vantocil has been researched along with biguanides in 494 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (1.62) | 18.7374 |
| 1990's | 47 (9.51) | 18.2507 |
| 2000's | 112 (22.67) | 29.6817 |
| 2010's | 250 (50.61) | 24.3611 |
| 2020's | 77 (15.59) | 2.80 |
| Authors | Studies |
|---|---|
| Dorogova, VB; Lisetskaia, LG | 1 |
| Cavanagh, HD; Ichijima, H; Imayasu, M; Moriyama, T; Ohashi, J | 1 |
| Barker, J; Brown, MR; Collier, PJ; Farrell, I; Gilbert, P | 1 |
| Dart, JK; Kilvington, S; Larkin, DF | 1 |
| Stenhouse, MA | 1 |
| Gilbert, P; Pemberton, D; Wilkinson, DE | 2 |
| Chawner, JA; Gilbert, P | 1 |
| Broxton, P; Gilbert, P; Woodcock, PM | 3 |
| Broxton, P; Gilbert, P; Heatley, F; Woodcock, PM | 1 |
| Ikeda, T; Tazuke, S; Watanabe, M | 1 |
| Bamford, CH; Hann, RA; Ikeda, T; Ledwith, A | 1 |
| Eager, E; Hay, AJ; Kasian, PA; Millis, NF; Pickering, WJ; Tan, MA | 1 |
| Kennedy, JF; Rashid, DH; Roig, MG | 1 |
| Khan, PK; Kumar, D; Sinha, SP | 1 |
| Collum, LM; Devine, P; Hurley, C; Kennedy, SM; Ooi, YS | 1 |
| Daley, TE; Mathers, WD; Sutphin, JE; Winchester, K | 1 |
| Easty, DL; Ruddell, TJ | 1 |
| McAnally, CL; Rosenthal, RA; Schlech, BA; Stein, JM | 1 |
| Hay, J; Kirkness, CM; Seal, DV | 1 |
| Dart, JK; Elder, MJ | 1 |
| Kilvington, S | 1 |
| Cursons, RT; Gray, TB; Gross, KA; Shewan, JF | 1 |
| Bacon, AS; Dart, JK; Ficker, LA; Frazer, DG; Matheson, M; Wright, P | 1 |
| Fiscella, R; Winarko, TK; Yee, E | 1 |
| Mills, RA; Osato, MS; Pyron, M; Wilhelmus, KR | 1 |
| Jensen, HG; Parmley, VC; Rowsey, JJ; Varga, JH; Wolf, TC | 1 |
| Cameron, JD; Holland, EJ; Krachmer, JH; Pfister, DR | 1 |
| Markx, GH; Pethig, R; Zhou, XF | 1 |
| Ahearn, DG; Gabriel, MM; Tirado-Angel, J; Wilson, LA | 1 |
| Burger, DM; Eggink, CA; Sauerwein, RW; Vaandrager, W | 1 |
| Hay, J; Seal, DV | 1 |
| Duguid, R; Lloyd, CH; Thorstensen, AE | 1 |
| Furr, JR; Khunkitti, W; Lloyd, D; Russell, AD | 2 |
| Chandler, JW; Fiscella, RG; Messick, CR; Moshifar, M; Pendland, SL; Viana, M | 1 |
| Belyea, DA; Kramer, KK; Lin, JC; McEvoy, P; Ward, TP | 1 |
| Crawford, GJ; Kumar, B | 1 |
| Essary, LR; Fleming, TP; Garcia-Ferrer, FJ; Goldberg, MA; Laycock, KA; Pepose, JS; Tarle, IS; Valluri, S | 1 |
| Avery, SV; Furr, JR; Khunkitti, W; Lloyd, D; Russell, AD | 1 |
| Allan, BD; Dart, JK; Duguid, IG; Ficker, L; Matheson, M; Morlet, N; Tuft, S | 1 |
| Michel, D; Zäch, GA | 1 |
| Sullivan, L | 1 |
| Chung, DI; Kong, HH | 1 |
| Chen, FK; Lin, SC; Tseng, SH | 1 |
| Bhakoo, M; Das, JR; Gilbert, P; Jones, MV | 1 |
| Cursons, R; Gray, TB; Murdoch, D; Parr, D | 1 |
| Eigenmann, PA; Hauser, C; Olivieri, J | 1 |
| Furr, JR; Hann, AC; Khunkitti, W; Lloyd, D; Russell, AD | 2 |
| Anitha, M; Divya, R; George, C; Prajna, NV; Srinivasan, M | 1 |
| Fiscella, RG; Losnedahl, KJ; Messick, CR; Moshirfar, M; Pendland, SL; Schreckenberger, PC; Schriever, CA | 1 |
| Sheu, MM; Tien, SH | 1 |
| Kramer, A; Müller, G | 3 |
| Ahearn, DG; Avery, SV; Borazjani, RN; May, LL; Noble, JA | 1 |
| Basketter, DA; Brasch, J; Fuchs, T; Geier, J; Pirker, C; Schnuch, A; Schulze-Dirks, A | 1 |
| Buck, SL; Rosenthal, RA; Schlech, BA | 2 |
| Avni, I; Blank-Porat, D; Harizman, N; Keller, N; Wygnanski-Jaffe, T; Wysenbeek, YS | 1 |
| Biswas, NR; Das, GK; Mittal, D; Mohanty, S; Panda, A | 1 |
| Barrón, J; de Fernando, S; Gaztelurrutia, L; López, L; Pérez-Irezábal, J; Vilar, B | 1 |
| Fan, DS; Lam, DS; Lyon, D; Poon, AS; Rao, SK | 1 |
| Barrett, GD; Gajdatsy, AD; Kosmin, A | 1 |
| Bernhardt, O; Kocher, T; Kramer, A; Pitten, FA; Rosin, M; Ruhnau, M; Welk, A | 1 |
| Aspöck, H; Faschinger, C; Haller-Schober, EM; Hiti, K; Walochnik, J | 1 |
| K, LT; Madhavan, HN; Narasimhan, S | 1 |
| Kocher, T; Kramer, A; Majic-Todt, A; Pitten, FA; Rosin, M; Welk, A | 1 |
| Ahearn, DG; Avery, SV; Crow, SA; Noble, JA | 1 |
| Donoso, R; López, M; Mura, JJ | 1 |
| Carrasco, MA; Cosentino, MJ; Cremona, G; Tytiun, A | 1 |
| Mansouri, E; Schmitt-Graeff, A; Schöffel, U; Sendt, W; Wolff-Vorbeck, G | 1 |
| Ahuja, R; Biswas, NR; Khokhar, S; Panda, A; Satpathy, G | 1 |
| Codling, CE; Maillard, JY; Russell, AD | 1 |
| Katsu, T; Ohmizo, C; Yasuda, K | 1 |
| Brancato, R; Matuska, S; Paganoni, G; Rama, P; Spinelli, A; Viganò, M | 1 |
| Anger, C; Brady, N; Graham, R; Simmons, PA; Tran, L; Vehige, JG | 1 |
| Miller, JL; Perfect, JR; Schell, WA; Steinbach, WJ | 1 |
| Dart, JK; Hughes, R; Kilvington, S; Matheson, M; Pérez-Santonja, JJ; Tufail, A | 1 |
| Heaselgrave, W; Hughes, R; Kilvington, S | 1 |
| Hattori, T; Kato, R; Nakata, Y | 1 |
| Geerling, G; Hansmann, F; Kramer, A; Müller, M; Ohgke, H; Strobel, H | 1 |
| Allen, MJ; Morby, AP; White, GF | 2 |
| Furr, JR; Lloyd, D; Russell, AD; Turner, NA | 1 |
| Lim, L; Wei, RH | 1 |
| Blom, K; Davoudi, M; Mörgelin, M; Nitsche, DP; Schmidtchen, A; Sonesson, A; Werthén, M | 1 |
| Corbett, LQ; Milne, CT; Motta, GJ | 1 |
| Seal, D | 1 |
| Baudrimont, M; Bonnel, S; Borderie, V; Bourcier, T; Chaumeil, C; Laroche, L; Patteau, F; Rondeau, N | 1 |
| Motta, GJ; Trigilia, D | 1 |
| Kocher, T; Kramer, A; Rosin, M; Schmidt-Martens, G; Schwahn, Ch; Splieth, CH; Welk, A | 1 |
| Chang, CY; Hulka, GF; Perfect, JR; Schell, WA | 1 |
| Carey, C; Dassanayake, N; David, R; Garofalo, RJ; Stein, J; Stone, R | 1 |
| Ahlstrom, L; Mills, PC; Wilson, WJ | 1 |
| Ferguson, ML; Krebs, FC; Labib, M; Miller, SR; Rando, RF; Wigdahl, B | 1 |
| Dissemond, J; Franckson, T; Goos, M; Hoeft, D; Knab, J; Kroger, K | 1 |
| Dissemond, J; Grabbe, S; Graue, N | 1 |
| Hall, KE; Holah, JT | 1 |
| Fleck, CA | 1 |
| Aspöck, H; Faschinger, C; Hiti, K; Maria Haller-Schober, E; Walochnik, J | 1 |
| Collins, AN; O'Malley, LP; White, GF | 1 |
| Ballet, JJ; Benichou, J; Brasseur, G; Duclos, C; Favennec, L; François, A; Gargala, G; Hellot, MF; Muraine, M; Vasseneix, C | 1 |
| Exarchou, AM; Gartaganis, SP; Georgakopoulos, CD | 1 |
| Bettag, C; Fabry, W; Handschin, AE; Hillmeier, J; Huber, FX; Kock, HJ; Lettgen, B; Trampenau, C | 1 |
| Estudillo Pérez, V; Fernández Mansilla, M; Gómez Ferrero, O; Salas Campos, L | 1 |
| Balguerie, X; Caillard, JF; Gehanno, JF; Priot, AE | 1 |
| Illingworth, CD; Niyadurupola, N | 1 |
| Dayanir, V; Ertabaklar, H; Ertuğ, S; Türk, M; Walochnik, J | 1 |
| Dassanayake, NL; Meadows, DL; Rosenthal, RA; Schlech, BA; Schlitzer, RL; Stone, RP | 1 |
| Frieling, H; Gründling, M; Kanellopoulou, T; Lauer, KS; Lehmann, C; Meissner, K; Pavlovic, D; Usichenko, T; Wendt, M | 1 |
| Chung, DI; Jeong, HJ; Kong, HH; Lee, JE; Lee, JS; Lee, SJ; Ock, MS; Xuan, YH; Yu, HS | 1 |
| Deland, PN; Edrington, TB; Marsden, HJ; Paugh, JR; Simmons, PA; Vehige, JG | 1 |
| Acierno, MJ; Adamson, TW; Bauer, RW; Mitchell, MA; Roundtree, MK; Singleton, CB | 1 |
| Dick, B; Kramann, C; Petry, F; Pfeiffer, N; Stemberger, K; Thieme, H; Weber, A | 1 |
| Santodomingo-Rubido, J | 1 |
| Basketter, DA; Geier, J; Jowsey, IR; Schnuch, A; Uter, W | 1 |
| Eulert, J; Hendrich, C; Ince, A; Jakob, F; Löhr, JF; Schütze, N | 1 |
| Choi, HY; Hahn, TW; Lee, JE; Lee, JS; Oum, BS; Yu, HS | 1 |
| Ayadi, A; Ben Salah, S; Ben Zina, Z; Cheikrouhou, F; Colin, J; Feki, J; Makni, F; Mlik, M | 1 |
| Cetin, A; Polat, ZA; Vural, A | 1 |
| Choi, SH; Chung, DI; Jeong, HJ; Kim, JH; Kong, HH; Lee, KH; Lee, SJ; Ock, MS; Park, SK; Xuan, YH; Yu, HS | 1 |
| Jowsey, IR | 1 |
| Ayres, BD; Cohen, EJ; Eagle, RC; Hammersmith, KM; Laibson, PR; Rapuano, CJ; Rocha, FN; Thebpatiphat, N | 1 |
| Choi, HY; Lee, JE; Lee, JS; Oum, BS; Yu, HS | 1 |
| Levy, B | 1 |
| Assadian, O; Bruck, JC; Daeschlein, G; Koch, S; Kramer, A; Meinl, C | 1 |
| Bhui, RD; Kocatürk, T; Pineda, R | 1 |
| Collins, AN; O'Malley, LP; Shaw, CH | 1 |
| Dissemond, J; Grabbe, S; Körber, A; Rietkötter, J | 1 |
| Chi, SC; Lam, DS; Wong, VW | 1 |
| Bunce, C; Ficker, L; Fraenkel, G; Goh, D; Lim, N; Poole, TR; Xing, W | 1 |
| Choi, SH; Hahn, TW; Lee, JE; Lee, JS; Yu, HS | 1 |
| Baudouin, C; Dutot, M; Rat, P; Warnet, JM | 1 |
| de Hoog, GS; Goudswaard, WB; Kampinga, GA; Kooijman, CM; Reijnen, MM | 1 |
| Cavanagh, HD; Imayasu, M; Ohashi, Y; Shimada, S; Shiraishi, A | 1 |
| Kuwabara, Y; Ueda, S | 1 |
| Blanke, M; Brem, MH; Gusinde, J; Hennig, FF; Mueller, O; Olk, A; Schmidt, J | 1 |
| Hattori, T; Masadome, T; Takano, M; Yamagishi, Y | 1 |
| Herz, NL; Matoba, AY; Wilhelmus, KR | 1 |
| de Menezes, JA; de Morais, MA; Elsztein, C | 1 |
| Hsiao, CH; Huang, SC; Lin, HC; Lin, MY; Ma, DH; Tan, HY; Yeh, LK | 1 |
| Gilbert, P; Ledder, RG; McBain, AJ; Moore, LE | 1 |
| Perucho, NS; Valenzuela, AR | 1 |
| Booton, GC; Joslin, CE; Shoff, ME; Sugar, J; Tu, EY | 1 |
| Geraldo, IM; Gilman, A; Modak, SM; Shintre, MS | 1 |
| Gordon, YJ; Kowalski, RP; Shanks, RM; Thompson, PP | 1 |
| Das, S; Sahu, SK; Sharma, S; Vemuganti, GK | 2 |
| Chung, BS; Chung, DI; Hahn, TW; Hong, YC; Kong, HH; Xuan, YH | 1 |
| Krebsbach, LE; Mueller, SW | 1 |
| Dissemond, J; Klode, J; Körber, A | 1 |
| Lorente Fernández, G; Rodríguez Cancio, MC; Verdú Moresco, A | 1 |
| Hunt, C; Keir, N; Woods, CA; Young, G | 1 |
| Benzie, IF; Boost, MV; Cho, P; Choy, CK | 1 |
| Kim, EC; Kim, MS | 2 |
| Lipener, C | 1 |
| Kuznetsov, NA; Mil'chakov, AA; Nikitin, VG; Teleshova, EB | 1 |
| McGhee, C; McKelvie, J; Patel, D | 1 |
| Apruzzese, M; Cantatore, A; Guerriero, S; La Tegola, MG; Monno, R | 1 |
| McIntosh, C; Ousey, K | 1 |
| Goertz, O; Hirsch, T; Jacobsen, F; Niederbichler, A; Rittig, A; Seipp, HM; Steinau, HU; Steinstraesser, L | 1 |
| Gordon, EA; Lucas, AD; Stratmeyer, ME | 1 |
| Badenoch, PR; Chang, JH; Coster, DJ; Klebe, S; Mills, RA; Sadlon, TA | 1 |
| Denyer, SP; Maillard, JY; McGeechan, P; Pinto, F | 1 |
| Denyer, SP; Maillard, JY; Pinto, F | 1 |
| Abels, C; Daigeler, A; Goertz, O; Hirsch, T; Knie, U; Langer, S; May, T; Steinau, HU | 1 |
| Degerbeck, F; Jakob, T; Kautz, O; Schumann, H; Venemalm, L | 1 |
| Anders, S; Beckmann, J; Grifka, J; Handel, M; Kalteis, T; Rath, B; Schaumburger, J; Springorum, HR | 1 |
| Beral, L; Desbois, N; Donnio, A; Guyomarch, J; Merle, H; Olive, C; Theodose, R; van Nuoï, DN | 1 |
| Bandamwar, KL; Cheung, D; Garrett, Q; Huang, J; Lee, L; Ng, C; Papas, EB | 1 |
| Carnt, N; de la Jara, PL; Diec, J; Evans, V; Harmis, N; Holden, BA; Iskandar, S; Naduvilath, T; Stapleton, F; Willcox, MD | 1 |
| Das, S; Kar, S; Nayak, SS; Sahu, SK; Sharma, S | 2 |
| Filipuzzi-Jenny, E; Kulik, EM; Rohrer, N; Walter, C; Waltimo, T; Weiger, R; Widmer, AF | 1 |
| Bender, C; Ekkernkamp, A; Hammann, A; Hartmann, B; Hinz, P; Huebner, NO; Kindel, E; Koban, I; Koch, S; Kohlmann, T; Kramer, A; Lademann, J; Matthes, R; Müller, G; Titze, R; Weltmann, KD | 1 |
| Dissemond, J; Eberlein, T; Gerber, V; Kramer, A; Riepe, G; Strohal, R; Vasel-Biergans, A | 1 |
| Hartmann, B; Maier, H; Ottomann, C; Schaden, W; Stojadinovic, A; Thiele, R; Tyler, J | 1 |
| Assadian, O; Hübner, NO; Kramer, A; Mulder, G | 1 |
| Brill, FH; Roth, B | 1 |
| Kaehn, K | 1 |
| Hübner, NO; Kramer, A | 1 |
| Bender, C; Hübner, NO; Kindel, E; Koban, I; Kocher, T; Kramer, A; Matthes, R; Müller, G; Rändler, C | 1 |
| Beule, AG; Hosemann, W; Kohlmann, T; Kramer, A; Roth, C; Scharf, C | 1 |
| Barbanera, S; Bertone, MS; Dini, V; Romanelli, M | 1 |
| Assadian, O; Eberlein, T | 1 |
| Behrens, A; Castro-Combs, JM; Flikier, D; Kalyani, S; Kashiwabuchi, RT; Khan, YA; Martins, SA; Stanley, P | 1 |
| Fonn, D; Jones, L; Peterson, RC; Woods, CA | 1 |
| Catalone, BJ; Ferguson, ML; Howett, MK; Kholodovych, V; Kish-Catalone, T; Krebs, FC; Labib, M; Passic, SR; Rando, R; Welsh, W; Wigdahl, B; Zhu, W | 1 |
| Becerro de Bengoa Vallejo, R; Cervera, LA; Fernández, DS; Losa Iglesias, ME; Prieto, JP | 1 |
| Alvarez-Lorenzo, C; Bromberg, L; Chang, EP; Concheiro, A; Hatton, TA; Magariños, B | 1 |
| Sanjay, S | 1 |
| Goertz, O; Hirsch, T; Jacobsen, F; Lahmer, A; Limoochi-Deli, S; Seipp, HM; Steinau, HU; Steinstraesser, L | 1 |
| Arnholdt, J; Kolar, P; Matziolis, G; Perka, C; Röhner, E; Seeger, JB; Thiele, K | 1 |
| Coutts, P; Sibbald, RG; Woo, KY | 1 |
| Mori, O; Nishida, T; Toyohara, M; Ueda, K; Yanai, R | 1 |
| Ohashi, Y | 1 |
| Chihara, H; Inatomi, T; Kinoshita, S; Sasaki, M; Shiota, T; Sotozono, C; Ueta, M; Yokoi, N | 1 |
| Andriessen, A; Drummer, N; Pallua, N; Piatkowski, A; Ulrich, D | 1 |
| Harden, D; Koburger, T; Kramer, A; Müller, G; Schmitt, J | 1 |
| Frenzel, E; Niederweis, M; Schmidt, S; Steinhauer, K | 1 |
| Daigeler, A; Goertz, O; Hirsch, T; Homann, HH; Lehnhardt, M; Ring, A; Steinau, HU | 1 |
| Hall, JQ; Krall, D; Meadows, DL; Nguyen, AL; Paugh, JR; Ramsey, AC; Webb, JR | 1 |
| Assadian, O; Dissemond, J; Eberlein, T; Gerber, V; Kingsley, A; Kramer, A; Leaper, DJ; Mosti, G; Piatkowski de Grzymala, A; Riepe, G; Risse, A; Romanelli, M; Strohal, R; Traber, J; Vasel-Biergans, A; Wild, T | 1 |
| Hotz, D; Läuchli, S; Mayer, D; Roth, B; Traber, J | 1 |
| Becker, R; Fleischmann, W; Jukema, GN; Lehner, B | 1 |
| Dähn-Wollenberg, S; Hoff, P; Matziolis, G; Perka, C; Röhner, E; Seeger, JB | 1 |
| Alblas, JG; Andriessen, A; Elzinga, G; Klicks, RJ; Post, A; Spits, H; van Doorn, J; van Gent, M; Wiersema, AM | 1 |
| Obwaller, A; Polat, ZA; Vural, A; Walochnik, J | 1 |
| Gannon, FH; Hartmann, B; Heggeness, MH; Lavin, PT; Ottomann, C; Schaden, W; Stojadinovic, A; Thiele, R | 1 |
| Hattori, T; Masadome, T; Miyanishi, T; Ueda, H; Watanabe, K | 1 |
| Chua, YP; Lee, CK; Saw, A | 1 |
| Afshari, NA; Goldhagen, BE; Majka, CP; Perfect, JR; Rebong, RA; Santaella, RM; Steinbach, WJ | 1 |
| de Lucena, RM; de Morais, MA; Elsztein, C | 1 |
| Cavanagh, HD; Hori, Y; Imayasu, M; Tchedre, KT | 1 |
| Andreas, K; Buttgereit, F; Hoff, P; Matziolis, G; Perka, C; Pfitzner, T; Preininger, B; Röhner, E; Seeger, JB | 1 |
| Lucas, AD | 1 |
| Brey, EM; Drapala, PW; Jiang, B; Kang-Mieler, JJ; Larson, JC; Pérez-Luna, VH | 1 |
| Andriessen, A; Bruckner, M; Eberlein, T; Payrich, M; Schwarz, C; Wild, T | 1 |
| Boost, MV; Cho, P; Choy, CK | 1 |
| Andriessen, A; Lenselink, E | 1 |
| Abel, M; Eberlein, T; Gruber Moesenbacher, U; Haemmerle, G; Mittlboeck, M; Signer, M; Strohal, R; Traber, J | 1 |
| Kobayashi, T; Mito, T; Ohashi, Y; Shiraishi, A; Suzuki, T; Watanabe, N | 1 |
| Awasthi, AK; Bright, FV; Kraut, ND; Liu, XM; Maziarz, EP; Merchea, MM | 1 |
| Gao, Y; Lin, T; Liu, X; Tang, Y; Wang, H; Wang, X; Zhao, Y | 1 |
| Behr, B; Daigeler, A; Goertz, O; Hirsch, T; Kolbenschlag, J; Lehnhardt, M | 1 |
| Behrens-Baumann, W; Haeberle, H; Hofmüller, W; Seibold, M; Tammer, I; Tintelnot, K; Walter, S; Wecke, T | 1 |
| Bernier, AM; Boisvert, A; De Moissac, D; Dickman, M; Diop, L; Oulé, MK; Quinn, K; Rondeau, S | 1 |
| Buschmann, HJ; Finger, S; Hipler, UC; Wiegand, C | 2 |
| Alou Cervera, L; Becerro de Bengoa Vallejo, R; Losa Iglesias, ME; Prieto Prieto, J; Sevillano Fernández, D | 1 |
| Assadian, O; Bender, CP; Hübner, NO; Koban, I; Kramer, A | 1 |
| Andrée, S; Brill, FH; Egli-Gany, D; Hintzpeter, M; Pavel, V | 1 |
| Andriessen, A; Nielsen, AM | 1 |
| Arnalich-Montiel, F; Irigoyen, C; López-Vélez, R; Lorenzo-Morales, J; Morcillo-Laiz, R; Muñoz-Negrete, F; Piñero, JE; Valladares, B | 1 |
| Buttgereit, F; Hoff, P; Matziolis, G; Perka, C; Pfitzner, T; Röhner, E; Seeger, JB | 1 |
| Chilson, G; Minnich, KE; Pritt, SL; Stolarick, R; Unverdorben, M; Wilkins, RG | 1 |
| Ashar, JN; Garg, P; Mathur, A; Nalamada, S; Taneja, M | 1 |
| Brown, JN; Eydelman, MB; Hitchins, VM; Lucas, AD; Shoff, ME | 1 |
| Chaput, MP; Clavet, CR; Eydelman, MB; Hitchins, VM; Lucas, AD; Shoff, ME; Silverman, MD; Striplin, M | 1 |
| Borderie, VM; Bouheraoua, N; Chaumeil, C; Gaujoux, T; Goldschmidt, P; Laroche, L | 1 |
| Carville, K; Drake, R; Fletcher, J; Leaper, DJ; Schultz, G; Swanson, T | 1 |
| Czaika, V; Kramer, A; Lademann, J; Müller, G; Patzelt, A; Richter, H; Sterry, W; Ulmer, M; Vergou, T | 1 |
| Adt, I; Chadeau, E; Degraeve, P; Dumas, E; Girodet, C; Noël, C; Oulahal, N | 1 |
| Bavetta, F; Di Renzo, GC; Gerli, S | 1 |
| Koburger, T; Kramer, A; Müller, G | 1 |
| Bader, RD; Badreldin, AM; Hekmat, K | 1 |
| Ernst, D; Fabry, W; Jethon, F; Kock, HJ | 1 |
| Fan, SL; Findlay, A; Punzalan, S; Serrano, C | 1 |
| Böer, U; Harder, M; Haverich, A; Jonigk, D; Klingenberg, M; Kreipe, HH; Spengler, C; Wilhelmi, M | 1 |
| Baier, G; Cavallaro, A; Landfester, K; Mailänder, V; Musyanovych, A; Vasilev, K | 1 |
| Andrew, N; Badenoch, PR; Chehade, M; Sadlon, TA; van Zyl, LM | 1 |
| Kowalski, RP; Mah, FS; O'Connor, KE; Romanowski, EG; Shanks, RM; Yates, KA | 1 |
| Dilamian, M; Masoumi, J; Montazer, M | 1 |
| Arici, MK; Dursun, A; Obwaller, A; Polat, ZA; Vural, A; Walochnik, J | 1 |
| Assadian, O; Cutting, KF; Dosch, V; Forstner, C; Kramer, A; Leaper, DJ; Leitgeb, J; Schuster, R | 1 |
| Anderson, MJ; Parks, PJ; Peterson, ML; Scholz, MT | 1 |
| Banovic, F; Bozic, F; Lemo, N | 1 |
| Guyver, PM; Jeffery, SL; Mountain, AJ | 1 |
| Levin, F; Servat, J; Yun, SH | 1 |
| Capriglione, P; Cennamo, G; Cerulli, L; Del Prete, S; Di Cave, D; Pesce, G; Rusciano, G; Sasso, A | 1 |
| Abdel Aziz, S; Kowalski, RP; Nau, AC; Raju, LV; Romanowski, EG; Shanks, RM | 1 |
| Dobrindt, O; Matziolis, G; Perka, C; Röhner, E; Vörös, P; Windisch, C | 1 |
| Hauser-Gerspach, I; Krastl, G; Waltimo, T; Weiger, R; Zaugg, LK; Zitzmann, NU | 1 |
| Jansen, B; Kohnen, W; Peivandi, AA; Schmidt, FP | 1 |
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32 review(s) available for vantocil and biguanides
| Article | Year |
|---|---|
Methods used to evaluate the effectiveness of contact lens care solutions and other compounds against Acanthamoeba: a review of the literature.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Animals; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Contact Lens Solutions; Contact Lenses; Drug Evaluation; Humans; Hydrogen Peroxide; Thimerosal | 2000 |
[Keratitis caused by Acanthamoeba spp.: presentation of 10 cases].
