; Humans; Male; Memory Disorders; Mice; Molecular Docking Simulation; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Neuroprotective Agents; Protein Binding; Scopolamine; Structure-Activity Relationship | 2019 |
Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies.
Topics: Animals; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Drug Design; Enzyme Inhibitors; Humans; Hydrazones; Hypersensitivity; Lung; Male; Mice | 2020 |
Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease.
Topics: Alzheimer Disease; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Dyrk Kinases; Glycogen Synthase Kinase 3 beta; Harmine; Humans; Models, Molecular; Molecular Structure; Neuroprotective Agents; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Structure-Activity Relationship | 2021 |
Discovery of 1-(phenylsulfonyl)-1H-indole-based multifunctional ligands targeting cholinesterases and 5-HT
Topics: Acetylcholinesterase; Amyloid beta-Peptides; Animals; Butyrylcholinesterase; Cell Proliferation; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Discovery; Electrophorus; Hep G2 Cells; Horses; Humans; Indoles; Ligands; Mice; Microsomes, Liver; Molecular Docking Simulation; Molecular Structure; Protein Aggregates; Receptors, Serotonin; Structure-Activity Relationship; tau Proteins | 2021 |
TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy.
Topics: Amyotrophic Lateral Sclerosis; Animals; Brain; Case-Control Studies; DNA-Binding Proteins; Humans; Inflammation; Macrophages; Male; Mice; Mice, Inbred BALB C; Mice, Transgenic; Phosphorylation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Rats; Rats, Wistar; Spinal Cord; Tissue Distribution | 2022 |
Excitation-contraction coupling and intracellular calcium pool in the penis retractor muscle of Helix pomatia.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Electric Conductivity; Electric Stimulation; Helix, Snails; Male; Muscle Contraction; Muscles; Penis; Snails; Verapamil | 1976 |
Effects of verapamil on excitation-contraction coupling in frog sartorius muscle.
Topics: Animals; Anura; Caffeine; Calcium; Dantrolene; Drug Interactions; Electric Stimulation; Hydrogen-Ion Concentration; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscles; Potassium; Procaine; Rana pipiens; Verapamil | 1978 |
The effects of extracellular potassium and several drugs on the premature action potential and postextrasystolic potentiation.
Topics: Action Potentials; Animals; Caffeine; Calcium; Cardiac Complexes, Premature; Dogs; Extracellular Space; Heart Conduction System; Isoproterenol; Myocardial Contraction; Myocardium; Potassium; Verapamil | 1978 |
[Nature of the 2-component contraction of mammalian myocardium due to noradrenaline].
Topics: Action Potentials; Animals; Caffeine; Guinea Pigs; In Vitro Techniques; Myocardial Contraction; Norepinephrine; Papillary Muscles; Physical Stimulation; Verapamil | 1979 |
The origin of two components in contraction of guinea pig papillary muscle in the presence of noradrenaline.
Topics: Animals; Caffeine; Female; Guinea Pigs; In Vitro Techniques; Male; Myocardial Contraction; Norepinephrine; Papillary Muscles; Verapamil | 1979 |
Effects of Ca+ and K+ on oscillatory afterpotentials in dog ventricular muscle fibers.
Topics: Animals; Caffeine; Calcium; Dogs; Isoproterenol; Membrane Potentials; Myocardial Contraction; Potassium; Rubidium; Sodium; Ventricular Function; Verapamil | 1979 |
Effects of cardioactive substances on the post-stimulation potentiation of contractility in the isolated dog atrium.
Topics: Adenosine; Animals; Caffeine; Chlorides; Dogs; Electric Stimulation; Female; In Vitro Techniques; Male; Manganese; Myocardial Contraction; Ouabain; Pentobarbital; Propranolol; Tetrodotoxin; Verapamil | 1978 |
[Calcium-antagonism, a new principle in coronary vasodilation].
Topics: Animals; Caffeine; Calcium; Cardiac Glycosides; Chromonar; Coronary Vessels; Muscle Tonus; Muscle, Smooth; Nifedipine; Nitrites; Nitroglycerin; Papaverine; Prenylamine; Swine; Vasodilator Agents; Verapamil | 1975 |
[Effects of stimulation on the longitudal resistance of the myocardium].
Topics: Animals; Caffeine; Calcium; Dogs; Heart Conduction System; Heart Function Tests; Isoproterenol; Myocardial Contraction; Rabbits; Stimulation, Chemical; Verapamil | 1977 |
Effects of gastrointestinal hormones on the electrical and mechanical activity of the cat stomach.
Topics: Action Potentials; Animals; Atropine; Caffeine; Cats; Cholecystokinin; Gastrins; Gastrointestinal Hormones; Imidazoles; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Pyloric Antrum; Secretin; Stomach; Tetrodotoxin; Theophylline; Verapamil | 1977 |
On the pathogenesis of cardiac necroses induced by theophylline and caffeine.
Topics: Animals; Blood Pressure; Caffeine; Calcium; Gallopamil; Heart; Heart Rate; Isoproterenol; Male; Myocarditis; Myocardium; Necrosis; Oxygen Consumption; Propranolol; Rats; Theophylline; Verapamil | 1976 |
Electrical and mechanical properties of longitudinal and circular muscles of the guinea-pig ileum.
Topics: Animals; Atropine; Caffeine; Guinea Pigs; Ileum; In Vitro Techniques; Lanthanum; Membrane Potentials; Muscle Contraction; Muscle, Smooth; Procaine; Prostaglandins E; Tetrodotoxin; Verapamil | 1975 |
Caffeine and KC1 contracture in cat myocardium.
Topics: Animals; Caffeine; Calcium; Cats; Drug Interactions; In Vitro Techniques; Myocardial Contraction; Myocardium; Potassium Chloride; Procaine; Time Factors; Verapamil | 1976 |
Mechanism of extracellular ATP-induced increase of cytosolic Ca2+ concentration in isolated rat ventricular myocytes.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Caffeine; Calcium; Calcium Channels; Cells, Cultured; Cytosol; Extracellular Space; Heart; Heart Ventricles; Magnesium; Myocardium; Nimodipine; Rats; Ryanodine; Verapamil | 1992 |
Vasorelaxation of rat thoracic aorta caused by two Ca(2+)-channel blockers, HA-22 and HA-23.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Caffeine; Calcium Channel Blockers; Cromakalim; Cyclic AMP; Cyclic GMP; Female; In Vitro Techniques; Male; Nifedipine; Pyrans; Pyrazoles; Pyrroles; Rats; Rats, Inbred Strains; Vasodilation; Verapamil | 1992 |
Cellular mechanisms of paired electrical stimulation in ferret ventricular myocardium: relationship between myocardial force and stimulus interval change.
Topics: Animals; Caffeine; Calcium; Electric Stimulation; Ferrets; Heart Ventricles; In Vitro Techniques; Intracellular Fluid; Myocardial Contraction; Ryanodine; Sarcolemma; Sarcoplasmic Reticulum; Ventricular Function; Verapamil | 1992 |
Mechanism of vasodilatory effect of berberine in rat mesenteric artery.
Topics: Animals; Arginine; Berberine; Caffeine; Calcium Channels; Drug Interactions; Endothelium, Vascular; Female; Male; Mesenteric Arteries; Methylene Blue; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nitroarginine; Phenylephrine; Potassium; Rats; Rats, Inbred Strains; Vasodilator Agents; Verapamil | 1991 |
Caffeine rapid cooling contractures and negative force staircase in rat papillary muscle.
