varenicline has been researched along with nelfinavir in 2 studies
| Studies (varenicline) | Trials (varenicline) | Recent Studies (post-2010) (varenicline) | Studies (nelfinavir) | Trials (nelfinavir) | Recent Studies (post-2010) (nelfinavir) |
|---|---|---|---|---|---|
| 1,597 | 381 | 1,154 | 1,240 | 230 | 240 |
| Protein | Taxonomy | varenicline (IC50) | nelfinavir (IC50) |
|---|---|---|---|
| Tyrosine-protein kinase Fyn | Homo sapiens (human) | 7.971 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 8.852 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 3.3938 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 1.275 | |
| ATP-dependent translocase ABCB1 | Mus musculus (house mouse) | 2.3 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 8.852 | |
| Protease | Human immunodeficiency virus 1 | 0.53 | |
| Protease | Human immunodeficiency virus 1 | 0.0054 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
1 review(s) available for varenicline and nelfinavir
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
1 other study(ies) available for varenicline and nelfinavir
| Article | Year |
|---|---|
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |