vancomycin has been researched along with linezolid in 855 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 13 (1.52) | 18.2507 |
| 2000's | 311 (36.37) | 29.6817 |
| 2010's | 413 (48.30) | 24.3611 |
| 2020's | 118 (13.80) | 2.80 |
| Authors | Studies |
|---|---|
| Barbachyn, MR; Brickner, SJ; Ford, CW; Garmon, SA; Grega, KC; Hendges, SK; Hutchinson, DK; Manninen, PR; Toops, DS; Ulanowicz, DA; Zurenko, GE | 1 |
| Chu, DT; Katz, L; Plattner, JJ | 1 |
| Adams, WJ; Allwine, DA; Emmert, DE; Ford, CW; Friis, JM; Garmon, SA; Genin, MJ; Hamel, JC; Hester, JB; Hutchinson, DK; Schaadt, RD; Shobe, EM; Stapert, D; Yagi, BH; Zurenko, GE | 1 |
| Allwine, DA; Brickner, SJ; Ford, CW; Gleave, DM; Lovasz, KD; Manninen, PR; Rohrer, DC; Tucker, JA; Zurenko, GE | 1 |
| Cho, YS; Choi, JH; Choi, KI; Joo, HJ; Kim, BH; Kim, HY; Koh, HY; Pae, AN | 1 |
| Allwine, DA; Anderson, DJ; Barbachyn, MR; Emmert, DE; Ford, CW; Garmon, SA; Genin, MJ; Graber, DR; Grega, KC; Hamel, JC; Hester, JB; Hutchinson, DK; Morris, J; Reischer, RJ; Schaadt, RD; Stapert, D; Yagi, BH; Zurenko, GE | 1 |
| Airault, M; Benedetti, Y; Bonnefoy, A; Chatreaux, F; Demassey, J; Dupuis-Hamelin, C; Ferroud, D; Haesslein, JL; Iltis, A; Khider, J; Klich, M; Lachaud, S; Lassaigne, P; Laurin, P; Musicki, B; Periers, AM; Pierre, C; Tessot, N; Vicat, P | 1 |
| Charavaryamath, C; Das, J; Iqbal, J; Khera, MK; Kumar, MS; Mamidi, RN; Raheem, MA; Rajagopalan, R; Rao, BS; Sarnaik, H; Selvakumar, N; Srinivas, D | 1 |
| Inagaki, H; Kawakami, K; Kawato, HC; Matsuhashi, N; Miyauchi, RN; Miyauchi, S; Ohki, H; Takahashi, H; Takemura, M | 1 |
| Cha, JH; Chang, MH; Cho, YS; Kim, HY; Koh, HY; Lee, JS; Pae, AN | 1 |
| Chang, MH; Cho, YS; Chung, BY; Koh, HY; Lee, JS; Pae, AN | 1 |
| Das, J; Iqbal, J; Kandepu, S; Khera, MK; Kumar, MS; Raheem, MA; Rajagopalan, R; Rajale, TV; Selvakumar, N; Trehan, S | 1 |
| Hawser, S; Islam, K; Schneider, P | 1 |
| Bürli, RW; Chen, A; Duan, JX; Ge, Y; Gross, M; Hu, W; Iwamoto, M; Jiang, V; Johnson, KW; Jones, P; Kaizerman, JA; Moser, HE; Stanton, T; Touami, S; Truong, K | 1 |
| Inagaki, H; Takahashi, H; Takemura, M | 1 |
| Jefferson, EA; Migawa, MT; Osgood, SA; Ranken, R; Risen, LM; Robinson, DE; Rodgers, EL; Seth, PP; Swayze, EE | 1 |
| Arora, SK; Bhateja, P; Das, B; Malhotra, S; Mathur, T; Mehta, A; Pandya, M; Rao, AV; Rattan, A; Ray, A; Rudra, S; Saini, S; Shukla, S; Soni, A; Srinivas, AS; Yadav, A | 1 |
| Appelbaum, PC; Bhawsar, SB; Bozdogan, B; de Souza, NJ; Desai, VN; Deshpande, PK; Gupte, SV; Hooper, DC; Jacobs, MR; Jha, R; Khorakiwala, HF; Patel, MV; Shetty, N; Shukla, MC; Strahilevitz, J; Yeole, RD | 1 |
| Eldridge, GR; Garo, E; Goering, MG; Hough, GW; Hu, JF; O'Neil-Johnson, M | 1 |
| Das, J; Iqbal, J; Khera, MK; Selvakumar, N; Sitaram Kumar, M; Srinivas, D; Sunil Kumar, G; Trehan, S; Yadi Reddy, B | 1 |
| Cirioni, O; Della Vittoria, A; Giacometti, A; Kamysz, W; Licci, A; Okroj, M; Scalise, G; Silvestri, C | 1 |
| Duewelhenke, N; Eysel, P; Krut, O | 1 |
| Abbanat, D; Bush, K; Flamm, RK; Foleno, BD; Goldschmidt, RM; Macielag, MJ; Paget, SD; Webb, GC; Wira, E | 1 |
| Ali, AA; Phillips, OA; Samuel, SM; Udo, EE | 1 |
| Azhagan, AM; Das, J; Iqbal, J; Kumar, GS; Kumar, MS; Rajulu, GG; Selvakumar, N; Sharma, S; Trehan, S | 1 |
| Frank, KL; Patel, R; Piper, KE; Reichert, EJ | 1 |
| Cheung, CM; Chin, JN; Rybak, MJ; Savage, PB | 1 |
| Fiett, J; Gniadkowski, M; Grzesiowski, P; Hryniewicz, W; Izdebski, R; Sadowy, E | 1 |
| Cho, SH; Franzblau, SG; Hwang, CH; Pauli, GF; Wan, B; Warit, S | 1 |
| Hsueh, PR; Huang, YT; Liao, CH; Teng, LJ | 2 |
| Cirioni, O; Della Vittoria, A; Giacometti, A; Kamysz, W; Nadolski, P; Riva, A; Scalise, G; Silvestri, C; Łukasiak, J | 1 |
| Bradbury, BJ; Buechter, DD; Cheng, J; Deshpande, M; Hashimoto, A; Lucien, E; Marlor, CW; Nelson, DM; Ou, Y; Pais, GC; Podos, SD; Pucci, MJ; Song, Y; Thanassi, JA; Thoma, CL; Wang, Q; Wiles, JA | 1 |
| Badiou, C; Benito, Y; Bes, M; Boisset, S; Dumitrescu, O; Etienne, J; Lina, G; Reverdy, ME; Vandenesch, F | 1 |
| Bradbury, BJ; Buechter, DD; Cheng, J; Deshpande, M; Mushtaq, G; Podos, SD; Pucci, MJ; Thanassi, JA; Thoma, CL; Vigliotti, GA | 1 |
| Kurazono, M; Yamamoto, Y | 1 |
| Alder, JD; Li, T; Mortin, LI; Van Praagh, AD; Zhang, S; Zhang, XX | 1 |
| Chaiban, G; Dvorak, T; Hachem, R; Hanna, H; Jiang, Y; Raad, I; Reitzel, R; Sherertz, R | 1 |
| Entenza, JM; Leclercq, R; Moreillon, P; Wilson, WR | 1 |
| Chen, Y; Fan, H; Ji, R; Jiang, Z; Xu, G; Yang, Y; Zhang, S | 1 |
| Cho, JM; Chong, Y; Kim, CK; Kim, CM; Kim, JM; Lee, K; Ro, S; Yong, D; Yum, JH | 1 |
| Cheung, A; Götz, F; Herbert, S; Meehl, M | 1 |
| Chang, CL; Jeong, J; Jeong, SH; Jung, HJ; Kim, HR; Kim, S; Lee, EY; Lee, JN; Shin, JH | 1 |
| Dang, Z; Ji, R; Yang, Y; Zhang, S | 1 |
| Bugnon, D; Caillon, J; Ge, JY; Hamel, A; Jacqueline, C; Le Mabecque, V; Miègeville, AF; Potel, G | 1 |
| Jansen, WT; Milatovic, D; Verel, A; Verhoef, J | 1 |
| Bhateja, P; Das, B; Gujrati, A; Mathur, T; Pandya, M; Rattan, A; Rudra, S; Salman, M; Sangita, F; Singhal, S | 1 |
| Biswas, K; Crick, DC; Dhiman, R; Kurosu, M; Narayanasamy, P | 1 |
| Bryce, E; Gravel, D; Loeb, M; Louie, L; Matlow, A; McGeer, A; Mulvey, M; Ofner-Agostini, M; Simor, AE; Stuart, TL; Watt, C | 1 |
| Appelbaum, PC; Bogdanovich, T; Clark, C; Dewasse, B; Kosowska-Shick, K; McGhee, P | 1 |
| Bhateja, P; Cliffe, IA; Das, B; Malhotra, S; Mathur, T; Mehta, A; Pandya, M; Raja Rao, AV; Rattan, A; Rudra, S; Salman, M; Srinivas, AS; Yadav, A | 1 |
| Chen, Y; Fan, H; Ji, R; Jiang, Z; Yang, Y; Zhang, S; Zhong, D | 1 |
| Clark, NC; Hageman, J; McDonald, LC; McDougal, LK; Patel, JB; Zhu, W | 1 |
| Amarnath, PV; Chary, BC; Iqbal, J; Kandepu, S; Kumar, PK; Madhavi, T; Mallick, A; Praveena, K; Rajulu, GG; Reddy, KC; Reddy, KH; Selvakumar, N; Takhi, M | 1 |
| Fritsche, TR; Jones, RN; Sader, HS | 2 |
| Phillips, OA; Samuel, SM; Udo, EE | 1 |
| Baudry, PJ; DeCorby, M; Hoban, DJ; Johnson, J; Karlowsky, JA; Lagacé-Wiens, P; Laing, N; McCracken, M; Mulvey, MR; Nichol, KA; Tailor, F; Vashisht, R; Walkty, A; Weshnoweski, B; Wierzbowski, A; Zhanel, GG | 1 |
| Danese, P; DeVito, J; Franceschi, F; Lawrence, L; Sutcliffe, J | 1 |
| Calhoun, JH; Schmitt-Hoffmann, A; Shapiro, S; Thomas, JK; Yin, LY | 1 |
| Barbachyn, MR; Brickner, SJ; Hutchinson, DK; Manninen, PR | 1 |
| Castanheira, M; Deshpande, LM; DiPersio, J; Jones, RN; Mendes, RE; Saubolle, MA | 1 |
| Laohavaleeson, S; Nicolau, DP; Tessier, PR | 1 |
| Brickner, SJ; Duignan, J; Finegan, S; Girard, D; Huband, MD; Le, PT; Maloney, M; Schafer, J; Stone, GG; Wade, SK; Zaniewski, RP | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Benton, BM; Draghi, DC; Krause, KM; Pillar, C; Sahm, DF; Thornsberry, C | 1 |
| Benton, BM; Debabov, DV; Difuntorum, S; Krause, KM; Renelli, M; Wu, TX | 1 |
| Cheung, CM; Leonard, SN; Rybak, MJ | 1 |
| Amsler, KM; Bush, K; Davies, TA; Jacobs, MR; Shang, W | 1 |
| Biek, D; Ge, Y; Sahm, DF; Talbot, GH | 1 |
| Cui, L; Hiramatsu, K; Neoh, HM; Watanabe, Y | 1 |
| Edafiogho, IO; Phillips, OA; Rethish, B; Samuel, S; Udo, EE | 1 |
| del Pozo, JL; Mandrekar, JN; Patel, R; Rouse, MS; Sampedro, MF; Steckelberg, JM | 1 |
| Camargo, IL; Cui, L; Hiramatsu, K; Neoh, HM | 1 |
| Jacobus, NV; McDermott, LA; Snydman, DR | 1 |
| Brown-Driver, V; Finn, J; Pillar, CM; Poppe, S; Schaadt, R; Shaw, KJ; Shinabarger, D; Zurenko, G | 1 |
| Bradford, PA; Jones, CH; Mansour, TS; Petersen, PJ; Projan, SJ; Venkatesan, AM | 1 |
| Arhin, FF; Belley, A; Beveridge, T; Harris, R; McKay, G; Moeck, G; Neesham-Grenon, E; Parr, TR | 1 |
| Cui, L; Hiramatsu, K; Neoh, HM; Shoji, M | 1 |
| Bell, JM; Biedenbach, DJ; Jones, RN; Sader, HS; Turnidge, JD | 1 |
| Appelbaum, PC; Beachel, L; Caspers, P; Clark, C; Dewasse, B; Ednie, LM; Gaucher, B; Kosowska-Shick, K; Lin, G; McGhee, P; Mert, G; Shapiro, S; Smith, K | 1 |
| Denis, O; Nguyen, HA; Struelens, MJ; Theunis, A; Tulkens, PM; Van Bambeke, F; Vergison, A | 1 |
| Abbanat, D; Bush, K; Fernandez, J; Goldschmidt, R; Hilliard, JJ; Macielag, MJ; Melton, J | 1 |
| Daily, SJ; Smeltzer, MS; Spencer, HJ; Weiss, BD; Weiss, EC | 1 |
| Arhin, FF; Beaulieu, S; McKay, GA; Moeck, G; Parr, TR; Sarmiento, I | 1 |
| Abdel-Hamid, ME; Phillips, OA; Udo, EE; Varghese, R | 1 |
| Appelbaum, PC; Beachel, L; Clark, C; Dewasse, B; Kosowska-Shick, K; McGhee, P | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Mishra, NN; Sahu, DP; Shukla, PK; Varshney, V | 3 |
| Barrett, J; Colwell, L; Dropinski, JF; Farthing, AK; Hickey, EJ; Leavitt, PS; Liu, K; McCallum, C; Meinke, PT; Xu, L | 1 |
| Fisher, JF; Llarrull, LI; Mobashery, S | 1 |
| Hafkin, B; Hoban, DJ; Kaplan, N; Karlowsky, JA; Zhanel, GG | 1 |
| Schaadt, R; Shinabarger, D; Sweeney, D; Zurenko, G | 1 |
| Chen, H; Chen, M; Liu, Y; Ma, Y; Nichols, WW; Sun, W; Wang, H; Zhang, J; Zhao, C | 1 |
| Bolanos, M; Finegold, SM; Molitoris, DR; Sumannen, PH | 1 |
| Gaillard, JL; Jackson, M; McDonnell, G; Niederweis, M; Skovierová, H; Svetlíková, Z | 1 |
| Amaral, K; Dzink-Fox, J; Fischer, E; Goldovitz, J; Manni, K; Neckermann, G; Osborne, CS; Pecanka, R; Ryder, NS; Yu, D | 1 |
| Ariza, J; Cabellos, C; Cabo, J; Euba, G; Garrigós, C; Gudiol, F; Murillo, O; Pachón, ME; Verdaguer, R | 1 |
| Han, S; Hwang, JK; Lee, K; Rukayadi, Y; Yong, D | 1 |
| Hawser, S; Islam, K; Laue, H; Lociuro, S; Seguin, A; Valensise, T | 1 |
| Cheung, CM; Firestine, SM; Rybak, MJ; Vooturi, SK | 1 |
| Cai, Z; Fu, L; He, H; Jiang, Z; Liu, X; Yang, Y | 1 |
| Inagaki, H; Ito, M; Kawakami, K; Matsuhashi, N; Miyauchi, R; Ohki, H; Takahashi, H; Takemura, M | 1 |
| Banevicius, MA; Crandon, JL; Koomanachai, P; Nicolau, DP; Peng, L | 1 |
| Arhin, FF; Draghi, DC; Moeck, G; Parr, TR; Pillar, CM; Sahm, DF | 1 |
| Bowker, KE; Caspers, P; Gaucher, B; MacGowan, AP | 1 |
| Batard, E; Biek, D; Caillon, J; Ge, Y; Jacqueline, C; Le Mabecque, V; Miègeville, AF; Potel, G | 1 |
| Hilgers, M; Locke, JB; Shaw, KJ | 1 |
| Bonafede, M; Evans, A; Ferro, S; Harrington, S; Lodise, TP; Lubanski, P; Patel, N; Stellrecht, K | 1 |
| Adibpour, N; Khalaj, A; Rajabalian, S | 1 |
| Abbanat, D; Bush, K; Fernandez, J; Flamm, RK; Hilliard, JJ; Melton, JL; Santoro, CM; Zhang, W | 1 |
| Basuino, L; Bauer, D; Chambers, HF; Diep, BA; Tattevin, P | 1 |
| Kadlec, K; Schwarz, S | 1 |
| Cai, L; Gilbert, GL; Kong, F; Oftadeh, S; Xiao, M; Xu, X; Zhou, F | 1 |
| Chen, HC; King, CH; Lai, JF; Lauderdale, TL; Shiau, YR | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Betriu, C; Culebras, E; Gómez, M; López-Fabal, F; Morales, G; Picazo, JJ; Rodríguez-Avial, I | 1 |
| Bajaksouzian, S; Biek, D; Critchley, IA; Good, CE; Jacobs, MR; Jones, RN; Sader, HS; Windau, AR | 1 |
| Janechek, MJ; Jones, RN; Mendes, RE; Moet, GJ | 1 |
| Johnson, L; Pawlak, J; Saravolatz, L | 1 |
| Al-Qawasmeh, RA; Huesca, M; Lee, Y; Nedunuri, V; Peralta, R; Wright, J; Young, A | 1 |
| Duan, Y; Hu, W; Li, M; Qian, Y; Shi, W; Yang, L | 1 |
| Chen, FJ; Huang, IW; Lauderdale, TL; Lee, CH; Wang, MC | 1 |
| Cheung, CM; Leuthner, KD; Rybak, MJ; Vidaillac, C | 1 |
| Hogan, P; Huang, DB; Reisman, A | 1 |
| Dai, L; Huang, SY; Li, BB; Shen, JZ; Wang, MG; Wang, Y; Wu, CM; Xia, LN | 1 |
| Barrow, EW; Barrow, WW; Berlin, KD; Bourne, CR; Bourne, PC; Bunce, RA | 1 |
| Bavari, S; Bowlin, TL; Butler, MM; Moir, DT; Panchal, RG; Peet, NP; Shinabarger, DL; Williams, JD | 1 |
| Chan, JL; Cheung, GY; Joo, HS; Otto, M | 1 |
| Guo, Y; Hu, F; Jacoby, GA; Lin, D; Wang, F; Wang, M; Wu, S; Xu, X; Yan, G; Ye, X; Zhang, Y; Zhu, D | 1 |
| Hanaki, H; Hirose, T; Ichioka, M; Kobayashi, Y; Masuma, R; Matsui, H; Matsumoto, A; Nagai, K; Omura, S; Sunazuka, T; Takahashi, Y | 1 |
| G C, K; Hilgers, M; José Picazo, J; Locke, JB; Morales, G; Rahawi, S; Shaw, KJ; Stein, JL | 1 |
| Crandon, JL; Kuti, JL; Nicolau, DP | 1 |
| Baek, SY; Chae, SE; Cho, YL; Jeong, JW; Jung, SJ; Kim, YZ; Kwak, JH; Lee, HH; Lee, HS; Park, TK; Woo, SH | 1 |
| Brennan, OM; Coleman, DC; Ehricht, R; Monecke, S; Schwarz, S; Shore, AC; Slickers, P | 1 |
| Aubart, K; Duan, Y; Fang, Y; Hu, W; Ma, H; Shi, W; Yang, L; Zonis, R | 1 |
| Angehrn, P; Gmuender, H; Goetschi, E; Hebeisen, P; Hennig, M; Kuhn, B; Luebbers, T; Reindl, P; Ricklin, F; Schmitt-Hoffmann, A | 1 |
| Bradbury, BJ; Deshpande, M; Hashimoto, A; Kim, HY; Lucien, E; Nelson, DM; Pais, GC; Podos, SD; Pucci, MJ; Thanassi, JA; Wang, Q; Wiles, JA | 1 |
| Bradbury, BJ; Deshpande, M; Phadke, AS; Pucci, MJ; Thanassi, JA; Wiles, JA | 1 |
| Barnes, MH; Brown, NC; Butler, MM; Dvoskin, S; Gambino, JJ; Long, ZY; Wright, GE; Xu, WC; Zhi, CX | 1 |
| Alm, RA; Barthlow, H; Brassil, P; Breen, J; Ciaccio, P; Comita-Prevoir, J; Cronin, M; Ehmann, DE; Fisher, SL; Geng, B; Godfrey, AA; Goteti, K; McNulty, J; Newman, JV; Reck, F | 1 |
| Bonvin, Y; Briet, S; Denis, A; Desroy, N; Drocourt, E; Durant, L; Escaich, S; Faivre, F; Floquet, S; Genevard, JM; Gerusz, V; LeFralliec, G; Moreau, F; Oliveira, C; Oxoby, M; Peltier, L; Prouvensier, L; Raymond, C; Saccomani, M; Sam-Sambo, V; Soulama-Mouze, C; Vongsouthi, V; Walton, A | 1 |
| Kang, H; Kim, H; Nam, SJ; Rho, BJ; Wang, W | 1 |
| Baker, N; Bennett, JM; Chauhan, PK; Collins, I; Czaplewski, LG; Davies, DT; Gavade, M; Haydon, DJ; Kumar, D; Lancett, P; Macdonald, R; Macleod, L; Mahajan, A; Mitchell, JP; Nayal, N; Nayal, YN; Pitt, GR; Singh, M; Srivastava, A; Stokes, NR; Yadav, A | 1 |
| Gordeev, MF; Yuan, ZY | 1 |
| Axford, LC; Barker, S; Bennett, JM; Blair, M; Collins, I; Davies, DT; Ford, L; Gannon, CT; Haydon, DJ; Lancett, P; Logan, A; Lunniss, CJ; Morton, CJ; Offermann, DA; Palmer, JT; Pitt, GR; Rao, BN; Shukla, T; Singh, AK; Srivastava, A; Stokes, NR; Thomaides-Brears, HB; Yadav, A | 1 |
| Hu, W; Lv, F; Shi, W; Xing, D; Yang, L; Yang, S; Yang, Y; Zhao, Z | 1 |
| Dey, S; Dhawan, B; Kumar, S; Shekhar, S; Singh, K | 1 |
| Antunes, NT; Boudreau, MA; Chang, M; Ding, D; Lastochkin, E; Leemans, E; Lichtenwalter, K; Mobashery, S; O'Daniel, PI; Peng, Z; Pi, H; Schroeder, VA; Song, W; Spink, E; Suckow, MA; Testero, SA; Vakulenko, S; Wolter, WR | 1 |
| Banerjee, A; Chakrapani, H; Lahiri, S; Malwal, SR; Pardeshi, KA; Rangarajan, R | 1 |
| An, IH; Guevara-Zuluaga, S; Pierce, JG; Shymanska, NV | 1 |
| Creemer, CN; Dai, M; Davis, DC; Kyei-Baffour, K; Mohammad, H; Seleem, MN; Younis, W | 1 |
| Gea, KD; Miller, SJ; Wadzinski, TJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Steenbergen, J; Tanaka, SK; Villano, S | 1 |
| Abdelghany, TM; Fayed, E; Mayhoub, AS; Mohammad, H; Seleem, MN; Yahia, E | 1 |
| Choi, H; Giri, AG; Hahn, D; Kang, H; Kim, H; Lee, J; Nam, SJ; Patil, RS; Sung, Y; Wang, W; Won, DH | 1 |
| Brozovic, A; Dowson, CG; Gazvoda, M; Košmrlj, J; Lloyd, A; Osmak, M; Proud, C; Roper, DI; Vajs, J | 1 |
| Chen, L; Cooper, B; Cushman, M; Mayhoub, A; Mohammad, H; Oldfield, E; Peters, CE; Pogliano, J; Pogliano, K; Seleem, MN; Younis, W; Zhang, J | 1 |
| Abd Rabo Moustafa, MM; Abdelghany, TM; Eissa, IH; Elshafeey, A; Mayhoub, AS; Mohammad, H; Qassem, OA; Seleem, MN; Younis, W | 1 |
| Alverson, JB; Decato, D; Hoody, J; Klepacki, D; McGrath, K; Priestley, ND; Stierle, AA; Stierle, DB | 1 |
| Abulkhair, HS; Cooper, B; Eid, I; Elsebaei, MM; Hagras, M; Hegazy, YA; Mayhoub, AS; Mohammad, H; Peters, CE; Pogliano, J; Pogliano, K; Seleem, MN | 1 |
| Chen, F; Chen, W; Hu, L; Lan, L; Li, B; Li, J; Li, X; Lin, D; Liu, W; Liu, Y; Lu, Y; Mao, F; Ni, S; Qiu, X; Wang, M; Wei, H; Xu, Y; Zheng, X; Zhu, J | 1 |
| Abdelghany, TM; Elkabbany, AH; Ghiaty, A; Hagras, M; Hegazy, YA; Mayhoub, AS; Mohammad, H; Seleem, MN | 1 |
| Deshmukh, MS; Jain, N | 1 |
| Chen, F; Chen, W; Lan, L; Li, B; Li, J; Liu, Y; Mao, F; Ni, S; Wei, H; Zhu, J | 1 |
| Chen, F; Hu, L; Lan, L; Li, B; Li, J; Mao, F; Ni, S; Qiu, X; Wang, M; Wei, H; Zheng, X; Zhu, J | 1 |
| Chen, K; Chen, LJ; Cheng, XJ; Fu, SH; Lian, M; Peng, AH; Tang, H; Wang, ZL; Wu, B; Ye, HY; Zhang, Q | 1 |
| Javed, K; Malik, ZM; Sattigeri, JA; Shafi, S; Shamim, M; Siddiqui, AM; Singhal, S | 1 |
| Chen, F; Hu, L; Lan, L; Li, B; Li, J; Li, X; Ling, D; Liu, W; Liu, Y; Mao, F; Ni, S; Qiu, X; Wang, M; Wei, H; Xu, Y; Zheng, X; Zhu, J | 1 |
| Abutaleb, NS; Bayoumi, A; Ghiaty, A; Hagras, M; Kotb, A; Mayhoub, AS; Mohammad, H; Seleem, MA; Seleem, MN | 1 |
| Abouelhassan, Y; Garrison, AT; Huigens, RW; Jin, S; Kallifidas, D; Kim, YS; Luesch, H; Tan, H | 1 |
| Abouelhassan, Y; Basak, A; Huigens, RW; Jin, S; Kim, YS; Norwood, VM | 1 |
| Abutaleb, NS; Dayal, N; Mohammad, H; Naclerio, GA; Opoku-Temeng, C; Seleem, MN; Sintim, HO | 1 |
| Bai, PY; Chu, WC; Cui, DY; Hua, YG; Qin, SS; Yang, QQ; Yang, Y; Zhang, E | 1 |
| Abouelhassan, Y; Garrison, AT; Huigens Iii, RW; Nguyen, TJ; Yang, H; Yousaf, HH | 1 |
| Ameryckx, A; Frédérick, R; Joris, B; Leimanis, S; Pochet, L; Poupaert, JH; Thabault, L; Van Bambeke, F; Wouters, J | 1 |
| Eswaran, S; Narayanan, S; Shivarudraiah, P; Shruthi, TG; Subramanian, S | 1 |
| Deng, Y; Duan, Y; Huang, Y; Kang, D; Li, Y; Liu, X; Qiu, L; Shen, B; Su, M; Wen, Z | 1 |
| Dai, M; Kyei-Baffour, K; Mohammad, H; Seleem, MN | 1 |
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| Bhando, T; Borrillo, L; Brown, ED; Coombes, BK; Farha, MA; Fragis, M; Jardine, E; Johnson, JW; Klobucar, K; MacKinnon, MR; Magolan, J; Nkonge, B; Tsai, CN | 1 |
| Das, AK; Dudeja, M; Kohli, S; Ray, P | 1 |
| De Vito, D; Fruscio, G; Garrisi, VM; Hall, GG; Laforgia, M; Nardulli, P; Quarta, A; Ruggiero, R; Scacco, S | 1 |
| Babić, G; Krečak, I; Skelin, M | 1 |
| Martinez, AI; Santos, CAQ; Trick, WE; Tseng, M; Varughese, CA; Won, SY; Zhang, H | 1 |
| Pawlak, J; Saravolatz, LD | 1 |
| Habib, A; Qadir, A | 1 |
| Fujii, S | 1 |
| Han, Y; Shen, M; Tang, M; Xu, C; Yao, Z; Zeng, W; Zhang, X; Zheng, X; Zhou, T | 1 |
| Jia, L; Jiang, Y; Li, X; Peng, Z; Wang, Y | 1 |
| Chang, SC; Chen, YC; Chuang, YC; Huang, SH; Huang, ST; Lin, CY; Wang, JT; Yang, JL | 1 |
| Ernst, G; Kot, L; Scolari, M; Trovato, D | 1 |
| Fujikawa, T; Hasegawa, D; Kasai, M; Kosaka, Y; Mizuno, S; Uemura, S | 1 |
| Liu, X; Tian, Z; Wang, M | 1 |
| Bryan, E; Ferrer-González, E; Fujita, J; Kaul, M; LaVoie, EJ; Mark, L; Matsumura, H; Pilch, DS; Sagong, HY | 1 |
| Bennardo, F; Colosimo, M; De Sarro, G; Fortunato, L; Gallelli, L; Giudice, A; Palleria, C | 1 |
| Hasegawa, S; Imai, M; Izumisawa, T; Saito, D; Takahashi, N; Yamasaki, M | 1 |
| Canale, V; Czekajewska, J; Empel, J; Karczewska, E; Kasza, P; Klesiewicz, K; Kuziak, A; Niemiec, D; Papież, M; Pękala, E; Piska, K; Tomczak, M; Witek, K; Zajdel, P | 1 |
| AbdAlhafiz, AI; Aboshanab, KM; Aboulwafa, MM; Elleboudy, NS; Hassouna, NA | 1 |
| Dinh, HC; Ho, DS; Ho, DT; Le, TD; Ngo, HT; Nguyen, CD | 1 |
| Abbott, IJ; Cairns, KA; Dooley, MJ; Peel, TN; Peleg, AY; Udy, AA | 1 |
| AlSaifi, M; Azzam, A; Elagezy, FK; Elsisi, S; Khaled, H; Mohsen, M; Mosa, M; Refaey, N | 1 |
| Cai, H; Cao, Q; Chen, Y; Deng, H; Deng, J; Hao, J; He, L; Huang, Y; Jing, C; Lin, A; Wang, C; Wu, X; Xu, H; Yang, J; Yu, H; Zhang, T | 1 |
| Arriaga-García, FJ; Medellín-Garibay, SE; Milán-Segovia, RDC; Pérez-González, LF; Rodríguez-Báez, AS; Romano-Moreno, S; Velarde-Salcedo, R | 1 |
| Ding, L; Ding, X; Duan, L; Liu, C; Mao, J; Shi, L; Sun, J; Tang, L; Wang, W; Wu, D; Xie, L; Xu, J; Yang, Z; Zhou, Q | 1 |
| Akhtar, MF; Akhtar, MM; Alqasoumi, AA; Alshammari, MS; Altaf, U; Altowayan, WM; Batool, N; Godman, B; Haseeb, A; Imam, MT; Raees, F; Saleem, Z | 1 |
| Li, H; Li, Z; Lyu, C; Shen, J; Wang, X; Zhang, L | 1 |
| García-Angulo, VA; Paredes-Amaya, CC; Ulloa, MT | 1 |
| Junlin, Y; Lingzhu, LI; Luo Guangying, -; Meng Huaqing, -; Zha Zhuhong, - | 1 |
| Guo, Q; Huang, K; Lin, B; Liu, Y; Ren, H; Song, H; Zhou, R | 1 |
| An, Z; Feng, X; Yang, H; Zhang, Y | 1 |
| Chen, H; Liu, S; Tang, M; Xu, C; Yao, Z; Zhang, X; Zhao, D; Zhou, C; Zhou, T | 1 |
| Hashimoto, T; Hiramatsu, K; Itoh, H; Iwao, M; Morinaga, Y; Tanaka, R; Tatsuta, R | 1 |
101 review(s) available for vancomycin and linezolid
| Article | Year |
|---|---|
New directions in antibacterial research.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Molecular Sequence Data; Molecular Structure | 1996 |
Linezolid (ZYVOX), the first member of a completely new class of antibacterial agents for treatment of serious gram-positive infections.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones | 2008 |
Molecular basis and phenotype of methicillin resistance in Staphylococcus aureus and insights into new beta-lactams that meet the challenge.
Topics: Anti-Bacterial Agents; beta-Lactams; Cell Wall; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Penicillin-Binding Proteins; Peptide Synthases; Staphylococcus aureus | 2009 |
New potent antibacterial oxazolidinone (MRX-I) with an improved class safety profile.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bone Marrow Cells; Clinical Trials, Phase I as Topic; Drug Design; Drug Resistance, Bacterial; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Monoamine Oxidase Inhibitors; Oxazolidinones; Pyridones; Sepsis | 2014 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Discovery, pharmacology, and clinical profile of omadacycline, a novel aminomethylcycline antibiotic.
Topics: Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Drug Discovery; Humans; Microbial Sensitivity Tests; Molecular Conformation; Tetracyclines | 2016 |
Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019.
Topics: Biological Products; Drug Discovery; History, 20th Century; History, 21st Century; Molecular Structure; Pharmaceutical Preparations | 2020 |
1,2,3-Triazole-containing hybrids with potential antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA).
Topics: Anti-Bacterial Agents; Drug Design; Methicillin-Resistant Staphylococcus aureus; Triazoles | 2020 |
Synthetic access to thiolane-based therapeutics and biological activity studies.
Topics: Alkaloids; Anti-Infective Agents; Antineoplastic Agents; Bacteria; Biological Products; Cell Survival; Fungi; Humans; Sesquiterpenes; Sulfhydryl Compounds | 2021 |
Antibiotics for gram-positive bacterial infections. Vancomycin, teicoplanin, quinupristin/dalfopristin, and linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Oxazoles; Oxazolidinones; Teicoplanin; Vancomycin; Virginiamycin | 2000 |
Use of anti-infective agents during lactation: Part 1--Beta-lactam antibiotics, vancomycin, quinupristin-dalfopristin, and linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactams; Drug Therapy, Combination; Female; Humans; Lactation; Linezolid; Milk, Human; Mothers; Oxazolidinones; Vancomycin; Virginiamycin | 2000 |
Microbial drug resistance and the roles of the new antibiotics.
Topics: Acetamides; Anti-Infective Agents; Atovaquone; Aza Compounds; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Enterococcus; Fluoroquinolones; Gatifloxacin; Humans; Linezolid; Methicillin Resistance; Moxifloxacin; Naphthoquinones; Oxazolidinones; Proguanil; Pseudomonas aeruginosa; Quinolines; Staphylococcus aureus; Streptococcus pneumoniae; Vancomycin; Vancomycin Resistance; Virginiamycin | 2001 |
Gram-positive bacterial resistance. A challenge for the next millennium.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Therapy, Combination; Enterococcus; Gram-Positive Bacteria; Humans; Linezolid; Oxazolidinones; Staphylococcus aureus; Vancomycin; Virginiamycin | 2002 |
[Oxazolidinones and glycopeptides].
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Biotransformation; Cell Wall; Drug Resistance, Multiple, Bacterial; Gram-Positive Bacterial Infections; Histamine Release; Humans; Linezolid; Molecular Structure; Oxazolidinones; Peptidoglycan; Pneumonia, Bacterial; Protein Synthesis Inhibitors; Staphylococcal Infections; Teicoplanin; Vancomycin | 2003 |
Antimicrobial resistance among gram-positive organisms in the intensive care unit.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Community-Acquired Infections; Drug Resistance, Microbial; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Intensive Care Units; Linezolid; Methicillin Resistance; Oxazolidinones; Staphylococcus aureus; Treatment Outcome; United States; Vancomycin; Virginiamycin | 2003 |
Coagulase-negative staphylococcal disease: emerging therapies for the neonatal and pediatric patient.
Topics: Acetamides; Anti-Infective Agents; Child; Child, Preschool; Coagulase; Drug Resistance, Bacterial; Humans; Infant; Infant, Newborn; Linezolid; Oxazolidinones; Staphylococcal Infections; Staphylococcal Vaccines; Staphylococcus; Treatment Outcome; Vancomycin | 2004 |
Alternatives for MRSA treatment in the pediatric patient.
Topics: Acetamides; Adolescent; Adult; Anti-Infective Agents; Child; Child, Preschool; Humans; Infant; Infant, Newborn; Linezolid; Methicillin Resistance; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2004 |
Severe staphylococcal knee arthritis responding favourably to linezolid, after glycopeptide-rifampicin failure: a case report and literature review.
Topics: Acetamides; Anti-Bacterial Agents; Arthritis, Infectious; Drug Therapy, Combination; HIV Infections; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Rifampin; Staphylococcal Infections; Teicoplanin; Vancomycin | 2005 |
Linezolid versus vancomycin for Staphylococcus aureus bacteraemia: pooled analysis of randomized studies.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Bacteremia; Female; Humans; Linezolid; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Oxazolidinones; Randomized Controlled Trials as Topic; Retrospective Studies; Staphylococcal Infections; Staphylococcus aureus; Survival Analysis; Treatment Outcome; Vancomycin | 2005 |
Antibiotic resistance in Staphylococcus aureus and its relevance in therapy.
Topics: Acetamides; Anti-Bacterial Agents; beta-Lactams; Clinical Trials as Topic; Drug Resistance, Bacterial; Glycopeptides; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Penicillins; Staphylococcal Infections; Staphylococcus aureus; Vaccination; Vaccines, DNA; Vancomycin; Vancomycin Resistance | 2005 |
Update on linezolid: the first oxazolidinone antibiotic.
Topics: Acetamides; Administration, Oral; Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Positive Cocci; Humans; Injections, Intravenous; Linezolid; Oxazolidinones; Pneumonia, Bacterial; Practice Guidelines as Topic; Product Surveillance, Postmarketing; Randomized Controlled Trials as Topic; Skin Diseases, Bacterial; Soft Tissue Infections; Teicoplanin; Vancomycin | 2005 |
Treatment approaches for community-acquired methicillin-resistant Staphylococcus aureus infections.
Topics: Acetamides; Anti-Bacterial Agents; Community-Acquired Infections; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2005 |
Dalbavancin: a review for dermatologists.
Topics: Acetamides; Adult; Animals; Catheterization; Clinical Trials, Phase III as Topic; Cross Infection; Double-Blind Method; Drug Resistance, Multiple, Bacterial; Enterococcus; Female; Fever; Gram-Positive Bacterial Infections; Headache; Humans; Linezolid; Male; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Rabbits; Randomized Controlled Trials as Topic; Skin Diseases, Bacterial; Staphylococcal Skin Infections; Teicoplanin; Treatment Outcome; Vancomycin | 2006 |
Pharmacologic treatment options for nosocomial pneumonia involving methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Cross Infection; Humans; Linezolid; MEDLINE; Methicillin Resistance; Oxazolidinones; Pneumonia, Staphylococcal; Staphylococcus aureus; Vancomycin | 2007 |
Antimicrobial symposium. Part VIII. Glycopeptides, oxazolidinones, and lipopeptides.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Daptomycin; Drug Resistance, Microbial; Glycopeptides; Humans; Linezolid; Molecular Structure; Oxazolidinones; Peptides, Cyclic; Vancomycin | 2007 |
[Therapeutic perspectives of linezolid in the management of infections due to multiresistant Gram-positive pathogens].
Topics: Acetamides; Administration, Oral; Anti-Infective Agents; Daptomycin; Drug Resistance, Multiple, Bacterial; Enterococcus; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Injections, Intravenous; Linezolid; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Practice Guidelines as Topic; Staphylococcus aureus; Streptococcus pneumoniae; Teicoplanin; Tigecycline; Time Factors; Vancomycin; Virginiamycin | 2007 |
Combating the growing problem of methicillin-resistant Staphylococcus aureus: do the newer antibiotics represent a better alternative to vancomycin?
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Linezolid; Methicillin Resistance; Minocycline; Oxazolidinones; Staphylococcus aureus; Tigecycline; Vancomycin; Virginiamycin | 2007 |
Treatment of infections caused by resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Bacterial; Humans; Linezolid; Methicillin Resistance; Minocycline; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Tigecycline; Vancomycin; Virginiamycin | 2007 |
Optimizing therapy for MRSA pneumonia.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Daptomycin; Humans; Linezolid; Methicillin Resistance; Minocycline; Oxazolidinones; Pneumonia, Bacterial; Staphylococcus aureus; Tigecycline; Vancomycin | 2007 |
Optimizing therapy for methicillin-resistant Staphylococcus aureus bacteremia.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Daptomycin; Endocarditis; Equipment Contamination; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Staphylococcus aureus; Vancomycin | 2007 |
Optimizing therapy for vancomycin-resistant enterococci (VRE).
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Cross Infection; Drug Resistance, Microbial; Enterococcus; Gram-Positive Bacterial Infections; Humans; Linezolid; Oxazolidinones; Vancomycin | 2007 |
Pharmacoeconomics of linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Clinical Trials as Topic; Costs and Cost Analysis; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Models, Econometric; Oxazolidinones; Quality of Life; Staphylococcus aureus; Teicoplanin; Vancomycin | 2008 |
Pneumonia caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Community-Acquired Infections; Cross Infection; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Pneumonia; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2008 |
Methicillin-resistant Staphylococcus aureus: an update for the dermatologist, Part 3: Clinical management.
Topics: Acetamides; Algorithms; Anti-Bacterial Agents; Clindamycin; Community-Acquired Infections; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Staphylococcal Skin Infections; Staphylococcus aureus; Tetracycline; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2008 |
Antimicrobial agents in treatment of MRSA infections.
Topics: Acetamides; Anti-Bacterial Agents; Cephalosporins; Clindamycin; Community-Acquired Infections; Daptomycin; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fluoroquinolones; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Minocycline; Oxazolidinones; Staphylococcal Infections; Teicoplanin; Tetracyclines; Tigecycline; Trimethoprim, Sulfamethoxazole Drug Combination; United States; Vancomycin | 2008 |
Cost-effectiveness analysis of linezolid vs. vancomycin in treating methicillin-resistant Staphylococcus aureus complicated skin and soft tissue infections using a decision analytic model.