Topics: Action Potentials; Animals; Caffeine; Calcium; Isoproterenol; Manganese; Myocardial Contraction; Nickel; Potassium; Rats; Sarcoplasmic Reticulum; Sodium; Temperature; Tetrodotoxin; Verapamil | 1991 |
Caffeine-induced contraction of rat portal vein and effects of K-depolarization, Na-removal and low temperature.
Topics: Action Potentials; Animals; Caffeine; Calcium; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Portal Vein; Potassium; Procaine; Rats; Rats, Wistar; Ryanodine; Sodium; Temperature; Verapamil | 1991 |
Load-dependent left ventricular relaxation in conscious dogs.
Topics: Animals; Blood Pressure; Caffeine; Dogs; Heart Rate; Heart Ventricles; Hemodynamics; Myocardial Contraction; Propranolol; Regression Analysis; Verapamil | 1991 |
Caffeine-induced contractions in rabbit isolated renal artery are differentially inhibited by calcium antagonists.
Topics: Animals; Bepridil; Caffeine; Calcium Channel Blockers; Diltiazem; Dose-Response Relationship, Drug; Fendiline; Flunarizine; Kinetics; Lidoflazine; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nifedipine; Rabbits; Renal Artery; Verapamil | 1991 |
[The effects of verapamil and nifedipine on the biotransformation of model substances and on the indocyanine green elimination].
Topics: Adult; Biotransformation; Caffeine; Debrisoquin; Dipyrone; Humans; Indocyanine Green; Liver; Liver Circulation; Male; Nifedipine; Sulfamethazine; Verapamil | 1991 |
Diastolic dysfunction in hypertrophic cardiomyopathy. Effect on active force generation during systole.
Topics: Adult; Aged; Caffeine; Calcium; Cardiomyopathy, Hypertrophic; Colforsin; Diastole; Female; Hemodynamics; Humans; In Vitro Techniques; Isoproterenol; Male; Middle Aged; Myocardial Contraction; Strophanthidin; Systole; Verapamil | 1991 |
Paradoxical effects of thioridazine on electromechanical coupling in the human and rat vas deferens.
Topics: Animals; Biomechanical Phenomena; Caffeine; Calcimycin; Calcium Channel Blockers; Humans; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Rats; Thioridazine; Vas Deferens; Verapamil | 1991 |
Cardiac sarcolemma as a possible site of action of caffeine in rat heart.
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Biological Transport, Active; Ca(2+) Mg(2+)-ATPase; Caffeine; Calcium; Cardiotonic Agents; Dose-Response Relationship, Drug; Heart; Kinetics; Male; Myocardial Contraction; Myocardium; Rats; Rats, Inbred Strains; Sarcolemma; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil | 1990 |
The importance of calcium ions for in vitro malignant hyperthermia testing.
Topics: Caffeine; Calcium; Contracture; Drug Interactions; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Quinacrine; Strontium; Succinylcholine; Verapamil | 1990 |
Dependence of contractile responses by some calcium antagonists on external calcium in the skeletal muscle.
Topics: Animals; Caffeine; Calcium; Membrane Potentials; Muscle Contraction; Muscles; Nicardipine; Ranidae; Verapamil | 1990 |
The inhibitory actions of amiodarone on rested-state contraction in isolated guinea-pig ventricular muscle.
Topics: Amiodarone; Animals; Caffeine; Female; Guinea Pigs; In Vitro Techniques; Male; Microelectrodes; Myocardial Contraction; Papillary Muscles; Verapamil | 1990 |
Clinical concentrations of verapamil affect the in vitro diagnosis of susceptibility to malignant hyperpyrexia.
Topics: Caffeine; Disease Susceptibility; False Negative Reactions; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Sensory Thresholds; Verapamil | 1990 |
Histamine increases vascular tone and intracellular calcium level using both intracellular and extracellular calcium in porcine coronary arteries.
Topics: Animals; Benzofurans; Caffeine; Calcium; Coronary Vessels; Fura-2; Histamine; In Vitro Techniques; Microscopy, Fluorescence; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Potassium Chloride; Ryanodine; Swine; Verapamil | 1990 |
Ethanol and synaptosomal calcium homeostasis.
Topics: Animals; Brain; Caffeine; Calcium; Drug Interactions; Ethanol; Homeostasis; In Vitro Techniques; Lanthanum; Male; Ouabain; Potassium Cyanide; Rats; Rats, Inbred Strains; Synaptosomes; Verapamil | 1990 |
In vitro caffeine induced aortic smooth muscle reactivity in rat.
Topics: Animals; Aorta; Caffeine; Hypertension; In Vitro Techniques; Magnesium; Male; Muscle, Smooth, Vascular; Prazosin; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Rats, Inbred WKY; Vasoconstriction; Vasodilation; Verapamil; Yohimbine | 1990 |
[Effect of substances modifying calcium movement on the contractility of cultured cardiac cells].
Topics: Animals; Caffeine; Calcium Channel Blockers; Cells, Cultured; Diltiazem; Histamine; Imipramine; Ion Channels; Isoproterenol; Myocardial Contraction; Nifedipine; Phenylephrine; Rats; Verapamil | 1985 |
Effects of thyroid hormone on calcium handling in cultured chick ventricular cells.
Topics: Animals; Caffeine; Calcium; Cells, Cultured; Chick Embryo; Heart; Ion Channels; Myocardial Contraction; Myocardium; Potassium; Sarcolemma; Sarcoplasmic Reticulum; Time Factors; Triiodothyronine; Verapamil | 1985 |
Cooling-induced augmentation of the contractile response of the golden hamster tracheal muscle to substance P in-vitro.
Topics: Animals; Caffeine; Calcium; Carbachol; Cold Temperature; Cricetinae; In Vitro Techniques; Male; Mesocricetus; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Substance P; Trachea; Verapamil | 1986 |
Does corticotropin releasing factor act via a calcium-dependent mechanism?
Topics: Action Potentials; Animals; Caffeine; Calcium; Corticotropin-Releasing Hormone; Hippocampus; In Vitro Techniques; Ion Channels; Potassium; Rats; Verapamil | 1986 |
Regulation of cell calcium and contractility in mammalian arterial smooth muscle: the role of sodium-calcium exchange.
Topics: Animals; Aorta; Arteries; Caffeine; Calcium; Cattle; In Vitro Techniques; Ion Channels; Muscle Contraction; Muscle, Smooth, Vascular; Phentolamine; Rats; Rats, Inbred Strains; Sodium; Strophanthidin; Tail; Verapamil | 1987 |
A comparison of the actions of 4-aminopyridine, caffeine and quinine on the toad isolated rectus abdominis muscle.
Topics: 4-Aminopyridine; Aminopyridines; Animals; Bufonidae; Caffeine; Egtazic Acid; In Vitro Techniques; Manganese; Muscle Contraction; Muscle, Smooth; Neuromuscular Depolarizing Agents; Potassium; Procaine; Quinine; Verapamil | 1989 |
Relaxant actions of khellin on vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Female; In Vitro Techniques; Khellin; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Potassium; Rats; Rats, Inbred Strains; Verapamil | 1989 |
Adrenergic stimulation of sea urchin sperm cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Atenolol; Caffeine; Calcium; Heterocyclic Compounds; Male; Sea Urchins; Sperm Motility; Spermatozoa; Verapamil | 1989 |
The role of Ca influx in cardiac muscle excitation-contraction coupling. Assessment by extracellular Ca microelectrodes.
