Page last updated: 2024-09-04

vatalanib and staurosporine

vatalanib has been researched along with staurosporine in 10 studies

Compound Research Comparison

Studies
(vatalanib)
Trials
(vatalanib)
Recent Studies (post-2010)
(vatalanib)
Studies
(staurosporine)
Trials
(staurosporine)
Recent Studies (post-2010) (staurosporine)
27642984160286
27642986,27258976

Protein Interaction Comparison

ProteinTaxonomyvatalanib (IC50)staurosporine (IC50)
Chain A, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.015
Chain B, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.015
Chain A, Glycogen Synthase Kinase-3 BetaHomo sapiens (human)0.015
Chain A, Tyrosine-protein kinase ZAP-70Homo sapiens (human)0.0558
Chain A, Tyrosine-protein kinase SYKHomo sapiens (human)0.012
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)0.01
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1Homo sapiens (human)0.01
Chain X, Proto-oncogene tyrosine-protein kinase FynHomo sapiens (human)0.0048
Chain A, Serine/threonine-protein kinase TAO2Rattus norvegicus (Norway rat)3
epidermal growth factor receptor isoform a precursorHomo sapiens (human)0.4467
Serine/threonine-protein kinase Sgk1Homo sapiens (human)0.01
Cell division cycle 7-related protein kinaseHomo sapiens (human)0.0549
Serine/threonine-protein kinase PLK4Homo sapiens (human)0.0083
Serine/threonine-protein kinase 25Homo sapiens (human)0.0029
Citron Rho-interacting kinaseHomo sapiens (human)0.749
Dual specificity mitogen-activated protein kinase kinase 7Homo sapiens (human)0.9255
Telomerase reverse transcriptaseHomo sapiens (human)6.9517
Serine/threonine-protein kinase Chk1Homo sapiens (human)0.1772
Inhibitor of nuclear factor kappa-B kinase subunit betaHomo sapiens (human)0.5561
Aurora kinase AHomo sapiens (human)0.0087
Cyclin-G-associated kinaseHomo sapiens (human)0.011
Serine/threonine-protein kinase DCLK1Homo sapiens (human)0.267
Inhibitor of nuclear factor kappa-B kinase subunit alphaHomo sapiens (human)0.1265
Muscle, skeletal receptor tyrosine-protein kinaseHomo sapiens (human)0.1161
Mitogen-activated protein kinase 13Homo sapiens (human)0.4137
3-phosphoinositide-dependent protein kinase 1Homo sapiens (human)0.0072
Death-associated protein kinase 3Homo sapiens (human)0.0026
Mitogen-activated protein kinase kinase kinase 7Homo sapiens (human)0.0565
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.356
Dual specificity tyrosine-phosphorylation-regulated kinase 3Homo sapiens (human)0.0231
NUAK family SNF1-like kinase 1Homo sapiens (human)0.003
Cyclin-T1Homo sapiens (human)0.0118
Cyclin-T2Homo sapiens (human)0.0038
Tyrosine-protein kinase JAK2Homo sapiens (human)0.0016
Rho-associated protein kinase 2Homo sapiens (human)0.0045
Serine/threonine-protein kinase ULK1Homo sapiens (human)0.0096
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)0.1246
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)0.0011
Ribosomal protein S6 kinase alpha-4Homo sapiens (human)0.0071
Serine/threonine-protein kinase 16Homo sapiens (human)0.2385
Cyclin-KHomo sapiens (human)0.0948
Serine/threonine-protein kinase PAK 3Homo sapiens (human)0.0003
Serine/threonine-protein kinase 17BHomo sapiens (human)0.0258
Serine/threonine-protein kinase 10Homo sapiens (human)0.008
Serine/threonine-protein kinase D3Homo sapiens (human)0.1446
Cyclin-dependent kinase 14Homo sapiens (human)0.1145
G2/mitotic-specific cyclin-B2Homo sapiens (human)0.0107
Mitogen-activated protein kinase kinase kinase 6Homo sapiens (human)0.2829
Mitogen-activated protein kinase kinase kinase kinase 4Homo sapiens (human)0.0005
Serine/threonine-protein kinase LATS1Homo sapiens (human)0.013
Serine/threonine-protein kinase PAK 4Homo sapiens (human)0.0132
Serine/threonine-protein kinase Chk2Homo sapiens (human)0.0212
G1/S-specific cyclin-E2Homo sapiens (human)0.011
cAMP-dependent protein kinase catalytic subunit alphaBos taurus (cattle)0.0812
Tyrosine-protein kinase ABL1Homo sapiens (human)0.1233
Proto-oncogene tyrosine-protein kinase SrcGallus gallus (chicken)0.0063
Epidermal growth factor receptorHomo sapiens (human)0.083
RAF proto-oncogene serine/threonine-protein kinaseHomo sapiens (human)0.1281
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.0713
High affinity nerve growth factor receptorHomo sapiens (human)0.2403
Protein kinase C gamma typeHomo sapiens (human)0.1167
Platelet-derived growth factor receptor betaMus musculus (house mouse)0.002
Protein kinase C alpha typeRattus norvegicus (Norway rat)0.2327
