vasoactive-intestinal-peptide has been researched along with bemesetron* in 1 studies
1 other study(ies) available for vasoactive-intestinal-peptide and bemesetron
Article | Year |
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Vasoactive intestinal polypeptide facilitates the late component of the 5-hydroxytryptamine-induced discharge in the cat superior cervical ganglion.
The intra-arterial administration of vasoactive intestinal polypeptide (VIP, 1-10 micrograms, i.a.) to the cat superior cervical ganglion facilitated or unmasked the late component but not the early component of the 5-hydroxytryptamine (5-HT, 0.5-50 micrograms, i.a.)-induced postganglionic discharge. The facilitation occurred in acutely and chronically decentralized ganglia. The early and late 5-HT discharges were blocked by MDL-72222, a 5-HT antagonist, but not by cholinergic antagonists. These data together with previous observations indicate that VIP selectively facilitates slow cholinergic and non-cholinergic excitatory mechanisms in autonomic ganglia. Topics: Animals; Atropine; Autonomic Fibers, Postganglionic; Cats; Female; Ganglia, Sympathetic; Hexamethonium; Hexamethonium Compounds; Male; Membrane Potentials; Serotonin; Serotonin Antagonists; Tropanes; Vasoactive Intestinal Peptide | 1987 |