vancomycin has been researched along with alanylalanine in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (30.30) | 18.2507 |
| 2000's | 12 (36.36) | 29.6817 |
| 2010's | 9 (27.27) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Billot-Klein, D; Collatz, E; Gutmann, L; van Heijenoort, J | 1 |
| Arthur, M; Courvalin, P; Depardieu, F; Dutka-Malen, S; Reynolds, PE | 1 |
| Fan, C; Knox, JR; Moews, PC; Walsh, CT | 1 |
| Walsh, CT; Wu, Z | 1 |
| Park, IS; Walsh, CT | 1 |
| Isaacs, L; Lahiri, J; Rao, J; Weis, RM; Whitesides, GM | 1 |
| Bussiere, DE; Holzman, T; Katz, L; Park, CH; Pratt, SD; Severin, JM | 1 |
| Chen, Z; Fukuzawa, S; Ge, M; Kahne, D; Kerns, R; Kohler, J; Onishi, HR; Silver, LL; Thompson, C | 1 |
| Walsh, C | 1 |
| Brandt, JJ; Chatwood, LL; Crowder, MW; Yang, KW | 1 |
| Holmlin, RE; Kane, RS; Metallo, SJ; Whitesides, GM | 1 |
| Courvalin, P; Depardieu, F; Msadek, T | 1 |
| Lee, JG; Roland, C; Sagui, C | 1 |
| Gao, P; Gu, H; Xu, B; Yang, Z; Yuan, F; Zhang, Y | 1 |
| Axelsen, PH; Jusuf, S | 1 |
| Barrett, D; Chen, L; Donadio, S; Falcone, B; Kahne, D; Leimkuhler, C; Oberthür, M; Panzone, G; Sun, B; Walker, S | 1 |
| Chen, YC; Lin, YS; Tsai, PJ; Weng, MF | 1 |
| Boger, DL; Crowley, BM | 1 |
| Deghorain, M; Dufrêne, YF; Errington, J; Gilbert, Y; Gruber, HJ; Hallet, B; Haulot, X; Hols, P; Pollheimer, PD; Verbelen, C; Wang, L; Xu, B | 1 |
| Filipe, SR; Pereira, PM; Pinho, MG; Tomasz, A | 1 |
| Kim, SJ; Matsuoka, S; Patti, GJ; Schaefer, J | 1 |
| Chen, J; Gross, ML; Patti, GJ; Schaefer, J | 1 |
| Beaudoin, JA; Cianci, AL; Quinn, RK; Sculimbrene, BR | 1 |
| Boger, DL; James, RC; Okano, A; Pierce, JG; Xie, J | 1 |
| Hesketh, AR; Hill, L; Hong, HJ; Kwun, MJ; Novotna, G | 1 |
| Boger, DL; Pinchman, JR | 1 |
| Boger, DL; Nakayama, A; Okano, A; Schammel, AW | 1 |
| Du, X; Epstein, IR; Haburcak, R; Huang, Y; Shi, J; Wu, D; Xu, B; Yuan, D; Zhang, Y; Zhou, J | 1 |
| Jung, YS; Kim, JM; Lee, S; Park, IS | 1 |
| Chang, JD; Foster, EE; Kim, SJ; Yang, H | 1 |
| Kim, SJ; Schaefer, J; Sharif, S; Singh, M | 1 |
| Bucci, R; Erba, E; Facchetti, G; Fusè, M; Gandolfi, R; Pellegrino, S; Rimoldi, I | 1 |
| Kemmink, J; Liskamp, RMJ; Rijkers, DTS; Yang, X | 1 |
33 other study(ies) available for vancomycin and alanylalanine
| Article | Year |
|---|---|
Analysis of peptidoglycan precursors in vancomycin-resistant enterococci.
Topics: Cells, Cultured; Chromatography, High Pressure Liquid; Dipeptides; Drug Resistance, Microbial; Enterococcus; Peptidoglycan; Uridine Diphosphate N-Acetylmuramic Acid; Vancomycin | 1992 |
Glycopeptide resistance mediated by enterococcal transposon Tn1546 requires production of VanX for hydrolysis of D-alanyl-D-alanine.
Topics: Alanine; Amino Acid Sequence; Bacterial Proteins; Base Sequence; Carbon-Oxygen Ligases; Dipeptides; DNA Transposable Elements; Drug Resistance, Microbial; Enterococcus faecium; Gene Expression Regulation, Bacterial; Genes, Bacterial; Hydrolysis; Lactates; Ligases; Molecular Sequence Data; Peptidoglycan; Protein Kinases; Pyruvates; Pyruvic Acid; Serine-Type D-Ala-D-Ala Carboxypeptidase; Teicoplanin; Transcription Factors; Vancomycin | 1994 |
Vancomycin resistance: structure of D-alanine:D-alanine ligase at 2.3 A resolution.
