verapamil has been researched along with 1,4-dihydropyridine in 42 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (38.10) | 18.7374 |
| 1990's | 15 (35.71) | 18.2507 |
| 2000's | 10 (23.81) | 29.6817 |
| 2010's | 1 (2.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Howlett, SE; Nicholl, PA | 1 |
| Zernig, G | 1 |
| Benterbusch, R; Herberg, FW; Melzer, W; Thieleczek, R | 1 |
| Brocklehurst, KW; Ceña, V; Pollard, HB; Rojas, E | 1 |
| Bittar, EE; Nwoga, J | 1 |
| Glossmann, H; Knaus, HG; Romanin, C; Scheffauer, F; Schindler, HG | 1 |
| Hosey, MM; McMahon, KK; Ptasienski, J | 1 |
| Creba, JA; Karobath, M | 1 |
| Glossmann, H; Goll, A; Moosburger, K; Striessnig, J | 1 |
| Challoner-Hue, L; Steele, TH | 1 |
| Dunn, SM | 1 |
| Florio, T; Grimaldi, M; Landolfi, E; Magri, G; Meucci, O; Schettini, G | 1 |
| Barhanin, J; Henning, R; Lazdunski, M; Lerch, U; Oekonomopulos, R; Qar, J; Romey, G; Urbach, H | 1 |
| Reynolds, IJ; Snowman, AM; Snyder, SH | 1 |
| Barlier, S; Colin, DA; Couraud, F; Dayanithi, G; Kretz-Zaepfel, M; Martin-Moutot, N; Nordmann, JJ | 1 |
| Glossmann, H; Zernig, G | 1 |
| Bolger, GT; Crawley, JN; Paul, SM; Rafferty, MF; Skolnick, P | 1 |
| Giacomini, JC; Giacomini, KM; Nelson, WL; Zobrist, RH | 1 |
| Cavero, I; Spedding, M | 1 |
| Kass, RS; Sanguinetti, MC | 1 |
| Ferry, DR; Gadow, C; Glossmann, H; Goll, A | 1 |
| Kostiuk, PG | 1 |
| Akiyama, Y; Morinaga, Y; Nakagawa, R; Ohishi, K; Ohsumi, K; Sekiyama, T; Suga, Y; Tsuji, T; Tsuruo, T | 1 |
| Lombet, A; Spedding, M | 1 |
| Katina, IE; Lukyanenko, V; Nasledov, GA; Terentyev, DA | 1 |
| Kuniyasu, A; Nakayama, H | 1 |
| Barakat, L; Boquet, G; Djiane, J; Dufy, B; Paly, J | 1 |
| Garrigos, M; Orlowski, S; Pascaud, C | 1 |
| Kanaya, N; Kawana, S; Kimura, H; Matsumoto, M; Miyamoto, A; Namiki, A; Ohshika, H; Tsuchida, H | 1 |
| Atchison, WD; Hewett, SJ; Xu, YF | 1 |
| Gao, X; Gillman, MW; Goldman, L; Hertzmark, E; McLaughlin, TJ; Ross-Degnan, D; Soumerai, SB; Spiegelman, D | 1 |
| Lévy, S | 1 |
| Bidet, M; Martial, S; Martin, D; Melendez, E; Namorado, MD; Poujeol, C; Poujeol, P; Reyes, JL; Sanchez, E; Tauc, M; Valencia, L | 1 |
| El Bardai, S; Hamaide, MC; Lyoussi, B; Morel, N; Quetin-Leclercq, J; Wibo, M | 1 |
| Hoda, JC; Huber, IG; Sinnegger-Brauns, MJ; Striessnig, J; Walter-Bastl, D; Wappl-Kornherr, E | 1 |
| Handler, J | 1 |
| Logan, A | 1 |
| Amini, M; Azizi, E; Bazargan, L; Fouladdel, S; Ghaffari, SM; Shafiee, A | 1 |
| Holstege, C; Winchester, DE | 1 |
| Berenshteĭn, NV; Burmistrova, LF; Iskenderov, BG; Lokhina, TV | 1 |
| Engi, H | 1 |
| Bergmann, I; Deters, M; Enden, G; Hentschel, H; Kutz, S; Liebetrau, G; Plenert, B; Prasa, D | 1 |
4 review(s) available for verapamil and 1,4-dihydropyridine
| Article | Year |
|---|---|
"Calcium antagonists": a class of drugs with a bright future. Part II. Determination of basic pharmacological properties.
Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Electrophysiology; Heart Rate; Ion Channels; Lanthanum; Methods; Muscle, Smooth; Myocardial Contraction; Nifedipine; Potassium; Pyridines; Receptors, Adrenergic, alpha; Stereoisomerism; Verapamil | 1984 |
[Calcium ion channels in the cell membrane].
Topics: Animals; Brachyura; Calcium; Cations, Divalent; Cations, Monovalent; Cattle; Decapodiformes; Dihydropyridines; Fluorides; In Vitro Techniques; Ion Channels; Kinetics; Membrane Potentials; Mice; Mollusca; Neurons; Organ Specificity; Pyridines; Rats; Species Specificity; Verapamil | 1984 |
Identification of binding sites for calcium channel antagonists.
Topics: Affinity Labels; Benzazepines; Binding Sites; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Diltiazem; Drug Interactions; Humans; Muscle, Skeletal; Thiazepines; Verapamil | 1996 |
Pharmacologic management of atrial fibrillation: current therapeutic strategies.
Topics: Adrenergic beta-Antagonists; Anti-Arrhythmia Agents; Atrial Fibrillation; Calcium Channel Blockers; Chronic Disease; Digoxin; Dihydropyridines; Drug Administration Routes; Electrocardiography; Embolism; Heart Rate; Humans; Practice Guidelines as Topic; Prognosis; Propranolol; Secondary Prevention; Tachycardia, Paroxysmal; Verapamil | 2001 |
2 trial(s) available for verapamil and 1,4-dihydropyridine
| Article | Year |
|---|---|
BENEDICT in the treatment of hypertension.
Topics: Albuminuria; Angiotensin-Converting Enzyme Inhibitors; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Creatinine; Diabetes Mellitus, Type 2; Dihydropyridines; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypertension; Indoles; Treatment Outcome; Verapamil | 2005 |
[Hypotensive efficacy and tolerability of combination of dihydropyridine and non-dihydropyridine calcium antagonists in the treatment of patients with arterial hypertension].
Topics: Adult; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dihydropyridines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypercholesterolemia; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Nifedipine; Obesity; Treatment Outcome; Verapamil | 2007 |
36 other study(ies) available for verapamil and 1,4-dihydropyridine
| Article | Year |
|---|---|
Density of 1,4-dihydropyridine receptors decreases in the hearts of aging hamsters.
Topics: Aging; Allosteric Site; Animals; Calcium Channels; Cricetinae; Dihydropyridines; Diltiazem; In Vitro Techniques; Kinetics; Male; Myocardium; Nifedipine; Verapamil | 1992 |
Photoaffinity labeling of the partially purified mitochondrial phenylalkylamine calcium antagonist receptor.
Topics: Affinity Labels; Azides; Calcium Channel Blockers; Calcium Channels; Dihydropyridines; Electrophoresis, Polyacrylamide Gel; Mitochondria; Verapamil | 1992 |
Excitation-contraction coupling in a pre-vertebrate twitch muscle: the myotomes of Branchiostoma lanceolatum.
Topics: Animals; Blotting, Western; Calcium; Calcium-Transporting ATPases; Cell Membrane; Cell Movement; Chordata, Nonvertebrate; Dihydropyridines; Membrane Potentials; Microsomes; Muscle Contraction; Nifedipine; Ryanodine; Verapamil | 1992 |
Pertussis toxin stimulation of catecholamine release from adrenal medullary chromaffin cells: mechanism may be by direct activation of L-type and G-type calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Barium; Cadmium; Calcium Channel Blockers; Calcium Channels; Catecholamines; Cattle; Cells, Cultured; Chromaffin System; Dihydropyridines; Electric Conductivity; Membrane Potentials; Nifedipine; Pertussis Toxin; Verapamil; Virulence Factors, Bordetella | 1991 |
An investigation of the sensitivity of the ouabain-insensitive sodium efflux in single barnacle muscle fibers to pentachlorophenol.
