vanillic acid has been researched along with kutkin in 69 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (1.45) | 18.7374 |
| 1990's | 31 (44.93) | 18.2507 |
| 2000's | 26 (37.68) | 29.6817 |
| 2010's | 9 (13.04) | 24.3611 |
| 2020's | 2 (2.90) | 2.80 |
| Authors | Studies |
|---|---|
| Dhawan, BN; Kapoor, NK; Patnaik, GK; Singh, V; Visen, PK | 1 |
| Chander, R; Dhawan, BN; Kapoor, NK | 3 |
| Dhawan, BN; Dwivedi, Y; Garg, NK; Rastogi, R | 3 |
| Dhawan, BN; Guru, PY; Kulshreshtha, DK; Puri, A; Saxena, KC; Saxena, RP | 1 |
| Dhawan, BN; Kapoor, NK; Singh, V | 1 |
| Ansari, RA; Dhawan, BN; Patnaik, GK; Tripathi, SC | 1 |
| Dhawan, BN; Dwivedi, Y; Garg, NK; Mehrotra, R; Rastogi, R; Sharma, SK | 1 |
| Dhawan, BN; Dwivedi, Y; Garg, NK; Rastogi, R; Sharma, SK | 1 |
| Dhawan, BN; Patnaik, GK; Shukla, B; Visen, PK | 2 |
| Chander, R; Dhawan, BN; Dwivedi, Y; Garg, NK; Kapoor, NK; Rastogi, R; Sharma, SK | 2 |
| Bieri, A; Floersheim, GL; Koenig, R; Pletscher, A | 1 |
| Dhawan, BN; Kulshreshtha, DK; Mehrotra, R; Patnaik, GK; Rawat, S | 1 |
| Ansari, RA; Aswal, BS; Chander, R; Dhawan, BN; Garg, NK; Kapoor, NK; Kulshreshtha, DK; Mehdi, H; Mehrotra, BN; Patnaik, GK | 1 |
| Dhawan, BN; Patnaik, GK; Saraswat, B; Visen, PK | 3 |
| Agarwal, DP; Dhawan, BN; Garg, NK; Kapoor, NK; Rastogi, R; Saksena, S | 1 |
| Utrilla, MP | 1 |
| Das, S; Maity, A; Mazumder, DN; Rao, SB; Santra, A | 1 |
| Chander, R; Dhawan, BN; Kapoor, NK; Singh, K; Visen, PK | 1 |
| Bala, L; Dhawan, BN; Jaiswal, AK; Mehrotra, J; Sinha, S | 1 |
| Goyal, N; Gupta, N; Mittal, N; Rastogi, AK; Roy, U; Saksena, S | 1 |
| Baruah, CC; Dhawan, BN; Gupta, PP; Nath, A; Patnaik, LG | 1 |
| Dhawan, BN; Saraswat, B; Visen, PK | 1 |
| Gaddipati, JP; Madhavan, S; Maheshwari, RK; Seth, P; Sidhu, GS; Singh, AK | 1 |
| Banaudha, KK; Kulshreshtha, DK; Kumari, R; Madhavan, S; Maheshwari, RK; Mani, H; Seth, P; Sharma, SC; Singh, AK | 1 |
| Banuadha, KK; Gaddipati, JP; Kulshreshtha, DK; Kumari, R; Maheshwari, RK; Mani, H; Seth, P; Sharma, SC; Singh, AK | 1 |
| Rastogi, AK; Rastogi, R; Srivastava, AK | 2 |
| Rastogi, AK; Rastogi, R; Srivastava, AK; Srivastava, M | 1 |
| Banaudha, KK; Gaddipati, JP; Kulshreshtha, DK; Maheshwari, RK; Mani, H; Sharma, SK | 1 |
| Kuttan, R; Rajeshkumar, NV | 3 |
| Kulshreshtha, DK; Maheshwari, RK; Seth, P; Seth, RK; Sharma, SC; Sidhu, GS; Sundar, SV | 1 |
| Gupta, RC; Kumar, V; Lal, J; Mehrotra, N | 1 |
| Gupta, S; Ramesh, SC; Srivastava, VM | 1 |
| Ghoshal, S; Jain, A; Singh, M; Tiwari, V | 1 |
| Dogra, RK; Khan, MY; Khandelwal, S; Yadav, N | 1 |
| Khandelwal, S; Yadav, N | 3 |
| Gaddipati, J; Kulshreshtha, DK; Madhavan, S; Maheshwari, RK; RajeshKumar, NV; Sharma, A; Sharma, SC; Singh, AK; Steele, K; Thangapazham, RL; Warren, J | 1 |
| Gobianand, K; Karthikeyan, S; Priya, S; Vijayalakshmi, P; Vivekanandan, P | 1 |