Protein kinase C beta typeHomo sapiens (human)0.0684
Prostaglandin G/H synthase 1Ovis aries (sheep)0.056
Insulin receptorHomo sapiens (human)0.0706
Tyrosine-protein kinase LckHomo sapiens (human)0.1784
Tyrosine-protein kinase FynHomo sapiens (human)0.0929
Retinoblastoma-associated protein Homo sapiens (human)0.066
Cyclin-dependent kinase 1Homo sapiens (human)0.0075
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)0.0039
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.1269
Tyrosine-protein kinase YesHomo sapiens (human)0.0029
Tyrosine-protein kinase LynHomo sapiens (human)0.0012
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.0021
Insulin-like growth factor 1 receptorHomo sapiens (human)0.5534
Hepatocyte growth factor receptorHomo sapiens (human)0.1917
Tyrosine-protein kinase HCKHomo sapiens (human)0.0025
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)0.0004
Protein kinase C delta typeRattus norvegicus (Norway rat)0.274
Protein kinase C epsilon typeRattus norvegicus (Norway rat)0.274
Protein kinase C zeta typeRattus norvegicus (Norway rat)0.274
Platelet-derived growth factor receptor betaHomo sapiens (human)0.3707
Tyrosine-protein kinase FgrHomo sapiens (human)0.0009
Cytochrome P450 2D6Homo sapiens (human)0.0002
Mast/stem cell growth factor receptor KitHomo sapiens (human)0.0412
Breakpoint cluster region proteinHomo sapiens (human)0.0945
Calcium/calmodulin-dependent protein kinase type II subunit alphaRattus norvegicus (Norway rat)0.059
Serine/threonine-protein kinase pim-1Homo sapiens (human)0.0216
Fibroblast growth factor receptor 1Homo sapiens (human)0.0699
Cyclin-dependent kinase 1 Mus musculus (house mouse)0.008
Cyclin-dependent kinase 4Homo sapiens (human)0.0429
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)0.3642
Acyl-CoA desaturase 1Mus musculus (house mouse)3.4
Insulin receptor-related proteinHomo sapiens (human)0.0113
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.0088
Dipeptidyl peptidase 4Rattus norvegicus (Norway rat)0.003
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)4
Serine/threonine-protein kinase B-rafHomo sapiens (human)0.0107
Insulin receptorMus musculus (house mouse)0.2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoformHomo sapiens (human)0.0004
Platelet-derived growth factor receptor alphaHomo sapiens (human)0.0007
Tyrosine-protein kinase FerHomo sapiens (human)0.0008
Protein kinase C alpha typeHomo sapiens (human)0.0655
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)0.0115
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.0149
Cytochrome P450 11B2, mitochondrialHomo sapiens (human)0.011
Interferon-induced, double-stranded RNA-activated protein kinaseHomo sapiens (human)0.1
Amine oxidase [flavin-containing] BRattus norvegicus (Norway rat)0.0025
Casein kinase II subunit alpha'Homo sapiens (human)2.0215
Cyclin-A2Homo sapiens (human)0.009
Cannabinoid receptor 1Rattus norvegicus (Norway rat)0.01
Serine/threonine-protein kinase MAKHomo sapiens (human)0.0257
Ephrin type-A receptor 1Homo sapiens (human)0.0947
Fibroblast growth factor receptor 2Homo sapiens (human)0.0504
Receptor tyrosine-protein kinase erbB-3Homo sapiens (human)0.0106
Fibroblast growth factor receptor 4Homo sapiens (human)0.17
Fibroblast growth factor receptor 3Homo sapiens (human)0.0554
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)0.0137
Cyclin-OHomo sapiens (human)0.0015
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)0.0148
Ribosomal protein S6 kinase beta-1Homo sapiens (human)0.0007
Tyrosine-protein kinase JAK1Homo sapiens (human)0.004
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.028
G1/S-specific cyclin-D1Homo sapiens (human)0.0355
Protein kinase C eta typeHomo sapiens (human)0.1165
Cyclin-CHomo sapiens (human)0.0105
G1/S-specific cyclin-E1Homo sapiens (human)0.0108
Cyclin-dependent kinase 2Homo sapiens (human)0.0073
Beta-adrenergic receptor kinase 1Homo sapiens (human)1.1595
Platelet-derived growth factor receptor alpha Mus musculus (house mouse)0.002
Mitogen-activated protein kinase 3 Homo sapiens (human)4.6724
MAP/microtubule affinity-regulating kinase 3Homo sapiens (human)0.0004
cAMP-dependent protein kinase catalytic subunit alpha Rattus norvegicus (Norway rat)0.055
Mitogen-activated protein kinase 1Homo sapiens (human)2.6853
Ephrin type-A receptor 2Homo sapiens (human)0.1257
Ephrin type-A receptor 3Homo sapiens (human)0.0347
Ephrin type-A receptor 8Homo sapiens (human)0.1061
Ephrin type-B receptor 2Homo sapiens (human)0.1191
