vanoxerine has been researched along with gbr 12935 in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.00) | 18.7374 |
| 1990's | 12 (48.00) | 18.2507 |
| 2000's | 10 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| de Costa, BR; Dersch, CM; Glowa, JR; Matecka, D; Partilla, JS; Pert, A; Radesca, L; Rice, KC; Rothman, RB; Wojnicki, FH | 1 |
| Dersch, CM; DeVries, AC; Glowa, JR; Lewis, D; Matecka, D; Pert, A; Rice, KC; Rothman, RB; Wojnicki, FH | 1 |
| Hengerer, B; Zimmermann, K | 1 |
| Dersch, CM; Glowa, JR; Hsin, LW; Lewis, DB; Matecka, D; Rice, KC; Rothman, RB; Stafford, D; Zhang, Y | 1 |
| Hoffman, BT; Katz, JL; Kopajtic, T; Newman, AH | 1 |
| Bowen, WD; Dersch, CM; Flippen-Anderson, JL; Jacobson, AE; Joseph, DB; Rice, KC; Rothman, RB; Zhang, Y | 1 |
| Baumann, MH; Dersch, CM; Glowa, JR; Hsin, LW; Jacobson, AE; Rice, KC; Rothman, RB; Stafford, D | 1 |
| Dersch, CM; Jacobson, AE; Lewis, D; Prisinzano, T; Rice, KC; Rothman, RB; Zhang, Y | 1 |
| Chang, LT; Dersch, CM; Hsin, LW; Jacobson, AE; Rice, KC; Rothman, RB | 1 |
| Arroyo, J; Berger, P; Elsworth, JD; Roth, RH | 1 |
| Akunne, H; Greig, N; Mele, A; Pert, A; Reid, AA; Rice, KC; Rothman, RB; Thurkauf, A | 1 |
| Grigoriadis, DE; Kuhar, MJ; Lew, R; Sharkey, J | 1 |
| Andersen, PH | 1 |
| Appleyard, SM; Chavkin, C; Connor, M; Patterson, TA | 1 |
| Gordon, I; Rehavi, M; Weizman, R | 1 |
| Chen, NH; Coffey, LL; Reith, ME; Xu, C | 1 |
| Akunne, HC; de Costa, BR; Dersch, C; Kilburn, RB; Lewis, B; Pert, A; Radesca, L; Rice, KC; Rothman, RB; Xu, H | 1 |
| Azoui, R; Cuche, JL; Dagher, G; Renaud, JF; Safar, M | 1 |
| Choi, SW; Elmaleh, DR; Fischman, AJ; Hanson, RN | 1 |
| Baldessarini, RJ; Fisser, R; Kula, NS; Neumeyer, JL; Tarazi, FI; Trometer, J; Wang, S | 1 |
| Ayestas, MA; Baumann, MH; Dersch, CM; Partilla, JS; Rothman, RB | 1 |
| Engleman, E; McBride, WJ; Rahman, S; Simon, J | 1 |
| Goldberg, SR; Tella, SR | 1 |
| Inazu, M; Kawakatsu, N; Kimura, M; Kishii, K; Kiuchi, Y; Kubota, N; Masuda, T; Mitani, M; Namiki, T; Oguchi, K; Yamada, K | 1 |
| Chen, N; Dutta, AK; Maiti, S; Reith, ME; Zhen, J | 1 |
25 other study(ies) available for vanoxerine and gbr 12935
| Article | Year |
|---|---|
Development of novel, potent, and selective dopamine reuptake inhibitors through alteration of the piperazine ring of 1-[2-(diphenylmethoxy)ethyl]-and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909).
Topics: Animals; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Design; Magnetic Resonance Spectroscopy; Mass Spectrometry; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Conformation; Molecular Structure; Nerve Tissue Proteins; Piperazines; Rats; Receptors, Drug; Serotonin; Substance-Related Disorders | 1996 |
Heteroaromatic analogs of 1-[2-(diphenylmethoxy)ethyl]- and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as high-affinity dopamine reuptake inhibitors.