Topics: Animals; Caffeine; Calcium; Cardiac Pacing, Artificial; Cobalt; Culture Techniques; Electrocardiography; Extracellular Space; Ion Channels; Isoproterenol; Male; Myocardial Contraction; Papillary Muscles; Rabbits; Sarcoplasmic Reticulum; Sodium; Verapamil | 1985 |
Effect of diltiazem, verapamil and dantrolene on the contractility of isolated malignant hyperpyrexia-susceptible human skeletal muscle.
Topics: Caffeine; Dantrolene; Diltiazem; Disease Susceptibility; Halothane; Humans; In Vitro Techniques; Malignant Hyperthermia; Muscle Contraction; Potassium Chloride; Verapamil | 1989 |
Comparative effects of bepridil, its quaternary derivative CERM 11888 and verapamil on caffeine-induced contracture in ferret hearts.
Topics: Animals; Bepridil; Caffeine; Ferrets; In Vitro Techniques; Myocardial Contraction; Verapamil | 1989 |
Mode of vasorelaxing action of 5-[3-[[2-(3,4-dimethoxyphenyl)-ethyl]amino]-1-oxopropyl]-2,3,4,5- tetrahydro-1,5-benzothiazepine fumarate (KT-362), a new intracellular calcium antagonist.
Topics: Animals; Caffeine; Calcium Channel Blockers; Diltiazem; Egtazic Acid; Gallopamil; Lanthanum; Male; Methoxamine; Muscle Contraction; Nifedipine; Nitroglycerin; Norepinephrine; Rabbits; Thiazepines; Vasodilation; Verapamil | 1987 |
Graded spike electrogenesis in mouse pancreatic beta-cells.
Topics: Action Potentials; Animals; Caffeine; Cations, Divalent; Cell Membrane; Electric Conductivity; Glucose; Glyburide; Islets of Langerhans; Membrane Potentials; Tetrodotoxin; Verapamil | 1986 |
Effects of nicotine on spontaneous contractions of isolated atria of toad (Bufo melanostictus).
Topics: Animals; Atropine; Bufonidae; Caffeine; Edetic Acid; Hemicholinium 3; Hexamethonium Compounds; Hydroxydopamines; In Vitro Techniques; Myocardial Contraction; Nicotine; Oxidopamine; Physostigmine; Tyramine; Verapamil | 1987 |
Caffeine- and potassium-induced contractures of mouse isolated soleus muscle: effects of verapamil, manganese, EGTA and calcium withdrawal.
Topics: Animals; Biological Transport; Caffeine; Calcium; Dose-Response Relationship, Drug; Egtazic Acid; Female; In Vitro Techniques; Male; Manganese; Mice; Muscle Contraction; Potassium; Verapamil | 1988 |
Slowing of relaxation in the fatiguing hamster diaphragm is enhanced by theophylline.
Topics: Animals; Caffeine; Calcium; Cricetinae; Diaphragm; In Vitro Techniques; Mesocricetus; Muscle Contraction; Muscle Relaxation; Theophylline; Verapamil | 1988 |
The spasmogenic effect of caffeine in trachealis isolated from control and actively sensitized guinea-pigs.
Topics: Animals; Caffeine; Calcium; Dantrolene; Guinea Pigs; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; Temperature; Trachea; Trifluoperazine; Verapamil | 1988 |
The effect of verapamil and Ca free solution on mechanical and electrical properties in fast twitch mammalian skeletal muscle.
Topics: Action Potentials; Animals; Caffeine; Calcium; Electric Stimulation; Muscle Contraction; Muscles; Rats; Rats, Inbred Strains; Sarcoplasmic Reticulum; Solutions; Verapamil | 1987 |
Characterisation of theophylline metabolism by human liver microsomes. Inhibition and immunochemical studies.
Topics: Adult; Benzoflavones; Caffeine; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dextropropoxyphene; Humans; Immunologic Techniques; In Vitro Techniques; Isoenzymes; Kinetics; Microsomes, Liver; Middle Aged; Mixed Function Oxygenases; Theophylline; Verapamil | 1988 |
Increase in intracellular calcium induced by the polycation-coated latex bead, a stimulus that causes postsynaptic-type differentiation in cultured Xenopus muscle cells.
Topics: Animals; Anti-Bacterial Agents; Benzofurans; Caffeine; Calcium; Cell Differentiation; Cells, Cultured; Ethers; Fluorescent Dyes; Fura-2; Ionomycin; Ionophores; Microscopy, Fluorescence; Microspheres; Muscles; Neuromuscular Junction; Peptides; Verapamil; Xenopus laevis | 1988 |
Comparative influence of calcium blocker and purinergic drugs on epileptiform bursting in rat hippocampal slices.
Topics: Adenosine; Animals; Caffeine; Calcium; Epilepsy; Hippocampus; In Vitro Techniques; Magnesium; Male; Neurons; Nifedipine; Phenylisopropyladenosine; Pyramidal Tracts; Rats; Rats, Inbred Strains; Verapamil | 1988 |
Quin2 microfluorometry and effects of verapamil and diltiazem on calcium release from rat aorta smooth muscle cells in primary culture.
Topics: Aminoquinolines; Animals; Aorta; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Cytosol; Diltiazem; Male; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Norepinephrine; Rats; Verapamil | 1988 |
[The combined effect of anti-tumor agents with caffeine or calcium channel blockers on sarcoma cells by clonogenic assay].
Topics: Antineoplastic Combined Chemotherapy Protocols; Caffeine; Calcium Channel Blockers; Colony-Forming Units Assay; Drug Synergism; Drug Therapy, Combination; Humans; Osteosarcoma; Sarcoma; Tumor Stem Cell Assay; Verapamil | 1987 |
Caffeine-induced contraction in vascular smooth muscle.
Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; In Vitro Techniques; Lidocaine; Magnesium; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nitroprusside; Norepinephrine; Potassium; Procaine; Rabbits; Verapamil | 1987 |
Effects of verapamil on regional myocardial diastolic function in pacing-induced ischemia in dogs.
Topics: Animals; Caffeine; Cardiac Pacing, Artificial; Coronary Disease; Diastole; Dogs; Heart; Hemodynamics; Myocardial Contraction; Rest; Verapamil | 1986 |
Source of calcium and cholinergic contraction of the rat portal vein and the sheep coronary artery.
Topics: Acetylcholine; Animals; Atropine; Caffeine; Calcium; Cobalt; Coronary Vessels; Culture Media; Female; Muscle Contraction; Muscle, Smooth, Vascular; Parasympathetic Nervous System; Portal Vein; Rats; Rats, Inbred Strains; Sheep; Sodium; Verapamil | 1986 |
Co2+, low Ca2+, and verapamil reduce mechanical activity in rat skeletal muscles.
Topics: Action Potentials; Animals; Caffeine; Calcium; Calcium Channel Blockers; Cobalt; Membrane Potentials; Muscle Contraction; Muscles; Rats; Rats, Inbred Strains; Verapamil | 1986 |
Characterization of the mechanical behavior of isolated papillary muscle preparations of the ferret.
Topics: Animals; Caffeine; Calcium; Ferrets; Heart; In Vitro Techniques; Isometric Contraction; Isotonic Contraction; Male; Myocardial Contraction; Myocardium; Ouabain; Oxygen Consumption; Papillary Muscles; Species Specificity; Temperature; Verapamil | 1986 |
Verapamil and zero Ca2+ alter responses of cat muscle to halothane and caffeine.
Topics: Animals; Caffeine; Calcium; Cats; Dose-Response Relationship, Drug; Drug Synergism; Extracellular Space; Halothane; Muscle Contraction; Muscles; Verapamil | 1986 |
Na+-Ca2+ exchange contributes to increase of cytosolic Ca2+ concentration during depolarization in heart muscle.