Topics: Animals; Cadmium; Calcium; Calcium Channel Blockers; Cobalt; Cytosol; Dihydropyridines; Egtazic Acid; Gallic Acid; Hydrogen-Ion Concentration; Kinetics; Muscles; Osmolar Concentration; Ouabain; Pentachlorophenol; Ryanodine; Sodium; Stimulation, Chemical; Thoracica; Verapamil | 1991 |
Heparin binds with high affinity to voltage-dependent L-type Ca2+ channels. Evidence for an agonistic action.
Topics: Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Binding, Competitive; Calcium Channels; Carps; Cell Membrane; Cerebral Cortex; Dihydropyridines; Diltiazem; Electric Conductivity; Guinea Pigs; Heparin; Isradipine; Molecular Sequence Data; Muscles; Myocardium; Nicotinic Antagonists; Oxadiazoles; Polyelectrolytes; Polymers; Rabbits; Receptors, Nicotinic; Stereoisomerism; Verapamil | 1990 |
High and low affinity states of the dihydropyridine and phenylalkylamine receptors on the cardiac calcium channel and their interconversion by divalent cations.
Topics: Animals; Calcium; Cations, Divalent; Chickens; Dihydropyridines; Heart; Ion Channels; Isradipine; Magnesium; Myocardium; Nifedipine; Nitrendipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil | 1985 |
The effect of dihydropyridine calcium agonists and antagonists on neuronal voltage sensitive calcium channels.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Aminoquinolines; Animals; Brain Chemistry; Calcium; Calcium Channel Blockers; Cell Line; Dihydropyridines; Electric Stimulation; Glioma; In Vitro Techniques; Ion Channels; Neuroblastoma; Neurons; Nifedipine; Potassium; Pyridines; Rats; Synaptosomes; Verapamil | 1986 |
Purified calcium channels have three allosterically coupled drug receptors.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Allosteric Regulation; Amines; Animals; Calcium; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Guinea Pigs; Ion Channels; Isradipine; Muscles; Nifedipine; Oxadiazoles; Pyridines; Receptors, Drug; Verapamil | 1986 |
Dihydropyridine calcium antagonists and agonists in the isolated perfused Dahl rat kidney.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Glomerular Filtration Rate; Hypertension, Renal; In Vitro Techniques; Ion Channels; Kidney; Male; Nitrendipine; Perfusion; Pyridines; Rats; Rats, Inbred Strains; Renal Circulation; Sodium Chloride; Verapamil | 1987 |
Multiple calcium channels in synaptosomes: voltage dependence of 1,4-dihydropyridine binding and effects on function.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Calcium; Dihydropyridines; Ion Channels; Isradipine; Kinetics; Male; Nitrendipine; Oxadiazoles; Rats; Rats, Inbred Strains; Spectrometry, Fluorescence; Synaptosomes; Verapamil | 1988 |
Role of G-proteins in mediating dihydropyridine receptor coupling with voltage sensitive calcium channels.
Topics: Animals; Calcium Channels; Cell Line; Dihydropyridines; GTP-Binding Proteins; Marine Toxins; Nicardipine; Oxocins; Rats; Receptors, Nicotinic; Verapamil; Virulence Factors, Bordetella | 1988 |
A novel high affinity class of Ca2+ channel blockers.
Topics: Animals; Bepridil; Binding Sites; Calcium Channel Blockers; Cell Line; Dihydropyridines; Fluspirilene; Isradipine; Kinetics; Muscles; Oxadiazoles; Piperidines; Pyrrolidines; Rabbits; Rats; Structure-Activity Relationship; Thiazines; Verapamil | 1988 |
(-)-[3H] desmethoxyverapamil labels multiple calcium channel modulator receptors in brain and skeletal muscle membranes: differentiation by temperature and dihydropyridines.
Topics: Animals; Brain Chemistry; Calcium; Calcium Channels; Cell Membrane; Dihydropyridines; Female; Isradipine; Kinetics; Male; Muscles; Oxadiazoles; Pyridines; Rabbits; Receptors, Nicotinic; Stereoisomerism; Temperature; Tritium; Verapamil | 1986 |
The calcium channel antagonist omega-conotoxin inhibits secretion from peptidergic nerve terminals.
Topics: Animals; Arginine Vasopressin; Calcium Channel Blockers; Cell Membrane; Dihydropyridines; Electric Stimulation; In Vitro Techniques; Kinetics; Male; Mollusk Venoms; Nerve Endings; Nicardipine; omega-Conotoxin GVIA; Pituitary Gland, Posterior; Potassium; Rats; Reference Values; Verapamil | 1988 |
A novel 1,4-dihydropyridine-binding site on mitochondrial membranes from guinea-pig heart, liver and kidney.