Topics: Acetamides; Cost-Benefit Analysis; Decision Support Techniques; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Risk Factors; Soft Tissue Infections; Staphylococcal Infections; Staphylococcal Skin Infections; Vancomycin | 2009 |
Treatment options for nosocomial pneumonia due to MRSA.
Topics: Acetamides; Anti-Bacterial Agents; Cross Infection; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Pneumonia, Ventilator-Associated; Vancomycin | 2009 |
Linezolid versus vancomycin for MRSA skin and soft tissue infections (systematic review and meta-analysis).
Topics: Acetamides; Anti-Infective Agents; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Randomized Controlled Trials as Topic; Soft Tissue Infections; Staphylococcal Infections; Staphylococcal Skin Infections; Vancomycin | 2009 |
Linezolid versus vancomycin for the treatment of gram-positive bacterial infections: meta-analysis of randomised controlled trials.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Drug-Related Side Effects and Adverse Reactions; Gram-Positive Bacterial Infections; Humans; Linezolid; Oxazolidinones; Pneumonia, Bacterial; Randomized Controlled Trials as Topic; Skin Diseases, Bacterial; Soft Tissue Infections; Treatment Outcome; Vancomycin | 2010 |
Efficacy and safety of linezolid in methicillin-resistant Staphylococcus aureus (MRSA) complicated skin and soft tissue infection (cSSTI): a meta-analysis.
Topics: Acetamides; Aged; Anti-Infective Agents; Drug Resistance, Bacterial; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Soft Tissue Infections; Staphylococcal Infections; Staphylococcal Skin Infections; Treatment Outcome; Vancomycin | 2010 |
The importance of tissue penetration in achieving successful antimicrobial treatment of nosocomial pneumonia and complicated skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus: vancomycin and linezolid.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Cross Infection; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Pneumonia, Bacterial; Skin Diseases, Bacterial; Soft Tissue Infections; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2010 |
Management of methicillin-resistant Staphylococcus aureus pneumonia.
Topics: Acetamides; Anti-Bacterial Agents; Community-Acquired Infections; Cross Infection; Humans; Incidence; Infusions, Intravenous; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Vancomycin | 2010 |
Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: a systematic review and meta-analysis.
Topics: Acetamides; Anti-Bacterial Agents; Cross Infection; Education, Medical, Continuing; Humans; Linezolid; Oxazolidinones; Pneumonia, Bacterial; Prospective Studies; Randomized Controlled Trials as Topic; Renal Insufficiency; Teicoplanin; Thrombocytopenia; Vancomycin | 2010 |
[Lipopeptides and oxazolidinones--novel antibiotics in MRSA infection treatment].
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Staphylococcal Infections; Vancomycin | 2010 |
Nosocomial methicillin-resistant Staphylococcus aureus (MRSA) pneumonia: linezolid or vancomycin? - Comparison of pharmacology and clinical efficacy.
Topics: Acetamides; Anti-Bacterial Agents; Cross Infection; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Bacterial; Vancomycin | 2010 |
Treatment of complicated skin and soft-tissue infections caused by resistant bacteria: value of linezolid, tigecycline, daptomycin and vancomycin.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Microbial; Humans; Linezolid; Minocycline; Oxazolidinones; Skin Diseases; Soft Tissue Infections; Tigecycline; Vancomycin | 2010 |
[Linezolid versus vancomycin in the treatment of pneumonia caused by Gram-positive cocci: meta-analysis of randomised controlled trials].
Topics: Acetamides; Anti-Bacterial Agents; Cross Infection; Gram-Positive Cocci; Humans; Linezolid; Oxazolidinones; Pneumonia, Pneumococcal; Randomized Controlled Trials as Topic; Vancomycin | 2010 |
Antibiotic dosing during sustained low-efficiency dialysis: special considerations in adult critically ill patients.
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Critical Care; Daptomycin; Echinocandins; Fluoroquinolones; Humans; Linezolid; Oxazolidinones; Peritoneal Dialysis, Continuous Ambulatory; Renal Dialysis; Renal Insufficiency; Vancomycin | 2011 |
Management of serious meticillin-resistant Staphylococcus aureus infections: what are the limits?
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Daptomycin; Endocarditis, Bacterial; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Pneumonia, Bacterial; Staphylococcal Infections; Teicoplanin; Tigecycline; Treatment Outcome; Vancomycin | 2011 |
[Update of antimicrobial resistance in Gram-positive microorganisms].
Topics: Acetamides; Anti-Bacterial Agents; Community-Acquired Infections; Cross Infection; Daptomycin; Drug Resistance, Microbial; Drug Resistance, Multiple, Bacterial; Enterococcus; Europe; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Staphylococcal Infections; United States; Vancomycin | 2010 |
Clinical activity of anti-Gram-positive agents against methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2011 |
Management of antibiotic-resistant infection in the newborn.
Topics: Acetamides; Anti-Bacterial Agents; Carbapenems; Colistin; Daptomycin; Drug Resistance, Bacterial; Gram-Negative Bacterial Infections; Humans; Infant, Newborn; Linezolid; Oxazolidinones; Vancomycin | 2011 |
Nosocomial MRSA pneumonia: data from recent clinical trials.
Topics: Acetamides; Anti-Infective Agents; Bronchoalveolar Lavage Fluid; Bronchoscopy; Cross Infection; DNA, Bacterial; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Pneumonia, Ventilator-Associated; Polymerase Chain Reaction; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Vancomycin | 2011 |
[Staphylococcus aureus and antibiotic resistance].
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Bacterial; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Minocycline; Oxazolidinones; Protein Synthesis Inhibitors; Staphylococcal Infections; Teicoplanin; Tigecycline; Vancomycin; Vancomycin Resistance; Virginiamycin | 2011 |
Simplifying the treatment of acute bacterial bone and joint infections in children.
Topics: Acetamides; Acute Disease; Anti-Bacterial Agents; Arthritis, Infectious; Bone and Bones; C-Reactive Protein; Child; Child, Preschool; Clindamycin; Drug Administration Schedule; Finland; Humans; Joints; Kingella kingae; Linezolid; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Neisseriaceae Infections; Osteomyelitis; Oxazolidinones; Prospective Studies; Randomized Controlled Trials as Topic; Staphylococcal Infections; Vancomycin | 2011 |
Linezolid and vancomycin in treatment of lower-extremity complicated skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus in patients with and without vascular disease.
Topics: Acetamides; Administration, Oral; Aged; Anti-Bacterial Agents; Female; Humans; Infusions, Intravenous; Linezolid; Lower Extremity; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Randomized Controlled Trials as Topic; Staphylococcal Skin Infections; Treatment Outcome; Vancomycin; Vascular Diseases | 2012 |
[The cutting-edge of medicine anti-MRSA agents; how to select and how to use].
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Cross Infection; Daptomycin; Dibekacin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Staphylococcal Infections; Teicoplanin; Vancomycin | 2012 |
Pharmacotherapy for methicillin-resistant Staphylococcus aureus nosocomial pneumonia.
Topics: Acetamides; Anti-Bacterial Agents; Cost-Benefit Analysis; Cross Infection; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Pneumonia, Staphylococcal; Vancomycin | 2012 |
Cost-effectiveness of linezolid in methicillin-resistant Staphylococcus aureus skin and skin structure infections.
Topics: Acetamides; Administration, Oral; Anti-Bacterial Agents; Cost-Benefit Analysis; Economics, Pharmaceutical; Health Care Costs; Hospitalization; Humans; Length of Stay; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Soft Tissue Infections; Staphylococcal Skin Infections; Vancomycin | 2012 |
The efficacy and safety of linezolid and glycopeptides in the treatment of Staphylococcus aureus infections.
Topics: Acetamides; Anti-Bacterial Agents; Glycopeptides; Humans; Linezolid; Odds Ratio; Oxazolidinones; PubMed; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Treatment Outcome; Vancomycin | 2013 |
Linezolid versus vancomycin for meticillin-resistant Staphylococcus aureus infection: a meta-analysis of randomised controlled trials.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Incidence; Kidney; Kidney Function Tests; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Randomized Controlled Trials as Topic; Staphylococcal Infections; Treatment Outcome; Vancomycin; Young Adult | 2013 |
Linezolid versus vancomycin or teicoplanin for nosocomial pneumonia: meta-analysis of randomised controlled trials.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Cross Infection; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia; Randomized Controlled Trials as Topic; Staphylococcal Infections; Teicoplanin; Vancomycin | 2013 |
[Guidelines for antimicrobial treatment of the infection by Staphylococcus aureus].
Topics: Acetamides; Aminoglycosides; Animals; Anti-Bacterial Agents; beta-Lactams; Clindamycin; Daptomycin; Disease Models, Animal; Fluoroquinolones; Fosfomycin; Guidelines as Topic; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Tetracyclines; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2013 |
Linezolid versus vancomycin for skin and soft tissue infections.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Drug Eruptions; Humans; Length of Stay; Linezolid; Oxazolidinones; Pruritus; Randomized Controlled Trials as Topic; Skin Diseases, Bacterial; Soft Tissue Infections; Thrombocytopenia; Vancomycin | 2013 |
Antibiotic therapy for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections in surgical wounds.
Topics: Acetamides; Administration, Oral; Anti-Bacterial Agents; Humans; Injections, Intravenous; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Randomized Controlled Trials as Topic; Staphylococcal Infections; Surgical Wound Infection; Vancomycin | 2013 |
Systematic review and meta-analysis of linezolid versus daptomycin for treatment of vancomycin-resistant enterococcal bacteremia.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Bacteremia; Daptomycin; Drug Combinations; Enterococcus; Humans; Linezolid; Middle Aged; Oxazolidinones; Retrospective Studies; Survival Analysis; Treatment Outcome; Vancomycin; Vancomycin Resistance | 2014 |
European perspective and update on the management of nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus after more than 10 years of experience with linezolid.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Cross Infection; Disease Models, Animal; Europe; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Pneumonia, Ventilator-Associated; Practice Guidelines as Topic; Risk Factors; Vancomycin | 2014 |
[Therapeutic Drug Monitoring of antiinfectives in intensive care medicine].
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; beta-Lactams; Biological Availability; Dose-Response Relationship, Drug; Drug Monitoring; Drug Therapy, Combination; Fluoroquinolones; Guideline Adherence; Humans; Intensive Care Units; Linezolid; Metabolic Clearance Rate; Microbial Sensitivity Tests; Oxazolidinones; Sepsis; Shock, Septic; Teicoplanin; Vancomycin | 2014 |
What's new in the treatment of serious MRSA infection?
Topics: Acetamides; Anti-Bacterial Agents; Cephalosporins; Cost-Benefit Analysis; Drug Administration Routes; Drug Therapy, Combination; Glycopeptides; Humans; Linezolid; Lipoglycopeptides; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Severity of Illness Index; Skin Diseases, Bacterial; Staphylococcal Infections; Tetrazoles; Vancomycin | 2014 |
Clinical management of Staphylococcus aureus bacteremia: a review.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Bacteremia; Daptomycin; Drug Therapy, Combination; Echocardiography, Transesophageal; Endocarditis, Bacterial; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2014 |
[Antibiotics for treatment of infections by methicillin-resistant Staphylococcus aureus (MRSA)].
Topics: Acetamides; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Evidence-Based Medicine; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Treatment Outcome; Vancomycin | 2014 |
Optimizing therapy for vancomycin-resistant enterococcal bacteremia in children.
Topics: Acetamides; Adolescent; Child; Child, Preschool; Daptomycin; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Oxazolidinones; Risk Factors; Treatment Outcome; Vancomycin; Vancomycin-Resistant Enterococci; Virginiamycin | 2014 |
Vancomycin-resistant enterococcal bacteremia pharmacotherapy.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Daptomycin; Gram-Positive Bacterial Infections; Humans; Linezolid; Oxazolidinones; Vancomycin; Vancomycin-Resistant Enterococci; Virginiamycin | 2015 |
Linezolid versus vancomycin for the treatment of suspected methicillin-resistant Staphylococcus aureus nosocomial pneumonia: a systematic review employing meta-analysis.
Topics: Acetamides; Anti-Bacterial Agents; Cross Infection; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia; Randomized Controlled Trials as Topic; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2015 |
Daptomycin versus linezolid for treatment of vancomycin-resistant enterococcal bacteremia: systematic review and meta-analysis.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Daptomycin; Humans; Linezolid; Oxazolidinones; Retrospective Studies; Treatment Outcome; Vancomycin; Vancomycin Resistance; Vancomycin-Resistant Enterococci | 2014 |
Novel pandemic influenza A (H1N1) and community-associated methicillin-resistant Staphylococcus aureus pneumonia.
Topics: Anti-Bacterial Agents; Community-Acquired Infections; Drug Resistance, Bacterial; Early Diagnosis; Humans; Influenza A Virus, H1N1 Subtype; Influenza, Human; Linezolid; Methicillin-Resistant Staphylococcus aureus; Pandemics; Pneumonia, Bacterial; Pneumonia, Staphylococcal; Vancomycin | 2015 |
Antibiotic management of methicillin-resistant Staphylococcus aureus--associated acute pulmonary exacerbations in cystic fibrosis.
Topics: Acetamides; Anti-Bacterial Agents; Cystic Fibrosis; Humans; Linezolid; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Staphylococcal Infections; Vancomycin | 2015 |
What is the best therapeutic approach to methicillin-resistant Staphylococcus aureus pneumonia?
Topics: Acetamides; Anti-Bacterial Agents; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Treatment Outcome; Vancomycin | 2015 |
Clinical implications of vancomycin heteroresistant and intermediately susceptible Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Daptomycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Humans; Linezolid; Risk Factors; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2015 |
Comparative efficacy of antibiotics for the treatment of acute bacterial skin and skin structure infections (ABSSSI): a systematic review and network meta-analysis.
Topics: Acute Disease; Anti-Bacterial Agents; Glycopeptides; Humans; Linezolid; Lipoglycopeptides; Skin Diseases, Bacterial; Vancomycin | 2015 |
MRSA in Croatia: prevalence and management.
Topics: Animals; Anti-Bacterial Agents; Carrier State; Cattle; Croatia; Daptomycin; Humans; Linezolid; Livestock; Methicillin-Resistant Staphylococcus aureus; Minocycline; Prevalence; Soft Tissue Infections; Staphylococcal Infections; Staphylococcal Skin Infections; Swine; Teicoplanin; Tigecycline; Vancomycin; Zoonoses | 2016 |
Linezolid versus vancomycin for skin and soft tissue infections.
Topics: Adult; Anti-Bacterial Agents; Drug Eruptions; Humans; Length of Stay; Linezolid; Pruritus; Randomized Controlled Trials as Topic; Skin Diseases, Bacterial; Soft Tissue Infections; Thrombocytopenia; Vancomycin | 2016 |
Acute bacterial skin and skin structure infections in internal medicine wards: old and new drugs.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Carbapenems; Ceftaroline; Cephalosporins; Daptomycin; Female; Fluoroquinolones; Glycopeptides; Hospitalization; Humans; Iatrogenic Disease; Internal Medicine; Linezolid; Lipoglycopeptides; Male; Minocycline; Oxazolidinones; Skin Diseases, Infectious; Soft Tissue Infections; Teicoplanin; Tigecycline; Vancomycin | 2016 |
Treatment Options for Persistent Coagulase Negative Staphylococcal Bacteremia in Neonates.
Topics: Anti-Infective Agents; Daptomycin; Dose-Response Relationship, Drug; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Linezolid; Retrospective Studies; Rifampin; Sepsis; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2016 |
Methicillin-resistant Staphylococcus aureus infections: A review of the currently available treatment options.
Topics: Anti-Bacterial Agents; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Staphylococcal Infections; Vancomycin | 2016 |
Vancomycin and the Risk of AKI: A Systematic Review and Meta-Analysis.
Topics: Acute Kidney Injury; Administration, Intravenous; Anti-Bacterial Agents; Humans; Linezolid; Risk Factors; Vancomycin | 2016 |
Systematic review and network meta-analysis of tedizolid for the treatment of acute bacterial skin and skin structure infections caused by MRSA.
Topics: Anti-Bacterial Agents; Bayes Theorem; Ceftaroline; Cephalosporins; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Organophosphates; Oxazoles; Oxazolidinones; Skin Diseases, Bacterial; Staphylococcal Infections; Tetrazoles; Vancomycin | 2017 |
Role of vancomycin in the treatment of bacteraemia and meningitis caused by Elizabethkingia meningoseptica.
Topics: Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Disk Diffusion Antimicrobial Tests; Drug Synergism; Drug Therapy, Combination; Flavobacteriaceae; Flavobacteriaceae Infections; Humans; Immunocompromised Host; Infant, Low Birth Weight; Infant, Newborn; Linezolid; Meningitis, Bacterial; Rifampin; Treatment Outcome; Vancomycin | 2017 |
Linezolid vs. vancomycin in treatment of methicillin-resistant staphylococcus aureus infections: a meta-analysis.
Topics: Anti-Bacterial Agents; Clinical Trials as Topic; Databases, Factual; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Odds Ratio; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2017 |
Efficacy and safety of linezolid compared with other treatments for skin and soft tissue infections: a meta-analysis.
Topics: Anti-Bacterial Agents; Humans; Linezolid; Skin; Soft Tissue Infections; Staphylococcal Infections; Vancomycin | 2018 |
Is there still a role for vancomycin in skin and soft-tissue infections?
Topics: Anti-Bacterial Agents; Drug Utilization; Drug-Related Side Effects and Adverse Reactions; Glycopeptides; Humans; Linezolid; Skin Diseases, Infectious; Soft Tissue Infections; Treatment Outcome; Vancomycin | 2018 |
State of the art in cystic fibrosis pharmacology-Optimization of antimicrobials in the treatment of cystic fibrosis pulmonary exacerbations: I. Anti-methicillin-resistant Staphylococcus aureus (MRSA) antibiotics.
Topics: Aminoglycosides; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Ciprofloxacin; Clindamycin; Cystic Fibrosis; Humans; Linezolid; Lipoglycopeptides; Methicillin; Methicillin-Resistant Staphylococcus aureus; Rifampin; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2020 |
Efficacy and safety of daptomycin versus linezolid treatment in patients with vancomycin-resistant enterococcal bacteraemia: An updated systematic review and meta-analysis.
Topics: Anti-Bacterial Agents; Bacteremia; Daptomycin; Humans; Linezolid; Vancomycin | 2020 |
Vancomycin-resistant Enterococcus faecium pneumonia in a uremic patient on hemodialysis: a case report and review of the literature.
Topics: Anti-Bacterial Agents; Community-Acquired Infections; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Pneumonia, Bacterial; Renal Dialysis; Treatment Outcome; Uremia; Vancomycin; Vancomycin Resistance; Vancomycin-Resistant Enterococci | 2020 |
Acute Bacterial Skin and Skin-Structure Infections, efficacy of Dalbavancin: a systematic review and meta-analysis.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Humans; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Penicillins; Skin Diseases, Bacterial; Staphylococcus aureus; Vancomycin | 2022 |
Meta-analysis of vancomycin versus linezolid in pneumonia with proven methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia; Randomized Controlled Trials as Topic; Vancomycin | 2021 |
The mysteries of target site concentrations of antibiotics in bone and joint infections: what is known? A narrative review.
Topics: Anti-Bacterial Agents; Cefazolin; Cefuroxime; Ciprofloxacin; Humans; Linezolid; Microbial Sensitivity Tests; Vancomycin | 2022 |
A 600 mg of fixed-dose linezolid in renally impaired patients versus 15 mg/kg intermittent dose-optimized vancomycin in renally non-impaired patients: A single centre retrospective analysis for adult patients with hospital-acquired pneumonia due to methic
Topics: Adult; Anti-Bacterial Agents; Creatinine; Cross Infection; Healthcare-Associated Pneumonia; Hospitals; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Pneumonia, Staphylococcal; Renal Insufficiency; Retrospective Studies; Treatment Outcome; Vancomycin | 2023 |
Therapeutics for Vancomycin-Resistant Enterococcal Bloodstream Infections.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Gram-Positive Bacterial Infections; Humans; Linezolid; Sepsis; Vancomycin; Vancomycin-Resistant Enterococci | 2023 |
Epidemiology of clinically isolated methicillin-resistant Staphylococcus aureus (MRSA) and its susceptibility to linezolid and vancomycin in Egypt: a systematic review with meta-analysis.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cefoxitin; Egypt; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Staphylococcal Infections; Vancomycin | 2023 |
Fierce poison to others: the phenomenon of bacterial dependence on antibiotics.
Topics: Anti-Bacterial Agents; Bacteria; Colistin; Drug Resistance, Bacterial; Linezolid; Microbial Sensitivity Tests; Poisons; Vancomycin | 2023 |
51 trial(s) available for vancomycin and linezolid
| Article | Year |
|---|---|
In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections.
Topics: Anti-Bacterial Agents; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Skin Diseases, Bacterial; Staphylococcus | 2008 |
Clinical outcomes by methicillin-resistant Staphylococcus aureus staphylococcal cassette chromosome mec type: isolates recovered from a phase IV clinical trial of linezolid and vancomycin for complicated skin and skin structure infections.
Topics: Acetamides; Anti-Bacterial Agents; Chromosomes, Bacterial; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Skin Diseases; Staphylococcal Infections; Vancomycin | 2010 |
Linezolid (PNU-100766) versus vancomycin in the treatment of hospitalized patients with nosocomial pneumonia: a randomized, double-blind, multicenter study.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Aztreonam; Cross Infection; Double-Blind Method; Drug Resistance, Microbial; Drug Therapy, Combination; Gram-Positive Bacteria; Hospitalization; Humans; Linezolid; Male; Middle Aged; Monobactams; Oxazolidinones; Pneumonia; Safety; Time Factors; Treatment Outcome; Vancomycin | 2001 |
Comparison of length of hospital stay for patients with known or suspected methicillin-resistant Staphylococcus species infections treated with linezolid or vancomycin: a randomized, multicenter trial.
Topics: Acetamides; Administration, Oral; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Female; Humans; Injections, Intravenous; Length of Stay; Linezolid; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2001 |
Approaches to analysis of length of hospital stay related to antibiotic therapy in a randomized clinical trial: linezolid versus vancomycin for treatment of known or suspected methicillin-resistant Staphylococcus species infections.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Clinical Trials, Phase III as Topic; Costs and Cost Analysis; Female; Health Care Costs; Humans; Length of Stay; Linezolid; Male; Methicillin Resistance; Middle Aged; Models, Statistical; Multicenter Studies as Topic; Oxazolidinones; Randomized Controlled Trials as Topic; Retrospective Studies; Staphylococcal Infections; Time Factors; Vancomycin | 2002 |
Linezolid versus vancomycin for the treatment of methicillin-resistant Staphylococcus aureus infections.
Topics: Acetamides; Anti-Bacterial Agents; Female; Humans; Linezolid; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin | 2002 |
Effects of linezolid on hospital length of stay compared with vancomycin in treatment of methicillin-resistant Staphylococcus infections. An application of multivariate survival analysis.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Drug Administration Routes; Hospitalization; Humans; Length of Stay; Linezolid; Methicillin Resistance; Middle Aged; Multivariate Analysis; Oxazolidinones; Proportional Hazards Models; Staphylococcal Infections; Staphylococcus; Survival Analysis; Treatment Outcome; Vancomycin | 2002 |
Effect of linezolid versus vancomycin on length of hospital stay in patients with complicated skin and soft tissue infections caused by known or suspected methicillin-resistant staphylococci: results from a randomized clinical trial.
Topics: Acetamides; Administration, Oral; Aged; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Length of Stay; Linezolid; Male; Methicillin Resistance; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Probability; Prognosis; Severity of Illness Index; Skin Diseases, Bacterial; Staphylococcus aureus; Treatment Outcome; Vancomycin; Wound Infection | 2003 |
Continuation of a randomized, double-blind, multicenter study of linezolid versus vancomycin in the treatment of patients with nosocomial pneumonia.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Cross Infection; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Pneumonia, Bacterial; Vancomycin | 2003 |
Linezolid versus vancomycin for treatment of resistant Gram-positive infections in children.
Topics: Acetamides; Bacteremia; Child; Child, Preschool; Confidence Intervals; Cross Infection; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Multiple; Female; Follow-Up Studies; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Infant; Infant, Newborn; Latin America; Linezolid; Male; Microbial Sensitivity Tests; Oxazolidinones; Probability; Severity of Illness Index; Treatment Outcome; United States; Vancomycin | 2003 |
Linezolid versus vancomycin in the treatment of known or suspected resistant gram-positive infections in neonates.
Topics: Acetamides; Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Female; Gram-Positive Bacterial Infections; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Infusions, Intravenous; Linezolid; Male; Oxazolidinones; Treatment Outcome; Vancomycin | 2003 |
Linezolid for the treatment of children with bacteremia or nosocomial pneumonia caused by resistant gram-positive bacterial pathogens.
Topics: Acetamides; Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Child; Child, Preschool; Cross Infection; Drug Resistance, Microbial; Female; Gram-Positive Bacterial Infections; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Linezolid; Male; Oxazolidinones; Pneumonia, Bacterial; Treatment Outcome; Vancomycin | 2003 |
Linezolid for the treatment of complicated skin and skin structure infections in children.
Topics: Acetamides; Administration, Oral; Age Factors; Anti-Bacterial Agents; Anti-Infective Agents; Child; Child, Preschool; Female; Gram-Positive Bacterial Infections; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Linezolid; Male; Oxazolidinones; Skin Diseases, Bacterial; Treatment Outcome; Vancomycin | 2003 |
Hematologic effects of linezolid in young children.
Topics: Acetamides; Administration, Oral; Age Factors; Anemia; Anti-Bacterial Agents; Anti-Infective Agents; Child; Child, Preschool; Female; Gram-Positive Bacterial Infections; Hemoglobins; Humans; Infant; Infant, Newborn; Infusions, Intravenous; Linezolid; Male; Neutropenia; Oxazolidinones; Thrombocytopenia; Vancomycin | 2003 |
Linezolid does not increase the risk of thrombocytopenia in patients with nosocomial pneumonia: comparative analysis of linezolid and vancomycin use.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Cross Infection; Double-Blind Method; Female; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Pneumonia, Bacterial; Prospective Studies; Thrombocytopenia; Vancomycin | 2003 |
Linezolid eradicates MRSA better than vancomycin from surgical-site infections.
Topics: Acetamides; Adult; Aged; Analysis of Variance; Chi-Square Distribution; Female; Follow-Up Studies; Humans; International Cooperation; Linezolid; Male; Methicillin Resistance; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Probability; Risk Assessment; Severity of Illness Index; Single-Blind Method; Staphylococcal Infections; Staphylococcus aureus; Surgical Wound Infection; Treatment Outcome; Vancomycin; Wound Healing | 2004 |
Clinical and economic outcomes of oral linezolid versus intravenous vancomycin in the treatment of MRSA-complicated, lower-extremity skin and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Administration, Oral; Adult; Aged; Cost-Benefit Analysis; Female; Follow-Up Studies; Humans; Infusions, Intravenous; Linezolid; Lower Extremity; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Probability; Reference Values; Severity of Illness Index; Single-Blind Method; Skin Diseases, Infectious; Soft Tissue Infections; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; United States; Vancomycin | 2005 |
Linezolid versus vancomycin in treatment of complicated skin and soft tissue infections.
Topics: Acetamides; Adult; Aged; Anti-Infective Agents; Female; Humans; Internationality; Linezolid; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Skin Diseases, Bacterial; Soft Tissue Infections; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin | 2005 |
Linezolid reduces length of stay and duration of intravenous treatment compared with vancomycin for complicated skin and soft tissue infections due to suspected or proven methicillin-resistant Staphylococcus aureus (MRSA).
Topics: Acetamides; Administration, Oral; Adolescent; Adult; Aged; Americas; Anti-Bacterial Agents; Anti-Infective Agents; Asia; Europe; Female; Humans; Injections, Intravenous; Length of Stay; Linezolid; Male; Methicillin; Methicillin Resistance; Middle Aged; New Zealand; Oxazolidinones; Soft Tissue Infections; Staphylococcal Infections; Staphylococcal Skin Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin | 2005 |
Efficacy and safety of linezolid compared with vancomycin in a randomized, double-blind study of febrile neutropenic patients with cancer.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Double-Blind Method; Female; Fever; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Middle Aged; Neoplasms; Neutropenia; Oxazolidinones; Vancomycin | 2006 |
Impact of linezolid on economic outcomes and determinants of cost in a clinical trial evaluating patients with MRSA complicated skin and soft-tissue infections.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Aztreonam; Clinical Trials as Topic; Cost-Benefit Analysis; Delivery of Health Care; Drug Costs; Drug Therapy, Combination; Female; Humans; Injections, Intravenous; Linezolid; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Prospective Studies; Regression Analysis; Skin Diseases, Infectious; Streptococcal Infections; Treatment Outcome; Vancomycin | 2006 |
Cost-effectiveness of linezolid and vancomycin in the treatment of surgical site infections.
Topics: Acetamides; Anti-Infective Agents; Cost-Benefit Analysis; Decision Trees; Female; Hospitalization; Humans; Linezolid; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Retrospective Studies; Staphylococcal Infections; Surgical Wound Infection; Treatment Outcome; Vancomycin | 2007 |
Larval therapy: a novel treatment in eliminating methicillin-resistant Staphylococcus aureus from diabetic foot ulcers.
Topics: Acetamides; Aged; Animals; Diabetic Foot; Diabetic Neuropathies; Foot Ulcer; Humans; Larva; Linezolid; Methicillin Resistance; Middle Aged; Oxazolidinones; Patient Selection; Reproducibility of Results; Staphylococcus aureus; Vancomycin | 2007 |
Linezolid versus vancomycin for the treatment of infections caused by methicillin-resistant Staphylococcus aureus in Japan.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Female; Humans; Japan; Linezolid; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2007 |
Larger vancomycin doses (at least four grams per day) are associated with an increased incidence of nephrotoxicity.
Topics: Acetamides; Anti-Bacterial Agents; Cohort Studies; Creatinine; Dose-Response Relationship, Drug; Female; Humans; Incidence; Kidney; Kidney Diseases; Linezolid; Male; Middle Aged; Oxazolidinones; Vancomycin | 2008 |
Linezolid for the treatment of infections caused by Gram-positive pathogens in China.
Topics: Acetamides; Adolescent; Adult; Aged; Anti-Bacterial Agents; China; Cross Infection; Double-Blind Method; Female; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Pneumonia, Bacterial; Skin Diseases, Bacterial; Soft Tissue Infections; Treatment Outcome; Vancomycin | 2008 |
Efficacy and safety of tigecycline compared with vancomycin or linezolid for treatment of serious infections with methicillin-resistant Staphylococcus aureus or vancomycin-resistant enterococci: a Phase 3, multicentre, double-blind, randomized study.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Cross Infection; Double-Blind Method; Enterococcus; Female; Gram-Positive Bacterial Infections; Hospitalization; Humans; Linezolid; Male; Methicillin Resistance; Middle Aged; Minocycline; Oxazolidinones; Staphylococcus aureus; Tigecycline; Treatment Outcome; Vancomycin; Vancomycin Resistance | 2008 |
Early microbiological response to linezolid vs vancomycin in ventilator-associated pneumonia due to methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Female; Follow-Up Studies; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Pneumonia, Ventilator-Associated; Prospective Studies; Staphylococcal Infections; Time Factors; Treatment Outcome; Vancomycin | 2008 |
Complicated skin and skin-structure infections and catheter-related bloodstream infections: noninferiority of linezolid in a phase 3 study.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Cross Infection; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Skin Diseases, Bacterial; Vancomycin | 2009 |
Salvage treatment for persistent methicillin-resistant Staphylococcus aureus bacteremia: efficacy of linezolid with or without carbapenem.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Aminoglycosides; Anti-Bacterial Agents; Bacteremia; Carbapenems; Drug Therapy, Combination; Humans; Korea; Linezolid; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Salvage Therapy; Staphylococcal Infections; Treatment Outcome; Vancomycin; Young Adult | 2009 |
Characterization of baseline methicillin-resistant Staphylococcus aureus isolates recovered from phase IV clinical trial for linezolid.
Topics: Acetamides; Americas; Anti-Bacterial Agents; Bacterial Typing Techniques; Cluster Analysis; DNA Fingerprinting; Drug Resistance, Bacterial; Europe; Genotype; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Epidemiology; Oxazolidinones; Soft Tissue Infections; South Africa; Staphylococcal Skin Infections; Vancomycin | 2010 |
Efficacy and safety of linezolid versus vancomycin for the treatment of complicated skin and soft-tissue infections proven to be caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Chi-Square Distribution; Female; Humans; Length of Stay; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Prospective Studies; Soft Tissue Infections; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2010 |
Linezolid more efficacious than vancomycin to eradicate infecting organism in critically ill patients with Gram-positive infections.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Critical Care; Critical Illness; Female; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Intensive Care Units; Length of Stay; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Prospective Studies; Treatment Outcome; Vancomycin | 2010 |
The impact of linezolid and vancomycin treatment on local signs and symptoms of inflammation among pediatric patients with complicated skin and skin structure infections.
Topics: Acetamides; Anti-Bacterial Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; Gram-Positive Bacterial Infections; Hospitalization; Humans; Infant; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pediatrics; Skin Diseases, Bacterial; Treatment Outcome; Vancomycin | 2011 |
Linezolid versus vancomycin antibiotic lock solution for the prevention of nontunneled catheter-related blood stream infections in hemodialysis patients: a prospective randomized study.
Topics: Acetamides; Aged; Aged, 80 and over; Anti-Infective Agents; Bacteremia; Catheter-Related Infections; Catheters, Indwelling; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Kidney Failure, Chronic; Linezolid; Male; Middle Aged; Oxazolidinones; Prospective Studies; Renal Dialysis; RNA, Ribosomal, 23S; Treatment Outcome; Vancomycin | 2012 |
Characterization of methicillin-resistant Staphylococcus aureus strains recovered from a phase IV clinical trial for linezolid versus vancomycin for treatment of nosocomial pneumonia.
Topics: Acetamides; Anti-Bacterial Agents; Cluster Analysis; Cross Infection; DNA, Bacterial; Double-Blind Method; Electrophoresis, Gel, Pulsed-Field; Genotype; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Epidemiology; Multilocus Sequence Typing; Oxazolidinones; Pneumonia, Staphylococcal; Prospective Studies; Staphylococcal Protein A; United States; Vancomycin | 2012 |
The impact of linezolid versus vancomycin on surgical interventions for complicated skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Chi-Square Distribution; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Multivariate Analysis; Oxazolidinones; Prospective Studies; Staphylococcal Skin Infections; Vancomycin | 2013 |
Impact of weight on treatment efficacy and safety in complicated skin and skin structure infections and nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Body Weight; Cross Infection; Dose-Response Relationship, Drug; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Pneumonia, Staphylococcal; Staphylococcal Skin Infections; Treatment Outcome; Vancomycin | 2013 |
The ZEPHyR study: a randomized comparison of linezolid and vancomycin for MRSA pneumonia.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Cross Infection; Double-Blind Method; Humans; Kidney Diseases; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Prospective Studies; Survival Analysis; Treatment Outcome; Vancomycin | 2013 |
A comparison of microbiology and demographics among patients with healthcare-associated, hospital-acquired, and ventilator-associated pneumonia: a retrospective analysis of 1184 patients from a large, international study.
Topics: Acetamides; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteria; Cross Infection; Demography; Female; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Pneumonia, Ventilator-Associated; Retrospective Studies; Risk Factors; Vancomycin | 2013 |
Impact of patient characteristics and infection type on clinical outcomes of patients who received linezolid or vancomycin for complicated skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus: a pooled data analysis.
Topics: Acetamides; Aged; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Prospective Studies; Skin; Staphylococcal Skin Infections; Treatment Outcome; Vancomycin | 2014 |
Once-weekly dalbavancin versus daily conventional therapy for skin infection.
Topics: Acetamides; Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Double-Blind Method; Drug Administration Schedule; Female; Humans; Infusions, Intravenous; Linezolid; Male; Middle Aged; Oxazolidinones; Skin Diseases, Bacterial; Teicoplanin; Vancomycin; Young Adult | 2014 |
Modeling the economic impact of linezolid versus vancomycin in confirmed nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Cost-Benefit Analysis; Cross Infection; Double-Blind Method; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Models, Economic; Oxazolidinones; Pneumonia, Staphylococcal; Prospective Studies; Vancomycin | 2014 |
Health economic evaluation of patients treated for nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus: secondary analysis of a multicenter randomized clinical trial of vancomycin and linezolid.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cost-Benefit Analysis; Cross Infection; Double-Blind Method; Drug Costs; Female; Health Resources; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Pneumonia, Staphylococcal; Pneumonia, Ventilator-Associated; Renal Dialysis; Renal Insufficiency; Treatment Outcome; Vancomycin | 2014 |
Predictors of Clinical Success in the Treatment of Patients with Methicillin-Resistant Staphylococcus aureus (MRSA) Nosocomial Pneumonia (NP).
Topics: Adult; Aged; Aged, 80 and over; Cross Infection; Double-Blind Method; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Pneumonia, Staphylococcal; Vancomycin | 2015 |
Linezolid Versus Vancomycin in the Empiric Treatment of Nosocomial Pneumonia: A Cost-Utility Analysis Incorporating Results from the ZEPHyR Trial.
Topics: Anti-Bacterial Agents; Computer Simulation; Cost Savings; Cost-Benefit Analysis; Cross Infection; Decision Support Techniques; Drug Costs; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Models, Economic; Monte Carlo Method; Pneumonia, Staphylococcal; Probability; Prospective Studies; Quality-Adjusted Life Years; Treatment Outcome; Uncertainty; Vancomycin | 2015 |
Economic evaluation among Chinese patients with nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus and treated with linezolid or vancomycin: a secondary, post-hoc analysis based on a Phase 4 clinical trial study.
Topics: Adult; Aged; Anti-Bacterial Agents; China; Comorbidity; Cost-Benefit Analysis; Cross Infection; Double-Blind Method; Female; Health Services; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Models, Econometric; Pneumonia, Bacterial; Renal Insufficiency; Severity of Illness Index; Socioeconomic Factors; Staphylococcal Infections; Vancomycin | 2016 |
A randomized, double-blind, Phase 2 study to evaluate subjective and objective outcomes in patients with acute bacterial skin and skin structure infections treated with delafloxacin, linezolid or vancomycin.
Topics: Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Double-Blind Method; Female; Fluoroquinolones; Humans; Linezolid; Male; Middle Aged; Skin Diseases, Bacterial; Treatment Outcome; Vancomycin; Young Adult | 2016 |
The effect of diabetes mellitus on outcomes of patients with nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus: data from a prospective double-blind clinical trial comparing treatment with linezolid versus vancomycin.
Topics: Adult; Aged; Anti-Bacterial Agents; Diabetes Mellitus; Double-Blind Method; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Pneumonia, Staphylococcal; Prospective Studies; Retrospective Studies; Treatment Outcome; Vancomycin | 2016 |
Clinical outcomes of linezolid and vancomycin in patients with nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus stratified by baseline renal function: a retrospective, cohort analysis.
Topics: Aged; Anti-Bacterial Agents; Cohort Studies; Cross Infection; Female; Humans; Kidney Diseases; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Pneumonia, Bacterial; Retrospective Studies; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2017 |
Rapid Detection of Methicillin-Resistant Staphylococcus aureus in BAL: A Pilot Randomized Controlled Trial.
Topics: Anti-Bacterial Agents; Antimicrobial Stewardship; Bacteriological Techniques; Bronchoalveolar Lavage Fluid; Diagnostic Tests, Routine; Drug Resistance, Microbial; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Pilot Projects; Pneumonia, Staphylococcal; Reproducibility of Results; Vancomycin | 2019 |
703 other study(ies) available for vancomycin and linezolid
| Article | Year |
|---|---|
Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections.
Topics: Acetamides; Animals; Anti-Infective Agents; Dogs; Drug Resistance, Microbial; Drug Resistance, Multiple; Female; Linezolid; Magnetic Resonance Spectroscopy; Mass Spectrometry; Mice; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Rats | 1996 |
Nitrogen-carbon-linked (azolylphenyl)oxazolidinones with potent antibacterial activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Colony Count, Microbial; Haemophilus influenzae; Inhibitory Concentration 50; Injections, Intravenous; Male; Mice; Moraxella catarrhalis; Oxazoles; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Structure-Activity Relationship | 1998 |
Synthesis and antibacterial activity of [6,5,5] and [6,6,5] tricyclic fused oxazolidinones.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Indicators and Reagents; Mice; Microbial Sensitivity Tests; Models, Molecular; Molecular Conformation; Molecular Structure; Oxazoles; Structure-Activity Relationship | 1998 |
Synthesis and in vitro activity of new oxazolidinone antibacterial agents having substituted isoxazoles.
Topics: Anti-Bacterial Agents; Gram-Positive Bacteria; Isoxazoles; Microbial Sensitivity Tests; Oxazoles | 1999 |
Substituent effects on the antibacterial activity of nitrogen-carbon-linked (azolylphenyl)oxazolidinones with expanded activity against the fastidious gram-negative organisms Haemophilus influenzae and Moraxella catarrhalis.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Azoles; Haemophilus influenzae; Humans; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Moraxella catarrhalis; Oxazoles; Structure-Activity Relationship | 2000 |
Improved antibacterial activities of coumarin antibiotics bearing 5',5'-dialkylnoviose: biological activity of RU79115.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Coumarins; Hexoses; Microbial Sensitivity Tests | 2000 |
Synthesis of conformationally constrained analogues of linezolid: structure-activity relationship (SAR) studies on selected novel tricyclic oxazolidinones.
Topics: Acetamides; Anti-Bacterial Agents; Bacteria; Linezolid; Microbial Sensitivity Tests; Molecular Conformation; Molecular Mimicry; Oxazolidinones; Structure-Activity Relationship; Vancomycin Resistance | 2002 |
Synthesis and structure-activity relationships of 5-amino-6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-8-methylquinolonecarboxylic acid antibacterials having fluorinated 7-[(3R)-3-(1-aminocyclopropan-1-yl)pyrrolidin-1-yl] substituents.