Topics: Animals; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Feeding Behavior; Ligands; Macaca mulatta; Magnetic Resonance Spectroscopy; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Motor Activity; Nerve Tissue Proteins; Pentazocine; Piperazines; Rats; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship | 1997 |
Design and synthesis of a biotinylated dopamine transporter ligand for the purification and labeling of dopaminergic neurons.
Topics: Animals; Biotin; Carrier Proteins; Cells, Cultured; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ligands; Magnetic Resonance Spectroscopy; Mass Spectrometry; Membrane Glycoproteins; Membrane Transport Proteins; Mesencephalon; Nerve Tissue Proteins; Neurons; Piperazines; Rats | 1998 |
Oxygenated analogues of 1-[2-(Diphenylmethoxy)ethyl]- and 1-[2-[Bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines (GBR 12935 and GBR 12909) as potential extended-action cocaine-abuse therapeutic agents.
Topics: Animals; Carrier Proteins; Cocaine-Related Disorders; Delayed-Action Preparations; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Hydroxylation; Ligands; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylation; Molecular Structure; Nerve Tissue Proteins; Oxygen; Piperazines; Rats; Structure-Activity Relationship; Tritium | 1999 |
2D QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors.
Topics: Algorithms; Binding, Competitive; Carrier Proteins; Databases, Factual; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Quantitative Structure-Activity Relationship; Radioligand Assay; Reproducibility of Results; Software | 2000 |
Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues.
Topics: Animals; Brain; Carrier Proteins; Crystallography, X-Ray; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptors, Muscarinic; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Tropanes | 2001 |
Development of long-acting dopamine transporter ligands as potential cocaine-abuse therapeutic agents: chiral hydroxyl-containing derivatives of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phe
Topics: Animals; Behavior, Animal; Benzhydryl Compounds; Cocaine-Related Disorders; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Ligands; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Piperazines; Propanols; Rats; Rats, Sprague-Dawley; Stereoisomerism | 2002 |
Further exploration of 1-[2-[Bis-(4-fluorophenyl)methoxy]ethyl]piperazine (GBR 12909): role of N-aromatic, N-heteroaromatic, and 3-oxygenated N-phenylpropyl substituents on affinity for the dopamine and serotonin transporter.
Topics: Alcohols; Carrier Proteins; Dopamine Plasma Membrane Transport Proteins; Heterocyclic Compounds; Kinetics; Mannich Bases; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Protein Binding; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship | 2003 |
Design and synthesis of 2- and 3-substituted-3-phenylpropyl analogs of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine and 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine: role of amino, fluoro, hydroxyl, methoxyl, methyl, m
Topics: Dopamine Plasma Membrane Transport Proteins; Piperazines; Radioligand Assay; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Structure-Activity Relationship | 2008 |
Interaction of [3H]GBR 12935 and GBR 12909 with the dopamine uptake complex in nucleus accumbens.
Topics: Animals; Binding, Competitive; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Kinetics; Male; Membrane Proteins; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Nucleus Accumbens; Piperazines; Rats; Rats, Inbred Strains; Septal Nuclei | 1990 |
Tight binding dopamine reuptake inhibitors as cocaine antagonists. A strategy for drug development.
Topics: Animals; Biological Transport; Carrier Proteins; Cell Membrane; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Extracellular Space; Kinetics; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Inbred Strains | 1989 |
Dopamine transporter: solubilization from dog caudate nucleus.
Topics: Animals; Binding, Competitive; Caudate Nucleus; Cerebellum; Digitonin; Dogs; Hot Temperature; Piperazines; Rats; Receptors, Dopamine; Solubility; Subcellular Fractions; Trypsin | 1989 |
Biochemical and pharmacological characterization of [3H]GBR 12935 binding in vitro to rat striatal membranes: labeling of the dopamine uptake complex.
Topics: Animals; Binding Sites; Brain; Corpus Striatum; Dopamine; In Vitro Techniques; Kinetics; Ligands; Methylphenidate; Neurotransmitter Uptake Inhibitors; Piperazines; Rats | 1987 |
Oocytes from Xenopus laevis contain an intrinsic sigma 2-like binding site.