Topics: Animals; Binding Sites; Centrifugation, Density Gradient; Dihydropyridines; Diltiazem; Guinea Pigs; Intracellular Membranes; Kidney; Mitochondria; Mitochondria, Heart; Mitochondria, Liver; Nitrendipine; Osmolar Concentration; Subcellular Fractions; Verapamil | 1988 |
Effects of calcium antagonists on phencyclidine behaviors.
Topics: Animals; Calcium Channel Blockers; Dihydropyridines; Drug Interactions; Male; Mice; Motor Activity; Motor Skills; Nifedipine; Phencyclidine; Prazosin; Pyridines; Verapamil | 1986 |
The interaction of phenylalkylamine calcium channel blockers with the 1,4-dihydropyridine binding site.
Topics: Animals; Binding Sites; Calcium Channel Blockers; Dihydropyridines; Heart; Kinetics; Male; Nifedipine; Nitrendipine; Pyridines; Rats; Rats, Inbred Strains; Receptors, Drug; Structure-Activity Relationship; Verapamil | 1986 |
Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists.
Topics: Animals; Binding Sites; Cattle; Dihydropyridines; Electrophysiology; Heart Conduction System; Ion Channels; Membrane Potentials; Nicardipine; Nifedipine; Nisoldipine; Nitrendipine; Purkinje Fibers; Pyridines; Verapamil | 1984 |
(-)-3H-desmethoxyverapamil labelling of putative calcium channels in brain: autoradiographic distribution and allosteric coupling to 1,4-dihydropyridine and diltiazem binding sites.
Topics: Animals; Autoradiography; Benzazepines; Binding Sites; Brain; Dihydropyridines; Diltiazem; Guinea Pigs; Hippocampus; In Vitro Techniques; Ion Channels; Kinetics; Membranes; Pyridines; Stereoisomerism; Verapamil | 1984 |
N-alkylated 1,4-dihydropyridines: new agents to overcome multidrug resistance.
Topics: Alkylation; Animals; Chemical Phenomena; Chemistry, Physical; Dihydropyridines; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Leukemia P388; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured; Verapamil; Vincristine | 1995 |
Differential effects of non-peptidic tachykinin receptor antagonists on Ca2+ channels.
Topics: Animals; Calcium Channels; Dihydropyridines; In Vitro Techniques; Isradipine; Muscles; Rats; Receptors, Tachykinin; Verapamil | 1994 |
Pharmacological analysis of voltage-dependent potassium currents in cultured skeletal myocytes of the frog Rana temporaria.
Topics: 4-Aminopyridine; Animals; Calcium Channel Blockers; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Electric Conductivity; Embryo, Nonmammalian; Membrane Potentials; Muscle, Skeletal; Nifedipine; Patch-Clamp Techniques; Potassium Channels; Quinidine; Rana temporaria; Time Factors; Verapamil | 1995 |
Involvement of both calcium influx and calcium mobilization in growth hormone-induced [Ca2+]i increases in Chinese hamster ovary cells.
Topics: Animals; Calcium; Calcium Channels; CHO Cells; Cricetinae; Dihydropyridines; Growth Hormone; Intracellular Fluid; Patch-Clamp Techniques; Rabbits; Thapsigargin; Verapamil | 1997 |
Multidrug resistance transporter P-glycoprotein has distinct but interacting binding sites for cytotoxic drugs and reversing agents.
Topics: Adenosine Triphosphatases; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Calcium Channel Blockers; CHO Cells; Cricetinae; Cytotoxins; Dihydropyridines; Drug Resistance, Multiple; Fibroblasts; Nicardipine; Nimodipine; Nitrendipine; Protein Binding; Verapamil; Vinblastine | 1998 |
Ca2+ channel modulation alters halothane-induced depression of ventricular myocytes.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Anesthetics, Inhalation; Animals; Calcium Channel Agonists; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Dihydropyridines; Dose-Response Relationship, Drug; Drug Synergism; Halothane; Heart Ventricles; Isradipine; Myocardial Contraction; Myocardium; Nifedipine; Rats; Rats, Wistar; Sarcolemma; Verapamil | 1998 |
Passive transfer of Lambert-Eaton myasthenic syndrome induces dihydropyridine sensitivity of ICa in mouse motor nerve terminals.