Topics: Anti-Bacterial Agents; Cyclopropanes; Drug Resistance, Bacterial; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones; Stereoisomerism; Structure-Activity Relationship | 2003 |
Synthesis and in vitro activity of new methylenepiperidinyl and methylenepyrrolidinyl oxazolidinone antibacterial agents.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Area Under Curve; Bacteria; Drug Resistance, Bacterial; Enterococcus; Gram-Positive Bacteria; Indicators and Reagents; Male; Microbial Sensitivity Tests; Oxazoles; Piperidines; Pyrrolidines; Rats; Staphylococcus; Structure-Activity Relationship; Vancomycin | 2003 |
Synthesis and in vitro activity of novel isoxazolyl tetrahydropyridinyl oxazolidinone antibacterial agents.
Topics: Anti-Bacterial Agents; Enterococcus; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Staphylococcus; Structure-Activity Relationship | 2003 |
Influence of ethylene-oxy spacer group on the activity of linezolid: synthesis of potent antibacterials possessing a thiocarbonyl group.
Topics: Acetamides; Anti-Infective Agents; Bacteria; Ethylenes; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Structure-Activity Relationship; Thioacetamide | 2003 |
Iclaprim, a novel diaminopyrimidine with potent activity on trimethoprim sensitive and resistant bacteria.
Topics: Animals; Drug Resistance, Bacterial; Folic Acid Antagonists; Lung; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Pyrimidines; Sepsis; Staphylococcus aureus; Structure-Activity Relationship; Tetrahydrofolate Dehydrogenase; Trimethoprim Resistance; Vancomycin | 2003 |
DNA binding ligands with in vivo efficacy in murine models of bacterial infection: optimization of internal aromatic amino acids.
Topics: Amino Acids, Aromatic; Animals; Anti-Bacterial Agents; Disease Models, Animal; DNA; Ligands; Lung Diseases; Mice; Peritonitis; Staphylococcal Infections; Staphylococcus aureus; Streptococcal Infections; Streptococcus pneumoniae | 2004 |
Synthesis and antibacterial activity of novel 6-fluoro-1-[(1R,2S)-2-fluorocyclopropan-1-yl]-4-oxoquinoline-3-carboxylic acids bearing cyclopropane-fused 2-amino-8-azabicyclo[4.3.0]nonan-8-yl substituents at the C-7 position.
Topics: Anti-Infective Agents; Cyclopropanes; DNA Topoisomerase IV; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; Quinolones; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2004 |
Aryl urea analogs with broad-spectrum antibacterial activity.
Topics: Anti-Bacterial Agents; Evaluation Studies as Topic; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship; Thiourea | 2004 |
Synthesis and SAR of novel oxazolidinones: discovery of ranbezolid.
Topics: Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Furans; Gram-Positive Bacteria; Heterocyclic Compounds; Mice; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcal Infections; Structure-Activity Relationship | 2005 |
A chiral benzoquinolizine-2-carboxylic acid arginine salt active against vancomycin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Clinical Trials, Phase I as Topic; Dogs; Drug Resistance, Multiple, Bacterial; Female; Fluoroquinolones; Half-Life; Humans; Infusions, Intravenous; Injections, Intravenous; Male; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Mutation; Prodrugs; Quinolizines; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Vancomycin Resistance | 2005 |
Antibacterial, partially acetylated oligorhamnosides from Cleistopholis patens.
Topics: Annonaceae; Anti-Bacterial Agents; Gabon; Glycosides; Methicillin Resistance; Molecular Structure; Plant Leaves; Plants, Medicinal; Staphylococcus aureus | 2006 |
Synthesis of novel tricyclic oxazolidinones by a tandem SN2 and SNAr reaction: SAR studies on conformationally constrained analogues of Linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Chemistry, Pharmaceutical; Drug Design; Drug Resistance, Bacterial; Drug Resistance, Microbial; Fluorine; Linezolid; Microbial Sensitivity Tests; Models, Chemical; Molecular Conformation; Oxazoles; Oxazolidinones; Structure-Activity Relationship | 2006 |
In vitro activities of the lipopeptides palmitoyl (Pal)-Lys-Lys-NH(2) and Pal-Lys-Lys alone and in combination with antimicrobial agents against multiresistant gram-positive cocci.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Drug Synergism; Gram-Positive Cocci; Hemolysis; Humans; Lipoproteins; Microbial Sensitivity Tests; Molecular Structure; Peptides | 2007 |
Influence on mitochondria and cytotoxicity of different antibiotics administered in high concentrations on primary human osteoblasts and cell lines.
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Antimycin A; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cells, Cultured; Chloramphenicol; Clindamycin; Dose-Response Relationship, Drug; Fluoroquinolones; Glycolysis; HeLa Cells; Humans; Lactic Acid; Linezolid; Macrolides; Mitochondria; Osteoblasts; Oxazolidinones; Rotenone; Tetracyclines; Time Factors | 2007 |
In vitro antibacterial activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Staphylococcus; Streptococcus | 2007 |
Structure-antibacterial activity of arylcarbonyl- and arylsulfonyl-piperazine 5-triazolylmethyl oxazolidinones.
Topics: Anti-Bacterial Agents; Colony Count, Microbial; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Oxazolidinones; Piperazines; Stereoisomerism; Structure-Activity Relationship; Sulfones; Triazoles | 2007 |
Synthesis, SAR and antibacterial studies on novel chalcone oxazolidinone hybrids.
Topics: Anti-Bacterial Agents; Chalcones; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Stereoisomerism; Structure-Activity Relationship; Thiocarbamates | 2007 |
In vitro effects of antimicrobial agents on planktonic and biofilm forms of Staphylococcus lugdunensis clinical isolates.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Biofilms; DNA, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Nafcillin; Oxazolidinones; Penicillin-Binding Proteins; Penicillins; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcal Infections; Staphylococcus; Tetracycline | 2007 |
Antimicrobial activities of ceragenins against clinical isolates of resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Drug Resistance, Microbial; Microbial Sensitivity Tests; Staphylococcus aureus; Steroids; Vancomycin Resistance | 2007 |
Clonal diversity and resistance mechanisms in tetracycline-nonsusceptible Streptococcus pneumoniae isolates in Poland.
Topics: Bacterial Proteins; Cell Lineage; DNA Transposable Elements; Genetic Variation; Poland; Streptococcus pneumoniae; Tetracycline; Tetracycline Resistance | 2007 |
Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis.
Topics: Anti-Bacterial Agents; Antitubercular Agents; DNA, Bacterial; Drug Evaluation, Preclinical; Mycobacterium tuberculosis; Oxygen | 2007 |
Daptomycin susceptibility of unusual gram-positive bacteria: comparison of results obtained by the Etest and the broth microdilution method.
Topics: Culture Media; Daptomycin; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Microbial Sensitivity Tests | 2007 |
In vitro activity of aurein 1.2 alone and in combination with antibiotics against gram-positive nosocomial cocci.
Topics: Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cross Infection; Drug Synergism; Drug Therapy, Combination; Gram-Positive Cocci; Microbial Sensitivity Tests | 2007 |
Isothiazoloquinolones with enhanced antistaphylococcal activities against multidrug-resistant strains: effects of structural modifications at the 6-, 7-, and 8-positions.
Topics: Animals; Anti-Bacterial Agents; Cell Line, Tumor; Drug Resistance, Multiple, Bacterial; Female; Humans; Methicillin Resistance; Mice; Quinolones; Staphylococcus aureus; Structure-Activity Relationship; Thiazoles; Topoisomerase II Inhibitors | 2007 |
Effect of antibiotics on Staphylococcus aureus producing Panton-Valentine leukocidin.
Topics: Anti-Bacterial Agents; Bacterial Toxins; Exotoxins; Leukocidins; Microbial Sensitivity Tests; Staphylococcus aureus | 2007 |
In vitro and in vivo antibacterial activities of heteroaryl isothiazolones against resistant gram-positive pathogens.
Topics: Animals; Anti-Infective Agents; Drug Resistance, Bacterial; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Mice; Microbial Sensitivity Tests; Quinolones; Thiazoles | 2007 |
A new class of anti-MRSA and anti-VRE agents: preparation and antibacterial activities of indole-containing compounds.
Topics: Anti-Bacterial Agents; Enterococcus; Indicators and Reagents; Indoles; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Vancomycin Resistance | 2007 |
Rapid bactericidal activity of daptomycin against methicillin-resistant and methicillin-susceptible Staphylococcus aureus peritonitis in mice as measured with bioluminescent bacteria.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Colony Count, Microbial; Daptomycin; Female; Linezolid; Luminescent Measurements; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Neutropenia; Oxazolidinones; Peritonitis; Staphylococcus aureus | 2007 |
Comparative activities of daptomycin, linezolid, and tigecycline against catheter-related methicillin-resistant Staphylococcus bacteremic isolates embedded in biofilm.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Biofilms; Catheterization, Central Venous; Daptomycin; Humans; Linezolid; Methicillin Resistance; Minocycline; Oxazolidinones; Staphylococcus aureus; Tigecycline | 2007 |
Single-dose oral amoxicillin or linezolid for prophylaxis of experimental endocarditis due to vancomycin-susceptible and vancomycin-resistant Enterococcus faecalis.
Topics: Acetamides; Administration, Oral; Amoxicillin; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Endocarditis, Bacterial; Enterococcus faecalis; Female; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Rats; Rats, Wistar; Vancomycin Resistance | 2007 |
Synthesis and antibacterial activity of oxazolidinones containing triazolyl group.
Topics: Anti-Bacterial Agents; Gram-Positive Bacteria; Microbial Sensitivity Tests; Oxazolidinones; Structure-Activity Relationship; Triazoles | 2007 |
In vitro activities of CG400549, a novel FabI inhibitor, against recently isolated clinical staphylococcal strains in Korea.
Topics: Acetamides; Anti-Infective Agents; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Humans; In Vitro Techniques; Korea; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Pyridines; Staphylococcus; Staphylococcus aureus; Thienopyridines; Thiophenes | 2007 |
Interaction of the GraRS two-component system with the VraFG ABC transporter to support vancomycin-intermediate resistance in Staphylococcus aureus.
Topics: Anti-Bacterial Agents; ATP-Binding Cassette Transporters; Bacterial Proteins; Gene Expression Regulation, Bacterial; Humans; Microbial Sensitivity Tests; Polymyxin B; Signal Transduction; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Vancomycin Resistance | 2007 |
Prevalence, characteristics, and molecular epidemiology of macrolide and fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae at five tertiary-care hospitals in Korea.
Topics: Anti-Bacterial Agents; Community-Acquired Infections; DNA, Bacterial; Drug Resistance, Bacterial; Erythromycin; Fluoroquinolones; Genes, Bacterial; Hospitals; Humans; Korea; Levofloxacin; Macrolides; Microbial Sensitivity Tests; Molecular Epidemiology; Mutation; Ofloxacin; Pneumococcal Infections; Polymerase Chain Reaction; Prevalence; Reserpine; Respiratory Tract Infections; Retrospective Studies; Streptococcus pneumoniae | 2007 |
Synthesis and antibacterial activity of novel fluoroquinolones containing substituted piperidines.
Topics: Anti-Bacterial Agents; Bacteria; Fluoroquinolones; Microbial Sensitivity Tests; Molecular Structure; Piperidines | 2007 |
In vivo efficacy of ceftaroline (PPI-0903), a new broad-spectrum cephalosporin, compared with linezolid and vancomycin against methicillin-resistant and vancomycin-intermediate Staphylococcus aureus in a rabbit endocarditis model.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Area Under Curve; Ceftaroline; Cephalosporins; Chromatography, High Pressure Liquid; Colony Count, Microbial; Endocarditis, Bacterial; Immunoenzyme Techniques; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin; Vancomycin Resistance | 2007 |
In vitro activity of telavancin against gram-positive clinical isolates recently obtained in Europe.
Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Europe; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Lipoglycopeptides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus agalactiae; Streptococcus pyogenes; Vancomycin Resistance; Viridans Streptococci | 2007 |
Synthesis and antibacterial activity of novel oxazolidinones with methylene oxygen- and methylene sulfur-linked substituents at C5-position.
Topics: Acetamides; Anti-Bacterial Agents; Chemistry, Pharmaceutical; Drug Design; Drug Resistance, Bacterial; Gram-Negative Bacteria; Linezolid; Mass Spectrometry; Methicillin; Microbial Sensitivity Tests; Models, Chemical; Oxazolidinones; Piperazine; Piperazines; Sulfur; Temperature; Thiocarbamates | 2007 |
Discovery of 1,4-dihydroxy-2-naphthoate [corrected] prenyltransferase inhibitors: new drug leads for multidrug-resistant gram-positive pathogens.
Topics: Alkyl and Aryl Transferases; Anti-Bacterial Agents; Benzophenones; Gram-Positive Bacteria; Methicillin Resistance; Microbial Sensitivity Tests; Mycobacterium; Naphthols; Staphylococcus aureus; Staphylococcus epidermidis | 2007 |
Mupirocin-resistant, methicillin-resistant Staphylococcus aureus strains in Canadian hospitals.
Topics: Aged; Anti-Bacterial Agents; Canada; Cross Infection; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Female; Hospitals; Humans; Male; Methicillin Resistance; Microbial Sensitivity Tests; Mupirocin; Staphylococcal Infections; Staphylococcus aureus | 2007 |
Antistaphylococcal activity of CG400549, a new experimental FabI inhibitor, compared with that of other agents.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Multiple, Bacterial; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enzyme Inhibitors; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Pyridines; Staphylococcus aureus; Thienopyridines; Thiophenes; Virginiamycin | 2007 |
Synthesis and antibacterial activity of potent heterocyclic oxazolidinones and the identification of RBx 8700.
Topics: Anti-Bacterial Agents; Enterococcus faecium; Molecular Structure; Oxazolidinones; Staphylococcus aureus; Streptococcus pyogenes; Structure-Activity Relationship | 2007 |
Synthesis and biological evaluation of new N-linked 5-triazolylmethyl oxazolidinones.
Topics: Animals; Anti-Bacterial Agents; Aza Compounds; Gram-Positive Bacteria; Methylation; Mice; Molecular Structure; Oxazolidinones; Structure-Activity Relationship | 2008 |
Vancomycin-resistant Staphylococcus aureus isolates associated with Inc18-like vanA plasmids in Michigan.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Carbon-Oxygen Ligases; Conjugation, Genetic; DNA Transposable Elements; DNA, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterococcus faecalis; Humans; Michigan; Microbial Sensitivity Tests; Plasmids; Polymerase Chain Reaction; Restriction Mapping; Staphylococcal Infections; Staphylococcus aureus; Vancomycin Resistance | 2008 |
Synthesis, SAR, and antibacterial activity of novel oxazolidinone analogues possessing urea functionality.
Topics: Anti-Bacterial Agents; Enterococcus faecium; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus; Structure-Activity Relationship | 2008 |
Antimicrobial activities of Ceftaroline and ME1036 tested against clinical strains of community-acquired methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; beta-Lactams; Carbapenems; Ceftaroline; Cephalosporins; Community-Acquired Infections; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; United States | 2008 |
Synthesis and structure-antibacterial activity of triazolyl oxazolidinones containing long chain acyl moiety.
Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Oxazolidinones; Structure-Activity Relationship; Triazoles | 2008 |
Antimicrobial-resistant pathogens in intensive care units in Canada: results of the Canadian National Intensive Care Unit (CAN-ICU) study, 2005-2006.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; beta-Lactamases; Canada; Drug Resistance, Bacterial; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Intensive Care Units; Male; Microbial Sensitivity Tests; Middle Aged; Population Surveillance | 2008 |
In vitro activities of the Rx-01 oxazolidinones against hospital and community pathogens.
Topics: Anti-Infective Agents; Bacteria; Community-Acquired Infections; Cross Infection; Enterococcus; Humans; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Respiratory System; Staphylococcus; Staphylococcus aureus; Streptococcus; Streptococcus pneumoniae | 2008 |
Efficacies of ceftobiprole medocaril and comparators in a rabbit model of osteomyelitis due to methicillin-resistant Staphylococcus aureus.
Topics: Animals; Body Weight; Cephalosporins; Disease Models, Animal; Methicillin Resistance; Microbial Sensitivity Tests; Osteomyelitis; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Tibia | 2008 |
First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Proteins; Drug Resistance, Bacterial; Humans; Linezolid; Methyltransferases; Microbial Sensitivity Tests; Molecular Sequence Data; Oxazolidinones; Sequence Analysis, DNA; Staphylococcal Infections; Staphylococcus aureus; Staphylococcus epidermidis | 2008 |
Pharmacodynamic characterization of ceftobiprole in experimental pneumonia caused by phenotypically diverse Staphylococcus aureus strains.
Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Community-Acquired Infections; Cross Infection; Disease Models, Animal; Drug Resistance, Bacterial; Female; Humans; Methicillin Resistance; Mice; Mice, Inbred BALB C; Phenotype; Pneumonia, Staphylococcal; Staphylococcus aureus | 2008 |
In vitro antibacterial activity of CE-156811, a novel analog derived from hygromycin A.
Topics: Acetamides; Anti-Bacterial Agents; Cinnamates; Dioxoles; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Hygromycin B; In Vitro Techniques; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Comparative surveillance study of telavancin activity against recently collected gram-positive clinical isolates from across the United States.
Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Lipoglycopeptides; Microbial Sensitivity Tests; Prospective Studies; Staphylococcus aureus; Streptococcus; Streptococcus pneumoniae; United States | 2008 |
In vitro activity of telavancin against resistant gram-positive bacteria.
Topics: Aminoglycosides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; In Vitro Techniques; Lipoglycopeptides; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus; Streptococcus | 2008 |
Activities of ceftobiprole, linezolid, vancomycin, and daptomycin against community-associated and hospital-associated methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Cephalosporins; Community-Acquired Infections; Cross Infection; Daptomycin; Drug Synergism; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2008 |
In vitro profiling of ceftaroline against a collection of recent bacterial clinical isolates from across the United States.
Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Microbial Sensitivity Tests; United States | 2008 |
Improved antimicrobial activity of linezolid against vancomycin-intermediate Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Community-Acquired Infections; Cross Infection; Drug Resistance, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin Resistance | 2008 |
Synthesis, antibacterial and anticonvulsant evaluations of some cyclic enaminones.
Topics: Amines; Anti-Bacterial Agents; Anticonvulsants; Magnetic Resonance Spectroscopy; Spectrophotometry, Ultraviolet; Structure-Activity Relationship | 2009 |
Effect of electrical current on the activities of antimicrobial agents against Pseudomonas aeruginosa, Staphylococcus aureus, and Staphylococcus epidermidis biofilms.
Topics: Anti-Infective Agents; Biofilms; Bioreactors; Electricity; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Staphylococcus aureus; Staphylococcus epidermidis | 2009 |
Serial daptomycin selection generates daptomycin-nonsusceptible Staphylococcus aureus strains with a heterogeneous vancomycin-intermediate phenotype.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Daptomycin; Drug Resistance, Bacterial; Humans; Membrane Fluidity; Membrane Potentials; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oligonucleotide Array Sequence Analysis; Phenotype; Vancomycin | 2008 |
In vitro activities of doripenem, a new broad-spectrum carbapenem, against recently collected clinical anaerobic isolates, with emphasis on the Bacteroides fragilis group.
Topics: Anti-Bacterial Agents; Bacteria, Anaerobic; Bacteroides fragilis; Carbapenems; Doripenem; Drug Resistance, Bacterial; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests | 2008 |
In vitro activity of TR-700, the antibacterial moiety of the prodrug TR-701, against linezolid-resistant strains.
Topics: Acetamides; Anti-Bacterial Agents; Binding Sites; Drug Resistance, Bacterial; Enterococcus; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Models, Molecular; Oxazolidinones; Prodrugs; Staphylococcus aureus | 2008 |
Establishment of in vitro susceptibility testing methodologies and comparative activities of piperacillin in combination with the penem {beta}-lactamase inhibitor BLI-489.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; beta-Lactamase Inhibitors; Drug Combinations; Enzyme Inhibitors; Humans; Lactams; Microbial Sensitivity Tests; Piperacillin | 2009 |
Oritavancin kills stationary-phase and biofilm Staphylococcus aureus cells in vitro.
Topics: Anti-Bacterial Agents; Biofilms; Colony Count, Microbial; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Glycopeptides; Kinetics; Lipoglycopeptides; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Plankton; Staphylococcus aureus; Vancomycin; Vancomycin Resistance | 2009 |
Contribution of vraSR and graSR point mutations to vancomycin resistance in vancomycin-intermediate Staphylococcus aureus.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Bacterial Proteins; Base Sequence; Chromosome Walking; DNA-Binding Proteins; Genetic Engineering; Genome, Bacterial; Humans; Microbial Sensitivity Tests; Molecular Sequence Data; Point Mutation; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Staphylococcus aureus; Vancomycin; Vancomycin Resistance | 2009 |
Activities of dalbavancin against a worldwide collection of 81,673 gram-positive bacterial isolates.
Topics: Anti-Bacterial Agents; Asia; Drug Resistance, Bacterial; Europe; Gram-Positive Bacteria; Humans; Latin America; Microbial Sensitivity Tests; North America; Pacific Ocean; Quality Control; Teicoplanin; Vancomycin | 2009 |
Antistaphylococcal activity of dihydrophthalazine antifolates, a family of novel antibacterial drugs.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Folic Acid Antagonists; Microbial Sensitivity Tests; Phthalazines; Staphylococcus aureus; Staphylococcus epidermidis; Tetrahydrofolate Dehydrogenase | 2009 |
Intracellular activity of antibiotics in a model of human THP-1 macrophages infected by a Staphylococcus aureus small-colony variant strain isolated from a cystic fibrosis patient: pharmacodynamic evaluation and comparison with isogenic normal-phenotype a
Topics: Anti-Bacterial Agents; Cell Line; Cystic Fibrosis; Dose-Response Relationship, Drug; Fusidic Acid; Gentamicins; Humans; Macrophages; Microbial Sensitivity Tests; Oxacillin; Phenotype; Protein Binding; Staphylococcus aureus; Thymidine | 2009 |
In vivo activity of the pyrrolopyrazolyl-substituted oxazolidinone RWJ-416457.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Disease Models, Animal; Female; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Oxazolidinones; Pneumococcal Infections; Staphylococcal Infections; Staphylococcal Skin Infections; Staphylococcus aureus; Streptococcus pneumoniae; Treatment Outcome; Vancomycin | 2009 |
Impact of sarA on antibiotic susceptibility of Staphylococcus aureus in a catheter-associated in vitro model of biofilm formation.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Catheterization; Daptomycin; Microbial Sensitivity Tests; Mutation; Staphylococcus aureus; Vancomycin | 2009 |
Potency and bactericidal activity of iclaprim against recent clinical gram-positive isolates.
Topics: Anti-Bacterial Agents; Enterococcus faecalis; Europe; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Hospitalization; Humans; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrimidines; Staphylococcus aureus; Streptococcus; United States | 2009 |
Impact of human serum albumin on oritavancin in vitro activity against enterococci.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enterococcus; Glycopeptides; Lipoglycopeptides; Microbial Sensitivity Tests; Protein Binding; Serum Albumin | 2009 |
Synthesis and antibacterial activity of novel 5-(4-methyl-1H-1,2,3-triazole) methyl oxazolidinones.
Topics: Anti-Bacterial Agents; Bacteria; Drug Design; Microbial Sensitivity Tests; Monoamine Oxidase Inhibitors; Oxazolidinones; Piperazine; Piperazines | 2009 |
Resistance selection studies comparing the activity of razupenem (PTZ601) to vancomycin and linezolid against eight methicillin-resistant and two methicillin-susceptible Staphylococcus aureus strains.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus; Vancomycin | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Synthesis and antibacterial evaluation of isoxazolinyl oxazolidinones: Search for potent antibacterial.
Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Oxazolidinones | 2009 |
Nocathiacin analogs: Synthesis and antibacterial activity of novel water-soluble amides.
Topics: Amides; Animals; Anti-Bacterial Agents; Intercellular Signaling Peptides and Proteins; Mice; Microbial Sensitivity Tests; Peptides; Piperazines; Solubility; Structure-Activity Relationship; Water | 2009 |
AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity.
Topics: Anti-Bacterial Agents; Benzofurans; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Enterobacteriaceae; Enterococcus; Microbial Sensitivity Tests; Moraxella catarrhalis; Pyrones; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Staphylococcus epidermidis; Streptococcus pneumoniae | 2009 |
In vitro activity of TR-700, the active ingredient of the antibacterial prodrug TR-701, a novel oxazolidinone antibacterial agent.
Topics: Anti-Bacterial Agents; Bacteria; Enterococcus; Haemophilus influenzae; Microbial Sensitivity Tests; Moraxella catarrhalis; Oxazolidinones; Staphylococcus; Streptococcus | 2009 |
Prevalence and characterization of heterogeneous vancomycin-intermediate Staphylococcus aureus isolates from 14 cities in China.
Topics: Anti-Bacterial Agents; China; Cities; Drug Resistance, Multiple, Bacterial; Humans; Methicillin-Resistant Staphylococcus aureus; Staphylococcal Infections; Vancomycin; Vancomycin Resistance | 2009 |
In vitro activities of telavancin and six comparator agents against anaerobic bacterial isolates.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteria, Anaerobic; Clostridioides difficile; Gram-Negative Bacteria; Gram-Positive Bacteria; Lipoglycopeptides; Microbial Sensitivity Tests | 2009 |
Role of porins in the susceptibility of Mycobacterium smegmatis and Mycobacterium chelonae to aldehyde-based disinfectants and drugs.
Topics: Antitubercular Agents; Disinfectants; Drug Resistance, Bacterial; Glutaral; Microbial Sensitivity Tests; Molecular Sequence Data; Mutation; Mycobacterium chelonae; Mycobacterium smegmatis; o-Phthalaldehyde; Porins | 2009 |
In vivo characterization of the peptide deformylase inhibitor LBM415 in murine infection models.
Topics: Acetamides; Amidohydrolases; Animals; Anti-Infective Agents; Female; Linezolid; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Peptides; Pneumonia; Staphylococcus aureus; Streptococcus pneumoniae; Thigh | 2009 |
Efficacy of high doses of daptomycin versus alternative therapies against experimental foreign-body infection by methicillin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Daptomycin; Foreign-Body Reaction; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Rats; Rats, Wistar | 2009 |
In vitro activities of panduratin A against clinical Staphylococcus strains.
Topics: Anti-Bacterial Agents; Chalcones; Humans; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus; Zingiberaceae | 2009 |
In vitro bactericidal activity of iclaprim in human plasma.
Topics: Anti-Bacterial Agents; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Plasma; Pyrimidines; Staphylococcus aureus | 2009 |
Design, synthesis, and structure-activity relationships of benzophenone-based tetraamides as novel antibacterial agents.
Topics: Amides; Animals; Anti-Bacterial Agents; Benzophenones; Cell Membrane; Cell Wall; CHO Cells; Cricetinae; Cricetulus; DNA, Bacterial; Drug Design; Drug Resistance, Bacterial; Escherichia coli; Gram-Negative Bacteria; Gram-Positive Bacteria; Microbial Sensitivity Tests; Protein Biosynthesis; RNA, Bacterial; Staphylococcus aureus; Structure-Activity Relationship | 2009 |
Water-soluble phosphate prodrugs of pleuromutilin analogues with potent in vivo antibacterial activity against Gram-positive pathogens.
Topics: Animals; Anti-Bacterial Agents; Diterpenes; Gram-Positive Bacteria; Mice; Microbial Sensitivity Tests; Phosphates; Pleuromutilins; Polycyclic Compounds; Prodrugs; Rats; Rats, Sprague-Dawley; Solubility; Staphylococcal Infections; Structure-Activity Relationship; Water | 2009 |
Design, synthesis and biological evaluations of novel 7-[3-(1-aminocycloalkyl)pyrrolidin-1-yl]-6-desfluoro-8-methoxyquinolones with potent antibacterial activity against multi-drug resistant Gram-positive bacteria.
Topics: Anti-Bacterial Agents; Drug Design; Drug Resistance, Multiple; Gram-Positive Bacteria; Microbial Sensitivity Tests; Quinolones; Structure-Activity Relationship | 2009 |
Pharmacodynamic profile of tigecycline against methicillin-resistant Staphylococcus aureus in an experimental pneumonia model.
Topics: Animals; Anti-Bacterial Agents; Female; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Minocycline; Pneumonia; Staphylococcal Infections; Tigecycline | 2009 |
Comparative in vitro activity profile of oritavancin against recent gram-positive clinical isolates.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus faecium; Glycopeptides; Gram-Positive Bacteria; Humans; Lipoglycopeptides; Microbial Sensitivity Tests; Staphylococcus aureus; Streptococcus | 2009 |
In vitro activities of three new dihydrofolate reductase inhibitors against clinical isolates of gram-positive bacteria.
Topics: Folic Acid Antagonists; Gram-Positive Bacteria; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phthalazines; Staphylococcus aureus; Streptococcus | 2009 |
In vivo activity of a novel anti-methicillin-resistant Staphylococcus aureus cephalosporin, ceftaroline, against vancomycin-susceptible and -resistant Enterococcus faecalis strains in a rabbit endocarditis model: a comparative study with linezolid and van
Topics: Acetamides; Animals; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Endocarditis, Bacterial; Enterococcus faecalis; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Rabbits; Vancomycin; Vancomycin Resistance | 2009 |
Mutations in ribosomal protein L3 are associated with oxazolidinone resistance in staphylococci of clinical origin.
Topics: Acetamides; Binding Sites; Drug Resistance, Bacterial; Linezolid; Mutation; Oxazolidinones; Protein Structure, Secondary; Ribosomal Protein L3; Ribosomal Proteins; RNA, Ribosomal, 23S; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Tetrazoles | 2009 |
Correlation between vancomycin MIC values and those of other agents against gram-positive bacteria among patients with bloodstream infections caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Cohort Studies; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Retrospective Studies; Staphylococcal Infections; Vancomycin | 2009 |
Synthesis and antibacterial activity of isothiazolyl oxazolidinones and analogous 3(2H)-isothiazolones.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Mice; Microbial Sensitivity Tests; NIH 3T3 Cells; Oxazolidinones; Thiazoles | 2010 |
Novel 4-N-substituted aryl but-3-ene-1,2-dione derivatives of piperazinyloxazolidinones as antibacterial agents.
Topics: Anti-Bacterial Agents; Butanes; Dose-Response Relationship, Drug; Drug Design; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Stereoisomerism; Structure-Activity Relationship | 2009 |
In vivo activity of ceftobiprole in murine skin infections due to Staphylococcus aureus and Pseudomonas aeruginosa.
Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Bacterial Proteins; beta-Lactamases; Cephalosporins; Colony Count, Microbial; Dose-Response Relationship, Drug; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Half-Life; Immunocompromised Host; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Hairless; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Pseudomonas Infections; Skin Diseases, Infectious; Staphylococcal Infections; Staphylococcus aureus | 2010 |
Ceftobiprole is superior to vancomycin, daptomycin, and linezolid for treatment of experimental endocarditis in rabbits caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Cephalosporins; Chromatography, High Pressure Liquid; Daptomycin; Disease Models, Animal; Endocarditis, Bacterial; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Rabbits; Random Allocation; Vancomycin | 2010 |
Synthesis of nitroimidazole derived oxazolidinones as antibacterial agents.
Topics: Alkylation; Animals; Anti-Bacterial Agents; Bacteria; Cell Line; Cell Survival; Drug Resistance, Bacterial; Mice; Nitroimidazoles; Oxazolidinones | 2010 |
Identification of a plasmid-borne resistance gene cluster comprising the resistance genes erm(T), dfrK, and tet(L) in a porcine methicillin-resistant Staphylococcus aureus ST398 strain.
Topics: Animals; Anti-Bacterial Agents; Lincosamides; Macrolides; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Sequence Data; Multigene Family; Plasmids; Streptogramin B; Swine; Tetracycline Resistance; Trimethoprim | 2010 |
Distribution of serotypes, genotypes, and resistance determinants among macrolide-resistant Streptococcus pneumoniae isolates.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Child, Preschool; DNA Transposable Elements; Drug Resistance, Bacterial; Erythromycin; Genotype; Humans; Macrolides; Microbial Sensitivity Tests; New South Wales; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae | 2010 |
Comparative in vitro activities of nemonoxacin (TG-873870), a novel nonfluorinated quinolone, and other quinolones against clinical isolates.
Topics: Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Gram-Negative Bacteria; Gram-Positive Cocci; Humans; Microbial Sensitivity Tests; Moxifloxacin; Quinolines; Quinolones; Taiwan | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Comparative activities of TR-700 (torezolid) against staphylococcal blood isolates collected in Spain.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Bacterial; In Vitro Techniques; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Sepsis; Spain; Staphylococcal Infections; Tetrazoles; Vancomycin | 2010 |
Activity of ceftaroline against recent emerging serotypes of Streptococcus pneumoniae in the United States.
Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Communicable Diseases, Emerging; Drug Resistance, Multiple, Bacterial; Humans; In Vitro Techniques; Microbial Sensitivity Tests; Pneumococcal Infections; Serotyping; Streptococcus pneumoniae; United States | 2010 |
In vitro activity of telavancin against a contemporary worldwide collection of Staphylococcus aureus isolates.
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Bacterial; Humans; In Vitro Techniques; Linezolid; Lipoglycopeptides; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Virginiamycin | 2010 |
In vitro activity of ceftaroline against community-associated methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, and daptomycin-nonsusceptible Staphylococcus aureus isolates.
Topics: Ceftaroline; Cephalosporins; Daptomycin; Drug Resistance, Multiple, Bacterial; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Vancomycin; Vancomycin Resistance | 2010 |
Potent antimicrobial activity of 3-(4,5-diaryl-1H-imidazol-2-yl)-1H-indole derivatives against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Infective Agents; Enterococcus faecalis; Enterococcus faecium; Gram-Negative Bacteria; Gram-Positive Bacteria; Indoles; Methicillin-Resistant Staphylococcus aureus; Vancomycin | 2010 |
Design, synthesis, and antibacterial activity of 2,5-dihydropyrrole formyl hydroxyamino derivatives as novel peptide deformylase inhibitors.
Topics: Amidohydrolases; Amines; Anti-Bacterial Agents; Drug Design; Pyrroles; Structure-Activity Relationship | 2010 |
Development of daptomycin nonsusceptibility with heterogeneous vancomycin-intermediate resistance and oxacillin susceptibility in methicillin-resistant Staphylococcus aureus during high-dose daptomycin treatment.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Oxacillin; Oxazolidinones; Teicoplanin; Vancomycin Resistance | 2010 |
In vitro activity of the new multivalent glycopeptide-cephalosporin antibiotic TD-1792 against vancomycin-nonsusceptible Staphylococcus isolates.
Topics: Acetamides; Anti-Bacterial Agents; Cephalosporins; Daptomycin; Glycopeptides; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus; Staphylococcus aureus; Vancomycin; Vancomycin Resistance; Virginiamycin | 2010 |
First report of the multidrug resistance gene cfr and the phenicol resistance gene fexA in a Bacillus strain from swine feces.
Topics: Animals; Anti-Bacterial Agents; Bacillus; Bacterial Proteins; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Feces; Lincosamides; Macrolides; Microbial Sensitivity Tests; Molecular Sequence Data; Streptogramin B; Swine | 2010 |
Inhibition of antibiotic-resistant Staphylococcus aureus by the broad-spectrum dihydrofolate reductase inhibitor RAB1.
Topics: Anti-Bacterial Agents; Enzyme Inhibitors; Inhibitory Concentration 50; Microbial Sensitivity Tests; Protein Structure, Secondary; Protein Structure, Tertiary; Staphylococcus aureus; Tetrahydrofolate Dehydrogenase | 2010 |
Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates.
Topics: Anti-Bacterial Agents; Gram-Negative Aerobic Bacteria; Gram-Positive Bacteria; Indoles; Microbial Sensitivity Tests | 2010 |
Subinhibitory concentrations of protein synthesis-inhibiting antibiotics promote increased expression of the agr virulence regulator and production of phenol-soluble modulin cytolysins in community-associated methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Cytotoxins; Methicillin-Resistant Staphylococcus aureus; Protein Synthesis Inhibitors; Reverse Transcriptase Polymerase Chain Reaction; Trans-Activators; Virulence | 2010 |
vanM, a new glycopeptide resistance gene cluster found in Enterococcus faecium.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Chromatography, Liquid; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterococcus faecium; Glycopeptides; Mass Spectrometry; Microbial Sensitivity Tests; Molecular Sequence Data; Multigene Family; Polymerase Chain Reaction | 2010 |
Bottromycin derivatives: efficient chemical modifications of the ester moiety and evaluation of anti-MRSA and anti-VRE activities.
Topics: Animals; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcaceae; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Peptides, Cyclic; Plasma; Vancomycin | 2010 |
Elevated linezolid resistance in clinical cfr-positive Staphylococcus aureus isolates is associated with co-occurring mutations in ribosomal protein L3.
Topics: Acetamides; Anti-Infective Agents; Bacterial Proteins; Drug Resistance, Bacterial; Linezolid; Methyltransferases; Microbial Sensitivity Tests; Mutation; Oxazolidinones; Ribosomal Protein L3; Ribosomal Proteins; Staphylococcus aureus | 2010 |
Comparative efficacies of human simulated exposures of telavancin and vancomycin against methicillin-resistant Staphylococcus aureus with a range of vancomycin MICs in a murine pneumonia model.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Disease Models, Animal; Female; Lipoglycopeptides; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Pneumonia; Staphylococcal Infections; Vancomycin | 2010 |
In vitro and in vivo activities of LCB01-0371, a new oxazolidinone.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bacterial Infections; Gram-Positive Bacteria; Linezolid; Male; Mice; Mice, Inbred ICR; Oxazolidinones; Staphylococcus aureus; Vancomycin | 2010 |
Identification and characterization of the multidrug resistance gene cfr in a Panton-Valentine leukocidin-positive sequence type 8 methicillin-resistant Staphylococcus aureus IVa (USA300) isolate.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Drug Resistance, Multiple, Bacterial; Exotoxins; Leukocidins; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Molecular Sequence Data; Plasmids | 2010 |
Design, synthesis and antibacterial activity of 3-methylenepyrrolidine formyl hydroxyamino derivatives as novel peptide deformylase inhibitors.
Topics: Amidohydrolases; Anti-Bacterial Agents; Drug Design; Drug Resistance, Bacterial; Enzyme Inhibitors; Haemophilus influenzae; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrrolidines | 2011 |
A new DNA gyrase inhibitor subclass of the cyclothialidine family based on a bicyclic dilactam-lactone scaffold. Synthesis and antibacterial properties.
Topics: Animals; Anti-Bacterial Agents; Bacteria; DNA Gyrase; Enzyme Inhibitors; Lactams; Lactones; Mice; Microbial Sensitivity Tests; Models, Molecular; Peptides, Cyclic; Protein Conformation; Topoisomerase II Inhibitors | 2011 |
Exploration of the activity of 7-pyrrolidino-8-methoxyisothiazoloquinolones against methicillin-resistant Staphylococcus aureus (MRSA).
Topics: Anti-Bacterial Agents; DNA Topoisomerase IV; Drug Resistance, Multiple, Bacterial; Escherichia coli; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pyrrolidines; Quinolones; Stereoisomerism; Structure-Activity Relationship; Thiazoles; Topoisomerase II Inhibitors | 2011 |
Selenophene-containing inhibitors of type IIA bacterial topoisomerases.
Topics: Anti-Bacterial Agents; Cell Line, Tumor; DNA Topoisomerase IV; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Methicillin-Resistant Staphylococcus aureus; Organoselenium Compounds; Piperidines; Quinolines; Staphylococcus aureus; Stereoisomerism; Structure-Activity Relationship; Thiophenes; Topoisomerase II Inhibitors | 2011 |
7-Alkyl-N(2)-substituted-3-deazaguanines. Synthesis, DNA polymerase III inhibition and antibacterial activity.
Topics: Animals; Anti-Bacterial Agents; DNA Polymerase III; Enzyme Inhibitors; Escherichia coli; Gram-Positive Bacteria; Guanine; Mice; Microbial Sensitivity Tests; Staphylococcal Infections | 2011 |
Novel N-linked aminopiperidine inhibitors of bacterial topoisomerase type II with reduced pK(a): antibacterial agents with an improved safety profile.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Biological Availability; Dioxanes; DNA Topoisomerase IV; Dogs; Drug Resistance, Bacterial; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Guinea Pigs; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Piperidines; Quinolones; Staphylococcal Infections; Stereoisomerism; Structure-Activity Relationship; Topoisomerase II Inhibitors | 2012 |
From triclosan toward the clinic: discovery of nonbiocidal, potent FabI inhibitors for the treatment of resistant bacteria.
Topics: Animals; Anti-Infective Agents, Local; Benzamides; Cells, Cultured; Dogs; Drug Evaluation, Preclinical; Drug Resistance, Multiple, Bacterial; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Gram-Negative Bacteria; Humans; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Phenyl Ethers; Rats; Structure-Activity Relationship; Triclosan | 2012 |
Antibacterial butenolides from the Korean tunicate Pseudodistoma antinboja.
Topics: 4-Butyrolactone; Acetamides; Animals; Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Positive Bacteria; Linezolid; Marine Biology; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Oxazolidinones; Republic of Korea; Urochordata; Vancomycin | 2012 |
Design, synthesis and structure-activity relationships of substituted oxazole-benzamide antibacterial inhibitors of FtsZ.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Benzamides; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Structure; Oxazoles; Staphylococcus aureus; Structure-Activity Relationship | 2014 |
Discovery and in vivo evaluation of alcohol-containing benzothiazoles as potent dual-targeting bacterial DNA supercoiling inhibitors.
Topics: Alcohols; Anti-Bacterial Agents; Benzothiazoles; DNA, Bacterial; DNA, Superhelical; Dose-Response Relationship, Drug; Drug Discovery; Haemophilus influenzae; Microbial Sensitivity Tests; Molecular Structure; Staphylococcus; Structure-Activity Relationship | 2014 |
Synthesis, antibacterial activity, and biological evaluation of formyl hydroxyamino derivatives as novel potent peptide deformylase inhibitors against drug-resistant bacteria.