Topics: Animals; Caffeine; Calcium; Cytosol; Ethers; Ionomycin; Male; Manganese; Mathematics; Membrane Potentials; Myocardium; Potassium; Rats; Rats, Inbred Strains; Sodium; Verapamil | 1986 |
[Therapy of arrhythmias].
Topics: Ajmaline; Arrhythmias, Cardiac; Atrial Fibrillation; Bradycardia; Caffeine; Cardiac Complexes, Premature; Digitalis Glycosides; Heart Block; Humans; Lidocaine; Metaproterenol; Phenytoin; Procainamide; Tachycardia; Ventricular Fibrillation; Verapamil | 1973 |
The effects of verapamil on metabolism and contractility of the toad skeletal muscle.
Topics: Acetylcholine; Animals; Bufo marinus; Caffeine; Calcium; Dinitrophenols; In Vitro Techniques; Muscle Contraction; Muscles; Oxygen Consumption; Potassium; Procaine; Propranolol; Succinylcholine; Tubocurarine; Verapamil | 1973 |
Proceedings: Prevention by Ca-antagonistic compounds (verapamil, D 600) of coronary smooth muscle contractures due to treatment with cardiac glycosides.
Topics: Animals; Caffeine; Calcium; Cardiac Glycosides; Coronary Vessels; Dipyridamole; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Prenylamine; Theophylline; Verapamil | 1974 |
Verapamil blockade of slow Na+ and Ca++ responses in myocardial cells.
Topics: Action Potentials; Age Factors; Animals; Bucladesine; Caffeine; Calcium; Cells, Cultured; Chick Embryo; Depression, Chemical; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Manganese; Microelectrodes; Myocardium; Perfusion; Sodium; Species Specificity; Tetrodotoxin; Time Factors; Verapamil | 1974 |
Inhibition of calcium-dependent ATPase from sarcoplasmic reticulum by a new class of indolizidine alkaloids, pumiliotoxins A, B, and 251D.
Topics: Alkaloids; Amphibian Venoms; Animals; Caffeine; Calcium-Transporting ATPases; Indolizines; Kinetics; Muscles; Piperidines; Rana pipiens; Rats; Sarcoplasmic Reticulum; Structure-Activity Relationship; Verapamil | 1981 |
An analysis of the positive inotropic effect of AR-L 115 BS on isolated rat atria.
Topics: Animals; Caffeine; Calcium; Cardiotonic Agents; Electric Stimulation; Heart Rate; Imidazoles; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardial Contraction; Practolol; Rats; Rats, Inbred Strains; Reserpine; Sinoatrial Node; Sodium; Verapamil | 1984 |
Oscillations of membrane potential and tension in canine ventricular muscle fibers.
Topics: Action Potentials; Animals; Caffeine; Calcium; Dogs; Electric Stimulation; Heart; In Vitro Techniques; Isoproterenol; Membrane Potentials; Myocardial Contraction; Potassium; Procaine; Rubidium; Verapamil | 1984 |
[3 types of mechanical noise in the papillary muscle of the rat].
Topics: Animals; Caffeine; In Vitro Techniques; Membrane Potentials; Muscle Tonus; Myocardial Contraction; Papillary Muscles; Rats; Verapamil | 1984 |
Regulation of delayed afterdepolarizations and aftercontractions in dog ventricular muscle fibres.
Topics: Animals; Caffeine; Calcium; Dogs; Electrocardiography; Heart Rate; Isoproterenol; Myocardial Contraction; Papillary Muscles; Potassium; Procaine; Ventricular Function; Verapamil | 1984 |
A Ca2+-dependent mechanism for the positive inotropic response to an increase in afterload in cat papillary muscle.
Topics: Animals; Aorta; Blood Pressure; Caffeine; Calcium; Cats; Heart; Heart Rate; In Vitro Techniques; Isometric Contraction; Isotonic Contraction; Myocardial Contraction; Papillary Muscles; Propranolol; Temperature; Verapamil | 1984 |
Mechanisms of slow contracture induced by potassium and caffeine in skeletal muscle of the dog.
Topics: Animals; Caffeine; Calcium Chloride; Chlorides; Diltiazem; Dogs; Kinetics; Manganese; Manganese Compounds; Muscle Contraction; Potassium; Potassium Chloride; Tetracaine; Verapamil | 1984 |
Optic cup formation: a calcium-regulated process.
Topics: Animals; Caffeine; Calcimycin; Calcium; Chick Embryo; Eye; Microscopy, Fluorescence; Organ Culture Techniques; Retina; Theophylline; Trifluoperazine; Verapamil | 1982 |
[Relationship between isometric and isotonic contractile responses of the mammalian myocardium].
Topics: Action Potentials; Animals; Biomechanical Phenomena; Caffeine; Calcium; Cold Temperature; Guinea Pigs; In Vitro Techniques; Myocardial Contraction; Verapamil | 1983 |
Diaphragmatic contractility enhanced by aminophylline: role of extracellular calcium.
Topics: Aminophylline; Animals; Caffeine; Calcium; Calcium Channel Blockers; Diaphragm; Dogs; Dose-Response Relationship, Drug; Extracellular Space; Muscle Contraction; Verapamil | 1983 |
D-600 and the membrane stabilizing effect of calcium in vascular smooth muscle.
Topics: Animals; Caffeine; Calcium; Gallopamil; Male; Membranes; Methoxamine; Muscle Relaxation; Muscle, Smooth, Vascular; Rats; Rats, Inbred Strains; Verapamil | 1982 |
Effect of inotropic agents on the calcium binding to isolated cardiac sarcolemma.
Topics: Animals; Caffeine; Calcium; Cations, Divalent; Cations, Monovalent; Dogs; Kinetics; Lanthanum; Myocardium; Neuraminidase; Ouabain; Sarcolemma; Verapamil | 1980 |
Caffeine reversal of length-dependent changes in myocardial contractile state in the cat.
Topics: Animals; Caffeine; Calcium; Cats; Dose-Response Relationship, Drug; Manganese; Myocardial Contraction; Theophylline; Time Factors; Verapamil | 1980 |
[Ca2+]i-dependent membrane currents in guinea-pig ventricular cells in the absence of Na/Ca exchange.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Carrier Proteins; Cations; Cell Membrane; Chloride Channels; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Membrane Potentials; Myocardial Contraction; Myocardium; Patch-Clamp Techniques; Sodium; Sodium-Calcium Exchanger; Verapamil | 1995 |
Leukotriene C4-stimulated contractions in bullfrog lung are affected by cold acclimation and calcium antagonists.
Topics: Acclimatization; Animals; Caffeine; Calcium Channel Blockers; Calcium-Transporting ATPases; Cold Temperature; Contracture; Egtazic Acid; Eicosapentaenoic Acid; Female; Hot Temperature; Leukotriene C4; Lung; Male; Nicardipine; Nifedipine; Nitrendipine; Rana catesbeiana; SRS-A; Terpenes; Thapsigargin; Verapamil | 1995 |
Sodium/calcium exchange in rat cortical astrocytes.
Topics: Animals; Animals, Newborn; Astrocytes; Caffeine; Calcium; Calcium-Transporting ATPases; Carrier Proteins; Cells, Cultured; Cerebral Cortex; Cytosol; DNA, Complementary; Ion Transport; Microscopy, Fluorescence; Ouabain; Rats; RNA; RNA, Messenger; Ryanodine; Sodium; Terpenes; Thapsigargin; Verapamil | 1994 |
Calcium waves in dissociated retinal glial (Müller) cells are evoked by release of calcium from intracellular stores.