| Dangi, A; Dwivedi, V; Fatima, N; Khan, A; Misra-Bhattacharya, S; Owais, M; Soni, VK; Vasco, A | 1 |
| Khandelwal, S; Pathak, N | 1 |
| Aggarwal, BB; Ahn, KS; Anand, P; Badmaev, V; Harikumar, KB; Kunnumakkara, AB | 1 |
| Girish, C; Pradhan, SC | 1 |
| Harikumar, KB; Kuttan, G; Kuttan, R | 1 |
| Basu, V; Gupta, V; Rahman, LU; Saxena, G; Verma, PC | 1 |
| Girish, C; Jayanthi, S; Koner, BC; Pradhan, SC; Rajesh, B; Ramachandra Rao, K | 1 |
| Gupta, S; Sane, SA; Shakya, N | 2 |
| Bajpai, P; Gupta, S; Sane, SA; Shakya, N; Vishwakarma, P | 1 |
| Feng, YH; Li, YM; Wang, X; Wei, LN; Yu, JJ; Yu, Y; Zhang, DK | 1 |
| Anandjiwala, S; Dash, RP; Nivsarkar, M; Upadhyay, D | 1 |
| Banerjee, S; Negi, AS; Rahman, LU; Saxena, G; Singh, H; Verma, PC | 1 |
| Anandjiwala, S; Nivsarkar, M; Padh, H; Upadhyay, D | 1 |
| Guliani, A; Kumar, D; Kumari, A; Yadav, SK | 1 |
| Jin, X; Li, L; Yin, J; Zhang, H | 1 |
| Balapure, AK; Misra, A; Sarkar, E; Trivedi, A | 1 |
| Kumar, D; Kumar, S; Padwad, Y; Purohit, R; Rawat, B; Singh, R; Sinha, K | 1 |
2 review(s) available for vanillic acid and kutkin
| Article | Year |
|---|---|
Drug development for liver diseases: focus on picroliv, ellagic acid and curcumin.
Topics: Animals; Cinnamates; Clinical Trials as Topic; Curcumin; Drug Discovery; Glycosides; Humans; Hydrolyzable Tannins; Liver; Liver Diseases; Plant Preparations; Protective Agents; Treatment Outcome; Vanillic Acid | 2008 |
Pharmacology and chemistry of a potent hepatoprotective compound Picroliv isolated from the roots and rhizomes of Picrorhiza kurroa royle ex benth. (kutki).
Topics: Animals; Cinnamates; Glycosides; Humans; Liver; Liver Diseases; Picrorhiza; Plant Extracts; Plant Roots; Vanillic Acid | 2009 |
67 other study(ies) available for vanillic acid and kutkin
| Article | Year |
|---|---|
Effect of picroliv on low density lipoprotein receptor binding of rat hepatocytes in hepatic damage induced by paracetamol.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Cell Survival; Cells, Cultured; Cinnamates; Glycosides; Humans; Lipoproteins, LDL; Liver; Male; Plant Extracts; Rats; Rats, Inbred Strains; Receptors, LDL; Vanillic Acid | 1992 |
Picroliv, picroside-I and kutkoside from Picrorhiza kurrooa are scavengers of superoxide anions.
Topics: Animals; Cinnamates; Free Radical Scavengers; Glycosides; Lipid Peroxidation; Malondialdehyde; Microsomes, Liver; Plant Extracts; Rats; Superoxides; Vanillic Acid; Vitamin E; Xanthine Oxidase | 1992 |
Picroliv and its components kutkoside and picroside I protect liver against galactosamine-induced damage in rats.
Topics: 5'-Nucleotidase; Animals; Cinnamates; Galactosamine; Glycosides; Liver; Male; Phosphoric Monoester Hydrolases; Rats; Rats, Sprague-Dawley; Transaminases; Vanillic Acid | 1992 |
Effects of picroliv, the active principle of Picrorhiza kurroa, on biochemical changes in rat liver poisoned by Amanita phalloides.
