Compounds > vatalanib
Page last updated: 2024-09-04

vatalanib and paclitaxel

vatalanib has been researched along with paclitaxel in 2 studies

Compound Research Comparison

Studies
(vatalanib)		Trials
(vatalanib)		Recent Studies (post-2010)
(vatalanib)		Studies
(paclitaxel)		Trials
(paclitaxel)		Recent Studies (post-2010) (paclitaxel)
276429831,8745,72915,395

Protein Interaction Comparison

ProteinTaxonomyvatalanib (IC50)paclitaxel (IC50)
Integrin beta-3Homo sapiens (human)0.034
Integrin alpha-V Homo sapiens (human)0.034
ATP-dependent translocase ABCB1Homo sapiens (human)2.598
Botulinum neurotoxin type A Clostridium botulinum5.2
UDP-glucuronosyltransferase 2B7Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1-6Homo sapiens (human)4.9
Substance-K receptorHomo sapiens (human)6.125
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1A4Homo sapiens (human)4.9
UDP-glucuronosyltransferase 2B10 Homo sapiens (human)4.9
Delta-type opioid receptorHomo sapiens (human)4.202
Tyrosine-protein kinase MerHomo sapiens (human)4.9
Tubulin beta-3 chainHomo sapiens (human)0.0082
Beta-tubulin Leishmania donovani1
Nucleotide-binding oligomerization domain-containing protein 2Homo sapiens (human)7.9433
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)0.26
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.28

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chiorean, EG; Hall, SD; Jones, DR; Malireddy, S; Schneider, B; Sloop, MI; Sweeney, CJ; Waddell, MJ; Younger, AE; Yu, M1
Åhgren, A; Hasumi, Y; Heldin, CH; Hellberg, C; Kłosowska-Wardęga, A1

Trials

1 trial(s) available for vatalanib and paclitaxel

ArticleYear
A phase I dose escalation and pharmacokinetic study of vatalanib (PTK787/ZK 222584) in combination with paclitaxel in patients with advanced solid tumors.
    Cancer chemotherapy and pharmacology, 2010, Volume: 66, Issue:3

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Paclitaxel; Phthalazines; Pyridines; Transaminases; Treatment Outcome

2010

Other Studies

1 other study(ies) available for vatalanib and paclitaxel

ArticleYear
Combination therapy using imatinib and vatalanib improves the therapeutic efficiency of paclitaxel towards a mouse melanoma tumor.
    Melanoma research, 2011, Volume: 21, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Becaplermin; Benzamides; Cell Line, Tumor; Cell Proliferation; Drug Synergism; Imatinib Mesylate; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Paclitaxel; Phthalazines; Piperazines; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Proto-Oncogene Proteins c-sis; Pyridines; Pyrimidines; RNA, Small Interfering; Signal Transduction

2011