Topics: Acanthamoeba; Adolescent; Adrenal Cortex Hormones; Adult; Amebiasis; Amebicides; Animals; Biguanides; Contact Lens Solutions; Contact Lenses; Corneal Transplantation; Drug Contamination; Equipment Contamination; Female; Humans; Keratitis; Ketoconazole; Male; Middle Aged; Neomycin; Retrospective Studies; Spain; Treatment Outcome | 2000 |
Scedosporium prolificans osteomyelitis in an immunocompetent child treated with voriconazole and caspofungin, as well as locally applied polyhexamethylene biguanide.
Topics: Administration, Topical; Anti-Bacterial Agents; Antifungal Agents; Biguanides; Caspofungin; Child, Preschool; Disinfectants; Echinocandins; Humans; Lipopeptides; Magnetic Resonance Imaging; Male; Mucormycosis; Osteomyelitis; Peptides; Peptides, Cyclic; Pyrimidines; Scedosporium; Triazoles; Voriconazole | 2003 |
Treatment of Acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Amebicides; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antiprotozoal Agents; Benzamidines; Biguanides; Chlorhexidine; Contact Lenses; Humans; Neomycin; Phosphorylcholine; Treatment Failure | 2003 |
Fighting infection in chronic wounds.
Topics: Acrylic Resins; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bandages; Benchmarking; Biguanides; Biofilms; Body Burden; Chronic Disease; Colony Count, Microbial; Disinfectants; Humans; Infection Control; Iodine Compounds; Iodophors; Patient Selection; Silver Compounds; Skin Care; Wound Infection | 2006 |
Proactive surveillance of contact allergies: an important component of the risk management strategy for skin sensitizers.
Topics: Allergens; Biguanides; Dermatitis, Allergic Contact; Disinfectants; Dose-Response Relationship, Drug; Environmental Exposure; Environmental Monitoring; Europe; Humans; Research Design; Risk Assessment; Skin; Skin Tests | 2007 |
Acanthamoeba keratitis presenting as a plaque.
Topics: Acanthamoeba Keratitis; Atropine; Biguanides; Ciprofloxacin; Cornea; Diagnosis, Differential; Drug Administration Schedule; Drug Therapy, Combination; Eye Infections, Fungal; Female; Humans; Middle Aged; Ophthalmic Solutions | 2008 |
Polihexanide: a safe and highly effective biocide.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bacteria; Biguanides; Biofilms; Disinfectants; Drug Delivery Systems; Drug Resistance, Microbial; Drug Resistance, Multiple; Humans; Pseudomonas aeruginosa; Skin; Staphylococcus aureus; Wound Infection | 2010 |
Review on the efficacy, safety and clinical applications of polihexanide, a modern wound antiseptic.
Topics: Adsorption; Animals; Anti-Infective Agents, Local; Biguanides; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Skin; Wound Healing; Wound Infection | 2010 |
Clinical use of polihexanide on acute and chronic wounds for antisepsis and decontamination.
Topics: Anti-Infective Agents, Local; Antisepsis; Biguanides; Debridement; Decontamination; Humans; Therapeutic Irrigation; Time Factors; Treatment Outcome; Wound Healing | 2010 |
[Recommendations for the use of polyhexanide-containing products for the treatment of wounds].
Topics: Anti-Infective Agents, Local; Biguanides; Consensus; Critical Pathways; Humans; Wound Infection | 2011 |
[Skin antiseptics in plastic surgery].
Topics: Anti-Infective Agents, Local; Biguanides; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enterococcus faecalis; Escherichia coli; Humans; Imines; Microbial Sensitivity Tests; Plastic Surgery Procedures; Povidone-Iodine; Pseudomonas aeruginosa; Pyridines; Staphylococcal Infections; Surgical Wound Infection; Wound Healing | 2012 |
Extending the TIME concept: what have we learned in the past 10 years?(*).
Topics: Abbreviations as Topic; Anti-Bacterial Agents; Anti-Infective Agents, Local; Anxiety; Bandages; Biguanides; Biofilms; Debridement; Disinfectants; Disinfection; Drug Resistance, Bacterial; Electromagnetic Fields; Exudates and Transudates; Honey; Humans; Hyperbaric Oxygenation; Infections; Inflammation; Iodophors; Laser Therapy; Negative-Pressure Wound Therapy; Oxygen Inhalation Therapy; Pain Management; Silver Compounds; Silver Sulfadiazine; Stress, Psychological; Ultrasonic Therapy; Wound Healing; Wounds and Injuries | 2012 |
Diabetic foot wounds: the value of negative pressure wound therapy with instillation.
Topics: Anti-Bacterial Agents; Biguanides; Chondroitin Sulfates; Collagen; Debridement; Diabetic Foot; Granulation Tissue; Humans; Negative-Pressure Wound Therapy; Skin, Artificial; Therapeutic Irrigation; Wound Healing; Wound Infection | 2013 |
Recommendations on negative pressure wound therapy with instillation and antimicrobial solutions - when, where and how to use: what does the evidence show?
Topics: Acetic Acid; Anti-Infective Agents, Local; Biguanides; Cross Infection; Evidence-Based Medicine; Humans; Negative-Pressure Wound Therapy; Povidone-Iodine; Surgical Wound Infection; Therapeutic Irrigation; Wound Infection; Wounds and Injuries | 2013 |
Dressings for the prevention of surgical site infection.
Topics: Bandages; Bandages, Hydrocolloid; Biguanides; Humans; Randomized Controlled Trials as Topic; Surgical Wound Infection; Wound Healing | 2014 |
Medical interventions for acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Humans; Randomized Controlled Trials as Topic | 2015 |
Polyhexanide - safety and efficacy as an antiseptic.
Topics: Anti-Infective Agents, Local; Biguanides; Candida albicans; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; In Vitro Techniques; Wound Infection | 2016 |
The Development of Drugs against Acanthamoeba Infections.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Amphotericin B; Animals; Antiprotozoal Agents; Azoles; Biguanides; Caspofungin; Cefazolin; Chlorhexidine; Echinocandins; Humans; Infectious Encephalitis; Lipopeptides; Meropenem; Natamycin; Polymyxin B; Thienamycins | 2016 |
The Effectiveness of Topical Polyhexamethylene Biguanide (PHMB) Agents for the Treatment of Chronic Wounds: A Systematic Review.
Topics: Anti-Bacterial Agents; Biguanides; Humans; Methicillin-Resistant Staphylococcus aureus; Pain Management; Randomized Controlled Trials as Topic; Wound Healing | 2016 |
Dacryoadenitis and extraocular muscle inflammation associated with contact lens-related Acanthamoeba keratitis: A case report and review of the literature.
Topics: Acanthamoeba Keratitis; Adult; Anti-Bacterial Agents; Antiprotozoal Agents; Benzamidines; Biguanides; Contact Lenses; Dacryocystitis; Drug Therapy, Combination; Eye Infections, Parasitic; Fluoroquinolones; Gentamicins; Humans; Magnetic Resonance Imaging; Male; Microscopy, Confocal; Moxifloxacin; Oculomotor Muscles; Orbital Myositis | 2017 |
Dressings for the prevention of surgical site infection.
Topics: Alginates; Bandages; Bandages, Hydrocolloid; Biguanides; Disinfectants; Humans; Randomized Controlled Trials as Topic; Silver; Surgical Wound Infection; Wound Healing | 2016 |
Evidence-Based Review of Antibiofilm Agents for Wound Care.
Topics: Animals; Anti-Infective Agents, Local; Bandages; Benzalkonium Compounds; Biguanides; Biofilms; Disinfectants; Honey; Humans; Hypochlorous Acid; Iodophors; Low-Level Light Therapy; Surface-Active Agents; Ultrasonic Therapy; Wound Healing; Wound Infection | 2021 |
Addressing the challenges in antisepsis: focus on povidone iodine.
Topics: Anti-Infective Agents, Local; Bacteria; Bacterial Infections; Biguanides; Biofilms; Chlorhexidine; Humans; Imines; Povidone-Iodine; Pyridines; Wound Healing | 2020 |
Wound bed preparation: a case series using polyhexanide and betaine solution and gel-a UK perspective.
Topics: Administration, Cutaneous; Betaine; Biguanides; Gels; Humans; Pressure Ulcer; State Medicine; Therapeutic Irrigation; United Kingdom; Wound Healing | 2020 |
Nanoparticles based therapeutic efficacy against Acanthamoeba: Updates and future prospect.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Amebiasis; Amebicides; Biguanides; Central Nervous System Protozoal Infections; Chlorhexidine; Drug Delivery Systems; Immunocompetence; Immunocompromised Host; Infectious Encephalitis; Nanoparticles; Trophozoites | 2020 |
Pressure Injury Prevention and Treatment in Critically Ill Children.
Topics: Age Factors; Biguanides; Child; Child Development; Critical Illness; Disinfectants; Humans; Hydrogels; Intensive Care Units, Pediatric; Patient Positioning; Pressure Ulcer | 2020 |
Wound cleansing for treating venous leg ulcers.
Topics: Aged; Anti-Infective Agents, Local; Betaine; Bias; Biguanides; Confidence Intervals; Detergents; Disinfectants; Ethylene Glycols; Female; Humans; Hydrogen Peroxide; Imines; Male; Middle Aged; Pain Measurement; Pyridines; Randomized Controlled Trials as Topic; Ringer's Solution; Saline Solution; Varicose Ulcer; Wound Healing | 2021 |
Evidence-Based Wound Irrigation: Separating Fact from Fiction.
Topics: Biguanides; Evidence-Based Medicine; Humans; Intraoperative Care; Negative-Pressure Wound Therapy; Povidone-Iodine; Practice Guidelines as Topic; Soft Tissue Injuries; Surgical Wound Infection; Therapeutic Irrigation; Treatment Outcome; Wound Healing | 2021 |
Combined Phialemonium curvatum and Acanthamoeba Keratitis: The Importance of Early Diagnosis and Specific Therapy.
Topics: Acanthamoeba Keratitis; Administration, Ophthalmic; Anti-Bacterial Agents; Antifungal Agents; Ascomycota; Biguanides; Disinfectants; Drug Therapy, Combination; Early Diagnosis; Eye Infections, Fungal; Female; Humans; Keratitis; Microscopy, Confocal; Middle Aged; Moxifloxacin; Mycoses; Ophthalmic Solutions; Slit Lamp Microscopy; Voriconazole | 2021 |
Polyhexamethylene biguanide and its antimicrobial role in wound healing: a narrative review.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biguanides; Humans; Wound Healing | 2023 |
Efficacy of Polyhexamethylene Biguanide in Reducing Post-Operative Infections: A Systematic Review and Meta-Analysis.
Topics: Anti-Infective Agents; Biguanides; Humans; Postoperative Complications | 2023 |
62 trial(s) available for vantocil and biguanides
| Article | Year |
|---|---|
Effect of a polyhexamethylene biguanide mouthrinse on bacterial counts and plaque.
Topics: Adult; Analysis of Variance; Bacteria; Biguanides; Chlorhexidine; Colony Count, Microbial; Cross-Over Studies; Dental Disinfectants; Dental Plaque; Dental Plaque Index; Double-Blind Method; Female; Humans; Male; Mouth Mucosa; Mouthwashes; Reproducibility of Results; Statistics, Nonparametric | 2001 |
The effect of a polyhexamethylene biguanide mouthrinse compared to an essential oil rinse and a chlorhexidine rinse on bacterial counts and 4-day plaque regrowth.
Topics: Adult; Analysis of Variance; Anti-Infective Agents, Local; Bacteria; Biguanides; Chlorhexidine; Colony Count, Microbial; Cross-Over Studies; Dental Plaque; Double-Blind Method; Drug Combinations; Female; Humans; Male; Mouth Mucosa; Mouthwashes; Normal Distribution; Oils, Volatile; Placebos; Reproducibility of Results; Salicylates; Statistics as Topic; Terpenes; Tooth | 2002 |
[Polyhexamethylbiguanid (PHMB) as preoperative antiseptic for cataract surgery].
Topics: Adult; Biguanides; Cataract Extraction; Colony-Forming Units Assay; Conjunctiva; Disinfectants; Double-Blind Method; Female; Humans; Isotonic Solutions; Male; Povidone-Iodine; Preoperative Care; Ringer's Lactate; Treatment Outcome | 2004 |
Impact of antimicrobial gauze on bacterial colonies in wounds that require packing.
Topics: Aged; Aged, 80 and over; Bandages; Biguanides; Colony Count, Microbial; Diabetic Foot; Disinfectants; Female; Humans; Male; Middle Aged; Pressure Ulcer; Prospective Studies; Wound Healing; Wounds and Injuries | 2004 |
The effect of an antimicrobial drain sponge dressing on specific bacterial isolates at tracheostomy sites.
Topics: Adult; Aged; Aged, 80 and over; Bandages; Biguanides; Clinical Nursing Research; Disinfectants; Enterobacter cloacae; Enterobacteriaceae Infections; Female; Humans; Infection Control; Male; Methicillin Resistance; Middle Aged; Prospective Studies; Pseudomonas aeruginosa; Pseudomonas Infections; Rehabilitation Centers; Skin; Skin Care; Staphylococcal Infections; Staphylococcus aureus; Time Factors; Tracheostomy; Treatment Outcome; Wound Infection | 2005 |
The effect of a polyhexamethylene biguanide mouthrinse compared with a triclosan rinse and a chlorhexidine rinse on bacterial counts and 4-day plaque re-growth.
Topics: Adult; Analysis of Variance; Anti-Infective Agents, Local; Bacteria; Benzoates; Biguanides; Chlorhexidine; Colony Count, Microbial; Cross-Over Studies; Dental Plaque; Dental Plaque Index; Double-Blind Method; Female; Humans; Male; Maleates; Mouth Mucosa; Mouthwashes; Polyethylenes; Reproducibility of Results; Sodium Dodecyl Sulfate; Triclosan | 2005 |
Corneal staining and subjective symptoms with multipurpose solutions as a function of time.
Topics: Biguanides; Contact Lens Solutions; Contact Lenses, Hydrophilic; Cornea; Cross-Over Studies; Double-Blind Method; Equipment Design; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Pilot Projects; Preservatives, Pharmaceutical; Silicones; Staining and Labeling; Time Factors | 2005 |
Ototoxicity and tolerance assessment of a TrisEDTA and polyhexamethylene biguanide ear flush formulation in dogs.
Topics: Administration, Topical; Animals; Biguanides; Chemistry, Pharmaceutical; Disinfectants; Dogs; Edetic Acid; Evoked Potentials, Auditory, Brain Stem; Female; Hearing Tests; Male; Treatment Outcome; Tympanic Membrane | 2005 |
Bacterial decontamination of surgical wounds treated with Lavasept.
Topics: Bacterial Infections; Biguanides; Colony Count, Microbial; Disinfectants; Double-Blind Method; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Isotonic Solutions; Ringer's Solution; Soft Tissue Infections; Staphylococcus aureus; Surgical Wound Infection; Treatment Outcome; Wound Healing | 2006 |
A pre-application drop containing carboxymethylcellulose can reduce multipurpose solution-induced corneal staining.
Topics: Adult; Biguanides; Carboxymethylcellulose Sodium; Contact Lens Solutions; Contact Lenses, Extended-Wear; Cornea; Corneal Diseases; Cross-Over Studies; Female; Follow-Up Studies; Humans; Male; Ophthalmic Solutions; Refractive Errors; Treatment Outcome | 2007 |
Evaluation of a combination of sodium hypochlorite and polyhexamethylene biguanide as an egg wash for red-eared slider turtles (Trachemys scripta elegans) to suppress or eliminate Salmonella organisms on egg surfaces and in hatchlings.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Egg Shell; Gentamicins; Ovum; Salmonella; Sodium Hypochlorite; Turtles | 2007 |
The comparative clinical performance of a new polyhexamethylene biguanide- vs a polyquad-based contact lens care regime with two silicone hydrogel contact lenses.
Topics: Adolescent; Adult; Biguanides; Contact Lens Solutions; Contact Lenses; Disinfectants; Humans; Hydrogels; Middle Aged; Patient Satisfaction; Polymers; Silicone Gels | 2007 |
Feasibility and clinical applicability of polihexanide for treatment of second-degree burn wounds.
Topics: Adolescent; Adult; Anti-Infective Agents, Local; Biguanides; Burns; Epithelium; Female; Humans; Male; Middle Aged; Povidone-Iodine; Silver Nitrate; Skin Transplantation; Wound Healing | 2007 |
Comparison of polyhexamethylene biguanide and chlorhexidine as monotherapy agents in the treatment of Acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Adult; Biguanides; Chlorhexidine; Disinfectants; Double-Blind Method; Female; Humans; Male; Ophthalmic Solutions; Prospective Studies; Treatment Outcome; Visual Acuity | 2008 |
[The effectiveness of a 0.1% polyhexanide gel].
Topics: Administration, Topical; Biguanides; Debridement; Gels; Health Policy; Humans; Pressure Ulcer; Treatment Outcome; Wounds and Injuries | 2008 |
A randomized clinical comparison of OPTI-FREE EXPRESS and ReNu MultiPLUS multipurpose lens care solutions.
Topics: Adolescent; Adult; Aged; Biguanides; Brazil; Conjunctivitis; Contact Lens Solutions; Cornea; Cross-Over Studies; Double-Blind Method; Female; Humans; Hyperemia; Male; Middle Aged; Patient Satisfaction; Polymers; Propylamines; Statistics, Nonparametric; Surveys and Questionnaires; Xerophthalmia | 2009 |
Clinical safety and efficacy of a novel thermoreversible polyhexanide-preserved wound covering gel.
Topics: Adult; Aged; Anti-Infective Agents, Local; Bandages; Biguanides; Female; Gels; Humans; Informed Consent; Male; Middle Aged; Ointments; Patient Selection; Safety; Silver Sulfadiazine; Skin Transplantation; Viscosity; Wounds and Injuries | 2010 |
Onset time course of solution induced corneal staining.
Topics: Adolescent; Adult; Biguanides; Contact Lens Solutions; Contact Lenses, Hydrophilic; Cornea; Cross-Over Studies; Disinfectants; Double-Blind Method; Equipment Design; Female; Fluorescein; Fluorescent Dyes; Follow-Up Studies; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Male; New South Wales; Preservatives, Pharmaceutical; Prospective Studies; Silicones; Staining and Labeling; Time Factors; Young Adult | 2010 |
Clinical trial of 0.02% polyhexamethylene biguanide versus placebo in the treatment of microsporidial keratoconjunctivitis.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Biguanides; Child; Disinfectants; Double-Blind Method; Eye Infections, Fungal; Female; Humans; Keratoconjunctivitis; Male; Microsporida; Microsporidiosis; Middle Aged; Ophthalmic Solutions; Prospective Studies; Time Factors; Treatment Outcome; Visual Acuity | 2010 |
Prospective randomized trial of accelerated re-epithelization of skin graft donor sites using extracorporeal shock wave therapy.
Topics: Adult; Aged; Anti-Infective Agents, Local; Biguanides; Burns; Epithelium; Female; Humans; Imines; Lithotripsy; Male; Middle Aged; Neovascularization, Physiologic; Occlusive Dressings; Prospective Studies; Pyridines; Regeneration; Silicones; Single-Blind Method; Skin Transplantation; Surgical Mesh; Time Factors; Transplantation, Autologous; Treatment Outcome; Wound Healing | 2010 |
Evaluation of the efficacy and tolerability of a solution containing propyl betaine and polihexanide for wound irrigation.
Topics: Aged; Anti-Infective Agents, Local; Betaine; Biguanides; Biofilms; Female; Humans; Hydrogen-Ion Concentration; Male; Middle Aged; Pain Measurement; Pressure Ulcer; Skin Care; Therapeutic Irrigation; Time Factors; Treatment Outcome; Varicose Ulcer; Wound Healing | 2010 |
Impact of a rub and rinse on solution-induced corneal staining.
Topics: Adolescent; Adult; Biguanides; Contact Lens Solutions; Contact Lenses, Hydrophilic; Cornea; Disinfectants; Double-Blind Method; Humans; Hydrogels; Massage; Middle Aged; Primary Prevention; Silicones; Staining and Labeling; Therapeutic Irrigation; Young Adult | 2010 |
Efficacy of intraoperative surgical irrigation with polihexanide and nitrofurazone in reducing bacterial load after nail removal surgery.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Colony Count, Microbial; Female; Humans; Intraoperative Care; Male; Middle Aged; Nails, Ingrown; Nitrofurazone; Plastic Surgery Procedures; Surgical Wound Infection; Therapeutic Irrigation | 2011 |
Reduction of bacterial burden and pain in chronic wounds using a new polyhexamethylene biguanide antimicrobial foam dressing-clinical trial results.
Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bandages; Biguanides; Canada; Chronic Disease; Colony Count, Microbial; Female; Humans; Leg Ulcer; Male; Middle Aged; Pain; Pilot Projects; Pressure Ulcer; Treatment Outcome; Wound Healing | 2011 |
Randomized controlled single center study comparing a polyhexanide containing bio-cellulose dressing with silver sulfadiazine cream in partial-thickness dermal burns.
Topics: Adult; Anti-Infective Agents, Local; Bandages; Biguanides; Biocompatible Materials; Burns; Cellulose; Female; Health Care Costs; Humans; Male; Middle Aged; Pain Measurement; Prospective Studies; Silver Sulfadiazine; Wound Healing; Young Adult | 2011 |
A preliminary study of silicone hydrogel lens material and care solution bioincompatibilities.
Topics: Adult; Biguanides; Contact Lens Solutions; Contact Lenses, Hydrophilic; Cross-Over Studies; Double-Blind Method; Epithelium, Corneal; Female; Fluorescein; Fluorophotometry; Humans; Hydrogels; Male; Materials Testing; Permeability; Polymers; Propylamines; Refractive Errors; Silicones; Staining and Labeling; Young Adult | 2011 |
First experiences with negative pressure wound therapy and instillation in the treatment of infected orthopaedic implants: a clinical observational study.
Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; Chronic Disease; Combined Modality Therapy; Debridement; Female; Humans; Male; Middle Aged; Negative-Pressure Wound Therapy; Prospective Studies; Prosthesis-Related Infections; Therapeutic Irrigation; Treatment Outcome | 2011 |
Prospective randomized phase II Trial of accelerated reepithelialization of superficial second-degree burn wounds using extracorporeal shock wave therapy.
Topics: Adult; Aged; Anti-Infective Agents, Local; Biguanides; Burns; Cohort Studies; Debridement; Female; Germany; Humans; Imines; Male; Middle Aged; Pyridines; Ultrasonic Therapy; Wound Healing | 2012 |
Antimicrobial gauze as a dressing reduces pin site infection: a randomized controlled trial.
Topics: Adolescent; Adult; Aged; Bandages; Biguanides; Bone Nails; Chi-Square Distribution; Child; Child, Preschool; Disinfectants; Double-Blind Method; Female; Fracture Fixation; Humans; Malaysia; Male; Metals; Middle Aged; Prosthesis Design; Prosthesis-Related Infections; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome; Young Adult | 2012 |
Eradication of methicillin-resistant Staphylococcus aureus in pressure ulcers comparing a polyhexanide-containing cellulose dressing with polyhexanide swabs in a prospective randomized study.
Topics: Adult; Aged; Bandages; Biguanides; Cellulose; Disease Progression; Female; Health Status Indicators; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Pain Measurement; Pressure Ulcer; Staphylococcal Infections | 2012 |
A cohort study on the efficacy of a polyhexanide-containing biocellulose dressing in the treatment of biofilms in wounds.