Topics: Amanita; Animals; Chemical and Drug Induced Liver Injury; Cinnamates; gamma-Glutamyltransferase; Glycosides; Liver Glycogen; Male; Mushroom Poisoning; Oxidoreductases; Phosphoric Monoester Hydrolases; Rats; Rats, Inbred Strains; Vanillic Acid | 1992 |
Effect of picroliv on glutathione metabolism in liver and brain of Mastomys natalensis infected with Plasmodium berghei.
Topics: Animals; Brain; Cinnamates; Glutathione; Glycosides; Lipid Peroxidation; Liver; Malaria; Male; Muridae; Plant Extracts; Plasmodium berghei; Vanillic Acid | 1992 |
Immunostimulant activity of Picroliv, the iridoid glycoside fraction of Picrorhiza kurroa, and its protective action against Leishmania donovani infection in hamsters.
Topics: Adjuvants, Immunologic; Animals; Antigens, Protozoan; Cinnamates; Cricetinae; Female; Glycosides; Leishmania donovani; Leishmaniasis, Visceral; Male; Mesocricetus; Mice; Mice, Inbred BALB C; Plants, Medicinal; Vanillic Acid | 1992 |
Effect of picroliv on protein and nucleic acid synthesis.
Topics: Animals; Cinnamates; Glycosides; Liver; Male; Nucleic Acids; Plant Extracts; Protein Biosynthesis; Proteins; Rats; Rats, Inbred Strains; Silymarin; Vanillic Acid | 1992 |
Antihepatotoxic properties of picroliv: an active fraction from rhizomes of Picrorhiza kurrooa.
Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cinnamates; Galactosamine; Glycosides; India; Liver; Liver Function Tests; Male; Plant Extracts; Plants, Medicinal; Rats; Rats, Inbred Strains; Silymarin; Vanillic Acid | 1991 |
Picroliv protects against monocrotaline-induced hepatic damage in rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cinnamates; Glycosides; Liver Diseases; Male; Monocrotaline; Plant Extracts; Pyrrolizidine Alkaloids; Rats; Rats, Inbred Strains; Vanillic Acid | 1991 |
Picroliv affords protection against thioacetamide-induced hepatic damage in rats.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cinnamates; Glycosides; Liver Diseases; Male; Rats; Rats, Inbred Strains; Silymarin; Thioacetamide; Vanillic Acid | 1991 |
Choleretic effect of picroliv, the hepatoprotective principle of Picrorhiza kurroa.
Topics: Acetaminophen; Animals; Cholagogues and Choleretics; Cholestasis; Cinnamates; Female; Glycosides; Guinea Pigs; Male; Molecular Structure; Rats; Silymarin; Vanillic Acid | 1991 |
Evaluation of hepatoprotective activity of picroliv (from Picrorhiza kurroa) in Mastomys natalensis infected with Plasmodium berghei.
Topics: Animals; Cinnamates; Glycosides; Liver Diseases, Parasitic; Malaria; Male; Muridae; Plant Extracts; Plasmodium berghei; Vanillic Acid | 1990 |
Protection against Amanita phalloides by the iridoid glycoside mixture of Picrorhiza kurroa (kutkin).
Topics: Amanita; Animals; Cinnamates; Female; Glycosides; Hydroxybenzoates; Mice; Mushroom Poisoning; Silymarin; Vanillic Acid | 1990 |
In vitro studies on the effect of certain natural products against hepatitis B virus.
Topics: Adult; Child; Cinnamates; Female; Glycosides; Hepatitis Antibodies; Hepatitis B; Hepatitis B e Antigens; Hepatitis B Surface Antigens; Hepatitis B virus; Humans; Liver Cirrhosis; Male; Medicine, Traditional; Plant Extracts; Vanillic Acid | 1990 |
Hepatoprotective activity of picroliv against carbon tetrachloride-induced liver damage in rats.
Topics: Animals; Carbon Tetrachloride; Cinnamates; Enzymes; Glycosides; Lipid Metabolism; Liver; Male; Plant Extracts; Rats; Vanillic Acid | 1990 |
Hepatoprotective activity of kutkin--the iridoid glycoside mixture of Picrorhiza kurrooa.
