vanadates has been researched along with tyrosine in 414 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (6.52) | 18.7374 |
| 1990's | 210 (50.72) | 18.2507 |
| 2000's | 157 (37.92) | 29.6817 |
| 2010's | 20 (4.83) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bixby, JL; Jhabvala, P | 1 |
| Bailey, TL; Burns, C; McVicar, DW; O'Shea, JJ; Smyth, MJ | 1 |
| Chou, MM; Fajardo, JE; Hanafusa, H | 1 |
| Green, SP; Hamilton, JA; Phillips, WA | 1 |
| Heffetz, D; Rutter, WJ; Zick, Y | 1 |
| Barbacid, M; Jing, S; Tapley, P | 1 |
| Dror, R; Geiger, B; Gilon, C; Levitzki, A; Sabanay, I; Volberg, T; Zick, Y | 1 |
| Clarke, PR; Karsenti, E; Leiss, D; Pagano, M | 1 |
| Quelle, DE; Quelle, FW; Wojchowski, DM | 1 |
| Boulet, I; Dunn, AR; Green, SP; Lock, P; Phillips, WA; Ralph, S; Stanley, E | 1 |
| Loeb, J; Vener, AV | 1 |
| Ballotti, R; Filloux, C; Scimeca, JC; Van Obberghen, E | 1 |
| Kume, T; Oishi, M; Watanabe, T | 1 |
| Hadari, YR; LeRoith, D; Nadiv, O; Roberts, CT; Rothenberg, P; Tzahar, E; Yarden, Y; Zick, Y | 1 |
| Calas, B; Chavanieu, A; Grigorescu, F; Vaglio, P | 1 |
| Chiang, TM | 1 |
| Cavadore, JC; Devault, A; Dorée, M; Fesquet, D; Garrigues, AM; Labbé, JC; Lorca, T; Philippe, M; Picard, A | 1 |
| Davidai, G; Hazum, E; Lee, A; Schvartz, I | 1 |
| Burroughs, S; Feinstein, MB; Huang, CK; Lau, LF; Pumiglia, KM | 1 |
| Asplund, T; Heldin, P; Laurent, TC; Thelin, S; Ytterberg, D | 1 |
| Bourgoin, S; Grinstein, S | 1 |
| Hamaguchi, M; Matsuyoshi, N; Nagafuchi, A; Takeichi, M; Taniguchi, S; Tsukita, S | 1 |
| Alberghina, L; Brambilla, R; Morello, L; Peres, A; Sturani, E; Zippel, R | 1 |
| Furuya, W; Grinstein, S; Lu, DJ; Mills, GB | 1 |
| Howard, BD; Zhong, XH | 1 |
| Dutta, A; Hamaguchi, M; Hanafusa, H | 1 |
| Downey, GP; Grinstein, S; Pâquet, MR; Trudel, S | 1 |
| Cruz, TF; Kandel, RA; Mills, G; Pritzker, KP | 1 |
| Geladopoulos, TP; Sotiroudis, TG | 1 |
| Brown, AB; Chan, TM; Chen, YX; Jeng, Y; Tatoyan, A; Yang, DC | 1 |
| Azzi, L; Meijer, L; Wang, JY | 1 |
| Akiyama, T; Oishi, K; Tsukita, S; Yamamoto, T; Yamanashi, Y | 1 |
| Deans, J; Ledbetter, JA; Parsons, M; Schieven, GL; Valentine, M | 1 |
| Grinstein, S; Pâquet, MR; Trudel, S | 1 |
| DiGiovanna, MP; Sartorelli, AC | 1 |
| Rozengurt, E; Sinnett-Smith, J; Zachary, I | 1 |
| Bourassa, C; Chevalier, S; Durocher, Y; Nguyen, LT; Roberts, KD | 1 |
| Bonjour, JP; Caverzasio, J | 1 |
| Cannistra, SA; DiCarlo, J; Druker, B; Griffin, JD; Kanakura, Y | 1 |
| Barnstein, A; Daniel, TO; Kumjian, DA; Rhee, SG | 1 |
| Atherton-Fessler, S; Falk, JL; Lee, MS; Ogg, S; Parker, LL; Piwnica-Worms, H; Swenson, KI | 1 |
| Bushkin, I; Heffetz, D; Roth, J; Zick, Y | 1 |
| Bushkin, I; Dror, R; Heffetz, D; Zick, Y | 1 |
| Cannistra, SA; Druker, B; Furukawa, Y; Griffin, JD; Kanakura, Y; Torimoto, Y | 1 |
| Ciaraldi, TP; Freidenberg, GR; Molina, JM; Olefsky, JM; Thies, RS | 1 |
| Inazu, T; Taniguchi, T; Yamamura, H; Yanagi, S | 1 |
| Kaplan, NO; Knowles, AF; Leis, JF | 1 |
| Klarlund, JK | 1 |
| Courtneidge, SA | 1 |
| Blumenthal, DK; Chan, CP; Gallis, B; Krebs, EG; Pallen, CJ; Wang, JH | 1 |
| Bauer, H; Niemann, H; Simon, E; Snoek, GT; Tamura, T | 1 |
| Gordon, JA; Ryder, JW | 1 |
| Gentleman, S; Martensen, TM; Reid, TW | 1 |
| Bolen, JB; DeSeau, V; Rosen, N | 1 |
| Belin, D; Montesano, R; Orci, L; Pepper, MS; Vassalli, JD | 1 |
| Comoglio, PM; D'Urso, N; Giancotti, FG; Marchisio, PC; Tarone, G | 1 |
| Bernier, M; Laird, DM; Lane, MD | 1 |
| Bordwell, KL; Casnellie, JE; Luhowskyj, S; Mooney, RA | 1 |
| Anderson, DL; Mooney, RA | 1 |
| Burgess, WH; Friesel, R; Maciag, T | 1 |
| Beach, D; Draetta, G; Morla, AO; Wang, JY | 1 |
| Maher, PA | 1 |
| Berruti, G; Martegani, E | 1 |
| Benjamin, TL; Dahl, J; Dawe, CJ; Freund, R; Talmage, DA; Young, AT | 1 |
| Burr, JG; Linder, ME; Van Wart-Hood, JE | 1 |
| Fischer, EH; Glomset, JA; Krebs, EG; Lerea, KM; Tonks, NK | 1 |
| Alberghina, L; Brambilla, R; Comoglio, PM; Morello, L; Sturani, E; Zippel, R | 1 |
| Fehlmann, M; Ferrua, B; Peyron, JF | 1 |
| Boynton, AL; Raptis, L; Whitfield, JF | 1 |
| Branton, P; Meckling-Hansen, K; Nelson, R; Pawson, T | 1 |
| Forchhammer, J; Klarlund, JK; Latini, S | 1 |
| Gresser, MJ; Tracey, AS | 1 |
| Bertrand, O; Boivin, P; Galand, C | 1 |
| Rieber, M; Strasberg Rieber, M | 1 |
| Oliver, JM; Pfeiffer, JR | 1 |
| Auberger, P; Farahi Far, D; Imbert, V; Mari, B; Peyron, JF; Rossi, B | 1 |
| Earp, HS; Huckle, WR | 1 |
| Errasfa, M; Stern, A | 1 |
| Ahmad, F; Deragon, G; Fantus, IG | 1 |
| Goldman, R; Zor, U | 1 |
| Cruz, TF; Grima, DT; Kandel, RA; Pepinsky, B | 1 |
| Modderman, PW; Sonnenberg, A; von dem Borne, AE | 1 |
| Kataoka, H; Makita, M; Nakai, K | 1 |
| Collares-Buzato, CB; Hirst, BH; Jepson, MA; McEwan, GT; Simmons, NL | 1 |
| Buensuceso, C; Mahadevan, L; Montague, F; Rogers, MV | 1 |
| Khandelwal, RL; Pugazhenthi, S | 1 |
| Ikebuchi, H; Nakanishi, M; Sawada, J; Teshima, R | 1 |
| Rieber, M; Rieber, MS | 1 |
| Atfi, A; Boissonneault, M; Chapdelaine, A; Chevalier, S; Drobetsky, E | 1 |
| Ahmad, S; Hollenberg, MD; Laniyonu, A; Saifeddine, M | 1 |
| Doki, Y; Inoue, M; Iwazawa, T; Kadowaki, T; Matsui, S; Oka, H; Shimaya, K; Shiozaki, H; Takeichi, M; Tamura, S | 1 |
| Agostini, E; Aiuti, A; Aiuti, F; Dianzani, F; Giovannetti, A; Oliva, A; Pandolfi, F; Pierdominici, M; Pizzoli, PM | 1 |
| Kim, G; Yurkow, EJ | 1 |
| Avallone, A; D'Alto, V; Fattore, M; Florio, T; Meucci, O; Schettini, G; Scorziello, A | 1 |
| Bjorge, JD; Cheng, HC; Fujita, DJ; O'Connor, TJ; Wang, JH | 1 |
| Bordin, L; Clari, G; Dalla Vecchia, F; Moret, V; Moro, I | 1 |
| Kondo, Y; Kusaka, J; Sato, M; Tsujimoto, H; Yoshida, H; Yura, Y | 1 |
| Feghali, CA; Wright, TM | 1 |
| Mire-Sluis, A; Page, LA; Thorpe, R; Wadhwa, M | 1 |
| Jones, PM; Persaud, SJ; Wheeler-Jones, CP | 1 |
| Furuya, Y; Mashima, K | 1 |
| Meier, T; Perez, GM; Wallace, BG | 1 |
| Hasuma, T; Matsui-Yuasa, I; Min, A; Otani, S; Yano, Y | 1 |
| Broadway, D; Wilden, PA | 1 |
| Chong, AS; Xu, X | 1 |
| Calvo, S; Finbloom, DS; Kraus, MH; Larner, AC; Sweitzer, SM | 1 |
| DuMaine, J; Morrison, AR; Rzymkiewicz, DM | 1 |
| Heruth, DP; Leyva, A; Rothberg, PG; Wetmore, LA | 1 |
| Hamburger, AW; Mishra, S | 1 |
| Bagrodia, S; Shalloway, D; Taylor, SJ | 1 |
| Chao, W; Liu, H; Olson, MS | 1 |