Topics: Amidohydrolases; Anti-Bacterial Agents; Bacteria; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enzyme Inhibitors; Microbial Sensitivity Tests; Molecular Structure; Oligopeptides; Structure-Activity Relationship | 2014 |
Synthesis and biological evaluation of novel peptide BF2 as an antibacterial agent against clinical isolates of vancomycin-resistant enterococci.
Topics: Amino Acid Sequence; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Cross Infection; Drug Synergism; Enterococcus faecalis; Enterococcus faecium; Erythrocytes; HEK293 Cells; Humans; Oligopeptides; Rats, Wistar; Vancomycin-Resistant Enterococci | 2014 |
Structure-activity relationship for the oxadiazole class of antibiotics.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Oxadiazoles; Staphylococcus aureus; Structure-Activity Relationship | 2015 |
Thiol activated prodrugs of sulfur dioxide (SO2) as MRSA inhibitors.
Topics: Anti-Bacterial Agents; Drug Design; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Prodrugs; Staphylococcal Infections; Structure-Activity Relationship; Sulfhydryl Compounds; Sulfur Dioxide | 2015 |
Rapid synthesis and antimicrobial activity of novel 4-oxazolidinone heterocycles.
Topics: Acinetobacter baumannii; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Microbial Sensitivity Tests; Molecular Structure; Oxazolidinones; Staphylococcus aureus; Structure-Activity Relationship | 2015 |
Discovery and characterization of aryl isonitriles as a new class of compounds versus methicillin- and vancomycin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Caco-2 Cells; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Drug Discovery; Humans; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Molecular Structure; Nitriles; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin Resistance | 2015 |
A stepwise dechlorination/cross-coupling strategy to diversify the vancomycin 'in-chloride'.
Topics: Anti-Bacterial Agents; Boronic Acids; Catalysis; Chlorides; Halogenation; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcus aureus; Vancomycin; Vancomycin Resistance | 2016 |
Phenylthiazole antibiotics: A metabolism-guided approach to overcome short duration of action.
Topics: Anti-Bacterial Agents; Cells, Cultured; Drug Resistance, Bacterial; Drug Stability; Half-Life; Humans; Keratinocytes; Methicillin-Resistant Staphylococcus aureus; Structure-Activity Relationship; Thiazoles | 2017 |
Cadiolides J-M, antibacterial polyphenyl butenolides from the Korean tunicate Pseudodistoma antinboja.
Topics: 4-Butyrolactone; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Gram-Positive Bacteria; Microbial Sensitivity Tests; Molecular Structure; Republic of Korea; Structure-Activity Relationship; Urochordata | 2017 |
Diaryltriazenes as antibacterial agents against methicillin resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis.
Topics: Anti-Bacterial Agents; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mycobacterium smegmatis; Triazenes | 2017 |
Phenylthiazole Antibacterial Agents Targeting Cell Wall Synthesis Exhibit Potent Activity in Vitro and in Vivo against Vancomycin-Resistant Enterococci.
Topics: Animals; Anti-Bacterial Agents; Caenorhabditis elegans; Cell Wall; Gram-Positive Bacterial Infections; Humans; Microbial Sensitivity Tests; Models, Molecular; Thiazoles; Vancomycin Resistance; Vancomycin-Resistant Enterococci | 2017 |
Diphenylurea derivatives for combating methicillin- and vancomycin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Caenorhabditis elegans; Carbanilides; Drug Resistance, Bacterial; Methicillin-Resistant Staphylococcus aureus; Staphylococcal Infections; Staphylococcus aureus; Vancomycin Resistance | 2017 |
The Berkeleylactones, Antibiotic Macrolides from Fungal Coculture.
Topics: Anti-Bacterial Agents; Coculture Techniques; Macrolides; Microbial Sensitivity Tests; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Penicillium; Streptococcus pneumoniae; Streptococcus pyogenes | 2017 |
Arylthiazole antibiotics targeting intracellular methicillin-resistant Staphylococcus aureus (MRSA) that interfere with bacterial cell wall synthesis.
Topics: Animals; Anti-Bacterial Agents; Bacillus subtilis; Cell Line; Cell Wall; Dose-Response Relationship, Drug; Macrophages; Methicillin-Resistant Staphylococcus aureus; Mice; Molecular Structure; Structure-Activity Relationship; Thiazoles | 2017 |
Novel Inhibitors of Staphyloxanthin Virulence Factor in Comparison with Linezolid and Vancomycin versus Methicillin-Resistant, Linezolid-Resistant, and Vancomycin-Intermediate Staphylococcus aureus Infections in Vivo.
Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Drug Resistance, Bacterial; Ether-A-Go-Go Potassium Channels; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Potassium Channel Blockers; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Structure-Activity Relationship; Vancomycin; Vancomycin Resistance; Xanthophylls | 2017 |
Biphenylthiazole antibiotics with an oxadiazole linker: An approach to improve physicochemical properties and oral bioavailability.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Biological Availability; Cell Line; Chemical Phenomena; Cricetinae; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxadiazoles; Rats; Solubility; Structure-Activity Relationship; Thiazoles | 2018 |
Design, Synthesis, and Antibacterial Evaluation of Oxazolidinones with Fused Heterocyclic C-Ring Substructure.
Topics: | 2017 |
Novel Terminal Bipheny-Based Diapophytoene Desaturases (CrtN) Inhibitors as Anti-MRSA/VISR/LRSA Agents with Reduced hERG Activity.
Topics: Animals; Drug Design; Enzyme Inhibitors; ERG1 Potassium Channel; HEK293 Cells; Hep G2 Cells; Humans; Inhibitory Concentration 50; Methicillin-Resistant Staphylococcus aureus; Mice; Oxidoreductases; Rats; Safety; Solubility; Structure-Activity Relationship; Water | 2018 |
Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Dose-Response Relationship, Drug; Drug Discovery; Drug Resistance, Bacterial; Humans; Linezolid; Methicillin; Mice; Microbial Sensitivity Tests; Molecular Structure; Oxidoreductases; Piperonyl Butoxide; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin | 2018 |
Design, synthesis and antibacterial evaluation of honokiol derivatives.
Topics: Anti-Bacterial Agents; Biphenyl Compounds; Cell Wall; Cyclization; Drug Design; Escherichia coli; Kinetics; Lignans; Linezolid; Microbial Sensitivity Tests; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin | 2018 |
Design, synthesis and biological evaluation of spiropyrimidinetriones oxazolidinone derivatives as antibacterial agents.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Design; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Oxazolidinones; Pyrimidinones; Spiro Compounds; Staphylococcus epidermidis; Structure-Activity Relationship; Vancomycin-Resistant Enterococci | 2018 |
Novel Staphyloxanthin Inhibitors with Improved Potency against Multidrug Resistant
Topics: | 2018 |
Phenylthiazoles with tert-Butyl side chain: Metabolically stable with anti-biofilm activity.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Caco-2 Cells; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Rats, Sprague-Dawley; Staphylococcal Infections; Thiazoles | 2018 |
An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration.
Topics: Anti-Bacterial Agents; Biofilms; Cyclization; Halogenation; HeLa Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phenazines | 2018 |
Halogenated quinolines bearing polar functionality at the 2-position: Identification of new antibacterial agents with enhanced activity against Staphylococcus epidermidis.
Topics: Anti-Bacterial Agents; Cell Survival; Dose-Response Relationship, Drug; Erythrocytes; Halogenation; HeLa Cells; Humans; Microbial Sensitivity Tests; Molecular Structure; Quinolines; Staphylococcus epidermidis; Structure-Activity Relationship | 2018 |
N-(1,3,4-oxadiazol-2-yl)benzamide analogs, bacteriostatic agents against methicillin- and vancomycin-resistant bacteria.
Topics: Animals; Anti-Bacterial Agents; Benzamides; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Enterococcus faecalis; Gram-Positive Bacterial Infections; Methicillin; Mice; Microbial Sensitivity Tests; Molecular Structure; Skin Diseases, Bacterial; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin; Wound Infection | 2018 |
Synthesis and antibacterial bioactivities of cationic deacetyl linezolid amphiphiles.
Topics: Anti-Bacterial Agents; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Erythrocytes; Gram-Negative Bacteria; Gram-Positive Bacteria; HeLa Cells; Humans; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Structure-Activity Relationship; Surface-Active Agents | 2018 |
Microwave-enhanced Friedländer synthesis for the rapid assembly of halogenated quinolines with antibacterial and biofilm eradication activities against drug resistant and tolerant bacteria.
Topics: | 2017 |
1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.
Topics: Anti-Bacterial Agents; Cell Survival; Dose-Response Relationship, Drug; Enterococcus faecalis; Enzyme Inhibitors; Humans; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Peptide Synthases; Semicarbazides; Staphylococcus aureus; Structure-Activity Relationship; THP-1 Cells | 2018 |
Synthesis, antituberculosis studies and biological evaluation of new quinoline derivatives carrying 1,2,4-oxadiazole moiety.
Topics: Antitubercular Agents; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Microsomes, Liver; Molecular Structure; Mycobacterium tuberculosis; Oxadiazoles; Quinolines; Structure-Activity Relationship | 2019 |
Semisynthesis of Platensimycin Derivatives with Antibiotic Activities in Mice via Suzuki-Miyaura Cross-Coupling Reactions.
Topics: Adamantane; Aminobenzoates; Anilides; Animals; Anti-Bacterial Agents; Disease Models, Animal; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Docking Simulation; Peritonitis; Staphylococcal Infections | 2018 |
Second-generation aryl isonitrile compounds targeting multidrug-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Cell Line; Cell Survival; Disease Models, Animal; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Nitriles; Skin Diseases; Staphylococcal Infections | 2019 |
Lipophilic efficient phenylthiazoles with potent undecaprenyl pyrophosphatase inhibitory activity.
Topics: Animals; Anti-Bacterial Agents; Carbon-13 Magnetic Resonance Spectroscopy; Cell Line; Chromatography, Liquid; Enzyme Inhibitors; Lipids; Macrophages; Mass Spectrometry; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Proton Magnetic Resonance Spectroscopy; Pyrophosphatases; Structure-Activity Relationship; Thiazoles | 2019 |
Discovery of 1,3,4-oxadiazol-2-one-containing benzamide derivatives targeting FtsZ as highly potent agents of killing a variety of MDR bacteria strains.
Topics: Bacterial Proteins; Benzamides; Cytoskeletal Proteins; Methicillin-Resistant Staphylococcus aureus | 2019 |
Phenylthiazoles with nitrogenous side chain: An approach to overcome molecular obesity.
Topics: Amines; Animals; Anti-Bacterial Agents; Cell Line; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Humans; Macrophages; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Molecular Structure; Obesity; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Structure-Activity Relationship; Thiazoles | 2019 |
Modifying the lipophilic part of phenylthiazole antibiotics to control their drug-likeness.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Caco-2 Cells; Cell Line; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Humans; Hydrophobic and Hydrophilic Interactions; Kinetics; Macrophages; Male; Mice; Microbial Sensitivity Tests; Molecular Structure; Rats; Rats, Sprague-Dawley; Staphylococcus; Structure-Activity Relationship; Thiazoles | 2020 |
N-thiadiazole-4-hydroxy-2-quinolone-3-carboxamides bearing heteroaromatic rings as novel antibacterial agents: Design, synthesis, biological evaluation and target identification.
Topics: Animals; Anti-Bacterial Agents; DNA Gyrase; Drug Design; Enterococcus faecalis; Enterococcus faecium; Female; Hep G2 Cells; Human Umbilical Vein Endothelial Cells; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Quinolones; Staphylococcus epidermidis; Structure-Activity Relationship; Thiadiazoles; Topoisomerase II Inhibitors | 2020 |
Oxadiazolylthiazoles as novel and selective antifungal agents.
Topics: Antifungal Agents; Aspergillus; Biofilms; Caco-2 Cells; Candida; Cryptococcus; Humans; Microbial Sensitivity Tests; Oxadiazoles; Stereoisomerism; Thiazoles | 2020 |
Structure-Activity Relationship for the Oxadiazole Class of Antibacterials.
Topics: | 2020 |
Exploration of the Structural Space in 4(3
Topics: Animals; Anti-Bacterial Agents; Female; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Neutropenia; Quinazolinones; Staphylococcus aureus; Structure-Activity Relationship | 2020 |
Pharmacomodulations of the benzoyl-thiosemicarbazide scaffold reveal antimicrobial agents targeting d-alanyl-d-alanine ligase in bacterio.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Enzyme Inhibitors; Escherichia; Microbial Sensitivity Tests; Molecular Structure; Peptide Synthases; Staphylococcus aureus; Structure-Activity Relationship | 2020 |
Evaluation of N-phenyl-2-aminothiazoles for treatment of multi-drug resistant and intracellular Staphylococcus aureus infections.
Topics: Animals; Anti-Bacterial Agents; Cell Line; Cell Survival; Dose-Response Relationship, Drug; Humans; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Microsomes, Liver; Molecular Structure; Staphylococcal Infections; Structure-Activity Relationship; Thiazoles | 2020 |
Lead optimization of 8-(methylamino)-2-oxo-1,2-dihydroquinolines as bacterial type II topoisomerase inhibitors.
Topics: Anti-Bacterial Agents; Cell Survival; DNA Topoisomerases, Type II; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Hep G2 Cells; Humans; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Models, Molecular; Molecular Structure; Quinolines; Streptococcus pneumoniae; Structure-Activity Relationship; Topoisomerase II Inhibitors; Transcriptional Regulator ERG; Vancomycin-Resistant Enterococci | 2020 |
Nature-Inspired (di)Azine-Bridged Bisindole Alkaloids with Potent Antibacterial
Topics: Alkaloids; Animals; Anti-Bacterial Agents; Cell Line; Cell Survival; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Indoles; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Peritonitis; Pyruvate Kinase; Rabbits | 2020 |
Potent trifluoromethoxy, trifluoromethylsulfonyl, trifluoromethylthio and pentafluorosulfanyl containing (1,3,4-oxadiazol-2-yl)benzamides against drug-resistant Gram-positive bacteria.
Topics: | 2020 |
Enhancing Antimicrobial Peptide Potency through Multivalent Presentation on Coiled-Coil Nanofibrils.
Topics: | 2021 |
4-4-(Anilinomethyl)-3-[4-(trifluoromethyl)phenyl]-1H-pyrazol-1-ylbenzoic acid derivatives as potent anti-gram-positive bacterial agents.
Topics: Aniline Compounds; Anti-Bacterial Agents; Biofilms; Cell Line; Cell Survival; Drug Resistance, Bacterial; Enterococcus faecalis; Gram-Positive Bacteria; Humans; Liver; Microbial Sensitivity Tests; Pyrazoles; Staphylococcus aureus; Structure-Activity Relationship | 2021 |
A Modular Synthetic Route Involving
Topics: Aniline Compounds; Animals; Anti-Bacterial Agents; Biofilms; Cell Line; Cell Survival; Disease Models, Animal; Drug Design; Female; Halogenation; Humans; Iron; Iron Deficiencies; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Mycobacterium tuberculosis; Phenazines; Staphylococcal Infections; Structure-Activity Relationship; Wound Healing | 2021 |
Design, synthesis and evaluation of novel 9-arylalkyl-10-methylacridinium derivatives as highly potent FtsZ-targeting antibacterial agents.
Topics: Acridines; Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Drug Design; Microbial Sensitivity Tests; Molecular Docking Simulation; Molecular Structure; Staphylococcus aureus; Structure-Activity Relationship | 2021 |
Modification of 5-methylphenanthridium from benzothiazoles to indoles as potent FtsZ inhibitors: Broadening the antibacterial spectrum toward vancomycin-resistant enterococci.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Benzothiazoles; Cytoskeletal Proteins; Humans; Indoles; Molecular Structure; Phenanthridines; Structure-Activity Relationship; Vancomycin-Resistant Enterococci | 2021 |
Design, synthesis, and antibacterial activity of
Topics: | 2021 |
SF
Topics: | 2021 |
Potentiating the intracellular killing of Staphylococcus aureus by dihydroquinazoline analogues as NorA efflux pump inhibitor.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cell Survival; Dose-Response Relationship, Drug; Humans; Microbial Sensitivity Tests; Molecular Structure; Multidrug Resistance-Associated Proteins; Quinazolines; Staphylococcus aureus; Structure-Activity Relationship; THP-1 Cells | 2022 |
Novel 2,4-disubstituted quinazoline analogs as antibacterial agents with improved cytotoxicity profile: Modification of the benzenoid part.
Topics: Anti-Bacterial Agents; Benzene Derivatives; Dose-Response Relationship, Drug; Enterococcus faecalis; Humans; Microbial Sensitivity Tests; Molecular Structure; Quinazolines; Staphylococcus aureus; Streptococcus pneumoniae; Structure-Activity Relationship | 2022 |
Exploring the structure-activity relationships of diphenylurea as an antibacterial scaffold active against methicillin- and vancomycin-resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Methicillin; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin; Vancomycin-Resistant Staphylococcus aureus | 2022 |
Novel benzothiazole‒urea hybrids: Design, synthesis and biological activity as potent anti-bacterial agents against MRSA.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Benzothiazoles; Biofilms; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Urea | 2022 |
Design, synthesis and activity against drug-resistant bacteria evaluation of C-20, C-23 modified 5-O-mycaminosyltylonolide derivatives.
Topics: Animals; Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Leucomycins; Mice; Microbial Sensitivity Tests; Structure-Activity Relationship | 2022 |
Membrane acting Povarov-Doebner derived compounds potently disperse preformed multidrug resistant Gram-positive bacterial biofilms.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Biofilms; Drug Resistance, Multiple, Bacterial; Humans; Mammals; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests | 2022 |
Developing the Natural Prenylflavone Artocarpin from
Topics: Animals; Anti-Bacterial Agents; Artocarpus; Biofilms; Flavonoids; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus | 2022 |
In vivo activities of U-100592 and U-100766, novel oxazolidinone antimicrobial agents, against experimental bacterial infections.
Topics: Acetamides; Administration, Oral; Animals; Anti-Bacterial Agents; Bacterial Infections; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Injections, Intravenous; Injections, Subcutaneous; Linezolid; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus aureus; Vancomycin | 1996 |
In vitro activities of U-100592 and U-100766, novel oxazolidinone antibacterial agents.
Topics: Acetamides; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Vancomycin | 1996 |
In vitro activities of oxazolidinone compounds U100592 and U100766 against Staphylococcus aureus and Staphylococcus epidermidis.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Nafcillin; Oxazoles; Oxazolidinones; Penicillins; Staphylococcus aureus; Staphylococcus epidermidis; Time Factors; Vancomycin | 1996 |
Comparative in vitro activities and postantibiotic effects of the oxazolidinone compounds eperezolid (PNU-100592) and linezolid (PNU-100766) versus vancomycin against Staphylococcus aureus, coagulase-negative staphylococci, Enterococcus faecalis, and Ente
Topics: Acetamides; Anti-Bacterial Agents; Coagulase; Enterococcus faecalis; Enterococcus faecium; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus aureus; Vancomycin | 1998 |
Successful treatment of persistent vancomycin-resistant Enterococcus faecium bacteremia with linezolid and gentamicin.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Bacteremia; Drug Resistance, Microbial; Drug Therapy, Combination; Enterococcus faecium; Female; Gentamicins; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Vancomycin | 1999 |
In vitro activity of linezolid against vancomycin-resistant enterococci, methicillin-resistant Staphylococcus aureus and penicillin-resistant Streptococcus pneumoniae.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus; Gram-Positive Bacterial Infections; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Penicillin Resistance; Pneumococcal Infections; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae; Vancomycin | 1999 |
In vitro activities of linezolid against important gram-positive bacterial pathogens including vancomycin-resistant enterococci.
Topics: Acetamides; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Resistance, Microbial; Enterococcus; Gram-Positive Bacteria; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus; Streptococcus; Teicoplanin; Vancomycin | 1999 |
Activities of the oxazolidinones linezolid and eperezolid in experimental intra-abdominal abscess due to Enterococcus faecalis or vancomycin-resistant Enterococcus faecium.
Topics: Abdominal Abscess; Acetamides; Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Bacterial Infections; Linezolid; Male; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Rats; Rats, Sprague-Dawley; Treatment Outcome; Vancomycin | 1999 |
In vitro activities of daptomycin, vancomycin, linezolid, and quinupristin-dalfopristin against Staphylococci and Enterococci, including vancomycin- intermediate and -resistant strains.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Multiple; Enterococcus; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Staphylococcus; Time Factors; Vancomycin; Virginiamycin | 2000 |
Successful treatment of vertebral osteomyelitis with linezolid in a patient receiving hemodialysis and with persistent methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus bacteremias.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Enterococcus; Gram-Positive Bacterial Infections; Humans; Linezolid; Methicillin Resistance; Osteomyelitis; Oxazolidinones; Renal Dialysis; Spinal Diseases; Spine; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2000 |
Treatment of a vancomycin-resistant Enterococcus faecium ventricular drain infection with quinupristin/dalfopristin and review of the literature.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Drug Resistance, Multiple; Drug Therapy, Combination; Enterococcus faecium; Fatal Outcome; Female; Gram-Positive Bacterial Infections; Humans; Hydrocephalus; Injections, Intravenous; Injections, Intraventricular; Injections, Spinal; Linezolid; Middle Aged; Oxazoles; Oxazolidinones; Subarachnoid Hemorrhage; Tomography, X-Ray Computed; Vancomycin; Ventriculoperitoneal Shunt; Virginiamycin | 2000 |
In situ measurement of linezolid and vancomycin concentrations in intravascular catheter-associated biofilm.
Topics: Acetamides; Anti-Bacterial Agents; Biofilms; Catheterization; Gram-Positive Bacteria; Humans; Linezolid; Oxazolidinones; Staphylococcus aureus; Staphylococcus epidermidis; Vancomycin | 2001 |
Efficacy of linezolid in a staphylococcal endocarditis rabbit model.
Topics: Acetamides; Administration, Oral; Animals; Anti-Bacterial Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Endocarditis, Bacterial; Injections, Intravenous; Linezolid; Male; Oxazolidinones; Rabbits; Specific Pathogen-Free Organisms; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin | 2001 |
Infections due to vancomycin-resistant Enterococcus faecium resistant to linezolid.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Vancomycin | 2001 |
Efficacy of linezolid in treatment of experimental endocarditis caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Administration, Oral; Animals; Anti-Bacterial Agents; Aortic Valve; Colony Count, Microbial; Endocarditis, Bacterial; Heart Valve Diseases; Kidney; Linezolid; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2001 |
Ciprofloxacin- and methicillin-resistant staphylococcus aureus susceptible to moxifloxacin, levofloxacin, teicoplanin, vancomycin and linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Aza Compounds; Base Sequence; Ciprofloxacin; Drug Resistance, Multiple; Fluoroquinolones; Humans; Levofloxacin; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Molecular Sequence Data; Moxifloxacin; Ofloxacin; Oxazolidinones; Polymerase Chain Reaction; Quinolines; Sensitivity and Specificity; Staphylococcus aureus; Teicoplanin; Vancomycin | 2001 |
Effect of linezolid in comparison with that of vancomycin on glycocalix production: in vitro study.
Topics: Acetamides; Anti-Bacterial Agents; Glycocalyx; Humans; Linezolid; Oxazolidinones; Protein Synthesis Inhibitors; Staphylococcus aureus; Vancomycin | 2002 |
In vitro bactericidal activity of daptomycin against staphylococci.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Drug Therapy, Combination; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Staphylococcus; Vancomycin; Virginiamycin | 2002 |
The use of linezolid in the treatment of vancomycin-resistant enterococcal septicaemia in two patients with burn injuries.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Burns; Drug Resistance, Microbial; Enterococcus; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Sepsis; Vancomycin | 2002 |
E test susceptibility testing of nosocomial Clostridium difficile isolates against metronidazole, vancomycin, fusidic acid and the novel agents moxifloxacin, gatifloxacin, and linezolid.
Topics: Acetamides; Anti-Infective Agents; Aza Compounds; Clostridioides difficile; Clostridium Infections; Cross Infection; Diarrhea; Fluoroquinolones; Fusidic Acid; Gatifloxacin; Humans; Linezolid; Metronidazole; Microbial Sensitivity Tests; Moxifloxacin; Oxazolidinones; Quinolines; Sensitivity and Specificity; Vancomycin | 2002 |
Economic evaluation of linezolid, flucloxacillin and vancomycin in the empirical treatment of cellulitis in UK hospitals: a decision analytical model.
Topics: Acetamides; Administration, Oral; Anti-Bacterial Agents; Cellulitis; Cost-Benefit Analysis; Decision Support Techniques; Decision Trees; Drug Administration Schedule; Drug Resistance, Bacterial; Drug Utilization Review; Floxacillin; Gram-Positive Bacterial Infections; Hospital Costs; Hospitals, Public; Humans; Infection Control; Infusions, Intravenous; Linezolid; Oxazolidinones; Practice Patterns, Physicians'; United Kingdom; Vancomycin | 2001 |
In vitro activity of linezolid, synercid and telithromycin against genetically defined high level fluoroquinolone-resistant methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Drug Resistance, Multiple; In Vitro Techniques; Ketolides; Linezolid; Macrolides; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus; Vancomycin; Virginiamycin | 2002 |
In vitro activity of linezolid, quinupristin-dalfopristin, vancomycin, teicoplanin, moxifloxacin and mupirocin against methicillin-resistant Staphylococcus aureus: comparative evaluation by the E test and a broth microdilution method.
Topics: Acetamides; Anti-Bacterial Agents; Aza Compounds; Drug Resistance, Bacterial; Fluoroquinolones; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Moxifloxacin; Mupirocin; Oxazolidinones; Quinolines; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Vancomycin; Virginiamycin | 2002 |
Efficacy of linezolid against methicillin-resistant or vancomycin-insensitive Staphylococcus aureus in a model of hematogenous pulmonary infection.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Disease Models, Animal; Linezolid; Male; Methicillin Resistance; Mice; Oxazolidinones; Respiratory Tract Infections; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Vancomycin | 2002 |
In vivo efficacy of continuous infusion versus intermittent dosing of linezolid compared to vancomycin in a methicillin-resistant Staphylococcus aureus rabbit endocarditis model.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Area Under Curve; Dose-Response Relationship, Drug; Endocarditis, Bacterial; Female; Half-Life; Infusions, Intravenous; Linezolid; Methicillin Resistance; Oxazolidinones; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2002 |
The in vitro and in vivo antibacterial characterization of vancomycin and linezolid against vancomycin-susceptible and -resistant enterococci.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Drug Evaluation, Preclinical; Enterococcus faecalis; Humans; Linezolid; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Oxazolidinones; Vancomycin; Vancomycin Resistance | 2002 |
The efficacy and safety of linezolid as treatment for Staphylococcus aureus infections in compassionate use patients who are intolerant of, or who have failed to respond to, vancomycin.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Clinical Protocols; Female; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Vancomycin Resistance | 2002 |
Synthesis and antibacterial activity of 5-substituted oxazolidinones.
Topics: Acetamides; Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Structure-Activity Relationship; Triazoles; Vancomycin | 2003 |
In vitro activities of daptomycin, vancomycin, quinupristin- dalfopristin, linezolid, and five other antimicrobials against 307 gram-positive anaerobic and 31 Corynebacterium clinical isolates.
Topics: Acetamides; Anti-Bacterial Agents; Corynebacterium; Daptomycin; Gram-Positive Bacteria; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Vancomycin; Virginiamycin | 2003 |
In vitro bactericidal activities of linezolid in combination with vancomycin, gentamicin, ciprofloxacin, fusidic acid, and rifampin against Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Ciprofloxacin; Drug Combinations; Fusidic Acid; Gentamicins; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Rifampin; Staphylococcus aureus; Vancomycin | 2003 |
Linezolid versus vancomycin for methicillin-resistant Staphylococcus aureus infections.
Topics: Acetamides; Anti-Bacterial Agents; Health Care Costs; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2003 |
In vitro activity of linezolid alone and in combination with gentamicin, vancomycin or rifampicin against methicillin-resistant Staphylococcus aureus by time-kill curve methods.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotics, Antitubercular; Culture Media; Drug Combinations; Gentamicins; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Oxazolidinones; Rifampin; Staphylococcus aureus; Time Factors; Vancomycin | 2003 |
Impact of methicillin-resistant Staphylococcus aureus infections on key health economic outcomes: does reducing the length of hospital stay matter?
Topics: Acetamides; Anti-Bacterial Agents; Cost of Illness; Health Care Costs; Hospital Costs; Humans; Length of Stay; Linezolid; Methicillin Resistance; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2003 |
Linezolid and vancomycin, alone and in combination with rifampin, compared with moxifloxacin against a multidrug-resistant and a vancomycin-tolerant Streptococcus pneumoniae strain in an in vitro pharmacodynamic model.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Drug Tolerance; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Pneumococcal Infections; Rifampin; Streptococcus pneumoniae; Vancomycin; Vancomycin Resistance | 2003 |
Linezolid-resistant, vancomycin-resistant Enterococcus faecium infection in patients without prior exposure to linezolid.
Topics: Acetamides; Aged; Cross Infection; Enterococcus faecium; Female; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Microbial Sensitivity Tests; Oxazolidinones; Point Mutation; RNA, Ribosomal, 23S; Vancomycin; Vancomycin Resistance | 2003 |
In vitro activities of ramoplanin, teicoplanin, vancomycin, linezolid, bacitracin, and four other antimicrobials against intestinal anaerobic bacteria.
Topics: Acetamides; Actinomyces; Anti-Bacterial Agents; Bacitracin; Bacteria, Anaerobic; Clostridioides difficile; Depsipeptides; Eubacterium; Feces; In Vitro Techniques; Intestines; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Peptides, Cyclic; Peptostreptococcus; Propionibacterium; Teicoplanin; Vancomycin | 2003 |
In vitro and in vivo activities of novel 2-(thiazol-2-ylthio)-1beta-methylcarbapenems with potent activities against multiresistant gram-positive bacteria.
Topics: Abscess; Acetamides; Ampicillin Resistance; Animals; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Carrier Proteins; Dipeptidases; Drug Resistance, Multiple, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Hexosyltransferases; Kidney; Linezolid; Male; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Multienzyme Complexes; Muramoylpentapeptide Carboxypeptidase; Oxazolidinones; Penicillin-Binding Proteins; Peptidyl Transferases; Vancomycin; Vancomycin Resistance | 2003 |
Effect of linezolid on the phagocytic functions of human polymorphonuclear leukocytes.
Topics: Acetamides; Anti-Bacterial Agents; Blood Bactericidal Activity; Dose-Response Relationship, Drug; Enterococcus faecalis; Humans; Hydrogen Peroxide; In Vitro Techniques; Linezolid; Methicillin Resistance; Neutrophils; Oxazolidinones; Phagocytosis; Staphylococcus aureus; Superoxides; Vancomycin; Vancomycin Resistance | 2003 |
Liver abscess caused by an infected ventriculoperitoneal shunt: doubtful etiology and time for an alternative to vancomycin.
Topics: Acetamides; Anti-Bacterial Agents; Humans; Linezolid; Liver Abscess; Methicillin Resistance; Oxazolidinones; Prosthesis-Related Infections; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Vancomycin Resistance; Ventriculoperitoneal Shunt | 2003 |
Efficacy of linezolid alone or in combination with vancomycin for treatment of experimental endocarditis due to methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Aortic Valve; Colony Count, Microbial; Drug Synergism; Drug Therapy, Combination; Endocarditis, Bacterial; Female; Kidney; Linezolid; Macrolides; Methicillin Resistance; Oxazolidinones; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2003 |
Prophylactic efficacy of linezolid alone or combined with levofloxacin and vancomycin in a rat subcutaneous pouch model of graft infection caused by Staphylococcus epidermidis with intermediate resistance to glycopeptides.
Topics: Acetamides; Animals; Antibiotic Prophylaxis; Drug Resistance, Bacterial; Drug Therapy, Combination; Glycopeptides; Graft Rejection; Levofloxacin; Linezolid; Male; Microbial Sensitivity Tests; Ofloxacin; Oxazolidinones; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus epidermidis; Vancomycin | 2003 |
Linezolid compared with eperezolid, vancomycin, and gentamicin in an in vitro model of antimicrobial lock therapy for Staphylococcus epidermidis central venous catheter-related biofilm infections.
Topics: Acetamides; Anti-Infective Agents; Biofilms; Catheterization, Central Venous; Catheters, Indwelling; Colony Count, Microbial; Gentamicins; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Sodium Chloride; Staphylococcal Infections; Staphylococcus epidermidis; Vancomycin | 2003 |
Pharmacology of novel heteroaromatic polycycle antibacterials.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Area Under Curve; Bacterial Infections; Behavior, Animal; Calibration; Cation Transport Proteins; DNA; Dogs; Ether-A-Go-Go Potassium Channels; Female; Heterocyclic Compounds; Linezolid; Male; Mice; Mice, Inbred ICR; Muscle, Skeletal; Mutagens; Neutropenia; Oxazolidinones; Peritonitis; Pneumonia, Pneumococcal; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Binding; Rats; Rats, Sprague-Dawley; Tissue Distribution; Vancomycin | 2003 |
Nosocomial pneumonia: therapy is just not good enough.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Cross Infection; Humans; Intensive Care Units; Linezolid; Methicillin Resistance; Oxazolidinones; Pneumonia, Staphylococcal; Vancomycin | 2003 |
Linezolid vs vancomycin: analysis of two double-blind studies of patients with methicillin-resistant Staphylococcus aureus nosocomial pneumonia.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Cross Infection; Double-Blind Method; Female; Humans; Linezolid; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Pneumonia, Staphylococcal; Randomized Controlled Trials as Topic; Regression Analysis; Vancomycin | 2003 |
Delayed discovery of linezolid-resistant, vancomycin-resistant Enterococcus faecium: lessons learned.
Topics: Acetamides; Aged; Aged, 80 and over; Drug Resistance, Multiple, Bacterial; Enterococcus faecium; Female; Gram-Positive Bacterial Infections; Humans; Linezolid; Oxazolidinones; Vancomycin; Vancomycin Resistance | 2004 |
Linezolid, levofloxacin, and vancomycin against vancomycin-tolerant and fluoroquinolone-resistant Streptococcus pneumoniae in an in vitro pharmacodynamic model.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Ofloxacin; Oxazolidinones; Streptococcus pneumoniae; Vancomycin | 2003 |
Linezolid for treatment of ventilator-associated pneumonia: a cost-effective alternative to vancomycin.
Topics: Acetamides; Cohort Studies; Cost-Benefit Analysis; Drug Costs; Female; Hospital Costs; Humans; Intensive Care Units; Linezolid; Male; Oxazolidinones; Pneumonia, Aspiration; Pneumonia, Staphylococcal; Quality-Adjusted Life Years; Respiration, Artificial; Respiratory Distress Syndrome; United States; Vancomycin; Ventilators, Mechanical | 2004 |
Clinical cure and survival in Gram-positive ventilator-associated pneumonia: retrospective analysis of two double-blind studies comparing linezolid with vancomycin.
Topics: Acetamides; Adult; Aged; Anti-Infective Agents; Cross Infection; Female; Gram-Positive Bacterial Infections; Humans; Linezolid; Logistic Models; Male; Middle Aged; Oxazolidinones; Pneumonia, Bacterial; Respiration, Artificial; Retrospective Studies; Survival Analysis; Survival Rate; Vancomycin | 2004 |
Acute delirium associated with combined diphenhydramine and linezolid use.
Topics: Acetamides; Acute Disease; Delirium; Diphenhydramine; Drug Combinations; Drug Interactions; Duty to Warn; Hallucinations; Humans; Injections, Intravenous; Linezolid; Male; Middle Aged; Oxazolidinones; Pruritus; Risperidone; Time Factors; Vancomycin | 2004 |
[Sensitivity of methicillin resistant staphylococci to linezolid and some other antimicrobial agents].
Topics: Acetamides; Anti-Infective Agents; Ciprofloxacin; Clindamycin; Drug Resistance, Bacterial; Erythromycin; Gentamicins; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2003 |
Cost analysis of switching from i.v. vancomycin to p.o. linezolid for the management of methicillin-resistant Staphylococcus species.
Topics: Acetamides; Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Costs and Cost Analysis; Female; Hospitals, Veterans; Humans; Injections, Intravenous; Linezolid; Los Angeles; Male; Methicillin Resistance; Oxazolidinones; Staphylococcal Infections; Vancomycin | 2003 |
Treatment outcomes for serious infections caused by methicillin-resistant Staphylococcus aureus with reduced vancomycin susceptibility.
Topics: Acetamides; Aged; Aged, 80 and over; Anti-Infective Agents; Female; Humans; Linezolid; Male; Methicillin Resistance; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin; Vancomycin Resistance | 2004 |
Linezolid in VAP by MRSA: a better choice?
Topics: Acetamides; Anti-Infective Agents; Cross Infection; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Pneumonia, Staphylococcal; Respiration, Artificial; Vancomycin | 2004 |
In vitro post-antibiotic effect of fluoroquinolones, macrolides, beta-lactams, tetracyclines, vancomycin, clindamycin, linezolid, chloramphenicol, quinupristin/dalfopristin and rifampicin on Bacillus anthracis.
Topics: Acetamides; Anti-Bacterial Agents; Bacillus anthracis; beta-Lactams; Chloramphenicol; Clindamycin; Fluoroquinolones; Linezolid; Macrolides; Microbial Sensitivity Tests; Oxazolidinones; Rifampin; Tetracyclines; Vancomycin; Virginiamycin | 2004 |
Efficacy of dalbavancin against methicillin-resistant Staphylococcus aureus in the rat granuloma pouch infection model.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Female; Glycopeptides; Granuloma; Injections, Intramuscular; Injections, Intravenous; Linezolid; Male; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Rats; Rats, Sprague-Dawley; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Vancomycin | 2004 |
Comparative activity of telithromycin against macrolide-resistant isolates of Streptococcus pneumoniae: results of two years of the PROTEKT surveillance study.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Bacterial; Humans; Ketolides; Linezolid; Macrolides; Oxazolidinones; Pneumococcal Infections; Population Surveillance; Streptococcus pneumoniae; Vancomycin | 2004 |
Similar hematologic effects of long-term linezolid and vancomycin therapy in a prospective observational study of patients with orthopedic infections.
Topics: Acetamides; Adolescent; Adult; Aged; Anti-Infective Agents; Drug Combinations; Female; Gram-Positive Bacterial Infections; Hematologic Diseases; Humans; Linezolid; Male; Middle Aged; Orthopedics; Oxazolidinones; Postoperative Complications; Prospective Studies; Thrombocytopenia; Time; Vancomycin | 2004 |
Hematologic effects of linezolid versus vancomycin.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Hematologic Diseases; Humans; Linezolid; Oxazolidinones; Thrombocytopenia; Vancomycin | 2004 |
Successful treatment of disseminated cerebritis complicating methicillin-resistant Staphylococcus aureus Endocarditis unresponsive to vancomycin therapy with linezolid.
Topics: Acetamides; Bacteremia; Community-Acquired Infections; Dose-Response Relationship, Drug; Drug Resistance, Multiple, Bacterial; Endocarditis, Bacterial; Follow-Up Studies; Humans; Infusions, Intravenous; Linezolid; Male; Meningitis, Listeria; Methicillin Resistance; Middle Aged; Oxazolidinones; Risk Assessment; Severity of Illness Index; Staphylococcal Infections; Tomography, X-Ray Computed; Treatment Outcome; Vancomycin | 2004 |
Effects of linezolid on staphylococcal adherence versus time of treatment.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Adhesion; Cross Infection; Humans; In Vitro Techniques; Linezolid; Microscopy, Electron, Scanning; Oxazolidinones; Staphylococcal Infections; Staphylococcus epidermidis; Time Factors; Vancomycin | 2004 |
Unresolved questions with the use of linezolid vs vancomycin for nosocomial pneumonia.
Topics: Acetamides; Cross Infection; Female; Follow-Up Studies; Humans; Linezolid; Male; Oxazolidinones; Pneumonia, Bacterial; Risk Assessment; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2004 |
Linezolid and vancomycin for methicillin-resistant Staphylococcus aureus nosocomial pneumonia: the subtleties of subgroup analyses.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Cross Infection; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Pneumonia, Staphylococcal; Randomized Controlled Trials as Topic; Vancomycin | 2004 |
Pharmacodynamics of telavancin (TD-6424), a novel bactericidal agent, against gram-positive bacteria.
Topics: Acetamides; Aminoglycosides; Animals; Anti-Bacterial Agents; Area Under Curve; Dose-Response Relationship, Drug; Drug Resistance, Bacterial; Endpoint Determination; Female; Gram-Positive Bacterial Infections; Linezolid; Lipoglycopeptides; Methicillin Resistance; Mice; Muscle, Skeletal; Nafcillin; Neutropenia; Oxazolidinones; Protein Binding; Staphylococcal Infections; Subcutaneous Tissue; Vancomycin | 2004 |
Treatment of vancomycin-intermediate Staphylcoccus aureus endocarditis with linezolid.
Topics: Acetamides; Amikacin; Anti-Infective Agents; Aortic Valve; Drug Resistance, Bacterial; Drug Therapy, Combination; Endocarditis, Bacterial; Heart Valve Prosthesis; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Prosthesis-Related Infections; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin | 2004 |
Novel tetrahydro-thieno pyridyl oxazolidinone: an antibacterial agent.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Microbial; Enterococcus faecalis; Linezolid; Methicillin; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Pyridines; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin | 2004 |
Impact of high-inoculum Staphylococcus aureus on the activities of nafcillin, vancomycin, linezolid, and daptomycin, alone and in combination with gentamicin, in an in vitro pharmacodynamic model.
Topics: Acetamides; Anti-Bacterial Agents; Area Under Curve; Culture Media; Daptomycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Endocarditis, Bacterial; Gentamicins; Half-Life; Kinetics; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Nafcillin; Oxazolidinones; Penicillins; Staphylococcus aureus; Vancomycin | 2004 |
In vitro activities of cefotaxime, vancomycin, quinupristin/dalfopristin, linezolid and other antibiotics alone and in combination against Propionibacterium acnes isolates from central nervous system infections.
