Page last updated: 2024-09-04

varespladib and varespladib methyl

varespladib has been researched along with varespladib methyl in 4 studies

Compound Research Comparison

Studies
(varespladib)
Trials
(varespladib)
Recent Studies (post-2010)
(varespladib)
Studies
(varespladib methyl)
Trials
(varespladib methyl)
Recent Studies (post-2010) (varespladib methyl)
80114922419

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (25.00)24.3611
2020's3 (75.00)2.80

Authors

AuthorsStudies
Bickler, P; Lewin, M; Merkel, J; Samuel, S1
Gutiérrez, JM; Lewin, MR; Lomonte, B; Williams, DJ1
Fortes-Dias, CL; Garrido Cavalcante, WL; Gonçalves de Abreu, TA; Maciel, FV; Ortolani, PL; Ramos Pinto, ÊK; Valério Souza, NM1
Akpunonu, PD; Bammigatti, C; Bhalla, A; Carter, RW; Gerardo, CJ; Kotehal, SD; Kumar, S; Lewin, MR; Manikath, N; Mukherjee, PP; Platts-Mills, TF; Samuel, SP; Shirazi, FM1

Trials

1 trial(s) available for varespladib and varespladib methyl

ArticleYear
The BRAVO Clinical Study Protocol: Oral Varespladib for Inhibition of Secretory Phospholipase A2 in the Treatment of Snakebite Envenoming.
    Toxins, 2022, 12-28, Volume: 15, Issue:1

    Topics: Clinical Trials, Phase II as Topic; Female; Humans; Male; Multicenter Studies as Topic; Phospholipases A2, Secretory; Randomized Controlled Trials as Topic; Snake Bites

2022

Other Studies

3 other study(ies) available for varespladib and varespladib methyl

ArticleYear
Varespladib (LY315920) Appears to Be a Potent, Broad-Spectrum, Inhibitor of Snake Venom Phospholipase A2 and a Possible Pre-Referral Treatment for Envenomation.
    Toxins, 2016, 08-25, Volume: 8, Issue:9

    Topics: Acetates; Animals; Antidotes; Disease Models, Animal; Dose-Response Relationship, Drug; Elapid Venoms; Indoles; Keto Acids; Mice; Phospholipase A2 Inhibitors; Phospholipases A2; Prodrugs; Rats, Sprague-Dawley; Reptilian Proteins; Snake Bites; Time Factors; Viper Venoms

2016
Varespladib (LY315920) and Methyl Varespladib (LY333013) Abrogate or Delay Lethality Induced by Presynaptically Acting Neurotoxic Snake Venoms.
    Toxins, 2020, 02-20, Volume: 12, Issue:2

    Topics: Acetates; Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Indoles; Keto Acids; Lethal Dose 50; Mice; Neurotoxicity Syndromes; Phospholipase A2 Inhibitors; Phospholipases A2; Snake Bites; Snake Venoms; Survival Analysis; Time Factors

2020
Varespladib (LY315920) prevents neuromuscular blockage and myotoxicity induced by crotoxin on mouse neuromuscular preparations.
    Toxicon : official journal of the International Society on Toxinology, 2021, Oct-30, Volume: 202

    Topics: Acetates; Animals; Crotalid Venoms; Crotoxin; Indoles; Keto Acids; Mice; Myotoxicity

2021