Topics: Animals; Cinnamates; Female; Galactosamine; Glycosides; Hydroxybenzoates; Liver Diseases; Malaria; Male; Muridae; Plasmodium berghei; Rats; Rats, Inbred Strains; Vanillic Acid | 1988 |
Picroliv affects gamma-glutamyl cycle in liver and brain of Mastomys natalensis infected with Plasmodium berghei.
Topics: Animals; Brain; Cinnamates; gamma-Glutamyltransferase; Glycosides; Liver; Malaria; Male; Muridae; Plant Extracts; Plasmodium berghei; Vanillic Acid | 1994 |
Perfusion with picroliv reverses biochemical changes induced in livers of rats toxicated with galactosamine or thioacetamide.
Topics: Animals; Cinnamates; Galactosamine; Glycosides; Liver; Male; Perfusion; Rats; Thioacetamide; Vanillic Acid | 1993 |
Anticholestatic effect of picroliv, active hepatoprotective principle of Picrorhiza kurrooa, against carbon tetrachloride induced cholestasis.
Topics: Animals; Bile Acids and Salts; Carbon Tetrachloride; Cats; Cholestasis; Cinnamates; Dose-Response Relationship, Drug; Female; Glycosides; Guinea Pigs; Male; Plant Extracts; Rats; Silymarin; Vanillic Acid | 1993 |
Prevention of galactosamine-induced hepatic damage by picroliv: study on bile flow and isolated hepatocytes (ex vivo).
Topics: Animals; Bile; Chemical and Drug Induced Liver Injury; Cinnamates; Female; Galactosamine; Glycosides; In Vitro Techniques; Liver Diseases; Male; Plant Extracts; Rats; Silymarin; Vanillic Acid | 1993 |
Picroliv protects against alcohol-induced chronic hepatotoxicity in rats.
Topics: Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Animals; Antioxidants; Cinnamates; Ethanol; Glycosides; Liver; Liver Diseases, Alcoholic; Male; Plant Extracts; Plants, Medicinal; Rats; Vanillic Acid | 1996 |
Natural products with hepatoprotective action.
Topics: Chemical and Drug Induced Liver Injury; Cinnamates; Glycosides; Humans; Liver; Plant Extracts; Plants, Medicinal; Silymarin; Vanillic Acid | 1996 |
Prevention of carbon tetrachloride-induced hepatic injury in mice by Picrorhiza kurrooa.
Topics: Animals; Carbon Tetrachloride Poisoning; Chemical and Drug Induced Liver Injury; Cinnamates; Glycosides; Mice; Mice, Inbred BALB C; Plant Extracts; Vanillic Acid | 1998 |
Protective effect of picroliv, active constituent of Picrorhiza kurrooa, against oxytetracycline induced hepatic damage.
Topics: Animals; Cinnamates; Female; Glycosides; India; Liver; Male; Oxytetracycline; Plant Extracts; Rats; Silymarin; Vanillic Acid | 1997 |
Picroliv prevents oxidation in serum lipoprotein lipids of Mastomys coucha infected with Plasmodium berghei.
Topics: Animals; Cells, Cultured; Cinnamates; Glycosides; Lipid Peroxidation; Lipoproteins, HDL; Lipoproteins, LDL; Malaria; Muridae; Plant Extracts; Plasmodium berghei; Rats; Vanillic Acid | 1998 |
Picroliv, the iridoid glycoside fraction of Picrorhiza kurroa, selectively augments human T cell response to mycobacterial protein antigens.
Topics: Antigens, Bacterial; Antiprotozoal Agents; Cinnamates; Glycosides; Humans; Lymphocyte Activation; Plant Extracts; Plants, Medicinal; T-Lymphocytes; Vanillic Acid | 1998 |
Protective effect of Picroliv from Picrorhiza kurroa against Leishmania donovani infections in Mesocricetus auratus.
Topics: Administration, Oral; Animals; Antimony Sodium Gluconate; Antiprotozoal Agents; Bilirubin; Cinnamates; Cricetinae; Drug Therapy, Combination; Glucose-6-Phosphatase; Glutamate Synthase; Glycosides; Leishmania donovani; Leishmaniasis, Visceral; Lipid Peroxidation; Liver; Mesocricetus; Plant Extracts; Succinate Dehydrogenase; Vanillic Acid | 1998 |
Anti-allergic and anti-anaphylactic activity of picroliv--a standardised iridoid glycoside fraction of Picrorhiza kurroa.