Topics: Biguanides; Biofilms; Cellulose; Chronic Disease; Disinfectants; Female; Humans; Male; Middle Aged; Netherlands; Occlusive Dressings; Prospective Studies; Wound Healing; Wound Infection | 2011 |
Comparison of PHMB-containing dressing and silver dressings in patients with critically colonised or locally infected wounds.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Bacterial Infections; Bacterial Load; Bandages; Biguanides; Cellulose; Female; Humans; Male; Middle Aged; Pain; Quality of Life; Silver; Single-Blind Method; Wound Infection | 2012 |
Efficacy of intraoperative antiseptic scrub after nail removal surgery.
Topics: Anti-Infective Agents, Local; Biguanides; Humans; Intraoperative Care; Nails; Prospective Studies; Surgical Wound Infection | 2013 |
Evaluation of the antiseptic efficacy and local tolerability of a polihexanide-based antiseptic on resident skin flora.
Topics: Adult; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Colony Count, Microbial; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Skin; Skin Diseases, Bacterial | 2012 |
Prospective cohort study on surgical wounds comparing a polyhexanide-containing biocellulose dressing with a dialkyl-carbamoyl-chloride-containing hydrophobic dressing.
Topics: Aged; Anti-Infective Agents; Bandages; Biguanides; Biocompatible Materials; Cohort Studies; Diabetic Foot; Female; Humans; Hydrophobic and Hydrophilic Interactions; Male; Middle Aged; Pain; Pain Measurement; Prospective Studies; Surgical Wound Infection; Wound Healing | 2012 |
In vivo investigation of the efficiency of a nanoparticle-emulsion containing polihexanide on the human skin.
Topics: Adult; Anti-Infective Agents, Local; Biguanides; Colony Count, Microbial; Disinfection; Double-Blind Method; Drug Carriers; Drug Combinations; Emulsions; Hair Follicle; Humans; Male; Middle Aged; Nanoparticles; Phospholipids; Skin; Sorbitol; Time Factors; Wound Infection; Young Adult | 2013 |
Antisepsis regimen in the surgical treatment of HPV generated cervical lesions: polyhexamethylene biguanide vs chlorhexidine. A randomized, double blind study.
Topics: Administration, Intravaginal; Adult; Anti-Infective Agents, Local; Antisepsis; Biguanides; Chlorhexidine; Colposcopy; Double-Blind Method; Drug Administration Schedule; Female; Humans; Italy; Laser Therapy; Lasers, Gas; Papillomavirus Infections; Prospective Studies; Suppositories; Surgical Wound Infection; Time Factors; Treatment Outcome; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms; Vaginal Smears; Young Adult | 2012 |
Increased peritoneal dialysis exit site infections using topical antiseptic polyhexamethylene biguanide compared to mupirocin: results of a safety interim analysis of an open-label prospective randomized study.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Catheters, Indwelling; Early Termination of Clinical Trials; Female; Humans; Male; Middle Aged; Mupirocin; Peritoneal Dialysis; Prospective Studies; Pseudomonas Infections; Staphylococcal Infections; Survival Analysis | 2013 |
Exit-site infection of peritoneal catheter is reduced by the use of polyhexanide. results of a prospective randomized trial.
Topics: Biguanides; Catheter-Related Infections; Catheters, Indwelling; Female; Follow-Up Studies; Humans; Male; Middle Aged; Peritoneal Dialysis; Prospective Studies; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome | 2014 |
Randomized, placebo-controlled, double-blind clinical trial to evaluate the efficacy of polyhexanide for topical decolonization of MRSA carriers.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; Carrier State; Double-Blind Method; Drug Resistance, Bacterial; Drug-Related Side Effects and Adverse Reactions; Female; Hospitals, Teaching; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Placebos; Staphylococcal Infections; Treatment Outcome; Young Adult | 2016 |
Reducing the pathogen burden and promoting healing with polyhexanide in non-healing wounds: a prospective study.
Topics: Aged; Anti-Infective Agents, Local; Bacterial Infections; Biguanides; C-Reactive Protein; Cohort Studies; Female; Humans; Lymphocyte Count; Male; Middle Aged; Prospective Studies; Surgical Wound Infection; Thoracic Surgical Procedures; Wound Healing | 2015 |
Determinants of Successful Methicillin-Resistant Staphylococcus aureus Decolonization.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; Carrier State; Drug Resistance, Bacterial; Female; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Staphylococcal Infections; Treatment Outcome | 2016 |
Effect of a wound cleansing solution on wound bed preparation and inflammation in chronic wounds: a single-blind RCT.
Topics: Aged; Aged, 80 and over; Bandages; Betaine; Biguanides; Chronic Disease; Female; Humans; Inflammation; Male; Middle Aged; Pressure Ulcer; Single-Blind Method; Sodium Chloride; Solutions; Therapeutic Irrigation; Varicose Ulcer; Wounds and Injuries | 2016 |
Pilot Study to Determine the Effect of Lens and Eye Rinsing on Solution-Induced Corneal Staining (SICS).
Topics: Adolescent; Adult; Biguanides; Contact Lens Solutions; Contact Lenses, Hydrophilic; Cornea; Disinfectants; Double-Blind Method; Epithelial Cells; Female; Humans; Hydrogels; Middle Aged; Pilot Projects; Prospective Studies; Silicones; Staining and Labeling; Therapeutic Irrigation | 2016 |
Can dressings soaked with polyhexanide reduce bacterial loads in full-thickness skin grafting? A randomized controlled trial.
Topics: Aged; Aged, 80 and over; Autografts; Bacterial Load; Bandages; Biguanides; Disinfectants; Double-Blind Method; Female; Humans; Male; Middle Aged; Nose; Prospective Studies; Skin; Skin Transplantation; Staphylococcus aureus; Surgical Wound Infection | 2016 |
The Effect of Polyhexanide, Octenidine Dihydrochloride, and Tea Tree Oil as Topical Antiseptic Agents on In Vivo Microcirculation of the Human Skin: A Noninvasive Quantitative Analysis.
Topics: Administration, Topical; Adult; Anti-Infective Agents, Local; Biguanides; Blood Flow Velocity; Evaluation Studies as Topic; Female; Healthy Volunteers; Humans; Imines; Male; Microcirculation; Microscopy, Fluorescence; Pyridines; Skin; Tea Tree Oil; Wound Healing; Young Adult | 2016 |
Chlorhexidine gluconate or polyhexamethylene biguanide disc dressing to reduce the incidence of central-line-associated bloodstream infection: a feasibility randomized controlled trial (the CLABSI trial).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bandages; Biguanides; Catheter-Related Infections; Catheterization, Central Venous; Chlorhexidine; Disinfectants; Disinfection; Female; Humans; Incidence; Male; Middle Aged; Sepsis; Tertiary Care Centers; Treatment Outcome; Young Adult | 2017 |
Randomized Controlled Trial of Polyhexanide/Betaine Gel Versus Silver Sulfadiazine for Partial-Thickness Burn Treatment.
Topics: Adult; Anti-Infective Agents, Local; Bandages, Hydrocolloid; Betaine; Biguanides; Burns; Drug Combinations; Drug Monitoring; Female; Humans; Male; Middle Aged; Patient Care Management; Silver Sulfadiazine; Trauma Severity Indices; Treatment Outcome; Wound Healing | 2017 |
Intraoperative wound irrigation to prevent surgical site infection after laparotomy (IOWISI): study protocol for a randomized controlled trial.
Topics: Anti-Infective Agents, Local; Biguanides; Clinical Protocols; Double-Blind Method; Germany; Humans; Intention to Treat Analysis; Intraoperative Care; Laparotomy; Research Design; Risk Factors; Surgical Wound Infection; Therapeutic Irrigation; Time Factors; Treatment Outcome | 2017 |
Randomized controlled clinical trial on the antiseptic efficacy of polihexanide 0.04% on acute traumatic wounds.
Topics: Adult; Aged; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Colony Count, Microbial; Double-Blind Method; Humans; Male; Middle Aged; Placebos; Prospective Studies; Treatment Outcome; Wound Infection; Wounds and Injuries; Young Adult | 2018 |
Efficacy of a Gel Containing Polihexanide and Betaine in Deep Partial and Full Thickness Burns Requiring Split-thickness Skin Grafts: A Noncomparative Clinical Study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Betaine; Biguanides; Burns; Disinfectants; Female; Gels; Humans; Lipotropic Agents; Male; Middle Aged; Prospective Studies; Skin Transplantation; Wound Healing; Young Adult | 2018 |
Inflammatory reaction, clinical efficacy, and safety of bacterial cellulose wound dressing containing silk sericin and polyhexamethylene biguanide for wound treatment.
Topics: Bandages; Biguanides; Cellulose; Disinfectants; Erythema; Female; Humans; Inflammation; Interleukin-4; Male; Middle Aged; Polysaccharides, Bacterial; Sericins; Skin Transplantation; Transforming Growth Factor beta1; Treatment Outcome; Wound Healing | 2018 |
Comparison of polyhexanide, cold atmospheric plasma and saline in the treatment of canine bite wounds.
Topics: Animals; Biguanides; Dogs; Plasma Gases; Prospective Studies; Wound Healing | 2019 |
Effect of Local Polyhexanide Application in Preventing Exit-Site Infection and Peritonitis: A Randomized Controlled Trial.
Topics: Adult; Anti-Infective Agents, Local; Biguanides; Catheter-Related Infections; Device Removal; Female; Follow-Up Studies; Humans; Male; Middle Aged; Peritoneal Dialysis; Peritonitis; Povidone-Iodine; Prospective Studies | 2020 |
Reduction of Postoperative Wound Infections by Antiseptica (RECIPE)?: A Randomized Controlled Trial.
Topics: Biguanides; Digestive System Surgical Procedures; Disinfectants; Female; Humans; Intraoperative Care; Laparotomy; Length of Stay; Male; Middle Aged; Pain, Postoperative; Patient Satisfaction; Prospective Studies; Single-Blind Method; Sodium Chloride; Surgical Wound Infection; Therapeutic Irrigation | 2020 |
Does negative pressure wound therapy with irrigation improve clinical outcomes? A randomized clinical trial in patients with diabetic foot infections.
Topics: Administration, Topical; Adult; Biguanides; Diabetic Foot; Disinfectants; Female; Humans; Male; Middle Aged; Negative-Pressure Wound Therapy; Therapeutic Irrigation; Treatment Outcome; Wound Healing | 2020 |
A randomized masked pilot clinical trial to compare the efficacy of topical 1% voriconazole ophthalmic solution as monotherapy with combination therapy of topical 0.02% polyhexamethylene biguanide and 0.02% chlorhexidine in the treatment of Acanthamoeba k
Topics: Acanthamoeba Keratitis; Biguanides; Chlorhexidine; Humans; Ophthalmic Solutions; Prospective Studies; Voriconazole | 2021 |
Safety and tolerability of topical polyhexamethylene biguanide: a randomised clinical trial in healthy adult volunteers.
Topics: Acanthamoeba Keratitis; Adult; Biguanides; Healthy Volunteers; Humans; Prospective Studies | 2022 |
Use of low-frequency contact ultrasonic debridement with and without polyhexamethylene biguanide in hard-to-heal leg ulcers: an RCT protocol.
Topics: Biguanides; Debridement; Disinfectants; Humans; Leg Ulcer; Randomized Controlled Trials as Topic; Ultrasonics; Wound Healing | 2021 |
Polyhexamethylene biguanide discs versus unmedicated dressings for prevention of central venous catheter-associated infection in the intensive care unit: A pilot randomised controlled trial to assess protocol safety and feasibility.
Topics: Adult; Bandages; Biguanides; Catheter-Related Infections; Catheterization, Central Venous; Chlorhexidine; Feasibility Studies; Humans; Intensive Care Units; Pilot Projects; Randomized Controlled Trials as Topic; Sepsis | 2022 |
Microbiological identification and resistance profile of microorganisms in pressure injuries after the use of polyhexamethylene biguanide: a series of fourteen cases.
Topics: Anti-Bacterial Agents; Biguanides; Humans; Methicillin-Resistant Staphylococcus aureus; Pressure Ulcer; Pseudomonas aeruginosa | 2022 |
Use of low-frequency contact ultrasonic debridement with and without polyhexamethylene biguanide in hard-to-heal leg ulcers: an RCT.
Topics: Adult; Biguanides; Debridement; Humans; Leg Ulcer; Pain; Quality of Life; Ultrasonics; Wound Healing | 2022 |
400 other study(ies) available for vantocil and biguanides
| Article | Year |
|---|---|
[Photometric detection of metacide in the air of the working area].
Topics: Air Pollutants, Occupational; Biguanides; Disinfectants; Photometry | 1992 |
A quantitative method for LDH, MDH and albumin levels in tears with ocular surface toxicity scored by Draize criteria in rabbit eyes.
Topics: Albumins; Animals; Benzalkonium Compounds; Biguanides; Chlorhexidine; Eye; L-Lactate Dehydrogenase; Malate Dehydrogenase; Preservatives, Pharmaceutical; Rabbits; Tears | 1992 |
Relationship between Legionella pneumophila and Acanthamoeba polyphaga: physiological status and susceptibility to chemical inactivation.
Topics: Acanthamoeba; Animals; Biguanides; Disinfectants; Drug Resistance; Iron; Legionella pneumophila; Thiazoles; Water Microbiology | 1992 |
Treatment of Acanthamoeba keratitis with polyhexamethylene biguanide.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Aged; Animals; Anti-Bacterial Agents; Biguanides; Drug Resistance; Female; Humans; Male; Middle Aged; Treatment Outcome; Visual Acuity | 1992 |
Prevention of contamination in waterbaths.
Topics: Baths; Biguanides; Disinfectants; Pseudomonas fluorescens; Water Microbiology | 1990 |
Barrier properties of the gram-negative cell envelope towards high molecular weight polyhexamethylene biguanides.
Topics: Biguanides; Cell Membrane; Cell Membrane Permeability; Disinfectants; Escherichia coli; Lipopolysaccharides; Polymers; Potassium | 1990 |
Synergism within polyhexamethylene biguanide biocide formulations.
Topics: Adsorption; Biguanides; Binding Sites; Biological Transport; Centrifugation; Disinfectants; Drug Synergism; Escherichia coli; Magnesium; Molecular Weight; Osmotic Pressure; Polymers | 1990 |
Interaction of the bisbiguanides chlorhexidine and alexidine with phospholipid vesicles: evidence for separate modes of action.
Topics: Anti-Bacterial Agents; Biguanides; Cell Membrane Permeability; Chlorhexidine; Drug Resistance, Microbial; Escherichia coli; Phospholipids; Proteus; Providencia; Spheroplasts | 1989 |
A study of the antibacterial activity of some polyhexamethylene biguanides towards Escherichia coli ATCC 8739.
Topics: Bacteriolysis; Biguanides; Cell Membrane; Cell Membrane Permeability; Dose-Response Relationship, Drug; Escherichia coli; Polymers; Spheroplasts | 1983 |
Injury and recovery of Escherichia coli ATCC 8739 from treatment with some polyhexamethylene biguanides.
Topics: Antimycin A; Biguanides; Cell Membrane; Cell Membrane Permeability; Escherichia coli; Fluorescent Dyes; Hydroxysteroid Dehydrogenases; Naphthalenesulfonates | 1984 |
Interaction of some polyhexamethylene biguanides and membrane phospholipids in Escherichia coli.
Topics: Biguanides; Cell Membrane; Disinfectants; Escherichia coli; Magnetic Resonance Spectroscopy; Membrane Lipids; Phospholipids | 1984 |
Binding of some polyhexamethylene biguanides to the cell envelope of Escherichia coli ATCC 8739.
Topics: Biguanides; Cell Wall; Disinfectants; Electrophoresis; Escherichia coli; Hydrogen-Ion Concentration; Lipopolysaccharides | 1984 |
Interaction of biologically active molecules with phospholipid membranes. I. Fluorescence depolarization studies on the effect of polymeric biocide bearing biguanide groups in the main chain.
Topics: Biguanides; Diphenylhexatriene; Disinfectants; Fluorescence Polarization; Liposomes; Membrane Lipids; Phosphatidylcholines; Phosphatidylglycerols; Phospholipids; Polymyxin B | 1983 |
Interaction of a polymeric biguanide biocide with phospholipid membranes.
Topics: Biguanides; Calorimetry; Fluorescence Polarization; Lipid Bilayers; Liposomes; Phospholipids; Polymers; Temperature | 1984 |
Survey of bacteria in private swimming pools.
Topics: Biguanides; Chlorine; Disinfectants; Escherichia coli; Pseudomonas aeruginosa; Staphylococcus aureus; Swimming Pools; Water Microbiology | 1981 |
High-alkaline protease from Bacillus PB92 entrapped in calcium alginate gel. Physicochemical and microscopic studies.
Topics: Alginates; Amino Acid Sequence; Bacillus; Biguanides; Capsules; Caseins; Detergents; Disinfectants; Enzyme Stability; Enzymes, Immobilized; Gels; Glucuronic Acid; Hexuronic Acids; Hydrogen-Ion Concentration; Microspheres; Molecular Sequence Data; Serine Endopeptidases; Sodium Dodecyl Sulfate; Substrate Specificity; Subtilisins; Temperature; Viscosity | 1995 |
Cytogenetic toxicity and no-effect limit dose of pesticides.
Topics: Allium; Animals; Biguanides; Bone Marrow; Bone Marrow Cells; Chromosomes; Disinfectants; Dose-Response Relationship, Drug; Drosophila melanogaster; Hexachlorocyclohexane; Malathion; Mice; Mitosis; Mitotic Index; Mutation; Pest Control; Pesticides; Plant Roots; X Chromosome | 1995 |
Corneal infection associated with Hartmannella vermiformis in contact-lens wearer.
Topics: Adolescent; Amebiasis; Animals; Biguanides; Contact Lenses, Hydrophilic; Corneal Diseases; Diagnosis, Differential; Female; Hartmannella; Humans | 1995 |
Diagnosis of Acanthamoeba keratitis in vivo with confocal microscopy.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Adult; Aged; Amebicides; Animals; Benzamidines; Biguanides; Cornea; Female; Humans; Male; Microscopy, Confocal; Middle Aged | 1995 |
Drug therapy in a murine model of Acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Animals; Antiprotozoal Agents; Benzamidines; Biguanides; Disease Models, Animal; Feasibility Studies; Male; Rats | 1995 |
A comparative study of the microbiologic effectiveness of chemical disinfectants and peroxide-neutralizer systems.
Topics: Biguanides; Colony Count, Microbial; Contact Lens Solutions; Contact Lenses; Disinfection; Equipment Contamination; Evaluation Studies as Topic; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Hydrogen Peroxide; Patient Compliance; Polymers | 1995 |
Chlorhexidine or polyhexamethylene biguanide for acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Biguanides; Chlorhexidine; Disinfectants; Humans; Ophthalmic Solutions | 1995 |
Chemotherapy for acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Administration, Topical; Amebicides; Benzamidines; Biguanides; Chlorhexidine; Disinfectants; Drug Approval; Humans | 1995 |
Chemotherapy for acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Antiprotozoal Agents; Benzamidines; Biguanides; Chlorhexidine; Disinfectants; Drug Therapy, Combination; Humans | 1995 |
Acanthamoeba keratitis: a sobering case and a promising new treatment.
Topics: Acanthamoeba Keratitis; Adult; Animals; Anti-Bacterial Agents; Biguanides; Cataract; Contact Lenses, Hydrophilic; Drug Therapy, Combination; Equipment Contamination; Humans; Male | 1994 |
A review of 72 consecutive cases of Acanthamoeba keratitis, 1984-1992.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Animals; Antiprotozoal Agents; Benzamidines; Biguanides; Contact Lenses, Hydrophilic; Drug Therapy, Combination; Equipment Contamination; Humans; Keratoplasty, Penetrating; Prognosis; Prospective Studies; Retrospective Studies; Treatment Outcome | 1993 |
Topical polyhexamethylene biguanide (pool cleaner) for treatment of acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Biguanides; Disinfectants; Humans; Ophthalmic Solutions | 1993 |
Polyhexamethylene biguanide in the treatment of Acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Adolescent; Antiprotozoal Agents; Biguanides; Contact Lenses, Hydrophilic; Disposable Equipment; Humans; Male; Recurrence | 1993 |
Combined treatment of Acanthamoeba keratitis with propamidine, neomycin, and polyhexamethylene biguanide.
Topics: Acanthamoeba Keratitis; Adolescent; Adult; Animals; Benzamidines; Biguanides; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Male; Neomycin; Ophthalmic Solutions; Visual Acuity | 1993 |
Confocal microscopy findings of Acanthamoeba keratitis.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Animals; Anti-Bacterial Agents; Biguanides; Contact Lenses, Extended-Wear; Contact Lenses, Hydrophilic; Corneal Stroma; Drug Therapy, Combination; Epithelium; Female; Humans; Microscopy, Confocal; Middle Aged; Ophthalmic Solutions | 1996 |
Effect of biocide concentration on electrorotation spectra of yeast cells.
Topics: Biguanides; Electricity; Electrodes; Electrophysiology; Mathematics; Saccharomyces cerevisiae | 1996 |
Effects of polyhexamethylene biguanide and chlorhexidine on four species of Acanthamoeba in vitro.
Topics: Acanthamoeba; Amebicides; Animals; Biguanides; Chlorhexidine; Disinfectants; Dose-Response Relationship, Drug; Drug Synergism; Osmolar Concentration; Time Factors | 1996 |
[Acanthamoeba keratitis].
Topics: Acanthamoeba Keratitis; Adult; Aged; Amebicides; Anti-Bacterial Agents; Benzamidines; Biguanides; Contact Lenses, Hydrophilic; Diagnosis, Differential; Disinfectants; Drug Therapy, Combination; Female; Humans; Keratitis, Dendritic; Neomycin | 1996 |
Acanthamoeba keratitis: risk factors and outcome.
Topics: Acanthamoeba Keratitis; Antiprotozoal Agents; Benzamidines; Biguanides; Humans | 1996 |
The effects of adding chlorhexidine and polyhexamethylene bisguanide to a light-cured periodontal dressing material.
Topics: Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Dental Disinfectants; Elasticity; Materials Testing; Periodontal Dressings; Resins, Synthetic; Tensile Strength; Water; Wettability | 1996 |
Aspects of the mechanisms of action of biguanides on trophozoites and cysts of Acanthamoeba castellanii.
Topics: Acanthamoeba; Animals; Biguanides; Cell Membrane; Chlorhexidine; Disinfectants; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Pentoses | 1997 |
Polyhexamethylene biguanide (PHMB) in the treatment of experimental Fusarium keratomycosis.
Topics: Administration, Topical; Animals; Biguanides; Colony Count, Microbial; Cornea; Disease Models, Animal; Disinfectants; Eye Infections, Fungal; Fusarium; Keratitis; Ophthalmic Solutions; Rabbits; Treatment Outcome | 1997 |
Treatment of Nocardia asteroides keratitis with polyhexamethylene biguanide.
Topics: Adolescent; Biguanides; Dose-Response Relationship, Drug; Humans; Keratitis; Male; Microbial Sensitivity Tests; Nocardia asteroides; Nocardia Infections; Osmolar Concentration | 1997 |
Should we be using polyhexamethylene biguanide to treat Acanthamoeba keratitis?
Topics: Acanthamoeba Keratitis; Administration, Topical; Biguanides; Contact Lenses; Cornea; Disinfectants; Female; Humans; Ophthalmic Solutions | 1997 |
In vitro and in vivo effects of polyhexamethylene biguanide against herpes simplex virus infection.
Topics: Administration, Topical; Animals; Antibodies, Viral; Biguanides; Cattle; Cornea; Disease Models, Animal; Disinfectants; Dose-Response Relationship, Drug; Follow-Up Studies; Herpesvirus 1, Human; Keratitis, Herpetic; Ophthalmic Solutions; Rabbits; Treatment Outcome | 1997 |
Effects of biocides on Acanthamoeba castellanii as measured by flow cytometry and plaque assay.
Topics: Acanthamoeba; Animals; Anti-Infective Agents, Local; Biguanides; Cell Count; Chlorhexidine; Dose-Response Relationship, Drug; Flow Cytometry; Membranes | 1997 |
Outcome of acanthamoeba keratitis treated with polyhexamethyl biguanide and propamidine.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Adult; Animals; Antiprotozoal Agents; Benzamidines; Biguanides; Contact Lenses; Cornea; Disinfectants; Drug Therapy, Combination; Female; Humans; Keratoplasty, Penetrating; Male; Middle Aged; Retrospective Studies; Treatment Outcome; Visual Acuity | 1997 |
Antiseptic efficacy of disinfecting solutions in suspension test in vitro against methicillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli in pressure sore wounds after spinal cord injury.
Topics: Anti-Infective Agents, Local; Biguanides; Chamomile; Chlorhexidine; Escherichia coli; Escherichia coli Infections; Flavonoids; Humans; Imines; Iodophors; Methicillin Resistance; Oils, Volatile; Plants, Medicinal; Povidone-Iodine; Pressure Ulcer; Pseudomonas aeruginosa; Pseudomonas Infections; Pyridines; Quaternary Ammonium Compounds; Serum Albumin; Skin; Spinal Cord Injuries; Staphylococcal Infections; Staphylococcus aureus | 1997 |
Acanthamoeba castellanii: growth, encystment, excystment and biocide susceptibility.
