vanoxerine and benztropine

vanoxerine has been researched along with benztropine in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's7 (38.89)18.2507
2000's7 (38.89)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Allen, AC; George, C; Izenwasser, S; Katz, JL; Kline, RH; Newman, AH1
Allen, AC; Izenwasser, S; Katz, JL; Newman, AH1
Hoffman, BT; Katz, JL; Kopajtic, T; Newman, AH1
Bowen, WD; Dersch, CM; Flippen-Anderson, JL; Jacobson, AE; Joseph, DB; Rice, KC; Rothman, RB; Zhang, Y1
Efthimiopoulos, S; Giompres, P; Valcana, T1
Chilco, PJ; Donnan, GA; Kaczmarczyk, SJ; Kalnins, RM; Mendelsohn, FA; Paxinos, G; Woodhouse, DG1
Kruk, ZL; Millar, J; Stamford, JA1
Kuhr, WG; May, LJ; Wightman, RM1
Hirota, K; Ikegami, H; Jikihara, H; Koike, K; Kurachi, H; Miyake, A; Morishige, K; Tanizawa, O; Wada, K1
Meiergerd, SM; Schenk, JO1
Agoston, GE; Newman, AH1
Agoston, GE; Hecht, GS; Katz, JL; Newman, AH; Woolverton, WL1
Chen, N; Reith, ME; Zhen, J1
Desai, RI; French, D; Katz, JL; Kopajtic, TA; Newman, AH1
Baumann, MH; Newman, AH; Prisinzano, TE; Rothman, RB1
Chen, N; Dutta, AK; Kharkar, P; Mishra, M; Reith, ME; Schmitt, KC; Zhen, J1
Donovan, DM; Katz, JL; Kopajtic, TA; Liu, Y; Newman, AH; Surratt, CK1
Desai, RI; Katz, JL; Slezak, JM1

Reviews

2 review(s) available for vanoxerine and benztropine

ArticleYear
Novel benztropine [3a-(diphenylmethoxy)tropane] analogs as probes for the dopamine transporter.
    Current medicinal chemistry, 1998, Volume: 5, Issue:4

    Topics: Benztropine; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Design; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Stereoisomerism; Structure-Activity Relationship; Substance-Related Disorders

1998
Dopamine transport inhibitors based on GBR12909 and benztropine as potential medications to treat cocaine addiction.
    Biochemical pharmacology, 2008, Jan-01, Volume: 75, Issue:1

    Topics: Animals; Behavior, Animal; Benztropine; Cocaine-Related Disorders; Conditioning, Psychological; Disease Models, Animal; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Humans; Piperazines; Structure-Activity Relationship

2008

Other Studies

16 other study(ies) available for vanoxerine and benztropine

ArticleYear
Novel 4'-substituted and 4',4"-disubstituted 3 alpha-(diphenylmethoxy)tropane analogs as potent and selective dopamine uptake inhibitors.
    Journal of medicinal chemistry, 1995, Sep-29, Volume: 38, Issue:20

    Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Male; Radioligand Assay; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tropanes

1995
Novel 3 alpha-(diphenylmethoxy)tropane analogs: potent dopamine uptake inhibitors without cocaine-like behavioral profiles.
    Journal of medicinal chemistry, 1994, Jul-22, Volume: 37, Issue:15

    Topics: Animals; Behavior, Animal; Benztropine; Cocaine; Dopamine Antagonists; Mice; Rats; Structure-Activity Relationship; Tropanes

1994
2D QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors.
    Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22

    Topics: Algorithms; Binding, Competitive; Carrier Proteins; Databases, Factual; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Quantitative Structure-Activity Relationship; Radioligand Assay; Reproducibility of Results; Software

2000
Synthesis and biological evaluation of tropane-like 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine (GBR 12909) analogues.
    Journal of medicinal chemistry, 2001, Nov-08, Volume: 44, Issue:23

    Topics: Animals; Brain; Carrier Proteins; Crystallography, X-Ray; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Receptors, Muscarinic; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Tropanes

2001
Kinetics of dopamine and noradrenaline transport in synaptosomes from cerebellum, striatum and frontal cortex of normal and reeler mice.
    Journal of neuroscience research, 1991, Volume: 29, Issue:4

    Topics: Animals; Benztropine; Biological Transport; Cerebellum; Cerebral Cortex; Corpus Striatum; Dopamine; Female; In Vitro Techniques; Kinetics; Male; Mice; Mice, Neurologic Mutants; Neurotransmitter Uptake Inhibitors; Nomifensine; Norepinephrine; Piperazines; Reference Values; Synaptosomes

1991
Distribution of catecholamine uptake sites in human brain as determined by quantitative [3H] mazindol autoradiography.
    The Journal of comparative neurology, 1991, Feb-15, Volume: 304, Issue:3

