Compounds > verapamil

verapamil and amodiaquine

verapamil has been researched along with amodiaquine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's5 (62.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Freiwald, S; Jiang, Y; Jones, JP; Kaspera, R; Katayama, J; Lee, CA; Smith, E; Totah, RA; Walker, GS1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, L; Fei, J; Mei, Y; Ren, S; Yan, SF; Zeng, J; Zhang, JZ1
Bray, PG; Hawley, SR; Naisbitt, DJ; O'Neill, PM; Park, BK; Ward, SA1
Fidock, DA; Sidhu, AB; Verdier-Pinard, D1
Warhurst, DC1
Kostiainen, R; Kotiaho, T; Miikkulainen, V; Ritala, M; Ruokolainen, M; Sikanen, T1

Other Studies

8 other study(ies) available for verapamil and amodiaquine

ArticleYear
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:5

    Topics: Amiodarone; Astemizole; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Danazol; Drug Discovery; Drug Interactions; Enzyme Inhibitors; Humans; Hydroxylation; In Vitro Techniques; Methylation; Microsomes, Liver; Models, Biological; Molecular Structure; Substrate Specificity; Tandem Mass Spectrometry; Terfenadine

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery and characterization of novel, potent, and selective cytochrome P450 2J2 inhibitors.
    Drug metabolism and disposition: the biological fate of chemicals, 2013, Volume: 41, Issue:1

    Topics: Chromatography, High Pressure Liquid; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Discovery; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Kinetics; Microsomes, Liver; Models, Molecular; Molecular Dynamics Simulation; Substrate Specificity

2013
Manipulation of the N-alkyl substituent in amodiaquine to overcome the verapamil-sensitive chloroquine resistance component.
    Antimicrobial agents and chemotherapy, 1996, Volume: 40, Issue:10

    Topics: Alkylation; Amodiaquine; Animals; Antimalarials; Calcium Channel Blockers; Cell Survival; Chemical Phenomena; Chemistry, Physical; Chloroquine; Drug Resistance; Glutathione; Humans; In Vitro Techniques; Leukocytes; Plasmodium falciparum; Verapamil

1996
Chloroquine resistance in Plasmodium falciparum malaria parasites conferred by pfcrt mutations.
    Science (New York, N.Y.), 2002, Oct-04, Volume: 298, Issue:5591

    Topics: Alleles; Amodiaquine; Animals; Antimalarials; Artemisinins; ATP-Binding Cassette Transporters; Chloroquine; Cloning, Molecular; Drug Resistance; Genes, Protozoan; Haplotypes; Mefloquine; Membrane Proteins; Membrane Transport Proteins; Parasitic Sensitivity Tests; Phenotype; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinine; Sesquiterpenes; Transfection; Verapamil

2002
Polymorphism in the Plasmodium falciparum chloroquine-resistance transporter protein links verapamil enhancement of chloroquine sensitivity with the clinical efficacy of amodiaquine.
    Malaria journal, 2003, Sep-19, Volume: 2

    Topics: Amodiaquine; Animals; Antimalarials; Cell Line; Chloride Channels; Chloroquine; Drug Resistance; Drug Synergism; Hydrophobic and Hydrophilic Interactions; Ion Channels; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins; Transfection; Verapamil

2003
TiO
    Analytical chemistry, 2017, 11-07, Volume: 89, Issue:21

    Topics: Amodiaquine; Buspirone; Catalysis; Oxidation-Reduction; Photochemistry; Spectrometry, Mass, Electrospray Ionization; Titanium; Ultraviolet Rays; Verapamil

2017