Topics: Acanthamoeba; Animals; Biguanides; Chlorhexidine; Disinfectants; Life Cycle Stages | 1998 |
Polyhexamethylene biguanide treatment for Acanthamoeba keratitis.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Animals; Anti-Bacterial Agents; Biguanides; Disinfectants; Drug Therapy, Combination; Follow-Up Studies; Humans; Ophthalmic Solutions; Treatment Outcome | 1998 |
Ultrastructural changes of Acanthamoeba cyst of clinical isolates after treatment with minimal cysticidal concentration of polyhexamethylene biguanide.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Animals; Biguanides; Disinfectants; Drug Resistance; Humans; Microscopy, Electron | 1998 |
Is polyhexamethylene biguanide alone effective for Acanthamoeba keratitis?
Topics: Acanthamoeba; Acanthamoeba Keratitis; Administration, Topical; Adult; Animals; Biguanides; Cornea; Disinfectants; Female; Follow-Up Studies; Humans; Ophthalmic Solutions; Visual Acuity | 1998 |
Changes in the biocide susceptibility of Staphylococcus epidermidis and Escherichia coli cells associated with rapid attachment to plastic surfaces.
Topics: Anti-Infective Agents, Local; Bacterial Adhesion; Biguanides; Biofilms; Cetrimonium; Cetrimonium Compounds; Disinfectants; Escherichia coli; Microbial Sensitivity Tests; Peracetic Acid; Staphylococcus epidermidis; Xylenes | 1998 |
Acanthamoeba keratitis in New Zealand, including two cases with in vivo resistance to polyhexamethylene biguanide.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Animals; Biguanides; Contact Lens Solutions; Contact Lenses, Hydrophilic; Cornea; Drug Resistance; Female; Humans; Male; Middle Aged; New Zealand; Treatment Outcome | 1998 |
Severe anaphylaxis to a new disinfectant: polyhexanide, a chlorhexidine polymer.
Topics: Administration, Topical; Adolescent; Anaphylaxis; Biguanides; Chlorhexidine; Disinfectants; Female; Humans; Male; Polymers | 1998 |
X-ray microanalysis of chlorine and phosphorus content in biguanide-treated Acanthamoeba castellanii.
Topics: Acanthamoeba; Animals; Biguanides; Chlorine; Disinfectants; Electron Probe Microanalysis; Phosphorus; Vacuoles | 1999 |
Effect of topical 0.02% polyhexamethylene biguanide on nocardial keratitis associated with scleritis.
Topics: Administration, Topical; Adult; Biguanides; Disinfectants; Eye Infections, Bacterial; Follow-Up Studies; Humans; Keratitis; Male; Nocardia; Nocardia Infections; Scleritis | 1998 |
In-vitro activity of polyhexamethylene biguanide (PHMB) against fungal isolates associated with infective keratitis.
Topics: Biguanides; Disinfectants; Eye Infections, Fungal; Humans; Keratitis; Microbial Sensitivity Tests; Mitosporic Fungi | 1999 |
Treatment of Acanthamoeba keratitis combined with fungal infection with polyhexamethylene biguanide.
Topics: Acanthamoeba Keratitis; Adult; Biguanides; Disinfectants; Eye Infections, Fungal; Fungi; Humans; Male; Microbial Sensitivity Tests; Middle Aged | 1999 |
In vitro action of a combination of selected antimicrobial agents and chondroitin sulfate.
Topics: Anti-Infective Agents, Local; Biguanides; Candida albicans; Cetylpyridinium; Chlorhexidine; Chondroitin Sulfates; Drug Interactions; Enterococcus faecium; Escherichia coli; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus | 2000 |
Flow cytometry for determination of the efficacy of contact lens disinfecting solutions against Acanthamoeba spp.
Topics: Acanthamoeba; Animals; Biguanides; Chlorhexidine; Contact Lens Solutions; Flow Cytometry; Methylene Blue; Staining and Labeling | 2000 |
Polyhexamethylenebiguanide: a relevant contact allergen?
Topics: Adult; Biguanides; Dermatitis, Contact; Disinfectants; Female; Humans; Male; Molecular Structure; Patch Tests | 2000 |
The reculture technique: individualizing the treatment of Acanthamoeba keratitis.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Adult; Animals; Antiprotozoal Agents; Benzamidines; Biguanides; Child; Child, Preschool; Chlorhexidine; Cornea; Culture Media; Disinfectants; Female; Humans; Male; Ophthalmic Solutions; Parasitic Sensitivity Tests | 2000 |
Therapy of acanthamoeba keratitis--an experimental study.
Topics: Acanthamoeba Keratitis; Animals; Biguanides; Female; Fluconazole; Male; Neomycin; Povidone-Iodine; Rabbits | 2000 |
Polyhexamethylene biguanide (0.02%) alone is not adequate for treating chronic Acanthameoba keratitis.
Topics: Acanthamoeba Keratitis; Biguanides; Chronic Disease; Disinfectants; Humans; Treatment Failure | 2000 |
Coexistent adenoviral keratoconjunctivitis and Acanthamoeba keratitis.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Acyclovir; Adenovirus Infections, Human; Adenoviruses, Human; Adolescent; Animals; Biguanides; Cyclopentolate; Drug Therapy, Combination; Eye Infections, Viral; Humans; Keratoconjunctivitis; Male; Prednisolone | 2000 |
Viability of Acanthamoeba after exposure to a multipurpose disinfecting contact lens solution and two hydrogen peroxide systems.
Topics: Acanthamoeba; Animals; Biguanides; Contact Lens Solutions; Disinfectants; Disinfection; Equipment Contamination; Humans; Hydrogen Peroxide | 2002 |
Development and application of an in vitro susceptibility test for Acanthamoeba species isolated from keratitis to polyhexamethylene biguanide and chlorhexidine.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Animals; Biguanides; Chlorhexidine; Disinfectants; Dose-Response Relationship, Drug; Humans; Osmolar Concentration; Parasitic Sensitivity Tests; Time Factors | 2002 |
Phagocytosis affects biguanide sensitivity of Acanthamoeba spp.
Topics: Acanthamoeba; Animals; Biguanides; Chlorhexidine; Contact Lens Solutions; Disinfectants; Dose-Response Relationship, Drug; Flow Cytometry; Parasitic Sensitivity Tests; Phagocytosis | 2002 |
[Acanthamoeba keratitis treated with propamidine and polyhexamethyl biguanide (PHMB)].
Topics: Acanthamoeba Keratitis; Amebicides; Benzamidines; Biguanides; Contact Lenses; Disinfectants; Drug Therapy, Combination; Humans; Prognosis; Retrospective Studies; Visual Acuity | 2002 |
Treatment of advanced acanthamoeba keratitis with deep lamellar keratectomy and conjunctival flap.
Topics: Acanthamoeba Keratitis; Adult; Antiprotozoal Agents; Biguanides; Conjunctiva; Contact Lenses; Cornea; Female; Humans; Ophthalmologic Surgical Procedures; Palliative Care; Surgical Flaps; Visual Acuity | 2002 |
Influence of antiseptic agents on interleukin-8 release and transmigration of polymorphonuclear neutrophils in a human in vitro model of peritonitis.
Topics: Anti-Infective Agents, Local; Anti-Inflammatory Agents; Biguanides; Cell Movement; Dose-Response Relationship, Drug; Endothelial Cells; Endothelium, Vascular; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Interleukin-8; Neutrophils; P-Selectin; Peritoneal Cavity; Peritonitis; Taurine; Thiadiazines; Time Factors; Tumor Necrosis Factor-alpha | 2002 |
Role of 0.02% polyhexamethylene biguanide and 1% povidone iodine in experimental Aspergillus keratitis.
Topics: Animals; Anti-Infective Agents, Local; Aspergillosis; Aspergillus fumigatus; Biguanides; Corneal Stroma; Disinfectants; Drug Evaluation; Eye Infections, Fungal; Keratitis; Natamycin; Ophthalmic Solutions; Povidone-Iodine; Prospective Studies; Rabbits; Random Allocation | 2003 |
Performance of contact lens disinfecting solutions against Pseudomonas aeruginosa in the presence of organic load.
Topics: Biguanides; Colony Count, Microbial; Contact Lens Solutions; Disinfection; Microbial Sensitivity Tests; Preservatives, Pharmaceutical; Pseudomonas aeruginosa; Soil Microbiology | 2003 |
Potassium and tetraphenylphosphonium ion-selective electrodes for monitoring changes in the permeability of bacterial outer and cytoplasmic membranes.
Topics: Biguanides; Cell Membrane; Cell Membrane Permeability; Chlorhexidine; Disinfectants; Gram-Negative Bacteria; Intracellular Membranes; Ion-Selective Electrodes; Lipopolysaccharides; Onium Compounds; Organophosphorus Compounds; Potassium | 2003 |
Bilateral Acanthamoeba keratitis with late recurrence of the infection in a corneal graft: a case report.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Animals; Anti-Bacterial Agents; Benzamidines; Biguanides; Contact Lenses, Hydrophilic; Cornea; Disinfectants; Humans; Keratoplasty, Penetrating; Male; Neomycin; Recurrence; Time Factors; Treatment Outcome; Visual Acuity | 2003 |
Cytoprotective properties of carboxymethyl cellulose (CMC) when used prior to wearing contact lenses treated with cationic disinfecting agents.
Topics: Biguanides; Biological Availability; Carboxymethylcellulose Sodium; Contact Lens Solutions; Contact Lenses; Cytoprotection; Drug Interactions; Drug Resistance, Bacterial; Microbial Sensitivity Tests; Ophthalmic Solutions; Pseudomonas aeruginosa; Staphylococcus aureus | 2003 |
Persistently culture positive acanthamoeba keratitis: in vivo resistance and in vitro sensitivity.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Amebicides; Animals; Benzamidines; Biguanides; Chlorhexidine; Cornea; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Parasitic Sensitivity Tests; Retrospective Studies; Risk Factors; Treatment Outcome | 2003 |
Acanthamoeba polyphaga strain age and method of cyst production influence the observed efficacy of therapeutic agents and contact lens disinfectants.
Topics: Acanthamoeba; Age Factors; Analysis of Variance; Animals; Antiprotozoal Agents; Biguanides; Chlorhexidine; Colony Count, Microbial; Contact Lens Solutions; Contact Lenses; Disinfection; Hydrogen Peroxide; Propylamines | 2003 |
Determination of biguanide groups in polyhexamethylene biguanide hydrochloride by titrimetric methods.
Topics: Biguanides; Colloids; Disinfectants; Hydrogen-Ion Concentration; Nitrogen; Perchlorates; Potentiometry; Silver Nitrate; Titrimetry | 2003 |
Cooperativity in the binding of the cationic biocide polyhexamethylene biguanide to nucleic acids.
Topics: Anti-Infective Agents; Biguanides; Binding Sites; Cations; Chemical Precipitation; DNA; Escherichia coli; Fluorescence Polarization; Kinetics; RNA, Transfer; Titrimetry | 2004 |
Resistance, biguanide sorption and biguanide-induced pentose leakage during encystment of Acanthamoeba castellanii.
Topics: Acanthamoeba; Amebicides; Animals; Biguanides; Chlorhexidine; Disinfectants; Dose-Response Relationship, Drug; Drug Resistance; Pentoses | 2004 |
Biguanide-induced changes in Acanthamoeba castellanii: an electron microscopic study.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Animals; Biguanides; Cell Membrane; Chlorhexidine; Cytoplasm; Disinfectants; Humans; Life Cycle Stages; Microscopy, Electron; Microscopy, Electron, Scanning | 1998 |
Laser in situ keratomileusis treatment for myopia after Acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Adult; Amebicides; Benzamidines; Biguanides; Contact Lenses, Hydrophilic; Cornea; Disinfectants; Female; Humans; Keratomileusis, Laser In Situ; Myopia | 2004 |
Pseudomonas aeruginosa-induced infection and degradation of human wound fluid and skin proteins ex vivo are eradicated by a synthetic cationic polymer.
Topics: Antimicrobial Cationic Peptides; Biguanides; Colony Count, Microbial; Exudates and Transudates; Humans; Models, Biological; Proteins; Pseudomonas aeruginosa; Pseudomonas Infections; Skin; Wound Infection | 2004 |
[Amniotic membrane transplantation for the treatment severe acanthamoeba keratitis].
Topics: Acanthamoeba Keratitis; Adult; Amnion; Biguanides; Biological Dressings; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Male; Middle Aged; Treatment Outcome; Visual Acuity | 2004 |
Effect of selected wound antiseptics on adult articular cartilage (bovine sesamoid bone) in the presence of Escherichia coli and Staphylococcus aureus.
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Cartilage, Articular; Cattle; Escherichia coli; Imines; Povidone-Iodine; Proteoglycans; Pyridines; Staphylococcus aureus | 2005 |
Amoebicidal activity of multipurpose contact lens solutions.
Topics: Acanthamoeba castellanii; Amebicides; Biguanides; Contact Lens Solutions; Disinfection; Parasitic Sensitivity Tests; Polymers; Propylamines; Time Factors | 2005 |
Novel use of a swimming pool biocide in the treatment of a rare fungal mastoiditis.
Topics: Biguanides; Child; Disinfectants; Humans; Immunocompromised Host; Male; Mastoiditis; Mycoses; Swimming Pools; Water Microbiology | 2005 |
Polybiguanides, particularly polyethylene hexamethylene biguanide, have activity against human immunodeficiency virus type 1.
Topics: Anti-HIV Agents; Anti-Infective Agents; Biguanides; Cell Survival; Dextran Sulfate; Dose-Response Relationship, Drug; HeLa Cells; HIV-1; Humans; Inhibitory Concentration 50; Nonoxynol; Spermatocidal Agents; Structure-Activity Relationship; Virus Replication | 2005 |
Leg ulcer in a patient associated with hydroxyurea therapy.
Topics: Alginates; Antineoplastic Agents; Bandages; Biguanides; Debridement; Glucuronic Acid; Hexuronic Acids; Humans; Hydroxyurea; Isotonic Solutions; Leg Ulcer; Male; Middle Aged; Ringer's Solution; Skin Care; Thrombocythemia, Essential; Ultrasonic Therapy; Wound Healing | 2006 |
[Disseminated herpes zoster in diabetes mellitus].
Topics: Acyclovir; Administration, Topical; Aged; Antiviral Agents; Biguanides; Blood Glucose; Diabetes Mellitus, Type 2; DNA, Viral; Follow-Up Studies; Glycated Hemoglobin; Herpes Zoster; Herpesvirus 3, Human; Humans; Insulin; Male; Ointments; Polymerase Chain Reaction; Time Factors; Treatment Outcome | 2006 |
Comparative study of in vitro cytotoxicity of povidone-iodine in solution, in ointment or in a liposomal formulation (Repithel) and selected antiseptics.
Topics: Administration, Topical; Animals; Anti-Infective Agents, Local; Biguanides; Cell Survival; Chlorhexidine; CHO Cells; Cricetinae; Cricetulus; Fibroblasts; Imines; Liposomes; Mice; Models, Animal; Ointments; Pharmaceutical Solutions; Povidone-Iodine; Pyridines; Time Factors | 2006 |
The response of Escherichia coli to exposure to the biocide polyhexamethylene biguanide.
Topics: Bacterial Outer Membrane Proteins; Biguanides; Disinfectants; DNA Repair; Drug Resistance, Bacterial; Escherichia coli; Escherichia coli Proteins; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Genetic Complementation Test; Mutagenesis, Insertional; Oligonucleotide Array Sequence Analysis; RNA, Bacterial; RNA, Messenger; Transcription, Genetic | 2006 |
The effect of an antibacterial washing-up liquid in reducing dishwater aerobic plate counts.
Topics: Bacteria, Aerobic; Biguanides; Colony Count, Microbial; Cooking and Eating Utensils; Detergents; Disinfectants; Food Microbiology; Water Microbiology | 2006 |
Efficacy of contact lens storage solutions against different acanthamoeba strains.
Topics: Acanthamoeba; Animals; Biguanides; Chlorhexidine; Contact Lens Solutions; Contact Lenses, Hydrophilic; Disinfectants; Disinfection; Drug Therapy, Combination; Equipment Contamination; Time Factors | 2006 |
Biodegradability of end-groups of the biocide polyhexamethylene biguanide (PHMB) assessed using model compounds.
Topics: Amines; Bacteria; Biguanides; Biodegradation, Environmental; Culture Media; Guanidine; Industrial Microbiology; Pseudomonas putida; Species Specificity | 2006 |
A keratitis rat model for evaluation of anti-Acanthamoeba polyphaga agents.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Administration, Topical; Animals; Antiprotozoal Agents; Benzamidines; Betamethasone; Biguanides; Chronic Disease; Corneal Stroma; Disease Models, Animal; Drug Evaluation; Drug Therapy, Combination; Glucocorticoids; Male; Parasitic Sensitivity Tests; Phosphorylcholine; Rats; Rats, Sprague-Dawley; Specific Pathogen-Free Organisms | 2006 |
Unusual case of acanthamoeba keratitis in a contact lens wearer.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Animals; Antiparasitic Agents; Biguanides; Biopsy; Contact Lenses, Hydrophilic; Corneal Stroma; Diagnosis, Differential; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Neomycin | 2006 |
[Preventing nosocomial infections. Dressings soaked in polyhexamethylene biguanide (PHMB)].
Topics: Anti-Bacterial Agents; Bandages; Biguanides; Cross Infection; Humans; Surgical Wound Infection | 2006 |
Polyhexamethylenebiguanide hydrochloride exposure and erythema multiforme in a physician.
Topics: Biguanides; Erythema Multiforme; Female; France; Humans; Middle Aged; Occupational Exposure; Physicians | 2006 |
Acanthamoeba keratitis associated with misuse of daily disposable contact lenses.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Aged; Amebicides; Animals; Benzamidines; Biguanides; Contact Lenses; Disinfectants; Disposable Equipment; Epithelium, Corneal; Follow-Up Studies; Humans; Male; Ophthalmic Solutions | 2006 |
Acanthamoeba keratitis due to Acanthamoeba genotype T4 in a non-contact-lens wearer in Turkey.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Animals; Anti-Bacterial Agents; Antifungal Agents; Antiprotozoal Agents; Benzamidines; Biguanides; Contact Lenses; Disinfectants; Fluconazole; Genotype; Humans; Male; Neomycin; Risk Factors; Turkey | 2007 |
Biocide uptake in contact lenses and loss of fungicidal activity during storage of contact lenses.
Topics: Antifungal Agents; Biguanides; Contact Lens Solutions; Contact Lenses, Hydrophilic; Disinfectants; Equipment Reuse; Fusarium; Patient Compliance | 2006 |
Peritoneal instillation of taurolidine or polihexanide modulates intestinal microcirculation in experimental endotoxemia.
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Disease Models, Animal; Endotoxemia; Gastrointestinal Motility; Instillation, Drug; Intestines; Lipopolysaccharides; Male; Microcirculation; Peritoneal Lavage; Rats; Rats, Inbred Lew; Taurine; Thiadiazines; Treatment Outcome; Vasodilation | 2007 |
Molecular characterization of Acanthamoeba isolated from amebic keratitis related to orthokeratology lens overnight wear.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Animals; Antiprotozoal Agents; Astigmatism; Biguanides; Chlorhexidine; Contact Lenses; Disinfectants; DNA, Mitochondrial; DNA, Protozoan; DNA, Ribosomal; Female; Humans; Itraconazole; Myopia; Parasitic Sensitivity Tests; Polymorphism, Restriction Fragment Length; RNA, Ribosomal, 18S; Sequence Analysis, DNA | 2006 |
[Painless acanthamoeba keratitis].
Topics: Acanthamoeba Keratitis; Adult; Antiprotozoal Agents; Benzamidines; Biguanides; Combined Modality Therapy; Contact Lenses, Extended-Wear; Contact Lenses, Hydrophilic; Cornea; Corneal Transplantation; Diagnosis, Differential; Disinfectants; Drug Therapy, Combination; Humans; Lacrimal Apparatus Diseases; Lenses, Intraocular; Male; Reoperation; Risk Factors | 2007 |
The biocide polyhexamethylene biguanide remains an uncommon contact allergen.
Topics: Biguanides; Cosmetics; Dermatitis, Allergic Contact; Disinfectants; Humans; Patch Tests; Risk Factors | 2007 |
Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells.
Topics: Alkaline Phosphatase; Anti-Bacterial Agents; Anti-Infective Agents, Local; Arthroplasty, Replacement; Bacterial Infections; Biguanides; Bone Cements; Cell Count; Cell Culture Techniques; Cell Survival; Cross Infection; Drug Delivery Systems; Drug Resistance, Bacterial; Endothelial Cells; Gentamicins; Humans; Osteoblasts; Prosthesis-Related Infections | 2007 |
Acanthamoeba keratitis related to orthokeratology.
Topics: Acanthamoeba Keratitis; Adolescent; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Circadian Rhythm; Contact Lenses; Drug Therapy, Combination; Female; Humans; Male; Visual Acuity | 2007 |
[Acanthamoeba keratitis: about the first two Tunisian cases].
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Amebicides; Animals; Antifungal Agents; Benzamidines; Biguanides; Contact Lenses, Hydrophilic; Drug Therapy, Combination; Eye Infections, Fungal; Female; Fusarium; Humans; Keratoplasty, Penetrating; Ketoconazole; Pyrimidines; Triazoles; Tunisia; Voriconazole | 2007 |
Efficacy of contact lens storage solutions against trophozoite and cyst of Acanthamoeba castellanii strain 1BU and their cytotoxic potential on corneal cells.
Topics: Acanthamoeba castellanii; Acanthamoeba Keratitis; Animals; Biguanides; Cell Survival; Cells, Cultured; Contact Lens Solutions; Disinfectants; Epithelium, Corneal; Humans; Parasitic Sensitivity Tests; Rabbits; Trophozoites | 2007 |
Acanthamoeba: keratopathogenicity of isolates from domestic tap water in Korea.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Animals; Biguanides; Cell Line; Chlorhexidine; Contact Lenses; Disinfectants; DNA, Mitochondrial; DNA, Protozoan; DNA, Ribosomal; Epithelium, Corneal; Fresh Water; Humans; Korea; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; RNA, Ribosomal, 18S; Sequence Analysis, DNA; Water Supply | 2007 |
Acanthamoeba keratitis: a parasite on the rise.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Adult; Aged; Animals; Anti-Infective Agents, Local; Antiprotozoal Agents; Biguanides; Contact Lenses; Cornea; Diagnostic Techniques, Ophthalmological; Drug Therapy, Combination; Female; Humans; Incidence; Male; Middle Aged; Philadelphia; Retrospective Studies; Risk Factors; Treatment Outcome; Visual Acuity | 2007 |
Cysticidal effect on acanthamoeba and toxicity on human keratocytes by polyhexamethylene biguanide and chlorhexidine.
Topics: Acanthamoeba castellanii; Amebicides; Animals; Biguanides; Cell Survival; Cells, Cultured; Chlorhexidine; Corneal Stroma; Disinfectants; Fibroblasts; Humans; Microscopy, Electron, Transmission; Microscopy, Phase-Contrast; Parasitic Sensitivity Tests | 2007 |
Superficial corneal "staining"-clinical observation and risk assessment.
Topics: Biguanides; Contact Lens Solutions; Contact Lenses; Disinfectants; Fusarium; Humans; Keratitis; Mycoses; Polymers; Propylamines; Risk Assessment | 2007 |
Visual outcome and rehabilitation in a case of bilateral acanthamoeba sclerokeratitis.
Topics: Acanthamoeba Keratitis; Adult; Benzamidines; Biguanides; Cataract Extraction; Chloramphenicol; Drug Therapy, Combination; Humans; Keratoplasty, Penetrating; Lasers, Solid-State; Lens Capsule, Crystalline; Male; Prednisolone; Prognosis; Scleritis; Visual Acuity | 2007 |
Microbial degradation of the biocide polyhexamethylene biguanide: isolation and characterization of enrichment consortia and determination of degradation by measurement of stable isotope incorporation into DNA.
Topics: Azospirillum; Bacteria; Bacterial Typing Techniques; Biguanides; Biodegradation, Environmental; Culture Media; Disinfectants; DNA, Bacterial; Industrial Microbiology; Nitrogen Radioisotopes; Phylogeny; Sphingomonas | 2007 |
Eradication of methicillin-resistant Staphylococcus aureus in a chronic wound by a new polyhexanide hydrogel.
Topics: Adult; Biguanides; Chronic Disease; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Methicillin Resistance; Staphylococcal Skin Infections; Staphylococcus aureus | 2007 |
Good visual outcome after prompt treatment of acanthamoeba keratitis associated with overnight orthokeratology lens wear.
Topics: Acanthamoeba Keratitis; Benzamidines; Biguanides; Child; Circadian Rhythm; Contact Lens Solutions; Contact Lenses; Cornea; Drug Contamination; Drug Therapy, Combination; Humans; Male; Orthokeratologic Procedures; Visual Acuity | 2007 |
Acanthamoeba keratitis related to cosmetic contact lenses.
Topics: Acanthamoeba Keratitis; Adolescent; Antiprotozoal Agents; Biguanides; Chlorhexidine; Contact Lenses; Cosmetic Techniques; Drug Therapy, Combination; Female; Humans | 2007 |
Cytotoxicity of contact lens multipurpose solutions: role of oxidative stress, mitochondrial activity and P2X7 cell death receptor activation.
Topics: Apoptosis; Biguanides; Cell Line; Cell Membrane; Cell Survival; Conjunctiva; Contact Lens Solutions; Humans; Hydrogen Peroxide; Membrane Potential, Mitochondrial; Mitochondria; Necrosis; Oxidation-Reduction; Oxidative Stress; Preservatives, Pharmaceutical; Quaternary Ammonium Compounds; Reactive Oxygen Species; Receptors, Purinergic P2; Receptors, Purinergic P2X7; Superoxides | 2008 |
Successful treatment of Scedosporium aurantiacum osteomyelitis in an immunocompetent patient.
Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Biguanides; Cellulitis; DNA, Fungal; DNA, Ribosomal; Humans; Immunocompromised Host; Leg Injuries; Male; Mycoses; Osteomyelitis; Pseudomonas aeruginosa; Scedosporium; Sequence Analysis, DNA; Staphylococcus aureus | 2007 |
Effects of multipurpose solutions on corneal epithelial tight junctions.
Topics: Biguanides; Cell Membrane Permeability; Cells, Cultured; Disinfectants; Epithelium, Corneal; Humans; Intercellular Junctions; Membrane Potentials; Microscopy, Confocal; Microscopy, Electron, Transmission | 2008 |
Susceptibility of biofilm Escherichia coli, Salmonella Enteritidis and Staphylococcus aureus to detergents and sanitizers.
Topics: Benzalkonium Compounds; Biguanides; Biofilms; Chlorhexidine; Detergents; Disinfectants; Escherichia coli; Salmonella enteritidis; Sodium Hypochlorite; Staphylococcus aureus | 2007 |
[The vacuum-assisted closure (V.A.C.) and instillation dressing: limb salvage after 3 degrees open fracture with massive bone and soft tissue defect and superinfection].
Topics: Administration, Topical; Adolescent; Biguanides; Debridement; Enterobacter cloacae; Enterobacteriaceae Infections; Femoral Fractures; Fracture Fixation, Intramedullary; Fracture Healing; Fractures, Open; Gram-Negative Bacterial Infections; Humans; Leg Injuries; Limb Salvage; Male; Multiple Trauma; Negative-Pressure Wound Therapy; Pseudomonas Infections; Soft Tissue Injuries; Stenotrophomonas; Suction; Superinfection | 2008 |
Potentiometric titration of polyhexamethylene biguanide hydrochloride with potassium poly(vinyl sulfate) solution using a cationic surfactant-selective electrode.
Topics: Biguanides; Cations; Electrolytes; Indicators and Reagents; Ion-Selective Electrodes; Polyvinyls; Potentiometry; Sensitivity and Specificity; Solutions; Surface-Active Agents; Titrimetry | 2008 |
Rapidly progressive cataract and iris atrophy during treatment of Acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Administration, Topical; Adult; Aged; Antiprotozoal Agents; Atrophy; Benzamidines; Biguanides; Cataract; Cataract Extraction; Chlorhexidine; Disease Progression; Disinfectants; Drug Therapy, Combination; Female; Glaucoma; Humans; Iris; Keratoplasty, Penetrating; Male; Middle Aged; Retrospective Studies; Trabeculectomy | 2008 |
Polyhexamethyl biguanide can eliminate contaminant yeasts from fuel-ethanol fermentation process.
Topics: Biguanides; Culture Media; Drug Resistance, Fungal; Ethanol; Fermentation; Fungicides, Industrial; Glucose; Industrial Microbiology; Saccharomyces cerevisiae; Survival Analysis; Yeasts | 2008 |
Medical treatment for combined Fusarium and Acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Administration, Topical; Adolescent; Adult; Aged; Antifungal Agents; Antiprotozoal Agents; Benzamidines; Biguanides; Child; Clotrimazole; Contact Lenses; Corneal Diseases; Corneal Edema; Corneal Ulcer; Drug Therapy, Combination; Epithelium, Corneal; Eye Injuries; Female; Fusarium; Humans; Keratitis; Male; Mycoses; Natamycin; Retrospective Studies; Young Adult | 2009 |
In vitro study of the effect of cationic biocides on bacterial population dynamics and susceptibility.
Topics: Bacteria; Biguanides; Cations; Chlorhexidine; Disinfectants; DNA Primers; Microbial Sensitivity Tests; Polymerase Chain Reaction; Population Dynamics | 2008 |
Prognostic factors affecting visual outcome in Acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Adult; Antiprotozoal Agents; Benzamidines; Biguanides; Case-Control Studies; Chlorhexidine; Debridement; Disinfectants; Drug Therapy, Combination; Female; Humans; Keratoplasty, Penetrating; Male; Prognosis; Retrospective Studies; Visual Acuity | 2008 |
Rapid antibacterial activity of 2 novel hand soaps: evaluation of the risk of development of bacterial resistance to the antibacterial agents.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bacterial Infections; Benzethonium; Biguanides; Chlorhexidine; Drug Resistance, Bacterial; Farnesol; Gram-Negative Bacteria; Gram-Positive Bacteria; Hand Disinfection; Humans; Microbial Sensitivity Tests; Risk Assessment; Skin; Soaps; Time Factors; Triclosan | 2008 |
Validation of real-time PCR for laboratory diagnosis of Acanthamoeba keratitis.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Animals; Biguanides; DNA Primers; Enzyme Inhibitors; Humans; Parasitology; Polymerase Chain Reaction; Reproducibility of Results; Sensitivity and Specificity | 2008 |
Keratitis by Acanthamoeba triangularis: report of cases and characterization of isolates.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Adult; Animals; Antiprotozoal Agents; Biguanides; DNA, Mitochondrial; DNA, Protozoan; Female; Humans; Male; Phylogeny; Polymorphism, Restriction Fragment Length; RNA, Ribosomal, 16S; RNA, Ribosomal, 18S | 2008 |
Impact of an antimicrobial-impregnated gauze dressing on surgical site infections including methicillin-resistant Staphylococcus aureus infections.
Topics: Bandages; Biguanides; Cross Infection; Disinfectants; Humans; Length of Stay; Methicillin-Resistant Staphylococcus aureus; Prevalence; Staphylococcal Infections; Surgical Wound Infection | 2008 |
[Psoriasis vulgaris as a trigger for a superficial multilocular pyoderma gangrenosum?].
Topics: Biguanides; Dermatologic Agents; Diagnosis, Differential; Humans; Male; Middle Aged; Psoriasis; Pyoderma Gangrenosum | 2009 |
[Treatment of ulcus cruris and other chronic wounds. Waiting can cost the foot].
Topics: Biguanides; Chronic Disease; Drug Therapy, Combination; Humans; Leg Ulcer; Silver; Wound Healing; Wounds and Injuries | 2008 |
[Fournier's gangrene, a battle won. Traditional cures versus a polyhexanide solution].
Topics: Biguanides; Fournier Gangrene; Humans; Male; Middle Aged; Solutions | 2008 |
Clinical evaluation of long-term users of two contact lens care preservative systems.
Topics: Biguanides; Conjunctiva; Contact Lens Solutions; Contact Lenses, Hydrophilic; Cornea; Disinfectants; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Hyperemia; Polymers; Preservatives, Pharmaceutical; Silicones; Single-Blind Method; Tears; Time Factors; Wettability; Xerophthalmia | 2009 |
Do multipurpose solutions damage porcine corneal epithelial cells?
Topics: Animals; Biguanides; Cell Survival; Coloring Agents; Epithelium, Corneal; Flow Cytometry; Kinetics; Polymers; Swine | 2009 |
Bilateral acanthamoeba keratitis after orthokeratology.
Topics: Acanthamoeba Keratitis; Biguanides; Contact Lenses, Extended-Wear; Drug Therapy, Combination; Female; Functional Laterality; Humans; Levofloxacin; Ofloxacin; Orthokeratologic Procedures; Tobramycin; Visual Acuity; Young Adult | 2009 |
[Biodegradable implants and antiseptics for the treatment of postoperative osteomyelitis].
Topics: Absorbable Implants; Administration, Topical; Adult; Aged; Apatites; Biguanides; Collagen; Disinfectants; Drug Combinations; Female; Humans; Male; Middle Aged; Osteomyelitis; Secondary Prevention; Surgical Wound Infection; Treatment Outcome; Young Adult | 2009 |
Cosmetic contact lens-related Acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Benzamidines; Biguanides; Contact Lenses; Cosmetic Techniques; Disinfectants; Female; Humans; Young Adult | 2009 |
A case of descemet's membrane rupture in a patient affected by Acanthamoeba Keratitis.
Topics: Acanthamoeba Keratitis; Adult; Amebiasis; Antiprotozoal Agents; Benzamidines; Biguanides; Corneal Diseases; Corneal Ulcer; Descemet Membrane; Disinfectants; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Microscopy, Acoustic; Ophthalmic Solutions; Rupture, Spontaneous | 2009 |
Topical antimicrobial agents for the treatment of chronic wounds.
Topics: Administration, Topical; Anti-Bacterial Agents; Bandages; Biguanides; Chronic Disease; Disinfectants; Honey; Humans; Iodine; Silver; Wounds and Injuries | 2009 |
Bilateral acanthamoeba keratitis after orthokeratology.
Topics: Acanthamoeba Keratitis; Antiprotozoal Agents; Biguanides; Drug Therapy, Combination; Escherichia coli Infections; Female; Functional Laterality; Humans; Levofloxacin; Microscopy, Phase-Contrast; Ofloxacin; Orthokeratologic Procedures; Tobramycin; Visual Acuity; Young Adult | 2010 |
[A comparative in vitro study of cell toxicity of clinically used antiseptics].
Topics: Anti-Infective Agents, Local; Biguanides; Cell Division; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Fibroblasts; Humans; Imines; In Vitro Techniques; Keratinocytes; Povidone-Iodine; Pyridines | 2009 |
Analysis of polyhexamethylene biguanide in multipurpose contact lens solutions.
Topics: Biguanides; Chromatography, High Pressure Liquid; Contact Lens Solutions; Disinfectants; Drug Stability; Drug Storage; Hydrogen Peroxide; Ophthalmic Solutions; Reproducibility of Results; Solid Phase Extraction; Temperature | 2009 |
Pythium insidiosum keratitis in an Australian child.
Topics: Antifungal Agents; Australia; Biguanides; Child, Preschool; Corneal Transplantation; Corneal Ulcer; Disinfectants; Drug Therapy, Combination; Female; Genes, rRNA; Humans; Pyrimidines; Pythium; Triazoles; Voriconazole | 2009 |
Polyhexamethylene biguanide exposure leads to viral aggregation.
Topics: Biguanides; Disinfectants; Hydrophobic and Hydrophilic Interactions; Levivirus; Viral Proteins | 2010 |
Effect of surfactants, temperature, and sonication on the virucidal activity of polyhexamethylene biguanide against the bacteriophage MS2.
Topics: Antiviral Agents; Biguanides; Disinfectants; Humans; Levivirus; Sonication; Surface-Active Agents; Temperature; Virus Attachment; Virus Diseases; Virus Inactivation | 2010 |
Severe anaphylaxis to the antiseptic polyhexanide.
Topics: Administration, Topical; Aged, 80 and over; Anaphylaxis; Anti-Infective Agents, Local; Biguanides; Female; Humans; Immunoglobulin E; Severity of Illness Index | 2010 |
[Toxicity of antiseptics on chondrocytes in vitro].
Topics: Anti-Infective Agents, Local; Biguanides; Cartilage, Articular; Cell Survival; Cells, Cultured; Chondrocytes; DNA Replication; Dose-Response Relationship, Drug; Humans; Hydrogen Peroxide; In Vitro Techniques; Povidone-Iodine | 2010 |
[Infectious keratitis and cosmetic lenses: a five-case retrospective study].
Topics: Abscess; Acanthamoeba Keratitis; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local; Antifungal Agents; Benzamidines; Biguanides; Blindness; Contact Lenses; Corneal Opacity; Corneal Surgery, Laser; Female; Gentamicins; Humans; Keratitis; Middle Aged; Pseudomonas Infections; Pyrimidines; Retrospective Studies; Risk Factors; Serratia Infections; Staphylococcal Infections; Ticarcillin; Triazoles; Vancomycin; Voriconazole; Young Adult | 2010 |
Contact lens case contamination during daily wear of silicone hydrogels.
Topics: Biguanides; Contact Lens Solutions; Contact Lenses, Hydrophilic; Disinfectants; Equipment Contamination; Fungi; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Propylamines; Silicones | 2010 |
Antimicrobial efficacy of 3 oral antiseptics containing octenidine, polyhexamethylene biguanide, or Citroxx: can chlorhexidine be replaced?
Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bacteria; Biguanides; Candida albicans; Chlorhexidine; Fusobacterium nucleatum; Humans; Imines; Microbial Sensitivity Tests; Pyridines; Streptococcus; Streptococcus mutans | 2010 |
Antiseptic efficacy and tolerance of tissue-tolerable plasma compared with two wound antiseptics on artificially bacterially contaminated eyes from commercially slaughtered pigs.
Topics: Animals; Anti-Infective Agents, Local; Antisepsis; Bacteria; Biguanides; Colony Count, Microbial; Cornea; Plasma Gases; Povidone-Iodine; Pseudomonas aeruginosa; Staphylococcus aureus; Swine; Wounds and Injuries | 2010 |
A practice-oriented recommendation for treatment of critically colonised and locally infected wounds using polihexanide.
Topics: Acute Disease; Bacterial Infections; Biguanides; Chronic Disease; Contraindications; Disinfectants; Humans; Practice Guidelines as Topic; Pressure Ulcer; Wound Healing; Wounds and Injuries | 2010 |
Polihexanide--perspectives on clinical wound antisepsis.
Topics: Anti-Infective Agents, Local; Antisepsis; Biguanides; Drug Resistance, Microbial; Humans; Skin; Wound Infection | 2010 |
Polihexanide for wound treatment--how it began.
Topics: Anti-Infective Agents, Local; Antisepsis; Biguanides; Drug Carriers; Drug Resistance, Microbial; History, 19th Century; History, 20th Century; Humans; Polyethylene Glycols; Skin; Therapeutic Irrigation; Wound Infection | 2010 |
Efficacy of chlorhexidine, polihexanide and tissue-tolerable plasma against Pseudomonas aeruginosa biofilms grown on polystyrene and silicone materials.
Topics: Acridine Orange; Anti-Infective Agents, Local; Biguanides; Biofilms; Chlorhexidine; Gentian Violet; Plasma Gases; Polystyrenes; Pseudomonas aeruginosa; Pseudomonas Infections; Silicones | 2010 |
Response analysis of stimulating efficacy of polihexanide in an in vitro wound model with respiratory ciliary epithelial cells.
Topics: Anti-Infective Agents, Local; Biguanides; Cell Line; Cell Proliferation; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Respiratory System; Wound Healing; Wound Infection | 2010 |
Riboflavin and ultraviolet light a therapy as an adjuvant treatment for medically refractive Acanthamoeba keratitis: report of 3 cases.
Topics: Acanthamoeba Keratitis; Adult; Antiprotozoal Agents; Benzamidines; Biguanides; Chemotherapy, Adjuvant; Chlorhexidine; Contact Lenses, Hydrophilic; Corneal Ulcer; Drug Therapy, Combination; Humans; Male; Microscopy, Confocal; Middle Aged; Photochemotherapy; Photosensitizing Agents; Riboflavin; Ultraviolet Rays; Visual Acuity | 2011 |
Structure-activity relationships of polybiguanides with activity against human immunodeficiency virus type 1.
Topics: Animals; Anti-HIV Agents; Anti-Infective Agents; Biguanides; Cell Line; Dose-Response Relationship, Drug; HeLa Cells; HIV Infections; HIV-1; Humans; Mice; Models, Animal; Models, Molecular; Molecular Conformation; Molecular Structure; Polyethylenes; Structure-Activity Relationship | 2010 |
Bactericidal core-shell paramagnetic nanoparticles functionalized with poly(hexamethylene biguanide).
Topics: Animals; Anti-Bacterial Agents; Bacteria; Biguanides; Cell Line; Humans; Magnetite Nanoparticles; Male; Materials Testing; Mice; Polyethyleneimine; Siloxanes | 2011 |
Clinical trial of 0.02% polyhexamethylene biguanide versus placebo in the treatment of microsporidial keratoconjunctivitis.
Topics: Administration, Topical; Biguanides; Disinfectants; Double-Blind Method; Eye Infections, Fungal; Humans; Keratoconjunctivitis; Microsporida; Microsporidiosis; Ophthalmic Solutions; Treatment Outcome; Visual Acuity | 2011 |
Antimicrobial activity of clinically used antiseptics and wound irrigating agents in combination with wound dressings.
Topics: Anti-Infective Agents, Local; Bandages; Biguanides; Imines; In Vitro Techniques; Microbial Sensitivity Tests; Povidone-Iodine; Pyridines; Staphylococcus aureus; Therapeutic Irrigation; Wound Infection | 2011 |
Toxicity of antiseptics against chondrocytes: what is best for the cartilage in septic joint surgery?
Topics: Anti-Infective Agents, Local; Arthritis, Infectious; Biguanides; Cartilage, Articular; Cell Count; Cell Survival; Cells, Cultured; Chondrocytes; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Osteoarthritis, Knee; Taurine; Therapeutic Irrigation; Thiadiazines | 2011 |
Effects of ionic and surfactant agents on the antimicrobial activity of polyhexamethylene biguanide.
Topics: Anti-Infective Agents; Bacteria; Biguanides; Candida albicans; Dose-Response Relationship, Drug; Drug Interactions; Fungi; Poloxamer; Propylene Glycol; Sodium Chloride; Staphylococcus aureus; Surface-Active Agents; Time Factors | 2011 |
[Trailing the footpath of Acanthamoeba keratitis].
Topics: Acanthamoeba Keratitis; Biguanides; Chlorhexidine; Contact Lens Solutions; Contact Lenses, Hydrophilic; Disease Outbreaks; Disinfectants; Early Diagnosis; Humans | 2010 |
[Characteristic appearance of early-stage Acanthamoeba keratitis].
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Adrenal Cortex Hormones; Adult; Biguanides; Cornea; Female; Humans; Male; Natamycin; Prognosis; Retrospective Studies; Severity of Illness Index; Vision, Ocular; Young Adult | 2010 |
Reduced cytotoxicity of polyhexamethylene biguanide hydrochloride (PHMB) by egg phosphatidylcholine while maintaining antimicrobial efficacy.
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Cell Line; Liposomes; Mice; Microbial Sensitivity Tests; Ovum; Phosphatidylcholines; Pseudomonas aeruginosa; Staphylococcus aureus | 2011 |
Importance of porins for biocide efficacy against Mycobacterium smegmatis.
Topics: Biguanides; Disinfectants; Gene Deletion; Imines; Microbial Viability; Mycobacterium smegmatis; Oxazines; Oxazoles; Porins; Pyridines; Staining and Labeling; Thiazoles; Triazines; Xanthenes | 2011 |
Influence of topically applied antimicrobial agents on muscular microcirculation.
Topics: 2-Propanol; Administration, Topical; Animals; Anti-Infective Agents, Local; Arterioles; Biguanides; Capillaries; Ethacridine; Ethanol; Hydrogen Peroxide; Imines; Imipenem; Male; Microcirculation; Muscle, Skeletal; Pyridines; Rats; Rats, Wistar | 2011 |
Intraocular invasion by microsporidial spores in a case of stromal keratitis.
Topics: Acyclovir; Adult; Biguanides; Corneal Stroma; Corneal Ulcer; Drug Therapy, Combination; Endothelium, Corneal; Eye Infections, Fungal; Female; Humans; Intraocular Pressure; Keratoplasty, Penetrating; Microsporidia; Microsporidiosis; Prednisolone; Visual Acuity | 2011 |
Classification of wounds at risk and their antimicrobial treatment with polihexanide: a practice-oriented expert recommendation.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local; Biguanides; Humans; Immunocompetence; Immunocompromised Host; Risk Assessment; Risk Factors; Wound Infection; Wounds and Injuries | 2011 |
Toxicity of polyhexanide and hydrogen peroxide on human chondrocytes in vitro.
Topics: Anti-Infective Agents, Local; Biguanides; Cell Count; Cell Death; Cell Survival; Cells, Cultured; Chondrocytes; Humans; Hydrogen Peroxide; L-Lactate Dehydrogenase; Wound Healing | 2011 |
Clinical evaluation of a PHMB-impregnated biocellulose dressing on paediatric lacerations.
Topics: Bandages; Bicycling; Biguanides; Biocompatible Materials; Cellulose; Child; Child, Preschool; Disinfectants; Female; Foot Injuries; Heel; Humans; Lacerations; Male; Netherlands; Wound Healing | 2011 |
Efficacy of miltefosine for topical treatment of Acanthamoeba keratitis in Syrian hamsters.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Administration, Topical; Animals; Antiprotozoal Agents; Benzamidines; Biguanides; Cricetinae; Disease Models, Animal; Humans; Male; Mesocricetus; Phosphorylcholine; Treatment Outcome | 2012 |
Determination of polyhexamethylene biguanide hydrochloride using photometric colloidal titration with crystal violet as a color indicator.
Topics: Biguanides; Colloids; Coloring Agents; Gentian Violet; Indicators and Reagents; Photometry; Titrimetry | 2011 |
Polyhexamethylene biguanide and calcineurin inhibitors as novel antifungal treatments for Aspergillus keratitis.
Topics: Amphotericin B; Animals; Aspergillosis; Aspergillus fumigatus; Biguanides; Calcineurin Inhibitors; Corneal Ulcer; Cyclosporine; Disinfectants; Drug Synergism; Eye Infections, Fungal; Immunosuppressive Agents; Male; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Prospective Studies; Pyrimidines; Tacrolimus; Triazoles; Voriconazole | 2011 |
The resistance of the yeast Saccharomyces cerevisiae to the biocide polyhexamethylene biguanide: involvement of cell wall integrity pathway and emerging role for YAP1.
Topics: Biguanides; Cell Wall; Disinfectants; Drug Resistance, Fungal; Gene Expression; Promoter Regions, Genetic; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Signal Transduction; Transcription Factors | 2011 |
Assessment of effects of multipurpose contact lens care solutions on human corneal epithelial cells.
Topics: Biguanides; Blotting, Western; Contact Lens Solutions; Disinfectants; Epithelial Cells; Epithelium, Corneal; Humans; Mucins; Polymers | 2011 |
Preferred use of polyhexanide in orthopedic surgery.
Topics: Annexin A5; Anti-Infective Agents, Local; Apoptosis; Biguanides; Biomarkers; Caspases; Cells, Cultured; Chondrocytes; Dactinomycin; Flow Cytometry; Humans; Microscopy, Fluorescence; Orthopedic Procedures | 2011 |
Environmental fate of polyhexamethylene biguanide.
Topics: Anti-Bacterial Agents; Biguanides; Environmental Monitoring; Equipment and Supplies; Fresh Water; Kinetics; Soil; Soil Pollutants; Water Pollutants, Chemical | 2012 |
Investigation of lysine acrylate containing poly(N-isopropylacrylamide) hydrogels as wound dressings in normal and infected wounds.
Topics: Acrylamides; Acrylates; Acrylic Resins; Animals; Anti-Bacterial Agents; Bandages; Biguanides; Disinfectants; Hydrogels; Lysine; Male; Mice; NIH 3T3 Cells; Polymers; Rats; Rats, Sprague-Dawley; Wound Healing; Wound Infection | 2012 |
Cytotoxicity and effects on metabolism of contact lens care solutions on human corneal epithelium cells.
Topics: Biguanides; Cell Line; Cell Membrane; Cell Survival; Contact Lens Solutions; Energy Metabolism; Epithelial Cells; Epithelium, Corneal; Humans; Necrosis; Polymers; Preservatives, Pharmaceutical | 2012 |
Use of 5-cyano-2,3-ditolyl-tetrazolium chloride staining as an indicator of biocidal activity in a rapid assay for anti-Acanthamoeba agents.
Topics: Acanthamoeba castellanii; Biguanides; Disinfectants; Fluorometry; Humans; Microbial Viability; Parasitic Sensitivity Tests; Staining and Labeling; Tetrazolium Salts | 2012 |
A preservative-and-fluorescein interaction model for benign multipurpose solution-associated transient corneal hyperfluorescence.
Topics: Biguanides; Cells, Cultured; Contact Lens Solutions; Disinfectants; Drug Interactions; Epithelium, Corneal; Fluorescein; Fluorescence Polarization; Humans; Liposomes; Polymers; Preservatives, Pharmaceutical | 2012 |
Diagnosis, clinical features and treatment outcome of microsporidial keratoconjunctivitis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biguanides; Child; Disinfectants; Eye Infections, Fungal; Female; Humans; India; Keratoconjunctivitis; Lubricants; Male; Microsporidia; Microsporidiosis; Middle Aged; Retrospective Studies; Seasons; Treatment Outcome | 2012 |
Layer-by-layer assembly of antibacterial coating on interbonded 3D fibrous scaffolds and its cytocompatibility assessment.
Topics: Animals; Anti-Bacterial Agents; Biguanides; Cell Count; Cell Death; Cell Survival; Cells, Cultured; Coated Materials, Biocompatible; Escherichia coli; Fibroblasts; Materials Testing; Microbial Sensitivity Tests; Microscopy, Confocal; Polyesters; Rats; Spectroscopy, Fourier Transform Infrared; Tissue Scaffolds | 2012 |
Benefit of polyhexamethylene biguanide in Fusarium keratitis.
Topics: Adult; Antifungal Agents; Benzamidines; Biguanides; Contact Lenses, Hydrophilic; Corneal Ulcer; Disinfectants; Drug Therapy, Combination; Eye Infections, Fungal; Female; Fungi; Fusariosis; Fusarium; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Natamycin; Pyrimidines; Triazoles; Voriconazole | 2012 |
Akwaton, polyhexamethylene-guanidine hydrochloride-based sporicidal disinfectant: a novel tool to fight bacterial spores and nosocomial infections.