Topics: Adenosine Diphosphate; Amino Acid Sequence; Bacterial Proteins; Binding Sites; Carbon-Oxygen Ligases; Computer Graphics; Crystallography, X-Ray; Dipeptides; Drug Resistance, Microbial; Escherichia coli; Hydrogen Bonding; Ligases; Models, Molecular; Molecular Sequence Data; Molecular Structure; Peptide Synthases; Protein Structure, Secondary; Protein Structure, Tertiary; Substrate Specificity; Vancomycin | 1994 |
Phosphinate analogs of D-, D-dipeptides: slow-binding inhibition and proteolysis protection of VanX, a D-, D-dipeptidase required for vancomycin resistance in Enterococcus faecium.
Topics: Bacterial Proteins; Binding Sites; Dipeptidases; Dipeptides; Dithionitrobenzoic Acid; Drug Resistance, Microbial; Enterococcus faecium; Kinetics; Organophosphorus Compounds; Propionates; Protease Inhibitors; Recombinant Proteins; Serine-Type D-Ala-D-Ala Carboxypeptidase; Stereoisomerism; Titrimetry; Vancomycin | 1995 |
D-Alanyl-D-lactate and D-alanyl-D-alanine synthesis by D-alanyl-D-alanine ligase from vancomycin-resistant Leuconostoc mesenteroides. Effects of a phenylalanine 261 to tyrosine mutation.
Topics: Alanine; Amino Acid Sequence; Binding Sites; Dipeptides; Drug Resistance, Microbial; Lactates; Leuconostoc; Models, Molecular; Molecular Sequence Data; Peptide Synthases; Phenotype; Phenylalanine; Point Mutation; Sequence Alignment; Tyrosine; Vancomycin | 1997 |
A trivalent system from vancomycin.D-ala-D-Ala with higher affinity than avidin.biotin.
Topics: Alanine; Avidin; Biotin; Calorimetry; Chromatography, High Pressure Liquid; Dipeptides; Kinetics; Ligands; Thermodynamics; Vancomycin | 1998 |
The structure of VanX reveals a novel amino-dipeptidase involved in mediating transposon-based vancomycin resistance.
Topics: Alanine; Amino Acid Sequence; Animals; Bacterial Proteins; Binding Sites; Carboxypeptidases; Copper; Crystallography, X-Ray; Dipeptidases; Dipeptides; DNA Transposable Elements; Drug Resistance, Microbial; Enterococcus faecium; Enzyme Inhibitors; Hedgehog Proteins; Mice; Models, Molecular; Molecular Sequence Data; Organophosphorus Compounds; Propionates; Protein Conformation; Proteins; Sequence Alignment; Sequence Homology, Amino Acid; Serine-Type D-Ala-D-Ala Carboxypeptidase; Structure-Activity Relationship; Trans-Activators; Vancomycin | 1998 |
Vancomycin derivatives that inhibit peptidoglycan biosynthesis without binding D-Ala-D-Ala.
Topics: Anti-Bacterial Agents; Carbohydrates; Cell Membrane; Dipeptides; Drug Design; Drug Resistance, Microbial; Enterococcus faecalis; Escherichia coli; Glycosylation; Hexosyltransferases; Lipid Metabolism; Microbial Sensitivity Tests; Peptidoglycan; Peptidoglycan Glycosyltransferase; Protein Binding; Protein Precursors; Structure-Activity Relationship; Vancomycin | 1999 |
Deconstructing vancomycin.
Topics: Anti-Bacterial Agents; Bacteria; Cell Wall; Dipeptides; Disaccharides; Drug Design; Drug Resistance, Microbial; Escherichia coli; Glycosylation; Hexosyltransferases; Hydrogen Bonding; Peptidoglycan; Peptidoglycan Glycosyltransferase; Structure-Activity Relationship; Vancomycin | 1999 |
Continuous assay for VanX, the D-alanyl-D-alanine dipeptidase required for high-level vancomycin resistance.
Topics: Aniline Compounds; Bacterial Proteins; Dipeptidases; Dipeptides; Drug Resistance, Microbial; Enterococcus faecium; Enzyme Inhibitors; Escherichia coli; Genes, Bacterial; Kinetics; Metals; Recombinant Proteins; Serine-Type D-Ala-D-Ala Carboxypeptidase; Spectrophotometry; Spectrophotometry, Ultraviolet; Substrate Specificity; Vancomycin | 1999 |
Using bifunctional polymers presenting vancomycin and fluorescein groups to direct anti-fluorescein antibodies to self-assembled monolayers presenting d-alanine-d-alanine groups.
