verapamil and bumetanide

verapamil has been researched along with bumetanide in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19903 (12.50)18.7374
1990's3 (12.50)18.2507
2000's7 (29.17)29.6817
2010's11 (45.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Alvarez-Pedraglio, A; Colmenarejo, G; Lavandera, JL1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Benet, LZ; Brouwer, KL; Chu, X; Dahlin, A; Evers, R; Fischer, V; Giacomini, KM; Hillgren, KM; Hoffmaster, KA; Huang, SM; Ishikawa, T; Keppler, D; Kim, RB; Lee, CA; Niemi, M; Polli, JW; Sugiyama, Y; Swaan, PW; Tweedie, DJ; Ware, JA; Wright, SH; Yee, SW; Zamek-Gliszczynski, MJ; Zhang, L1
Afshari, CA; Eschenberg, M; Hamadeh, HK; Lee, PH; Lightfoot-Dunn, R; Morgan, RE; Qualls, CW; Ramachandran, B; Trauner, M; van Staden, CJ1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bellman, K; Knegtel, RM; Settimo, L1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Kurtz, A; Scholz, H1
DeSantiago, J; Espinosa-Tanguma, R; Rasgado-Flores, H1
Koek, L; Melvin, JE; Zhang, GH1
Boero, R; Deabate, MC; Forneris, G; Guarena, C; Piccoli, G; Quarello, F; Rosati, C1
Bourgain, RH; Braquet, P; Deby, C; Deby-Dupont, G; Garay, RP; Pincemail, J1
Lowenthal, DT1
Denaro, MG; Faggio, C; Lionetto, MG; Trischitta, F1
Ameloot, M; Balut, C; Jans, F; Steels, P; Wouters, P1
Perry, MS; Turner, AL1

Reviews

3 review(s) available for verapamil and bumetanide

ArticleYear
Membrane transporters in drug development.
    Nature reviews. Drug discovery, 2010, Volume: 9, Issue:3

    Topics: Animals; Computer Simulation; Decision Trees; Drug Approval; Drug Discovery; Drug Evaluation, Preclinical; Drug Interactions; Humans; Membrane Transport Proteins; Mice; Mice, Knockout; Prescription Drugs

2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Outside the box: Medications worth considering when traditional antiepileptic drugs have failed.
    Seizure, 2017, Volume: 50

    Topics: Amantadine; Anticonvulsants; Bumetanide; Central Nervous System Stimulants; Epilepsy; Humans; Imipramine; Lidocaine; Treatment Failure; Verapamil

2017

Other Studies

21 other study(ies) available for verapamil and bumetanide

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Cheminformatic models to predict binding affinities to human serum albumin.
    Journal of medicinal chemistry, 2001, Dec-06, Volume: 44, Issue:25

    Topics: Adrenergic beta-Antagonists; Antidepressive Agents, Tricyclic; Chromatography, Affinity; Cyclooxygenase Inhibitors; Databases, Factual; Humans; Hydrophobic and Hydrophilic Interactions; Penicillins; Pharmaceutical Preparations; Protein Binding; Quantitative Structure-Activity Relationship; Reproducibility of Results; Serum Albumin; Steroids

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2010, Volume: 118, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Cell Line; Cell Membrane; Chemical and Drug Induced Liver Injury; Cytoplasmic Vesicles; Drug Evaluation, Preclinical; Humans; Liver; Rats; Reproducibility of Results; Spodoptera; Transfection; Xenobiotics

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Comparison of the accuracy of experimental and predicted pKa values of basic and acidic compounds.
    Pharmaceutical research, 2014, Volume: 31, Issue:4

    Topics: Chemistry, Pharmaceutical; Forecasting; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Random Allocation

2014
Disparate effects of calcium channel blockers on pressure dependence of renin secretion and flow in the isolated perfused rat kidney.
    Pflugers Archiv : European journal of physiology, 1992, Volume: 421, Issue:2-3

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bumetanide; Calcium Channel Blockers; Glomerular Filtration Rate; In Vitro Techniques; Isoproterenol; Kidney; Nifedipine; Potassium; Rats; Rats, Inbred Strains; Renin; Sodium; Verapamil

1992
Stoichiometry and regulation of the Na-Ca exchanger in barnacle muscle cells.
    Annals of the New York Academy of Sciences, 1991, Volume: 639

    Topics: Animals; Bumetanide; Calcium; Calcium Channels; Carrier Proteins; Chymotrypsin; Kinetics; Membrane Potentials; Muscles; Ouabain; Sodium; Sodium-Calcium Exchanger; Thoracica; Verapamil

1991
A capacitative Ca2+ influx is required for sustained fluid secretion in sublingual mucous acini.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 1

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Bumetanide; Calcium; Calcium Channel Blockers; Chlorides; Electric Conductivity; Kinetics; Male; Mouth Mucosa; Potassium; Rats; Sodium; Sublingual Gland; Verapamil

1991
In vitro effects of verapamil and methoxy-verapamil [D 600] on transmembrane sodium and potassium transport in human erythrocytes.
    Bollettino della Societa italiana di biologia sperimentale, 1985, Jun-30, Volume: 61, Issue:6

    Topics: Biological Transport, Active; Bumetanide; Erythrocytes; Gallopamil; Humans; In Vitro Techniques; Ouabain; Potassium; Sodium; Sodium-Potassium-Exchanging ATPase; Verapamil

1985
Modulation of in vivo generation of prostanoids by drugs affecting membrane ion transport.
    Drugs under experimental and clinical research, 1988, Volume: 14, Issue:2-3

    Topics: 6-Ketoprostaglandin F1 alpha; Animals; Arachidonic Acid; Arachidonic Acids; Blood Pressure; Bumetanide; Diuretics; Ethylmaleimide; Furosemide; Insulin; Male; Models, Biological; Potassium; Prostaglandin-Endoperoxide Synthases; Pyridines; Rabbits; Thromboxane B2; Time Factors; Verapamil

1988
New drugs for hypertension.
    American family physician, 1984, Volume: 29, Issue:5

    Topics: Antihypertensive Agents; Bumetanide; Diltiazem; Dipeptides; Enalapril; Guanabenz; Guanidines; Humans; Indapamide; Labetalol; Nifedipine; Pindolol; Verapamil

1984
Ca++ regulation of paracellular permeability in the middle intestine of the eel, Anguilla anguilla.
    Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology, 2001, Volume: 171, Issue:2

    Topics: Anguilla; Animals; Bumetanide; Calcimycin; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Chelating Agents; Diuretics; Diuretics, Osmotic; Egtazic Acid; Electric Impedance; Gallic Acid; Intestinal Mucosa; Ionophores; Mannitol; Sodium Chloride; Tight Junctions; Verapamil

2001
Investigation of the Ba2+-sensitive NH4+ transport pathways in the apical cell membrane of primary cultured rabbit MTAL cells.
    Nephron. Physiology, 2007, Volume: 106, Issue:3

    Topics: Ammonium Chloride; Animals; Antiporters; Barium; Bee Venoms; Biological Transport; Bumetanide; Calcium Channel Blockers; Cation Transport Proteins; Cell Polarity; Cells, Cultured; Cesium; Hydrogen-Ion Concentration; Kidney Medulla; Loop of Henle; Membrane Potentials; Potassium; Potassium Channel Blockers; Potassium Channels, Inwardly Rectifying; Rabbits; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Potassium-Chloride Symporters; Time Factors; Verapamil

2007