Topics: Bacillus subtilis; Bacterial Infections; Bacteriological Techniques; Biguanides; Cross Infection; Disinfectants; Glass; Linear Models; Microbial Sensitivity Tests; Spores, Bacterial; Stainless Steel; Surface Properties; Time Factors | 2012 |
Antimicrobial properties of cyclodextrin-antiseptics-complexes determined by microplate laser nephelometry and ATP bioluminescence assay.
Topics: Adenosine Triphosphate; Anti-Infective Agents; Biguanides; Candida albicans; Chlorhexidine; Cyclodextrins; Iodine; Lasers; Luminescent Measurements; Malassezia; Nephelometry and Turbidimetry | 2012 |
Clinical use of the antiseptic polihexanide for genital tract infections.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Clindamycin; Female; Humans; Male; Papillomaviridae; Papillomavirus Infections; Prospective Studies; Randomized Controlled Trials as Topic; Reproductive Tract Infections | 2012 |
Co-isolation of Vahlkampfia and acanthamoeba in acanthamoeba-like keratitis in a Spanish population.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Antifungal Agents; Antiprotozoal Agents; Benzamidines; Biguanides; Cell Line; Disinfectants; DNA, Protozoan; Drug Therapy, Combination; Female; Gene Amplification; Genotyping Techniques; Humans; Incidence; Male; Middle Aged; Polymerase Chain Reaction; Pyrimidines; Retrospective Studies; RNA, Ribosomal, 18S; Schizopyrenida; Spain; Triazoles; Voriconazole; Young Adult | 2013 |
Limited use of antiseptics in septic surgery.
Topics: Annexin A5; Anti-Infective Agents, Local; Apoptosis; Biguanides; Caspases; Cells, Cultured; Chlorhexidine; Chondrocytes; Flow Cytometry; Humans; Hydrogen Peroxide; Joint Diseases; Microscopy, Fluorescence; Orthopedic Procedures; Propidium; Sepsis; Surgical Wound Infection | 2012 |
The effect of a wound care solution containing polyhexanide and betaine on bacterial counts: results of an in vitro study .
Topics: Betaine; Biguanides; Colony Count, Microbial; Humans; In Vitro Techniques; Wounds and Injuries | 2012 |
Microbial keratitis following vegetative matter injury.
Topics: Acanthamoeba; Adult; Amebiasis; Amikacin; Anti-Bacterial Agents; Biguanides; Corneal Ulcer; Disinfectants; Eye Infections, Bacterial; Eye Infections, Fungal; Eye Injuries; Female; Humans; Keratitis; Male; Plants; Prevalence; Retrospective Studies; Risk Factors | 2013 |
The effects of contact lens materials on a multipurpose contact lens solution disinfection activity against Staphylococcus aureus.
Topics: Biguanides; Colony Count, Microbial; Contact Lens Solutions; Contact Lenses, Hydrophilic; Disinfectants; Eye Infections, Bacterial; Hydrogels; Silicones; Staphylococcus aureus | 2012 |
Impact of contact lens materials on multipurpose contact lens solution disinfection activity against Fusarium solani.
Topics: Biguanides; Colony Count, Microbial; Contact Lens Solutions; Contact Lenses, Hydrophilic; Disinfectants; Eye Infections, Fungal; Fusariosis; Fusarium | 2012 |
Prognostic factors associated with the need for surgical treatments in acanthamoeba keratitis.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Benzamidines; Biguanides; Biological Dressings; Cornea; Disinfectants; DNA, Protozoan; Drug Therapy, Combination; Eye Evisceration; Female; Humans; Keratoplasty, Penetrating; Male; Microscopy, Confocal; Middle Aged; Polymerase Chain Reaction; Prognosis; Retrospective Studies; Risk Factors; Visual Acuity; Young Adult | 2013 |
Assessment of the mode of action of polyhexamethylene biguanide against Listeria innocua by Fourier transformed infrared spectroscopy and fluorescence anisotropy analysis.
Topics: Biguanides; Cell Membrane; Diphenylhexatriene; Disinfectants; Fluorescence Polarization; Lipid Bilayers; Listeria; Membrane Fluidity; Phospholipids; Spectroscopy, Fourier Transform Infrared | 2012 |
Interaction of polyhexamethylene biguanide hydrochloride (PHMB) with phosphatidylcholine containing o/w emulsion and consequences for microbicidal efficacy and cytotoxicity.
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Cell Line; Cell Survival; Drug Delivery Systems; Emulsions; Fibroblasts; Mice; Microbial Sensitivity Tests; Phosphatidylcholines; Pseudomonas aeruginosa; Staphylococcus aureus | 2013 |
Successful management of a massive residual space empyema using intrathoracic vacuum-assisted instillation.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Empyema, Pleural; Humans; Lung Neoplasms; Male; Negative-Pressure Wound Therapy; Pneumonectomy; Pseudomonas aeruginosa; Pseudomonas Infections; Surgical Flaps; Thoracostomy; Time Factors; Tomography, X-Ray Computed; Treatment Outcome | 2013 |
In-vitro analysis of the effect of gentamicin and polyhexanide on bone tissue.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Bone and Bones; Female; Gentamicins; In Vitro Techniques; Microscopy, Electron, Transmission; Models, Animal; Rabbits; Time Factors | 2013 |
Cytotoxic effects of polyhexanide on cellular repopulation and calcification of decellularized equine carotids in vitro and in vivo.
Topics: Animals; Biguanides; Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Carotid Arteries; Disinfectants; Endothelial Cells; Endothelium, Vascular; Horses; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Tissue Engineering | 2013 |
Enzyme responsive hyaluronic acid nanocapsules containing polyhexanide and their exposure to bacteria to prevent infection.
Topics: Anti-Bacterial Agents; Biguanides; Drug Carriers; Escherichia coli; Escherichia coli Infections; Humans; Hyaluronic Acid; Nanocapsules; Staphylococcal Infections; Staphylococcus aureus | 2013 |
Acanthamoeba lenticulata keratitis in a hard contact lens wearer.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Antiprotozoal Agents; Benzamidines; Biguanides; Contact Lenses; DNA, Protozoan; Drug Therapy, Combination; Epithelium, Corneal; Humans; Keratoplasty, Penetrating; Male; RNA, Ribosomal, 18S | 2013 |
Evaluation of polyhexamethylene biguanide (PHMB) as a disinfectant for adenovirus.
Topics: Adenovirus Infections, Human; Adenoviruses, Human; Biguanides; Disease Transmission, Infectious; Disinfectants; Eye Infections, Viral; Humans; Swimming Pools; Viral Load; Viral Plaque Assay | 2013 |
Antimicrobial electrospun membranes of chitosan/poly(ethylene oxide) incorporating poly(hexamethylene biguanide) hydrochloride.
Topics: Anti-Bacterial Agents; Biguanides; Calorimetry, Differential Scanning; Carbohydrate Conformation; Chitosan; Disk Diffusion Antimicrobial Tests; Electrochemical Techniques; Escherichia coli; Kinetics; Membranes, Artificial; Nanocomposites; Nanofibers; Polyethylene Glycols; Porosity; Spectroscopy, Fourier Transform Infrared; Staphylococcus aureus; Viscosity | 2013 |
Miltefosine and polyhexamethylene biguanide: a new drug combination for the treatment of Acanthamoeba keratitis.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Animals; Antiprotozoal Agents; Biguanides; Cell Line; Cell Proliferation; Disease Models, Animal; Disinfectants; Drug Therapy, Combination; Fibroblasts; Male; Phosphorylcholine; Rats; Rats, Wistar | 2014 |
Antibacterial properties of cyclodextrin-antiseptics-complexes determined by microplate laser nephelometry and ATP bioluminescence assay.
Topics: Adenosine Triphosphate; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bacteria; Biguanides; Chlorhexidine; Cyclodextrins; Iodine; Luminescent Measurements; Nephelometry and Turbidimetry | 2013 |
Bacterial growth kinetics under a novel flexible methacrylate dressing serving as a drug delivery vehicle for antiseptics.
Topics: Animals; Anti-Infective Agents, Local; Bandages; Betaine; Biguanides; Disinfectants; Drug Delivery Systems; Drug Synergism; Ethylene Glycols; Imines; Kinetics; Methicillin-Resistant Staphylococcus aureus; Povidone-Iodine; Pyridines; Swine; Time Factors; Wound Healing; Wounds and Injuries | 2013 |
Ex vivo porcine vaginal mucosal model of infection for determining effectiveness and toxicity of antiseptics.
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Female; Microbial Sensitivity Tests; Models, Biological; Mucous Membrane; Povidone-Iodine; Staphylococcus aureus; Swine; Tissue Culture Techniques; Vagina | 2013 |
In vitro comparison of the effectiveness of polihexanide and chlorhexidine against canine isolates of Staphylococcus pseudintermedius, Pseudomonas aeruginosa and Malassezia pachydermatis.
Topics: Animals; Biguanides; Chlorhexidine; Disinfectants; Dog Diseases; Dogs; Malassezia; Pseudomonas aeruginosa; Skin Diseases, Bacterial; Staphylococcus | 2013 |
Application of topical negative pressure for traumatic amputations.
Topics: Amputation, Traumatic; Biguanides; Debridement; Disinfectants; Humans; Negative-Pressure Wound Therapy; Occlusive Dressings | 2013 |
Demodex folliculitis presenting as periocular vesiculopustular rash.
Topics: Aged; Animals; Anti-Bacterial Agents; Biguanides; Blepharitis; Disinfectants; Drug Therapy, Combination; Erythromycin; Female; Folliculitis; Glycols; Hexanes; Humans; Mite Infestations; Mites; Octanols; Ointments; Skin Diseases, Vesiculobullous | 2013 |
Raman microspectroscopy analysis in the treatment of acanthamoeba keratitis.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Amebicides; Biguanides; Contact Lenses; Cytoplasm; Humans; Models, Biological; Multivariate Analysis; Principal Component Analysis; Single-Cell Analysis; Spectrum Analysis, Raman | 2013 |
Development of a practical complete-kill assay to evaluate anti-Acanthamoeba drugs.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Antiprotozoal Agents; Benzamidines; Biguanides; Chlorhexidine; Disinfectants; Humans; Parasitic Sensitivity Tests; Pyrimidines; Triazoles; Voriconazole | 2013 |
Human osteoblast damage after antiseptic treatment.
Topics: Anti-Infective Agents, Local; Biguanides; Cell Survival; Cells, Cultured; Chlorhexidine; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; L-Lactate Dehydrogenase; Osteoblasts | 2014 |
Antimicrobial activity of short- and medium-term applications of polyhexamethylene biguanide, chlorhexidine digluconate and calcium hydroxide in infected immature bovine teeth in vitro.
Topics: Animals; Anti-Infective Agents; Biguanides; Calcium Hydroxide; Cattle; Chlorhexidine; Colony Count, Microbial; In Vitro Techniques; Incisor | 2014 |
Surgery for acquired cardiovascular disease: antiseptic treatment of contaminated vein grafts.
Topics: Anti-Infective Agents, Local; Antisepsis; Biguanides; Humans; Imines; Operating Rooms; Povidone-Iodine; Prosthesis-Related Infections; Pyridines; Saphenous Vein; Staphylococcal Infections; Staphylococcus; Stress, Mechanical; Tensile Strength; Time Factors; Tissue and Organ Harvesting; Treatment Outcome | 2014 |
Activity of the antiseptic polyhexanide against gram-negative bacteria.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; beta-Lactams; Biguanides; Ciprofloxacin; Drug Combinations; Escherichia coli; Gentamicins; Haemophilus influenzae; Klebsiella pneumoniae; Microbial Sensitivity Tests; Microbial Viability; Moraxella catarrhalis; Pseudomonas aeruginosa | 2014 |
Biofilm-forming activity of bacteria isolated from toilet bowl biofilms and the bactericidal activity of disinfectants against the isolates.
Topics: Bacteria; Bacterial Physiological Phenomena; Biguanides; Biofilms; Biota; Disinfectants; Environmental Microbiology; Japan; Quaternary Ammonium Compounds; Seasons | 2013 |
The effect of negative pressure wound therapy with periodic instillation using antimicrobial solutions on Pseudomonas aeruginosa biofilm on porcine skin explants.
Topics: Animals; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Biofilms; Chlorhexidine; Microscopy, Electron, Scanning; Models, Animal; Negative-Pressure Wound Therapy; Polyethylenes; Povidone-Iodine; Pseudomonas aeruginosa; Pseudomonas Infections; Quaternary Ammonium Compounds; Skin; Sodium Chloride; Swine; Therapeutic Irrigation; Wound Healing | 2013 |
In-vitro activity of polyhexanide alone and in combination with antibiotics against Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Drug Synergism; Electrophoresis, Gel, Pulsed-Field; Genotype; Humans; Microbial Sensitivity Tests; Molecular Typing; Staphylococcus aureus | 2014 |
W.A.R. scores in patients with chronic leg ulcers: results of a multicentre study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Biguanides; Child; Chronic Disease; Feasibility Studies; Female; Germany; Humans; Incidence; Leg Ulcer; Male; Middle Aged; Patient Selection; Risk Assessment; Wound Infection | 2014 |
Antisepsis with polyhexanide is effective against endophthalmitis after intravitreal injections.
Topics: Angiogenesis Inhibitors; Anti-Bacterial Agents; Antisepsis; Biguanides; Endophthalmitis; Eye Infections, Bacterial; Follow-Up Studies; Humans; Intravitreal Injections; Retrospective Studies; Vascular Endothelial Growth Factor A | 2014 |
Recent cluster of childhood microbial keratitis due to orthokeratology.
Topics: Acanthamoeba Keratitis; Adolescent; Anti-Bacterial Agents; Biguanides; Cephalothin; Child; Chlorhexidine; Cluster Analysis; Corneal Ulcer; Disinfectants; Drug Therapy, Combination; Eye Infections, Bacterial; Humans; Male; Ofloxacin; Orthokeratologic Procedures; Pseudomonas Infections | 2014 |
Selection of an optimal antiseptic solution for intraoperative irrigation: an in vitro study.
Topics: Anti-Infective Agents, Local; Biguanides; Cell Survival; Chlorhexidine; Fibroblasts; Humans; Hydrogen Peroxide; Imines; Intraoperative Care; Mesenchymal Stem Cells; Povidone-Iodine; Pyridines; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis; Therapeutic Irrigation | 2014 |
The impact of negative-pressure wound therapy with instillation compared with standard negative-pressure wound therapy: a retrospective, historical, cohort, controlled study.
Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Betaine; Biguanides; Chronic Disease; Cohort Studies; Debridement; Female; Humans; Male; Middle Aged; Negative-Pressure Wound Therapy; Retrospective Studies; Surface-Active Agents; Therapeutic Irrigation; Wound Healing; Wound Infection; Young Adult | 2014 |
The impact of topical corticosteroid use before diagnosis on the outcome of Acanthamoeba keratitis.
Topics: Acanthamoeba Keratitis; Administration, Topical; Adolescent; Adult; Antiprotozoal Agents; Biguanides; Chlorhexidine; Cohort Studies; Drug Therapy, Combination; Female; Glucocorticoids; Humans; Male; Microscopy, Confocal; Middle Aged; Pentamidine; Treatment Outcome; Visual Acuity; Young Adult | 2014 |
Poly (hexamethylene biguanide) adsorption on hydrogen peroxide treated Ti-Al-V alloys and effects on wettability, antimicrobial efficacy, and cytotoxicity.
Topics: Adsorption; Alloys; Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Biofilms; Cell Line, Tumor; Cell Proliferation; Escherichia coli; Humans; Hydrogen Peroxide; Osteoblasts; Pseudomonas aeruginosa; Staphylococcus aureus; Staphylococcus epidermidis; Titanium; Wettability | 2014 |
Polyhexamethylene biguanide is a relevant sensitizer in wet wipes.
Topics: Adult; Biguanides; Household Products; Humans; Male; Patch Tests; Skin Care | 2014 |
Polyhexanide-containing solution reduces ciliary beat frequency of human nasal epithelial cells in vitro.
Topics: Adult; Anti-Infective Agents, Local; Biguanides; Cell Count; Cilia; Epithelial Cells; Female; Humans; In Vitro Techniques; Male; Nasal Mucosa; Solutions; Young Adult | 2015 |
Transient and sustained bacterial adaptation following repeated sublethal exposure to microbicides and a novel human antimicrobial peptide.
Topics: Adaptation, Physiological; Anti-Infective Agents; Bacteria; Biguanides; Biofilms; Chlorhexidine; Humans; Microbial Sensitivity Tests; Triclosan | 2014 |
Cytokine expression in human osteoblasts after antiseptic treatment: a comparative study between polyhexanide and chlorhexidine.
Topics: Adult; Anti-Infective Agents, Local; Biguanides; Bone Marrow; Cell Adhesion; Cell Shape; Cells, Cultured; Chemokines; Chlorhexidine; Cytokines; Drug Evaluation, Preclinical; Humans; Intercellular Signaling Peptides and Proteins; Osteoarthritis, Knee; Osteoblasts | 2015 |
Comparative study of lens solutions' ability to remove tear constituents.
Topics: Biguanides; Contact Lens Solutions; Contact Lenses, Hydrophilic; Eye Proteins; Humans; Hydrogels; Hydrogen Peroxide; Lubricant Eye Drops; Microscopy, Atomic Force; Silicones; Tears | 2014 |
Study of epigenetic properties of Poly(HexaMethylene Biguanide) hydrochloride (PHMB).
Topics: Animals; Biguanides; Caco-2 Cells; Cell Communication; Cell Line; Cytokines; Disinfectants; Epigenesis, Genetic; Gap Junctions; Hep G2 Cells; Humans; Mice; Mutagenicity Tests; Nucleic Acids | 2014 |
Evaluation of the effectiveness of a polyhexanide and propyl betaine-based gel in the treatment of chronic wounds.
Topics: Administration, Cutaneous; Adolescent; Adult; Aged; Aged, 80 and over; Betaine; Biguanides; Child; Child, Preschool; Chronic Disease; Debridement; Dermatologic Agents; Drug Combinations; Female; Gels; Humans; Infant; Infant, Newborn; Italy; Male; Middle Aged; Occlusive Dressings; Pain Measurement; Treatment Outcome; Wound Healing; Wounds and Injuries | 2014 |
Effects of contact lens solution disinfectants against filamentous fungi.
Topics: Antifungal Agents; Aspergillus flavus; Biguanides; Cetylpyridinium; Chlorhexidine; Contact Lens Solutions; Disinfectants; Fusarium; Microbial Sensitivity Tests; Thimerosal | 2014 |
The effect of mouthwashes containing biguanides on the progression of erosion in dentin.
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Cattle; Chlorhexidine; Citric Acid; Dentin; Disease Progression; Microbial Collagenase; Mouthwashes; Sodium Fluoride; Tooth Demineralization; Tooth Erosion; Tooth Remineralization | 2014 |
[Suspected anaphylaxis by wound treatment with polyhexanide derivate wound products].
Topics: Aged; Anaphylaxis; Biguanides; Disinfectants; Female; Humans; Leg Ulcer | 2014 |
Antimicrobial-impregnated dressing combined with negative-pressure wound therapy increases split-thickness skin graft engraftment: a simple effective technique.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Bandages; Biguanides; Chronic Disease; Female; Graft Survival; Humans; Male; Middle Aged; Negative-Pressure Wound Therapy; Retrospective Studies; Skin Transplantation; Skin Ulcer; Wounds and Injuries | 2015 |
pH influence on antibacterial efficacy of common antiseptic substances.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Chlorhexidine; Hydrogen-Ion Concentration; Imines; Povidone-Iodine; Pseudomonas aeruginosa; Pyridines; Staphylococcus aureus | 2015 |
Polybiguanide (PHMB) loaded in PLA scaffolds displaying high hydrophobic, biocompatibility and antibacterial properties.
Topics: Animals; Anti-Bacterial Agents; Bacterial Adhesion; Biguanides; Biocompatible Materials; Calorimetry; Cell Adhesion; Cell Death; Cell Proliferation; Chlorhexidine; Dogs; Escherichia coli; Fibroblasts; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Madin Darby Canine Kidney Cells; Materials Testing; Microbial Sensitivity Tests; Micrococcus luteus; Polyesters; Polystyrenes; Spectroscopy, Fourier Transform Infrared; Temperature; Tissue Scaffolds | 2015 |
Evaluation of angiogenesis, epithelialisation and microcirculation after application of polyhexanide, chitosan and sodium chloride in rodents.
Topics: Animals; Biguanides; Chitosan; Mice; Microcirculation; Rodentia; Skin; Sodium Chloride; Wound Healing | 2016 |
Toxic indole alkaloids avrainvillamide and stephacidin B produced by a biocide tolerant indoor mold Aspergillus westerdijkiae.
Topics: Animals; Apoptosis; Aspergillus; Biguanides; Cell Line; Drug Resistance, Multiple, Fungal; Environmental Illness; Fungicides, Industrial; Guanidines; Humans; Indole Alkaloids; Indoles; Kidney Tubules; Male; Membrane Potential, Mitochondrial; Molecular Weight; Mycotoxins; Sperm Motility; Sus scrofa | 2015 |
Diffusion of Antimicrobials Across Silicone Hydrogel Contact Lenses.
Topics: Amphotericin B; Anti-Infective Agents; Biguanides; Colony Count, Microbial; Contact Lenses, Hydrophilic; Diffusion; Fluoroquinolones; Hydrogel, Polyethylene Glycol Dimethacrylate; Moxifloxacin; Saccharomyces cerevisiae; Silicones; Spectrophotometry; Staphylococcus epidermidis | 2015 |
Evaluation of the efficacy of antibacterial medical gloves in the ICU setting.
Topics: Anti-Bacterial Agents; Biguanides; Colony Count, Microbial; Cross Infection; Gloves, Protective; Gloves, Surgical; Hand; Humans; Infection Control; Intensive Care Units | 2015 |
[Destructive chondrolysis following intraarticular application of lavasorb (polihexanid) for treatment of knee empyema].
Topics: Adult; Anterior Cruciate Ligament Reconstruction; Arthritis, Infectious; Arthroscopy; Biguanides; Cartilage, Articular; Humans; Male; Menisci, Tibial; Multimodal Imaging; Postoperative Complications; Reoperation; Staphylococcal Infections; Surgical Wound Infection; Therapeutic Irrigation; Tomography, Emission-Computed, Single-Photon; Tomography, X-Ray Computed | 2015 |
Understanding the biocide action of poly(hexamethylene biguanide) using Langmuir monolayers of dipalmitoyl phosphatidylglycerol.
Topics: Biguanides; Phosphatidylglycerols; Surface Properties | 2015 |
Interaction and effectiveness of antimicrobials along with healing-promoting agents in a novel biocellulose wound dressing.
Topics: Anti-Bacterial Agents; Bacteria; Bandages; Biguanides; Cellulose; Re-Epithelialization; Wound Healing; Wound Infection | 2015 |
Contact lens care solution killing efficacy against Acanthamoeba castellanii by in vitro testing and live-imaging.
Topics: Acanthamoeba castellanii; Acanthamoeba Keratitis; Amebiasis; Amebicides; Animals; Biguanides; Contact Lens Solutions; Disinfection; Drug Combinations; Hydrogen Peroxide; Parasitic Sensitivity Tests; Polymers; Propylamines; Reference Standards; Trophozoites | 2015 |
Effects of Polyhexamethylene Biguanide and Polyquaternium-1 on Phospholipid Bilayer Structure and Dynamics.
Topics: Biguanides; Disinfectants; Lipid Bilayers; Models, Molecular; Molecular Conformation; Phospholipids; Polymers; Unilamellar Liposomes | 2015 |
Effects of Formulation on Microbicide Potency and Mitigation of the Development of Bacterial Insusceptibility.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Benzalkonium Compounds; Biguanides; Chlorhexidine; Microbial Sensitivity Tests; Triclosan | 2015 |
Riboflavin and ultraviolet A as adjuvant treatment against Acanthamoeba cysts.
Topics: Acanthamoeba; Biguanides; Chlorhexidine; Disinfectants; Drug Synergism; Humans; Parasitic Sensitivity Tests; Photochemotherapy; Photosensitizing Agents; Riboflavin; Ultraviolet Rays | 2016 |
Antimicrobial functionalization of bacterial nanocellulose by loading with polihexanide and povidone-iodine.
Topics: Acetobacteraceae; Anti-Infective Agents, Local; Bandages; Biguanides; Biocompatible Materials; Biomechanical Phenomena; Cell Line; Cellulose; Humans; Materials Testing; Nanoparticles; Povidone-Iodine; Staphylococcus aureus | 2015 |
Potential Value of Cellulose Synthesis Inhibitors Combined With PHMB in the Treatment of Acanthamoeba Keratitis.
Topics: Acanthamoeba castellanii; Acanthamoeba Keratitis; Amebicides; Animals; Benzamides; Biguanides; Cells, Cultured; Disinfectants; Drug Combinations; Epithelium, Corneal; Eye Infections, Parasitic; Glucosyltransferases; Humans; Nitriles; Parasite Encystment | 2015 |
Pathogen- and Host-Directed Antileishmanial Effects Mediated by Polyhexanide (PHMB).
Topics: Animals; Biguanides; Cells, Cultured; Female; Leishmania major; Mice; Mice, Inbred BALB C; Oligodeoxyribonucleotides | 2015 |
Photodynamic Inactivation of Actinomyces naeslundii in Comparison With Chlorhexidine and Polyhexanide--A New Approach for Antiseptic Treatment of Medication-Related Osteonecrosis of the Jaw?
Topics: Actinomyces; Anti-Infective Agents, Local; Bacterial Load; Biguanides; Bisphosphonate-Associated Osteonecrosis of the Jaw; Chlorhexidine; Fluorescent Dyes; Humans; Lasers, Semiconductor; Methylene Blue; Microbial Viability; Photochemotherapy; Photosensitizing Agents | 2016 |
Opinion of the scientific committee on consumer safety (SCCS)--2nd Revision of the safety of the use of poly(hexamethylene) biguanide hydrochloride or polyaminopropyl biguanide (PHMB) in cosmetic products.