Topics: Acetamides; Cefotaxime; Central Nervous System Infections; Drug Therapy, Combination; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Propionibacterium acnes; Vancomycin; Virginiamycin | 2005 |
In vitro activity of vancomycin, quinupristin/dalfopristin, and linezolid against intact and disrupted biofilms of staphylococci.
Topics: Acetamides; Biofilms; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus; Staphylococcus aureus; Staphylococcus epidermidis; Vancomycin; Virginiamycin | 2005 |
First linezolid- and vancomycin-resistant Enterococcus faecium strain in Taiwan.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Enterococcus faecium; Female; Gram-Positive Bacterial Infections; Humans; Linezolid; Middle Aged; Oxazolidinones; Taiwan; Vancomycin | 2005 |
No mercy for MRSA: treatment alternatives to vancomycin and linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Cross Infection; Humans; Liability, Legal; Linezolid; Methicillin Resistance; Oxazolidinones; Rifampin; Staphylococcal Infections; Staphylococcus aureus; United States; Vancomycin | 2005 |
Ventriculitis due to a hetero strain of vancomycin intermediate Staphylococcus aureus (hVISA): successful treatment with linezolid in combination with intraventricular vancomycin.
Topics: Acetamides; Aged; Cerebral Ventricles; Drug Resistance, Bacterial; Drug Therapy, Combination; Encephalitis; Humans; Linezolid; Male; Oxazolidinones; South Africa; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2005 |
Susceptibility of methicillin-resistant Staphylococcus aureus to vancomycin, teicoplanin, linezolid, pristinamycin and other antibiotics.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Pristinamycin; Staphylococcus aureus; Teicoplanin; Vancomycin | 2005 |
Antibacterial activity of linezolid and vancomycin in an in vitro pharmacodynamic model of gram-positive catheter-related bacteraemia.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Biofilms; Catheterization, Central Venous; Colony Count, Microbial; Enterococcus faecium; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Linezolid; Microbial Sensitivity Tests; Models, Biological; Oxazolidinones; Staphylococcus aureus; Staphylococcus epidermidis; Vancomycin | 2005 |
Coagulase-negative staphylococcal meningitis in adults: clinical characteristics and therapeutic outcomes.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Female; Humans; Linezolid; Male; Meningitis, Bacterial; Middle Aged; Oxacillin; Oxazolidinones; Penicillin Resistance; Retrospective Studies; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2005 |
Methicillin-resistant Staphylococcus aureus infection in liver transplantation: a matched controlled study.
Topics: Acetamides; Female; Humans; Incidence; Intensive Care Units; Length of Stay; Linezolid; Liver Transplantation; Male; Methicillin Resistance; Oxazolidinones; Postoperative Complications; Retrospective Studies; Staphylococcal Infections; Survival Analysis; Vancomycin | 2005 |
In vitro activity of daptomycin versus linezolid and vancomycin against gram-positive uropathogens and ampicillin against enterococci, causing complicated urinary tract infections.
Topics: Acetamides; Ampicillin; Anti-Bacterial Agents; Cross Infection; Daptomycin; Enterococcus; Genotype; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus; Urinary Tract Infections; Vancomycin | 2005 |
Synthesis and antibacterial activity of novel (un)substituted benzotriazolyl oxazolidinone derivatives.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; In Vitro Techniques; Linezolid; Methicillin; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Structure-Activity Relationship; Vancomycin | 2005 |
Cost-effectiveness analysis of the treatment of ventilator-associated pneumonia with linezolid or vancomycin in Spain.
Topics: Acetamides; Cost Savings; Cost-Benefit Analysis; Economics, Pharmaceutical; Female; Health Care Costs; Humans; Linezolid; Male; National Health Programs; Oxazolidinones; Pneumonia, Bacterial; Randomized Controlled Trials as Topic; Respiration, Artificial; Retrospective Studies; Spain; Survival Analysis; Treatment Outcome; Vancomycin | 2005 |
Effects of daptomycin, linezolid, and vancomycin on establishment of intestinal colonization with vancomycin-resistant enterococci and extended-spectrum-beta-lactamase-producing Klebsiella pneumoniae in mice.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; beta-Lactamases; Daptomycin; Enterococcus; Female; Humans; Intestines; Klebsiella pneumoniae; Linezolid; Mice; Microbial Sensitivity Tests; Oxazolidinones; Vancomycin; Vancomycin Resistance | 2005 |
Comparative efficacies of quinupristin-dalfopristin, linezolid, vancomycin, and ciprofloxacin in treatment, using the antibiotic-lock technique, of experimental catheter-related infection due to Staphylococcus aureus.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Catheters, Indwelling; Ciprofloxacin; Disease Models, Animal; Drug Therapy, Combination; Linezolid; Male; Oxazolidinones; Plankton; Rats; Rats, Wistar; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin; Virginiamycin | 2005 |
Cost-effectiveness of linezolid versus vancomycin in mechanical ventilation-associated nosocomial pneumonia caused by methicillin-resistant staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Cost-Benefit Analysis; Cross Infection; Drug Costs; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Pneumonia, Staphylococcal; Respiration, Artificial; Staphylococcus aureus; Vancomycin | 2005 |
Improved outcomes with linezolid for methicillin-resistant Staphylococcus aureus infections: better drug or reduced vancomycin susceptibility?
Topics: Acetamides; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Skin Diseases, Bacterial; Soft Tissue Infections; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2005 |
Treatment failure of methicillin-resistant Staphylococcus aureus endocarditis with linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Endocarditis, Bacterial; Fatal Outcome; Humans; Linezolid; Male; Methicillin Resistance; Middle Aged; Mitral Valve; Oxazolidinones; Recurrence; Staphylococcal Infections; Staphylococcus aureus; Treatment Failure; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2005 |
Measurement of ampicillin, vancomycin, linezolid and gentamicin activity against enterococcal biofilms.
Topics: Acetamides; Ampicillin; Anti-Bacterial Agents; Bacteremia; Biofilms; Catheterization, Central Venous; Enterococcus faecalis; Enterococcus faecium; Gentamicins; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Vancomycin | 2006 |
Successful treatment with linezolid and rifampicin of meningitis due to methicillin-resistant Staphylococcus epidermidis refractory to vancomycin treatment.
Topics: Acetamides; Anti-Bacterial Agents; Drug Therapy, Combination; Female; Humans; Linezolid; Meningitis, Bacterial; Methicillin Resistance; Middle Aged; Oxazolidinones; Rifampin; Staphylococcal Infections; Staphylococcus epidermidis; Treatment Outcome; Vancomycin | 2006 |
Is linezolid superior to vancomycin for complicated skin and soft tissue infections due to methicillin-resistant Staphylococcus aureus?
Topics: Acetamides; Anti-Bacterial Agents; Clinical Trials as Topic; Drug Resistance, Microbial; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Soft Tissue Infections; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin | 2006 |
Central venous catheter colonization by linezolid-resistant, vancomycin-susceptible Enterococcus faecalis.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Bacteremia; Catheterization, Central Venous; Drug Resistance, Bacterial; Enterococcus faecalis; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Oxazolidinones; Vancomycin | 2006 |
What can we learn from studies comparing linezolid with vancomycin in neutropenic patients when vancomycin dosages are not optimized?
Topics: Acetamides; Anti-Bacterial Agents; Fever; Humans; Linezolid; Neutropenia; Oxazolidinones; Vancomycin | 2006 |
Clearance of linezolid via continuous venovenous hemodiafiltration.
Topics: Acetamides; Acute Kidney Injury; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Drug Resistance, Bacterial; Fasciitis, Necrotizing; Hemofiltration; Humans; Linezolid; Male; Metabolic Clearance Rate; Oxazolidinones; Time Factors; Urinary Tract Infections; Vancomycin | 2006 |
A holistic approach to MRSA eradication in critically ill patients with MRSA pneumonia.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Critical Illness; Cross Infection; Drug Utilization; Female; Humans; Infection Control; Intensive Care Units; Linezolid; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Pneumonia, Staphylococcal; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin | 2006 |
Impact of selective antimicrobial agents on staphylococcal adherence to biomedical devices.
Topics: Acetamides; Anti-Bacterial Agents; Biofilms; Blood Vessel Prosthesis; Ceftriaxone; Daptomycin; Gentamicins; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Rifampin; Staphylococcus; Vancomycin | 2006 |
The clinical impact of linezolid susceptibility reporting in patients with vancomycin-resistant enterococci.
Topics: Academic Medical Centers; Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Cohort Studies; Cross Infection; Disease Susceptibility; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Enterococcus faecium; Female; Gram-Positive Bacterial Infections; Humans; Length of Stay; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Retrospective Studies; Treatment Outcome; Vancomycin; Vancomycin Resistance | 2006 |
Nosocomial spread of Enterococcus faecium resistant to vancomycin and linezolid in a tertiary care medical center.
Topics: Academic Medical Centers; Acetamides; Adult; Aged; Aged, 80 and over; Alabama; Anti-Infective Agents; Cross Infection; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Vancomycin; Vancomycin Resistance | 2006 |
Cost-effectiveness analysis of linezolid compared with vancomycin for the treatment of nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Cost-Benefit Analysis; Cross Infection; Female; Health Care Costs; Humans; Linezolid; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Pneumonia, Staphylococcal; Randomized Controlled Trials as Topic; Staphylococcus aureus; Vancomycin | 2006 |
Efficacy of high doses of levofloxacin in experimental foreign-body infection by methicillin-susceptible Staphylococcus aureus.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cloxacillin; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Foreign-Body Reaction; Humans; Levofloxacin; Linezolid; Male; Methicillin; Microbial Sensitivity Tests; Ofloxacin; Oxazolidinones; Rats; Rats, Wistar; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2006 |
Efficacy of linezolid versus vancomycin in the treatment of methicillin-resistant Staphylococcus aureus discitis: a controlled animal model.
Topics: Acetamides; Animals; Discitis; Disease Models, Animal; Linezolid; Methicillin Resistance; Oxazolidinones; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2006 |
High-level vancomycin-resistant Staphylococcus aureus isolates associated with a polymicrobial biofilm.
Topics: Acetamides; Aminoglycosides; Biofilms; Catheters, Indwelling; Chloramphenicol; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Enterococcus faecium; Female; Fluoroquinolones; Humans; Linezolid; Macrolides; Microbial Sensitivity Tests; Micrococcus; Middle Aged; Morganella morganii; Oxazolidinones; Penicillins; Pseudomonas aeruginosa; Rifampin; Staphylococcus aureus; Tetracyclines; Trimethoprim, Sulfamethoxazole Drug Combination; Urinary Catheterization; Vancomycin; Vancomycin Resistance | 2007 |
In vitro activity of linezolid in combination with doxycycline, fosfomycin, levofloxacin, rifampicin and vancomycin against methicillin-susceptible Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Doxycycline; Drug Therapy, Combination; Enzyme Inhibitors; Fosfomycin; Humans; In Vitro Techniques; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Ofloxacin; Oxazolidinones; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2006 |
Staphylococcus aureus biofilm as a target for single or repeated doses of oxacillin, vancomycin, linezolid and/or lysostaphin.
Topics: Acetamides; Anti-Bacterial Agents; Biofilms; Drug Therapy, Combination; Humans; Linezolid; Lysostaphin; Microbial Sensitivity Tests; Microscopy, Confocal; Oxacillin; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2006 |
Reactivation of dormant lumbar methicillin-resistant Staphylococcus aureus osteomyelitis after 12 years.
Topics: Abscess; Acetamides; Adult; Anti-Bacterial Agents; Bacteremia; Debridement; Drug Therapy, Combination; Humans; Intervertebral Disc Displacement; Laminectomy; Linezolid; Lumbar Vertebrae; Male; Methicillin Resistance; Osteomyelitis; Oxazolidinones; Recurrence; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Time Factors; Treatment Outcome; Vancomycin | 2007 |
Impact of antibiotics on expression of virulence-associated exotoxin genes in methicillin-sensitive and methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bacterial Toxins; Clindamycin; Enterotoxins; Exotoxins; Hemolysin Proteins; Leukocidins; Linezolid; Methicillin; Methicillin Resistance; Microbial Sensitivity Tests; Nafcillin; Oxazolidinones; Protein Synthesis Inhibitors; Rabbits; Staphylococcus aureus; Superantigens; Vancomycin; Virulence | 2007 |
Bactericidal activity of daptomycin, vancomycin, teicoplanin and linezolid against Staphylococcus aureus, Enterococcus faecalis and Enterococcus faecium using human peak free serum drug concentrations.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; In Vitro Techniques; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus; Teicoplanin; Vancomycin | 2007 |
Antistaphylococcal activity of DX-619 alone and in combination with vancomycin, teicoplanin, and linezolid assessed by time-kill synergy testing.
Topics: Acetamides; Anti-Bacterial Agents; Drug Synergism; Drug Therapy, Combination; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Pyrrolidines; Quinolones; Staphylococcus aureus; Teicoplanin; Time Factors; Vancomycin | 2007 |
Economic evaluation of linezolid versus vancomycin in mechanical ventilation-associated nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Infective Agents; Cost-Benefit Analysis; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Pneumonia, Staphylococcal; Pneumonia, Ventilator-Associated; Staphylococcus aureus; Vancomycin | 2006 |
The economic effect of oral linezolid versus intravenous vancomycin in the outpatient setting: the payer perspective.
Topics: Acetamides; Adult; Ambulatory Care; Anti-Bacterial Agents; Anti-Infective Agents; Female; Humans; Injections, Intravenous; Insurance Claim Review; Linezolid; Male; Managed Care Programs; Middle Aged; Oxazolidinones; Vancomycin | 2007 |
In vitro activity of antimicrobial agents against oxacillin resistant staphylococci with special reference to Staphylococcus haemolyticus.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; India; Linezolid; Microbial Sensitivity Tests; Oxacillin; Oxazolidinones; Staphylococcus; Staphylococcus haemolyticus; Teicoplanin; Vancomycin; Virginiamycin | 2007 |
In vitro efficacy and pharmacodynamic indices for antibiotics against coagulase-negative staphylococcus endophthalmitis isolates.
Topics: Acetamides; Administration, Oral; Administration, Topical; Anti-Bacterial Agents; Aqueous Humor; Aza Compounds; Biological Availability; Coagulase; Endophthalmitis; Eye Infections, Bacterial; Fluoroquinolones; Gatifloxacin; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Microbiological Techniques; Moxifloxacin; Oxazolidinones; Quinolines; Staphylococcal Infections; Staphylococcus; Vancomycin; Virginiamycin | 2007 |
[Appropriate use of anti-MRSA drugs (discussion)].
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Community-Acquired Infections; Cross Infection; Dibekacin; Humans; Immunocompromised Host; Linezolid; Methicillin Resistance; Oxazolidinones; Practice Guidelines as Topic; Staphylococcus aureus; Teicoplanin; Vancomycin | 2007 |
Methicillin-resistant Staphylococcus aureus pneumonia after thoracic surgery: successful treatment with linezolid after failed vancomycin therapy.
Topics: Acetamides; Aged; Aged, 80 and over; Anti-Infective Agents; Cross Infection; Female; Humans; Linezolid; Male; Methicillin Resistance; Oxazolidinones; Pneumonia, Staphylococcal; Staphylococcus aureus; Thoracic Surgical Procedures; Treatment Failure; Treatment Outcome; Vancomycin | 2007 |
Cost-effectiveness analysis of linezolid compared with vancomycin for the treatment of nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Cost-Benefit Analysis; Cross Infection; Decision Support Techniques; Dose-Response Relationship, Drug; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Pneumonia, Staphylococcal; Randomized Controlled Trials as Topic; Research Design; Retrospective Studies; Staphylococcus aureus; Survival Rate; Vancomycin | 2007 |
Cost-effectiveness analysis of linezolid compared with vancomycin for the treatment of nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Cost-Benefit Analysis; Cross Infection; Disclosure; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Peer Review, Research; Pneumonia, Staphylococcal; Research Design; Staphylococcus aureus; Vancomycin | 2007 |
[Vancomycin resistant enterococci in etiology of neutropenic enterocolitis: prophylaxis, clinical signs and treatment].
Topics: Acetamides; Adolescent; Adult; Anti-Infective Agents; Antineoplastic Agents; Drug Resistance, Bacterial; Enterococcus; Enterocolitis; Feces; Gram-Positive Bacterial Infections; Hematologic Neoplasms; Hemorrhage; Humans; Linezolid; Middle Aged; Neutropenia; Oxazolidinones; Vancomycin | 2006 |
Detection of vancomycin heteroresistant Staphylococcus haemolyticus and vancomycin intermediate resistant Staphylococcus epidermidis by means of vancomycin screening agar.
Topics: Acetamides; Acute Disease; Adult; Agar; Anti-Bacterial Agents; Bone Marrow Transplantation; Drug Resistance; Humans; Immunocompromised Host; Leukemia, Myeloid; Linezolid; Male; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Staphylococcus epidermidis; Staphylococcus haemolyticus; Vancomycin | 2007 |
A comparison of costs and hospital length of stay associated with intravenous/oral linezolid or intravenous vancomycin treatment of complicated skin and soft-tissue infections caused by suspected or confirmed methicillin-resistant Staphylococcus aureus in
Topics: Acetamides; Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Health Care Costs; Hospitalization; Humans; Injections, Intravenous; Length of Stay; Linezolid; Male; Methicillin Resistance; Oxazolidinones; Soft Tissue Infections; Staphylococcal Skin Infections; Staphylococcus aureus; United States; Vancomycin | 2007 |
Early switch from vancomycin to oral linezolid for treatment of gram-positive heart valve endocarditis.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Drug Resistance, Bacterial; Endocarditis, Bacterial; Female; Gram-Positive Bacterial Infections; Health Care Costs; Heart Valve Diseases; Heart Valve Prosthesis; Humans; Length of Stay; Linezolid; Male; Middle Aged; Oxazolidinones; Retrospective Studies; Vancomycin | 2007 |
Cost-effectiveness analysis of linezolid compared with vancomycin for the treatment of nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Cost-Benefit Analysis; Cross Infection; Humans; Linezolid; Methicillin Resistance; Oxazolidinones; Pneumonia, Staphylococcal; Staphylococcus aureus; Vancomycin | 2007 |
Vancomycin MIC creep in non-vancomycin-intermediate Staphylococcus aureus (VISA), vancomycin-susceptible clinical methicillin-resistant S. aureus (MRSA) blood isolates from 2001-05.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxacillin; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Time Factors; Vancomycin | 2007 |
Linezolid versus vancomycin for prosthetic joint infections: a cost analysis.
Topics: Acetamides; Administration, Oral; Algorithms; Anti-Bacterial Agents; Costs and Cost Analysis; Gram-Positive Bacterial Infections; Health Care Costs; Home Care Services; Humans; Infusions, Intravenous; Joint Prosthesis; Linezolid; Methicillin Resistance; Oxazolidinones; Prosthesis-Related Infections; Vancomycin | 2007 |
Gut overgrowth of vancomycin-resistant enterococci (VRE) results in linezolid-resistant mutation in a child with severe congenital neutropenia: a case report.
Topics: Acetamides; Anti-Bacterial Agents; Child; Drug Resistance, Multiple, Bacterial; Enterococcus; Humans; Intestines; Linezolid; Mutation; Neutropenia; Oxazolidinones; Protein Synthesis Inhibitors; Stem Cell Transplantation; Streptococcal Infections; Vancomycin; Vancomycin Resistance | 2007 |
Effects of tigecycline, linezolid and vancomycin on biofilms of viridans streptococci isolates from patients with endocarditis.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Biofilms; Dose-Response Relationship, Drug; Endocarditis, Bacterial; Female; Heart Valve Prosthesis; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Oxazolidinones; Prosthesis-Related Infections; Streptococcal Infections; Tigecycline; Treatment Outcome; Vancomycin; Viridans Streptococci | 2007 |
Linezolid- and vancomycin-resistant Enterococcus faecium endocarditis: successful treatment with tigecycline and daptomycin.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Endocarditis, Bacterial; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Middle Aged; Minocycline; Oxazolidinones; Tigecycline; Treatment Outcome; Vancomycin | 2007 |
Preseptal cellulitis caused by community acquired methicillin resistant Staphylococcus aureus (CAMRSA).
Topics: Acetamides; Administration, Oral; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Community-Acquired Infections; Drug Therapy, Combination; Football; Humans; Linezolid; Male; Methicillin Resistance; Ophthalmic Solutions; Orbital Cellulitis; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2007 |
Update on prevalence and treatment of methicillin-resistant Staphylococcus aureus infections.
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Cephalosporins; Clindamycin; Daptomycin; Doxycycline; Folic Acid Antagonists; Global Health; Glycopeptides; Humans; Linezolid; Lipoglycopeptides; Methicillin; Methicillin Resistance; Minocycline; Oxazolidinones; Prevalence; Staphylococcal Infections; Staphylococcus aureus; Sulfamethoxazole; Teicoplanin; Tigecycline; Trimethoprim; Vancomycin | 2007 |
Comparative bactericidal activities of daptomycin, glycopeptides, linezolid and tigecycline against blood isolates of Gram-positive bacteria in Taiwan.
Topics: Acetamides; Anti-Infective Agents; Daptomycin; Drug Resistance, Bacterial; Drug Therapy, Combination; Glycopeptides; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Linezolid; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Staphylococcus aureus; Streptococcaceae; Taiwan; Teicoplanin; Tigecycline; Time Factors; Vancomycin | 2008 |
Pharmacodynamic comparison of linezolid, teicoplanin and vancomycin against clinical isolates of Staphylococcus aureus and coagulase-negative staphylococci collected from hospitals in Brazil.
Topics: Acetamides; Anti-Infective Agents; Area Under Curve; Brazil; Coagulase; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Models, Biological; Monte Carlo Method; Oxazolidinones; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Teicoplanin; Vancomycin | 2008 |
Linezolid for treatment of subdural empyema due to Streptococcus: case reports.
Topics: Acetamides; Adolescent; Anti-Bacterial Agents; Brain Neoplasms; Drainage; Empyema, Subdural; Facial Injuries; Female; Humans; Linezolid; Magnetic Resonance Imaging; Male; Middle Aged; Mydriasis; Neurosurgical Procedures; Oxazolidinones; Paresis; Seizures; Streptococcal Infections; Subdural Space; Vancomycin | 2009 |
A comparative in-vitro evaluation of resistance selection after exposure to teicoplanin, vancomycin, linezolid and quinupristin-dalfopristin in Staphylococcus aureus and Enterococcus spp.
Topics: Acetamides; Anti-Bacterial Agents; Colony Count, Microbial; Drug Resistance, Bacterial; Enterococcus faecalis; Enterococcus faecium; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Mutation; Oxazolidinones; Selection, Genetic; Staphylococcus aureus; Teicoplanin; Vancomycin; Virginiamycin | 2008 |
Activities of clindamycin, daptomycin, doxycycline, linezolid, trimethoprim-sulfamethoxazole, and vancomycin against community-associated methicillin-resistant Staphylococcus aureus with inducible clindamycin resistance in murine thigh infection and in vi
Topics: Acetamides; Animals; Anti-Bacterial Agents; Clindamycin; Colony Count, Microbial; Community-Acquired Infections; Culture Media; Daptomycin; Disease Models, Animal; Doxycycline; Drug Resistance, Bacterial; Humans; Linezolid; Methicillin Resistance; Mice; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Thigh; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2008 |
Molecular characterisation of linezolid resistance in two vancomycin-resistant (VanB) Enterococcus faecium isolates using Pyrosequencing.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterococcus faecium; Female; Genes, Bacterial; Genes, rRNA; Gram-Positive Bacterial Infections; Humans; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Linezolid; Microbial Sensitivity Tests; Mucositis; Oxazolidinones; Pancreatitis, Acute Necrotizing; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Sequence Analysis, DNA; Vancomycin; Vancomycin Resistance | 2008 |
Cost-effectiveness of linezolid versus vancomycin for hospitalised patients with complicated skin and soft-tissue infections in Germany.
Topics: Acetamides; Anti-Bacterial Agents; Cost-Benefit Analysis; Decision Support Techniques; Delphi Technique; Germany; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Soft Tissue Infections; Staphylococcal Skin Infections; Vancomycin | 2009 |
Efficacy and pharmacodynamics of linezolid, alone and in combination with rifampicin, in an experimental model of methicillin-resistant Staphylococcus aureus endocarditis.
Topics: Acetamides; Administration, Oral; Animals; Anti-Bacterial Agents; Drug Therapy, Combination; Endocarditis, Bacterial; Heart Valves; Kidney; Linezolid; Liver; Lung; Male; Methicillin Resistance; Microbial Sensitivity Tests; Microbial Viability; Models, Animal; Oxazolidinones; Plasma; Rabbits; Rifampin; Spleen; Staphylococcal Infections; Staphylococcus aureus; Survival Analysis; Vancomycin | 2008 |
Effect of sub-MIC concentrations of metronidazole, vancomycin, clindamycin and linezolid on toxin gene transcription and production in Clostridium difficile.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Clindamycin; Clostridioides difficile; Enterotoxins; Gene Expression Regulation, Bacterial; Humans; Linezolid; Metronidazole; Microbial Sensitivity Tests; Oxazolidinones; Polymerase Chain Reaction; Time Factors; Transcription, Genetic; Vancomycin | 2008 |
Noncardiogenic pulmonary edema in a patient receiving vancomycin and oxycodone-acetaminophen.
Topics: Acetamides; Acetaminophen; Analgesics; Anti-Infective Agents; Cellulitis; Diphenhydramine; Drug Combinations; Famotidine; Furosemide; Humans; Linezolid; Male; Methicillin Resistance; Middle Aged; Oxazolidinones; Oxycodone; Pulmonary Edema; Staphylococcal Skin Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin | 2008 |
Empiric antibiotic therapy for acute osteoarticular infections with suspected methicillin-resistant Staphylococcus aureus or Kingella.
Topics: Acetamides; Acute Disease; Anti-Bacterial Agents; Arthritis, Infectious; Child, Preschool; Decision Trees; Humans; Infant; Kingella; Linezolid; Methicillin Resistance; Neisseriaceae Infections; Osteomyelitis; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2008 |
Effect of oxazolidinone, RBx 7644 (ranbezolid), on inhibition of staphylococcal adherence to plastic surfaces.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Dose-Response Relationship, Drug; Furans; Linezolid; Microbial Sensitivity Tests; Oxazoles; Oxazolidinones; Plastics; Staphylococcus aureus; Staphylococcus epidermidis; Time Factors; Vancomycin; Virginiamycin | 2008 |
Reduction in rates of methicillin-resistant Staphylococcus aureus infection after introduction of quarterly linezolid-vancomycin cycling in a surgical intensive care unit.
Topics: Acetamides; Anti-Bacterial Agents; Drug Administration Schedule; Enterococcus; General Surgery; Gram-Positive Bacterial Infections; Humans; Intensive Care Units; Linezolid; Methicillin Resistance; Middle Aged; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin | 2008 |
Lack of increase in time to blood culture positivity in a patient with persistent methicillin-resistant Staphylococcus aureus bacteremia predicts failure of antimicrobial therapy.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Bacteremia; Blood; Catheters, Indwelling; Female; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Staphylococcal Infections; Time Factors; Treatment Failure; Vancomycin | 2008 |
Bacteriostatic or bactericidal effect of linezolid against multiresistant Streptococcus pneumoniae.
Topics: Acetamides; Anti-Bacterial Agents; Child, Preschool; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Penicillin Resistance; Phylogeny; Polymerase Chain Reaction; Streptococcus pneumoniae; Vancomycin | 2008 |
Comparison of the therapeutic efficacy of linezolid and vancomycin and correlation of serum and tissue malondialdehyde and myeloperoxidase in an experimental mediastinitis model.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Disease Models, Animal; Linezolid; Male; Malondialdehyde; Mediastinitis; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Peroxidase; Rats; Rats, Wistar; Vancomycin | 2009 |
Efficacy of telavancin in the treatment of methicillin-resistant Staphylococcus aureus osteomyelitis: studies with a rabbit model.
Topics: Acetamides; Aminoglycosides; Animals; Anti-Bacterial Agents; Bone Marrow; Colony Count, Microbial; Linezolid; Lipoglycopeptides; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Osteomyelitis; Oxazolidinones; Rabbits; Random Allocation; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2009 |
Hyperbaric oxygen as adjunctive therapy in experimental mediastinitis.
Topics: Acetamides; Animals; Anti-Infective Agents; Combined Modality Therapy; Hyperbaric Oxygenation; Linezolid; Male; Mediastinitis; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Rats; Rats, Wistar; Staphylococcal Infections; Teicoplanin; Vancomycin | 2009 |
Characterisation of a Staphylococcus aureus strain with progressive loss of susceptibility to vancomycin and daptomycin during therapy.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Daptomycin; Drug Resistance, Bacterial; Endocarditis, Bacterial; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin; Virginiamycin | 2009 |
Cost-effectiveness of linezolid vs vancomycin in suspected methicillin-resistant Staphylococcus aureus nosocomial pneumonia in Germany.
Topics: Acetamides; Anti-Bacterial Agents; Cost-Benefit Analysis; Cross Infection; Decision Support Techniques; Drug Costs; Female; Germany; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Models, Economic; Oxazolidinones; Pneumonia, Staphylococcal; Retrospective Studies; Vancomycin | 2009 |
Anti-MRSA activity of aldehyde Schiff base N-aryl thiosemicarbazones.
Topics: Acetamides; Aldehydes; Anti-Infective Agents; Drug Resistance, Bacterial; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Schiff Bases; Staphylococcal Infections; Thiosemicarbazones; Vancomycin | 2009 |
Drug use density in critically ill children and newborns: analysis of various methodologies.
Topics: Acetamides; Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Critical Illness; Drug Administration Schedule; Drug Utilization Review; Humans; Infant; Intensive Care Units, Pediatric; Intensive Care, Neonatal; Linezolid; Oxazolidinones; Retrospective Studies; Vancomycin | 2009 |
Bacteremia caused by an Enterococcus faecalis isolate with high-level linezolid resistance in a teenager with Crohn's disease.
Topics: Acetamides; Adolescent; Anti-Bacterial Agents; Bacteremia; Crohn Disease; Drug Resistance, Bacterial; Enterococcus faecalis; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Microbial Sensitivity Tests; Oxazolidinones; Treatment Outcome; Vancomycin | 2009 |
Successful salvage therapy with daptomycin after linezolid and vancomycin failure in a liver transplant recipient with methicillin-resistant Staphylococcus aureus endocarditis.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Cross Infection; Daptomycin; Endocarditis, Bacterial; Humans; Linezolid; Liver Transplantation; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Salvage Therapy; Staphylococcal Infections; Treatment Failure; Treatment Outcome; Vancomycin | 2009 |
Recurrent cellulitis in a case of Aagenaes syndrome.
Topics: Acetamides; Adolescent; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Cellulitis; Cholestasis, Intrahepatic; Humans; Ketorolac; Linezolid; Lower Extremity; Lymphedema; Male; Oxazolidinones; Recurrence; Syndrome; Vancomycin | 2009 |
Colonization of the tip of a thoracic catheter by Enterococcus faecalis resistant to vancomycin and linezolid.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Catheterization; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Staphylococcal Infections; Vancomycin | 2009 |
Bone tissue and plasma concentrations of linezolid and vancomycin in rabbits with prosthesis-related infection due to MRSA.
Topics: Acetamides; Animals; Anti-Infective Agents; Bone and Bones; Chromatography, High Pressure Liquid; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Prosthesis-Related Infections; Rabbits; Spectrophotometry, Ultraviolet; Vancomycin | 2009 |
Evaluating aztreonam and ceftazidime pharmacodynamics with Escherichia coli in combination with daptomycin, linezolid, or vancomycin in an in vitro pharmacodynamic model.
Topics: Acetamides; Anti-Bacterial Agents; Aztreonam; Ceftazidime; Daptomycin; Drug Synergism; Drug Therapy, Combination; Escherichia coli; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Vancomycin | 2009 |
In vitro 24-hour time-kill studies of vancomycin and linezolid in combination versus methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Drug Antagonism; Drug Synergism; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Vancomycin | 2009 |
Use of a sensitive chemiluminescence-based assay to evaluate the metabolic suppression activity of linezolid on methicillin-resistant Staphylococcus aureus showing reduced susceptibility to vancomycin.
Topics: Acetamides; Anti-Bacterial Agents; Humans; Linezolid; Luminescent Measurements; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microbial Viability; Oxazolidinones; Protein Synthesis Inhibitors; Staphylococcal Infections; Vancomycin; Vancomycin Resistance | 2009 |
Community-acquired methicillin-resistant Staphylococcus aureus and Lemierre syndrome.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Community-Acquired Infections; Daptomycin; Female; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Sepsis; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2009 |
Linezolid-associated acute interstitial nephritis and drug rash with eosinophilia and systemic symptoms (DRESS) syndrome.
Topics: Acetamides; Acute Disease; Aged, 80 and over; Anti-Infective Agents; Eosinophilia; Exanthema; Female; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Nephritis, Interstitial; Oxazolidinones; Prosthesis-Related Infections; Staphylococcal Infections; Syndrome; Vancomycin | 2009 |
Inpatient treatment patterns, outcomes, and costs of skin and skin structure infections because of Staphylococcus aureus.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Daptomycin; Drug Utilization; Drug Utilization Review; Female; Humans; Inpatients; Length of Stay; Linezolid; Male; Middle Aged; Oxazolidinones; Retrospective Studies; Staphylococcal Skin Infections; Treatment Outcome; Vancomycin; Young Adult | 2010 |
A refractory case of community-acquired pneumonia.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Asthma; Community-Acquired Infections; Critical Illness; Drug Resistance, Bacterial; Drug Therapy, Combination; Emergency Service, Hospital; Female; Follow-Up Studies; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Oxygen Inhalation Therapy; Pneumonia, Staphylococcal; Radiography, Thoracic; Recurrence; Risk Assessment; Sputum; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2009 |
Observational studies of salvage treatment for persistent bacteremia: beware of survivor treatment selection bias.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Drug Therapy, Combination; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Salvage Therapy; Staphylococcal Infections; Vancomycin | 2009 |
Vancomycin-resistant Enterococcus spp.: validation of susceptibility testing and in vitro activity of vancomycin, linezolid, tigecycline and daptomycin.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bacterial Proteins; Carbon-Oxygen Ligases; Daptomycin; DNA, Bacterial; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Polymerase Chain Reaction; Reproducibility of Results; Tigecycline; Vancomycin; Vancomycin Resistance | 2010 |
Incidence of vancomycin-resistant enterococci (VRE) infection in high-risk febrile neutropenic patients colonized with VRE.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Case-Control Studies; Ciprofloxacin; Daptomycin; Enterococcus; Female; Fever; Humans; Incidence; Linezolid; Male; Middle Aged; Neutropenia; Oxazolidinones; Retrospective Studies; Vancomycin; Vancomycin Resistance | 2010 |
Analysis of methods commonly used for glycopeptide and oxazolidinone susceptibility testing in Enterococcus faecium isolates.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; Carbon-Oxygen Ligases; DNA, Bacterial; Enterococcus faecium; Glycopeptides; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; RNA, Ribosomal, 23S; Teicoplanin; Vancomycin | 2010 |
MRSA--too many hurdles to overcome: a study from Central India.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Cefoxitin; Drug Resistance, Multiple, Bacterial; Humans; Incidence; India; Inhibitory Concentration 50; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Prevalence; Staphylococcal Infections; Vancomycin | 2010 |
In vitro evaluation of ceftaroline alone and in combination with tobramycin against hospital-acquired meticillin-resistant Staphylococcus aureus (HA-MRSA) isolates.
Topics: Acetamides; Ceftaroline; Cephalosporins; Cross Infection; Daptomycin; Drug Synergism; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Tobramycin; Vancomycin | 2010 |
Impregnation of bone chips with antibiotics and storage of antibiotics at different temperatures: an in vitro study.
Topics: Acetamides; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bone Transplantation; Cefazolin; Clindamycin; Dose-Response Relationship, Drug; Drug Compounding; Drug Stability; Drug Storage; Humans; Linezolid; Microbial Sensitivity Tests; Oxacillin; Oxazolidinones; Prosthesis-Related Infections; Staphylococcus epidermidis; Surgical Wound Infection; Temperature; Transplantation, Homologous; Vancomycin | 2010 |
Hospital policies and practices on prevention and treatment of infections caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Clinical Protocols; Daptomycin; Formularies, Hospital as Topic; Guidelines as Topic; Health Care Surveys; Hospitals; Humans; Infection Control; Linezolid; Methicillin-Resistant Staphylococcus aureus; Minocycline; Organizational Policy; Oxazolidinones; Patient Isolation; Pharmacy Service, Hospital; Staphylococcal Infections; Surveys and Questionnaires; Tigecycline; Vancomycin | 2010 |
Efficacy of the new cephalosporin ceftaroline in the treatment of experimental methicillin-resistant Staphylococcus aureus acute osteomyelitis.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bone and Bones; Bone Marrow; Ceftaroline; Cephalosporins; Disease Models, Animal; Female; Linezolid; Methicillin-Resistant Staphylococcus aureus; Osteomyelitis; Oxazolidinones; Rabbits; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2010 |
Ecthyma gangrenosum mimicking acute invasive fungal sinusitis in an immunocompromised patient.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Diagnosis, Differential; Ecthyma; Humans; Immunocompromised Host; Linezolid; Male; Mycoses; Nasal Mucosa; Ofloxacin; Oxazolidinones; Protein Synthesis Inhibitors; Pseudomonas aeruginosa; Pseudomonas Infections; Pyoderma Gangrenosum; Risk Factors; Sinusitis; Vancomycin | 2010 |
[Comparative study of the susceptibility to daptomycin and other antimicrobials against Staphylococcus spp. resistant to methicillin and Enterococcus spp. using Wider, E-test, and microdilution methods].
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Enterococcus; Humans; Linezolid; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Teicoplanin; Vancomycin | 2010 |
Catheter-related bacteremia caused by methicillin-resistant coagulase negative staphylococci with elevated minimal inhibitory concentration for vancomycin.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Catheterization, Central Venous; Catheters, Indwelling; Chi-Square Distribution; Child; Coagulase; Daptomycin; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Prospective Studies; Staphylococcus; Vancomycin | 2010 |
Comparative effectiveness of linezolid and vancomycin among a national cohort of patients infected with methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Aged; Anti-Infective Agents; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2010 |
In vitro and in vivo activities of linezolid alone and combined with vancomycin and imipenem against Staphylococcus aureus with reduced susceptibility to glycopeptides.
Topics: Acetamides; Animals; Ascitic Fluid; Bacteremia; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Synergism; Drug Therapy, Combination; Glycopeptides; Imipenem; Linezolid; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Oxazolidinones; Peritonitis; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2010 |
Penetration of linezolid into rabbit intervertebral discs and surrounding tissues.
Topics: Acetamides; Animals; Anti-Infective Agents; Chromatography, High Pressure Liquid; Fluorescence Polarization Immunoassay; Intervertebral Disc; Linezolid; Male; Oxazolidinones; Rabbits; Staphylococcus aureus; Vancomycin | 2010 |
[Vancomycin, what else?].
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Child; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2010 |
Comparison of antimicrobial agents as therapy for experimental endocarditis: caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Animals; Anti-Infective Agents; Aortic Valve; Colony Count, Microbial; Disease Models, Animal; Endocarditis, Bacterial; Infusions, Intravenous; Injections, Intravenous; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Rats; Rats, Wistar; Teicoplanin; Time Factors; Vancomycin; Virginiamycin | 2010 |
Efficacy of fosfomycin and its combination with linezolid, vancomycin and imipenem in an experimental peritonitis model caused by a Staphylococcus aureus strain with reduced susceptibility to vancomycin.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Ascitic Fluid; Bacteremia; Bacterial Load; Disease Models, Animal; Drug Therapy, Combination; Female; Fosfomycin; Humans; Imipenem; Linezolid; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Oxazolidinones; Peritonitis; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2011 |
What is MRSA?
Topics: Acetamides; Anti-Bacterial Agents; Community-Acquired Infections; Cross Infection; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Staphylococcal Infections; Vancomycin | 2010 |
Severe ventilator-associated pneumonia caused by methicillin-resistant Staphylococcus aureus and other pathogens: report of a case successfully managed by serial surveillance cultures of endotracheal aspirates.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Bronchoalveolar Lavage; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Pneumonia, Ventilator-Associated; Respiratory Distress Syndrome; Staphylococcal Infections; Vancomycin | 2011 |
Diminished in vitro antibacterial activity of oxacillin against clinical isolates of borderline oxacillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Daptomycin; Drug Resistance, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Oxacillin; Oxazolidinones; Penicillin Resistance; Penicillin-Binding Proteins; Plasmids; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2010 |
Efficacy of usual and high doses of daptomycin in combination with rifampin versus alternative therapies in experimental foreign-body infection by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Daptomycin; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Rats; Rats, Wistar; Rifampin; Staphylococcal Infections; Vancomycin | 2010 |
Comparative activity of telavancin and other antimicrobial agents against methicillin-resistant Staphylococcus aureus isolates collected from 1991 to 2006.
Topics: Acetamides; Aminoglycosides; Anti-Infective Agents; Daptomycin; Linezolid; Lipoglycopeptides; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Tigecycline; Vancomycin | 2010 |
Treatment of meningitis caused by vancomycin-resistant Enterococcus faecium: high-dose and combination daptomycin therapy.
Topics: Acetamides; Aged; Daptomycin; Drug Therapy, Combination; Enterococcus faecium; Gentamicins; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Meningitis, Bacterial; Middle Aged; Oxazolidinones; Vancomycin; Vancomycin Resistance | 2010 |
The role of diabetes mellitus in the treatment of skin and skin structure infections caused by methicillin-resistant Staphylococcus aureus: results from three randomized controlled trials.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Diabetes Complications; Diabetic Foot; Female; Humans; Length of Stay; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Prospective Studies; Randomized Controlled Trials as Topic; Staphylococcal Skin Infections; Treatment Outcome; Vancomycin | 2011 |
Comparison of the pharmacokinetic properties of vancomycin, linezolid, tigecyclin, and daptomycin.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Humans; Linezolid; Minocycline; Oxazolidinones; Tigecycline; Vancomycin | 2010 |
Treatment with linezolid or vancomycin in combination with rifampin is effective in an animal model of methicillin-resistant Staphylococcus aureus foreign body osteomyelitis.