Leukocyte tyrosine kinase receptorHomo sapiens (human)0.0173
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)0.0137
G1/S-specific cyclin-D3Homo sapiens (human)0.055
Tyrosine-protein kinase receptor UFOHomo sapiens (human)0.0131
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)0.1848
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)0.4119
G protein-coupled receptor kinase 4Homo sapiens (human)0.0914
Kinesin-1 heavy chainHomo sapiens (human)0.0015
G protein-coupled receptor kinase 5Homo sapiens (human)0.0489
Hexokinase-4Homo sapiens (human)0.0006
Beta-adrenergic receptor kinase 2Homo sapiens (human)0.856
Vascular endothelial growth factor receptor 3Homo sapiens (human)0.0146
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.1791
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)0.026
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.0014
Bone morphogenetic protein receptor type-1AHomo sapiens (human)4.288
Activin receptor type-1BHomo sapiens (human)9.118
TGF-beta receptor type-1Homo sapiens (human)2.2823
Serine/threonine-protein kinase receptor R3Homo sapiens (human)0.85
Tyrosine-protein kinase CSKHomo sapiens (human)0.2071
Protein kinase C iota typeHomo sapiens (human)0.1739
Megakaryocyte-associated tyrosine-protein kinaseHomo sapiens (human)0.442
Tyrosine-protein kinase TecHomo sapiens (human)0.0338
Tyrosine-protein kinase TXKHomo sapiens (human)0.0203
Tyrosine-protein kinase ABL2Homo sapiens (human)0.0505
Tyrosine-protein kinase FRKHomo sapiens (human)0.0108
G protein-coupled receptor kinase 6Homo sapiens (human)0.0473
Tyrosine-protein kinase ZAP-70Homo sapiens (human)0.0175
Tyrosine-protein kinase SYKHomo sapiens (human)0.0057
Mitogen-activated protein kinase 8Homo sapiens (human)1.1067
Mitogen-activated protein kinase 9Homo sapiens (human)2.0555
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)0.863
Phosphorylase b kinase regulatory subunit alpha, liver isoformHomo sapiens (human)0.0005
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoformHomo sapiens (human)0.0005
Dual specificity mitogen-activated protein kinase kinase 3Homo sapiens (human)0.0099
Casein kinase I isoform alphaHomo sapiens (human)3.412
Casein kinase I isoform deltaHomo sapiens (human)1.4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)9
MAP kinase-activated protein kinase 2Homo sapiens (human)0.735
Cyclin-dependent kinase 8Homo sapiens (human)0.0105
Casein kinase I isoform epsilonHomo sapiens (human)1.4
Dual specificity protein kinase CLK1Homo sapiens (human)0.0108
Dual specificity protein kinase CLK2Homo sapiens (human)0.6508
Dual specificity protein kinase CLK3Homo sapiens (human)0.92
Glycogen synthase kinase-3 alphaHomo sapiens (human)0.0103
Glycogen synthase kinase-3 betaHomo sapiens (human)0.0435
D(1A) dopamine receptorSus scrofa (pig)0.001
Cyclin-dependent kinase 7Homo sapiens (human)0.2793
Cyclin-dependent kinase 9Homo sapiens (human)0.0474
Tyrosine-protein kinase BlkHomo sapiens (human)0.0011
Interleukin-1 receptor-associated kinase 1Homo sapiens (human)0.0377
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)0.0002
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)0.0046
cAMP-dependent protein kinase catalytic subunit PRKXHomo sapiens (human)0.0014
Cyclin-HHomo sapiens (human)0.2793
CDK-activating kinase assembly factor MAT1Homo sapiens (human)0.1216
Serine/threonine-protein kinase Nek2Homo sapiens (human)1.7683
Serine/threonine-protein kinase Nek4Homo sapiens (human)0.0851
Tyrosine-protein kinase JAK3Homo sapiens (human)0.0084
Dual specificity mitogen-activated protein kinase kinase 6Homo sapiens (human)0.0036
Serine/threonine-protein kinase PLK1Homo sapiens (human)0.4397
Death-associated protein kinase 1Homo sapiens (human)0.0101
LIM domain kinase 1Homo sapiens (human)0.0026
LIM domain kinase 2Homo sapiens (human)0.0956
Mitogen-activated protein kinase 12Homo sapiens (human)0.4512
Mitogen-activated protein kinase 10Homo sapiens (human)0.0731
5'-AMP-activated protein kinase subunit gamma-1Homo sapiens (human)1.1354
Ephrin type-B receptor 3Homo sapiens (human)1.2855
Ephrin type-A receptor 5Homo sapiens (human)0.0159
Ephrin type-B receptor 4Homo sapiens (human)0.1869
Ephrin type-B receptor 1Homo sapiens (human)0.0694
Ephrin type-A receptor 4Homo sapiens (human)0.0105
Serine/threonine-protein kinase SIK1Homo sapiens (human)0.0009
Calcium-dependent protein kinase 1Plasmodium falciparum K10.24
Protein kinase C gamma typeRattus norvegicus (Norway rat)0.2168
Casein kinase II subunit betaHomo sapiens (human)3.4