Topics: Acrylic Resins; Antibodies; Dipeptides; Fluoresceins; Fluorescent Antibody Technique; Microscopy, Fluorescence; Surface Plasmon Resonance; Surface Properties; Vancomycin | 2003 |
A six amino acid deletion, partially overlapping the VanSB G2 ATP-binding motif, leads to constitutive glycopeptide resistance in VanB-type Enterococcus faecium.
Topics: Bacterial Proteins; Base Sequence; Binding Sites; Dipeptides; Drug Resistance, Bacterial; Enterococcus faecium; Glycopeptides; Histidine Kinase; Ligases; Molecular Sequence Data; Multigene Family; Operon; Peptide Hydrolases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinases; Recombinant Proteins; Sequence Deletion; Teicoplanin; Transcription Factors; Transcription, Genetic; Vancomycin | 2003 |
First principles investigation of vancomycin and teicoplanin binding to bacterial cell wall termini.
Topics: Alanine; Anti-Bacterial Agents; Bacteria; Cell Wall; Dipeptides; Kinetics; Lactates; Teicoplanin; Thermodynamics; Vancomycin | 2004 |
Molecular recognition remolds the self-assembly of hydrogelators and increases the elasticity of the hydrogel by 10(6)-fold.
Topics: Biomimetic Materials; Dipeptides; Elasticity; Hydrogels; Ligands; Models, Molecular; Stereoisomerism; Vancomycin; Viscosity | 2004 |
Synchronized conformational fluctuations and binding site desolvation during molecular recognition.
Topics: Amides; Anti-Bacterial Agents; Binding Sites; Computer Simulation; Dimerization; Dipeptides; Hydrogen Bonding; Ligands; Models, Chemical; Models, Molecular; Protein Binding; Protein Conformation; Software; Solvents; Thermodynamics; Vancomycin; Water | 2004 |
Differential inhibition of Staphylococcus aureus PBP2 by glycopeptide antibiotics.
Topics: Anti-Bacterial Agents; Dipeptides; Kinetics; Microbial Sensitivity Tests; Penicillin-Binding Proteins; Staphylococcus aureus; Substrate Specificity; Uridine Diphosphate N-Acetylmuramic Acid; Vancomycin | 2005 |
Affinity capture using vancomycin-bound magnetic nanoparticles for the MALDI-MS analysis of bacteria.
Topics: Cell Wall; Dipeptides; Gram-Positive Bacteria; Magnetics; Nanoparticles; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Vancomycin | 2005 |
Total synthesis and evaluation of [Psi[CH2NH]Tpg4]vancomycin aglycon: reengineering vancomycin for dual D-Ala-D-Ala and D-Ala-D-Lac binding.
Topics: Alanine; Dipeptides; Kinetics; Lactates; Oligopeptides; Vancomycin | 2006 |
Single-molecule force spectroscopy and imaging of the vancomycin/D-Ala-D-Ala interaction.
Topics: Binding Sites; Cell Wall; Dipeptides; Fluorescent Dyes; Lactococcus lactis; Ligands; Microscopy, Atomic Force; Microscopy, Fluorescence; Nanotechnology; Staphylococcus aureus; Stereoisomerism; Vancomycin | 2007 |
Fluorescence ratio imaging microscopy shows decreased access of vancomycin to cell wall synthetic sites in vancomycin-resistant Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Cell Membrane; Cell Wall; Diffusion; Dipeptides; Kinetics; Microscopy, Fluorescence; Staphylococcus aureus; Vancomycin; Vancomycin Resistance | 2007 |
Vancomycin derivative with damaged D-Ala-D-Ala binding cleft binds to cross-linked peptidoglycan in the cell wall of Staphylococcus aureus.
Topics: Binding Sites; Cell Wall; Cross-Linking Reagents; Dipeptides; Molecular Conformation; Peptidoglycan; Staphylococcus aureus; Vancomycin | 2008 |
Characterization of structural variations in the peptidoglycan of vancomycin-susceptible Enterococcus faecium: understanding glycopeptide-antibiotic binding sites using mass spectrometry.