Topics: Animals; Caffeine; Calcium; Fura-2; Neuroglia; Potassium; Retina; Ryanodine; Urodela; Verapamil | 1995 |
The effect of calcium channel antagonists and BAY K 8644 on calcium fluxes of malignant hyperpyrexia-susceptible muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Diltiazem; Halothane; Malignant Hyperthermia; Muscle Contraction; Muscles; Nifedipine; Potassium Chloride; Sarcoplasmic Reticulum; Swine; Verapamil | 1993 |
Effects of verapamil, sodium nitroprusside, tetrodotoxin and caffeine on the electrical transmural stimulation induced contraction in the reticular groove smooth muscle of adult cattle.
Topics: Animals; Caffeine; Cattle; Electric Stimulation; Muscle Contraction; Muscle, Smooth; Nitroprusside; Reticulum; Tetrodotoxin; Verapamil | 1994 |
Effects of different agents on the contractile response elicited by extracellular calcium after depletion of internal calcium stores in rat isolated aorta.
Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Extracellular Space; In Vitro Techniques; Intracellular Fluid; Kinetics; Lanthanum; Magnesium; Male; Muscle Contraction; Muscle Tonus; Muscle, Smooth, Vascular; Norepinephrine; Rats; Rats, Wistar; Temperature; Verapamil | 1993 |
Effects of alkylxanthines on contractility of diaphragm fibres isolated from normal and sensitized guinea-pigs.
Topics: Adenosine; Animals; Bronchodilator Agents; Caffeine; Calcium; Culture Media; Dantrolene; Diaphragm; Electric Stimulation; Extracellular Space; Female; Guinea Pigs; Immunization; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Serum Albumin, Bovine; Theobromine; Theophylline; Verapamil; Xanthines | 1993 |
Doxorubicin-induced changes in intracellular Ca2+ transients observed in cardiac myocytes isolated from guinea-pig heart.
Topics: Animals; Caffeine; Calcium Channels; Calcium Chloride; Doxorubicin; Female; Fura-2; Guinea Pigs; Heart; In Vitro Techniques; Isoproterenol; Male; Myocardium; Ryanodine; Sarcoplasmic Reticulum; Spectrometry, Fluorescence; Verapamil | 1994 |
The effects of phorbol 12,13-diacetate on responses of guinea-pig isolated trachea to methylxanthines, isoprenaline and ryanodine.
Topics: Animals; Caffeine; Calcium Chloride; Cold Temperature; Drug Interactions; Female; Guinea Pigs; Histamine; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle Spasticity; Muscle, Smooth; Phorbol Esters; Potassium; Ryanodine; Theophylline; Trachea; Verapamil; Xanthines | 1994 |
Mechanisms of action of enflurane on vascular smooth muscle. Comparison of rabbit aorta and femoral artery.
Topics: Animals; Aorta, Thoracic; Caffeine; Calcium; Endothelium, Vascular; Enflurane; Femoral Artery; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Ryanodine; Sarcoplasmic Reticulum; Verapamil | 1994 |
Effects of vanadate on responses of guinea-pig isolated trachea to spasmogens.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Cell Membrane; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Parasympathomimetics; Potassium Chloride; Serotonin; Trachea; Vanadates; Verapamil | 1993 |
Contractile arrest increases sarcoplasmic reticulum calcium uptake and SERCA2 gene expression in cultured neonatal rat heart cells.
Topics: Animals; Animals, Newborn; Caffeine; Calcium; Calcium-Transporting ATPases; Carrier Proteins; Gene Expression Regulation; Major Histocompatibility Complex; Myocardial Contraction; Myocardium; Rats; RNA, Messenger; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Verapamil | 1994 |
Ryanodine-induced contraction in femoral artery from spontaneously hypertensive rats.
Topics: Animals; Caffeine; Calcium Chloride; Femoral Artery; Male; Muscle Contraction; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ryanodine; Verapamil | 1994 |
Calcium-antagonistic effects of carbamazepine in epilepsies and affective psychoses.
Topics: Animals; Caffeine; Calcium Channel Blockers; Carbamazepine; Epilepsy; Guinea Pigs; Hippocampus; In Vitro Techniques; Magnesium; Membrane Potentials; Mood Disorders; Neurons; Penicillins; Verapamil | 1993 |
Electrical and mechanical alternans in canine myocardium in vivo. Dependence on intracellular calcium cycling.
Topics: Action Potentials; Animals; Biomechanical Phenomena; Caffeine; Calcium; Cold Temperature; Dogs; Electrocardiography; Electrophysiology; Female; Heart; Intracellular Fluid; Male; Myocardium; Ventricular Pressure; Verapamil | 1993 |
An intoxication involving BRON and verapamil.
Topics: Adult; Caffeine; Chlorpheniramine; Codeine; Drug Combinations; Ephedrine; Humans; Male; Suicide; Verapamil | 1993 |
Effect of extracellular ions and modulators of calcium transport on survival of tert-butyl hydroperoxide exposed cardiac myocytes.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cell Size; Cell Survival; Deferoxamine; Diacetyl; Heart; Lipid Peroxidation; Male; Myocardium; Nifedipine; Oxidants; Peroxides; Propyl Gallate; Rats; Rats, Sprague-Dawley; Sodium; tert-Butylhydroperoxide; Verapamil | 1993 |
Chemotaxis of newt eosinophils: calcium regulation of chemotactic response.
Topics: Amino Acid Sequence; Animals; Caffeine; Calcium; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Chromatography, Gel; Cobalt; Egtazic Acid; Eosinophils; Fluorescent Dyes; Fura-2; In Vitro Techniques; Ionomycin; Molecular Sequence Data; Neomycin; Salamandridae; Verapamil | 1993 |
Acute hypoxia increases cytosolic calcium in cultured pulmonary arterial myocytes.
Topics: Acute Disease; Animals; Caffeine; Calcium; Calcium Channels; Calcium-Transporting ATPases; Cells, Cultured; Cytosol; Fura-2; Hypoxia; Male; Microscopy, Fluorescence; Muscle, Smooth, Vascular; Nifedipine; Oxygen; Pulmonary Artery; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Terpenes; Thapsigargin; Verapamil | 1993 |
Role of Na(+)-Ca2+ exchange in the regulation of vascular smooth muscle tension.
Topics: Animals; Caffeine; Calcium; Carrier Proteins; Dose-Response Relationship, Drug; Female; Hydrogen-Ion Concentration; Intracellular Membranes; Isometric Contraction; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nerve Endings; Ouabain; Phentolamine; Prazosin; Rabbits; Sarcolemma; Sodium; Sodium-Calcium Exchanger; Sodium-Potassium-Exchanging ATPase; Vascular Resistance; Verapamil | 1993 |
Modulation of the platelet-derived-growth-factor-induced calcium signal by extracellular/intracellular pH in Syrian hamster embryo cells. Implications for the role of calcium in mitogenic signalling.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Division; Cells, Cultured; Cricetinae; Extracellular Space; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Intracellular Fluid; Mesocricetus; Mitogens; omega-Conotoxins; Peptides; Phosphorylation; Platelet-Derived Growth Factor; Receptors, Cytoplasmic and Nuclear; Receptors, Platelet-Derived Growth Factor; Tyrosine; Verapamil | 1995 |
Mechanisms of action of isoflurane on contraction of rabbit conduit artery.