| Rapp, UR; Reed, JC; Tonks, NK; Turner, BC | 1 |
| Atkinson, TP; Hohman, RJ; Lee, CW; Rhee, SG | 1 |
| Birge, RB; Cantley, LC; Fajardo, JE; Hanafusa, H; Reichman, C; Shoelson, SE; Songyang, Z | 1 |
| Di Salvo, J; Lauer, J; Semenchuk, LA | 1 |
| Davis, JP; Van Etten, RL; Zhou, MM | 1 |
| Aharoni, D; Amsterdam, A; Dantes, A | 1 |
| de Jonge, HR; Edixhoven, MJ; Tertoolen, LG; Tilly, BC; van den Berghe, N | 1 |
| Beaven, MA; Santini, F | 1 |
| Funayama, A; Katoh, S; Kohno, H; Ohkubo, Y | 1 |
| Dombrádi, V; Ferber, E; Gergely, P; Goldman, R; Szücs, K; Zor, U | 1 |
| Breu, J; Petryniak, MA; Slack, BE; Srivastava, K; Wurtman, RJ | 1 |
| Geiger, B; Michalides, R; Volberg, T | 1 |
| Baldi, E; Bonaccorsi, L; Forti, G; Luconi, M | 1 |
| Haynes, PA; Medh, JD; Weigel, PH | 1 |
| Abboud, HE; Biswas, P; Choudhury, GG; Fouqueray, B; Grandaliano, G; Wenzel, UO | 1 |
| Inazu, T; Nagai, K; Yamamura, H | 1 |
| Cerione, RA; Gamett, DC | 1 |
| Luber, K; Siess, W | 1 |
| Buckley, BJ; Whorton, AR | 1 |
| Hallett, MB; Lloyds, D | 1 |
| Cooper, JA; Durden, DL; Michel, BR; Rosen, H | 1 |
| Scott, RE; Wang, H | 1 |
| Chiasson, JL; D'Onofrio, F; Le, MQ; Srivastava, AK | 1 |
| Kaczmarek, LK; Wilson, GF | 1 |
| Bergamaschi, G; Cazzola, M; Danova, M; Lucotti, C; Ponchio, L; Rosti, V | 1 |
| Bianchini, L; Grinstein, S; Todderud, G | 1 |
| Blake, RA; Walker, TR; Watson, SP | 1 |
| Capolongo, L; Ciomei, M; Geroni, C; Grandi, M; Melegaro, G; Pastori, W; Pennella, G | 1 |
| Burns, DM; Kawase, T; Ogata, S; Orikasa, M | 1 |
| Penta, K; Sawyer, ST | 1 |
| Bhatia, M; Kirkland, JB; Meckling-Gill, KA | 1 |
| Bedzyk, WD; Cambier, JC; Campbell, KS | 1 |
| Eckerskorn, C; Kirchgessner, H; Marie-Cardine, A; Meuer, SC; Schraven, B | 1 |
| Branton, PE; Fournel, M; Lee, JM; Veillette, A | 1 |
| Hase, H; Hirayama, E; Kim, J; Nakano, Y | 1 |
| Saito, Y; Takagi, J | 1 |
| Burridge, K; Nelson, A | 1 |
| Di Salvo, J; Kaplan, N | 1 |
| Chang, ST; Yung, BY | 1 |
| Hallett, MB; Lloyds, D; Neville, N | 1 |
| Harbon, S; Leiber, D; Palmier, B | 1 |
| Egashira, K; Imada, C; Kishimoto, T; Nakaike, R; Owada, MK; Shimokawa, H; Shiraishi, T; Takeshita, A; Tokunaga, O; Yasutake, H | 1 |
| Cossins, AR; Weaver, YR | 1 |
| Fadool, DA; Holmes, TC; Levitan, IB | 1 |
| Auberger, P; Baeuerle, PA; Farahifar, D; Imbert, V; Livolsi, A; Mueller-Dieckmann, C; Pahl, HL; Peyron, JF; Rossi, B; Rupec, RA; Traenckner, EB | 1 |
| Hudson, LD; Ranjan, M | 1 |
| Jänne, OA; Palvimo, JJ; Reinikainen, P | 1 |
| Lebakken, CS; McCarthy, J; Ott, VL; Rapraeger, AC; Reiland, J; Yeaman, C | 1 |
| Fan, R; García-Cardeña, G; Liu, J; Sessa, WC; Stern, DF | 1 |
| Han, JD; Rubin, CS | 1 |
| Ballmer-Hofer, K; Meili, R | 1 |
| Aggarwal, BB; Darnay, BG; Singh, S | 1 |
| Begum, N; Ragolia, L | 1 |
| Atkinson, TP; Yang, Q | 1 |
| Fujimoto, S; Hayakawa, T; Kawakami, N; Shimohama, S; Sumida, Y | 1 |
| Austin, CD; Shields, D | 1 |
| Chen, K; Cohen, S; Ruff, SJ | 1 |
| Fanburg, BL; Lee, SL; Wang, WW | 1 |
| Beauchemin, N; Chow, B; Daniels, E; Kunath, T; Robitaille, J; Turbide, C; Veillette, A | 1 |
| Llinás, R; Mohammadi, M; Moreno, H; Schlessinger, J; Sugimori, M | 1 |
| Halldórsson, H; Helgadóttir, A; Kjeld, M; Magnúsdóttir, K; Thorgeirsson, G | 1 |
| Ayalon, O; Geiger, B | 1 |
| Baylink, DJ; Graves, LM; Lau, KH; Wu, LW; Yoon, HK | 1 |
| Carpenter, G; Davidson, M; Guo, DF; Inagami, T; Xu, Y | 1 |
| Hirayama, E; Isobe, A; Kim, J; Nishioka, M; Okamoto, H | 1 |
| Brisseau, GF; Cheung, PY; Dackiw, AP; Grinstein, S; McGilvray, ID; McGuire, JA; Nathens, AB; Romanek, R; Rotstein, OD | 1 |
| Kasahara, T; Kuno, K; Matsushima, K; Mukaida, N; Sonoda, Y; Yamaguchi, Y | 1 |
| Corbett, SA; Schwarzbauer, JE | 1 |
| Fink, BD; Grunwald, GB; Lee, MM | 1 |
| Aggarwal, BB; Darnay, BG | 1 |
| Bourgoin, S; Harbour, D; Marcil, J; Naccache, PH | 1 |
| Hauser, M; Winkelhaus, S | 1 |
| Acuto, O; Bottomly, K; Farber, DL | 1 |
| Albelda, SM; DeLisser, HM; Famiglietti, J; Sun, J | 1 |
| Berg, LJ; Bunnell, SC; Heyeck, SD; Wilcox, HM | 1 |
| Eriksson, JW; Jansson, PA; Posner, BI; Smith, U; Yu, ZW | 1 |
| Baker, RD; Baker, SS; Gupta, A; Holycross, M; Rao, RK | 1 |
| Dugué, B; Ekokoski, E; Törnquist, K | 1 |
| Alava, MA; Bonvini, E; DeBell, KE; Graham, L; Laborda, J; Rellahan, BL; Stoica, B | 1 |
| Basson, MD; Emenaker, NJ; Rashid, Z | 1 |
| Chambaz, EM; Chinn, A; Feige, JJ; Gaillard, I; Vilgrain, I | 1 |
| Hsu, CP; Mai, XY; Sheu, JC; Yang, CC; Yang, SD | 1 |
| Castle, JD; Wu, TT | 1 |
| Carvalho, CR; Costa, FF; Saad, MJ; Saad, ST; Terra, HT; Vicentin, DL | 1 |
| Brown, CL; Carpenter, G; Dempsey, PJ; Rudolph-Owen, LA; Vecchi, M | 1 |
| Blank, U; Blumberg, PM; Rivera, J; Song, JS; Swann, PG; Szallasi, Z | 1 |
| Fadool, DA; Levitan, IB | 1 |
| Arpin, M; Crepaldi, T; Grisendi, S | 1 |
| Eichel-Streiber, CV; Jakobs, KH; Olesch, S; Ott, S; Rümenapp, U; Schmidt, M | 1 |
| Kato, M; Kita, H; Morikawa, A; Tokuyama, K | 1 |
| Eisen, AZ; Li, L; Seltzer, JL; Sturman, E | 1 |
| al-Hassani, M; Natarajan, V; Scribner, WM; Vepa, S | 1 |
| Leu, TH; Maa, MC | 1 |
| Exton, JH; Kim, EG; Min, DS | 1 |
| Dunah, AW; Wolfe, BB; Yasuda, RP | 1 |
| Lazo, JS; Rice, RL; Settineri, CE; Vogt, A; Wipf, P; Yokokawa, F; Yokokawa, S | 1 |
| Falet, H; Pain, S; Rendu, F | 1 |
| Daniels, KJ; Hay, ED; Kim, K | 1 |
| Döring, F; Karschin, A; Wischmeyer, E | 1 |
| Reth, M; Wienands, J; Zhang, Y; Zürn, C | 1 |
| Fedinec, A; Leffler, CW; Parfenova, H | 1 |
| Evans, GJ; Pocock, JM | 1 |
| Gresser, MJ; Huyer, G; Johnson, NA; Skorey, KI | 1 |
| Albanell, J; Arribas, J; Baselga, J; Codony-Servat, J; Lopez-Talavera, JC | 1 |
| Cavalieri, E; Colasanti, M; Fabrizi, C; Lauro, GM; Mariotto, S; Menegazzi, M; Persichini, T; Suzuki, H | 1 |
| Castan, I; Degerman, E; Manganiello, V; Wijkander, J | 1 |
| Burns, DM; Kawase, T; Oguro, A; Orikasa, M | 1 |
| Buckley, CD; Cody, AJ; Douglas, M; Freeman, SD; Simmons, DL; Taylor, VC | 1 |
| Kwiatkowska, K; Sobota, A | 1 |
| McDonald, TF; Ogura, T; Shuba, LM | 1 |
| Abboud, HE; Bardgette, J; Choudhury, GG | 1 |
| Boscá, L; Castrillo, A; Díaz-Guerra, MJ; Martín-Sanz, P | 1 |
| Feng, L; Liao, J; Omary, MB; Zhou, X | 1 |
| Bedoya, FJ; Camacho, MJ; Carballo, M; Conde, J; Conde, M; El Bekay, R; Martín-Nieto, J; Monteseirín, J; Sobrino, F | 1 |
| Lee, RS; Mukhopadhyay, NK; Narsimhan, RP; Neel, BG; Roberts, TM; Xia, K | 1 |
