verapamil and buspirone

verapamil has been researched along with buspirone in 22 studies

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.55)18.7374
1990's4 (18.18)18.2507
2000's5 (22.73)29.6817
2010's12 (54.55)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Ahman, M; Holmén, AG; Wan, H1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Claxton, CR; Curran, RE; Harradine, PJ; Hutchison, L; Littlewood, P; Martin, IJ1
Sen, S; Sinha, N1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Chase, TN; Gillespie, M; Naber, D; Weinberger, DR1
Janowsky, DS; Overstreet, DH; Rezvani, AH1
Berger, M; Roed, I; von Wegerer, J; Walden, J1
Kivistö, KT; Lamberg, TS; Neuvonen, PJ1
Grubb, MF; Humphreys, WG; Josephs, JL1
Bellavance, E; Bourg, S; Duan, J; Garneau, M; Ribadeneira, MD; Rioux, N1
Kostiainen, R; Kotiaho, T; Miikkulainen, V; Ritala, M; Ruokolainen, M; Sikanen, T1
Franssen, MCR; Kostiainen, R; Miikkulainen, V; Nielen, MWF; Ritala, M; van Geenen, FAMG; Zuilhof, H1

Reviews

1 review(s) available for verapamil and buspirone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for verapamil and buspirone

ArticleYear
Failure of buspirone and verapamil to improve spasmodic torticollis.
    The Journal of neuropsychiatry and clinical neurosciences, 1992,Winter, Volume: 4, Issue:1

    Topics: Adult; Buspirone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Neurologic Examination; Torticollis; Verapamil

1992
Effects of verapamil and diltiazem on the pharmacokinetics and pharmacodynamics of buspirone.
    Clinical pharmacology and therapeutics, 1998, Volume: 63, Issue:6

    Topics: Adult; Buspirone; Calcium Channel Blockers; Cross-Over Studies; Diltiazem; Female; Humans; Male; Reference Values; Serotonin Receptor Agonists; Verapamil

1998

Other Studies

19 other study(ies) available for verapamil and buspirone

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Relationship between brain tissue partitioning and microemulsion retention factors of CNS drugs.
    Journal of medicinal chemistry, 2009, Mar-26, Volume: 52, Issue:6

    Topics: Brain; Central Nervous System; Chromatography, Liquid; Emulsions; Mass Spectrometry

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Control and measurement of plasma pH in equilibrium dialysis: influence on drug plasma protein binding.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Blood Proteins; Buffers; Carbon Dioxide; Chemical Phenomena; Dialysis; Dogs; Drug Evaluation, Preclinical; Humans; Hydrogen-Ion Concentration; Macaca fascicularis; Mice; Osmolar Concentration; Pharmaceutical Preparations; Protein Binding; Rats; Reproducibility of Results

2011
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Drug-induced reductions in ethanol intake in alcohol preferring and Fawn-Hooded rats.
    Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, 1991, Volume: 1

    Topics: Alcohol Drinking; Alcoholism; Animals; Buspirone; Drinking Behavior; Ethanol; Feeding Behavior; Fluoxetine; Male; Pindolol; Piperazines; Rats; Rats, Inbred Strains; Rats, Wistar; Scopolamine; Self Administration; Serotonin Receptor Agonists; Species Specificity; Verapamil

1991
Effects of the serotonin-1A agonists buspirone and ipsapirone on field potentials in the hippocampus slice: comparison with carbamzepine and verapamil.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1995, Volume: 5, Issue:1

    Topics: Animals; Buspirone; Carbamazepine; Dose-Response Relationship, Drug; Evoked Potentials; Guinea Pigs; Hippocampus; Magnesium; Pyrimidines; Serotonin Receptor Agonists; Verapamil

1995
A semi-automated method for the integrated evaluation of half-life and metabolic soft spots of discovery compounds.
    Bioanalysis, 2012, Volume: 4, Issue:14

    Topics: Animals; Automation; Biotransformation; Buspirone; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Dogs; Drug Evaluation, Preclinical; Half-Life; Humans; Mianserin; Microsomes, Liver; Mirtazapine; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Verapamil

2012
Assessment of CYP3A-mediated drug-drug interaction potential for victim drugs using an in vivo rat model.
    Biopharmaceutics & drug disposition, 2013, Volume: 34, Issue:7

    Topics: Animals; Buspirone; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Ketoconazole; Male; Microsomes, Liver; Rats; Rats, Wistar; Ritonavir; Verapamil

2013
TiO
    Analytical chemistry, 2017, 11-07, Volume: 89, Issue:21

    Topics: Amodiaquine; Buspirone; Catalysis; Oxidation-Reduction; Photochemistry; Spectrometry, Mass, Electrospray Ionization; Titanium; Ultraviolet Rays; Verapamil

2017
TiO
    Journal of the American Society for Mass Spectrometry, 2019, Volume: 30, Issue:4

    Topics: Acetamides; Aminophenols; Androgen Antagonists; Androgens; Anilides; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Buspirone; Catalysis; Equipment Design; Humans; Laser Therapy; Lasers; Light; Oxidation-Reduction; Pharmaceutical Preparations; Spectrometry, Mass, Electrospray Ionization; Titanium; Verapamil

2019