Compounds > vatalanib
Page last updated: 2024-09-04

vatalanib and nvp-tae684

vatalanib has been researched along with nvp-tae684 in 3 studies

Compound Research Comparison

Studies
(vatalanib)		Trials
(vatalanib)		Recent Studies (post-2010)
(vatalanib)		Studies
(nvp-tae684)		Trials
(nvp-tae684)		Recent Studies (post-2010) (nvp-tae684)
276429874063

Protein Interaction Comparison

ProteinTaxonomyvatalanib (IC50)nvp-tae684 (IC50)
Tyrosine-protein kinase JAK2Homo sapiens (human)1.505
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)0.065
Tyrosine-protein kinase ABL1Homo sapiens (human)1.048
Insulin receptorHomo sapiens (human)2.5164
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)0.569
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.0501
Tyrosine-protein kinase LynHomo sapiens (human)1.308
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)1.385
Insulin-like growth factor 1 receptorHomo sapiens (human)0.0003
Hepatocyte growth factor receptorHomo sapiens (human)1.667
Proto-oncogene tyrosine-protein kinase ROSHomo sapiens (human)0.002
Platelet-derived growth factor receptor betaHomo sapiens (human)3.22
Fibroblast growth factor receptor 1Homo sapiens (human)0.6175
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)1.146
Insulin receptor Rattus norvegicus (Norway rat)1.2
Vascular endothelial growth factor receptor 1 Homo sapiens (human)0.872
Fibroblast growth factor receptor 4Homo sapiens (human)0.652
Fibroblast growth factor receptor 3Homo sapiens (human)0.085
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)2.309
Vascular endothelial growth factor receptor 2Homo sapiens (human)2.123
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.7385
Tyrosine-protein kinase ZAP-70Homo sapiens (human)1.598
Cytoplasmic tyrosine-protein kinase BMXHomo sapiens (human)1.578
Ephrin type-B receptor 4Homo sapiens (human)1.3
ALK tyrosine kinase receptorMus musculus (house mouse)0.01
Angiopoietin-1 receptorHomo sapiens (human)0.5895
Macrophage-stimulating protein receptorHomo sapiens (human)1.634
Lysine--tRNA ligaseHomo sapiens (human)0.88
BDNF/NT-3 growth factors receptorHomo sapiens (human)2.018
Leucine-rich repeat serine/threonine-protein kinase 2Homo sapiens (human)0.0323
Echinoderm microtubule-associated protein-like 4Homo sapiens (human)0.03
ALK tyrosine kinase receptorHomo sapiens (human)0.0138

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hajduk, PJ; Johnson, EF; Kifle, L; Merta, PJ; Metz, JT; Soni, NB1
Ciceri, P; Davis, MI; Herrgard, S; Hocker, M; Hunt, JP; Pallares, G; Treiber, DK; Wodicka, LM; Zarrinkar, PP1
Cahya, S; Cummins, DJ; Gao, C; Iversen, PW; Nicolaou, CA; Vieth, M; Wang, J; Watson, IA1

Other Studies

3 other study(ies) available for vatalanib and nvp-tae684

ArticleYear
Navigating the kinome.
    Nature chemical biology, 2011, Volume: 7, Issue:4

    Topics: Drug Design; Pharmacogenetics; Protein Kinases; Proteome; Systems Biology

2011
Comprehensive analysis of kinase inhibitor selectivity.
    Nature biotechnology, 2011, Oct-30, Volume: 29, Issue:11

    Topics: Catalysis; Drug Design; Enzyme Stability; High-Throughput Screening Assays; Humans; Protein Binding; Protein Kinase Inhibitors; Protein Kinases; Proteomics; Signal Transduction; Substrate Specificity

2011
Selectivity data: assessment, predictions, concordance, and implications.
    Journal of medicinal chemistry, 2013, Sep-12, Volume: 56, Issue:17

    Topics: Computer Simulation; Drug Discovery

2013