| Castranova, V; Chen, F; Demers, LM; Ding, M; Lu, Y; Shi, X; Vallyathan, V | 1 |
| Béguin, P; Carranza, ML; Caverzasio, J; Favre, H; Féraille, E; Geering, K; Gonin, S; Martin, PY; Pedemonte, C; Rousselot, M | 1 |
| Araki, S; Ishibashi, S; Nishimura, Y; Okamura, N; Sakai, M; Sakai, T; Yamaguchi, M | 1 |
| Scheving, LA; Thomas, JR; Zhang, L | 1 |
| Sakaki, Y; Sugioka, M; Yamashita, M; Zhou, WL | 1 |
| Goldstein, BJ; Harada, S; Jarett, L; Smith, JA; Solow, BT; White, MF | 1 |
| El-Shazly, A; Ishikawa, T; Masuyama, K; Suda, T; Yamaguchi, N | 1 |
| Chen, K; Cohen, S; Furge, LL | 1 |
| del Mont Llosas, M; Fabre, M; García de Herreros, A; Gómez, S; Lloreta, J; Roura, S; Verdú, J | 1 |
| Ferrell, JE; Sohaskey, ML | 1 |
| Aoki, T; Fujimoto, T; Nomura, R | 1 |
| Blanchetot, C; Buist, A; den Hertog, J | 1 |
| Atkinson, JP; Chan, AC; Liszewski, MK; Wang, G | 1 |
| Hill, MA; Murphy, TV; Spurrell, BE | 2 |
| Sui, X; Xu, F; Xu, M; Zhao, R; Zhao, ZJ | 1 |
| Brooks, SR; Carter, RH; Li, X; Volanakis, EJ | 1 |
| Aggarwal, BB; Manna, SK; Mukhopadhyay, A | 1 |
| Kang, KR; Kim, CW | 1 |
| Ilsley, JL; James, M; Nuttall, A; Ottersbach, K; Sudol, M; Tinsley, JM; Winder, SJ | 1 |
| Araki, Y; Sendo, F; Yu, Y | 1 |
| Kitamura, T; Murayama, T; Nomura, Y | 1 |
| Hug, A; Kriz, W; Mundel, P; Pixley, FJ; Reiser, J; Smoyer, WE; Stanley, ER | 1 |
| Becker, KF; Candidus, S; Feller, S; Handschuh, G; Höfler, H; Hutzler, P; Luber, B; Mentele, E; Voss, J | 1 |
| Carvalho, E; Rondinone, C; Smith, U | 1 |
| Decker, SJ; Prasad, N; Topping, RS; Zhou, D | 1 |
| Dong, LQ; Hu, D; Langlais, P; Liu, F | 1 |
| Grüning, C; Rehder, D | 1 |
| Müller, R; Reth, M; Wienands, J | 1 |
| Mackay, K; Mochly-Rosen, D | 1 |
| Abella, A; Camps, M; Carpéné, C; Casamitjana, R; Castan, I; Degerman, E; Enrique-Tarancón, G; Marti, L; Morin, N; Palacín, M; Testar, X; Zorzano, A | 1 |
| Jin, S; Lane, MD; Liao, K; Qiu, Z; Wu, J; Zhai, B | 1 |
| Fujita, M; Uezato, T; Wu, YX | 1 |
| Abraham, WC; Coussens, CM; Ireland, DR; Williams, JM | 1 |
| Eichler, DC; Flam, BR; Hellermann, GR; Solomonson, LP | 1 |
| Blaikie, P; Dans, M; Gagnoux-Palacios, L; Giancotti, FG; Klein, S; Mariotti, A | 1 |
| Baba, A; Hashimoto, H; Koyama, Y; Matsuda, T; Yoshioka, Y | 1 |
| Castranova, V; Kang, JL; Lee, HS; Pack, IS | 1 |
| Bouzahzah, B; Bregman, DB; Campos-Gonzalez, R; Galbiati, F; Iyengar, P; Lee, H; Lisanti, MP; Lublin, DM; Pestell, RG; Scherer, PE; Volonte, D; Wilson, MT | 1 |
| Catalano, PM; Friedman, JE; Ishizuka, T; Shao, J; Yamashita, H | 1 |
| Garcia, JG; Natarajan, V; Patterson, CE; Schaphorst, KL; Vepa, S; Verin, AD | 1 |
| Xu, F; Zhao, ZJ | 1 |
| Kramer, DL; Pederson, TM; Rondinone, CM | 1 |
| Ballard, G; Harrington, EO; Newton, J; Rounds, S; Smeglin, A | 1 |
| Chen, J; Efendic, S; Gogg, S; Ostenson, C; Smith, U | 1 |
| Imamura, T; Kaul, SC; Loupatov, A; Misono, T; Mizukoshi, E; Munekata, E; Suzuki, M; Wadhwa, R | 1 |
| Catarzi, S; Favilli, F; Iantomasi, T; Vincenzini, MT | 1 |
| Aizu-Yokota, E; Hasegawa, M; Kasahara, T; Momoi, T; Sakurai, S; Sonoda, Y; Yamamoto, D | 1 |
| Masui, H; Wakabayashi, I | 1 |
| Albert, AP; Aromolaran, AS; Large, WA | 1 |
| Biden, TJ; Blewitt, M; Kelly, MM; Mitchell, CJ; Wilson, JR | 1 |
| Gamero, AM; Larner, AC | 1 |
| Davis, B; Hu, MC; Ling, P; Meyer, CF; Redmond, LP; Rich, RR; Shui, JW; Tan, TH; Wange, RL | 1 |
| Arman, M; Gimferrer, I; Lozano, F; Padilla, O; Places, L; Simarro, M; Vilà, JM; Vives, J | 1 |
| Feldman, RD; Ferguson, SS; Kelvin, DJ; Litchfield, DW; Tan, CM | 1 |
| Benes, C; Soltoff, SP | 1 |
| Anastasiadis, P; Böhmer, FD; Keilhack, H; Mariner, DJ; Reynolds, AB; Wang, J | 1 |
| Heldin, CH; Ostman, A; Persson, C; Shimizu, A | 1 |
| Kim, K; Lee, KY | 1 |
| Chen, W; Frasch, WD | 1 |
| Brazil, DP; Hemmings, BA; Hess, D; Hill, MM; Hofsteenge, J; Park, J | 1 |
| Chan, AC; Engels, N; Longnecker, R; Merchant, M; Pappu, R; Wienands, J | 1 |
| Cui, ZC; Li, Y; Pei, L; Zhang, GY; Zhu, ZM | 1 |
| Ishibashi, T; Nishio, M; Yoshida, J | 1 |
| Hsueh, WA; Kim, S; Kintscher, U; Kuroki, T; Law, RE; Liu, Z; Ohba, M; Schönthal, AH; Wakino, S; Yin, F | 1 |
| Jaso-Friedmann, L; Leary, JH; Ruiz, J | 1 |
| Balaian, L; Ball, ED | 1 |
| Barisone, I; Di Mauro, D; Fumagalli, G; Sala, C; Sava, A | 1 |
| Akiba, S; Hayama, M; Kitatani, K; Sato, T | 1 |
| Hu, P; O'Keefe, EJ; Rubenstein, DS | 1 |
| Abramson, J; Fridkin, M; Pecht, I; Xu, R | 1 |
| Guerrah, A; Xu, F; Xu, MJ; Zeng, F; Zhao, R; Zhao, ZJ | 1 |
| Guo, GG; Kumar, V; Patel, K; Sehgal, PB; Shah, M | 1 |
| Ahn, BH; Chang, JS; Choi, JY; Chung, KC; Hahn, SJ; Jo, YH; Kim, MS; Kim, SY; Kwon, TK; Lee, MY; Lee, YH; Min, DS; Rhim, H; Sung, YM; Wolozin, B; Yoon, SH | 1 |
| D'Adamio, L; Pelicci, G; Pelicci, PG; Roncarati, R; Tarr, PE | 1 |
| Ekman, S; Engström, U; Heldin, CH; Kallin, A; Rönnstrand, L | 1 |
| de Souza, W; Morgado-Díaz, JA | 1 |
| Dong, LQ; Guo, Z; Lim, MA; Liu, F; Ramos, FJ; Richardson, A; Strong, R; Wick, MJ | 1 |
| Chavkin, C; Ippolito, DL; Rogalski, SL; Temkin, PA | 1 |
| Denhez, F; Goetinck, PF; Wilcox-Adelman, SA | 1 |
| Lee, H; Lisanti, MP; Park, DS; Scherer, PE; Schwartz, PE; Wang, XB | 1 |
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| Amachi, T; Imanaka, T; Kasiwayama, Y; Kioka, N; Kurisu, M; Matsuo, M; Morita, M; Tanabe, K; Tanaka, AR; Ueda, K | 1 |
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| Engelhardt, JF; Fan, C; Yang, J | 1 |
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| Dobashi, H; Ishida, H; Ishida, T; Kitanaka, A; Kubo, A; Kubota, Y; Matsumoto, A; Ohnishi, H; Tanaka, T; Tokuda, M; Waki, M | 1 |
| Döppler, H; Johannes, FJ; Storz, P; Toker, A | 1 |
| Guo, G; Kumar, V; Murray, WC; Sehgal, PB | 1 |
| Horwitz, J; Kobayashi, MS; Maglio, J; Mehta, S; Sipple, AM | 1 |
| Cai, D; Dhe-Paganon, S; Lee, J; Melendez, PA; Shoelson, SE | 1 |
| Akkerman, JW; Ferreira, IA; Gorter, G; Relou, IA; van Rijn, HJ | 1 |
| Freund, GG; O'Connor, JC | 1 |
| Bustelo, XR; Gutkind, JS; Marinissen, MJ; Servitja, JM; Sodhi, A | 1 |
| Biagioni, C; Catarzi, S; Favilli, F; Giannoni, E; Iantomasi, T; Vincenzini, MT | 1 |
| Chang, YH; Chen, CW; Lin, WW; Tsi, CJ | 1 |
| Berkowitz, P; Hu, P; O'Keefe, EJ; Rubenstein, DS | 1 |
| Band, H; Band, V; Druker, BJ; Duan, L; Miura-Shimura, Y; Rao, NL; Reddi, AL; Rottapel, R; Shimura, H; Tsygankov, A | 1 |