Casein kinase II subunit alphaHomo sapiens (human)3.4723
Protein kinase C beta typeRattus norvegicus (Norway rat)0.2029
SRSF protein kinase 2Homo sapiens (human)0.206
Casein kinase I isoform gamma-2Homo sapiens (human)1.9467
Cyclin-A1Homo sapiens (human)0.0013
Mitogen-activated protein kinase kinase kinase 9Homo sapiens (human)0.0044
MO15-related protein kinase Pfmrk Plasmodium falciparum (malaria parasite P. falciparum)4
Cyclin-dependent kinase 3Homo sapiens (human)0.0118
Cyclin-dependent kinase 6Homo sapiens (human)0.0395
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.0141
Cyclin-dependent kinase 16Homo sapiens (human)0.0206
Cyclin-dependent kinase 17Homo sapiens (human)0.0135
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.048
Protein kinase C epsilon typeHomo sapiens (human)0.0767
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)0.2314
Angiopoietin-1 receptorHomo sapiens (human)0.0823
Mitogen-activated protein kinase kinase kinase 10Homo sapiens (human)0.1952
Protein kinase C theta typeHomo sapiens (human)0.1168
Activin receptor type-1Homo sapiens (human)1.1354
Macrophage-stimulating protein receptorHomo sapiens (human)0.2195
Focal adhesion kinase 1Homo sapiens (human)0.078
Protein kinase C zeta typeHomo sapiens (human)0.1722
Protein kinase C delta typeHomo sapiens (human)0.1283
Tyrosine-protein kinase BTKHomo sapiens (human)0.0288
Aldehyde oxidaseHomo sapiens (human)0.0023
Tyrosine-protein kinase receptor TYRO3Homo sapiens (human)0.0177
Cyclin-dependent kinase 18Homo sapiens (human)0.0587
Activated CDC42 kinase 1Homo sapiens (human)0.0299
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)0.9655
Tyrosine-protein kinase ITK/TSKHomo sapiens (human)0.0068
Myotonin-protein kinaseHomo sapiens (human)0.1735
Mitogen-activated protein kinase kinase kinase 12Homo sapiens (human)0.0992
Tyrosine-protein kinase MerHomo sapiens (human)0.0331
Serine/threonine-protein kinase 4Homo sapiens (human)0.0013
Serine/threonine-protein kinase PAK 1Homo sapiens (human)0.0004
Dual specificity mitogen-activated protein kinase kinase 5Homo sapiens (human)0.0252
Mitogen-activated protein kinase 7Homo sapiens (human)4.0032
Serine/threonine-protein kinase PAK 2Homo sapiens (human)0.0021
Serine/threonine-protein kinase 3Homo sapiens (human)0.0034
Mitogen-activated protein kinase kinase kinase 1Homo sapiens (human)0.438
cGMP-dependent protein kinase 2Homo sapiens (human)0.0161
Rho-associated protein kinase 1Homo sapiens (human)0.0038
Non-receptor tyrosine-protein kinase TNK1Homo sapiens (human)0.0012
Calcium/calmodulin-dependent protein kinase type II subunit betaHomo sapiens (human)0.0018
Calcium/calmodulin-dependent protein kinase type II subunit gammaHomo sapiens (human)0.0026
Calcium/calmodulin-dependent protein kinase type II subunit deltaHomo sapiens (human)0.0024
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)0.0095
Bone morphogenetic protein receptor type-2Homo sapiens (human)1.94
Protein-tyrosine kinase 6Homo sapiens (human)0.484
cGMP-dependent protein kinase 1 Homo sapiens (human)0.0027
Cyclin-dependent kinase 13Homo sapiens (human)0.057
Calcium/calmodulin-dependent protein kinase type 1Homo sapiens (human)0.0032
Inhibitor of nuclear factor kappa-B kinase subunit epsilonHomo sapiens (human)0.0003
Protein-tyrosine kinase 2-betaHomo sapiens (human)0.0095
Maternal embryonic leucine zipper kinaseHomo sapiens (human)0.0006
Lysine--tRNA ligaseHomo sapiens (human)0.0049
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.0141
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrialHomo sapiens (human)0.0005
Serine/threonine-protein kinase D1Homo sapiens (human)0.1448
Serine/threonine-protein kinase 38Homo sapiens (human)0.0037
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)0.183
Ribosomal protein S6 kinase alpha-2Homo sapiens (human)0.0002
Ephrin type-A receptor 7Homo sapiens (human)0.0477
Ribosomal protein S6 kinase alpha-1Homo sapiens (human)0.0004
Dual specificity testis-specific protein kinase 1Homo sapiens (human)0.1995
Myosin light chain kinase, smooth muscleHomo sapiens (human)0.0448
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1Homo sapiens (human)0.037
Mitogen-activated protein kinase 11Homo sapiens (human)1
Serine/threonine-protein kinase STK11Homo sapiens (human)0.0598
Rhodopsin kinase GRK1Homo sapiens (human)0.068
Coiled-coil domain-containing protein 6Homo sapiens (human)0.0022
NT-3 growth factor receptorHomo sapiens (human)0.0002
Serine/threonine-protein kinase N1Homo sapiens (human)0.0025