Topics: Acetamides; Animals; Foreign Bodies; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Osteomyelitis; Oxazolidinones; Rats; Rats, Wistar; Rifampin; Vancomycin | 2011 |
Impact of administration of vancomycin or linezolid to critically ill patients with impaired renal function.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Creatinine; Critical Illness; Female; Gram-Positive Bacterial Infections; Humans; Kidney; Linezolid; Male; Metabolic Clearance Rate; Middle Aged; Oxazolidinones; Renal Insufficiency; Retrospective Studies; Vancomycin | 2011 |
Susceptibility patterns of coagulase-negative staphylococci to several newer antimicrobial agents in comparison with vancomycin and oxacillin.
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Bacterial Proteins; Daptomycin; DNA, Ribosomal; Linezolid; Lipoglycopeptides; Microbial Sensitivity Tests; Micrococcal Nuclease; Minocycline; Oxacillin; Oxazolidinones; Penicillin-Binding Proteins; Polymerase Chain Reaction; Staphylococcus; Tigecycline; Vancomycin | 2011 |
Comparison of in vitro efficacy of linezolid and vancomycin by determining their minimum inhibitory concentrations against methicillin resistant Staphylococcus aureus (MRSA).
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; Hospitals, Military; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Vancomycin | 2011 |
Comparative in vitro activity of telavancin, vancomycin and linezolid against heterogeneously vancomycin-intermediate Staphylococcus aureus (hVISA).
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Humans; Linezolid; Lipoglycopeptides; Microbial Sensitivity Tests; Microbial Viability; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Time Factors; Vancomycin; Vancomycin Resistance | 2011 |
In vitro activity of linezolid, tigecycline, and daptomycin on methicillin-resistant Staphylococcus aureus blood isolates from adult patients, 2006-2008: stratified analysis by vancomycin MIC.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Bacteremia; Blood; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Staphylococcal Infections; Taiwan; Tigecycline; Vancomycin | 2011 |
Does linezolid modulate lung innate immunity in a murine model of methicillin-resistant Staphylococcus aureus pneumonia?
Topics: Acetamides; Analysis of Variance; Animals; Anti-Infective Agents; Apoptosis; Confidence Intervals; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Female; Immunity, Innate; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Neutrophils; Oxazolidinones; Peroxidase; Pneumonia, Staphylococcal; Random Allocation; Survival Rate; Treatment Outcome; Vancomycin | 2011 |
In vitro efficacy of antimicrobial agents against high-inoculum or biofilm-embedded meticillin-resistant Staphylococcus aureus with vancomycin minimal inhibitory concentrations equal to 2 μg/mL (VA2-MRSA).
Topics: Acetamides; Anti-Infective Agents; Biofilms; Drug Synergism; Drug Therapy, Combination; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Stem Cells; Tigecycline; Vancomycin | 2011 |
Diagnosis and management of community-acquired pneumonia in adults.
Topics: Acetamides; Adult; Anti-Bacterial Agents; Anti-Infective Agents; beta-Lactams; Community-Acquired Infections; Diagnosis, Differential; Doxycycline; Drug Therapy, Combination; Fluoroquinolones; Humans; Influenza Vaccines; Linezolid; Macrolides; Oxazolidinones; Pneumococcal Vaccines; Pneumonia, Bacterial; Practice Guidelines as Topic; Risk Factors; Treatment Outcome; United States; Vancomycin | 2011 |
Activity of vancomycin, ciprofloxacin, daptomycin, and linezolid against coagulase-negative staphylococci bacteremia.
Topics: Acetamides; Bacteremia; Catheter-Related Infections; Ciprofloxacin; Cross Infection; Daptomycin; Drug Resistance, Multiple, Bacterial; Hospital Departments; Hospitals, University; Humans; Length of Stay; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Spain; Staphylococcal Infections; Staphylococcus epidermidis; Staphylococcus haemolyticus; Staphylococcus hominis; Vancomycin | 2011 |
[Microbial spectrum of nosocomial pneumonia in traumatological patients].
Topics: Acetamides; Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bacteria; Carbapenems; Cross Infection; Drug Resistance, Microbial; Escherichia coli; Female; Hospitals; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Pneumonia, Bacterial; Pseudomonas aeruginosa; Staphylococcus aureus; Streptococcus pneumoniae; Vancomycin; Wounds and Injuries | 2011 |
Is linezolid a risk factor for Gram-negative bacillus infections in intensive care unit patients? A comparative study with vancomycin.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Comorbidity; Cross Infection; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Humans; Intensive Care Units; Length of Stay; Linezolid; Male; Middle Aged; Oxazolidinones; Renal Insufficiency; Retrospective Studies; Risk Factors; Vancomycin | 2011 |
Activity of ceftaroline and epidemiologic trends in Staphylococcus aureus isolates collected from 43 medical centers in the United States in 2009.
Topics: Acetamides; Bacterial Toxins; Ceftaroline; Cephalosporins; Clindamycin; Daptomycin; Electrophoresis, Gel, Pulsed-Field; Erythromycin; Exotoxins; Leukocidins; Levofloxacin; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mupirocin; Ofloxacin; Oxacillin; Oxazolidinones; Polymerase Chain Reaction; Staphylococcus aureus; Tetracycline; Trimethoprim, Sulfamethoxazole Drug Combination; United States; Vancomycin | 2011 |
Linezolid does not show advantages over vancomycin in modulating the pulmonary immune response: how should we conciliate these new findings with the Zephyr trial results?
Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Clinical Trials as Topic; Disease Models, Animal; Humans; Immunity, Innate; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Oxazolidinones; Pneumonia, Staphylococcal; Risk Assessment; Treatment Outcome; Vancomycin | 2011 |
Implant stability in the treatment of MRSA bone implant infections with linezolid versus vancomycin in a rabbit model.
Topics: Acetamides; Animals; Anti-Infective Agents; Biomechanical Phenomena; Female; Femur; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Prostheses and Implants; Prosthesis-Related Infections; Rabbits; Staphylococcal Infections; Titanium; Vancomycin | 2012 |
The MUT056399 inhibitor of FabI is a new antistaphylococcal compound.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Benzamides; Drug Resistance, Multiple, Bacterial; Enoyl-(Acyl-Carrier-Protein) Reductase (NADH); Escherichia coli; Escherichia coli Proteins; Fatty Acid Synthase, Type II; Female; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Mutation; Oxazolidinones; Phenyl Ethers; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2011 |
Telavancin for the treatment of methicillin-resistant Staphylococcus aureus osteomyelitis.
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Daptomycin; Humans; Linezolid; Lipoglycopeptides; Methicillin-Resistant Staphylococcus aureus; Minocycline; Osteomyelitis; Oxazolidinones; Staphylococcal Infections; Tigecycline; Vancomycin | 2011 |
Successful therapy of treatment-emergent, non-clonal daptomycin-non-susceptible Enterococcus faecium infections.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Oxazolidinones; Vancomycin | 2011 |
[Actual aspects of sepsis].
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Carbapenems; Cefepime; Cephalosporins; Drug Resistance, Microbial; Enterobacteriaceae; Female; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Hospitals; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Retrospective Studies; Russia; Sepsis; Vancomycin | 2011 |
Efficacy of linezolid compared to vancomycin in an experimental model of pneumonia induced by methicillin-resistant Staphylococcus aureus in ventilated pigs.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Disease Models, Animal; Interleukin-6; Interleukin-8; Linezolid; Lung; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Pneumonia, Ventilator-Associated; Respiration, Artificial; Swine; Tumor Necrosis Factor-alpha; Vancomycin | 2012 |
[In vitro susceptibility of methicillin-resistant Staphylococcus aureus isolates to vancomycin, teicoplanin, linezolide and daptomycin].
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Teicoplanin; Vancomycin | 2011 |
[Pharmacoeconomic assessment of daptomycin as first-line therapy for bacteraemia and complicated skin and skin structure infections caused by gram-positive pathogens in Spain].
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cost-Benefit Analysis; Daptomycin; Data Interpretation, Statistical; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Hospitals; Humans; Linezolid; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Oxazolidinones; Salvage Therapy; Skin Diseases, Infectious; Spain; Treatment Failure; Vancomycin; Young Adult | 2011 |
Time-kill study and synergistic activity of cell-wall inhibitor antibiotics in combination with gentamicin against Enterococcus faecalis and Enterococcus faecium.
Topics: Acetamides; Ampicillin; Anti-Bacterial Agents; Bacterial Proteins; Carbon-Oxygen Ligases; Drug Synergism; Enterococcus faecalis; Enterococcus faecium; Gentamicins; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Teicoplanin; Vancomycin | 2011 |
Antibiotic modulation of the plasminogen binding ability of viridans group streptococci.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; Endocarditis, Bacterial; Fibrinolysin; Gene Expression Regulation, Bacterial; Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+); Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Penicillins; Phosphopyruvate Hydratase; Plasminogen; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Species Specificity; Streptococcal Infections; Streptococcus mitis; Streptococcus oralis; Streptococcus sanguis; Vancomycin | 2012 |
Simulated antibiotic exposures in an in vitro hollow-fiber infection model influence toxin gene expression and production in community-associated methicillin-resistant Staphylococcus aureus strain MW2.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Cell Culture Techniques; Clindamycin; Community-Acquired Infections; Enzyme-Linked Immunosorbent Assay; Exotoxins; Gene Expression Regulation, Bacterial; Humans; Leukocidins; Leukocytes, Mononuclear; Linezolid; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Models, Biological; Oxazolidinones; Real-Time Polymerase Chain Reaction; Staphylococcal Infections; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin; Virulence Factors | 2012 |
[Influence of inoculum size on MICs for methicillin-susceptible Staphylococcus aureus and methicillin-resistant Staphylococcus aureus].
Topics: Acetamides; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents; Bacteriological Techniques; Cefazolin; Ciprofloxacin; Dibekacin; Drug Resistance, Bacterial; Linezolid; Meropenem; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus; Teicoplanin; Thienamycins; Vancomycin | 2011 |
[Case of meningitis caused by group B Streptococcus treated with high dose of meropenem].
Topics: Acetamides; Aged; Anti-Bacterial Agents; Drug Therapy, Combination; Humans; Linezolid; Male; Meningitis, Bacterial; Meropenem; Oxazolidinones; Pulse Therapy, Drug; Serotyping; Streptococcal Infections; Streptococcus agalactiae; Thienamycins; Treatment Outcome; Vancomycin | 2011 |
Vancomycin-resistant Enterococcus bacteremia: an evaluation of treatment with linezolid or daptomycin.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Daptomycin; Enterococcus faecalis; Female; Humans; Immunocompromised Host; Linezolid; Male; Middle Aged; Outcome Assessment, Health Care; Oxazolidinones; Retrospective Studies; United States; Vancomycin; Vancomycin Resistance | 2012 |
[Evaluation of vancomycin, teicoplanin, linezolide and tigecycline susceptibilities of nosocomial methicillin-resistant Staphylococcus strains by E-test].
Topics: Acetamides; Anti-Bacterial Agents; Cross Infection; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Staphylococcal Infections; Teicoplanin; Tigecycline; Turkey; Vancomycin | 2011 |
Activity of tigecycline and comparators against skin and skin structure pathogens: global results of the Tigecycline evaluation and surveillance trial, 2004-2009.
Topics: Acetamides; Acinetobacter baumannii; Carbapenems; Drug Evaluation; Drug Resistance, Bacterial; Enterococcus faecalis; Enterococcus faecium; Humans; Klebsiella pneumoniae; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Skin; Skin Diseases, Bacterial; Tigecycline; Vancomycin | 2012 |
[Antibiotic susceptibility of isolates from blood of patients in intensive care units of emergency medical service].
Topics: Acetamides; Anti-Bacterial Agents; Bacteria, Anaerobic; Bacterial Infections; Candida; Cross Infection; Drug Resistance, Microbial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imipenem; Infection Control; Intensive Care Units; Linezolid; Meropenem; Moscow; Oxazolidinones; Sepsis; Thienamycins; Vancomycin | 2011 |
[Antibiotic resistance dynamics and isolation rate of staphylococci and enterococci from patients of reconstructive surgery units].
Topics: Acetamides; Amoxicillin; Anti-Bacterial Agents; Cefoxitin; Cross Infection; Drug Resistance, Microbial; Enterococcus; Fluoroquinolones; Fusidic Acid; Gram-Positive Bacterial Infections; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Moscow; Oxacillin; Oxazolidinones; Rifampin; Surgery, Plastic; Vancomycin | 2011 |
A comparative evaluation of adverse platelet outcomes among Veterans' Affairs patients receiving linezolid or vancomycin.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Blood Platelets; Cohort Studies; Humans; Incidence; Linezolid; Male; Middle Aged; New York; Oxazolidinones; Thrombocytopenia; Treatment Outcome; Vancomycin | 2012 |
Vancomycin for methicillin-resistant Staphylococcus aureus pneumonia: the good, the bad, and the ugly.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Pneumonia, Ventilator-Associated; Vancomycin | 2012 |
Comparative in vivo efficacies of epithelial lining fluid exposures of tedizolid, linezolid, and vancomycin for methicillin-resistant Staphylococcus aureus in a mouse pneumonia model.
Topics: Acetamides; Administration, Oral; Animals; Anti-Bacterial Agents; Colony Count, Microbial; Disease Models, Animal; Drug Administration Schedule; Female; Humans; Injections, Intravenous; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Oxazolidinones; Pneumonia, Staphylococcal; Survival Rate; Tetrazoles; Vancomycin | 2012 |
Pharmacokinetic-pharmacodynamic evaluation of daptomycin, tigecycline, and linezolid versus vancomycin for the treatment of MRSA infections in four western European countries.
Topics: Acetamides; Anti-Bacterial Agents; Belgium; Daptomycin; Ireland; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Spain; Staphylococcal Infections; Tigecycline; United Kingdom; Vancomycin | 2012 |
Action of linezolid or vancomycin on biofilms in ventriculoperitoneal shunts in vitro.
Topics: Acetamides; Biofilms; Cerebrospinal Fluid Shunts; Drug Resistance, Bacterial; Enterococcus faecalis; Enterococcus faecium; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus; Staphylococcus epidermidis; Vancomycin | 2012 |
Direct analysis of bacterial viability in endotracheal tube biofilm from a pig model of methicillin-resistant Staphylococcus aureus pneumonia following antimicrobial therapy.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Biofilms; Disease Models, Animal; Equipment and Supplies; Intubation, Intratracheal; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Viability; Microscopy, Confocal; Oxazolidinones; Placebos; Pneumonia, Staphylococcal; Spain; Staining and Labeling; Swine; Vancomycin | 2012 |
Evaluation of standard- and high-dose daptomycin versus linezolid against vancomycin-resistant Enterococcus isolates in an in vitro pharmacokinetic/pharmacodynamic model with simulated endocardial vegetations.
Topics: Acetamides; Daptomycin; Endocarditis, Bacterial; Enterococcus; Enterococcus faecalis; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Vancomycin | 2012 |
[Activity of vancomycin, teicoplanin and linezolid in methicillin resistant coagulase-negative Staphylococci isolates from paediatric blood cultures].
Topics: Acetamides; Anti-Bacterial Agents; Child; Child, Preschool; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Female; Humans; Infant; Infant, Newborn; Linezolid; Male; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Polymerase Chain Reaction; Staphylococcal Infections; Staphylococcus; Staphylococcus epidermidis; Staphylococcus hominis; Teicoplanin; Vancomycin | 2012 |
[Analysis of treatments used in infections caused by gram-positive multiresistant cocci in critically ill patients admitted to the ICU].
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Cohort Studies; Critical Care; Critical Illness; Daptomycin; Drug Prescriptions; Drug Resistance, Multiple, Bacterial; Drug Utilization; Female; Gram-Positive Bacterial Infections; Gram-Positive Cocci; Humans; Intensive Care Units; Linezolid; Male; Middle Aged; Oxazolidinones; Retrospective Studies; Teicoplanin; Vancomycin | 2012 |
Efficacy of linezolid versus a pharmacodynamically optimized vancomycin therapy in an experimental pneumonia model caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bacterial Load; Disease Models, Animal; Female; Linezolid; Lung; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred C57BL; Oxazolidinones; Pneumonia, Staphylococcal; Treatment Outcome; Vancomycin | 2012 |
Probable linezolid-induced thrombocytopenia in a patient with vancomycin-resistant enterococci.
Topics: Acetamides; Aged; Anti-Infective Agents; Blood Platelets; Enterococcus; Humans; Linezolid; Male; Oxazolidinones; Platelet Count; Risk Factors; Thrombocytopenia; Vancomycin; Vancomycin Resistance; White People | 2012 |
Bactericidal activity of ACH-702 against nondividing and biofilm Staphylococci.
Topics: Acetamides; Anti-Bacterial Agents; Aza Compounds; Biofilms; Fluoroquinolones; Linezolid; Microbial Sensitivity Tests; Molecular Structure; Moxifloxacin; Oxazolidinones; Quinolines; Quinolones; Rifampin; Staphylococcus; Thiazoles; Vancomycin | 2012 |
Elimination of teicoplanin by adsorption to the filter membrane during haemodiafiltration: screening experiments for linezolid, teicoplanin and vancomycin followed by in vitro haemodiafiltration models for teicoplanin.
Topics: Acetamides; Adsorption; Albumins; Algorithms; Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Filtration; Hemodiafiltration; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Models, Biological; Oxazolidinones; Staphylococcal Infections; Teicoplanin; Vancomycin | 2012 |
Emergence of vancomycin-resistant Enterococcus bloodstream infections in southern Taiwan.
Topics: Acetamides; Aged; Aged, 80 and over; Analysis of Variance; Anti-Bacterial Agents; Bacteremia; Daptomycin; Enterococcus; Female; Gram-Positive Bacterial Infections; Hospitals, University; Humans; Incidence; Linezolid; Male; Middle Aged; Oxazolidinones; Proportional Hazards Models; Retrospective Studies; Risk Factors; Taiwan; Vancomycin; Vancomycin Resistance | 2012 |
In vitro activities of LTX-109, a synthetic antimicrobial peptide, against methicillin-resistant, vancomycin-intermediate, vancomycin-resistant, daptomycin-nonsusceptible, and linezolid-nonsusceptible Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Multiple, Bacterial; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oligopeptides; Oxazolidinones; Vancomycin; Vancomycin Resistance | 2012 |
Linezolid limits burden of methicillin-resistant Staphylococcus aureus in biofilm of tracheal tubes.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Biofilms; Intubation, Intratracheal; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microscopy, Electron, Scanning; Oxazolidinones; Pneumonia, Staphylococcal; Pneumonia, Ventilator-Associated; Swine; Vancomycin | 2012 |
Efficacy of intravitreal administrations of linezolid in an experimental model of S. aureus-related endophthalmitis.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Disease Models, Animal; Electroretinography; Endophthalmitis; Female; Intravitreal Injections; Linezolid; Oxazolidinones; Rabbits; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin; Vitreous Body | 2012 |
Pharmacodynamics of early, high-dose linezolid against vancomycin-resistant enterococci with elevated MICs and pre-existing genetic mutations.
Topics: Acetamides; Anti-Bacterial Agents; Colony Count, Microbial; Enterococcus faecalis; Humans; Linezolid; Microbial Sensitivity Tests; Microbial Viability; Models, Theoretical; Mutation; Oxazolidinones; Time Factors; Vancomycin; Vancomycin Resistance | 2012 |
Treatment of methicillin-resistant Staphylococcus aureus ventilator-associated pneumonia with high-dose vancomycin or linezolid.
Topics: Acetamides; Adult; Aged; Cohort Studies; Critical Illness; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Injury Severity Score; Intensive Care Units; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Pneumonia, Ventilator-Associated; Respiration, Artificial; Retrospective Studies; Risk Assessment; Severity of Illness Index; Staphylococcal Infections; Survival Rate; Trauma Centers; Treatment Outcome; Vancomycin; Wounds and Injuries | 2012 |
Risk factors and outcomes associated with vancomycin-resistant Enterococcus infections with reduced susceptibilities to linezolid.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Case-Control Studies; Drug Resistance, Bacterial; Enterococcus; Female; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Retrospective Studies; Risk Factors; Treatment Outcome; Vancomycin; Young Adult | 2012 |
Clinical efficacy of oral linezolid compared with intravenous vancomycin for the treatment of methicillin-resistant Staphylococcus aureus-complicated skin and soft tissue infections: a retrospective, propensity score-matched, case-control analysis.
Topics: Acetamides; Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Clinical Trials, Phase IV as Topic; Female; Humans; Infusions, Intravenous; Linezolid; Logistic Models; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Multicenter Studies as Topic; Odds Ratio; Oxazolidinones; Propensity Score; Randomized Controlled Trials as Topic; Retrospective Studies; Soft Tissue Infections; Staphylococcal Skin Infections; Treatment Outcome; Vancomycin | 2012 |
Usefulness of SBA-15 mesoporous ceramics as a delivery system for vancomycin, rifampicin and linezolid: a preliminary report.
Topics: Acetamides; Anti-Bacterial Agents; Bacillus subtilis; Biological Assay; Ceramics; Chromatography, High Pressure Liquid; Drug Carriers; Drug Delivery Systems; Linezolid; Micrococcaceae; Oxazolidinones; Rifampin; Silicon Dioxide; Vancomycin | 2012 |
Surgical site infection prophylaxis strategies for cardiothoracic surgery: a decision-analytic model.
Topics: Acetamides; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Cefuroxime; Humans; Incidence; Linezolid; Oxazolidinones; Preoperative Care; Surgical Wound Infection; Survival Analysis; Thoracic Surgical Procedures; United States; Vancomycin | 2012 |
Linezolid is superior to vancomycin in experimental pneumonia caused by Superantigen-Producing staphylococcus aureus in HLA class II transgenic mice.
Topics: Acetamides; Animals; Linezolid; Mice; Mice, Inbred BALB C; Mice, Transgenic; Oxazolidinones; Pneumonia, Bacterial; Staphylococcal Infections; Staphylococcus aureus; Superantigens; Vancomycin | 2012 |
Empiric antibiotics pending bronchoalveolar lavage data in patients without pneumonia significantly alters the flora, but not the resistance profile, if a subsequent pneumonia develops.
Topics: Acetamides; Anti-Bacterial Agents; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Cefepime; Cephalosporins; Drug Resistance, Bacterial; Drug Therapy, Combination; Female; Gram-Negative Bacteria; Gram-Negative Bacterial Infections; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Penicillanic Acid; Piperacillin; Pneumonia, Ventilator-Associated; Retrospective Studies; Tazobactam; Treatment Outcome; Vancomycin; Wounds and Injuries | 2013 |
Vancomycin versus linezolid in the treatment of methicillin-resistant Staphylococcus aureus nosocomial pneumonia: implications of the ZEPHyR trial.
Topics: Acetamides; Anti-Bacterial Agents; Cross Infection; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Vancomycin | 2012 |
[Evaluation of antibiotic susceptibilities and VISA-VRSA rates among MRSA strains isolated from hospitalized patients in intensive care units of hospitals in seven provinces of Turkey].
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Humans; Intensive Care Units; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Staphylococcal Infections; Teicoplanin; Tigecycline; Turkey; Vancomycin; Vancomycin Resistance; Virginiamycin | 2012 |
[Microbiological monitoring in therapy of patients with iatrogenic esophageotracheal fistula].
Topics: Acetamides; Anti-Bacterial Agents; Candida; Cefepime; Cephalosporins; Ciprofloxacin; Drug Resistance, Microbial; Enterobacteriaceae; Follow-Up Studies; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Iatrogenic Disease; Imipenem; Intubation, Intratracheal; Linezolid; Microbial Sensitivity Tests; Monitoring, Physiologic; Oxazolidinones; Polymyxin B; Pseudomonas aeruginosa; Respiratory Tract Infections; Staphylococcus aureus; Staphylococcus epidermidis; Tracheoesophageal Fistula; Vancomycin | 2012 |
Vancomycin versus linezolid in the treatment of methicillin-resistant Staphylococcus aureus meningitis in an experimental rabbit model.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Colony Count, Microbial; Disease Models, Animal; Linezolid; Meningitis, Bacterial; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Rabbits; Staphylococcal Infections; Vancomycin | 2012 |
Empiric therapy directed against MRSA in patients admitted to the intensive care unit does not improve outcomes in community-acquired pneumonia.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Community-Acquired Infections; Comorbidity; Empirical Research; Female; Hospital Mortality; Humans; Intensive Care Units; Length of Stay; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Pneumonia, Bacterial; Prevalence; Proportional Hazards Models; Retrospective Studies; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2013 |
Activity of ceftaroline against extracellular (broth) and intracellular (THP-1 monocytes) forms of methicillin-resistant Staphylococcus aureus: comparison with vancomycin, linezolid and daptomycin.
Topics: Acetamides; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Monocytes; Oxazolidinones; Vancomycin | 2013 |
Predictors and outcomes of linezolid-resistant vancomycin-resistant Enterococcus: a case-case-control study.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Case-Control Studies; Drug Resistance, Bacterial; Enterococcus; Female; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Risk Factors; Treatment Outcome; Vancomycin | 2012 |
In vivo bioluminescence imaging to evaluate systemic and topical antibiotics against community-acquired methicillin-resistant Staphylococcus aureus-infected skin wounds in mice.
Topics: Acetamides; Administration, Oral; Administration, Topical; Animals; Anti-Bacterial Agents; Bacterial Load; Bridged Bicyclo Compounds, Heterocyclic; Clindamycin; Community-Acquired Infections; Daptomycin; Diabetes Mellitus, Type 2; Disease Models, Animal; Diterpenes; Doxycycline; Linezolid; Luminescent Measurements; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred C57BL; Mupirocin; Oxazolidinones; Skin; Soft Tissue Infections; Staphylococcal Infections; Staphylococcal Skin Infections; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin; Wound Healing | 2013 |
Treatment of methicillin-resistant Staphylococcus aureus infections with a minimal inhibitory concentration of 2 μg/mL to vancomycin: old (trimethoprim/sulfamethoxazole) versus new (daptomycin or linezolid) agents.
Topics: Acetamides; Adult; Age Factors; Aged; Anti-Bacterial Agents; Cohort Studies; Cost Savings; Daptomycin; Drug Costs; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Multivariate Analysis; Oxazolidinones; Retrospective Studies; Severity of Illness Index; Staphylococcal Infections; Time Factors; Treatment Outcome; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2012 |
Fosfomycin synergy in vitro with amoxicillin, daptomycin, and linezolid against vancomycin-resistant Enterococcus faecium from renal transplant patients with infected urinary stents.
Topics: Acetamides; Amoxicillin; Anti-Bacterial Agents; Daptomycin; Drug Synergism; Enterococcus faecium; Fosfomycin; Gram-Positive Bacterial Infections; Humans; Kidney Transplantation; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Stents; Urinary Tract; Urinary Tract Infections; Vancomycin; Vancomycin Resistance | 2013 |
Inoculum effects of ceftobiprole, daptomycin, linezolid, and vancomycin with Staphylococcus aureus and Streptococcus pneumoniae at inocula of 10(5) and 10(7) CFU injected into opposite thighs of neutropenic mice.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Cephalosporins; Colony Count, Microbial; Daptomycin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Injections, Subcutaneous; Linezolid; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Neutropenia; Oxazolidinones; Pneumococcal Infections; Staphylococcal Infections; Staphylococcus aureus; Streptococcus pneumoniae; Thigh; Vancomycin | 2013 |
Methicillin-resistant Staphylococcus aureus-induced thrombo-inflammatory response is reduced with timely antibiotic administration.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Blood Coagulation; Cell-Derived Microparticles; Cytokines; Drug Administration Schedule; Humans; Inflammation; Inflammation Mediators; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred C57BL; Monocytes; Oxazolidinones; Sepsis; Staphylococcal Infections; Thrombin; Thrombosis; Time Factors; Vancomycin | 2013 |
Improved outcome of ventilator-associated pneumonia caused by methicillin-resistant Staphylococcus aureus in a trauma population.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Infective Agents; Bronchoalveolar Lavage; Female; Humans; Intensive Care Units; Length of Stay; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Pneumonia, Staphylococcal; Pneumonia, Ventilator-Associated; Retrospective Studies; Treatment Outcome; Vancomycin; Wounds, Nonpenetrating | 2013 |
Anti-inflammatory, anti-coagulant, anti-biotic?
Topics: Acetamides; Animals; Anti-Bacterial Agents; Humans; Inflammation; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Sepsis; Staphylococcal Infections; Thrombosis; Vancomycin | 2013 |
Effect of linezolid on clinical severity and pulmonary cytokines in a murine model of influenza A and Staphylococcus aureus coinfection.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bacterial Load; Coinfection; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Humans; Immunologic Factors; Influenza A virus; Influenza, Human; Interleukins; Linezolid; Lung; Mice; Mice, Inbred C57BL; Oxazolidinones; Severity of Illness Index; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Viral Load; Weight Loss | 2013 |
Spectrum of gram-positive bacteraemia and in vitro activities of daptomycin, linezolid and vancomycin against organisms isolated from cancer patients.
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Child; Child, Preschool; Daptomycin; Female; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Neoplasms; Oxazolidinones; Prevalence; Vancomycin; Young Adult | 2013 |
Sccmec type II gene is common among clinical isolates of methicillin-resistant Staphylococcus aureus in Jakarta, Indonesia.
Topics: Acetamides; Amikacin; Clindamycin; Community-Acquired Infections; Cross Infection; DNA Primers; Drug Resistance, Multiple, Bacterial; Genes, Bacterial; Humans; Indonesia; Linezolid; Methicillin-Resistant Staphylococcus aureus; Minocycline; Oxazolidinones; Plasmids; Polymerase Chain Reaction; Species Specificity; Teicoplanin; Tigecycline; Time Factors; Vancomycin | 2013 |
Effects of linezolid on suppressing in vivo production of staphylococcal toxins and improving survival outcomes in a rabbit model of methicillin-resistant Staphylococcus aureus necrotizing pneumonia.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bacterial Load; Bacterial Toxins; Chemokine CCL2; Disease Models, Animal; Exotoxins; Hemolysin Proteins; Interleukin-8; Leukocidins; Linezolid; Lung; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Rabbits; Vancomycin | 2013 |
Host gene expression profiling and in vivo cytokine studies to characterize the role of linezolid and vancomycin in methicillin-resistant Staphylococcus aureus (MRSA) murine sepsis model.
Topics: Acetamides; Animals; Gene Expression Profiling; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Oxazolidinones; Sepsis; Vancomycin | 2013 |
Antimicrobial/anti-biofilm activity of expired blood platelets and their released products.
Topics: Acetamides; Anti-Bacterial Agents; Anti-Infective Agents; beta-Thromboglobulin; Biofilms; Blood Platelets; Endocarditis, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Oxacillin; Oxazolidinones; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Vancomycin | 2013 |
Antimicrobial activity of ceftaroline tested against staphylococci with reduced susceptibility to linezolid, daptomycin, or vancomycin from U.S. hospitals, 2008 to 2011.
Topics: Acetamides; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Daptomycin; Hospitals; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2013 |
Linezolid versus vancomycin for the treatment of methicillin-resistant Staphylococcus aureus keratitis in rabbits.
Topics: Acetamides; Administration, Topical; Animals; Anti-Bacterial Agents; Bacterial Load; Colony Count, Microbial; Colony-Forming Units Assay; Corneal Ulcer; Disease Models, Animal; Eye Infections, Bacterial; Linezolid; Methicillin-Resistant Staphylococcus aureus; Ophthalmic Solutions; Oxazolidinones; Rabbits; Staphylococcal Infections; Vancomycin | 2013 |
Vancomycin versus linezolid in the treatment of methicillin-resistant Staphylococcus aureus meningitis.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Cohort Studies; Female; Humans; Linezolid; Male; Meningitis, Bacterial; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Oxazolidinones; Retrospective Studies; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2013 |
Influence of the MBC/MIC ratio on the antibacterial activity of vancomycin versus linezolid against methicillin-resistant Staphylococcus aureus isolates in a pharmacodynamic model simulating serum and soft tissue interstitial fluid concentrations reported
Topics: Acetamides; Anti-Bacterial Agents; Diabetes Mellitus; Extracellular Fluid; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microbial Viability; Models, Theoretical; Oxazolidinones; Serum; Vancomycin | 2013 |
Virulence of vancomycin-resistant Enterococcus faecium according to linezolid resistance and clinical outbreak status.
Topics: Acetamides; Animals; Chicago; Disease Models, Animal; Disease Outbreaks; Disk Diffusion Antimicrobial Tests; Enterococcus faecium; Gram-Positive Bacterial Infections; Hospital Bed Capacity, 500 and over; Humans; Kaplan-Meier Estimate; Linezolid; Moths; Oxazolidinones; Time Factors; Vancomycin; Vancomycin Resistance | 2013 |
Analysis of the small RNA transcriptional response in multidrug-resistant Staphylococcus aureus after antimicrobial exposure.
Topics: Acetamides; Anti-Bacterial Agents; Cephalosporins; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Protein Biosynthesis; RNA, Bacterial; RNA, Messenger; RNA, Small Untranslated; Sequence Analysis, RNA; Tigecycline; Transcription, Genetic; Vancomycin | 2013 |
Efficacy of topical and systemic antibiotic treatment of meticillin-resistant Staphylococcus aureus in a murine superficial skin wound infection model.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bacterial Load; Bridged Bicyclo Compounds, Heterocyclic; Diterpenes; Female; Fusidic Acid; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Mupirocin; Oxazolidinones; Staphylococcal Skin Infections; Vancomycin; Wound Infection | 2013 |
[The incidence and risk factors for heterogeneous vancomycin intermediate Staphylococcus aureus].
Topics: Acetamides; Aged; Anti-Bacterial Agents; Area Under Curve; Case-Control Studies; Humans; Incidence; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Prevalence; Pulmonary Disease, Chronic Obstructive; Retrospective Studies; Risk Factors; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Treatment Outcome; Vancomycin; Vancomycin Resistance | 2013 |
Molecular characterization and antibiotic resistance of clinical isolates of methicillin-resistant Staphylococcus aureus obtained from Southeast of Iran (Kerman).
Topics: Acetamides; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Bacterial Typing Techniques; Child; Child, Preschool; Ciprofloxacin; Clindamycin; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Erythromycin; Exotoxins; Gentamicins; Humans; Infant; Iran; Leukocidins; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Micrococcal Nuclease; Middle Aged; Oxazolidinones; Penicillin-Binding Proteins; Phenotype; Prevalence; Staphylococcal Infections; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin; Young Adult | 2014 |
Comparative evaluation of serotonin toxicity among veterans affairs patients receiving linezolid and vancomycin.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Anticonvulsants; Antidepressive Agents; Antiemetics; Bacterial Infections; Cohort Studies; Drug Interactions; Female; Histamine Antagonists; Humans; Linezolid; Male; Middle Aged; New York; Oxazolidinones; Serotonin; Vancomycin; Veterans; Veterans Health | 2013 |
Activity of linezolid and daptomycin against methicillin-resistant coagulase-negative staphylococci with increased MIC for vancomycin isolated from blood cultures in pediatric patients.
Topics: Acetamides; Anti-Bacterial Agents; Child; Coagulase; Daptomycin; Dose-Response Relationship, Drug; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus; Structure-Activity Relationship; Vancomycin | 2014 |
Activities of fosfomycin and rifampin on planktonic and adherent Enterococcus faecalis strains in an experimental foreign-body infection model.
Topics: Acetamides; Ampicillin; Animals; Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Calorimetry; Daptomycin; Disease Models, Animal; Drug Therapy, Combination; Enterococcus faecalis; Foreign Bodies; Fosfomycin; Gentamicins; Gram-Positive Bacterial Infections; Guinea Pigs; Linezolid; Male; Microbial Sensitivity Tests; Oxazolidinones; Rifampin; Vancomycin | 2014 |
[Retrospective analysis of the Gram-positive bacteria-infected cases in the Department of Hematology].
Topics: Acetamides; Adult; Aged; Female; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Retrospective Studies; Teicoplanin; Vancomycin | 2013 |
Ineffectiveness of daptomycin in the treatment of septic pulmonary emboli and persistent bacteremia caused by methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Bacteremia; Daptomycin; Fatal Outcome; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pulmonary Embolism; Staphylococcal Infections; Treatment Failure; Vancomycin | 2013 |
In vitro and in vivo antibacterial evaluation of cadazolid, a new antibiotic for treatment of Clostridium difficile infections.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Clostridioides difficile; Clostridium Infections; Cricetinae; Enterocolitis, Pseudomembranous; Enterotoxins; Female; Fluoroquinolones; Humans; Linezolid; Male; Metronidazole; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Oxazolidinones; Spores, Bacterial; Survival Analysis; Vancomycin | 2014 |
Investigations of the mode of action and resistance development of cadazolid, a new antibiotic for treatment of Clostridium difficile infections.
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Clostridioides difficile; DNA Gyrase; Drug Resistance, Bacterial; Fidaxomicin; Fluoroquinolones; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Protein Biosynthesis; Recombinant Proteins; RNA; Subcellular Fractions; Transcription, Genetic; Vancomycin | 2014 |
Assessment of an anti-alpha-toxin monoclonal antibody for prevention and treatment of Staphylococcus aureus-induced pneumonia.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Bacterial Toxins; Bronchoalveolar Lavage Fluid; Chemokines; Drug Synergism; Drug Therapy, Combination; Female; Hemolysin Proteins; Immunization, Passive; Kidney; Linezolid; Lung; Mice; Mice, Inbred C57BL; Oxazolidinones; Pneumonia, Staphylococcal; Staphylococcus aureus; Survival Analysis; Vancomycin | 2014 |
Monte Carlo simulation analysis of ceftobiprole, dalbavancin, daptomycin, tigecycline, linezolid and vancomycin pharmacodynamics against intensive care unit-isolated methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Cephalosporins; Computer Simulation; Cross Infection; Daptomycin; Dose-Response Relationship, Drug; Humans; Intensive Care Units; Linezolid; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Minocycline; Models, Biological; Monte Carlo Method; Oxazolidinones; Staphylococcal Infections; Teicoplanin; Tigecycline; Vancomycin | 2014 |
Upregulation of icaA, atlE and aap genes by linezolid but not vancomycin in Staphylococcus epidermidis RP62A biofilms.
Topics: Acetamides; Anti-Bacterial Agents; Biofilms; Gene Expression Profiling; Genes, Bacterial; Linezolid; Oxazolidinones; Real-Time Polymerase Chain Reaction; Staphylococcus epidermidis; Transcriptional Activation; Up-Regulation; Vancomycin | 2014 |
Comparative cost-effectiveness of alternative empiric antimicrobial treatment options for suspected enterococcal bacteremia.
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Cost-Benefit Analysis; Daptomycin; Decision Support Techniques; Drug Resistance, Bacterial; Enterococcus; Humans; Linezolid; Models, Economic; Monte Carlo Method; Oxazolidinones; Quality-Adjusted Life Years; Vancomycin | 2014 |
Activity of ceftobiprole against methicillin-resistant Staphylococcus aureus strains with reduced susceptibility to daptomycin, linezolid or vancomycin, and strains with defined SCCmec types.
Topics: Acetamides; Anti-Bacterial Agents; Cephalosporins; Daptomycin; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Vancomycin | 2014 |
Pharmacological properties of NAI-603, a well-tolerated semisynthetic derivative of ramoplanin.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Depsipeptides; Enterococcus; Female; Linezolid; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred ICR; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Teicoplanin; Vancomycin | 2014 |
Comparative effectiveness of linezolid and vancomycin among a national veterans affairs cohort with methicillin-resistant Staphylococcus aureus pneumonia.
Topics: Acetamides; Administration, Oral; Aged; Anti-Bacterial Agents; Databases, Factual; Electronic Health Records; Female; Humans; Injections, Intravenous; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Bacterial; Propensity Score; Proportional Hazards Models; Retrospective Studies; Treatment Outcome; Vancomycin; Veterans | 2014 |
Genotypically different clones of Staphylococcus aureus are diverse in the antimicrobial susceptibility patterns and biofilm formations.
Topics: Acetamides; Anti-Infective Agents; Biofilms; Daptomycin; Genetic Variation; Genotype; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Viability; Minocycline; Oxazolidinones; Staphylococcal Infections; Tigecycline; Vancomycin | 2013 |
Impact of vancomycin or linezolid therapy on development of renal dysfunction and thrombocytopenia in Japanese patients.
Topics: Acetamides; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Asian People; Drug Monitoring; Female; Humans; Linezolid; Male; Middle Aged; Oxazolidinones; Platelet Count; Renal Insufficiency; Retrospective Studies; Thrombocytopenia; Time Factors; Vancomycin; Young Adult | 2013 |
Antimicrobial synergism against different lineages of methicillin-resistant Staphylococcus aureus carrying SCCmec IV.
Topics: Acetamides; Anti-Bacterial Agents; Biofilms; Biomass; Drug Synergism; Gentamicins; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microbial Viability; Oxazolidinones; Rifampin; Vancomycin | 2014 |
Which antibiotic for hospital acquired pneumonia caused by MRSA?
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Cross Infection; Daptomycin; Humans; Linezolid; Lipoglycopeptides; Methicillin-Resistant Staphylococcus aureus; Minocycline; Oxazolidinones; Pneumonia, Staphylococcal; Tigecycline; Vancomycin; Virginiamycin | 2014 |
[Vancomycin resistant Staphylococcus epidermidis caused prosthesis infection. Linezolid and rifampicin healed the complicated infection].
Topics: Acetamides; Anti-Bacterial Agents; Humans; Knee Prosthesis; Linezolid; Male; Middle Aged; Oxazolidinones; Prosthesis-Related Infections; Rifampin; Staphylococcal Infections; Staphylococcus epidermidis; Treatment Outcome; Vancomycin; Vancomycin Resistance | 2014 |
Linezolid resistance in vancomycin-resistant Enterococcus faecalis and Enterococcus faecium isolates in a Brazilian hospital.