| Han, DH; Hansen, PA; Holloszy, JO; Hucker, KA; Nolte, LA | 1 |
| Lemke, P; Marg, A; Meyer, T; Vinkemeier, U; Wiesner, B | 1 |
| Jäck, HM; Mielenz, D; Ruschel, A; Vettermann, C | 1 |
| Kundu, GC; Mahabeleshwar, GH | 1 |
| Krajewski, JL; Kramer, RH; Luetje, CW | 1 |
| Chen, ST; Chou, CM; Hsiao, PW; Hsu, YL; Huang, CJ; Lien, JC; Lin, CC; Tsai, SC; Wang, YM | 1 |
| Alvarez, SE; Ciuffo, GM; Fuentes, LB | 1 |
| Namiki, H; Suzuki, K; Takahashi, H | 1 |
| Duncker, DJ; Gho, BC; Gho, CC; Kazim, S; Liem, DA; Manintveld, OC; Verdouw, PD | 1 |
| Lindquist, M; Ponnappan, S; Ponnappan, U; Uken-Trebilcock, G | 1 |
| Aitken, RJ; Baker, MA; Gunasekera, T; Hetherington, L; Mate, KE; Rodger, JC; Sidhu, KS; Veal, D | 1 |
| Groopman, JE; Wang, JF; Zhang, X | 1 |
| Cheong, C; Cho, JM; Jee, J; Jeon, YH; Kim, KA; Lee, C; Lee, TG; Lee, W; Ro, S; Sheen, MR; Song, JS; Yamazaki, T | 1 |
| Brummer, T; Elis, W; Huber, M; Reth, M | 1 |
| Collett, VJ; Collingridge, GL | 1 |
| Chattopadhyay, S; Kinter, M; McCue, B; Sadhukhan, R; Santhamma, KR; Sen, I | 1 |
| Beaven, MA; Chahdi, A; Choi, WS; Han, JW; Her, E; Hiragun, T; Kim, HP; Kim, YM; Lee, JH | 1 |
| Ikehara, SK; Ikehara, Y; Paulson, JC | 1 |
| Harayama, H; Miyake, M; Sasaki, K | 1 |
| Bertagnolli, MM; Carothers, AM; Hunt, DH; Javid, SH; Moran, AE; Redston, M | 1 |
| Mancini, A; Niedenthal, R; Ohrt, T; Tamura, T | 1 |
| Bhat, GJ; Samikkannu, T; Thekkumkara, TJ; Thomas, JJ | 1 |
| Bellón, T; Kitzig, F; López-Botet, M; Martínez-Barriocanal, A; Sayós, J | 1 |
| Lee, YM; Omary, MB; Salemi, MR; Strnad, P; Tao, GZ; Zhou, Q | 1 |
| Bertagnolli, MM; Carothers, AM; Moran, AE; Redston, M; Weyant, MJ | 1 |
| Jebe, E; Petrunkina, AM; Töpfer-Petersen, E | 1 |
| Dunah, AW; Hoogenraad, CC; Hueske, E; Jaworski, J; Liu, G; Pak, DT; Sheng, M; Simonetta, A; Wyszynski, M | 1 |
| Cho, CH; Leitzell, K; Lester, RA; Meleth, AD; Quick, MW; Song, W; Teo, E | 1 |
| Ferrani-Kile, K; Leslie, SW | 1 |
| Judah, JD; Lo, LC; Thomas, GM; Webb, RJ | 1 |
| Al-Shaldi, H; Anderie, I; Evers, K; Hofer, HW; Köhl, A; Krause, E; Latas, A; Schmid, A; Schulz, I; Sternfeld, L | 1 |
| Hasegawa, A; Hatano, Y; Kakutani, T; Mizumoto, K; Ogawa, K; Yu, J | 1 |
| Hu, D; Liu, L; Zhou, R | 1 |
| Gross, S; Meurer, S; Müller-Esterl, W; Pioch, S | 1 |
| Courjault-Gautier, F; Felley-Bosco, E; Hausel, P; Latado, H | 1 |
| Boustead, JN; Cooper, JC; Yu, CL | 1 |
| Brady, MJ; Makinen, MW; Mustafi, D; Ou, H; Yan, L | 1 |
| Chow, CW; Downey, GP; Herrera Abreu, MT; Hong, O; McCulloch, CA; Suzuki, T; Vachon, E; Villar, J; Wang, Q; Wang, Y | 1 |
| Mädler, HJ; Schnittler, HJ; Seebach, J; Wojciak-Stothard, B | 1 |
| Huang, J; McNaughton, PA; Zhang, X | 1 |
| Champoux, JJ; Davies, DR; Hol, WG; Interthal, H; Mushtaq, A | 1 |
| Doi, Y; Enomoto, K; Nishikawa, Y; Ohi, N; Omori, Y; Tokairin, T; Yamamoto, Y | 1 |
| Han, D; Wang, XT; Xu, TL; Yin, XH; Zhang, GY; Zhang, QG | 1 |
| Arruebo, MP; Grasa, L; Murillo, MD; Plaza, MA | 1 |
| Ebel, M; Rehder, D | 1 |
| Hovens, CM; I, ST; Lock, P; Schieb, H; Straffon, AF; Stylli, SS | 1 |
| Al-Shaldi, H; Anderie, I; Hofer, HW; Krause, E; Magg, T; Schmid, A; Schreiner, D; Schulz, I; Sternfeld, L | 1 |
| Boeri Erba, E; Bunkenborg, J; Cabodi, S; Defilippi, P; Di Stefano, P; Jensen, ON; Matthiesen, R; Schulze, WX; Tarone, G | 1 |
| Hristov, KK; Knox, KA; Mitev, VI | 1 |
| Chen, PY; Chi, WC; Chien, PS; Huang, DD; Huang, HJ; Hung, WC; Yeh, CM | 1 |
| Band, H; Cook, SJ; Wiggins, CM | 1 |
| Benitez, MJ; Bhat, RV; Díaz-Nido, J; Garrido, JJ; Gimenez-Cassina, A; Simón, D; Wandosell, F | 1 |
| Göbel, TW; Hanczaruk, MA; Schmitt, FC; Schmitt, R; Viertlboeck, BC | 1 |
| Dráber, P; Dráberová, L; Korb, J; Lebduska, P; Smrz, D | 1 |
| An, X; Cowburn, D; Cui, P; Debnath, AK; Guo, X; Hossain, S; Kotula, L; Warner, B; Xiong, X; Xu, R | 1 |
| Crèvecoeur, J; Gloire, G; Merville, MP; Piette, J | 1 |
| Kajiho, H; Katada, T; Kontani, K; Minoda, T; Nakagawa, S; Sakurai, K; Yoshikawa, M | 1 |
| Hosoi, T; Kume, A; Nomura, Y; Okuma, Y; Ozawa, K; Saito, A | 1 |
| Brown, AC; Mawby, WJ; Toye, AM; Williamson, RC | 1 |
| Bui, HT; Hwang, KC; Kim, JH; Miyano, T; Van Thuan, N; Wakayama, T | 1 |
| Hüttemann, M; Lee, I; Pecina, P; Pecinova, A; Salomon, AR; Samavati, L; Yu, K | 1 |
| Imai, S; Isoya, E; Kumagai, K; Matsusue, Y; Matsuura, H; Okumura, N; Toyoda, F | 1 |
| Hwang, SA; Jang, SH; Karnik, SS; Kim, M; Kim, MS; Lee, C; Yun, SH | 1 |
| Fernow, I; Siehoff-Icking, A; Tikkanen, R; Tomasovic, A | 1 |
| Enkavi, G; Feng, J; Gehrig, P; Lucchinetti, E; Roschitzki, B; Schaub, MC; Tajkhorshid, E; Wang, Y; Zaugg, K; Zaugg, M | 1 |
| Dong, MQ; Lau, CP; Li, GR; Sun, HY; Tang, Q; Tse, HF | 1 |
| Chen, J; Ghosh, K; Gibb, B; Gupta, K; Sharp, R; Van Duyne, GD | 1 |
| Gu, SH; Lin, JL | 1 |
| Chung, SH; Couraud, PO; Gillies, MC; Li, S; Romero, IA; Shen, W; Stayt, J; Su, T; Weksler, B; Zhu, L | 1 |
| Campanella, E; Ferru, E; Giger, K; Grey, J; Low, PS; Pantaleo, A; Ritchie, K; Turrini, F; Vono, R | 1 |
| Bordin, L; Calò, LA; Clari, G; Dal Maso, L; Davis, PA; Pagnin, E; Pessina, AC; Rossi, GP | 1 |
| Dong, MQ; Lau, CP; Li, GR; Sun, HY; Tse, HF; Wu, W; Wu, XG | 1 |
| Hashizume, H; Kamio, N; Matsushima, K; Muromachi, K; Nakao, S; Narita, T | 1 |
| Boutterin, MC; Doly, S; Faure, C; Gervasi, N; Mazot, P; Tremblay, ML; Vigny, M | 1 |
| Bencze, G; Cohen, P; Krishnan, N; Tonks, NK | 1 |
| Hishinuma, S; Mita, M; Nakagawa, J; Shoji, M; Sutherland, C; Tanaka, H; Walsh, MP; Yanagihara, H | 1 |
| den Hertog, J; Knapp, S; Liskamp, RM; Overvoorde, J; Ruijtenbeek, R; van Ameijde, J | 1 |
| Aldasoro, M; Fernández, N; Ferrero, E; Ferrero, JL; García-Villalón, AL; García-Villar, O; Granado, M; Hidalgo, M; Mauricio, MD; Monge, L; Vila, JM | 1 |
| Caruso, JA; Caruthers, NJ; Dombkowski, A; Gill, R; Rosenspire, AJ; Stemmer, PM | 1 |
| Cullen, S; Ponnappan, S; Ponnappan, U | 1 |
| Chiang, CY; Cho, CY; Huang, CY; Jeng, WY; Kan, WC; Lee, TH; Ling, P; Lu, TJ; Lu, TL; Weng, YP; Wu, JB | 1 |
| Carruthers, N; Caruso, JA; Gill, R; Rosenspire, A; Shin, N; Stemmer, PM | 1 |
| Kim, UJ; Lee, BH; Lee, KH | 1 |
| Ayewoh, EN; Chothe, PP; Czuba, LC; Swaan, PW | 1 |
1 trial(s) available for vanadates and tyrosine
| Article | Year |
|---|---|
Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects.