Serine/threonine-protein kinase N2Homo sapiens (human)0.0055
Mitogen-activated protein kinase 14Homo sapiens (human)0.5052
Calcium/calmodulin-dependent protein kinase type IVHomo sapiens (human)0.1475
Mitogen-activated protein kinase kinase kinase 11Homo sapiens (human)0.016
BDNF/NT-3 growth factors receptorHomo sapiens (human)0.0004
MAP kinase-activated protein kinase 3Homo sapiens (human)2.775
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoformHomo sapiens (human)0.0017
Discoidin domain-containing receptor 2Homo sapiens (human)0.0008
Thioredoxin reductase 1, cytoplasmicHomo sapiens (human)0.0432
Rho-associated protein kinase 2Bos taurus (cattle)0.0417
Myosin light chain kinase 3Homo sapiens (human)0.1585
Serine/threonine-protein kinase SBK1Homo sapiens (human)0.1464
Mitogen-activated protein kinase kinase kinase 19Homo sapiens (human)0.0087
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)0.0077
Mitogen-activated protein kinase kinase kinase 21Homo sapiens (human)1.1175
Serine/threonine-protein kinase MRCK alphaHomo sapiens (human)0.0032
Sigma non-opioid intracellular receptor 1Cavia porcellus (domestic guinea pig)0.0067
Testis-specific serine/threonine-protein kinase 1Mus musculus (house mouse)0.0003
Dual specificity tyrosine-phosphorylation-regulated kinase 1ARattus norvegicus (Norway rat)0.012
Protein kinase C eta typeRattus norvegicus (Norway rat)0.274
Serine/threonine-protein kinase MRCK gammaHomo sapiens (human)0.0005
Calcium/calmodulin-dependent protein kinase type 1BHomo sapiens (human)0.0044
Serine/threonine-protein kinase Nek5Homo sapiens (human)0.0864
Serine/threonine-protein kinase N3Homo sapiens (human)0.0105
Serine/threonine-protein kinase ULK3Homo sapiens (human)0.0027
Kinase suppressor of Ras 2Homo sapiens (human)5.4
Dual serine/threonine and tyrosine protein kinaseHomo sapiens (human)0.0552
Serine/threonine-protein kinase/endoribonuclease IRE2Homo sapiens (human)0.0416
Serine/threonine-protein kinase MARK2Homo sapiens (human)0.0001
Serine/threonine-protein kinase TAO1Homo sapiens (human)0.0008
Serine/threonine-protein kinase Nek8Homo sapiens (human)0.0263
Serine/threonine-protein kinase tousled-like 2Homo sapiens (human)0.0035
Serine/threonine-protein kinase 32CHomo sapiens (human)0.232
Serine/threonine-protein kinase pim-3Homo sapiens (human)0.0001
Myosin light chain kinase family member 4Homo sapiens (human)0.0537
Homeodomain-interacting protein kinase 1Homo sapiens (human)2.639
Calcium/calmodulin-dependent protein kinase type 1DHomo sapiens (human)0.0003
Mitogen-activated protein kinase kinase kinase kinase 3Homo sapiens (human)0.0001
Kinase suppressor of Ras 1Homo sapiens (human)6.265
Cyclin-dependent kinase-like 3Homo sapiens (human)1.1
MAP kinase-activated protein kinase 5Homo sapiens (human)0.212
Serine/threonine-protein kinase BRSK2Homo sapiens (human)0.0028
Serine/threonine-protein kinase NIM1Homo sapiens (human)0.1102
Serine/threonine-protein kinase ULK2Homo sapiens (human)0.0032
Misshapen-like kinase 1Homo sapiens (human)0.0004
Serine/threonine-protein kinase DCLK2Homo sapiens (human)0.089
Calcium/calmodulin-dependent protein kinase kinase 1Homo sapiens (human)0.0359
Casein kinase I isoform alpha-likeHomo sapiens (human)1.84
Cyclin-YHomo sapiens (human)0.0518
Homeodomain-interacting protein kinase 4Homo sapiens (human)0.226
Myosin-IIIaHomo sapiens (human)0.0425
Serine/threonine-protein kinase Nek11Homo sapiens (human)0.521
Protein odd-skipped-related 1Homo sapiens (human)0.0402
Mitogen-activated protein kinase 15Homo sapiens (human)0.0081
Serine/threonine-protein kinase Nek9Homo sapiens (human)0.101
Serine/threonine-protein kinase BRSK1Homo sapiens (human)0.0007
Serine/threonine-protein kinase haspinHomo sapiens (human)0.0422
Rhodopsin kinase GRK7Homo sapiens (human)0.0053
G2/mitotic-specific cyclin-B3Homo sapiens (human)0.0107
Myosin-IIIbHomo sapiens (human)0.0058
Dual specificity tyrosine-phosphorylation-regulated kinase 2Homo sapiens (human)0.18
Phosphorylase b kinase regulatory subunit betaHomo sapiens (human)0.0005
Serine/threonine-protein kinase Sgk3Homo sapiens (human)0.073
Aurora kinase BHomo sapiens (human)0.007
Lymphokine-activated killer T-cell-originated protein kinaseHomo sapiens (human)0.0691
MAP/microtubule affinity-regulating kinase 4Homo sapiens (human)0.0001
Calcium/calmodulin-dependent protein kinase type 1GHomo sapiens (human)0.0047
Testis-specific serine/threonine-protein kinase 2Homo sapiens (human)0.0038