Topics: Animals; Bronchial Spasm; Cinnamates; Dose-Response Relationship, Drug; Female; Glycosides; Guinea Pigs; Histamine Antagonists; Ileum; In Vitro Techniques; Male; Mast Cells; Mice; Plant Extracts; Rats; Rats, Sprague-Dawley; Vanillic Acid | 1998 |
Curative effect of picroliv on primary cultured rat hepatocytes against different hepatotoxins: an in vitro study.
Topics: Animals; Carbon Tetrachloride; Cell Survival; Cells, Cultured; Cinnamates; Dose-Response Relationship, Drug; Female; Galactosamine; Glycosides; Liver; Male; Plant Extracts; Rats; Thioacetamide; Vanillic Acid | 1998 |
Picroliv -- a natural product protects cells and regulates the gene expression during hypoxia/reoxygenation.
Topics: Base Sequence; Blotting, Northern; Cell Hypoxia; Cell Survival; Cinnamates; DNA Primers; Endothelial Growth Factors; Gene Expression Regulation; Glycosides; Humans; L-Lactate Dehydrogenase; Lymphokines; Oxygen; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Vanillic Acid; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 1999 |
Ex vivo and in vivo investigations of picroliv from Picrorhiza kurroa in an alcohol intoxication model in rats.
Topics: Alanine Transaminase; Aldehyde Dehydrogenase; Aldehyde Oxidoreductases; Alkaline Phosphatase; Animals; Antiprotozoal Agents; Aspartate Aminotransferases; Bile; Bile Acids and Salts; Cells, Cultured; Cholestasis; Cinnamates; Ethanol; Glycosides; Liver; Male; Oxygen; Rats; Vanillic Acid | 1999 |
Prevention of renal ischemia-reperfusion-induced injury in rats by picroliv.
Topics: Animals; Apoptosis; Cinnamates; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glycosides; Intercellular Adhesion Molecule-1; Kidney Diseases; Male; Malondialdehyde; Nitric Oxide; Protective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Superoxide Dismutase; Vanillic Acid | 2000 |
Picroliv preconditioning protects the rat liver against ischemia-reperfusion injury.
Topics: Animals; Apoptosis; Caspase 1; Caspase 2; Caspases; Cinnamates; Gene Expression Regulation; Glycosides; Immunohistochemistry; Interleukin-1; Lipid Peroxidation; Liver; Liver Glycogen; Liver Regeneration; Male; Microscopy, Electron, Scanning; Peroxidase; Plant Extracts; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Superoxide Dismutase; Vanillic Acid | 2000 |
Biochemical changes induced in liver and serum of aflatoxin B1-treated male wistar rats: preventive effect of picroliv.
Topics: Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Cinnamates; Drug Interactions; Enzymes; Glutathione; Glycogen; Glycosides; Lipid Peroxidation; Liver; Male; Plant Extracts; Rats; Rats, Wistar; Vanillic Acid | 2001 |
Hepatocurative effect of picroliv and silymarin against aflatoxin B1 induced hepatotoxicity in rats.
Topics: Aflatoxin B1; Animals; Chemical and Drug Induced Liver Injury; Cinnamates; Glycosides; Male; Rats; Silymarin; Vanillic Acid | 2000 |
Picroliv modulates the expression of insulin-like growth factor (IGF)-I, IGF-II and IGF-I receptor during hypoxia in rats.
Topics: Animals; Brain; Cinnamates; Gene Expression Regulation; Glycosides; Hypoxia; Immunohistochemistry; In Situ Hybridization; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Liver; Lung; Male; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Vanillic Acid | 1999 |
Inhibition of N-nitrosodiethylamine-induced hepatocarcinogenesis by Picroliv.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Antioxidants; Carcinogens; Cinnamates; Diethylnitrosamine; Glycosides; Hydroxyl Radical; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Organ Size; Plant Extracts; Rats; Rats, Wistar; Superoxides; Vanillic Acid | 2000 |
Protective effect of Picroliv, the active constituent of Picrorhiza kurroa, against chemical carcinogenesis in mice.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Carcinogens; Cinnamates; Croton Oil; Dermatologic Agents; Dose-Response Relationship, Drug; Glycosides; Male; Methylcholanthrene; Mice; Mice, Inbred BALB C; Models, Chemical; Neoplasms; Papilloma; Plant Extracts; Sarcoma; Time Factors; Vanillic Acid | 2001 |
Long term effect of aflatoxin B(1) on lipid peroxidation in rat liver and kidney: effect of picroliv and silymarin.