Topics: Administration, Cutaneous; Animals; Biguanides; Consumer Product Safety; Cosmetics; Humans; Risk Assessment; Risk Factors | 2015 |
Contact Lens Corneal Inflammatory Events in a University Population.
Topics: Adolescent; Adult; Age Factors; Biguanides; Contact Lenses, Hydrophilic; Cross-Sectional Studies; Disinfectants; Disposable Equipment; Female; Humans; Keratitis; Male; Odds Ratio; Polymers; Propylamines; Prospective Studies; Risk Factors; Universities; Young Adult | 2016 |
Polyhexamethylene biguanide in wound care products: a non-negligible cause of peri-ulcer dermatitis.
Topics: Biguanides; Dermatitis, Allergic Contact; Disinfectants; Female; Humans; Leg Ulcer; Middle Aged | 2016 |
Characterizing clinical isolates of Acanthamoeba castellanii with high resistance to polyhexamethylene biguanide in Taiwan.
Topics: Acanthamoeba castellanii; Amebiasis; Biguanides; Cornea; Drug Resistance; Drug Tolerance; Gene Expression; Humans; Microscopy; Parasitic Sensitivity Tests; Real-Time Polymerase Chain Reaction; RNA, Protozoan; RNA, Ribosomal, 18S; Taiwan; Time Factors | 2017 |
The safety and efficacy of bacterial nanocellulose wound dressing incorporating sericin and polyhexamethylene biguanide: in vitro, in vivo and clinical studies.
Topics: Adolescent; Adult; Aged; Animals; Bandages, Hydrocolloid; Biguanides; Cell Line; Cell Movement; Cellulose; Female; Humans; Inflammation; L Cells; Male; Mice; Middle Aged; Prospective Studies; Rats; Sericins; Skin; Wound Healing; Young Adult | 2016 |
Bactericidal effects of polyhexamethylene biguanide against intracellular Staphylococcus aureus EMRSA-15 and USA 300.
Topics: Anti-Bacterial Agents; Biguanides; Cell Line; Fluoroquinolones; Humans; Keratinocytes; Microbial Sensitivity Tests; Microbial Viability; Quinolizines; Staphylococcus aureus | 2016 |
A novel approach to antibiofilm susceptibility testing using a thermo-reversible matrix.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Biguanides; Biofilms; Carbonates; Humans; Imines; Microbial Sensitivity Tests; Povidone-Iodine; Pseudomonas aeruginosa; Pyridines; Silver Compounds | 2016 |
Case 14: Octenilin Wound Gel versus betadine/PHMB gel.
Topics: Adult; Anti-Infective Agents, Local; Biguanides; Diabetes Mellitus, Type 2; Diabetic Foot; Disinfectants; Humans; Imines; Male; Povidone-Iodine; Pyridines; Treatment Outcome; Wound Healing | 2016 |
Versatile synthesis of PHMB-stabilized silver nanoparticles and their significant stimulating effect on fodder beet (Beta vulgaris L.).
Topics: Beta vulgaris; Biguanides; Germination; Indoleacetic Acids; Metal Nanoparticles; Microscopy, Electron, Scanning; Oxidoreductases; Particle Size; Plant Proteins; Seeds; Silver; Silver Nitrate; X-Ray Diffraction | 2016 |
The antimicrobial polymer PHMB enters cells and selectively condenses bacterial chromosomes.
Topics: Animals; Anti-Bacterial Agents; Bacillus megaterium; Biguanides; Cattle; Cell Membrane Permeability; CHO Cells; Chromosome Structures; Chromosomes, Bacterial; Cricetinae; Cricetulus; Escherichia coli; HEK293 Cells; HeLa Cells; Horses; Humans; Mice; Microbial Sensitivity Tests; Mycobacterium smegmatis; Salmonella typhimurium; Stress, Physiological | 2016 |
In vitro activity of a polyhexanide-betaine solution against high-risk clones of multidrug-resistant nosocomial pathogens.
Topics: Bacteria; Betaine; Biguanides; Cross Infection; Disinfectants; Microbial Sensitivity Tests; Solutions | 2017 |
[Influence of Chlorhexidine and Prontosan on Dual Species and Monospecies Biofilms Formed by Staphylococcus aureus and Pseudomonas aeruginosa].
Topics: Anti-Infective Agents, Local; Betaine; Biguanides; Biofilms; Chlorhexidine; Microscopy, Atomic Force; Pseudomonas aeruginosa; Staphylococcus aureus | 2015 |
NCW2, a Gene Involved in the Tolerance to Polyhexamethylene Biguanide (PHMB), May Help in the Organisation of β-1,3-Glucan Structure of Saccharomyces cerevisiae Cell Wall.
Topics: Antifungal Agents; beta-Glucans; Biguanides; Cell Wall; Drug Resistance, Fungal; Gene Expression Regulation, Fungal; Membrane Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2016 |
Comparing two polymeric biguanides: chemical distinction, antiseptic efficacy and cytotoxicity of polyaminopropyl biguanide and polyhexamethylene biguanide.
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Cell Line; Cell Survival; Escherichia coli; Fibroblasts; Humans; Keratinocytes; Mass Spectrometry; Mice; Microbial Viability; Pseudomonas aeruginosa; Staphylococcus aureus | 2016 |
Biobrane versus topical agents in the treatment of adult scald burns.
Topics: Administration, Cutaneous; Adult; Age Factors; Aged; Alcohol Drinking; Biguanides; Body Surface Area; Burns; Coated Materials, Biocompatible; Comorbidity; Diabetes Mellitus; Disinfectants; Female; Humans; Hypertension; Length of Stay; Male; Middle Aged; Occlusive Dressings; Retrospective Studies; Smoking; Trauma Severity Indices; Wound Infection | 2017 |
[POLYHEXAMETHYLENE BIGUANID HYDROCHLORIDE (BIGUANELLE) THERAPY OF BACTERIAL VAGINOSIS].
Topics: Administration, Intravaginal; Adolescent; Adult; Anti-Infective Agents, Local; Biguanides; Female; Humans; Middle Aged; Vagina; Vaginosis, Bacterial; Young Adult | 2016 |
Effectiveness of polyhexamethylene biguanide impregnated dressing in wound healing: a systematic review protocol.
Topics: Anti-Bacterial Agents; Bandages; Biguanides; Humans; Systematic Reviews as Topic; Wound Healing | 2016 |
Evaluation of Protamine as a Disinfectant for Contact Lenses.
Topics: Anti-Infective Agents; Bacteria; Biguanides; Colony Count, Microbial; Contact Lens Solutions; Contact Lenses; Disinfectants; Disinfection; Drug Combinations; Fungi; Heparin Antagonists; Humans; Protamines | 2016 |
[Good outcome in Acanthamoeba keratitis].
Topics: Acanthamoeba Keratitis; Adult; Antiprotozoal Agents; Benzamidines; Biguanides; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Pregnancy; Pregnancy Complications; Treatment Outcome | 2017 |
In Vitro activity of Manuka Honey and polyhexamethylene biguanide on filamentous fungi and toxicity to human cell lines.
Topics: Biguanides; Cell Line; Cell Survival; Disinfectants; Fibroblasts; Fungi; Honey; Humans; Keratinocytes; Lethal Dose 50; Microbial Sensitivity Tests; Osteoblasts; Time Factors | 2017 |
Negative Pressure Wound Therapy With Instillation and Dwell Time Used to Treat Infected Orthopedic Implants: A 4-patient Case Series.
Topics: Aged; Anti-Bacterial Agents; Biguanides; Female; Humans; Internal Fixators; Male; Middle Aged; Negative-Pressure Wound Therapy; Orthopedic Procedures; Surgical Wound Infection; Therapeutic Irrigation; Wound Healing | 2016 |
In vitro inflammatory effects of polyhexamethylene biguanide through NF-κB activation in A549 cells.
Topics: A549 Cells; Biguanides; Cell Survival; Disinfectants; Inflammation; Interleukin-6; NF-kappa B; Reactive Oxygen Species; Tumor Necrosis Factor-alpha | 2017 |
0.1% Polyhexanide-Betaine Solution as an Adjuvant in a Case-Series of Chronic Wounds.
Topics: Betaine; Biguanides; Chronic Disease; Disinfectants; Humans; Prospective Studies; Retrospective Studies; Skin Diseases | 2016 |
Cytocompatibility testing of cyclodextrin-functionalized antimicrobial textiles-a comprehensive approach.
Topics: Anti-Infective Agents; Anti-Infective Agents, Local; Apoptosis; Bacterial Infections; Biguanides; Biocompatible Materials; Candida albicans; Caspase 3; Cell Line; Cell Survival; Cyclodextrins; Escherichia coli; Flow Cytometry; Humans; Keratinocytes; Klebsiella pneumoniae; Materials Testing; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis; Textiles | 2016 |
Painless Acanthamoeba Keratitis with Normal Vision.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Antiprotozoal Agents; Benzamidines; Biguanides; Contact Lenses, Hydrophilic; Cornea; Disinfectants; Drug Therapy, Combination; Eye Pain; Female; Humans; Visual Acuity | 2017 |
The effect of the disulfideisomerase domain containing protein in the defense against polyhexamethylene biguanide of highly tolerant Acanthamoeba at the trophozoite stage.
Topics: Acanthamoeba castellanii; Biguanides; Disinfectants; Drug Tolerance; Gene Expression Profiling; Gene Silencing; Protein Disulfide-Isomerases; Protozoan Proteins; RNA, Messenger; Trophozoites | 2016 |
Antimicrobial activity of different disinfectants against cariogenic microorganisms.
Topics: Agar; Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Dental Caries; Gram-Positive Bacteria; Imines; Microbial Sensitivity Tests; Pyridines; Reproducibility of Results; Spectrophotometry; Time Factors | 2016 |
Proposed phase 2/ step 2 in-vitro test on basis of EN 14561 for standardised testing of the wound antiseptics PVP-iodine, chlorhexidine digluconate, polihexanide and octenidine dihydrochloride.
Topics: Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Enterococcus faecium; Humans; Imines; In Vitro Techniques; Microbial Sensitivity Tests; Microbial Viability; Povidone-Iodine; Pseudomonas aeruginosa; Pyridines; Staphylococcus aureus; Time Factors | 2017 |
Cytotoxicity and molecular effects of biocidal disinfectants (quaternary ammonia, glutaraldehyde, poly(hexamethylene biguanide) hydrochloride PHMB) and their mixtures in vitro and in zebrafish eleuthero-embryos.
Topics: Ammonia; Animals; Biguanides; Cell Line; Disinfectants; Embryo, Nonmammalian; Glutaral; Humans; Toxicity Tests; Zebrafish | 2017 |
The benefits of using polyhexamethylene biguanide in wound care.
Topics: Bandages; Biguanides; Biofilms; Disinfectants; Humans; Wound Infection; Wounds and Injuries | 2017 |
Effectiveness of a polyhexanide irrigation solution on methicillin-resistant Staphylococcus aureus biofilms in a porcine wound model.
Topics: Animals; Betaine; Biguanides; Biofilms; Disease Models, Animal; Disinfectants; Methicillin-Resistant Staphylococcus aureus; Staphylococcal Infections; Swine; Wounds and Injuries | 2017 |
Antibacterial activity of polihexanide formulations in a co-culture of HaCaT keratinocytes and Staphylococcus aureus and at different pH levels.
Topics: Anti-Bacterial Agents; Bandages; Biguanides; Coculture Techniques; Humans; Hydrogen-Ion Concentration; Keratinocytes; Microbial Viability; Staphylococcus aureus; Wound Infection; Wounds and Injuries | 2017 |
Albumin reduces the antibacterial efficacy of wound antiseptics against Staphylococcus aureus.
Topics: Anti-Infective Agents, Local; Biguanides; Ethylene Glycols; Exudates and Transudates; Humans; Imines; Microbial Sensitivity Tests; Povidone-Iodine; Pyridines; Serum Albumin, Bovine; Staphylococcal Infections; Staphylococcus aureus; Wound Infection | 2017 |
A study of long-term stability and antimicrobial activity of chlorhexidine, polyhexamethylene biguanide, and silver nanoparticle incorporated in sericin-based wound dressing.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bandages; Biguanides; Chlorhexidine; Drug Carriers; Drug Stability; Male; Metal Nanoparticles; Rats; Rats, Sprague-Dawley; Safety; Sericins; Silver; Wound Healing | 2017 |
Free-Living Amoebae Keratitis.
Topics: Acanthamoeba; Amebiasis; Amoeba; Animals; Biguanides; Cornea; Disinfectants; DNA Primers; DNA, Protozoan; DNA, Ribosomal; Eye Infections, Parasitic; Female; Hartmannella; Humans; Keratitis; Male; Ophthalmic Solutions; Polymerase Chain Reaction; Prospective Studies; RNA, Ribosomal, 18S | 2017 |
Allergic contact dermatitis caused by poly(hexamethylene) biguanide hydrochloride in contact lens care solutions.
Topics: Biguanides; Contact Lens Solutions; Dermatitis, Allergic Contact; Female; Hand Dermatoses; Humans; Middle Aged | 2017 |
Preparation of nano cationic liposome as carrier membrane for polyhexamethylene biguanide chloride through various methods utilizing higher antibacterial activities with low cell toxicity.
Topics: Anti-Bacterial Agents; Biguanides; Cell Line; Escherichia coli; Fibroblasts; Humans; Liposomes; Nanoparticles; Staphylococcus aureus | 2017 |
Wound-bed preparation: a vital step in the healing process.
Topics: Administration, Cutaneous; Anti-Bacterial Agents; Anti-Infective Agents, Local; Biguanides; Biofilms; Debridement; Disinfectants; Drug Resistance, Bacterial; Humans; Wound Healing; Wound Infection; Wounds and Injuries | 2017 |
In-vitro release pharmacokinetics of amikacin, teicoplanin and polyhexanide in a platelet rich fibrin-layer (PRF)-a laboratory evaluation of a modern, autologous wound treatment.
Topics: Agar; Amikacin; Anti-Bacterial Agents; Bandages; Biguanides; Delayed-Action Preparations; Disk Diffusion Antimicrobial Tests; Drug Liberation; Fibrin; Humans; Klebsiella pneumoniae; Methicillin-Resistant Staphylococcus aureus; Models, Biological; Platelet-Derived Growth Factor; Platelet-Rich Plasma; Pseudomonas aeruginosa; Teicoplanin; Wound Healing | 2017 |
Effect of poly-hexamethylene biguanide hydrochloride (PHMB) treated non-sterile medical gloves upon the transmission of Streptococcus pyogenes, carbapenem-resistant E. coli, MRSA and Klebsiella pneumoniae from contact surfaces.
Topics: Biguanides; Carbapenems; Cross Infection; Disease Transmission, Infectious; Disinfectants; Drug Resistance, Bacterial; Escherichia coli; Gloves, Protective; Humans; Infection Control; Klebsiella pneumoniae; Methicillin-Resistant Staphylococcus aureus; Streptococcus pyogenes | 2017 |
A Case of Severe Anaphylaxis to Polyhexanide: Cross-Reactivity between Biguanide Antiseptics.
Topics: Aged; Allergens; Anaphylaxis; Anti-Infective Agents, Local; Biguanides; Cross Reactions; Disinfectants; Drug Hypersensitivity; Female; Humans; Immunoglobulin E; Skin Tests | 2017 |
Ephemeral biogels to control anti-biofilm agent delivery: From conception to the construction of an active dressing.
Topics: Anti-Bacterial Agents; Bandages; Biguanides; Biofilms; Edetic Acid; Gelatin; Gels; Pseudomonas aeruginosa; Rheology; Staphylococcus aureus | 2018 |
Enhanced killing of Escherichia coli using a combination of polyhexamethylene biguanide hydrochloride and 1-bromo-3-chloro-5,5- dimethylimidazolidine-2,4-dione.
Topics: Anti-Bacterial Agents; Biguanides; Cell Membrane; Cell Membrane Permeability; Escherichia coli; Hydantoins; Magnesium; Potassium | 2017 |
Study of the Effectiveness of Multipurpose Solutions on the Bacterial Disinfection of Silicone Hydrogel Contact Lenses In Vitro.
Topics: Anti-Infective Agents; Biguanides; Contact Lens Solutions; Contact Lenses, Hydrophilic; Disinfection; Eye Infections, Bacterial; Humans; Hydrogels; Propylamines; Pseudomonas aeruginosa; Silicone Elastomers; Staphylococcus aureus; Staphylococcus epidermidis | 2018 |
Polyhexamethylene biguanide and alkyl glucosides: unexpected allergens in an antimicrobial foam dressing.
Topics: Adolescent; Bandages; Biguanides; Dermatitis, Allergic Contact; Glucosides; Humans; Male; Patch Tests; Preservatives, Pharmaceutical; Surface-Active Agents | 2017 |
Effect of polyhexamethylene biguanide on rat liver.
Topics: Administration, Oral; Animals; Biguanides; Cell Proliferation; Disinfectants; Dose-Response Relationship, Drug; Female; Hepatocytes; Liver; Liver Function Tests; Male; Oxidative Stress; Rats, Wistar; Toxicity Tests | 2018 |
Acanthamoeba keratitis in Porto Alegre (southern Brazil): 28 cases and risk factors.
Topics: Acanthamoeba Keratitis; Adult; Benzamidines; Biguanides; Brazil; Chlorhexidine; Contact Lens Solutions; Contact Lenses; Female; Humans; Male; Retrospective Studies; Risk Factors; Treatment Outcome | 2018 |
Amebaborne "Attilina massiliensis" Keratitis, France.
Topics: Acanthamoeba castellanii; Acanthamoeba Keratitis; Adolescent; Alphaproteobacteria; Benzamidines; Biguanides; Corynebacterium; Corynebacterium Infections; Female; Humans; Keratitis | 2018 |
Autolytic debridement and management of bacterial load with an occlusive hydroactive deressing impregnated with polyhexamethylene biguanide.
Topics: Aged; Aged, 80 and over; Bacterial Load; Biguanides; Debridement; Disinfectants; Humans; Leg Ulcer; Occlusive Dressings | 2018 |
Effect of a New Purified Collagen Matrix With Polyhexamethylene Biguanide on Recalcitrant Wounds of Various Etiologies: A Case Series.
Topics: Aged; Anti-Infective Agents, Local; Biguanides; Calciphylaxis; Chronic Disease; Collagen Type I; Diabetic Foot; Female; Humans; Male; Middle Aged; Pressure Ulcer; Skin Ulcer; Surgical Wound Dehiscence; Varicose Ulcer; Wound Healing | 2018 |
Keratomycosis due to Tintelnotia destructans refractory to common therapy treated successfully with systemic and local terbinafine in combination with polyhexamethylene biguanide.
Topics: Adult; Antifungal Agents; Ascomycota; Biguanides; Disinfectants; Humans; Keratitis; Terbinafine | 2019 |
[Comparison of the antibacterial efficacy of polyhexanide, cold atmospheric argon plasma and saline in the treatment of canine bite wounds].
Topics: Animals; Anti-Bacterial Agents; Argon; Biguanides; Bites and Stings; Dog Diseases; Dogs; Plasma Gases; Sodium Chloride; Wound Healing; Wound Infection | 2018 |
Hexavalent chromium removal from aqueous solution using functionalized chitosan as a novel nano-adsorbent: modeling and optimization, kinetic, isotherm, and thermodynamic studies, and toxicity testing.
Topics: Adsorption; Animals; Biguanides; Chitosan; Chromium; Daphnia; Drinking Water; Kinetics; Models, Theoretical; Nanoparticles; Thermodynamics; Toxicity Tests; Water Pollutants, Chemical; Water Purification | 2018 |
Decolonization potential of 0.02% polyhexanide irrigation solution in urethral catheters under practice-like in vitro conditions.
Topics: Bacterial Load; Biguanides; Catheter-Related Infections; Catheters, Indwelling; Colony Count, Microbial; Disinfectants; Drug Compounding; Humans; Pharmaceutical Solutions; Staphylococcus aureus; Urinary Catheterization; Urinary Tract Infections | 2018 |
Polyhexamethylene biguanide and chloroquine induce programmed cell death in Acanthamoeba castellanii.
Topics: Acanthamoeba castellanii; Acanthamoeba Keratitis; Amebicides; Biguanides; Cell Nucleus; Cells, Cultured; Chlorhexidine; Chloroquine; Culture Media; DNA Fragmentation; Epithelium, Corneal; Humans; Nitriles; Phosphatidylserines | 2018 |
Inhibition of Bromelain Activity During Enzymatic Debridement of Burn Wounds Pretreated With Frequently Used Products.
Topics: Anti-Infective Agents, Local; Betaine; Biguanides; Bromelains; Burns; Collagen; Debridement; Elastin; Ethanolamines; Imines; Pyridines; Skin, Artificial; Undecylenic Acids | 2018 |
Antimicrobial effectiveness of polyhexamethylene biguanide on Enterococcus faecalis, Staphylococcus epidermidis and Candida albicans.
Topics: Anti-Bacterial Agents; Antifungal Agents; Biguanides; Candida albicans; Chlorhexidine; Dental Pulp Cavity; Enterococcus faecalis; Humans; Microbial Sensitivity Tests; Sodium Hypochlorite; Staphylococcus epidermidis | 2018 |
Cleansing versus tailored deep debridement, a fresh approach to wound cleansing: an Italian experience.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Bandages; Betaine; Biguanides; Debridement; Female; Humans; Male; Middle Aged; Skin Ulcer; Surface-Active Agents; Time Factors; Wound Healing | 2018 |
Contact lens-related polymicrobial keratitis: Acanthamoeba spp. genotype T4 and Candida albicans.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Biguanides; Candida albicans; Candidiasis; Chlorhexidine; Contact Lenses; Cornea; DNA, Ribosomal; Female; Genotype; Humans; RNA, Ribosomal, 18S | 2018 |
A retrospective systematic data review on the use of a polihexanide-containing product on burns in children.
Topics: Adolescent; Bandages; Biguanides; Burns; Child; Child, Preschool; Disinfectants; Female; Humans; Infant; Infant, Newborn; Male; Pediatrics; Retrospective Studies; Wound Healing | 2018 |
Efficiency of Emulsified Particle-Associated Polyhexamethylenbiguanid-Hydrochlorid (Polihexanide) for Peritoneal Lavage in a Murine Sepsis Model.
Topics: Animals; Bacterial Load; Biguanides; Cytokines; Disease Models, Animal; Disinfectants; Female; Mice; Mice, Inbred C57BL; Peritoneal Lavage; Peritonitis; Sepsis | 2018 |
Intracorneal injection of a detachable hybrid microneedle for sustained drug delivery.
Topics: Acanthamoeba Keratitis; Animals; Biguanides; Cornea; Dimethylpolysiloxanes; Drug Delivery Systems; Female; Mice, Inbred C57BL; Microinjections; Needles; Polylactic Acid-Polyglycolic Acid Copolymer; Pressure | 2018 |
Influence of the incorporation of the antimicrobial agent polyhexamethylene biguanide on the properties of dense and porous chitosan-alginate membranes.
Topics: Alginates; Anti-Infective Agents; Biguanides; Chitosan; Membranes, Artificial; Porosity; Pseudomonas aeruginosa; Staphylococcus aureus | 2018 |
Comparison of the bactericidal effect of cold atmospheric pressure plasma (CAPP), antimicrobial photodynamic therapy (aPDT), and polihexanide (PHX) in a novel wet surface model to mimic oral cavity application.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Atmospheric Pressure; Biguanides; Biofilms; Disinfectants; In Vitro Techniques; Microbial Viability; Photochemotherapy; Plasma Gases; Staphylococcus aureus; Stem Cells; Surface Properties | 2018 |
Water-Insoluble Polymeric Guanidine Derivative and Application in the Preparation of Antibacterial Coating of Catheter.
Topics: Animals; Anti-Bacterial Agents; Biguanides; Biofilms; Catheter-Related Infections; Catheters; Cell Line; Coated Materials, Biocompatible; Erythrocytes; Escherichia coli; Female; Fibroblasts; Mice; Mice, Inbred BALB C; Rabbits; Solubility; Staphylococcus aureus; Stearic Acids; Water | 2018 |
Molluscicidal activity of polyhexamethylene biguanide hydrochloride on the early-life stages and adults of the Biomphalaria glabrata (Say, 1818).
Topics: Animals; Biguanides; Biomphalaria; Molluscacides; Schistosoma mansoni | 2019 |
Uptake of PHMB in a bacterial nanocellulose-based wound dressing: A feasible clinical procedure.
Topics: Bandages; Biguanides; Cellulose; Disinfectants; Humans; Microbial Sensitivity Tests; Spectrophotometry; Staphylococcus aureus; Wound Infection | 2019 |
Biocide Exposure Induces Changes in Susceptibility, Pathogenicity, and Biofilm Formation in Uropathogenic
Topics: Animals; Anti-Bacterial Agents; Benzalkonium Compounds; Biguanides; Biofilms; Catheter-Related Infections; Cell Line; Ciprofloxacin; Disinfectants; Drug Resistance, Bacterial; Escherichia coli Infections; Gentamicins; L Cells; Mice; Microbial Sensitivity Tests; Moths; Nitrofurantoin; Silver Nitrate; Triclosan; Trimethoprim, Sulfamethoxazole Drug Combination; Uropathogenic Escherichia coli; Virulence | 2019 |
Effect of polyhexamethylene biguanide functionalized silver nanoparticles on the growth of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Biguanides; Cell Wall; Metal Nanoparticles; Microbial Sensitivity Tests; Silver; Staphylococcus aureus | 2019 |
Re-evaluation of polihexanide use in wound antisepsis in order to clarify ambiguities of two animal studies.