Testis-specific serine/threonine-protein kinase 3Homo sapiens (human)0.0051
Serine/threonine-protein kinase Nek1Homo sapiens (human)0.0122
PAS domain-containing serine/threonine-protein kinaseHomo sapiens (human)0.0107
Calcium/calmodulin-dependent protein kinase kinase 2Homo sapiens (human)0.0246
SRSF protein kinase 1Homo sapiens (human)0.0337
Mitogen-activated protein kinase kinase kinase 14Homo sapiens (human)2.3
Mitogen-activated protein kinase kinase kinase 5Homo sapiens (human)0.215
Mitogen-activated protein kinase kinase kinase 3Homo sapiens (human)0.0092
MAP kinase-interacting serine/threonine-protein kinase 1Homo sapiens (human)0.0531
Testis-specific serine/threonine-protein kinase 6Homo sapiens (human)0.1525
Serine/threonine-protein kinase 33Homo sapiens (human)0.0374
Serine/threonine-protein kinase D2Homo sapiens (human)0.0014
NUAK family SNF1-like kinase 2Homo sapiens (human)0.0018
Serine/threonine-protein kinase SIK2Homo sapiens (human)0.3669
Myosin light chain kinase 2, skeletal/cardiac muscleHomo sapiens (human)0.0147
STE20-like serine/threonine-protein kinase Homo sapiens (human)0.0142
Serine/threonine-protein kinase TAO3Homo sapiens (human)0.0017
Homeodomain-interacting protein kinase 2Homo sapiens (human)0.3655
Tyrosine-protein kinase SrmsHomo sapiens (human)6.5
Homeodomain-interacting protein kinase 3Homo sapiens (human)0.456
Serine/threonine-protein kinase PLK3Homo sapiens (human)0.203
Inactive tyrosine-protein kinase PEAK1Homo sapiens (human)0.0025
Dual specificity protein kinase CLK4Homo sapiens (human)0.0723
MAP kinase-interacting serine/threonine-protein kinase 2Homo sapiens (human)0.0221
Serine/threonine-protein kinase Sgk2Homo sapiens (human)0.0159
Casein kinase I isoform gamma-1Homo sapiens (human)5.3367
NADPH oxidase 4Homo sapiens (human)0.0708
Serine/threonine-protein kinase PAK 6Homo sapiens (human)0.0327
SNF-related serine/threonine-protein kinaseHomo sapiens (human)0.0059
Serine/threonine-protein kinase LATS2Homo sapiens (human)0.0062
Interleukin-1 receptor-associated kinase 4Homo sapiens (human)0.0122
Serine/threonine-protein kinase 32BHomo sapiens (human)0.0375
Cyclin-dependent kinase 12Homo sapiens (human)0.053
Serine/threonine-protein kinase PLK2Homo sapiens (human)0.546
Serine/threonine-protein kinase MARK1Homo sapiens (human)0.0003
Serine/threonine-protein kinase pim-2Homo sapiens (human)0.0813
Serine/threonine-protein kinase PAK 5Homo sapiens (human)0.0039
Serine/threonine-protein kinase 26Homo sapiens (human)0.0124
Serine/threonine-protein kinase NLKHomo sapiens (human)0.0666
Ribosomal protein S6 kinase beta-2Homo sapiens (human)0.0015
Protein DBF4 homolog AHomo sapiens (human)0.0549
Serine/threonine-protein kinase 17AHomo sapiens (human)0.0386
STE20/SPS1-related proline-alanine-rich protein kinaseHomo sapiens (human)0.0158
Ephrin type-A receptor 6Homo sapiens (human)0.0161
Serine/threonine-protein kinase TBK1Homo sapiens (human)0.003
Death-associated protein kinase 2Homo sapiens (human)0.0064
Ribosomal protein S6 kinase alpha-6Homo sapiens (human)0.0001
TRAF2 and NCK-interacting protein kinaseHomo sapiens (human)0.0103
Serine/threonine-protein kinase tousled-like 1Homo sapiens (human)0.0295
Serine/threonine-protein kinase TAO2Homo sapiens (human)0.0076
ALK tyrosine kinase receptorHomo sapiens (human)0.0044
SRSF protein kinase 3Homo sapiens (human)1.77
Serine/threonine-protein kinase ICKHomo sapiens (human)0.0443
Aurora kinase CHomo sapiens (human)0.0022
Calcium/calmodulin-dependent protein kinase type II subunit alphaHomo sapiens (human)0.0024
Protein kinase C theta typeRattus norvegicus (Norway rat)0.274
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)0.3701
Serine/threonine-protein kinase 38-likeHomo sapiens (human)0.0012
Serine/threonine-protein kinase SIK3Homo sapiens (human)0.1541
Mitogen-activated protein kinase kinase kinase 2Homo sapiens (human)0.0335
Serine/threonine-protein kinase WNK2Homo sapiens (human)1.455
Dual specificity tyrosine-phosphorylation-regulated kinase 1BHomo sapiens (human)0.0017
5'-AMP-activated protein kinase subunit beta-1Homo sapiens (human)1.1354
Mitogen-activated protein kinase kinase kinase kinase 5Homo sapiens (human)0.0002
Serine/threonine-protein kinase MRCK betaHomo sapiens (human)0.0027
Serine/threonine-protein kinase 24Homo sapiens (human)0.0065
Casein kinase I isoform gamma-3Homo sapiens (human)2.675
Chain A, Ribosomal protein S6 kinase alpha-1Homo sapiens (human)0.0003
Chain X, Tyrosine-protein kinase LynHomo sapiens (human)0.0013