Topics: Aflatoxin B1; Animals; Antioxidants; Catalase; Cinnamates; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Glycosides; Kidney; Lipid Peroxidation; Liver; Male; Rats; Rats, Wistar; Silymarin; Superoxide Dismutase; Vanillic Acid | 2001 |
Picrorhiza kurroa. Monograph.
Topics: Asthma; Cinnamates; Glycosides; Humans; Liver Diseases; Medicine, Ayurvedic; Phytotherapy; Plant Extracts; Vanillic Acid | 2001 |
Picroliv modulates antioxidant status and down-regulates AP1 transcription factor after hemorrhage and resuscitation.
Topics: Animals; Antioxidants; Antiprotozoal Agents; Aspartate Aminotransferases; Blotting, Western; Cell Nucleus; Cinnamates; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Free Radicals; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glycosides; Hemorrhage; Lipid Peroxidation; Liver; Male; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Resuscitation; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Time Factors; Transcription Factor AP-1; Transcriptional Activation; Vanillic Acid | 2003 |
Modulation of carcinogenic response and antioxidant enzymes of rats administered with 1,2-dimethylhydrazine by Picroliv.
Topics: Administration, Oral; Animals; Bile Ducts; Bilirubin; Carcinogens; Catalase; Cell Division; Cinnamates; Dimethylhydrazines; gamma-Glutamyltransferase; Glutathione; Glycosides; Kidney; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; Male; Necrosis; Nucleolus Organizer Region; Plant Extracts; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vanillic Acid | 2003 |
Pattern profiling of the herbal preparation picroliv using liquid chromatography-tandem mass spectrometry.
Topics: Chromatography, Liquid; Cinnamates; Glycosides; Mass Spectrometry; Reproducibility of Results; Sensitivity and Specificity; Vanillic Acid | 2004 |
Efficacy of picroliv in combination with miltefosine, an orally effective antileishmanial drug against experimental visceral leishmaniasis.
Topics: Adjuvants, Immunologic; Animals; Antiprotozoal Agents; Biopsy; Cinnamates; Cricetinae; Drug Interactions; Drug Therapy, Combination; Female; Glycosides; Leishmania donovani; Leishmaniasis, Visceral; Male; Mesocricetus; Parasitemia; Phosphorylcholine; Picrorhiza; Vanillic Acid | 2005 |
Protective activity of picroliv on hepatic amoebiasis associated with carbon tetrachloride toxicity.
Topics: Animals; Antiprotozoal Agents; Carbon Tetrachloride; Cinnamates; Entamoeba histolytica; Glycosides; Liver; Liver Abscess, Amebic; Muridae; Phytotherapy; Picrorhiza; Plant Extracts; Vanillic Acid | 2005 |
Prevention of acute cadmium toxicity by Picroliv.
Topics: Animals; Cadmium Chloride; Chemical and Drug Induced Liver Injury; Cinnamates; Glycosides; Kidney; Liver; Liver Diseases; Male; Malondialdehyde; Oxidative Stress; Rats; Sodium-Potassium-Exchanging ATPase; Sulfhydryl Compounds; Testis; Vanillic Acid | 2005 |
Effect of Picroliv on cadmium-induced hepatic and renal damage in the rat.
Topics: Animals; Bile; Cadmium; Calcium; Cinnamates; Glycosides; Kidney; Lipid Peroxidation; Liver; Male; Membrane Fluidity; Metallothionein; Rats; Sodium-Potassium-Exchanging ATPase; Vanillic Acid | 2006 |
Picroliv accelerates epithelialization and angiogenesis in rat wounds.
Topics: Administration, Oral; Angiogenesis Inducing Agents; Animals; Aorta; Cinnamates; Endothelium, Vascular; Fibroblasts; Glycosides; Humans; Male; Neovascularization, Physiologic; Phytotherapy; Picrorhiza; Plant Extracts; Plant Roots; Rats; Rats, Sprague-Dawley; Umbilical Veins; Vanillic Acid; Vascular Endothelial Growth Factor A; Wound Healing | 2007 |
Protective effect of picroliv against hydrazine-induced hyperlipidemia and hepatic steatosis in rats.