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Consensus; Disease Models, Animal; Risk Assessment; Surgical Wound Infection; Wound Healing | 2019 |
Comparative activity of a polyhexanide-betaine solution against biofilms produced by multidrug-resistant bacteria belonging to high-risk clones.
Topics: Betaine; Biguanides; Biofilms; Chlorhexidine; Disinfectants; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Microbial Viability; Solutions | 2019 |
Analysis from a year of increased cases of Acanthamoeba Keratitis in a large teaching hospital in the UK.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adult; Anti-Infective Agents, Local; Antiprotozoal Agents; Benzamidines; Biguanides; Chlorhexidine; Contact Lenses; Disinfectants; DNA, Protozoan; Female; Hospitals, Teaching; Humans; Incidence; Male; Middle Aged; Polymerase Chain Reaction; Retrospective Studies; Risk Factors; United Kingdom; Visual Acuity; Young Adult | 2019 |
Determination of Polyhexamethylene Biguanide Utilizing a Glucose Oxidase Enzymatic Reaction.
Topics: Aspergillus niger; Biguanides; Biosensing Techniques; Ferricyanides; Glucose Oxidase; Limit of Detection; Osmolar Concentration | 2019 |
Guanidine-based disinfectants, polyhexamethylene guanidine-phosphate (PHMG-P), polyhexamethylene biguanide (PHMB), and oligo(2-(2-ethoxy)ethoxyethyl guanidinium chloride (PGH) induced epithelial-mesenchymal transition in A549 alveolar epithelial cells.
Topics: A549 Cells; Actins; Alveolar Epithelial Cells; Antigens, CD; Biguanides; Cadherins; Cell Membrane; Cell Survival; Disinfectants; Epithelial-Mesenchymal Transition; Guanidines; Humans; L-Lactate Dehydrogenase; Polymers; Toxicity Tests | 2019 |
A biodegradable poly(amido amine) based on the antimicrobial polymer polyhexamethylene biguanide for efficient and safe gene delivery.
Topics: Acrylamides; Animals; Anti-Infective Agents; Biguanides; Cell Line, Tumor; Deoxyribonuclease I; Diamines; Dithiothreitol; Endocytosis; Gene Transfer Techniques; Genes, Reporter; Heparin; Hexanes; Humans; Hydrolysis; Luciferases; Mice; Neuroglia; NIH 3T3 Cells; Plasmids; Polyethyleneimine | 2019 |
Highly transparent, highly flexible composite membrane with multiple antimicrobial effects used for promoting wound healing.
Topics: Animals; Anti-Bacterial Agents; Bandages; Biguanides; Biocompatible Materials; Cellulose; Escherichia coli; Human Umbilical Vein Endothelial Cells; Humans; Mice; Polyethylene Glycols; Skin; Staphylococcus aureus; Wound Healing | 2019 |
[Morphological justification of the effectiveness of ultrasonic cavitation with 0.2].
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Biguanides; Diabetes Mellitus, Type 2; Diabetic Foot; Humans; Middle Aged; Necrosis; Solutions; Ultrasonic Surgical Procedures | 2019 |
Susceptibility of livestock-associated methicillin-resistant
Topics: Animals; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Community-Acquired Infections; Cross Infection; Humans; Imines; Livestock; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microbial Viability; Povidone-Iodine; Pyridines; Staphylococcal Infections; Triclosan | 2019 |
The Anti-Fibrotic Effects of CG-745, an HDAC Inhibitor, in Bleomycin and PHMG-Induced Mouse Models.
Topics: Animals; Biguanides; Bleomycin; Disease Models, Animal; Epithelial-Mesenchymal Transition; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Idiopathic Pulmonary Fibrosis; Indoles; Lung; Mice; Pyridones; Republic of Korea | 2019 |
Topics: Acanthamoeba Keratitis; Adolescent; Adult; Aged; Antiprotozoal Agents; Biguanides; Chlorhexidine; Disinfectants; Drug Therapy, Combination; Female; Humans; Male; Microscopy, Confocal; Middle Aged; Pentamidine; Retrospective Studies; Visual Acuity; Young Adult | 2020 |
Evaluation of prevention and disruption of biofilm in contact lens cases.
Topics: Biguanides; Biofilms; Chlorhexidine; Contact Lens Solutions; Contact Lenses, Hydrophilic; Disinfectants; Humans; Povidone-Iodine; Pseudomonas aeruginosa; Staphylococcus aureus | 2019 |
Analysis of polyhexamethylene biguanide and alexidine in contact lens solutions using capillary electrophoresis, ultra-performance liquid chromatography and quadrupole time of flight mass spectrometry.
Topics: Biguanides; Chromatography, Liquid; Chromatography, Reverse-Phase; Contact Lens Solutions; Disinfectants; Electrophoresis, Capillary; Mass Spectrometry; Reproducibility of Results; Solid Phase Extraction | 2019 |
Treating drug-resistant wound pathogens with non-medicated dressings: an
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biguanides; Biofilms; Culture Techniques; Methicillin-Resistant Staphylococcus aureus; Pseudomonas aeruginosa; Wound Infection | 2019 |
Acanthamoeba keratitis related to contact lens use in a tertiary hospital in China.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Adult; Anti-Infective Agents, Local; Biguanides; Child; China; Chlorhexidine; Contact Lenses; Corneal Ulcer; Disinfectants; DNA, Protozoan; Drug Combinations; Eye Infections, Parasitic; Female; Humans; Keratoplasty, Penetrating; Male; Microscopy, Confocal; Middle Aged; Polymerase Chain Reaction; Retrospective Studies; RNA, Ribosomal, 18S; Tertiary Care Centers; Young Adult | 2019 |
The effects of the Ncw2 protein of Saccharomyces cerevisiae on the positioning of chitin in response to cell wall damage.
Topics: Biguanides; Cell Wall; Chitin; Gene Expression Regulation, Fungal; Membrane Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins | 2020 |
A novel zinc oxide eugenol modified by polyhexamethylene biguanide: Physical and antimicrobial properties.
Topics: Anti-Infective Agents; Biguanides; Eugenol; Root Canal Filling Materials; Zinc Oxide; Zinc Oxide-Eugenol Cement | 2020 |
Use of a monofilament debridement pad in the treatment of acne vulgaris.
Topics: Acne Vulgaris; Adolescent; Biguanides; Debridement; Equipment Design; Face; Female; Humans; Male; Severity of Illness Index; Sodium Hypochlorite; Young Adult | 2019 |
Histone Deacetylase Inhibitors Enhance the Amoebicidal Effect of Low Concentration of Polyhexamethylene Biguanide by Inducing Apoptosis.
Topics: Acanthamoeba castellanii; Annexin A5; Apoptosis; Benzamides; Biguanides; Cells, Cultured; Disinfectants; Drug Synergism; Epithelium, Corneal; Flow Cytometry; Fluorescein-5-isothiocyanate; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Pyridines; Pyrroles; Vorinostat | 2020 |
Poly (hexamethylene biguanide), adsorbed onto Ti-Al-V alloys, kills slime-producing Staphylococci and Pseudomonas aeruginosa without inhibiting SaOs-2 cell differentiation.
Topics: Alkaline Phosphatase; Alloys; Anti-Bacterial Agents; Biguanides; Cell Adhesion; Cell Differentiation; Cell Line; Cell Proliferation; Coated Materials, Biocompatible; Humans; Osteoblasts; Prostheses and Implants; Pseudomonas aeruginosa; Staphylococcus; Surface Properties; Titanium | 2020 |
Determination of Polyhexamethylene Biguanide Hydrochloride Using a Lactone-Rhodamine B-Based Fluorescence Optode.
Topics: Biguanides; Fluorescence; Lactones; Rhodamines | 2020 |
In vitro evaluation of contact-active antibacterial efficacy of Ti-Al-V alloys coated with the antimicrobial agent PHMB.
Topics: Alloys; Anti-Bacterial Agents; Biguanides; Biofilms; Coated Materials, Biocompatible; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Staphylococcus epidermidis; Titanium | 2020 |
The Antimicrobial Activity of Multipurpose Disinfecting Solutions in the Presence of Different Organic Soils.
Topics: Bacteria; Biguanides; Colony Count, Microbial; Contact Lens Solutions; Disinfection; Fungi; Hydrogen Peroxide; Microbial Sensitivity Tests; Polymers; Povidone-Iodine; Tears | 2020 |
Influence of human wound exudate on the bactericidal efficacy of antiseptic agents in quantitative suspension tests on the basis of European Standards (DIN EN 13727).
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Biguanides; Chlorhexidine; Exudates and Transudates; Female; Humans; Imines; Leg Ulcer; Male; Microbial Sensitivity Tests; Middle Aged; Povidone-Iodine; Pyridines; Tissue Culture Techniques | 2020 |
A multimodel regime for evaluating effectiveness of antimicrobial wound care products in microbial biofilms.
Topics: Acinetobacter baumannii; Administration, Topical; Animals; Anti-Infective Agents, Local; Benzalkonium Compounds; Biguanides; Biofilms; Candida; Candida albicans; Coinfection; Enterobacter cloacae; Enterococcus faecalis; Hypochlorous Acid; Imines; In Vitro Techniques; Iodine; Klebsiella pneumoniae; Mice; Poloxamer; Pseudomonas aeruginosa; Pyridines; Silver; Staphylococcus aureus; Streptococcus pyogenes; Sus scrofa; Wound Infection | 2020 |
Efficacy of antiseptics in a novel 3-dimensional human plasma biofilm model (hpBIOM).
Topics: Anti-Infective Agents, Local; Biguanides; Biofilms; Drug Resistance, Bacterial; Glycocalyx; Humans; Imines; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Plasma; Pseudomonas aeruginosa; Pyridines; Time Factors; Translational Research, Biomedical | 2020 |
Polyvinyl Alcohol/Chitosan/Polyhexamethylene Biguanide Phase Separation System: A Potential Topical Antibacterial Formulation with Enhanced Antimicrobial Effect.
Topics: Animals; Anti-Bacterial Agents; Biguanides; Chitosan; Escherichia coli; Mice; Mice, Nude; Microbial Sensitivity Tests; Polyvinyl Alcohol; Staphylococcus aureus; Water; Wound Healing | 2020 |
Antibacterial efficacy of chitosan- and poly(hexamethylene biguanide)-immobilized nanofiber membrane.
Topics: Anti-Bacterial Agents; Biguanides; Chitosan; Escherichia coli; Membranes, Artificial; Nanofibers; Water Purification | 2020 |
An Original Use of a Bioluminescence Assay to Test the In Vitro Efficacy of Polihexanide in the Eradication of Acanthamoeba Cysts.
Topics: Acanthamoeba; Animals; Biguanides; Cornea; Disinfectants; Eye Infections, Parasitic; Humans | 2020 |
Development of a PHMB hydrogel-modified wound scaffold dressing with antibacterial activity.
Topics: Acinetobacter baumannii; Animals; Anti-Infective Agents, Local; Bandages; Biguanides; Disinfectants; Endothelial Cells; Fibroblasts; Guinea Pigs; Humans; Hydrogels; Klebsiella pneumoniae; Rabbits; Rats; Skin; Skin, Artificial; Staphylococcus aureus; Wound Infection; Wounds and Injuries | 2020 |
Micropore Particle Technology Promotes Wound Healing, Whereas Polyhexamethylene Biguanide Causes Tissue Degeneration: A Case Report.
Topics: Abscess; Aged; Anti-Infective Agents, Local; Biguanides; Biomedical Technology; Debridement; Exudates and Transudates; Female; Humans; Osteomyelitis; Powders; Pressure Ulcer; Spinal Cord Injuries; Wound Healing; Wound Infection | 2020 |
Insights into the Polyhexamethylene Biguanide (PHMB) Mechanism of Action on Bacterial Membrane and DNA: A Molecular Dynamics Study.
Topics: Anti-Infective Agents; Biguanides; DNA; Molecular Dynamics Simulation | 2020 |
Type I collagen matrix plus polyhexamethylene biguanide antimicrobial for the treatment of cutaneous wounds.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Biguanides; Cohort Studies; Collagen Type I; Female; Humans; Male; Pragmatic Clinical Trials as Topic; Prospective Studies; Wound Healing | 2020 |
Tolerability and safety of urotainer® polihexanide 0.02% in catheterized patients: a prospective cohort study.
Topics: Aged; Biguanides; Catheters, Indwelling; Cohort Studies; Disinfectants; Female; Humans; Male; Middle Aged; Prospective Studies; Solutions; Therapeutic Irrigation; Urinary Catheters | 2020 |
Synergistic Effect and Antibiofilm Activity of a Skin and Wound Cleanser.
Topics: Biguanides; Biofilms; Detergents; Drug Synergism; Edetic Acid; Glyceryl Ethers; Humans; Methicillin-Resistant Staphylococcus aureus; Octanols; Pseudomonas aeruginosa; Skin; Wounds and Injuries | 2020 |
Endotheliitis-A Presentation of Acanthamoeba Keratitis.
Topics: Acanthamoeba Keratitis; Administration, Ophthalmic; Adult; Antiprotozoal Agents; Benzamidines; Biguanides; Contact Lenses, Hydrophilic; Disinfectants; Endothelium, Corneal; Female; Humans; Inflammation; Male; Microscopy, Confocal; Middle Aged; Ophthalmic Solutions; Polymerase Chain Reaction | 2021 |
Maintenance of indwelling urinary catheters with a novel polyhexanide-based solution: user experience.
Topics: Biguanides; Catheter-Related Infections; Catheters, Indwelling; Female; Humans; Male; Quality of Life; Retrospective Studies; Urinary Catheterization; Urinary Catheters; Urinary Tract Infections | 2020 |
Acanthamoeba Keratitis: Perspectives for Patients.
Topics: Acanthamoeba Keratitis; Adolescent; Adult; Aged; Antiprotozoal Agents; Benzamidines; Biguanides; Child; Contact Lenses; Corneal Ulcer; Disinfectants; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prognosis; Quality of Life; Retrospective Studies; Risk Factors; Time Factors; Visual Acuity; Wound Healing; Young Adult | 2021 |
Cellular gene delivery via poly(hexamethylene biguanide)/pDNA self-assembled nanoparticles.
Topics: Biguanides; Cell Survival; Drug Carriers; Genetic Therapy; HEK293 Cells; HeLa Cells; Hep G2 Cells; Humans; Nanoparticles; Oligodeoxyribonucleotides; Particle Size; Plasmids; Toxicity Tests, Acute; Transfection | 2021 |
Efficacy of Wound Cleansers on Wound-Specific Organisms Using In Vitro and Ex Vivo Biofilm Models.
Topics: Animals; Biguanides; Biofilms; Detergents; Disease Models, Animal; Methicillin-Resistant Staphylococcus aureus; Silver; Sodium Hypochlorite; Swine; Wound Healing | 2020 |
Efficacy of universal preoperative decolonization with Polyhexanide in primary joint arthroplasty on surgical site infections. A multicenter before-and after-study.
Topics: Aged; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Biguanides; Female; Humans; Male; Middle Aged; Preoperative Care; Staphylococcus aureus; Surgical Wound Infection | 2020 |
Synthesis and characterization of an anti-caries and remineralizing fluorine-containing cationic polymer PHMB-F.
Topics: Biguanides; Cariostatic Agents; Dental Caries; Fluorides; Fluorine; Humans; Polymers; Tooth Remineralization | 2021 |
Anti-Biofilm Effect of Octenidine and Polyhexanide on Uropathogenic Biofilm-Producing Bacteria.
Topics: Anti-Infective Agents, Local; Biguanides; Biofilms; Disinfectants; Escherichia coli; Imines; Microbial Sensitivity Tests; Proteus mirabilis; Pseudomonas aeruginosa; Pyridines; Urinary Catheters; Urinary Tract Infections | 2021 |
Effect of Polyhexamethylene Biguanide in Combination with Undecylenamidopropyl Betaine or PslG on Biofilm Clearance.
Topics: Bacteria; Bacterial Infections; Betaine; Biguanides; Biofilms; Candida albicans; Candidiasis; Cross Infection; Disinfectants; Glycoside Hydrolases; Humans; Pseudomonas aeruginosa; Undecylenic Acids | 2021 |
Allergic contact dermatitis caused by polyhexamethylene biguanide may contribute to work-related hand eczema.
Topics: Biguanides; Dermatitis, Allergic Contact; Dermatitis, Occupational; Disinfectants; Hand Dermatoses; Humans; Patch Tests | 2021 |
Therapeutic Ultrasound-Enhanced Transcorneal PHMB Delivery In Vitro.
Topics: Biguanides; Cornea; Drug Delivery Systems; Ultrasonic Therapy | 2021 |
Response to 'Comment on: 'A randomized masked pilot clinical trial to compare the efficacy of topical 1% Voriconazole ophthalmic solution as monotherapy to combination therapy with topical 0.02% Polyhexamethylene biguanide and 0.02% Chlorhexidine in the t
Topics: Acanthamoeba Keratitis; Biguanides; Chlorhexidine; Humans; Ophthalmic Solutions; Voriconazole | 2022 |
Comment on: 'A randomized masked pilot clinical trial to compare the efficacy of topical 1% voriconazole ophthalmic solution as monotherapy with combination therapy of topical 0.02% polyhexamethylene biguanide and 0.02% chlorhexidine in the treatment of A
Topics: Acanthamoeba Keratitis; Biguanides; Chlorhexidine; Humans; Ophthalmic Solutions; Voriconazole | 2022 |
Fabrication of a Dual-Action Membrane with Both Antibacterial and Anticoagulant Properties via Cationic Polyelectrolyte-Induced Phase Separation.
Topics: Animals; Anti-Bacterial Agents; Anticoagulants; Biguanides; Biocompatible Materials; Humans; Membranes, Artificial; Permeability; Phase Transition; Polyelectrolytes; Polymers; Rabbits; Sulfones; Sulfonic Acids | 2021 |
Antibacterial efficacy of poly(hexamethylene biguanide) immobilized on chitosan/dye-modified nanofiber membranes.
Topics: Anti-Bacterial Agents; Biguanides; Chitosan; Coloring Agents; Escherichia coli; Hydrogen-Ion Concentration; Kinetics; Membranes, Artificial; Microbial Sensitivity Tests; Nanofibers; Spectroscopy, Fourier Transform Infrared | 2021 |
In vitro efficacy of a 0.2% polyhexamethylene biguanide-impregnated gauze dressing against pathogenic bacterial isolates found in horses.
Topics: Animals; Bandages; Biguanides; Disinfectants; Escherichia coli; Escherichia coli Infections; Horse Diseases; Horses; Staphylococcal Infections; Staphylococcus; Surgical Wound Infection | 2021 |
Biofilm reduction potential of 0.02% polyhexanide irrigation solution in several types of urethral catheters.
Topics: Biguanides; Biofilms; Disinfectants; Equipment Contamination; Humans; Therapeutic Irrigation; Urinary Catheters | 2021 |
Long-Term Outcome Assessment Between Antiseptic and Normal Saline for Negative Pressure Wound Therapy with Instillation.
Topics: Adult; Aged; Aged, 80 and over; Anti-Infective Agents, Local; Betaine; Biguanides; Female; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Negative-Pressure Wound Therapy; Outcome Assessment, Health Care; Retrospective Studies; Saline Solution; Wound Healing | 2021 |
Efficacy of common antiseptic solutions against clinically relevant microorganisms in biofilm.
Topics: Acetic Acid; Anti-Bacterial Agents; Anti-Infective Agents, Local; Arthroplasty, Replacement; Benzalkonium Compounds; Betaine; Biguanides; Biofilms; Chlorhexidine; Hydrogen Peroxide; In Vitro Techniques; Methicillin-Resistant Staphylococcus aureus; Povidone-Iodine; Propionibacteriaceae; Prosthesis-Related Infections; Pseudomonas aeruginosa; Sodium Hypochlorite; Staphylococcus epidermidis | 2021 |
Antimicrobial effectiveness of wound matrices containing native extracellular matrix with polyhexamethylene biguanide.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Biguanides; Extracellular Matrix; Humans; Methicillin-Resistant Staphylococcus aureus; Swine | 2022 |
Antibiofilm Efficacy of Polihexanide, Octenidine and Sodium Hypochlorite/Hypochlorous Acid Based Wound Irrigation Solutions against Staphylococcus aureus, Pseudomonas aeruginosa and a Multispecies Biofilm.
Topics: Biguanides; Biofilms; Humans; Hypochlorous Acid; Imines; Pseudomonas aeruginosa; Pyridines; Sodium Hypochlorite; Staphylococcal Infections; Staphylococcus aureus; Water | 2022 |
Dynamic and quantitative characterization of antagonism within disinfectant mixtures by a modified area-concentration ratio method.
Topics: Biguanides; Calcium Compounds; Chlorhexidine; Disinfectants; Drug Interactions; Environmental Pollutants; Vibrio | 2021 |
Fabrication of collagen with polyhexamethylene biguanide: A potential scaffold for infected wounds.
Topics: Anti-Bacterial Agents; Bandages; Biguanides; Collagen; Humans; Wound Infection | 2022 |
Bilateral radial keratoneuritis resulting from acanthamoeba keratitis.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adolescent; Anti-Infective Agents, Local; Biguanides; Chlorhexidine; Contact Lenses; Cornea; Disinfectants; Female; Humans; Photophobia | 2022 |
Synergism versus Additivity: Defining the Interactions between Common Disinfectants.
Topics: Acinetobacter baumannii; Benzalkonium Compounds; Biguanides; Cresols; Disinfectants; Drug Synergism; Enterococcus faecalis; Klebsiella pneumoniae; Microbial Sensitivity Tests; Propylene Glycols; Quaternary Ammonium Compounds; Staphylococcus aureus | 2021 |
Isolation and Characterization of the Polyhexamethylene Biguanide Hydrochloride-Resistant Fungus, Purpureocillium lilacinum.
Topics: Biguanides; Fungi; Hypocreales; Microbial Sensitivity Tests | 2021 |
Anti-fibrotic effect of pycnogenol® in a polyhexamethylene guanidine-treated mouse model.
Topics: Animals; Anti-Inflammatory Agents; Biguanides; Disease Models, Animal; Flavonoids; Inflammation; Male; Mice; Mice, Inbred C57BL; Plant Extracts; Pulmonary Fibrosis | 2022 |
Mechanical, antibacterial, biocompatible and microleakage evaluation of glass ionomer cement modified by nanohydroxyapatite/polyhexamethylene biguanide.
Topics: Anti-Bacterial Agents; Biguanides; Glass Ionomer Cements; Materials Testing | 2022 |
Cytochrome P450 monooxygenase of Acanthamoeba castellanii participates in resistance to polyhexamethylene biguanide treatment.
Topics: Acanthamoeba castellanii; Amebiasis; Biguanides; Cytochrome P-450 Enzyme System; Humans | 2021 |
Triple relevant sensitization to didecyldimethylammonium chloride, benzalkonium chloride, and polyhexamethylene biguanide in a hospital cleaner.
Topics: Benzalkonium Compounds; Biguanides; Dermatitis, Allergic Contact; Hospitals; Humans; Quaternary Ammonium Compounds | 2022 |
Mast cell activation test: A new asset in the investigation of the chlorhexidine cross-sensitization profile.
Topics: Biguanides; Cell Degranulation; Chlorhexidine; Humans; Hypersensitivity; Immunoglobulin E; Mast Cells; Nerve Tissue Proteins; Receptors, G-Protein-Coupled; Receptors, Neuropeptide | 2022 |
Effectiveness of type I collagen matrix plus polyhexamethylene biguanide antimicrobial for the treatment of pressure injuries.
Topics: Aged; Anti-Bacterial Agents; Biguanides; Collagen Type I; Female; Humans; Male; Pressure Ulcer; Prospective Studies; Wound Healing | 2022 |
A Prospective Noninterventional Study of Type I Collagen Matrix Plus Polyhexamethylene Biguanide Antimicrobial for the Treatment of Venous Leg Ulcers: A Secondary Analysis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Biguanides; Collagen Type I; Humans; Prospective Studies; Varicose Ulcer; Wound Healing | 2022 |
Modulatory Contribution of Oxygenating Hydrogels and Polyhexamethylene Biguanide on the Antimicrobial Potency of Neutrophil-like Cells.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biguanides; Chitosan; Humans; Hydrogels; Neutrophils; Oxygen; Reactive Oxygen Species | 2022 |
Mechanism of Polyhexamethylene Biguanide Resistance in Purpureocillium lilacinum Strains.
Topics: Adenosine; Adenosine Deaminase; AMP Deaminase; Biguanides; Carboxy-Lyases; Hypocreales; Uracil; Uridine | 2022 |
Fungal cell barriers and organelles are disrupted by polyhexamethylene biguanide (PHMB).
Topics: Animals; Anti-Infective Agents; Antifungal Agents; Biguanides; Mammals; Microbial Sensitivity Tests; Organelles; Saccharomyces cerevisiae | 2023 |
Ex vivo wound model on porcine skin for the evaluation of the antibiofilm activity of polyhexamethylene biguanide and ciprofloxacin.
Topics: Animals; Anti-Bacterial Agents; Biguanides; Biofilms; Ciprofloxacin; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Swine | 2023 |
Effectiveness of a purified type I collagen matrix plus the antimicrobial polyhexamethylene biguanide for use in cutaneous wounds: analysis of a population of three combined registries.
Topics: Anti-Infective Agents; Biguanides; Collagen Type I; Diabetic Foot; Female; Humans; Hypoglycemic Agents; Male; Soft Tissue Injuries; Treatment Outcome; Wound Healing | 2023 |