Topics: Acetamides; Brazil; Enterococcus faecalis; Enterococcus faecium; Hospitals; Linezolid; Oxazolidinones; Vancomycin; Vancomycin-Resistant Enterococci | 2014 |
Linezolid dampens neutrophil-mediated inflammation in methicillin-resistant Staphylococcus aureus-induced pneumonia and protects the lung of associated damages.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Antigens, Ly; Bacterial Load; Cytokines; Disease Models, Animal; Endothelial Cells; Immunologic Factors; Injections, Subcutaneous; Linezolid; Lung; Methicillin-Resistant Staphylococcus aureus; Mice; Neutrophils; Oxazolidinones; Peroxidase; Pneumonia, Staphylococcal; Vancomycin | 2014 |
Molecular epidemiology of methicillin-resistant S. aureus in the ICU setting.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Genotyping Techniques; Humans; Intensive Care Units; Italy; Linezolid; Methicillin-Resistant Staphylococcus aureus; Molecular Epidemiology; Oxazolidinones; Staphylococcal Infections; Vancomycin | 2014 |
Predictors of clinical success among a national Veterans Affairs cohort with methicillin-resistant Staphylococcus aureus pneumonia.
Topics: Aged; Anti-Bacterial Agents; Case-Control Studies; Female; Hospitalization; Humans; Intensive Care Units; Linezolid; Logistic Models; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Odds Ratio; Pneumonia, Staphylococcal; Treatment Outcome; United States; Vancomycin; Veterans | 2014 |
Ceftaroline-heteroresistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Daptomycin; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Vancomycin Resistance | 2014 |
Comparison of commercial antimicrobial susceptibility test methods for testing of Staphylococcus aureus and Enterococci against vancomycin, daptomycin, and linezolid.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Enterococcus; Humans; Linezolid; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus; Vancomycin | 2014 |
Comparison of M.I.C.E. and Etest with CLSI agar dilution for antimicrobial susceptibility testing against oxacillin-resistant Staphylococcus spp.
Topics: Acetamides; Agar; Anti-Infective Agents; Drug Resistance, Bacterial; Humans; Linezolid; Microbial Sensitivity Tests; Oxacillin; Oxazolidinones; Regression Analysis; Reproducibility of Results; Staphylococcus; Teicoplanin; Vancomycin | 2014 |
[Pattern dynamics of bacteriemia and sepsis pathogens in ICU patients of emergency service].
Topics: Acetamides; Acinetobacter; Anti-Bacterial Agents; Bacteremia; beta-Lactamases; Candida; Candidiasis; Carbapenems; Cefoperazone; Drug Resistance, Multiple, Bacterial; Enterococcus; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Humans; Intensive Care Units; Klebsiella pneumoniae; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Sepsis; Sulbactam; Vancomycin | 2013 |
In vitro activity of telavancin compared with vancomycin and linezolid against Gram-positive organisms isolated from cancer patients.
Topics: Acetamides; Aminoglycosides; Anti-Bacterial Agents; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Lipoglycopeptides; Microbial Sensitivity Tests; Neoplasms; Oxazolidinones; Vancomycin | 2014 |
In vitro activities of oritavancin and comparators against meticillin-resistant Staphylococcus aureus (MRSA) isolates harbouring the novel mecC gene.
Topics: Acetamides; Anti-Bacterial Agents; Bacterial Proteins; Daptomycin; Gene Expression; Glycopeptides; Linezolid; Lipoglycopeptides; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microbial Viability; Oxazolidinones; Vancomycin | 2014 |
Higher clinical success in patients with ventilator-associated pneumonia due to methicillin-resistant Staphylococcus aureus treated with linezolid compared with vancomycin: results from the IMPACT-HAP study.
Topics: Acetamides; Adult; Anemia; Anti-Bacterial Agents; APACHE; Female; Humans; Kidney Diseases; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Ventilator-Associated; Retrospective Studies; Thrombocytopenia; Treatment Outcome; Vancomycin | 2014 |
Antibiotic treatment patterns across Europe in patients with complicated skin and soft-tissue infections due to meticillin-resistant Staphylococcus aureus: a plea for implementation of early switch and early discharge criteria.
Topics: Acetamides; Administration, Oral; Adult; Aged; Anti-Bacterial Agents; Drug Administration Schedule; Europe; Female; Hospitalization; Humans; Injections, Intravenous; Length of Stay; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Patient Discharge; Practice Guidelines as Topic; Retrospective Studies; Soft Tissue Infections; Staphylococcal Skin Infections; Vancomycin | 2014 |
Experimental study of the efficacy of linezolid alone and in combinations against experimental meningitis due to Staphylococcus aureus strains with decreased susceptibility to beta-lactams and glycopeptides.
Topics: Acetamides; Animals; Anti-Bacterial Agents; beta-Lactam Resistance; beta-Lactams; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Female; Glycopeptides; Linezolid; Meningitis, Bacterial; Microbial Sensitivity Tests; Oxazolidinones; Rabbits; Random Allocation; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2014 |
The effect of inoculum size on selection of in vitro resistance to vancomycin, daptomycin, and linezolid in methicillin-resistant Staphylococcus aureus.
Topics: Acetamides; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Multiple, Bacterial; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Vancomycin | 2014 |
Modeling economic implications of alternative treatment strategies for acute bacterial skin and skin structure infections.
Topics: Acetamides; Acute Disease; Administration, Intravenous; Anti-Bacterial Agents; Daptomycin; Health Expenditures; Humans; Linezolid; Oxazolidinones; Patient Discharge; Skin Diseases, Bacterial; Soft Tissue Infections; United States; Vancomycin | 2014 |
Linezolid and vancomycin-resistant Enterococcus faecium peritonitis in a child after liver transplantation.
Topics: Biliary Atresia; Child, Preschool; Coinfection; Cross Infection; Drug Resistance, Multiple, Bacterial; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Liver Transplantation; Male; Peritonitis; Portoenterostomy, Hepatic; Postoperative Complications; Pseudomonas Infections; RNA, Bacterial; RNA, Ribosomal, 23S; Vancomycin | 2015 |
Binding properties of antimicrobial agents to lipid membranes using surface plasmon resonance.
Topics: Acetamides; Anti-Infective Agents; Cell Membrane; Erythromycin; Linezolid; Membrane Lipids; Oxazolidinones; Surface Plasmon Resonance; Teicoplanin; Vancomycin | 2014 |
Optimization of nebulized delivery of linezolid, daptomycin, and vancomycin aerosol.
Topics: Acetamides; Aerosols; Anti-Bacterial Agents; Daptomycin; Equipment Design; Linezolid; Nebulizers and Vaporizers; Oxazolidinones; Particle Size; Vancomycin | 2014 |
Colistin and anti-Gram-positive bacterial agents against Acinetobacter baumannii.
Topics: Acetamides; Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Colistin; Linezolid; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Oxazolidinones; Time Factors; Vancomycin | 2014 |
Evaluation of the treatment of methicillin-resistant Staphylococcus aureus bacteremia.
Topics: Acetamides; Adult; Aged; Anti-Bacterial Agents; Bacteremia; Daptomycin; Female; Health Care Costs; Hospitalization; Humans; Intensive Care Units; Length of Stay; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Oxazolidinones; Retrospective Studies; Staphylococcal Infections; Tennessee; Treatment Outcome; Vancomycin | 2015 |
Recurrent linezolid-resistant Enterococcus faecalis infection in a patient with pneumonia.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterococcus faecalis; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Middle Aged; Pneumonia, Bacterial; Recurrence; Vancomycin; Vancomycin Resistance | 2015 |
A 5-year survey of antimicrobial susceptibility profiles of methicillin-resistant Staphylococcus aureus (MRSA) isolated from patients with bloodstream infections in Northeast Italy.
Topics: Acetamides; Anti-Bacterial Agents; Blood; Daptomycin; Health Surveys; Humans; Italy; Linezolid; Longitudinal Studies; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Oxazolidinones; Staphylococcal Infections; Teicoplanin; Tigecycline; Vancomycin | 2015 |
Assessing outcomes of adult oncology patients treated with linezolid versus daptomycin for bacteremia due to vancomycin-resistant Enterococcus.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Cohort Studies; Daptomycin; Enterococcus; Female; Humans; Linezolid; Male; Middle Aged; Neoplasms; Retrospective Studies; Treatment Outcome; Vancomycin; Vancomycin Resistance | 2016 |
Anti-alpha-toxin monoclonal antibody and antibiotic combination therapy improves disease outcome and accelerates healing in a Staphylococcus aureus dermonecrosis model.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neutralizing; Bacterial Toxins; Broadly Neutralizing Antibodies; Disease Models, Animal; Drug Therapy, Combination; Female; Hemolysin Proteins; Linezolid; Mice, Inbred BALB C; Necrosis; Staphylococcal Skin Infections; Staphylococcus aureus; Vancomycin | 2015 |
In vitro susceptibility to methicillin, vancomycin and linezolid of staphylococci isolated from bloodstream infections in eastern Turkey.
Topics: Acetamides; Anti-Bacterial Agents; Drug Resistance, Bacterial; Humans; Linezolid; Methicillin; Microbial Sensitivity Tests; Oxazolidinones; Sepsis; Staphylococcal Infections; Staphylococcus aureus; Turkey; Vancomycin | 2014 |
Utilization of antibiotics for methicillin-resistant Staphylococcus aureus infection in cystic fibrosis.
Topics: Adult; Anti-Bacterial Agents; Child; Cross-Sectional Studies; Cystic Fibrosis; Drug Administration Schedule; Drug Therapy, Combination; Health Care Surveys; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Practice Patterns, Physicians'; Rifampin; Staphylococcal Infections; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2015 |
Pharmacodynamic and response surface analysis of linezolid or vancomycin combined with meropenem against Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Interactions; Linezolid; Meropenem; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Thienamycins; Vancomycin | 2015 |
Impact of Clostridium difficile recurrence on hospital readmissions.
Topics: Aminoglycosides; Anti-Bacterial Agents; Carbapenems; Cephalosporins; Clostridioides difficile; Clostridium Infections; Fluoroquinolones; Humans; Intensive Care Units; Linezolid; Multivariate Analysis; Patient Readmission; Recurrence; Regression Analysis; Retrospective Studies; Vancomycin | 2015 |
Clinical and microbiological characteristics of six Staphylococcus pettenkoferi isolates from blood samples.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; DNA, Bacterial; Drug Resistance, Bacterial; Female; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Oxacillin; Phenotype; RNA, Ribosomal, 16S; Sequence Analysis, DNA; Staphylococcal Infections; Staphylococcus; Vancomycin | 2015 |
Linezolid, vancomycin and daptomycin modulate cytokine production, Toll-like receptors and phagocytosis in a human in vitro model of sepsis.
Topics: Acetamides; Anti-Bacterial Agents; Cell Line; Cytokines; Daptomycin; Escherichia coli; Gene Expression Profiling; Gram-Positive Bacteria; Humans; Immunologic Factors; Linezolid; Models, Theoretical; Monocytes; Oxazolidinones; Phagocytosis; Sepsis; Toll-Like Receptors; Vancomycin | 2015 |
Minimal inhibitory concentration drift of glycopeptides and linezolid against S. Aureus at a Chinese children's center, 2009-2013.
Topics: Acetamides; Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; China; Drug Resistance, Bacterial; Female; Hospitals, Pediatric; Humans; Infant; Infant, Newborn; Linezolid; Male; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Vancomycin | 2015 |
Efficacy of linezolid, teicoplanin, and vancomycin in prevention of an experimental polytetrafluoroethylene graft infection model caused by methicillin-resistant Staphylococcus aureus.
Topics: Animals; C-Reactive Protein; Disease Models, Animal; Leukocytes; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Polytetrafluoroethylene; Prealbumin; Prosthesis-Related Infections; Rats, Wistar; Teicoplanin; Treatment Outcome; Vancomycin | 2015 |
MRSA infection in patients hospitalized at Sanglah Hospital: a case series.
Topics: Adult; Aged; Anti-Bacterial Agents; Child; Child, Preschool; Cross Infection; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Risk Factors; Staphylococcal Infections; Vancomycin | 2015 |
MEDI4893* Promotes Survival and Extends the Antibiotic Treatment Window in a Staphylococcus aureus Immunocompromised Pneumonia Model.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antibodies, Neutralizing; Broadly Neutralizing Antibodies; Female; Immunocompromised Host; Linezolid; Lung; Mice; Mice, Inbred C57BL; Pneumonia, Staphylococcal; Staphylococcus aureus; Survival Rate; Vancomycin | 2015 |
TXA709, an FtsZ-Targeting Benzamide Prodrug with Improved Pharmacokinetics and Enhanced In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Benzamides; Cells, Cultured; Cytoskeletal Proteins; Daptomycin; Dogs; Half-Life; Humans; Linezolid; Methicillin; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Microbial Sensitivity Tests; Prodrugs; Pyridines; Rats; Staphylococcal Infections; Thiazoles; Vancomycin | 2015 |
Methicillin-resistant Staphylococcus aureus in North-east Croatia.
Topics: Anti-Bacterial Agents; Croatia; Cross Infection; Drug Resistance, Bacterial; Humans; Incidence; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Public Health; Sentinel Surveillance; Staphylococcal Infections; Teicoplanin; Vancomycin | 2015 |
Comparing the ocular surface effects of topical vancomycin and linezolid for treating bacterial keratitis.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Child, Preschool; Eye; Female; Gram-Positive Bacterial Infections; Humans; Keratitis; Linezolid; Male; Middle Aged; Vancomycin | 2016 |
Antimicrobial susceptibility pattern of vancomycin resistant enterococci to newer antimicrobial agents.
Topics: Anti-Infective Agents; Daptomycin; Humans; Linezolid; Minocycline; Tigecycline; Vancomycin; Vancomycin Resistance; Vancomycin-Resistant Enterococci; Virginiamycin | 2015 |
Telavancin demonstrates activity against methicillin-resistant Staphylococcus aureus isolates with reduced susceptibility to vancomycin, daptomycin, and linezolid in broth microdilution MIC and one-compartment pharmacokinetic/pharmacodynamic models.
Topics: Anti-Bacterial Agents; Daptomycin; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcus aureus; Vancomycin | 2015 |
Japanese nationwide surveillance in 2011 of antibacterial susceptibility patterns of clinical isolates from complicated urinary tract infection cases.
Topics: Aged; Aged, 80 and over; Amikacin; Ampicillin; Anti-Bacterial Agents; Ciprofloxacin; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Escherichia coli; Female; Fluoroquinolones; Gram-Negative Bacteria; Humans; Imipenem; Japan; Klebsiella oxytoca; Klebsiella pneumoniae; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Population Surveillance; Proteus mirabilis; Pseudomonas aeruginosa; Serratia marcescens; Urinary Tract Infections; Vancomycin | 2015 |
Comparison of vancomycin and linezolid in patients with peripheral vascular disease and/or diabetes in an observational European study of complicated skin and soft-tissue infections due to methicillin-resistant Staphylococcus aureus.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Diabetes Complications; Europe; Female; Humans; Length of Stay; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Peripheral Vascular Diseases; Retrospective Studies; Soft Tissue Infections; Staphylococcal Skin Infections; Vancomycin | 2015 |
Could ceftaroline be an alternative therapy for linezolid resistant Staphylococcus epidermidis infections in Intensive Care Medicine?
Topics: Anti-Bacterial Agents; Bacteremia; Body Fluids; Catheter-Related Infections; Ceftaroline; Cephalosporins; Critical Care; Cross Infection; Daptomycin; Drug Resistance, Multiple, Bacterial; Exudates and Transudates; Humans; Linezolid; Methicillin; Minocycline; Staphylococcal Infections; Staphylococcus epidermidis; Tigecycline; Vancomycin | 2015 |
Activity of vancomycin, linezolid, and daptomycin against staphylococci and enterococci isolated in 5 Greek hospitals during a 5-year period (2008-2012).
Topics: Anti-Bacterial Agents; Daptomycin; Drug Utilization; Enterococcus; Gram-Positive Bacterial Infections; Greece; Hospitals; Humans; Linezolid; Microbial Sensitivity Tests; Staphylococcus; Vancomycin | 2015 |
Observed Antagonistic Effect of Linezolid on Daptomycin or Vancomycin Activity against Biofilm-Forming Methicillin-Resistant Staphylococcus aureus in an In Vitro Pharmacodynamic Model.
Topics: Anti-Bacterial Agents; Biofilms; Colony Count, Microbial; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Protein Synthesis Inhibitors; Staphylococcal Infections; Vancomycin | 2015 |
Comparative-effectiveness of vancomycin and linezolid as part of guideline-recommended empiric therapy for healthcare-associated pneumonia.
Topics: Anti-Bacterial Agents; Cross Infection; Drug Therapy, Combination; Female; Humans; Linezolid; Male; Pneumonia, Bacterial; Practice Guidelines as Topic; Retrospective Studies; United States; United States Department of Veterans Affairs; Vancomycin | 2015 |
Efficacy of Single and Combined Antibiotic Treatments of Anthrax in Rabbits.
Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anthrax; Anti-Bacterial Agents; Bacillus anthracis; Bacteremia; Ciprofloxacin; Clarithromycin; Disease Models, Animal; Doxycycline; Drug Combinations; Drug Synergism; Humans; Imipenem; Linezolid; Male; Microbial Sensitivity Tests; Rabbits; Respiratory Tract Infections; Rifampin; Spores, Bacterial; Survival Analysis; Vancomycin | 2015 |
Optimum initial loading dose of vancomycin for pneumonia caused by methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Humans; Linezolid; Methicillin; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Staphylococcus aureus; Vancomycin | 2016 |
Evaluation of tedizolid against Staphylococcus aureus and enterococci with reduced susceptibility to vancomycin, daptomycin or linezolid.
Topics: Anti-Bacterial Agents; Daptomycin; Drug Resistance, Bacterial; Enterococcus; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Organophosphates; Oxazoles; Staphylococcus aureus; Vancomycin | 2016 |
In vitro activity of oritavancin and comparator agents against staphylococci, streptococci and enterococci from clinical infections in Europe and North America, 2011-2014.
Topics: Anti-Bacterial Agents; Daptomycin; Drug Resistance, Multiple, Bacterial; Enterococcus; Europe; Glycopeptides; Humans; Linezolid; Lipoglycopeptides; Microbial Sensitivity Tests; North America; Skin Diseases, Bacterial; Staphylococcal Infections; Staphylococcus; Streptococcal Infections; Streptococcus; Vancomycin | 2015 |
Susceptibility of Clostridium difficile Isolates of Varying Antimicrobial Resistance Phenotypes to SMT19969 and 11 Comparators.
Topics: Aminoglycosides; Anti-Bacterial Agents; Benzimidazoles; Ceftriaxone; Clostridioides difficile; Clostridium Infections; Drug Resistance, Multiple, Bacterial; Fidaxomicin; Fluoroquinolones; Humans; Linezolid; Metronidazole; Microbial Sensitivity Tests; Moxifloxacin; Phenotype; Pyridines; Ribotyping; Vancomycin | 2016 |
Antimicrobial susceptibility and molecular characteristics of methicillin-resistant Staphylococcus aureus in a Japanese secondary care facility.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Toxins; Cross Infection; Daptomycin; Dibekacin; Exotoxins; Humans; Japan; Leukocidins; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Multilocus Sequence Typing; Open Reading Frames; Recombinases; Secondary Care Centers; Skin; Soft Tissue Infections; Staphylococcus aureus; Teicoplanin; Vancomycin; Virulence Factors | 2016 |
Susceptibility Profile of Staphylococcus epidermidis and Staphylococcus haemolyticus Isolated from Blood Cultures to Vancomycin and Novel Antimicrobial Drugs over a Period of 12 Years.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Bacterial Typing Techniques; Blood Culture; Brazil; Daptomycin; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Gene Expression; Hospitals, Teaching; Humans; Linezolid; Minocycline; Mutation; Oxacillin; Prevalence; Staphylococcal Infections; Staphylococcus epidermidis; Staphylococcus haemolyticus; Tigecycline; Vancomycin; Virginiamycin | 2016 |
In vitro activity of dalbavancin and five comparator agents against common and uncommon Gram-positive organisms isolated from cancer patients.
Topics: Anti-Bacterial Agents; Daptomycin; Gram-Positive Bacteria; Humans; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Neoplasms; Teicoplanin; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2016 |
[Evaluation of the tissue diffusion capacity of antibiotics in lower limb ischaemia].
Topics: Aged; Anti-Bacterial Agents; Ceftazidime; Chromatography, High Pressure Liquid; Clindamycin; Female; Humans; Ischemia; Levofloxacin; Linezolid; Lower Extremity; Male; Meropenem; Microbial Sensitivity Tests; Prospective Studies; Skin; Thienamycins; Vancomycin | 2016 |
Augmentation of the Inotropic Effects of Dopamine Following Linezolid Administration in an Infant.
Topics: Anti-Bacterial Agents; Dopamine; Drug Interactions; Enterovirus Infections; Humans; Infant; Intensive Care Units, Pediatric; Intubation, Intratracheal; Linezolid; Picornaviridae Infections; Respiration, Artificial; Respiratory Insufficiency; Selective Serotonin Reuptake Inhibitors; Tetralogy of Fallot; Treatment Outcome; Vancomycin | 2016 |
[A comparison of efficacy and safety of linezolid versus vancomycin for the treatment of infections in patients after allogeneic hematopoietic stem cell transplantation].
Topics: Anti-Bacterial Agents; Gram-Positive Bacterial Infections; Hematopoietic Stem Cell Transplantation; Humans; Linezolid; Vancomycin | 2016 |
Dalbavancin Activity When Tested against Streptococcus pneumoniae Isolated in Medical Centers on Six Continents (2011 to 2014).
Topics: Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Penicillins; Streptococcus pneumoniae; Teicoplanin; Vancomycin | 2016 |
Rifampicin-containing combinations are superior to combinations of vancomycin, linezolid and daptomycin against Staphylococcus aureus biofilm infection in vivo and in vitro.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Daptomycin; Disease Models, Animal; Drug Resistance, Bacterial; Drug Synergism; Drug Therapy, Combination; Female; Linezolid; Mice; Microbial Sensitivity Tests; Osteomyelitis; Prostheses and Implants; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin | 2016 |
Nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus treated with linezolid or vancomycin: A secondary economic analysis of resource use from a Spanish perspective.
Topics: Anti-Bacterial Agents; Cross Infection; Double-Blind Method; Health Care Costs; Humans; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Pneumonia, Staphylococcal; Randomized Controlled Trials as Topic; Treatment Outcome; Vancomycin | 2016 |
Identification of subclinical transmission of vancomycin-resistant enterococcus within an intensive care unit in Taiwan.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Proteins; Carbon-Oxygen Ligases; Cross Infection; Enterococcus faecium; Female; Gram-Positive Bacterial Infections; Humans; Infection Control; Intensive Care Units; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Minocycline; Multilocus Sequence Typing; Taiwan; Tigecycline; Vancomycin; Vancomycin Resistance; Vancomycin-Resistant Enterococci | 2016 |
Combining the FtsZ-Targeting Prodrug TXA709 and the Cephalosporin Cefdinir Confers Synergy and Reduces the Frequency of Resistance in Methicillin-Resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cefdinir; Cephalosporins; Cytoskeletal Proteins; Drug Synergism; Linezolid; Methicillin; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Prodrugs; Staphylococcus aureus; Vancomycin; Vancomycin Resistance | 2016 |
Comparison of Linezolid and Vancomycin for Methicillin-Resistant Staphylococcus aureus Pneumonia: Institutional Implications.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Health Care Costs; Hospitalization; Humans; Length of Stay; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Pneumonia, Staphylococcal; Retrospective Studies; Vancomycin | 2016 |
Antibiotic susceptibility and genomic variations in Staphylococcus aureus associated with Skin and Soft Tissue Infection (SSTI) disease groups.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Bacterial Toxins; Catheter-Related Infections; Clindamycin; Community-Acquired Infections; Cross Infection; Erythromycin; Exfoliatins; Exotoxins; Female; Genotype; Humans; Leukocidins; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Soft Tissue Infections; Staphylococcal Infections; Staphylococcal Skin Infections; Staphylococcus aureus; Superantigens; Taiwan; Teicoplanin; Vancomycin; Virulence Factors | 2016 |
Comparative Efficacies of Tedizolid Phosphate, Linezolid, and Vancomycin in a Murine Model of Subcutaneous Catheter-Related Biofilm Infection Due to Methicillin-Susceptible and -Resistant Staphylococcus aureus.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Catheter-Related Infections; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Mice; Organophosphates; Oxazoles; Staphylococcus aureus; Vancomycin | 2016 |
Antibacterial Efficacy of Eravacycline In Vivo against Gram-Positive and Gram-Negative Organisms.
Topics: Anti-Bacterial Agents; Gram-Negative Bacteria; Gram-Positive Bacteria; Linezolid; Meropenem; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Staphylococcus aureus; Tetracyclines; Thienamycins; Tigecycline; Vancomycin | 2016 |
Congenital Cataract, Nasolacrimal Duct Obstruction, and Methicillin-Resistant Staphylococcus aureus Conjunctivitis: When to Operate?
Topics: Administration, Oral; Administration, Topical; Anti-Bacterial Agents; Cataract; Cataract Extraction; Conjunctivitis, Bacterial; Eye Infections, Bacterial; Humans; Infant; Lacrimal Duct Obstruction; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Nasolacrimal Duct; Staphylococcal Infections; Vancomycin | 2016 |
Simultaneous determination and stability studies of linezolid, meropenem and vancomycin in bacterial growth medium by high-performance liquid chromatography.
Topics: Anti-Bacterial Agents; Chromatography, High Pressure Liquid; Culture Media; Drug Stability; Limit of Detection; Linezolid; Meropenem; Thienamycins; Vancomycin | 2016 |
Methicillin-resistant Staphylococcus aureus in Stockholm, Sweden: Molecular epidemiology and antimicrobial susceptibilities to ceftaroline, linezolid, mupirocin and vancomycin in 2014.
Topics: Anti-Bacterial Agents; Bacterial Typing Techniques; Ceftaroline; Cephalosporins; Genotype; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Epidemiology; Mupirocin; Staphylococcal Infections; Sweden; Vancomycin | 2016 |
Effect of Linezolid on Hematologic Recovery in Newly Diagnosed Acute Myeloid Leukemia Patients Following Induction Chemotherapy.
Topics: Academic Medical Centers; Adult; Anti-Bacterial Agents; Cohort Studies; Daptomycin; Female; Humans; Induction Chemotherapy; Leukemia, Myeloid, Acute; Linezolid; Male; Middle Aged; Neutropenia; Neutrophils; Retrospective Studies; Time Factors; Vancomycin | 2016 |
Cost of nosocomial pneumonia: the example of vancomycin versus linezolid-shorter stay or fewer complications?
Topics: Anti-Bacterial Agents; Cost-Benefit Analysis; Cross Infection; Hospitalization; Humans; Length of Stay; Linezolid; Methicillin-Resistant Staphylococcus aureus; Pneumonia, Staphylococcal; Quality of Life; Renal Insufficiency; Vancomycin | 2016 |
A combination of silver nanoparticles and visible blue light enhances the antibacterial efficacy of ineffective antibiotics against methicillin-resistant Staphylococcus aureus (MRSA).
Topics: Amoxicillin; Anti-Bacterial Agents; Azithromycin; Clarithromycin; Combined Modality Therapy; Drug Combinations; Drug Synergism; Light; Linezolid; Metal Nanoparticles; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phototherapy; Silver; Vancomycin | 2016 |
In vitro ceftaroline combinations against meticillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Daptomycin; Drug Therapy, Combination; Humans; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections; Vancomycin | 2016 |
[Clinical efficacy and safety of vancomycin compared with linezolid for the treatment of neonatal gram-positive bacterial sepsis].
Topics: Acetamides; Anti-Bacterial Agents; Bacteremia; Chi-Square Distribution; Female; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Incidence; Infant, Newborn; Linezolid; Male; Middle Aged; Neonatal Sepsis; Oxazolidinones; Platelet Count; Retrospective Studies; Thrombocytopenia; Treatment Outcome; Vancomycin | 2016 |
Methicillin-resistant Staphylococcus aureus in Zimbabwe.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefoxitin; Child; Child, Preschool; Drug Resistance, Bacterial; Female; Humans; Infant; Infant, Newborn; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Prevalence; Staphylococcal Infections; Teicoplanin; Vancomycin; Young Adult; Zimbabwe | 2016 |
Molecular Epidemiology of Staphylococcus aureus among Patients with Skin and Soft Tissue Infections in Two Chinese Hospitals.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Child; Child, Preschool; China; Female; Hospitals; Humans; Infant; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Molecular Epidemiology; Soft Tissue Infections; Staphylococcal Infections; Staphylococcal Skin Infections; Staphylococcus aureus; Teicoplanin; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin; Young Adult | 2016 |
IVIG-mediated protection against necrotizing pneumonia caused by MRSA.
Topics: Acute Lung Injury; Animals; Antibiotic Prophylaxis; Antibodies, Neutralizing; Bacterial Toxins; Disease Models, Animal; Exotoxins; Hemolysin Proteins; Humans; Immunoglobulins, Intravenous; Leukocidins; Linezolid; Methicillin-Resistant Staphylococcus aureus; Pneumonia, Necrotizing; Rabbits; Vancomycin | 2016 |
Antibiofilm Activity and Synergistic Inhibition of Staphylococcus aureus Biofilms by Bactericidal Protein P128 in Combination with Antibiotics.
Topics: Anti-Bacterial Agents; Biofilms; Ciprofloxacin; Daptomycin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Gentamicins; Linezolid; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Recombinant Fusion Proteins; Staphylococcus aureus; Vancomycin | 2016 |
Vancomycin, teicoplanin, daptomycin, and linezolid MIC creep in methicillin-resistant Staphylococcus aureus is associated with clonality.
Topics: Anti-Bacterial Agents; Daptomycin; Follow-Up Studies; Forecasting; Humans; Incidence; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Retrospective Studies; Staphylococcal Infections; Taiwan; Teicoplanin; Vancomycin | 2016 |
Biofilm Formation on Bandage Contact Lenses Worn by Patients with the Boston Type 1 Keratoprosthesis: A Pilot Comparison Study of Prophylactic Topical Vancomycin 15 mg/mL and Linezolid 0.2.
Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bandages; Biofilms; Contact Lenses, Hydrophilic; Corneal Diseases; Humans; Linezolid; Pilot Projects; Prostheses and Implants; Prosthesis-Related Infections; Vancomycin | 2018 |
Linezolid versus vancomycin for nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus in the elderly: A retrospective cohort analysis: Effectiveness of linezolid in the elderly.
Topics: Aged; Analysis of Variance; Anti-Bacterial Agents; Body Mass Index; Comorbidity; Cross Infection; Female; Hospital Mortality; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Organ Dysfunction Scores; Outcome Assessment, Health Care; Pneumonia, Staphylococcal; Retrospective Studies; Vancomycin | 2017 |
Daptomycin non-susceptible Enterococcus faecium in leukemia patients: Role of prior daptomycin exposure.
Topics: Adult; Anti-Bacterial Agents; Bacteremia; Cohort Studies; Daptomycin; Drug Resistance, Bacterial; Enterococcus faecium; Female; Gram-Positive Bacterial Infections; Humans; Leukemia; Linezolid; Male; Middle Aged; Retrospective Studies; Risk Factors; ROC Curve; Vancomycin | 2017 |
Comparative efficacies of daptomycin, vancomycin, and linezolid in experimental enterococcal peritonitis.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Daptomycin; Disease Models, Animal; Enterococcus; Female; Gram-Positive Bacterial Infections; Linezolid; Mice; Mice, Inbred C57BL; Peritonitis; Vancomycin | 2017 |
Development of advanced biantibiotic loaded bone cement spacers for arthroplasty associated infections.
Topics: Anti-Bacterial Agents; Arthroplasty; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bone Cements; Daptomycin; Drug Combinations; Drug Compounding; Humans; Linezolid; Materials Testing; Microbial Sensitivity Tests; Microspheres; Prosthesis-Related Infections; Staphylococcus aureus; Vancomycin | 2017 |
Effect of Continuous and Sequential Therapy among Veterans Receiving Daptomycin or Linezolid for Vancomycin-Resistant Enterococcus faecium Bacteremia.
Topics: Aged; Anti-Bacterial Agents; Bacteremia; Daptomycin; Enterococcus faecium; Female; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Retrospective Studies; Treatment Outcome; Vancomycin; Vancomycin-Resistant Enterococci; Veterans | 2017 |
Comparative effectiveness of linezolid versus vancomycin as definitive antibiotic therapy for heterogeneously resistant vancomycin-intermediate coagulase-negative staphylococcal central-line-associated bloodstream infections in a neonatal intensive care u
Topics: Anti-Bacterial Agents; Bacteremia; Coagulase; Cohort Studies; Female; Hospital Mortality; Humans; Infant; Infant, Newborn; Intensive Care Units, Neonatal; Linezolid; Male; Retrospective Studies; Staphylococcal Infections; Staphylococcus; Treatment Outcome; Vancomycin | 2017 |
Translational Pharmacometric Evaluation of Typical Antibiotic Broad-Spectrum Combination Therapies Against Staphylococcus Aureus Exploiting In Vitro Information.
Topics: Anti-Bacterial Agents; Computer Simulation; Drug Therapy, Combination; In Vitro Techniques; Linezolid; Meropenem; Microbial Sensitivity Tests; Models, Theoretical; Staphylococcus aureus; Thienamycins; Translational Research, Biomedical; Vancomycin | 2017 |
Linezolid versus vancomycin in Methicillin Resistant Staphylococcus aureus nosocomial pneumonia in the elderly.
Topics: Acetamides; Aged; Anti-Bacterial Agents; Cross Infection; Humans; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Pneumonia, Staphylococcal; Vancomycin | 2017 |
In vitro activities of vancomycin and linezolid against biofilm-producing methicillin-resistant staphylococci species isolated from catheter-related bloodstream infections from an Egyptian tertiary hospital.
Topics: Anti-Bacterial Agents; Bacteremia; Bacterial Proteins; Biofilms; Catheter-Related Infections; Catheters; Drug Resistance, Bacterial; Egypt; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Polymerase Chain Reaction; Rifampin; Staphylococcal Infections; Staphylococcus; Staphylococcus aureus; Tertiary Care Centers; Vancomycin | 2017 |
Enterococci in orthopaedic infections: Who is at risk getting infected?
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cohort Studies; Cross Infection; Daptomycin; Enterococcus; Enterococcus faecium; Female; Gram-Positive Bacterial Infections; Humans; Intraoperative Period; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Orthopedic Procedures; Perioperative Period; Retrospective Studies; Risk Factors; Vancomycin; Young Adult | 2017 |
Colonization prevalence and antibiotic susceptibility of Group B Streptococcus in pregnant women over a 6-year period in Dongguan, China.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Ceftriaxone; China; Erythromycin; Female; Humans; Linezolid; Microbial Sensitivity Tests; Middle Aged; Penicillins; Pregnancy; Prevalence; Streptococcal Infections; Streptococcus agalactiae; Vancomycin; Young Adult | 2017 |
Detection of high levels of resistance to linezolid and vancomycin in Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Carbon-Oxygen Ligases; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections; Vancomycin | 2017 |
Comparative analysis of lactic acidosis induced by linezolid and vancomycin therapy using cohort and case-control studies of incidence and associated risk factors.
Topics: Acid-Base Equilibrium; Acidosis, Lactic; Aged; Aged, 80 and over; Anti-Bacterial Agents; Biomarkers; Chi-Square Distribution; Comorbidity; Female; Humans; Incidence; Lactic Acid; Linezolid; Male; Middle Aged; Odds Ratio; Prognosis; Propensity Score; Renal Insufficiency; Retrospective Studies; Risk Factors; Vancomycin | 2018 |
Characteristics of clinical and environmental vanM-carrying vancomycin-resistant enterococci isolates from an infected patient.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Drug Resistance, Bacterial; Electrophoresis, Gel, Pulsed-Field; Enterococcus faecium; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Vancomycin; Vancomycin-Resistant Enterococci | 2018 |
Genetic Basis of Emerging Vancomycin, Linezolid, and Daptomycin Heteroresistance in a Case of Persistent Enterococcus faecium Bacteremia.
Topics: Aged; Bacteremia; Daptomycin; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combination; Enterococcus faecium; Humans; Linezolid; Male; Microbial Sensitivity Tests; Vancomycin; Vancomycin Resistance | 2018 |
Cellular Pharmacokinetics and Intracellular Activity of Gepotidacin against Staphylococcus aureus Isolates with Different Resistance Phenotypes in Models of Cultured Phagocytic Cells.
Topics: Acenaphthenes; Anti-Bacterial Agents; Azithromycin; Cell Line; Daptomycin; Heterocyclic Compounds, 3-Ring; Humans; Linezolid; Macrolides; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Moxifloxacin; Oxacillin; Phagocytes; Staphylococcus aureus; THP-1 Cells; Vancomycin | 2018 |
Repurposing niclosamide for intestinal decolonization of vancomycin-resistant enterococci.
Topics: Animals; Anti-Bacterial Agents; Depsipeptides; Drug Repositioning; Feces; Humans; Intestines; Linezolid; Mice; Microbial Sensitivity Tests; Niclosamide; Oxyclozanide; Rafoxanide; Salicylanilides; Vancomycin; Vancomycin Resistance; Vancomycin-Resistant Enterococci | 2018 |
ANTI-ADHESIVE AND ANTI-BIOFILM ACTIVITIES IN VITRO OF LINEZOLID, VANCOMYCIN, TIGECYCLINE AND DAPTOMYCIN AGAINST STAPHYLOCOCCUS HAEMOLYTICUS.
Topics: Adhesiveness; Anti-Bacterial Agents; Biofilms; Catheters; Daptomycin; Drug Resistance, Multiple, Bacterial; Linezolid; Microbial Sensitivity Tests; Minocycline; Staphylococcus haemolyticus; Tigecycline; Vancomycin | 2016 |
In vitro activity of tedizolid and comparator agents against clinical Gram-positive isolates recovered from patients with cancer.
Topics: Anti-Bacterial Agents; Daptomycin; Drug Resistance, Bacterial; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Microbial Viability; Oxazolidinones; Tetrazoles; Vancomycin | 2018 |
Molecular analysis of immune evasion cluster (IEC) genes and intercellular adhesion gene cluster (ICA) among methicillin-resistant and methicillin-sensitive isolates of
Topics: Anti-Bacterial Agents; Biofilms; Cell Adhesion Molecules; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Female; Humans; Immune Evasion; Iran; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Multigene Family; Staphylococcal Infections; Staphylococcus aureus; Vancomycin; Virulence Factors | 2017 |
Bacteriological relevance of linezolid vs. vancomycin in postoperative empirical treatment of osteoarticular infections: a retrospective single-center study.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Female; France; Gram-Positive Bacteria; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Osteoarthritis; Piperacillin, Tazobactam Drug Combination; Prosthesis-Related Infections; Retrospective Studies; Surgical Wound Infection; Vancomycin | 2018 |
Daptomycin and vancomycin heteroresistance revealed among CC5-SCCmecII MRSA clone and in vitro evaluation of treatment alternatives.
Topics: Bacterial Proteins; Bacteriolysis; Brazil; Cell Wall; Daptomycin; Drug Resistance, Bacterial; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Multilocus Sequence Typing; Oxazolidinones; Polymorphism, Single Nucleotide; Staphylococcal Infections; Tetrazoles; Vancomycin | 2018 |
Comparative study on safety of linezolid and vancomycin in the treatment of infants and neonates for Gram-positive bacterial infections.
Topics: Anti-Bacterial Agents; Female; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Infant; Infant, Newborn; Linezolid; Male; Vancomycin | 2018 |
Repurposing auranofin as an intestinal decolonizing agent for vancomycin-resistant enterococci.
Topics: Animals; Anti-Bacterial Agents; Auranofin; Biofilms; Drug Repositioning; Drug Resistance, Bacterial; Enterococcus; Female; Intestines; Linezolid; Mice; Mice, Inbred C57BL; Microbial Sensitivity Tests; Vancomycin; Vancomycin Resistance; Vancomycin-Resistant Enterococci | 2018 |
In vitro antibacterial effects of Tanreqing injection combined with vancomycin or linezolid against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Biofilms; Drug Synergism; Drugs, Chinese Herbal; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Vancomycin | 2018 |
The tigecycline evaluation and surveillance trial; assessment of the activity of tigecycline and other selected antibiotics against gram-positive and gram-negative pathogens from France collected between 2004 and 2016.
Topics: Acinetobacter baumannii; Amikacin; Drug Resistance, Multiple, Bacterial; Enterococcus; Escherichia coli; France; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Klebsiella pneumoniae; Levofloxacin; Linezolid; Meropenem; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pseudomonas aeruginosa; Streptococcus pneumoniae; Tigecycline; Vancomycin | 2018 |
Vancomycin or linezolid empiric MRSA coverage with potential ventilator-associated pneumonia has no benefit or effect on outcomes: antibiotic stewardship implications.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antimicrobial Stewardship; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Pneumonia, Ventilator-Associated; Retrospective Studies; Staphylococcal Infections; Treatment Outcome; Vancomycin; Young Adult | 2018 |
Survival of Patients With Vancomycin-Resistant Enterococcus faecium Bacteremia Treated With Conventional or High Doses of Daptomycin or Linezolid Is Associated With the Rate of Bacterial Clearance.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Dose-Response Relationship, Drug; Enterococcus faecium; Female; Humans; Linezolid; Male; Middle Aged; Prospective Studies; Severity of Illness Index; Survival Analysis; Taiwan; Treatment Outcome; Vancomycin; Vancomycin-Resistant Enterococci | 2018 |
A decision support system for antibiotic prescription based on local cumulative antibiograms.