Topics: Animals; Aorta; Caffeine; Calcium; Endothelium, Vascular; Femoral Artery; Isoflurane; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Rabbits; Vasoconstriction; Verapamil | 1996 |
Depletion and refilling of acetylcholine- and caffeine-sensitive Ca++ stores in tracheal myocytes.
Topics: Acetylcholine; Animals; Caffeine; Calcium; In Vitro Techniques; Indoles; Male; Muscle, Smooth; Swine; Terpenes; Thapsigargin; Trachea; Verapamil | 1996 |
[Mechanism of action of befol on calcium metabolism in cardiomyocytes using the fluorescent probe fura-2].
Topics: Amiodarone; Animals; Benzamides; Caffeine; Calcium; Fura-2; Heart; In Vitro Techniques; Ion Transport; Morpholines; Myocardium; Rats; Verapamil | 1996 |
Effects of Mg2+ on Ca2+ waves and Ca2+ transients of rat ventricular myocytes.
Topics: Animals; Anti-Arrhythmia Agents; Caffeine; Calcium; Cells, Cultured; Fluorescent Dyes; Heart Ventricles; Indoles; Ion Transport; Magnesium; Male; Phosphodiesterase Inhibitors; Rats; Rats, Wistar; Verapamil | 1996 |
Possible mechanism of the potent vasoconstrictor actions of ryanodine on femoral arteries from spontaneously hypertensive rats.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Femoral Artery; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Nifedipine; Phosphodiesterase Inhibitors; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ryanodine; Sarcoplasmic Reticulum; Verapamil | 1996 |
Oscillations of cytosolic free calcium in bombesin-stimulated HIT-T15 cells.
Topics: Animals; Biological Clocks; Bombesin; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium-Transporting ATPases; Cell Line; Central Nervous System Stimulants; Chelating Agents; Circadian Rhythm; Cresols; Cricetinae; Cytosol; Diazoxide; Egtazic Acid; Fura-2; Glucose; Hydroquinones; Membrane Potentials; Ryanodine; Verapamil | 1996 |
The origin of increased cytoplasmic calcium upon reversal of the Na+/Ca(2+)-exchanger in isolated rat ventricular myocytes.
Topics: Animals; Caffeine; Calcium; Carrier Proteins; Cytoplasm; Heart Ventricles; In Vitro Techniques; Ion Transport; Male; Osmolar Concentration; Potassium; Rats; Rats, Wistar; Ryanodine; Sarcoplasmic Reticulum; Sodium-Calcium Exchanger; Thapsigargin; Verapamil | 1996 |
High carbachol increases the electrically induced [Ca2+]i transient in the single isolated ventricular myocyte of rats.
Topics: Animals; Atropine; Caffeine; Calcium; Carbachol; Electric Stimulation; Heart; In Vitro Techniques; Muscarinic Agonists; Nickel; Pertussis Toxin; Rats; Rats, Sprague-Dawley; Ryanodine; Sodium; Verapamil; Virulence Factors, Bordetella | 1997 |
Tetrandrine inhibits electrically induced [Ca2+]i transient in the isolated single rat cardiomyocyte.
Topics: Alkaloids; Animals; Benzylisoquinolines; Caffeine; Calcium; Calcium Channel Blockers; Diltiazem; Electric Stimulation; Heart; In Vitro Techniques; Potassium Chloride; Rats; Rats, Sprague-Dawley; Ryanodine; Sodium; Thapsigargin; Verapamil | 1997 |
[Ca2+]i oscillations induced by muscarinic stimulation in airway smooth muscle cells: receptor subtypes and correlation with the mechanical activity.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Carbachol; In Vitro Techniques; Isometric Contraction; Male; Muscarinic Agonists; Muscle, Smooth; Rats; Rats, Wistar; Receptors, Muscarinic; Verapamil | 1997 |
Spontaneous and repetitive calcium transients in C2C12 mouse myotubes during in vitro myogenesis.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Adenosine Triphosphate; Animals; Apamin; Caffeine; Calcium; Cell Differentiation; Cell Line; Cytosol; Egtazic Acid; Kinetics; Membrane Potentials; Mice; Microscopy, Confocal; Microscopy, Video; Muscle, Skeletal; Oscillometry; Potassium Chloride; Tetraethylammonium; Tetraethylammonium Compounds; Tetrodotoxin; Verapamil | 1997 |
The energetics of the quiescent heart muscle: high potassium cardioplegic solution and the influence of calcium and hypoxia on the rat heart.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Cardioplegic Solutions; Energy Metabolism; Female; Heart; Hot Temperature; Hypoxia; In Vitro Techniques; Male; Myocardium; Oxygen Consumption; Phosphodiesterase Inhibitors; Physical Stimulation; Potassium; Rats; Rats, Wistar; Verapamil | 1997 |
Twitch potentiation induced by caffeine in the mouse diaphragm depends on external calcium ions in the absence of potassium ions.
Topics: Animals; Bepridil; Caffeine; Calcium; Calcium Channel Blockers; Diaphragm; In Vitro Techniques; Male; Membrane Potentials; Mice; Mice, Inbred Strains; Muscle Contraction; Muscle, Skeletal; Potassium; Verapamil | 1997 |
Pheochromocytoma crisis caused by contemporary ergotamine, caffeine, and nimesulide administration.
Topics: Adrenal Gland Neoplasms; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Caffeine; Drug Combinations; Ergotamine; Humans; Hypertension; Male; Metoprolol; Multiple Organ Failure; Pheochromocytoma; Sulfonamides; Verapamil | 1997 |
Caffeine and ryanodine may act on the plasma membrane of the circular muscle at the flexure region in the guinea-pig colon.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Cell Membrane; Colon; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Ryanodine; Verapamil | 1997 |
Relaxing effects of cyclic GMP and cyclic AMP-enhancing agents on the long-lasting contraction to endothelin-1 in the porcine coronary artery.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Atrial Natriuretic Factor; Caffeine; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Endothelin-1; In Vitro Techniques; Isradipine; Milrinone; Muscle, Smooth, Vascular; Papaverine; Phosphodiesterase Inhibitors; Phosphoric Diester Hydrolases; Purinones; Pyrrolidinones; Rolipram; Swine; Vasoactive Intestinal Peptide; Vasoconstriction; Vasodilation; Verapamil; Vinca Alkaloids | 1998 |
Disruption of six novel yeast genes located on chromosome II reveals one gene essential for vegetative growth and two required for sporulation and conferring hypersensitivity to various chemicals.
Topics: Antifungal Agents; Caffeine; Cations; Chromosomes, Fungal; Cloning, Molecular; DNA Primers; Gene Deletion; Genes, Essential; Genes, Fungal; Phenotype; Polymerase Chain Reaction; Saccharomyces cerevisiae; Spores, Fungal; Transformation, Genetic; Verapamil | 1999 |
Transmural pressure inhibits prorenin processing in juxtaglomerular cell.
Topics: Animals; Caffeine; Calcium Channel Blockers; Cells, Cultured; Colforsin; Enzyme Inhibitors; Enzyme Precursors; Juxtaglomerular Apparatus; Male; Pressure; Rats; Rats, Sprague-Dawley; Renin; Thapsigargin; Verapamil | 1999 |
Mechanisms through which PDGF alters intracellular calcium levels in U-1242 MG human glioma cells.