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (60.00)29.6817
2010's4 (40.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atteridge, CE; Azimioara, MD; Benedetti, MG; Biggs, WH; Carter, TA; Ciceri, P; Edeen, PT; Fabian, MA; Floyd, M; Ford, JM; Galvin, M; Gerlach, JL; Grotzfeld, RM; Herrgard, S; Insko, DE; Insko, MA; Lai, AG; Lélias, JM; Lockhart, DJ; Mehta, SA; Milanov, ZV; Patel, HK; Treiber, DK; Velasco, AM; Wodicka, LM; Zarrinkar, PP1
Bullock, AN; Fedorov, O; Knapp, S; Marsden, B; Müller, S; Pogacic, V; Rellos, P; Schwaller, J; Sundström, M1
Atteridge, CE; Campbell, BT; Chan, KW; Ciceri, P; Davis, MI; Edeen, PT; Faraoni, R; Floyd, M; Gallant, P; Herrgard, S; Hunt, JP; Karaman, MW; Lockhart, DJ; Milanov, ZV; Morrison, MJ; Pallares, G; Patel, HK; Pritchard, S; Treiber, DK; Wodicka, LM; Zarrinkar, PP1
Russu, WA; Shallal, HM1
Ciceri, P; Davis, MI; Herrgard, S; Hocker, M; Hunt, JP; Pallares, G; Treiber, DK; Wodicka, LM; Zarrinkar, PP1
Al-Mazaideh, GM; Erdmann, F; Göllner, C; Rohe, A; Schmidt, M; Sippl, W; Wichapong, K1
Campochiaro, PA; Melia, M; Saishin, Y; Seo, MS; Takahashi, K1
Bodis, S; Hofstetter, B; Pruschy, M; Riesterer, O; Tenzer, A; Vuong, V; Zingg, D1
Bui, B; Italiano, A1
Backman, JT; Filppula, AM; Mustonen, TM1