Topics: Acetylation; Amides; Amines; Binding Sites; Cell Wall; Chromatography, Liquid; Dipeptides; Enterococcus faecium; Glycoside Hydrolases; Hydroxylation; Magnetic Resonance Spectroscopy; Models, Biological; Molecular Structure; Peptides; Peptidoglycan; Succinimides; Tandem Mass Spectrometry; Vancomycin | 2008 |
Synthesis of a D-Ala-D-Ala peptide isostere via olefin cross-metathesis and evaluation of vancomycin binding.
Topics: Alkenes; Anti-Bacterial Agents; Dipeptides; Hydrogen Bonding; Protein Binding; Thermodynamics; Vancomycin | 2010 |
A redesigned vancomycin engineered for dual D-Ala-D-ala And D-Ala-D-Lac binding exhibits potent antimicrobial activity against vancomycin-resistant bacteria.
Topics: Anti-Bacterial Agents; Bacteria; Binding Sites; Cell Wall; Dipeptides; Peptidoglycan; Vancomycin; Vancomycin Resistance | 2011 |
In vivo studies suggest that induction of VanS-dependent vancomycin resistance requires binding of the drug to D-Ala-D-Ala termini in the peptidoglycan cell wall.
Topics: Anti-Bacterial Agents; Bacterial Proteins; Cell Wall; Dipeptides; Gene Expression Regulation, Bacterial; Ligases; Peptidoglycan; Streptomyces coelicolor; Teicoplanin; Transcription, Genetic; Vancomycin; Vancomycin Resistance | 2013 |
Investigation into the functional impact of the vancomycin C-ring aryl chloride.
Topics: Anti-Bacterial Agents; Chlorides; Dipeptides; Humans; Microbial Sensitivity Tests; Staphylococcal Infections; Staphylococcus aureus; Vancomycin | 2013 |
Total synthesis of [Ψ[C(═NH)NH]Tpg(4)]vancomycin and its (4-chlorobiphenyl)methyl derivative: impact of peripheral modifications on vancomycin analogues redesigned for dual D-Ala-D-Ala and D-Ala-D-Lac binding.
Topics: Alanine; Binding Sites; Dipeptides; Lactates; Molecular Conformation; Stereoisomerism; Vancomycin | 2014 |
Ligand-receptor interaction catalyzes the aggregation of small molecules to induce cell necroptosis.
Topics: Apoptosis; Biocatalysis; Cell Adhesion; Cell Survival; Dipeptides; Dose-Response Relationship, Drug; HeLa Cells; Humans; Ligands; Molecular Conformation; Necrosis; Peptides; Protein Aggregates; Structure-Activity Relationship; Surface Properties; Vancomycin; Water | 2015 |
Vancomycin-lnduced fluorescence and morphological changes in bis(dipeptide)-containing biphenyl supramolecules.
Topics: Anti-Bacterial Agents; Dipeptides; Models, Molecular; Molecular Conformation; Spectrometry, Fluorescence; Stereoisomerism; Vancomycin | 2014 |
Quantification of the d-Ala-d-Lac-Terminated Peptidoglycan Structure in Vancomycin-Resistant Enterococcus faecalis Using a Combined Solid-State Nuclear Magnetic Resonance and Mass Spectrometry Analysis.
Topics: Alanine; Anti-Bacterial Agents; Cell Wall; Dipeptides; Endopeptidases; Enterococcus faecalis; Lactates; Magnetic Resonance Spectroscopy; Mass Spectrometry; Peptidoglycan; Uridine Diphosphate N-Acetylmuramic Acid; Vancomycin; Vancomycin Resistance | 2017 |
Desleucyl-Oritavancin with a Damaged d-Ala-d-Ala Binding Site Inhibits the Transpeptidation Step of Cell-Wall Biosynthesis in Whole Cells of Staphylococcus aureus.
Topics: Anti-Bacterial Agents; Binding Sites; Cell Wall; Dipeptides; Fluorine; Glycopeptides; Isotopes; Lipoglycopeptides; Peptidoglycan; Peptidyl Transferases; Staphylococcus aureus; Vancomycin | 2017 |
Alternative Strategy to Obtain Artificial Imine Reductase by Exploiting Vancomycin/D-Ala-D-Ala Interactions with an Iridium Metal Complex.
Topics: Catalysis; Coordination Complexes; Dipeptides; Hydrogenation; Imines; Iridium; Oxidation-Reduction; Vancomycin | 2021 |
Synthesis of a tricyclic hexapeptide -via two consecutive ruthenium-catalyzed macrocyclization steps- with a constrained topology to mimic vancomycin's binding properties toward D-Ala-D-Ala dipeptide.
Topics: Catalysis; Cyclization; Dipeptides; Ruthenium; Vancomycin | 2022 |