Topics: Adipose Tissue; Animals; Cholesterol; Cinnamates; Disease Models, Animal; Fatty Acids, Nonesterified; Fatty Liver; Glycosides; Hydrazines; Hyperlipidemias; Hypolipidemic Agents; Lipid Metabolism; Liver; Male; Phospholipids; Rats; Rats, Wistar; Triglycerides; Vanillic Acid | 2007 |
Effect of Picroliv on cadmium induced testicular damage in rat.
Topics: Animals; Antiprotozoal Agents; Cadmium Chloride; Cinnamates; Glycosides; Lipid Peroxidation; Male; Metals, Heavy; Oxidative Stress; Rats; Testicular Diseases; Vanillic Acid | 2008 |
Immunomodulator effect of picroliv and its potential in treatment against resistant Plasmodium yoelii (MDR) infection in mice.
Topics: Animals; Antimalarials; B7-1 Antigen; B7-2 Antigen; Chloroquine; Cinnamates; Drug Resistance, Multiple; Drug Therapy, Combination; Female; Glycosides; Immunoglobulin G; Immunologic Factors; Lymphocyte Activation; Macrophages; Malaria; Mice; Mice, Inbred BALB C; Ovalbumin; Plasmodium yoelii; Reactive Oxygen Species; T-Lymphocytes; Time Factors; Up-Regulation; Vanillic Acid | 2008 |
Comparative efficacy of piperine, curcumin and picroliv against Cd immunotoxicity in mice.
Topics: Alkaloids; Animals; Apoptosis; B-Lymphocytes; Benzodioxoles; Cadmium Chloride; Caspase 3; Cell Survival; Cinnamates; Curcumin; DNA Damage; Glutathione; Glycosides; Interferon-gamma; Interleukin-2; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Oxidative Stress; Piperidines; Polyunsaturated Alkamides; Reactive Oxygen Species; Vanillic Acid | 2008 |
Modification of cysteine residue in p65 subunit of nuclear factor-kappaB (NF-kappaB) by picroliv suppresses NF-kappaB-regulated gene products and potentiates apoptosis.
Topics: Apoptosis; Blotting, Western; Cell Line, Tumor; Cinnamates; Cysteine; DNA, Neoplasm; Electrophoresis, Polyacrylamide Gel; Electrophoretic Mobility Shift Assay; Glycosides; Humans; Immunohistochemistry; In Situ Nick-End Labeling; NF-kappa B; Phosphorylation; Protein Transport; Tumor Necrosis Factor-alpha; Vanillic Acid | 2008 |
Inhibition of progression of erythroleukemia induced by Friend virus in BALB/c mice by natural products--berberine, curcumin and picroliv.
Topics: Animals; Antineoplastic Agents; Berberine; Biological Products; Cinnamates; Curcumin; Disease Progression; Friend murine leukemia virus; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glycosides; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Uric Acid; Vanillic Acid | 2008 |
Therapeutic efficacy of Picroliv in chronic cadmium toxicity.
Topics: Animals; Cadmium; Calcium; Cinnamates; Glycosides; Lipid Peroxidation; Liver; Male; Membrane Fluidity; Metallothionein; Plant Extracts; Rats; Sodium-Potassium-Exchanging ATPase; Vanillic Acid | 2009 |
Hepatoprotective activity of picroliv, curcumin and ellagic acid compared to silymarin on paracetamol induced liver toxicity in mice.
Topics: Acetaminophen; Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injury; Cinnamates; Curcumin; Ellagic Acid; Female; Glycosides; Lipid Peroxidation; Liver; Male; Mice; Oxidative Stress; Phytotherapy; Silymarin; Sleep; Vanillic Acid | 2009 |
Immunomodulatory effect of picroliv on the efficacy of paromomycin and miltefosine in combination in experimental visceral leishmaniasis.
Topics: Animals; Antiprotozoal Agents; Cell Proliferation; Cinnamates; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Glycosides; Leishmania donovani; Leishmaniasis, Visceral; Lymphocytes; Male; Mesocricetus; Paromomycin; Phagocytosis; Phosphorylcholine; Random Allocation; Reactive Nitrogen Species; Reactive Oxygen Species; Vanillic Acid | 2011 |
Antileishmanial efficacy of fluconazole and miltefosine in combination with an immunomodulator--picroliv.