Reviews

1 review(s) available for vatalanib and staurosporine

ArticleYear
[Gastrointestinal stromal tumors: molecular aspects and therapeutic implications].
    Bulletin du cancer, 2008, Volume: 95, Issue:1

    Topics: Antineoplastic Agents; Benzamides; Benzenesulfonates; Disease Progression; Drug Resistance, Neoplasm; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Mutation; Neoplasm Proteins; Niacinamide; Oligonucleotides; Phenylurea Compounds; Phthalazines; Piperazines; Piperidines; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyridines; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Sorafenib; Staurosporine; Sunitinib; Thiazoles

2008

Other Studies

9 other study(ies) available for vatalanib and staurosporine

ArticleYear
A small molecule-kinase interaction map for clinical kinase inhibitors.
    Nature biotechnology, 2005, Volume: 23, Issue:3

    Topics: Benzamides; Drug Design; Escherichia coli; Escherichia coli Proteins; Imatinib Mesylate; Microchemistry; Pharmaceutical Preparations; Piperazines; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Pyrimidines

2005
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Dec-18, Volume: 104, Issue:51

    Topics: Amino Acid Sequence; Binding Sites; Clinical Trials as Topic; Drug Evaluation, Preclinical; Enzyme Stability; Humans; Molecular Sequence Data; Phylogeny; Protein Array Analysis; Protein Conformation; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases

2007
A quantitative analysis of kinase inhibitor selectivity.
    Nature biotechnology, 2008, Volume: 26, Issue:1

    Topics: Binding Sites; Enzyme Activation; Humans; Phosphotransferases; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Proteome; Quantitative Structure-Activity Relationship

2008
Discovery, synthesis, and investigation of the antitumor activity of novel piperazinylpyrimidine derivatives.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Piperazines; Protein Kinase Inhibitors; Protein Kinases; Pyrimidines; Stereoisomerism; Structure-Activity Relationship

2011
Comprehensive analysis of kinase inhibitor selectivity.
    Nature biotechnology, 2011, Oct-30, Volume: 29, Issue:11

    Topics: Catalysis; Drug Design; Enzyme Stability; High-Throughput Screening Assays; Humans; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Proteomics; Signal Transduction; Substrate Specificity

2011
Evaluation of potential Myt1 kinase inhibitors by TR-FRET based binding assay.
    European journal of medicinal chemistry, 2013, Volume: 61

    Topics: Dose-Response Relationship, Drug; Fluorescence Resonance Energy Transfer; Glycolipids; Humans; Membrane Proteins; Models, Molecular; Molecular Structure; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Structure-Activity Relationship

2013
The kinase inhibitor PKC412 suppresses epiretinal membrane formation and retinal detachment in mice with proliferative retinopathies.
    Investigative ophthalmology & visual science, 2003, Volume: 44, Issue:8

    Topics: Angiogenesis Inhibitors; Animals; Cell Division; Enzyme Inhibitors; Epiretinal Membrane; Glial Fibrillary Acidic Protein; Immunoenzyme Techniques; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phthalazines; Platelet-Derived Growth Factor; Protein Kinase C; Proto-Oncogene Proteins c-sis; Pyridines; Retina; Retinal Detachment; Staurosporine

2003
Novel radiosensitizers for locally advanced epithelial tumors: inhibition of the PI3K/Akt survival pathway in tumor cells and in tumor-associated endothelial cells as a novel treatment strategy?
    International journal of radiation oncology, biology, physics, 2004, Feb-01, Volume: 58, Issue:2

    Topics: Cell Survival; Combined Modality Therapy; Down-Regulation; Endothelial Cells; Enzyme Inhibitors; ErbB Receptors; Neoplasm Proteins; Neoplasms, Glandular and Epithelial; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phthalazines; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyridines; Pyrimidines; Pyrroles; Radiation-Sensitizing Agents; Receptors, Vascular Endothelial Growth Factor; Staurosporine

2004
In Vitro Screening of Six Protein Kinase Inhibitors for Time-Dependent Inhibition of CYP2C8 and CYP3A4: Possible Implications with regard to Drug-Drug Interactions.
    Basic & clinical pharmacology & toxicology, 2018, Volume: 123, Issue:6

    Topics: Benzamides; Benzimidazoles; Cytochrome P-450 CYP2C8; Cytochrome P-450 CYP2C8 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Drug Interactions; Humans; Indoles; Inhibitory Concentration 50; Microsomes, Liver; Phthalazines; Piperidines; Pyridines; Pyridones; Pyrimidinones; Quinolones; Staurosporine; Thiazoles

2018