Topics: Adipose Tissue; Adult; Animals; Biological Transport; Cell Fractionation; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Humans; Hydrogen Peroxide; Immunoblotting; Insulin; Insulin Resistance; Membrane Proteins; Obesity; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Temperature; Tyrosine; Vanadates; Wheat Germ Agglutinins | 1990 |
413 other study(ies) available for vanadates and tyrosine
| Article | Year |
|---|---|
Inhibition of tyrosine phosphorylation potentiates substrate-induced neurite growth.
Topics: Animals; Brain; Catechols; Cell Adhesion Molecules, Neuronal; Cells, Cultured; Chick Embryo; Culture Media; Extracellular Matrix Proteins; Genistein; Isoflavones; Nerve Tissue Proteins; Neurites; Neurons; Nitriles; Phenols; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Signal Transduction; Tyrosine; Tyrphostins; Vanadates | 1992 |
Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation.
Topics: Animals; Calcium; Cell Line; Cells, Cultured; Cytosol; Flow Cytometry; Gene Expression Regulation; Humans; Hydrogen Peroxide; Immunoblotting; Kinetics; Lymphocyte Activation; Mice; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Interleukin-2; RNA; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1992 |
The SH2- and SH3-containing Nck protein transforms mammalian fibroblasts in the absence of elevated phosphotyrosine levels.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Line; Cell Transformation, Neoplastic; Fibroblasts; Humans; Immunoblotting; Ligands; Mice; Mice, Inbred BALB C; Oncogene Protein pp60(v-src); Oncogene Protein v-crk; Oncogene Proteins; Phosphotyrosine; Rats; Retroviridae Proteins, Oncogenic; Sulfhydryl Compounds; Tyrosine; Vanadates | 1992 |
Zymosan-triggered tyrosine phosphorylation in mouse bone-marrow-derived macrophages is enhanced by respiratory-burst priming agents.
Topics: Animals; Benzoquinones; Bone Marrow Cells; Cells, Cultured; Cinnamates; Enzyme Activation; In Vitro Techniques; Interferon-gamma; Lactams, Macrocyclic; Lipopolysaccharides; Macrophages; Mice; Mice, Inbred CBA; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Respiratory Burst; Rifabutin; Sulfides; Tumor Necrosis Factor-alpha; Tyrosine; Vanadates; Zymosan | 1992 |
The insulinomimetic agents H2O2 and vanadate stimulate tyrosine phosphorylation of potential target proteins for the insulin receptor kinase in intact cells.
Topics: Animals; CHO Cells; Cricetinae; Hydrogen Peroxide; In Vitro Techniques; Insulin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Transfection; Tyrosine; Vanadates | 1992 |
Nerve growth factor mediates signal transduction through trk homodimer receptors.
Topics: 3T3 Cells; Animals; Cell Line; Cysteine; Humans; Kinetics; Macromolecular Substances; Methionine; Mice; Nerve Growth Factors; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins; Proto-Oncogenes; Rats; Receptor, trkA; Receptors, Nerve Growth Factor; Recombinant Proteins; Signal Transduction; Transfection; Tyrosine; Vanadates | 1992 |
The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions.
Topics: Actins; Animals; Avian Sarcoma Viruses; Blotting, Western; Cell Adhesion; Cell Adhesion Molecules; Cell Transformation, Viral; Cells, Cultured; Chickens; Dogs; Fluorescent Antibody Technique; Hydrogen Peroxide; Lens, Crystalline; Microscopy, Fluorescence; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine; Vanadates; Vinculin | 1992 |
Cyclin A- and cyclin B-dependent protein kinases are regulated by different mechanisms in Xenopus egg extracts.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Cations, Divalent; CDC2 Protein Kinase; Cyclins; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Kinetics; Molecular Sequence Data; Ovum; Phosphorylation; Protamine Kinase; Protein Kinases; Tyrosine; Vanadates; Xenopus | 1992 |
Interleukin 3, granulocyte-macrophage colony-stimulating factor, and transfected erythropoietin receptors mediate tyrosine phosphorylation of a common cytosolic protein (pp100) in FDC-ER cells.
Topics: Animals; Cell Division; Cell Line; Cell Membrane; Cytosol; Erythropoietin; Granulocyte-Macrophage Colony-Stimulating Factor; Interleukin-3; Kinetics; Mice; Molecular Weight; Peptide Mapping; Phosphopeptides; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, Erythropoietin; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Receptors, Interleukin-3; Subcellular Fractions; Transfection; Tyrosine; Vanadates | 1992 |
Lipopolysaccharide- and interferon-gamma-induced expression of hck and lyn tyrosine kinases in murine bone marrow-derived macrophages.
Topics: Animals; Bone Marrow Cells; Gene Expression; Interferon-gamma; Lipopolysaccharides; Macrophage Activation; Macrophages; Mice; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Respiratory Burst; RNA, Messenger; src-Family Kinases; Tyrosine; Vanadates | 1992 |
Zinc causes tyrosine phosphorylation of hippocampal p60c-src.
Topics: Adenosine Triphosphate; Animals; Cyanogen Bromide; Hippocampus; Male; Membrane Proteins; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Inbred Strains; Tyrosine; Vanadates; Zinc | 1992 |
Insulin and orthovanadate stimulate multiple phosphotyrosine-containing serine kinases.
Topics: Amino Acid Sequence; Animals; Cytosol; DNA; Enzyme Activation; Fibroblasts; Humans; Insulin; Isoenzymes; Mice; Molecular Sequence Data; Molecular Weight; Oligopeptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Receptor, Insulin; Recombinant Proteins; Stimulation, Chemical; Tyrosine; Vanadates | 1992 |
Alteration of phosphotyrosine-containing proteins at the early stage of erythroid differentiation of mouse erythroleukemia (MEL) cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Electrophoresis, Polyacrylamide Gel; Kinetics; Leukemia, Erythroblastic, Acute; Leukemia, Experimental; Mice; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Sulfuric Acid Esters; Tyrosine; Vanadates | 1992 |
Insulin and insulinomimetic agents induce activation of phosphatidylinositol 3'-kinase upon its association with pp185 (IRS-1) in intact rat livers.
Topics: Animals; Blotting, Western; Enzyme Activation; Hydrogen Peroxide; Insulin; Insulin Receptor Substrate Proteins; Liver; Macromolecular Substances; Male; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine; Vanadates | 1992 |
Kinase inhibition by a phosphorylated peptide corresponding to the major insulin receptor autophosphorylation domain.
Topics: Amino Acid Sequence; Binding, Competitive; Immunosorbent Techniques; Molecular Sequence Data; Peptide Fragments; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Conformation; Protein-Tyrosine Kinases; Receptor, Insulin; Tyrosine; Vanadates | 1992 |
Okadaic acid and vanadate inhibit collagen-induced platelet aggregation; the functional relation of phosphatases on platelet aggregation.
Topics: Adenosine Triphosphate; Blood Platelets; Collagen; Depression, Chemical; Ethers, Cyclic; Humans; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Platelet Aggregation; Platelet Aggregation Inhibitors; Protein Phosphatase 1; Serotonin; Tyrosine; Vanadates | 1992 |
Cyclin A potentiates maturation-promoting factor activation in the early Xenopus embryo via inhibition of the tyrosine kinase that phosphorylates cdc2.
Topics: Amino Acid Sequence; Animals; CDC2 Protein Kinase; Cyclins; Enzyme Activation; Ethers, Cyclic; Humans; Interphase; Maturation-Promoting Factor; Models, Biological; Molecular Sequence Data; Okadaic Acid; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine; Vanadates; Xenopus | 1992 |
PDGF induces tyrosine phosphorylation in osteoblast-like cells: relevance to mitogenesis.