    Topics: Aged; Benztropine; Binding, Competitive; Biological Transport; Brain Chemistry; Brain Mapping; Caudate Nucleus; Citalopram; Clomipramine; Corpus Striatum; Desipramine; Dopamine; Humans; Locus Coeruleus; Mazindol; Medulla Oblongata; Mianserin; Middle Aged; Norepinephrine; Piperazines; Pons; Substantia Nigra

1991
Dissociation of the actions of uptake blockers upon dopamine overflow and uptake in the rat nucleus accumbens: in vivo voltammetric data.
    Neuropharmacology, 1989, Volume: 28, Issue:12

    Topics: Animals; Benztropine; Bupropion; Cocaine; Dopamine; Electric Stimulation; Electrochemistry; Levodopa; Male; Microelectrodes; Neurotransmitter Uptake Inhibitors; Nomifensine; Nucleus Accumbens; Piperazines; Propiophenones; Rats; Rats, Inbred Strains; Septal Nuclei

1989
Differentiation of dopamine overflow and uptake processes in the extracellular fluid of the rat caudate nucleus with fast-scan in vivo voltammetry.
    Journal of neurochemistry, 1988, Volume: 51, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Benztropine; Bupropion; Caudate Nucleus; Dopamine; Electric Stimulation; Electrochemistry; Extracellular Space; Kinetics; Levodopa; Male; Microelectrodes; Neurotransmitter Uptake Inhibitors; Nomifensine; Piperazines; Propiophenones; Rats; Rats, Inbred Strains

1988
Intraventricular administration of histidyl-proline-diketopiperazine [Cyclo(His-Pro)] suppresses prolactin secretion and synthesis: a possible role of Cyclo(His-Pro) as dopamine uptake blocker in rat hypothalamus.
    Endocrinology, 1993, Volume: 132, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benztropine; Blotting, Northern; Cells, Cultured; Cerebral Ventricles; Dopamine; Dopamine Antagonists; Female; Hypothalamus; Infusions, Parenteral; Kinetics; Neurotransmitter Uptake Inhibitors; Peptides, Cyclic; Piperazines; Pituitary Gland, Anterior; Prolactin; Rats; Rats, Wistar; RNA; Transcription, Genetic

1993
Kinetic evaluation of the commonality between the site(s) of action of cocaine and some other structurally similar and dissimilar inhibitors of the striatal transporter for dopamine.
    Journal of neurochemistry, 1994, Volume: 63, Issue:5

    Topics: Animals; Benztropine; Biological Transport; Cocaine; Corpus Striatum; Dopamine; Male; Mazindol; Models, Biological; Neurotransmitter Uptake Inhibitors; Nomifensine; Piperazines; Rats; Rats, Sprague-Dawley

1994
Further studies of the reinforcing effects of benztropine analogs in rhesus monkeys.
    Psychopharmacology, 2001, Volume: 154, Issue:4

    Topics: Animals; Benztropine; Cocaine; Dopamine Uptake Inhibitors; Female; Macaca mulatta; Male; Piperazines; Reaction Time; Reinforcement Schedule; Self Administration

2001
Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.
    Journal of neurochemistry, 2004, Volume: 89, Issue:4

    Topics: Amino Acid Substitution; Benztropine; Binding, Competitive; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Kidney; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Muscarinic Antagonists; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Piperazines; Protein Binding; Sodium; Structure-Activity Relationship; Zinc

2004
Relationship between in vivo occupancy at the dopamine transporter and behavioral effects of cocaine, GBR 12909 [1-{2-[bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and benztropine analogs.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 315, Issue:1

    Topics: Animals; Benztropine; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Mice; Motor Activity; Piperazines

2005
Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties.
    Journal of neurochemistry, 2008, Volume: 107, Issue:4

    Topics: Animals; Asparagine; Aspartic Acid; Benztropine; Binding, Competitive; Cell Line, Transformed; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Leucine; Models, Molecular; Mutation; Piperazines; Protein Binding; Protein Structure, Tertiary; Sodium; Structure-Activity Relationship; Transfection; Tritium; Tryptophan

2008
Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 335, Issue:3

    Topics: Adrenergic Uptake Inhibitors; Animals; Benztropine; Binding, Competitive; Cell Line, Tumor; Cell Membrane; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Histamine H1 Antagonists; Humans; Kinetics; Male; Mice; Mice, 129 Strain; Mice, Inbred Strains; Mice, Knockout; Neuroblastoma; Piperazines; Pirenzepine; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Selective Serotonin Reuptake Inhibitors; Sodium; Triprolidine

2010
Further delineation between typical and atypical dopamine uptake inhibitors: effects on food-maintained behavior and food consumption.
    Behavioural pharmacology, 2017, Volume: 28, Issue:1

    Topics: Animals; Behavior, Animal; Benztropine; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Eating; Feeding Behavior; Male; Piperazines; Rats; Rats, Sprague-Dawley; Reinforcement Schedule

2017