velnacrine and physostigmine

velnacrine has been researched along with physostigmine in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's8 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Curran, SM; Dougal, NJ; Ebmeier, KP; Goodwin, GM; Hanson, MT; Hunter, R; Murray, CL; Patterson, J; Siegfried, K; Wyper, DJ1
Badia, A; BaƱos, JE; Bosch, F; Morales, M2
Irie, T; Katsube, J; Natori, K; Okazaki, Y2
Cutler, NR; Sramek, JJ2
Duoyon, E; Lee, WS; Morrishow, AM; Prell, GD1

Trials

2 trial(s) available for velnacrine and physostigmine

ArticleYear
Effects of a single dose of the acetylcholinesterase inhibitor velnacrine on recognition memory and regional cerebral blood flow in Alzheimer's disease.
    Psychopharmacology, 1992, Volume: 108, Issue:1-2

    Topics: Aged; Alzheimer Disease; Cerebrovascular Circulation; Cholinesterase Inhibitors; Cognition; Double-Blind Method; Female; Humans; Male; Memory; Middle Aged; Physostigmine; Tacrine; Tomography, Emission-Computed, Single-Photon

1992
The target population in phase I clinical trials of cholinergic compounds in Alzheimer disease: the role of the "bridging study".
    Alzheimer disease and associated disorders, 1995,Fall, Volume: 9, Issue:3

    Topics: Alzheimer Disease; Cholinergic Agents; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Drug Tolerance; Humans; Physostigmine; Safety; Tacrine

1995

Other Studies

6 other study(ies) available for velnacrine and physostigmine

ArticleYear
Effects of velnacrine, tacrine and physostigmine on tetanic twitch responses at the rat neuromuscular junction.
    European journal of pharmacology, 1992, Nov-03, Volume: 222, Issue:1

    Topics: Animals; Cholinesterase Inhibitors; Diaphragm; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Neuromuscular Junction; Phrenic Nerve; Physostigmine; Rats; Rats, Sprague-Dawley; Tacrine

1992
Pharmacological and biochemical assessment of SM-10888, a novel cholinesterase inhibitor.
    Japanese journal of pharmacology, 1990, Volume: 53, Issue:2

    Topics: Aminacrine; Aminoacridines; Aminoquinolines; Animals; Body Temperature; Cerebral Cortex; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Nucleic Acids; Physostigmine; Rats; Salivation; Tacrine

1990
Effect of a novel CNS-selective cholinesterase inhibitor, SM-10888, on habituation and passive avoidance responses in mice.
    Japanese journal of pharmacology, 1990, Volume: 53, Issue:2

    Topics: Aminacrine; Aminoacridines; Aminoquinolines; Animals; Avoidance Learning; Cholinesterase Inhibitors; Cycloheximide; Electroshock; Exploratory Behavior; Habituation, Psychophysiologic; Male; Mice; Physostigmine; Tacrine

1990
Comparative effects of velnacrine, tacrine and physostigmine on the twitch responses in the rat phrenic-hemidiaphragm preparation.
    General pharmacology, 1993, Volume: 24, Issue:5

    Topics: Animals; Cholinesterase Inhibitors; Electric Stimulation; In Vitro Techniques; Male; Muscle Contraction; Neuromuscular Blocking Agents; Neuromuscular Junction; Phrenic Nerve; Physostigmine; Rats; Rats, Sprague-Dawley; Respiratory Muscles; Tacrine

1993
Scientific and ethical concerns in clinical trials in Alzheimer's patients: the bridging study.
    European journal of clinical pharmacology, 1995, Volume: 48, Issue:6

    Topics: Alzheimer Disease; Cholinesterase Inhibitors; Clinical Trials as Topic; Dihydropyridines; Ethics, Medical; Humans; Nootropic Agents; Oximes; Physostigmine; Psychotropic Drugs; Pyridines; Tacrine; Thiadiazoles

1995
Inhibitors of histamine methylation in brain promote formation of imidazoleacetic acid, which interacts with GABA receptors.
    Journal of neurochemistry, 1997, Volume: 68, Issue:1

    Topics: Animals; Brain; Gas Chromatography-Mass Spectrometry; Histamine; Imidazoles; Male; Methylation; Physostigmine; Pyrimethamine; Rats; Rats, Sprague-Dawley; Receptors, GABA; Tacrine

1997