Topics: Animals; Cell Line; Genistein; Isoflavones; Mitosis; Osteoblasts; Phosphorylation; Platelet-Derived Growth Factor; Thymidine; Tyrosine; Vanadates | 1992 |
Activation of signal transduction in platelets by the tyrosine phosphatase inhibitor pervanadate (vanadyl hydroperoxide).
Topics: Actins; Adenosine Triphosphate; Alkaloids; Blood Proteins; Blotting, Western; Calcium; Catechols; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Nitriles; Phospholipids; Phosphoproteins; Phosphorylation; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Tyrosine Phosphatases; Serotonin; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrosine; Tyrphostins; Vanadates | 1992 |
Characterization of the molecular mechanism involved in the activation of hyaluronan synthetase by platelet-derived growth factor in human mesothelial cells.
Topics: Cell Membrane; Cells, Cultured; Cycloheximide; Enzyme Activation; Epithelial Cells; Epithelium; Glucuronosyltransferase; Glycosyltransferases; Humans; Hyaluronan Synthases; Kinetics; Membrane Proteins; Phosphorylation; Platelet-Derived Growth Factor; Protein Biosynthesis; Protein Kinase C; Serine; Stimulation, Chemical; Tetradecanoylphorbol Acetate; Threonine; Transferases; Transforming Growth Factor beta; Tyrosine; Vanadates; Xenopus Proteins | 1992 |
Peroxides of vanadate induce activation of phospholipase D in HL-60 cells. Role of tyrosine phosphorylation.
Topics: Adenosine Triphosphate; Cell Line; Enzyme Activation; Ethylene Glycols; GTP-Binding Proteins; Humans; Kinetics; Oxygen Consumption; Phospholipase D; Phosphorylation; Protein Kinase C; Tyrosine; Vanadates | 1992 |
Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts.
Topics: Animals; Benzoquinones; Cadherins; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Line, Transformed; Collagen; Fibroblasts; Fluorescent Antibody Technique; Gels; Immunoblotting; Lactams, Macrocyclic; Neoplasm Metastasis; Oncogene Protein pp60(v-src); Oncogenes; Phosphorylation; Quinones; Rats; Rifabutin; Tyrosine; Vanadates | 1992 |
Characterization of the tyrosine phosphorylation of calpactin I (annexin II) induced by platelet-derived growth factor.
Topics: Animals; Annexins; Blotting, Western; Calcium-Binding Proteins; Cell Line; Hydrogen-Ion Concentration; Kinetics; Membrane Proteins; Mice; Phosphatidylinositols; Phosphorylation; Platelet-Derived Growth Factor; Tyrosine; Vanadates | 1991 |
Vanadate stimulates oxygen consumption and tyrosine phosphorylation in electropermeabilized human neutrophils.
Topics: Adenosine Triphosphate; Cell Membrane Permeability; Electricity; GTP-Binding Proteins; Guanosine Diphosphate; Humans; Magnesium; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxygen Consumption; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 1990 |
Phosphotyrosine-containing lactate dehydrogenase is restricted to the nuclei of PC12 pheochromocytoma cells.
Topics: Adrenal Gland Neoplasms; Animals; Cell Line; Cell Nucleus; Chromatography, Affinity; Cytoplasm; DNA-Binding Proteins; Isoenzymes; L-Lactate Dehydrogenase; Pheochromocytoma; Phosphates; Phosphorus Radioisotopes; Phosphotyrosine; Rats; Tyrosine; Vanadates | 1990 |
Serum independence of transcription from the promoter of an avian retrovirus in v-src-transformed cells is a primary, intracellular effect of increased tyrosine phosphorylation.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Cell Transformation, Neoplastic; Cycloheximide; Kinetics; Oncogene Protein pp60(v-src); Oncogenes; Phosphorylation; Phosphotyrosine; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Temperature; Transfection; Tyrosine; Vanadates | 1990 |
Activation of permeabilized HL60 cells by vanadate. Evidence for divergent signalling pathways.
Topics: Actins; Adenosine Triphosphate; Amanitins; Calcium; Cell Membrane Permeability; Exocytosis; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Humans; Immunoblotting; Leukemia, Promyelocytic, Acute; Muramidase; NADP; Neutrophils; Oxygen Consumption; Phosphotyrosine; Polymers; Signal Transduction; Thionucleotides; Tumor Cells, Cultured; Tyrosine; Vanadates | 1990 |
Inverse correlation between tyrosine phosphorylation and collagenase production in chondrocytes.
Topics: Animals; Blood; Cartilage, Articular; Cattle; Cell Division; Goats; Microbial Collagenase; Phosphorylation; Phosphotyrosine; Proteoglycans; Rats; Tyrosine; Vanadates | 1990 |
A low-molecular weight acid phosphatase present in crystalline preparations of rabbit skeletal muscle glycogen phosphorylase b.
Topics: Acid Phosphatase; Animals; Chromatography, Gel; Hydrogen-Ion Concentration; Hydrolysis; Molecular Weight; Muscles; Nitrophenols; Organophosphorus Compounds; Phosphorylase b; Phosphotyrosine; Rabbits; Substrate Specificity; Tyrosine; Vanadates; Zinc | 1990 |
Activation of a membrane-associated phosphatidylinositol kinase through tyrosine-protein phosphorylation by naphthoquinones and orthovanadate.
Topics: 1-Phosphatidylinositol 4-Kinase; Animals; Cell Membrane; Chromatography, Affinity; Kinetics; Liver; Male; Naphthoquinones; Phosphorylation; Phosphotransferases; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Tyrosine; Vanadates | 1990 |
Cyclin B targets p34cdc2 for tyrosine phosphorylation.
Topics: Animals; Aphidicolin; CDC2 Protein Kinase; Cell Cycle; Cyclins; Diterpenes; Emetine; Fertilization; Mitosis; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Sea Urchins; Time Factors; Tyrosine; Vanadates | 1991 |
Specific proto-oncogenic tyrosine kinases of src family are enriched in cell-to-cell adherens junctions where the level of tyrosine phosphorylation is elevated.
Topics: Age Factors; Animals; Cell Adhesion; Cell Communication; Cell Membrane; Electrophoresis, Gel, Two-Dimensional; Fluorescent Antibody Technique; Genes, src; Liver; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-yes; Proto-Oncogene Proteins pp60(c-src); Rats; src-Family Kinases; Tyrosine; Vanadates | 1991 |
Distinct patterns of tyrosine phosphorylation during the life cycle of Trypanosoma brucei.
Topics: Animals; Blotting, Western; Chromatography, Ion Exchange; Eflornithine; Electrophoresis, Polyacrylamide Gel; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Trypanosoma brucei brucei; Tyrosine; Vanadates | 1991 |
Mechanism of vanadate-induced activation of tyrosine phosphorylation and of the respiratory burst in HL60 cells. Role of reduced oxygen metabolites.
Topics: Granulocytes; Humans; Leukemia, Prolymphocytic; NADP; Oxygen Consumption; Phosphorylation; Phosphotyrosine; Superoxides; Tumor Cells, Cultured; Tyrosine; Vanadates; Vanadium | 1991 |
Myeloid differentiation associated tyrosine protein kinase activity in WEHI-3B murine monomyelocytic leukemia cells.
Topics: Animals; Cell Differentiation; Cell Division; Flow Cytometry; Immunoblotting; Kinetics; Leukemia, Myelomonocytic, Acute; Mice; Neoplasm Proteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Vanadates | 1991 |
Stimulation of tyrosine kinase activity in anti-phosphotyrosine immune complexes of Swiss 3T3 cell lysates occurs rapidly after addition of bombesin, vasopressin, and endothelin to intact cells.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Antigen-Antibody Complex; Bombesin; Calcimycin; Cell-Free System; Endothelins; Gastrins; Kinetics; Mice; Molecular Sequence Data; Molecular Weight; Neuropeptides; Peptides; Phorbol 12,13-Dibutyrate; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Substrate Specificity; Tyrosine; Vanadates; Vasopressins | 1991 |
Prostatic epithelial cells in culture: phosphorylation of protein tyrosyl residues and tyrosine protein kinase activity.
Topics: Animals; Cells, Cultured; Dogs; Epithelial Cells; Epithelium; Growth Substances; Magnesium; Male; Manganese; Molecular Weight; Phosphorylation; Phosphotyrosine; Prostate; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Steroids; Subcellular Fractions; Tyrosine; Vanadates | 1991 |
Tyrosine phosphorylation selectively regulates renal cellular phosphate transport. Evidence that it mediates the stimulatory effect of insulin-like growth factor-1.
Topics: Animals; Biological Transport; Cells, Cultured; Dose-Response Relationship, Drug; Genistein; Insulin-Like Growth Factor I; Isoflavones; Kidney; Opossums; Phosphates; Phosphorylation; Protein Biosynthesis; Protein-Tyrosine Kinases; Sodium; Tyrosine; Vanadates | 1992 |
Phorbol 12-myristate 13-acetate inhibits granulocyte-macrophage colony stimulating factor-induced protein tyrosine phosphorylation in a human factor-dependent hematopoietic cell line.
Topics: Cell Line; DNA Replication; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Stem Cells; Humans; Interleukin-3; Kinetics; Phosphoprotein Phosphatases; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Thymidine; Tyrosine; Vanadates | 1991 |
Phospholipase C gamma complexes with ligand-activated platelet-derived growth factor receptors. An intermediate implicated in phospholipase activation.
Topics: Blotting, Western; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Hydrogen-Ion Concentration; Inositol Phosphates; Ligands; Phosphoproteins; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Type C Phospholipases; Tyrosine; Vanadates | 1991 |
Cyclin promotes the tyrosine phosphorylation of p34cdc2 in a wee1+ dependent manner.