Topics: Animals; Antiprotozoal Agents; Cinnamates; Cricetinae; Drug Therapy, Combination; Fluconazole; Glycosides; Hydrogen Peroxide; Immunity, Cellular; Leishmania donovani; Leishmaniasis, Visceral; Phagocytosis; Phosphorylcholine; Reactive Oxygen Species; Treatment Outcome; Vanillic Acid | 2011 |
Improved treatment of visceral leishmaniasis (kala-azar) by using combination of ketoconazole, miltefosine with an immunomodulator-Picroliv.
Topics: Animals; Antiprotozoal Agents; Cinnamates; Cricetinae; Disease Models, Animal; Drug Therapy, Combination; Female; Glycosides; Hydrogen Peroxide; Immunologic Factors; Ketoconazole; Leishmania donovani; Leishmaniasis, Visceral; Male; Phagocytosis; Phosphorylcholine; Reactive Nitrogen Species; Reactive Oxygen Species; Rodent Diseases; Treatment Outcome; Vanillic Acid | 2011 |
A Picrorhiza kurroa derivative, picroliv, attenuates the development of dextran-sulfate-sodium-induced colitis in mice.
Topics: Animals; Cinnamates; Colitis; Colon; Dextran Sulfate; Female; Glycosides; Mice; Mice, Inbred BALB C; Picrorhiza; Reverse Transcriptase Polymerase Chain Reaction; Vanillic Acid | 2012 |
Comparative pharmacokinetic profiles of picrosides I and II from kutkin, Picrorhiza kurroa extract and its formulation in rats.
Topics: Administration, Oral; Animals; Cinnamates; Glycosides; Iridoid Glucosides; Male; Picrorhiza; Plant Extracts; Plants, Medicinal; Rats; Rats, Sprague-Dawley; Vanillic Acid | 2013 |
Yield enhancement strategies for the production of picroliv from hairy root culture of Picrorhiza kurroa Royle ex Benth.
Topics: Agrobacterium; Bioreactors; Chromatography, High Pressure Liquid; Cinnamates; Culture Media; Culture Techniques; Glycosides; Hydrogen-Ion Concentration; Iridoid Glycosides; Picrorhiza; Plant Roots; Secondary Metabolism; Sucrose; Vanillic Acid; Vitamins | 2015 |
In vitro - In vivo metabolism and pharmacokinetics of picroside I and II using LC-ESI-MS method.
Topics: Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Cinnamates; Glycosides; Half-Life; Hepatocytes; Iridoid Glucosides; Male; Microsomes, Liver; Picrorhiza; Plant Roots; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Electrospray Ionization; Vanillic Acid | 2016 |
Development of nanoformulation of picroliv isolated from Picrorrhiza kurroa.
Topics: Cell Survival; Cinnamates; Drug Carriers; Glycosides; Humans; KB Cells; Lactic Acid; Nanoparticles; Picrorhiza; Polyesters; Polymers; Vanillic Acid | 2016 |
Protective effect of picroliv against lipopolysaccharide-induced cognitive dysfunction and neuroinflammation by attenuating TLR4/NFκB pathway.
Topics: Amyloid beta-Peptides; Animals; Astrocytes; Cinnamates; Cognitive Dysfunction; Glycosides; Inflammation; Lipopolysaccharides; Mice; Microglia; NF-kappa B; Toll-Like Receptor 4; Vanillic Acid | 2018 |
In vitro Effect of Chlorquine and Picroliv on Plasmodium Berghei Induced Alterations in the Activity of Adenosine Triphosphatase, Aryl Hyrocarbon Hydroxylase Enzymes and Malondialdehyde in Spleen Explant Culture.
Topics: Adenosine Triphosphatases; Animals; Cinnamates; Glycosides; Malondialdehyde; Mixed Function Oxygenases; Plant Extracts; Plasmodium berghei; Spleen; Vanillic Acid | 2021 |
Kutkin, iridoid glycosides enriched fraction of Picrorrhiza kurroa promotes insulin sensitivity and enhances glucose uptake by activating PI3K/Akt signaling in 3T3-L1 adipocytes.
Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; CCAAT-Enhancer-Binding Protein-alpha; Cinnamates; Diabetes Mellitus, Type 2; Glucose; Glucose Transporter Type 4; Glycosides; Insulin Resistance; Iridoid Glycosides; Mice; Phosphatidylinositol 3-Kinases; Picrorhiza; PPAR gamma; Proto-Oncogene Proteins c-akt; Triglycerides; Vanillic Acid; Wortmannin | 2022 |