Topics: Animals; Autoantibodies; Binding, Competitive; Calcium; Calcium Channel Blockers; Dihydropyridines; Immunization, Passive; Lambert-Eaton Myasthenic Syndrome; Male; Mice; Mice, Inbred ICR; Motor Neurons; Nifedipine; omega-Agatoxin IVA; omega-Conotoxins; Peptides; Plasma; Potassium Channel Blockers; Presynaptic Terminals; Rats; Rats, Sprague-Dawley; Spider Venoms; Synaptosomes; Tetraethylammonium; Verapamil | 1998 |
Effects of long-acting versus short-acting calcium channel blockers among older survivors of acute myocardial infarction.
Topics: Aged; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Female; Humans; Male; Myocardial Infarction; Nicardipine; Nifedipine; Proportional Hazards Models; Retrospective Studies; Risk; Survival Analysis; Survivors; Verapamil | 1999 |
Nifedipine-activated Ca(2+) permeability in newborn rat cortical collecting duct cells in primary culture.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Animals, Newborn; Biological Transport; Calcium; Calcium Channel Blockers; Cell Membrane Permeability; Cells, Cultured; Cytosol; Dihydropyridines; Diltiazem; Egtazic Acid; Gadolinium; Hydrogen Peroxide; Isradipine; Kidney Cortex; Kidney Tubules, Collecting; Kinetics; Lanthanum; Nifedipine; Protamines; Rats; Rats, Sprague-Dawley; Thapsigargin; Verapamil | 2001 |
Marrubenol interacts with the phenylalkylamine binding site of the L-type calcium channel.
Topics: Animals; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Diterpenes; Furans; Ileum; In Vitro Techniques; Isradipine; Male; Membranes; Muscle Contraction; Muscle, Smooth; Potassium Chloride; Radioligand Assay; Rats; Rats, Wistar; Vasodilator Agents; Verapamil | 2004 |
Opposite effects of a single IIIS5 mutation on phenylalkylamine and dihydropyridine interaction with L-type Ca2+ channels.
Topics: Animals; Brain; Calcium; Calcium Channels; Calcium Channels, L-Type; Carrier Proteins; Cell Membrane; Dihydropyridines; DNA, Complementary; Dose-Response Relationship, Drug; Electrophysiology; Gallopamil; Homozygote; In Situ Hybridization; Isradipine; Kinetics; Mice; Mice, Transgenic; Microsomes; Models, Biological; Mutation; Oocytes; Protein Binding; Protein Structure, Tertiary; Recombinant Proteins; RNA, Complementary; Steroid Isomerases; Tyrosine; Verapamil; Xenopus laevis | 2004 |
Case studies in hypertension. Dihydropyridine/nondihydropyridine calcium channel blocker combination therapy.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Female; Humans; Hypertension; Lisinopril; Male; Middle Aged; Nifedipine; Verapamil | 2005 |
Evaluation of anticancer effects of newly synthesized dihydropyridine derivatives in comparison to verapamil and doxorubicin on T47D parental and resistant cell lines in vitro.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Dihydropyridines; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Inhibitory Concentration 50; Time Factors; Verapamil | 2008 |
Inclusion of patients who overdose with dihydropyridine calcium channel blockers would potentially increase clinical utility of hyperglycemia.
Topics: Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Overdose; Heart Rate; Humans; Hyperglycemia; Patient Selection; Verapamil | 2008 |
[Perspectives of inhibition of multidrug resistance during cancer chemotherapy, in vitro and in vivo experiments].
Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cytomegalovirus; Dihydropyridines; Disease Progression; Diterpenes; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; HSP90 Heat-Shock Proteins; Humans; Mice; Mice, Inbred DBA; Phenothiazines; Phenotype; Propylamines; Tylosin; Verapamil | 2009 |
Calcium channel antagonist exposures reported to the Poisons Information Center Erfurt.
Topics: Adolescent; Adult; Age Distribution; Aged; Calcium Channel Blockers; Child; Dihydropyridines; Diltiazem; Drug Overdose; Drug Synergism; Germany; Humans; Infant; Middle Aged; Poison Control Centers; Retrospective Studies; Verapamil; Young Adult | 2011 |