Topics: Animals; Baculoviridae; Calcium-Calmodulin-Dependent Protein Kinases; CDC2 Protein Kinase; Cell Cycle Proteins; Cyclins; Humans; Moths; Mutagenesis, Site-Directed; Nuclear Proteins; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Schizosaccharomyces; Schizosaccharomyces pombe Proteins; Tyrosine; Vanadates | 1991 |
pp75: A novel tyrosine-phosphorylated protein that heralds differentiation of HL-60 cells.
Topics: Blotting, Western; Calcitriol; Cell Differentiation; Doxorubicin; Electrophoresis, Polyacrylamide Gel; Humans; Hydrogen Peroxide; Phosphoproteins; Phosphorylation; Tumor Cells, Cultured; Tyrosine; Vanadates | 1991 |
The insulinomimetic agents H2O2 and vanadate stimulate protein tyrosine phosphorylation in intact cells.
Topics: Animals; Cell Line; Humans; Hydrogen Peroxide; Immunoblotting; Insulin; Kinetics; Phosphoprotein Phosphatases; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Tumor Cells, Cultured; Tyrosine; Vanadates | 1990 |
Signal transduction of the human granulocyte-macrophage colony-stimulating factor and interleukin-3 receptors involves tyrosine phosphorylation of a common set of cytoplasmic proteins.
Topics: Antibodies, Monoclonal; Bone Marrow; Cell Division; Cell Line; Colony-Stimulating Factors; Dose-Response Relationship, Drug; Granulocyte-Macrophage Colony-Stimulating Factor; Growth Substances; Humans; Immunoblotting; Interleukin-3; Leukemia, Megakaryoblastic, Acute; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Cell Surface; Receptors, Colony-Stimulating Factor; Receptors, Immunologic; Receptors, Interleukin-3; Signal Transduction; Time Factors; Tyrosine; Vanadates | 1990 |
Protein-tyrosine phosphorylation and aggregation of intact human platelets by vanadate with H2O2.
Topics: Blood Platelets; Drug Synergism; Humans; Hydrogen Peroxide; In Vitro Techniques; Phosphorylation; Platelet Aggregation; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 1990 |
Demonstration of separate phosphotyrosyl- and phosphoseryl- histone phosphatase activities in the plasma membranes of a human astrocytoma.
Topics: 4-Nitrophenylphosphatase; Astrocytoma; Cell Line; Cell Membrane; Chromatography, Affinity; Chromatography, Gel; Chromatography, Ion Exchange; Diphosphates; Histones; Humans; Hydrolysis; In Vitro Techniques; Nitrophenols; Nucleotides; Organophosphorus Compounds; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Tissue Distribution; Tyrosine; Vanadates; Vanadium | 1985 |
Transformation of cells by an inhibitor of phosphatases acting on phosphotyrosine in proteins.
Topics: Animals; Cell Count; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cells, Cultured; Deoxyglucose; Kinetics; Mice; Moloney murine sarcoma virus; Phosphatidylinositols; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphotyrosine; Rats; Tyrosine; Vanadates; Vanadium; Zinc | 1985 |
Activation of the pp60c-src kinase by middle T antigen binding or by dephosphorylation.
Topics: Animals; Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Cell Transformation, Viral; Enzyme Activation; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Proto-Oncogene Proteins pp60(c-src); Rats; Tyrosine; Vanadates; Vanadium; Viral Proteins | 1985 |
Characterization of the phosphotyrosyl protein phosphatase activity of calmodulin-dependent protein phosphatase.
Topics: Amino Acid Sequence; Animals; Brain; Calmodulin; Cattle; Fluorides; Kinetics; Manganese; Myocardium; Myosins; Nickel; Phosphoprotein Phosphatases; Phosphoric Monoester Hydrolases; Phosphoserine; Phosphotyrosine; Protein Tyrosine Phosphatases; Serine; Tyrosine; Vanadates; Vanadium; Zinc | 1986 |
gp140v-fms molecules expressed at the surface of cells transformed by the McDonough strain of feline sarcoma virus are phosphorylated in tyrosine and serine.
Topics: Animals; Cats; Cell Transformation, Neoplastic; Genes; Genes, Viral; Oncogene Protein gp140(v-fms); Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Kinase C; Retroviridae; Retroviridae Proteins; Serine; Tyrosine; Vanadates; Vanadium | 1986 |
In vivo effect of sodium orthovanadate on pp60c-src kinase.
Topics: Amino Acid Sequence; Animals; Cells, Cultured; Chick Embryo; Fibroblasts; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins pp60(c-src); Serine; Tyrosine; Vanadates; Vanadium | 1987 |
Vanadate stimulation of phosphotyrosine protein levels in quiescent Nakano mouse lens cells.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Lens, Crystalline; Mice; Mice, Inbred Strains; Phosphoprotein Phosphatases; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Subcellular Fractions; Time Factors; Tyrosine; Vanadates; Vanadium | 1987 |
Analysis of pp60c-src tyrosine kinase activity and phosphotyrosyl phosphatase activity in human colon carcinoma and normal human colon mucosal cells.
Topics: Adenocarcinoma; Buffers; Cells, Cultured; Colonic Neoplasms; Humans; Immunologic Techniques; Intestinal Mucosa; Oncogene Protein pp60(v-src); Peptide Mapping; Phosphoprotein Phosphatases; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Retroviridae Proteins; Tyrosine; Vanadates | 1987 |
Induction of angiogenesis in vitro by vanadate, an inhibitor of phosphotyrosine phosphatases.
Topics: Animals; Cells, Cultured; Collagen; Endothelium, Vascular; Microscopy, Electron; Microscopy, Phase-Contrast; Neovascularization, Pathologic; Nucleic Acid Hybridization; Phenotype; Phosphoprotein Phosphatases; Phosphorylation; Plasminogen Activators; Protein Tyrosine Phosphatases; RNA, Messenger; Transcription, Genetic; Tyrosine; Vanadates | 1988 |
Vanadate-treated baby hamster kidney fibroblasts show cytoskeleton and adhesion patterns similar to their Rous sarcoma virus-transformed counterparts.
Topics: Actin Cytoskeleton; Animals; Avian Sarcoma Viruses; Cell Line; Cell Line, Transformed; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cricetinae; Cytoskeleton; Fibroblasts; Kidney; Phenotype; Phosphoproteins; Phosphotyrosine; Tyrosine; Vanadates | 1988 |
Effect of vanadate on the cellular accumulation of pp15, an apparent product of insulin receptor tyrosine kinase action.
Topics: Adenosine Triphosphate; Adipose Tissue; Arsenicals; Cell Line; Deoxyglucose; Drug Interactions; Electrophoresis, Polyacrylamide Gel; Insulin; Kinetics; Phosphoproteins; Phosphoserine; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Trypsin; Tyrosine; Vanadates | 1988 |
The insulin-like effect of vanadate on lipolysis in rat adipocytes is not accompanied by an insulin-like effect on tyrosine phosphorylation.
Topics: Adipose Tissue; Animals; Immunoblotting; Insulin; Isoproterenol; Lipolysis; Male; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine; Vanadates | 1989 |
Phosphorylation of the insulin receptor in permeabilized adipocytes is coupled to a rapid dephosphorylation reaction.
Topics: Adipose Tissue; Animals; Cell Membrane; Digitonin; Insulin; Kinetics; Male; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Rats; Rats, Inbred Strains; Receptor, Insulin; Tyrosine; Vanadates | 1989 |
Heparin-binding growth factor 1 stimulates tyrosine phosphorylation in NIH 3T3 cells.
Topics: Animals; Cell Line; Fibroblast Growth Factor 1; Growth Substances; Heparin; Kinetics; Molecular Weight; Phosphorylation; Proteins; Receptors, Mitogen; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Temperature; Tyrosine; Vanadates | 1989 |
Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis.
Topics: Animals; CDC2 Protein Kinase; Cell Cycle; Enzyme Activation; Mice; Mitosis; Molecular Weight; Phosphoproteins; Phosphotyrosine; Protamine Kinase; Structure-Activity Relationship; Time Factors; Tyrosine; Vanadates | 1989 |
Role of protein tyrosine phosphorylation in the NGF response.
Topics: Actin Cytoskeleton; Animals; Carbazoles; Cell Differentiation; Electrophoresis, Polyacrylamide Gel; Immunoblotting; Indole Alkaloids; Insulin; Microscopy, Fluorescence; Microtubules; Nerve Growth Factors; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Vanadates | 1989 |
Identification of proteins cross-reactive to phosphotyrosine antibodies and of a tyrosine kinase activity in boar spermatozoa.
Topics: Amino Acid Sequence; Animals; Antibodies; Blotting, Western; Calcimycin; Cross Reactions; Male; Molecular Sequence Data; Octoxynol; Oligopeptides; Phosphorylation; Phosphotyrosine; Polyethylene Glycols; Protein-Tyrosine Kinases; Solubility; Spermatozoa; Swine; Tyrosine; Vanadates | 1989 |
Phosphorylation of middle T by pp60c-src: a switch for binding of phosphatidylinositol 3-kinase and optimal tumorigenesis.
Topics: Amino Acid Sequence; Animals; Antigens, Polyomavirus Transforming; Binding Sites; Cell Transformation, Neoplastic; Cell Transformation, Viral; Enzyme Activation; Mice; Mice, Inbred C3H; Oncogene Protein pp60(v-src); Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases; Tumor Virus Infections; Tyrosine; Vanadates | 1989 |
TPCK and quercetin act synergistically with vanadate to increase protein-tyrosine phosphorylation in avian cells.
Topics: Amino Acid Chloromethyl Ketones; Animals; Avian Sarcoma Viruses; Chick Embryo; Drug Synergism; Flavonoids; Oncogene Protein pp60(v-src); Phloretin; Phosphorylation; Proteins; Quercetin; Serine Proteinase Inhibitors; Tosylphenylalanyl Chloromethyl Ketone; Trifluoperazine; Tyrosine; Vanadates | 1989 |
Vanadate and molybdate increase tyrosine phosphorylation in a 50-kilodalton protein and stimulate secretion in electropermeabilized platelets.
