Page last updated: 2024-09-04

vatalanib and spiperone

vatalanib has been researched along with spiperone in 2 studies

Compound Research Comparison

Studies (vatalanib)	Trials (vatalanib)	Recent Studies (post-2010) (vatalanib)	Studies (spiperone)	Trials (spiperone)	Recent Studies (post-2010) (spiperone)
276	42	98	2,944	13	85

Protein Interaction Comparison

Protein	Taxonomy	spiperone (IC50)
Bile salt export pump	Homo sapiens (human)	10
D(2) dopamine receptor	Homo sapiens (human)	0.0008
Alpha-1B adrenergic receptor	Rattus norvegicus (Norway rat)	0.097
D(4) dopamine receptor	Homo sapiens (human)	0.0005
Alpha-1D adrenergic receptor	Rattus norvegicus (Norway rat)	0.097
Histamine H1 receptor	Cavia porcellus (domestic guinea pig)	0.097
D(3) dopamine receptor	Homo sapiens (human)	0.0635
Alpha-1A adrenergic receptor	Rattus norvegicus (Norway rat)	0.097
D(2) dopamine receptor	Rattus norvegicus (Norway rat)	0.0001
Sigma non-opioid intracellular receptor 1	Homo sapiens (human)	0.955

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Bouvier, M; Deng, H; Dsouza, NR; Johnson, ME; Lee, H; Ren, J	1

Other Studies

2 other study(ies) available for vatalanib and spiperone

Article	Year
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Discovery of small molecule inhibitors of adenovirus by disrupting E3-19K/HLA-A2 interactions. Bioorganic & medicinal chemistry letters, 2018, 09-15, Volume: 28, Issue:17 Topics: Adenoviridae; Adenovirus E3 Proteins; Antiviral Agents; Dose-Response Relationship, Drug; Drug Discovery; HLA-A2 Antigen; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Small Molecule Libraries; Structure-Activity Relationship	2018

Article

Year

Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.

Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012

Discovery of small molecule inhibitors of adenovirus by disrupting E3-19K/HLA-A2 interactions.

Bioorganic & medicinal chemistry letters, 2018, 09-15, Volume: 28, Issue:17

Topics: Adenoviridae; Adenovirus E3 Proteins; Antiviral Agents; Dose-Response Relationship, Drug; Drug Discovery; HLA-A2 Antigen; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Small Molecule Libraries; Structure-Activity Relationship

2018