Topics: Algorithms; Anti-Bacterial Agents; Antimicrobial Stewardship; Decision Support Systems, Clinical; Electronic Health Records; Hospitals; Humans; Imipenem; Linezolid; Meropenem; Microbial Sensitivity Tests; Prescriptions; Reproducibility of Results; Software; Vancomycin | 2018 |
Pneumonia Caused by Community-Acquired Methicillin-Resistant
Topics: Adolescent; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Pneumonia; Vancomycin | 2018 |
Assessment of in vivo versus in vitro biofilm formation of clinical methicillin-resistant Staphylococcus aureus isolates from endotracheal tubes.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Genotype; Intubation, Intratracheal; Linezolid; Methicillin-Resistant Staphylococcus aureus; Pneumonia, Ventilator-Associated; Prospective Studies; Random Allocation; Swine; Swine Diseases; Time Factors; Vancomycin | 2018 |
What Is the Best Treatment for Vancomycin-Resistant Enterococcal Bloodstream Infections?
Topics: Anti-Bacterial Agents; Bacteremia; Daptomycin; Enterococcus faecium; Humans; Linezolid; Vancomycin | 2018 |
The impact of earlier intervention by an antimicrobial stewardship team for specific antimicrobials in a single weekly intervention.
Topics: Anti-Infective Agents; Antimicrobial Stewardship; Carbapenems; Daptomycin; Drug Resistance, Microbial; Fluoroquinolones; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Piperacillin, Tazobactam Drug Combination; Pseudomonas aeruginosa; Retrospective Studies; Teicoplanin; Time Factors; Treatment Outcome; Vancomycin | 2018 |
Staphylococcus aureus at an Indian tertiary hospital: Antimicrobial susceptibility and minimum inhibitory concentration (MIC) creep of antimicrobial agents.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Hospitalization; Humans; India; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Rifampin; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Tertiary Care Centers; Vancomycin | 2019 |
Prevalence and antimicrobial susceptibility pattern of Enterococcus species isolated from different clinical samples at Black Lion Specialized Teaching Hospital, Addis Ababa, Ethiopia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Child; Child, Preschool; Doxycycline; Drug Resistance, Bacterial; Enterococcus; Ethiopia; Female; Gram-Positive Bacterial Infections; Hospitals, Teaching; Humans; Infant; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Prevalence; Vancomycin; Young Adult | 2018 |
Comparison of USA300 with non-USA300 methicillin-resistant Staphylococcus aureus in a neonatal intensive care unit.
Topics: Clindamycin; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Female; Hospitalization; Humans; Infant; Infant, Newborn; Intensive Care Units, Neonatal; Japan; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Molecular Typing; Multilocus Sequence Typing; Retrospective Studies; Staphylococcal Infections; Vancomycin; Whole Genome Sequencing | 2019 |
Comparison of molecular epidemiology of bloodstream methicillin-resistant Staphylococcus aureus isolates between a new and an old hospital in central Taiwan.
Topics: Anti-Bacterial Agents; Drug Resistance, Multiple, Bacterial; Erythromycin; Fluoroquinolones; Hospitals; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Molecular Epidemiology; Retrospective Studies; Staphylococcal Infections; Taiwan; Teicoplanin; Vancomycin | 2019 |
Reduction of Inappropriate Antimicrobial Prescriptions in a Tertiary Neonatal Intensive Care Unit After Antimicrobial Stewardship Care Bundle Implementation.
Topics: Anti-Infective Agents; Antimicrobial Stewardship; Drug Utilization; Humans; Inappropriate Prescribing; Infant, Newborn; Intensive Care Units, Neonatal; Linezolid; Meropenem; Patient Care Bundles; Retrospective Studies; Tertiary Care Centers; Vancomycin | 2019 |
Comparative efficacy of human-simulated epithelial lining fluid exposures of tedizolid, linezolid and vancomycin in neutropenic and immunocompetent murine models of staphylococcal pneumonia.
Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Disease Models, Animal; Female; Linezolid; Lung; Mice, Inbred BALB C; Neutropenia; Oxazolidinones; Pneumonia, Staphylococcal; Protein Synthesis Inhibitors; Tetrazoles; Treatment Outcome; Vancomycin | 2019 |
Laboratory Antimicrobial Stewardship During an Outbreak of Linezolid- and Vancomycin-resistant Enterococcus faecium Bacteremia.
Topics: Antimicrobial Stewardship; Bacteremia; Disease Outbreaks; Enterococcus faecium; Humans; Infection Control; Linezolid; Transplant Recipients; Vancomycin; Whole Genome Sequencing | 2019 |
Poultry as a vector for emerging multidrug resistant Enterococcus spp.: First report of vancomycin (van) and the chloramphenicol-florfenicol (cat-fex-cfr) resistance genes from pigeon and duck faeces.
Topics: Animals; Anti-Bacterial Agents; Biofilms; Chloramphenicol; Columbidae; Disease Reservoirs; Disk Diffusion Antimicrobial Tests; Drug Resistance, Multiple, Bacterial; Ducks; Egypt; Enterococcus; Feces; Gene Expression Regulation, Bacterial; Humans; Linezolid; Poultry; Public Health; Thiamphenicol; Vancomycin; Vancomycin-Resistant Enterococci | 2019 |
Utilizing genomic analyses to investigate the first outbreak of vanA vancomycin-resistant Enterococcus in Australia with emergence of daptomycin non-susceptibility.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Australia; Bacteremia; Bacterial Proteins; Carbon-Oxygen Ligases; Cross Infection; Daptomycin; Disease Outbreaks; Enterococcus faecium; Female; Genomics; Genotype; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Multilocus Sequence Typing; Oncology Service, Hospital; Treatment Outcome; Vancomycin; Vancomycin-Resistant Enterococci; Whole Genome Sequencing | 2019 |
Vancomycin-Associated Acute Kidney Injury in a Large Veteran Population.
Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Daptomycin; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Retrospective Studies; Risk Factors; Staphylococcal Infections; United States; United States Department of Veterans Affairs; Vancomycin; Veterans | 2019 |
Analysis of synergy between beta-lactams and anti-methicillin-resistant Staphylococcus aureus agents from the standpoint of strain characteristics and binding action.
Topics: Anti-Bacterial Agents; beta-Lactams; Daptomycin; Drug Synergism; Drug Therapy, Combination; Humans; Linezolid; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections; Vancomycin | 2019 |
Neonatal sepsis due to glycopeptide resistant
Topics: Adult; Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus faecium; Feces; Female; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Linezolid; Male; Microbial Sensitivity Tests; Neonatal Sepsis; Vancomycin; Vancomycin Resistance | 2019 |
Catheter related recurrent blood stream infection caused by linezolid-resistant, methicillin resistant Staphylococcus haemolyticus; an emerging super bug.
Topics: Anti-Bacterial Agents; Baths; Catheter-Related Infections; Chlorhexidine; Cross Infection; Humans; Injections; Linezolid; Male; Methicillin Resistance; Middle Aged; Secondary Prevention; Sepsis; Staphylococcal Infections; Staphylococcus haemolyticus; Vancomycin | 2019 |
In vitro activity of ceftaroline in combination with other antimicrobials active against Staphylococcus spp.
Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Daptomycin; Drug Synergism; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcus; Staphylococcus aureus; Vancomycin | 2020 |
Antibiotic Use and Outcomes After Implementation of the Drug Resistance in Pneumonia Score in ED Patients With Community-Onset Pneumonia.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antimicrobial Stewardship; Community-Acquired Infections; Decision Support Systems, Clinical; Drug Resistance, Bacterial; Emergency Service, Hospital; Escherichia coli Infections; Female; Haemophilus Infections; Health Care Costs; Hospitalization; Humans; Interrupted Time Series Analysis; Length of Stay; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Mortality; Non-Randomized Controlled Trials as Topic; Pneumonia; Pneumonia, Pneumococcal; Pseudomonas Infections; Risk Assessment; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2019 |
Treatment of tricuspid valve endocarditis with daptomycin and linezolid therapy.
Topics: Adult; Anti-Bacterial Agents; Daptomycin; Drug Resistance, Multiple, Bacterial; Drug Substitution; Drug Synergism; Endocarditis, Bacterial; Female; Gentamicins; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections; Treatment Outcome; Tricuspid Valve; Vancomycin | 2019 |
Comparative efficacy of linezolid and vancomycin for endotracheal tube MRSA biofilms from ICU patients.
Topics: Aged; Analysis of Variance; Anti-Bacterial Agents; APACHE; Biofilms; Female; Humans; Intensive Care Units; Intubation, Intratracheal; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microscopy, Electron, Scanning; Middle Aged; Organ Dysfunction Scores; Prospective Studies; Vancomycin | 2019 |
Susceptibility pattern of tracheal tube isolates from Intensive Care Unit of Fauji Foundation Hospital Rawalpindi.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Anti-Bacterial Agents; Biofilms; Cross-Sectional Studies; Drug Resistance, Bacterial; Humans; Intensive Care Units; Intubation, Intratracheal; Klebsiella Infections; Klebsiella pneumoniae; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Pakistan; Pneumonia, Ventilator-Associated; Polymyxin B; Pseudomonas Infections; Staphylococcal Infections; Vancomycin | 2019 |
An integrated microfluidic system for antimicrobial susceptibility testing with antibiotic combination.
Topics: Anti-Bacterial Agents; Gentamicins; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Microfluidic Analytical Techniques; Vancomycin | 2019 |
High sporulation and overexpression of virulence factors in biofilms and reduced susceptibility to vancomycin and linezolid in recurrent Clostridium [Clostridioides] difficile infection isolates.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Biofilms; Clostridioides difficile; Clostridium Infections; Drug Resistance, Bacterial; Humans; Linezolid; Microbiota; Quorum Sensing; Recurrence; Ribotyping; Spores, Bacterial; Vancomycin; Virulence Factors | 2019 |
Linezolid Attenuates Lethal Lung Damage during Postinfluenza Methicillin-Resistant Staphylococcus aureus Pneumonia.
Topics: Animals; Anti-Bacterial Agents; Bacterial Toxins; Female; Gene Expression; Gentamicins; Hemolysin Proteins; L-Lactate Dehydrogenase; Linezolid; Lung; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred C57BL; Orthomyxoviridae Infections; Plasmids; Pneumonia, Staphylococcal; Survival Analysis; Vancomycin | 2019 |
Linezolid versus vancomycin cost in the treatment of staphylococcal pneumonia.
Topics: Aged; Costs and Cost Analysis; Cross Infection; Diagnosis-Related Groups; Drug Costs; Economics, Nursing; Female; France; Hospitalization; Hospitals, Urban; Humans; Infusions, Intravenous; Length of Stay; Linezolid; Male; Middle Aged; Pneumonia, Staphylococcal; Retrospective Studies; Staphylococcus aureus; Vancomycin | 2020 |
Topics: Anti-Bacterial Agents; Daptomycin; Drug Combinations; Drug Resistance, Multiple, Bacterial; Drug Synergism; Humans; Imipenem; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Penicillins; Staphylococcal Infections; Vancomycin | 2020 |
Linezolid vs glycopeptides in the treatment of glycopeptide-susceptible Enterococcus faecium bacteraemia: A propensity score matched comparative study.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Enterococcus faecium; Female; Glycopeptides; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Middle Aged; Propensity Score; Retrospective Studies; Teicoplanin; Treatment Outcome; Vancomycin | 2019 |
Evaluation of the Presence and Characterization of Vancomycin-Intermediate and Heterogeneous Vancomycin-Intermediate Level Resistance Among Bloodstream Isolates of Methicillin-Resistant
Topics: Anti-Bacterial Agents; Bacteremia; Bacterial Typing Techniques; Ceftaroline; Cephalosporins; Drug Resistance, Multiple, Bacterial; Electrophoresis, Gel, Pulsed-Field; Gene Expression; Genes, Bacterial; Humans; Linezolid; Methicillin; Methicillin Resistance; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phylogeny; Rifampin; Staphylococcal Infections; Tetracycline; Turkey; Vancomycin; Vancomycin Resistance; Virginiamycin | 2020 |
Daily practice and prognostic factors for pneumonia caused by methicillin-resistant Staphylococcus aureus in Japan: A multicenter prospective observational cohort study.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Cohort Studies; Cross Infection; Drug Monitoring; Female; Humans; Japan; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Pneumonia, Staphylococcal; Prognosis; Prospective Studies; Risk Factors; Teicoplanin; Treatment Outcome; Vancomycin | 2020 |
Comparative Effectiveness of Vancomycin Versus Linezolid for the Treatment of Acute Pulmonary Exacerbations of Cystic Fibrosis.
Topics: Adult; Anti-Bacterial Agents; Cohort Studies; Cystic Fibrosis; Disease Progression; Female; Hospitalization; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Respiratory Function Tests; Retrospective Studies; Treatment Outcome; Vancomycin | 2020 |
Understanding resistance in enterococcal infections.
Topics: Anti-Bacterial Agents; Bacteremia; Critical Illness; Daptomycin; Drug Resistance, Multiple; Endocarditis; Enterococcus faecium; Humans; Intraabdominal Infections; Linezolid; Microbial Sensitivity Tests; Tigecycline; Vancomycin | 2020 |
Protective activity of anti-lipoteichoic acid monoclonal antibody in single or combination therapies in methicillin-resistant Staphylococcus aureus-induced murine sepsis models.
Topics: Animals; Anti-Bacterial Agents; Antibodies, Bacterial; Antibodies, Monoclonal; Daptomycin; Disease Models, Animal; Drug Therapy, Combination; Humans; Linezolid; Lipopolysaccharides; Methicillin-Resistant Staphylococcus aureus; Mice; Sepsis; Staphylococcal Infections; Staphylococcus aureus; Teichoic Acids; Vancomycin | 2020 |
In vitro synergy with fosfomycin plus doxycyclin against linezolid and vancomycin-resistant Enterococcus faecium.
Topics: Anti-Bacterial Agents; Enterococcus faecium; Fosfomycin; Linezolid; Vancomycin | 2020 |
Species and drug susceptibility profiles of staphylococci isolated from healthy children in Eastern Uganda.
Topics: Anti-Bacterial Agents; Daptomycin; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcus aureus; Teicoplanin; Uganda; Vancomycin | 2020 |
MRSA Septicemia With Septic Arthritis and Prostatic, Intraretinal, Periapical, and Lung Abscesses.
Topics: Abscess; Accidental Falls; Anti-Bacterial Agents; Arthritis, Infectious; Diabetes Mellitus, Type 2; Humans; Linezolid; Lung Abscess; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Periapical Abscess; Prostatitis; Retinal Diseases; Sepsis; Staphylococcal Infections; Vancomycin | 2020 |
Synergistic Effects of Thiosemicarbazides with Clinical Drugs against
Topics: Amoxicillin; Anti-Bacterial Agents; Cell Line; Cell Survival; DNA Gyrase; DNA Topoisomerase IV; Drug Combinations; Drug Synergism; Fibroblasts; Gene Expression; Gentamicins; Humans; Levofloxacin; Linezolid; Microbial Sensitivity Tests; Semicarbazides; Staphylococcus aureus; Structure-Activity Relationship; Vancomycin | 2020 |
Case Report: A Polymicrobial Vision-Threatening Eye Infection Associated with Polysubstance Abuse.
Topics: Administration, Ophthalmic; Adult; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Ceftazidime; Cocaine; Cocaine-Related Disorders; Coinfection; Dopamine Uptake Inhibitors; Doxycycline; Endophthalmitis; Female; Gram-Positive Bacterial Infections; Humans; Keratitis; Kingella; Linezolid; Moxifloxacin; Neisseriaceae Infections; Ophthalmic Solutions; Prednisone; Propionibacterium acnes; Streptococcal Infections; Streptococcus; Substance Abuse, Intravenous; Tobramycin; Vancomycin; Voriconazole | 2020 |
Hospital outbreak of linezolid-resistant and vancomycin-resistant ST80 Enterococcus faecium harbouring an optrA-encoding conjugative plasmid investigated by whole-genome sequencing.
Topics: Anti-Bacterial Agents; Disease Outbreaks; Drug Resistance, Multiple, Bacterial; Enterococcus faecium; Genes, Bacterial; Genotype; Gram-Positive Bacterial Infections; Hospitals; Humans; Ireland; Linezolid; Microbial Sensitivity Tests; Phenotype; Plasmids; RNA, Ribosomal, 23S; Vancomycin; Whole Genome Sequencing | 2020 |
Low prevalence of combined linezolid- and vancomycin-resistant Enterococcus faecium from hospital admission screening in an endemic region in Germany.
Topics: Anti-Bacterial Agents; Enterococcus faecium; Germany; Gram-Positive Bacterial Infections; Hospitals; Humans; Linezolid; Prevalence; Vancomycin; Vancomycin-Resistant Enterococci | 2020 |
Delafloxacin activity against Staphylococcus aureus with reduced susceptibility or resistance to methicillin, vancomycin, daptomycin or linezolid.
Topics: Anti-Bacterial Agents; Daptomycin; Fluoroquinolones; Humans; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2020 |
Positron Emission Tomography/Computed Tomography-Based Diagnosis of Endotipsitis.
Topics: Anti-Bacterial Agents; Ascites; Bacteremia; Biomarkers; Diagnosis, Differential; Drug Therapy, Combination; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Male; Middle Aged; Portasystemic Shunt, Transjugular Intrahepatic; Positron Emission Tomography Computed Tomography; Vancomycin | 2021 |
Comparison of solithromycin with erythromycin in Enterococcus faecalis and Enterococcus faecium from China: antibacterial activity, clonality, resistance mechanism, and inhibition of biofilm formation.
Topics: Anti-Bacterial Agents; Biofilms; China; Cross Infection; Drug Resistance, Bacterial; Enterococcus faecalis; Enterococcus faecium; Erythromycin; Linezolid; Macrolides; Microbial Sensitivity Tests; Triazoles; Vancomycin | 2021 |
Vancomycin-resistant enterococci infection and predisposing factors for infection and mortality in patients with acute leukaemia and febrile neutropenia.
Topics: Adult; Age Factors; Aged; Anti-Bacterial Agents; Bacteremia; Cross Infection; Daptomycin; Enterococcus faecium; Febrile Neutropenia; Female; Gram-Positive Bacterial Infections; Hospital Mortality; Humans; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Linezolid; Male; Middle Aged; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proportional Hazards Models; Retrospective Studies; Risk Factors; Sex Factors; Soft Tissue Infections; Turkey; Urinary Tract Infections; Vancomycin; Vancomycin Resistance | 2020 |
Rates of bacterial co-infections and antimicrobial use in COVID-19 patients: a retrospective cohort study in light of antibiotic stewardship.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Antifungal Agents; Antimicrobial Stewardship; Aspergillosis; Azithromycin; Bacterial Infections; Cohort Studies; Coinfection; COVID-19; Enterobacteriaceae Infections; Escherichia coli Infections; Female; Germany; Humans; Klebsiella Infections; Linezolid; Male; Meropenem; Middle Aged; Piperacillin, Tazobactam Drug Combination; Practice Patterns, Physicians'; Retrospective Studies; SARS-CoV-2; Staphylococcal Infections; Streptococcal Infections; Sulbactam; Vancomycin; Young Adult | 2021 |
Trends of the Use of Anti-methicillin-Resistant Staphylococcus aureus Agents in Japan Based on Sales Data from 2006 to 2015.
Topics: Anti-Bacterial Agents; Commerce; Data Analysis; Humans; Japan; Linezolid; Methicillin-Resistant Staphylococcus aureus; Staphylococcal Infections; Vancomycin | 2020 |
Emergence of linezolid-resistance in vancomycin-resistant Enterococcus faecium ST117 associated with increased linezolid-consumption.
Topics: Anti-Bacterial Agents; Drug Resistance, Bacterial; Enterococcus faecium; Germany; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Retrospective Studies; RNA, Ribosomal, 23S; Vancomycin; Vancomycin Resistance | 2021 |
Emergency department methicillin-resistant Staphylococcus aureus nare screen effect on pneumonia treatment duration.
Topics: Adult; Aged; Anti-Bacterial Agents; Emergency Service, Hospital; Female; Hospitalization; Humans; Linezolid; Male; Mass Screening; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Nasal Cavity; Pneumonia, Staphylococcal; Retrospective Studies; Time Factors; Vancomycin | 2021 |
A case of Corynebacterium striatum endocarditis successfully treated with an early switch to oral antimicrobial therapy.
Topics: Aged; Anti-Bacterial Agents; Anti-Infective Agents; Corynebacterium; Endocarditis; Endocarditis, Bacterial; Female; Humans; Linezolid; Vancomycin | 2021 |
Comparison of linezolid step-down therapy to standard parenteral therapy in methicillin-resistant Staphylococcus aureus bloodstream infections.
Topics: Adult; Aged; Anti-Bacterial Agents; Daptomycin; Drug Administration Routes; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Middle Aged; Retrospective Studies; Sepsis; Staphylococcal Infections; Treatment Outcome; Vancomycin | 2021 |
Different incidences of acute kidney injury (AKI) and outcomes in COVID-19 patients with and without non-azithromycin antibiotics: A retrospective study.
Topics: Acute Kidney Injury; Adult; Angiotensin-Converting Enzyme Inhibitors; Antiviral Agents; Azithromycin; Coinfection; COVID-19; COVID-19 Drug Treatment; Critical Care; Drug Combinations; Female; Hospital Mortality; Hospitalization; Humans; Iran; Linezolid; Lopinavir; Male; Middle Aged; Retrospective Studies; Ribavirin; Ritonavir; SARS-CoV-2; Treatment Outcome; Vancomycin | 2021 |
Antimicrobial susceptibility of bacteremic vancomycin-resistant Enterococcus faecium to eravacycline, omadacycline, lipoglycopeptides, and other comparator antibiotics: Results from the 2019-2020 Nationwide Surveillance of Multicenter Antimicrobial Resist
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteremia; Daptomycin; Drug Resistance, Bacterial; Enterococcus faecium; Epidemiological Monitoring; Gram-Positive Bacterial Infections; Humans; Linezolid; Lipoglycopeptides; Microbial Sensitivity Tests; Oxazolidinones; Taiwan; Tetracyclines; Tetrazoles; Tigecycline; Vancomycin; Vancomycin-Resistant Enterococci; Virginiamycin | 2021 |
Occurrence of multidrug-resistant Enterococcus faecium isolated from environmental samples.
Topics: Aminoglycosides; Anti-Bacterial Agents; Ciprofloxacin; Cross Infection; DNA, Bacterial; Drug Resistance, Multiple, Bacterial; Enterococcus faecium; Environmental Microbiology; Fluoroquinolones; Gram-Positive Bacterial Infections; Linezolid; Microbial Sensitivity Tests; Polymerase Chain Reaction; Prevalence; Vancomycin; Virulence; Virulence Factors | 2021 |
Optimization of dosing regimens of vancomycin, teicoplanin, linezolid and daptomycin against methicillin-resistant
Topics: Adult; Age Factors; Aged; Anti-Bacterial Agents; Body Weight; Chemotherapy-Induced Febrile Neutropenia; Creatinine; Daptomycin; Dose-Response Relationship, Drug; Female; Humans; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Middle Aged; Monte Carlo Method; Staphylococcal Infections; Teicoplanin; Vancomycin | 2021 |
Antimicrobial susceptibility of gram-positive and gram-negative bacteria: a 5-year retrospective analysis at a multi-hospital healthcare system in Saudi Arabia.
Topics: Adult; Anti-Bacterial Agents; Colistin; Cross Infection; Delivery of Health Care; Drug Resistance, Multiple, Bacterial; Female; Gram-Negative Bacteria; Gram-Positive Bacteria; Hospitals; Humans; Linezolid; Male; Microbial Sensitivity Tests; Middle Aged; Retrospective Studies; Saudi Arabia; Sensitivity and Specificity; Tigecycline; Vancomycin | 2021 |
Nationwide surveillance of antimicrobial resistance in invasive isolates of Streptococcus pneumoniae in Taiwan from 2017 to 2019.
Topics: Aged; Anti-Bacterial Agents; Ceftriaxone; Doripenem; Drug Resistance, Bacterial; Ertapenem; Humans; Levofloxacin; Linezolid; Meningitis, Pneumococcal; Microbial Sensitivity Tests; Penicillins; Pneumococcal Infections; Streptococcus pneumoniae; Taiwan; Vancomycin | 2022 |
Effect of ZnO nanoparticles on methicillin, vancomycin, linezolid resistance and biofilm formation in Staphylococcus aureus isolates.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Biofilms; Drug Resistance, Multiple, Bacterial; Humans; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Nanoparticles; Pseudomonas aeruginosa; Reverse Transcriptase Polymerase Chain Reaction; Staphylococcus aureus; Vancomycin; Vancomycin Resistance; Zinc Oxide | 2021 |
Exploratory Cost-Effectiveness Analysis for Treatment of Methicillin-Resistant Staphylococcus aureus Bloodstream Infections: Is Linezolid or Daptomycin Favored Over Vancomycin?
Topics: Acetamides; Anti-Bacterial Agents; Cost-Benefit Analysis; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Sepsis; Staphylococcal Infections; Vancomycin | 2021 |
Vertebral osteomyelitis caused by vancomycin-resistant Enterococcus spp.: a case series.
Topics: Aged; Aged, 80 and over; Ampicillin; Anti-Bacterial Agents; Daptomycin; Discitis; Drug Resistance, Multiple, Bacterial; Enterococcus faecalis; Enterococcus faecium; Female; Gentamicins; Humans; Italy; Linezolid; Male; Middle Aged; Osteomyelitis; Retrospective Studies; Vancomycin; Vancomycin Resistance; Vancomycin-Resistant Enterococci; Young Adult | 2021 |
Occurrence, Phenotypic and Molecular Characteristics of Vancomycin-Resistant Enterococci Isolated from Retail Raw Milk in Egypt.
Topics: Animals; Anti-Bacterial Agents; Cattle; Egypt; Enterococcus faecium; Female; Gram-Positive Bacterial Infections; Linezolid; Microbial Sensitivity Tests; Milk; Multiplex Polymerase Chain Reaction; Teicoplanin; Vancomycin; Vancomycin Resistance; Vancomycin-Resistant Enterococci | 2022 |
Comparison of Methods for Determining the Antibiotic Susceptibility of Aerococcus Species in a Clinical Setting.
Topics: Aerococcus; Agar; Animals; Anti-Bacterial Agents; Humans; Linezolid; Meropenem; Microbial Sensitivity Tests; Sheep; Tetracyclines; Vancomycin | 2022 |
Cost-minimisation analysis of oritavancin for the treatment of acute bacterial skin and skin structure infections from a United Kingdom perspective.
Topics: Anti-Bacterial Agents; Daptomycin; Floxacillin; Glycopeptides; Humans; Linezolid; Lipoglycopeptides; Methicillin-Resistant Staphylococcus aureus; Quality of Life; State Medicine; Teicoplanin; Vancomycin | 2022 |
Trends of Antimicrobial Susceptibility in Clinically Significant Coagulase-Negative Staphylococci Isolated from Cerebrospinal Fluid Cultures in Neurosurgical Adults: a Nine-Year Analysis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Proteins; Cerebral Ventriculitis; Cerebrospinal Fluid; Coagulase; Cross Infection; Drug Resistance, Bacterial; Female; Humans; Linezolid; Male; Meningitis, Bacterial; Microbial Sensitivity Tests; Middle Aged; Staphylococcal Infections; Staphylococcus; Vancomycin; Young Adult | 2022 |
Multi-site infection by methicillin-resistant Staphylococcus aureus in a six-year old girl: a case report.
Topics: Anti-Bacterial Agents; Child; Community-Acquired Infections; Female; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Staphylococcal Infections; Vancomycin | 2022 |
Effects of linezolid on the haematological system in very low birth weight infants: A single-centre retrospective study.
Topics: Adult; Anti-Bacterial Agents; Humans; Infant; Infant, Newborn; Infant, Very Low Birth Weight; Linezolid; Retrospective Studies; Thrombocytopenia; Vancomycin | 2022 |
Risk Factors Associated with Failure of Linezolid Therapy in Vancomycin-Resistant
Topics: Anti-Bacterial Agents; Bacteremia; Cohort Studies; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Mexico; Referral and Consultation; Retrospective Studies; Risk Factors; Vancomycin; Vancomycin-Resistant Enterococci | 2022 |
Role of Extracellular DNA in Dalbavancin Activity against Methicillin-Resistant Staphylococcus aureus (MRSA) Biofilms in Patients with Skin and Soft Tissue Infections.
Topics: Anti-Bacterial Agents; Biofilms; DNA; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Soft Tissue Infections; Staphylococcal Infections; Staphylococcus aureus; Teicoplanin; Vancomycin | 2022 |
Ventriculitis and meningitis: by methicillin-resistant
Topics: Anti-Bacterial Agents; Cerebral Ventriculitis; Humans; Linezolid; Meningitis; Methicillin Resistance; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus epidermidis; Vancomycin | 2022 |
Evaluation of the synergistic effect of ceftaroline against methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Ceftaroline; Cephalosporins; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections; Vancomycin | 2022 |
Activity of Tedizolid and Comparator Agents Against Gram-positive Isolates Causing Skin and Skin Structure Infections in Pediatric Patients in United States Hospitals (2015-2019).
Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Daptomycin; Hospitals; Humans; Infant; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Staphylococcus aureus; Tetrazoles; United States; Vancomycin | 2022 |
The evaluation of antibiotic susceptibility pattern and associated risk factors of UTI in tertiary care hospital of Peshawar.
Topics: Amikacin; Anti-Bacterial Agents; Escherichia coli; Female; Fosfomycin; Humans; Imipenem; Klebsiella pneumoniae; Linezolid; Male; Meropenem; Pseudomonas aeruginosa; Risk Factors; Tertiary Care Centers; Urinary Tract Infections; Vancomycin | 2022 |
Comparing the pharmacokinetics and organ/tissue distribution of anti-methicillin-resistant
Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Daptomycin; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Oxazolidinones; Rats; Sepsis; Tissue Distribution; Vancomycin | 2022 |
Library Screening for Synergistic Combinations of FDA-Approved Drugs and Metabolites with Vancomycin against VanA-Type Vancomycin-Resistant Enterococcus faecium.
Topics: Anti-Bacterial Agents; Enterococcus faecium; Gram-Positive Bacterial Infections; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Mupirocin; Rifabutin; Rifamycins; Vancomycin; Vancomycin-Resistant Enterococci | 2022 |
Antimicrobial susceptibility testing of Staphylococcus aureus isolates from patients at a tertiary hospital in Tehran, Iran, 2018-2019.
Topics: Anti-Bacterial Agents; Clindamycin; Cross-Sectional Studies; Humans; Iran; Linezolid; Methicillin-Resistant Staphylococcus aureus; Retrospective Studies; Staphylococcal Infections; Staphylococcus aureus; Tertiary Care Centers; Trimethoprim, Sulfamethoxazole Drug Combination; Vancomycin | 2022 |
Risk Factors and Pathogen Spectrum in Continuous Ambulatory Peritoneal Dialysis-Associated Peritonitis: A Single Center Retrospective Study.
Topics: Anti-Bacterial Agents; Bacteria; C-Reactive Protein; Drug Resistance, Bacterial; Globulins; Humans; Linezolid; Microbial Sensitivity Tests; Peritoneal Dialysis, Continuous Ambulatory; Peritonitis; Retrospective Studies; Risk Factors; Teicoplanin; Vancomycin | 2022 |
Comparative efficacy of dalbavancin alone and with rifampicin against in vitro biofilms in a pharmacodynamic model with methicillin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Biofilms; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Rifampin; Teicoplanin; Vancomycin | 2022 |
A UPLC-MS/MS method for simultaneous determination of eight special-grade antimicrobials in human plasma and application in TDM.
Topics: Anti-Infective Agents; Chromatography, High Pressure Liquid; Chromatography, Liquid; Critical Illness; Drug Monitoring; Humans; Imipenem; Linezolid; Meropenem; Micafungin; Reproducibility of Results; Tandem Mass Spectrometry; Teicoplanin; Tigecycline; Vancomycin; Voriconazole | 2022 |
Genetic and Chemical Screening Reveals Targets and Compounds to Potentiate Gram-Positive Antibiotics against Gram-Negative Bacteria.
Topics: Anti-Bacterial Agents; Erythromycin; Gram-Negative Bacteria; Linezolid; Lipid A; Novobiocin; Oxazolidinones; Rifampin; Vancomycin | 2022 |
Genotypic characterization of vancomycin-resistant
Topics: Anti-Bacterial Agents; beta-Lactams; Cross-Sectional Studies; Erythromycin; Fluoroquinolones; Genotype; Gentamicins; Humans; Linezolid; Pristinamycin; Teicoplanin; Tigecycline; Urinary Tract Infections; Vancomycin; Vancomycin-Resistant Enterococci | 2022 |
Antibiotic Abuse and Antimicrobial Resistance in Hospital Environment: A Retrospective Observational Comparative Study.
Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Cross Infection; Drug Resistance, Bacterial; Escherichia coli; Hospitals; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Nitrofurantoin; Retrospective Studies; Staphylococcus aureus; Vancomycin | 2022 |
Scurvy.
Topics: Anemia; Anticoagulants; Ascorbic Acid; Ascorbic Acid Deficiency; C-Reactive Protein; Colistin; Contracture; Fatigue; Fibrinogen; Humans; Linezolid; Male; Middle Aged; Prothrombin; Renal Insufficiency; Scurvy; Serum Albumin; Thromboplastin; Vancomycin; Vitamins | 2022 |
Computing antimicrobial use/antimicrobial resistance ratios: A novel way to assess inpatient antimicrobial utilization using current National Healthcare Safety Network metrics.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Benchmarking; Carbapenems; COVID-19 Drug Treatment; Daptomycin; Delivery of Health Care; Drug Resistance, Bacterial; Drug Resistance, Multiple, Bacterial; Humans; Inpatients; Linezolid; Meropenem; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Retrospective Studies; Vancomycin | 2022 |
In vitro activity of fosfomycin alone and in combination against Staphylococcus aureus with reduced susceptibility or resistance to methicillin, vancomycin, daptomycin or linezolid.
Topics: Anti-Bacterial Agents; Cefazolin; Ceftaroline; Daptomycin; Fosfomycin; Humans; Linezolid; Methicillin; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2022 |
Frequency and Antibiotic Susceptibility Pattern of Community-associated Methicillin-resistant Staphylococcus Aureus (CA-MRSA) in Uncomplicated Skin and Soft Tissue Infections.
Topics: Agar; Amikacin; Animals; Anti-Bacterial Agents; Clindamycin; Community-Acquired Infections; Female; Furunculosis; Humans; Impetigo; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Minocycline; Rifampin; Soft Tissue Infections; Staphylococcal Infections; Staphylococcal Skin Infections; Teicoplanin; Vancomycin | 2022 |
[Antimicrobial Stewardship Initiatives and Studies by the Hospital Pharmacist: Study of Linezolid-associated Thrombocytopenia].
Topics: Antimicrobial Stewardship; Hospitals; Humans; Kidney Diseases; Linezolid; Pharmacists; Retrospective Studies; Thrombocytopenia; Vancomycin | 2022 |
Evaluation of resazurin microplate method for rapid detection of vancomycin and linezolid resistance in Enterococcus faecalis and Enterococcus faecium clinical isolates.
Topics: Animals; Anti-Bacterial Agents; Enterococcus faecalis; Enterococcus faecium; Gram-Positive Bacterial Infections; Linezolid; Microbial Sensitivity Tests; Vancomycin | 2023 |
A 12-Year Retrospective Analysis of Blood Culture Isolates in the Intensive Care Unit of a Tertiary Hospital in China.
Topics: Amikacin; Anti-Bacterial Agents; Blood Culture; Drug Resistance, Bacterial; Gram-Negative Bacteria; Gram-Positive Bacteria; Humans; Imipenem; Intensive Care Units; Linezolid; Meropenem; Microbial Sensitivity Tests; Retrospective Studies; Sepsis; Teicoplanin; Tertiary Care Centers; Vancomycin | 2023 |
Risk factors for mortality after linezolid treatment of vancomycin-resistant Enterococcus bloodstream infection.
Topics: Anti-Bacterial Agents; Bacteremia; Daptomycin; Gram-Positive Bacterial Infections; Humans; Linezolid; Microbial Sensitivity Tests; Risk Factors; Vancomycin; Vancomycin-Resistant Enterococci | 2023 |
[Adverse drug reactions to multiple antibiotics].
Topics: Anti-Bacterial Agents; Daptomycin; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Staphylococcal Infections; Vancomycin | 2023 |
Nosocomial meningitis caused by Staphylococcus haemolyticus in a child with neutropenia in the absence of intracranial devices: a case report.
Topics: Adolescent; Anti-Bacterial Agents; Child; Coagulase; Cross Infection; Hospitals; Humans; Linezolid; Male; Meningitis, Bacterial; Neutropenia; Rifampin; Staphylococcal Infections; Staphylococcus; Staphylococcus haemolyticus; Vancomycin | 2023 |
Structural and Antibacterial Characterization of a New Benzamide FtsZ Inhibitor with Superior Bactericidal Activity and In Vivo Efficacy Against Multidrug-Resistant
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Benzamides; Cytoskeletal Proteins; Linezolid; Mammals; Methicillin; Methicillin-Resistant Staphylococcus aureus; Mice; Microbial Sensitivity Tests; Prodrugs; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2023 |
Can platelet-rich fibrin act as a natural carrier for antibiotics delivery? A proof-of-concept study for oral surgical procedures.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Escherichia coli; Gentamicins; Humans; Leukocytes; Linezolid; Oral Surgical Procedures; Platelet-Rich Fibrin; Staphylococcus aureus; Vancomycin | 2023 |
Effects of Antibacterial Agents on Cancerous Cell Proliferation.
Topics: Anti-Bacterial Agents; Cell Proliferation; Daptomycin; Humans; Linezolid; Male; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Vancomycin | 2023 |
Design and synthesis of novel arylurea derivatives of aryloxy(1-phenylpropyl) alicyclic diamines with antimicrobial activity against multidrug-resistant Gram-positive bacteria.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Bacteria; Diamines; Gram-Negative Bacteria; Gram-Positive Bacteria; Horses; Linezolid; Mammals; Microbial Sensitivity Tests; Staphylococcus aureus; Vancomycin | 2023 |
Phenotypic and genotypic characterization of linezolid resistance and the effect of antibiotic combinations on methicillin-resistant Staphylococcus aureus clinical isolates.
Topics: Anti-Bacterial Agents; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Phenotype; Staphylococcal Infections; Vancomycin | 2023 |
Sputum culture and antibiotic resistance in elderly inpatients with exacerbation of chronic obstructive pulmonary disease at a tertiary geriatric hospital in southern Vietnam.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Colistin; Cross-Sectional Studies; Drug Resistance, Bacterial; Female; Gentamicins; Hospitals; Humans; Inpatients; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Pulmonary Disease, Chronic Obstructive; Sputum; Teicoplanin; Tobramycin; Vancomycin; Vietnam | 2023 |
Clinical characteristics and antibiotic resistance profile of invasive MRSA infections in newborn inpatients: a retrospective multicenter study from China.
Topics: Anti-Bacterial Agents; Child; Drug Resistance, Microbial; Humans; Infant; Infant, Newborn; Inpatients; Linezolid; Methicillin-Resistant Staphylococcus aureus; Microbial Sensitivity Tests; Retrospective Studies; Staphylococcal Infections; Vancomycin | 2023 |
Model-informed precision dosing of antimicrobial drugs in pediatrics: experiences from a pilot scale program.
Topics: Anti-Bacterial Agents; Bayes Theorem; Child; Clindamycin; Critical Illness; Fluconazole; Humans; Linezolid; Meropenem; Metronidazole; Neoplasms; Piperacillin; Vancomycin | 2023 |
A real-world cost-effectiveness study of vancomycin versus linezolid for the treatment of late-onset neonatal sepsis in the NICU in China.
Topics: Anti-Bacterial Agents; China; Coagulase; Cost-Effectiveness Analysis; Drug Costs; Female; Humans; Infant; Linezolid; Male; Methicillin-Resistant Staphylococcus aureus; Neonatal Sepsis; Retrospective Studies; Treatment Outcome; Vancomycin | 2023 |
Using Culture Sensitivity Reports to Optimize Antimicrobial Therapy: Findings and Implications of Antimicrobial Stewardship Activity in a Hospital in Pakistan.
Topics: Anti-Bacterial Agents; Antimicrobial Stewardship; Hospitals; Humans; Linezolid; Pakistan; Piperacillin, Tazobactam Drug Combination; Vancomycin | 2023 |
Clinical efficacy of psychiatric nursing-based vancomycin in the treatment of Staphylococcus aureus infectious skin diseases.
Topics: Acetamides; Anti-Bacterial Agents; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Oxazolidinones; Psychiatric Nursing; Retrospective Studies; Skin Diseases, Infectious; Staphylococcal Infections; Staphylococcus aureus; Treatment Outcome; Vancomycin | 2023 |
Surveillance and analysis of bacterial resistance in a comprehensive teaching hospital from 2015 to 2017.
Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Resistance, Bacterial; Escherichia coli; Gram-Negative Bacteria; Hospitals, Teaching; Humans; Linezolid; Meropenem; Microbial Sensitivity Tests; Vancomycin | 2023 |
Comparative Study of Linezolid and Vancomycin Regimens in One-Stage Surgery for Treating Limb Traumatic Osteomyelitis Caused by Methicillin-Resistant
Topics: Anti-Bacterial Agents; Extremities; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Osteomyelitis; Retrospective Studies; Vancomycin | 2023 |
Bleeding Complications in Vancomycin-Induced Thrombocytopenia: A Real-world Postmarketing Pharmacovigilance Analysis.
Topics: Anti-Bacterial Agents; Daptomycin; Humans; Linezolid; Methicillin-Resistant Staphylococcus aureus; Pharmacovigilance; Teicoplanin; Thrombocytopenia; Tigecycline; Vancomycin | 2023 |
The Properties of Linezolid, Rifampicin, and Vancomycin, as Well as the Mechanism of Action of Pentamidine, Determine Their Synergy against Gram-Negative Bacteria.
Topics: Anti-Bacterial Agents; Erythromycin; Escherichia coli; Gram-Negative Bacteria; Linezolid; Pentamidine; Reactive Oxygen Species; Rifampin; Tetracycline; Vancomycin | 2023 |
Comparison of Incidence of Hyponatremia between Linezolid and Vancomycin by Propensity Score Matching Analysis.
Topics: Anti-Bacterial Agents; Humans; Hyponatremia; Incidence; Linezolid; Propensity Score; Retrospective Studies; Vancomycin | 2023 |