Topics: Becaplermin; Brain Neoplasms; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Signaling; Calcium-Transporting ATPases; Elapid Venoms; Endoplasmic Reticulum; Enzyme Inhibitors; Flufenamic Acid; Glioma; Humans; Imidazoles; Ion Transport; Masoprocol; Neoplasm Proteins; Nicardipine; Nimodipine; Nitrendipine; omega-Agatoxin IVA; omega-Conotoxin GVIA; omega-Conotoxins; Peptides; Platelet-Derived Growth Factor; Proto-Oncogene Proteins c-sis; Ryanodine; Thapsigargin; Tumor Cells, Cultured; Verapamil | 1999 |
Efficacies of tea components on doxorubicin induced antitumor activity and reversal of multidrug resistance.
Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caffeine; Calcium Channel Blockers; Carcinoma, Ehrlich Tumor; Catechin; Doxorubicin; Drug Resistance, Multiple; Drug Screening Assays, Antitumor; Drug Synergism; Flavonoids; Glutamates; Intracellular Fluid; Leukemia P388; Male; Mice; Neoplasm Transplantation; Phytotherapy; Tea; Theobromine; Verapamil | 2000 |
Prostaglandin F2alpha-induced Ca++ oscillations in human myometrial cells and the role of RU 486.
Topics: Adult; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Dinoprost; Edetic Acid; Female; Fura-2; Hormone Antagonists; Humans; Middle Aged; Mifepristone; Myometrium; Ryanodine; Up-Regulation; Verapamil | 2000 |
Voltage-independent calcium entry in hypoxic pulmonary vasoconstriction of intrapulmonary arteries of the rat.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Chelating Agents; Diltiazem; Dinucleoside Phosphates; Egtazic Acid; Electric Stimulation; Enzyme Inhibitors; Hypoxia; Imidazoles; In Vitro Techniques; Ion Channel Gating; Lanthanum; Male; Membrane Potentials; Nifedipine; Phosphodiesterase Inhibitors; Pulmonary Artery; Pulmonary Circulation; Rats; Rats, Wistar; Ryanodine; Thapsigargin; Vasoconstriction; Verapamil | 2000 |
Abnormalities in Ca(i)handling in myocytes that survive in the infarcted heart are not just due to alterations in repolarization.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Central Nervous System Stimulants; Chelating Agents; Dogs; Electrophysiology; Fluorescent Dyes; Fura-2; Ions; Myocardial Infarction; Myocardium; Nickel; Ryanodine; Sodium; Sodium-Calcium Exchanger; Time Factors; Verapamil | 2000 |
Relationship between extra and intracellular sources of calcium and the contractile effect of thiopental in rat aorta.
Topics: Animals; Aorta; Caffeine; Calcium; Calcium Channel Blockers; Diltiazem; Endothelium, Vascular; Hypnotics and Sedatives; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascular; Phenylephrine; Rats; Rats, Wistar; Thiopental; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Verapamil | 2001 |
Modulation of gonadotropin II release by K+ channel blockers in goldfish gonadotropes: a novel stimulatory action of 4-aminopyridine.
Topics: 4-Aminopyridine; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Fluorescent Dyes; Fura-2; Goldfish; Gonadotropins, Pituitary; Phosphodiesterase Inhibitors; Pituitary Gland; Potassium Channel Blockers; Tetraethylammonium; Verapamil | 2001 |
Influence of propranolol, enalaprilat, verapamil, and caffeine on adenosine A(2A)-receptor-mediated coronary vasodilation.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Caffeine; Calcium Channel Blockers; Coronary Circulation; Cyclohexanecarboxylic Acids; Disease Models, Animal; Dogs; Enalaprilat; Hemodynamics; Phosphodiesterase Inhibitors; Propranolol; Purines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Vasodilation; Verapamil | 2002 |
Caffeine-induced contracture in oesophageal striated muscle of normotensive and hypertensive rats.
Topics: Animals; Blood Pressure; Body Weight; Caffeine; Calcium; Calcium Channel Blockers; Central Nervous System Stimulants; Esophagus; Hypertension; In Vitro Techniques; Membrane Potentials; Muscle Contraction; Muscle, Skeletal; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ryanodine; Verapamil | 2003 |
L-type Ca2+ channel antagonists block voltage-dependent Ca2+ channels in identified leech neurons.
Topics: Animals; Caffeine; Calcium Channel Blockers; Calcium Channels, L-Type; Diltiazem; Gallopamil; Leeches; Membrane Potentials; Neurons; Nifedipine; Phosphodiesterase Inhibitors; Verapamil | 2004 |
The role of Ca2+ in the contractility of rabbit small intestine in vitro.
Topics: Acetylcholine; Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Duodenum; Ileum; In Vitro Techniques; Indoles; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Nifedipine; Potassium Chloride; Rabbits; Thapsigargin; Verapamil | 2004 |
The role of nitric oxide on contractile impairment during endotoxemia in rat diaphragm muscle.
Topics: Animals; Caffeine; Diaphragm; Endotoxemia; Enzyme Inhibitors; Guanidines; In Vitro Techniques; Indazoles; Lipopolysaccharides; Male; Muscle Contraction; Neuromuscular Nondepolarizing Agents; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxadiazoles; Quinoxalines; Rats; Rats, Wistar; Ryanodine; Tubocurarine; Vasodilator Agents; Verapamil | 2004 |
Sites and modes of action of proctolin and the FLP F2 on lobster cardiac muscle.
Topics: Animals; Cadmium; Caffeine; Calcium; Calcium Channel Blockers; Calcium Channels; Fluorescence; Membrane Potentials; Microelectrodes; Myocardial Contraction; Myocardium; Nephropidae; Neuropeptides; Nifedipine; Oligopeptides; Ryanodine; Sarcoplasmic Reticulum; Verapamil | 2005 |
Effects of caffeine, verapamil, lithium, and KB-R7943 on mechanics and energetics of rat myocardial bigeminies.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Electric Stimulation; Heart; In Vitro Techniques; Intracellular Membranes; Lithium Chloride; Myocardial Contraction; Pressure; Rats; Rats, Wistar; Sodium-Calcium Exchanger; Thermogenesis; Thiourea; Verapamil | 2006 |
Calcium gradients in conifer pollen tubes; dynamic properties differ from those seen in angiosperms.
Topics: Caffeine; Calcium; Calcium Channel Blockers; Calcium Signaling; Gadolinium; Germination; Lanthanum; Magnoliopsida; Picea; Pollen; Verapamil | 2005 |
Reduction of perifusate magnesium alters inotropic response of papillary muscle to ion channel modulators.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Cardiotonic Agents; Female; Humans; Ion Channels; Magnesium; Myocardial Contraction; Myocytes, Cardiac; Ouabain; Papillary Muscles; Perfusion; Rats; Rats, Sprague-Dawley; Ryanodine; Verapamil | 2005 |
Functional properties of human embryonic stem cell-derived cardiomyocytes: intracellular Ca2+ handling and the role of sarcoplasmic reticulum in the contraction.
Topics: Animals; Caffeine; Calcium; Dose-Response Relationship, Drug; Embryo, Mammalian; Heart Conduction System; Humans; Mice; Myocardial Contraction; Myocytes, Cardiac; Ryanodine; Sarcoplasmic Reticulum; Stem Cells; Thapsigargin; Verapamil | 2006 |
Warming and response to contractile agents in calf cardiac vein: role of the Ca2+, KCa2+, and Na+ ion channel blockers.
Topics: Animals; Caffeine; Calcium Channel Blockers; Carbachol; Cattle; Coronary Vessels; Egtazic Acid; Flecainide; Hot Temperature; In Vitro Techniques; Potassium Channel Blockers; Quaternary Ammonium Compounds; Serotonin; Sodium Channel Blockers; Vasoconstriction; Verapamil | 2005 |
Hemorheological efficiency of drugs, targeting on intracellular phosphodiesterase activity: in vitro study.