Topics: Animals; Binding Sites; Binding, Competitive; Carbazoles; Dextromethorphan; Female; Guanidines; Haloperidol; Liver; Mazindol; Oocytes; Pentazocine; Phenazocine; Piperazines; Piperidines; Radioligand Assay; Rats; Receptors, sigma; Xenopus laevis; Zinc | 1994 |
[3H]GBR 12935 binding to human platelet membranes is sensitive to piperazine derivatives but not to dopamine uptake inhibitors.
Topics: Animals; Antidepressive Agents; Blood Platelets; Cell Membrane; Corpus Striatum; Dopamine; Humans; Kinetics; Ligands; Male; Mazindol; Neurotransmitter Uptake Inhibitors; Piperazines; Rats | 1994 |
GBR 12909 and 12935 block dopamine uptake into brain synaptic vesicles as well as nerve endings.
Topics: Animals; Brain; Dopamine; Male; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley; Synaptic Vesicles | 1994 |
Identification of a GBR12935 homolog, LR1111, which is over 4,000-fold selective for the dopamine transporter, relative to serotonin and norepinephrine transporters.
Topics: Animals; Azepines; Behavior, Animal; Carrier Proteins; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine Plasma Membrane Transport Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Serotonin Plasma Membrane Transport Proteins; Stereotyped Behavior; Structure-Activity Relationship; Symporters | 1993 |
A dopamine transporter in human erythrocytes: modulation by insulin.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Biological Transport; Carrier Proteins; Catecholamines; Choline; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Epinephrine; Erythrocytes; Humans; Hydrogen-Ion Concentration; Insulin; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Norepinephrine; Piperazines; Probenecid; Reserpine; Time Factors | 1996 |
Design, synthesis, and biological evaluation of novel non-piperazine analogues of 1-[2-(diphenylmethoxy)ethyl]- and 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazines as dopamine transporter inhibitors.
Topics: Amides; Amines; Animals; Biogenic Monoamines; Carrier Proteins; Cell Line; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Heterocyclic Compounds, 1-Ring; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Mice, Inbred Strains; Motor Activity; Nerve Tissue Proteins; Piperazines | 1999 |
[3H]beta-CIT: a radioligand for dopamine transporters in rat brain tissue.
Topics: Amphetamine; Animals; Autoradiography; Binding, Competitive; Brain; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Male; Membrane Glycoproteins; Membrane Transport Proteins; Methylphenidate; Nerve Tissue Proteins; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin Plasma Membrane Transport Proteins; Stereoisomerism; Tritium | 1999 |
Serotonin transporters, serotonin release, and the mechanism of fenfluramine neurotoxicity.
Topics: Analysis of Variance; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Electrochemistry; Fenfluramine; Male; Microdialysis; Models, Neurological; Neurotoxicity Syndromes; Piperazines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Tritium | 2000 |
Negative interaction of dopamine D2 receptor antagonists and GBR 12909 and GBR 12935 dopamine uptake inhibitors in the nucleus accumbens.
Topics: Animals; Dopamine; Dopamine Antagonists; Dopamine Uptake Inhibitors; Drug Interactions; Male; Nucleus Accumbens; Piperazines; Rats; Rats, Wistar; Receptors, Dopamine D2 | 2001 |
Subtle differences in the discriminative stimulus effects of cocaine and GBR-12909.
Topics: Adrenergic Uptake Inhibitors; Animals; Carrier Proteins; Cocaine; Discrimination, Psychological; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors | 2001 |
Novel diphenylalkyl piperazine derivatives with high affinities for the dopamine transporter.
Topics: Animals; Binding, Competitive; Biphenyl Compounds; Cell Membrane; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Inhibitory Concentration 50; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Structure-Activity Relationship | 2003 |
Interaction between a hydroxypiperidine analogue of 4-(2-benzhydryloxy-ethyl)-1-(4-fluorobenzyl)piperidine and Aspartate 68 in the human dopamine transporter.
Topics: Animals; Aspartic Acid; Benzhydryl Compounds; Binding Sites; Binding, Competitive; Biological Transport; Cell Line; Cell Membrane; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutation; Nerve Tissue Proteins; Norepinephrine; Piperazines; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Serotonin; Stereoisomerism; Synaptosomes; Tritium | 2004 |