Topics: 1-Methyl-3-isobutylxanthine; Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids | 2007 |
Effects of verapamil and gadolinium on caffeine-induced contractures and calcium fluxes in frog slow skeletal muscle fibers.
Topics: Animals; Anura; Caffeine; Calcium; Contracture; Gadolinium; Ion Transport; Models, Biological; Muscle Fibers, Slow-Twitch; Muscle, Skeletal; Verapamil | 2008 |
Aberration of L-type calcium channel in cardiac myocytes is one of the mechanisms of arrhythmia induced by cerebral ischemia.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Brain Ischemia; Caffeine; Calcium; Calcium Channels, L-Type; Cerebral Infarction; Electrocardiography; Gene Expression Regulation; Homeostasis; Infarction, Middle Cerebral Artery; Intracellular Space; Ion Channel Gating; Kinetics; Male; Myocardium; Myocytes, Cardiac; Potassium Chloride; Protein Subunits; Rats; Rats, Wistar; Verapamil | 2008 |
In vitro antioxidant properties of pentoxifylline and vinpocetine in a rheological model.
Topics: Adult; Blood Viscosity; Caffeine; Calcimycin; Calcium; Egtazic Acid; Erythrocyte Aggregation; Free Radical Scavengers; Hemorheology; Humans; Male; Nifedipine; Papaverine; Pentoxifylline; Phosphodiesterase Inhibitors; Verapamil; Vinca Alkaloids | 2008 |
Cardiac myocyte excitation by ultrashort high-field pulses.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium Signaling; Cells, Cultured; Electric Stimulation; Extracellular Space; Membrane Potentials; Myocytes, Cardiac; Rats; Rats, Sprague-Dawley; Ryanodine; Sodium Channel Blockers; Tetrodotoxin; Thapsigargin; Thiourea; Verapamil | 2009 |
Blood pressure-lowering and vascular modulator effects of Acorus calamus extract are mediated through multiple pathways.
Topics: Acetylcholine; Acorus; Animals; Aorta, Thoracic; Atropine; Blood Pressure; Caffeine; Dose-Response Relationship, Drug; Egtazic Acid; Endothelium, Vascular; Indomethacin; Inhibitory Concentration 50; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Phenylephrine; Plant Extracts; Plant Roots; Potassium Chloride; Rats; Rats, Sprague-Dawley; Reference Standards; Ryanodine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Verapamil | 2009 |
The impact of extracellular and intracellular Ca2+ on ethanol-induced smooth muscle contraction.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Calcium-Transporting ATPases; Dose-Response Relationship, Drug; Drug Interactions; Ethanol; Female; Gastric Fundus; Indoles; Isometric Contraction; Male; Mice; Muscle Contraction; Muscle, Smooth; Nifedipine; Ruthenium Red; Ryanodine; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Verapamil | 2009 |
Differential contractile impairment of fast- and slow-twitch skeletal muscles in a rat model of doxorubicin-induced congestive heart failure.
Topics: Action Potentials; Animals; Caffeine; Disease Models, Animal; Doxorubicin; Heart Failure; Male; Membrane Potentials; Miniature Postsynaptic Potentials; Muscle Contraction; Muscle, Skeletal; Potassium; Rats; Rats, Wistar; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Verapamil | 2009 |
Calcium transport and homeostasis in gill cells of a freshwater crab Dilocarcinus pagei.
Topics: Amiloride; Animals; Biological Transport; Brachyura; Caffeine; Calcium; Calcium Channel Blockers; Cells, Cultured; Epithelial Cells; Gills; Homeostasis; Kinetics; Nifedipine; Ouabain; Sodium; Sodium-Calcium Exchanger; Thiourea; Vanadates; Verapamil | 2010 |
Participation of L-type calcium channels in ethanol-induced behavioral stimulation and motor incoordination: effects of diltiazem and verapamil.
Topics: Analysis of Variance; Animals; Ataxia; Behavior, Animal; Caffeine; Calcium Channel Blockers; Calcium Channels, L-Type; Central Nervous System Stimulants; Cocaine; Diltiazem; Dose-Response Relationship, Drug; Ethanol; Male; Mice; Motor Activity; Rotarod Performance Test; Verapamil | 2010 |
Up-regulation of P-glycoprotein reduces intracellular accumulation of beta amyloid: investigation of P-glycoprotein as a novel therapeutic target for Alzheimer's disease.
Topics: Alzheimer Disease; Amyloid beta-Peptides; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeine; Cell Line; Central Nervous System Agents; Dexamethasone; Estradiol; Humans; Pentylenetetrazole; Phloroglucinol; Rifampin; Staining and Labeling; Terpenes; Up-Regulation; Verapamil | 2011 |
Exposure of LS-180 cells to drugs of diverse physicochemical and therapeutic properties up-regulates P-glycoprotein expression and activity.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Caffeine; Cell Line, Tumor; Dexamethasone; Dose-Response Relationship, Drug; Drug Interactions; Estradiol; Gene Expression; Humans; Pentylenetetrazole; Pharmaceutical Preparations; Phloroglucinol; Rhodamine 123; Rifampin; Stimulation, Chemical; Terpenes; Up-Regulation; Verapamil | 2011 |
Inhibitory effects of sertraline in rat isolated perfused kidneys and in isolated ring preparations of rat arteries.
Topics: Animals; Caffeine; Calcium; Calcium Channel Blockers; Glomerular Filtration Rate; Kidney; Male; Mesentery; Muscle Contraction; Muscle, Smooth, Vascular; Parasympatholytics; Phenylephrine; Pressure; Rats; Rats, Wistar; Renal Artery; Sarcolemma; Sertraline; Thapsigargin; Urination; Vascular Resistance; Vasoconstriction; Vasodilator Agents; Verapamil | 2011 |
Role of calcium in contractile responses of calf cardiac vein during cooling.
Topics: Animals; Caffeine; Calcium; Carbachol; Cattle; Cold Temperature; Coronary Vessels; Egtazic Acid; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Serotonin; Veins; Verapamil | 2011 |
[Ca2+]i oscillations in ASM: relationship with persistent airflow obstruction in asthma.
Topics: Adult; Aged; Asthma; Biopsy; Caffeine; Calcium Signaling; Case-Control Studies; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Muscle, Smooth; Nitrendipine; Pulmonary Disease, Chronic Obstructive; Respiratory Muscles; Severity of Illness Index; Verapamil; Vital Capacity | 2014 |
Characterization of cadmium plasma membrane transport in gills of a mangrove crab Ucides cordatus.
Topics: Animals; Biological Transport; Brachyura; Cadmium; Caffeine; Calcium; Calcium Channel Blockers; Cell Membrane; Cell Survival; Chelating Agents; Egtazic Acid; Fluorescence; Fluorescent Dyes; Gills; Ion Transport; Nimodipine; Vanadates; Verapamil; Water Pollutants, Chemical | 2014 |
Sex differences in liver toxicity-do female and male human primary hepatocytes react differently to toxicants in vitro?
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; Calcium; Cell Membrane Permeability; Cell Survival; Cells, Cultured; Chlorpromazine; Diclofenac; Dose-Response Relationship, Drug; Endoplasmic Reticulum; Female; Hepatocytes; Humans; Male; Membrane Potential, Mitochondrial; Omeprazole; Primary Cell Culture; Sex Characteristics; Verapamil | 2015 |