Topics: Blood Platelets; Blood Proteins; Blotting, Western; Cell Membrane Permeability; Dose-Response Relationship, Drug; Electrophysiology; Kinetics; Molybdenum; Phosphoprotein Phosphatases; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinases; Serotonin; Tyrosine; Vanadates | 1989 |
Inhibition of phosphotyrosine phosphatases reveals candidate substrates of the PDGF receptor kinase.
Topics: Animals; Blotting, Western; Cell Line; Fibroblasts; Mice; Peptide Mapping; Phosphoprotein Phosphatases; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinases; Protein Tyrosine Phosphatases; Proteins; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; Tyrosine; Vanadates | 1989 |
Activation of human T cells is associated with tyrosine phosphorylation of several cellular proteins.
Topics: Antibody Specificity; Humans; Kinetics; Leukemia; Lymphocyte Activation; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; T-Lymphocytes; Tumor Cells, Cultured; Tyrosine; Vanadates | 1989 |
Protein kinase C promotes the phosphorylation of immunoprecipitated middle T antigen from polyoma-transformed cells.
Topics: Animals; Antigens, Polyomavirus Transforming; Antigens, Viral, Tumor; Calcimycin; Cell Transformation, Viral; Densitometry; Mice; Molecular Weight; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphorylation; Polyomavirus; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Retroviridae Proteins; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vanadates; Vanadium | 1986 |
Enzymatic activation of Fujinami sarcoma virus gag-fps transforming proteins by autophosphorylation at tyrosine.
Topics: Animals; Avian Sarcoma Viruses; Cell Line; Chick Embryo; Gene Products, gag; Genes; Genes, Viral; Peptide Fragments; Phosphopeptides; Phosphorylation; Protein-Tyrosine Kinases; Retroviridae Proteins; Temperature; Trypsin; Tyrosine; Vanadates; Vanadium | 1987 |
Numerous proteins phosphorylated on tyrosine and enhanced tyrosine kinase activities in vanadate-treated NIH 3T3 fibroblasts.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Fibroblasts; Haptens; Hemocyanins; Mice; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 1988 |
Interaction of vanadate with phenol and tyrosine: implications for the effects of vanadate on systems regulated by tyrosine phosphorylation.
Topics: Hydrogen-Ion Concentration; Kinetics; Magnetic Resonance Spectroscopy; Phenol; Phenols; Phosphorylation; Protein Processing, Post-Translational; Tyrosine; Vanadates; Vanadium | 1986 |
Properties of a membrane-bound tyrosine kinase phosphorylating the cytosolic fragment of the red cell membrane band 3 protein.
Topics: 2,3-Diphosphoglycerate; Actins; Adenosine Triphosphate; Anion Exchange Protein 1, Erythrocyte; Chromatography; Cytosol; Diphosphoglyceric Acids; Erythrocyte Membrane; Heparin; Humans; Manganese; Peptide Fragments; Phosphorylation; Polyamines; Protein-Tyrosine Kinases; Substrate Specificity; Tyrosine; Vanadates; Vanadium | 1986 |
Suppression of cyclin D1 but not cdk4 or cyclin A with induction of melanoma terminal differentiation.
Topics: Animals; Biomarkers, Tumor; Cell Cycle; Cell Differentiation; Cell Division; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Cyclins; G1 Phase; Melanocytes; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Oncogene Proteins; Proto-Oncogene Proteins; S Phase; Tyrosine; Vanadates | 1995 |
Tyrosine kinase-dependent assembly of actin plaques linking Fc epsilon R1 cross-linking to increased cell substrate adhesion in RBL-2H3 tumor mast cells.
Topics: Actins; Animals; Antigens; Cell Adhesion; Mast Cells; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Induction of tyrosine phosphorylation and T-cell activation by vanadate peroxide, an inhibitor of protein tyrosine phosphatases.
Topics: Base Sequence; Calcium; Genes, fos; Humans; Interleukin-2; Kinetics; Leukemia; Leukocyte Common Antigens; Lymphocyte Activation; Molecular Sequence Data; NF-kappa B; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Interleukin-2; RNA, Messenger; T-Lymphocytes; Transcription, Genetic; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 1994 |
Synergistic activation of tyrosine phosphorylation by o-vanadate plus calcium ionophore A23187 or aromatic 1,2-diols.
Topics: Acetylcysteine; Angiotensin II; Animals; Calcimycin; Cell Line; Cell Line, Transformed; Drug Synergism; Egtazic Acid; Enzyme Activation; Flavonoids; Flavonols; Indomethacin; Liver; Masoprocol; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quercetin; Rats; Tyrosine; Vanadates | 1994 |
Inhibition of epidermal growth factor-dependent protein tyrosine phosphorylation by phorbol myristate acetate is mediated by protein tyrosine phosphatase activity.
Topics: 3T3 Cells; Animals; Cell Line; Egtazic Acid; Epidermal Growth Factor; ErbB Receptors; Humans; Mice; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Sodium Fluoride; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1994 |
Vanadate augments insulin-stimulated insulin receptor kinase activity and prolongs insulin action in rat adipocytes. Evidence for transduction of amplitude of signaling into duration of response.
Topics: Adipocytes; Animals; Dose-Response Relationship, Drug; Half-Life; Insulin; Kinetics; Lipids; Male; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction; Tyrosine; Vanadates | 1994 |
Activation of macrophage PtdIns-PLC by phorbol ester and vanadate: involvement of reactive oxygen species and tyrosine phosphorylation.
Topics: Animals; Enzyme Activation; Female; Macrophages, Peritoneal; Mice; Phorbol Esters; Phosphoinositide Phospholipase C; Phosphoric Diester Hydrolases; Phosphorylation; Phosphotyrosine; Reactive Oxygen Species; Tyrosine; Vanadates | 1994 |
Lipocortin 2 (annexin 2) is a major substrate for constitutive tyrosine kinase activity in chondrocytes.
Topics: Animals; Annexin A2; Cartilage, Articular; Cattle; Cells, Cultured; Chromatography, Affinity; Collagenases; Gene Expression; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; RNA, Messenger; Substrate Specificity; Tyrosine; Vanadates | 1994 |
Tyrosine phosphorylation of P-selectin in intact platelets and in a disulphide-linked complex with immunoprecipitated pp60c-src.
Topics: Blood Platelets; Disulfides; Humans; In Vitro Techniques; P-Selectin; Phosphorylation; Platelet Membrane Glycoproteins; Precipitin Tests; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Tyrosine; Vanadates | 1994 |
Increase of phosphotyrosine levels in mouse urine and liver during liver regeneration after partial hepatectomy.
Topics: Animals; Hepatectomy; Kinetics; Liver; Liver Regeneration; Male; Mice; Mice, Inbred Strains; Phosphotyrosine; Protein Tyrosine Phosphatases; Reference Values; Time Factors; Tyrosine; Vanadates | 1994 |
Junctional uvomorulin/E-cadherin and phosphotyrosine-modified protein content are correlated with paracellular permeability in Madin-Darby canine kidney (MDCK) epithelia.
Topics: Animals; Cadherins; Cell Line; Cell Membrane; Cell Membrane Permeability; Dogs; Electric Conductivity; Electrophysiology; Epithelium; Hydrogen Peroxide; Intercellular Junctions; Kidney; Membrane Potentials; Microscopy, Electron; Microscopy, Electron, Scanning; Phosphoproteins; Phosphotyrosine; Tyrosine; Vanadates | 1994 |
Vanadate stimulates differentiation and neurite outgrowth in rat pheochromocytoma PC12 cells and neurite extension in human neuroblastoma SH-SY5Y cells.
Topics: Adrenal Gland Neoplasms; Animals; Cell Differentiation; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fluorescent Antibody Technique; Humans; Immunoblotting; Kinetics; Molecular Weight; Nerve Growth Factors; Neurites; Neuroblastoma; Neurons; PC12 Cells; Pheochromocytoma; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Time Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Does the insulin-mimetic action of vanadate involve insulin receptor kinase?
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Insulin; Kinetics; Liver; Male; Phosphorylation; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Reference Values; Tyrosine; Vanadates; Weight Gain | 1993 |
Stimulatory effect of pervanadate on calcium signals and histamine secretion of RBL-2H3 cells.
Topics: Animals; Calcium; Catalase; Histamine Release; Hydrogen Peroxide; Inositol 1,4,5-Trisphosphate; Leukemia, Basophilic, Acute; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
UV radiation induces DNA fragmentation and cell death in B16 melanoma sensitized by bromodeoxyuridine: impaired c-jun induction and defective tyrosine phosphorylation signalling.
Topics: Animals; Bromodeoxyuridine; Cell Death; Cell Survival; DNA Damage; DNA, Neoplasm; Ethers, Cyclic; Genes, jun; Immunoblotting; Melanoma, Experimental; Mice; Okadaic Acid; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-jun; Radiation-Sensitizing Agents; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Ultraviolet Rays; Vanadates | 1994 |
Transforming growth factor beta down-regulates Src family protein tyrosine kinase signaling pathways.
Topics: Blotting, Western; Cell Line; Humans; Male; Oncogene Protein pp60(v-src); Oncogene Proteins, Viral; Phosphoproteins; Phosphotyrosine; Prostatic Neoplasms; Protein-Tyrosine Kinases; Receptors, Transforming Growth Factor beta; Signal Transduction; src-Family Kinases; Transforming Growth Factor beta; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Regulation of vascular and gastric smooth muscle contractility by pervanadate.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blotting, Western; Calcium; Epidermal Growth Factor; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Sodium; Stomach; Tyrosine; Vanadates | 1994 |
Effect of epidermal growth factor on cadherin-mediated adhesion in a human oesophageal cancer cell line.
Topics: alpha Catenin; Benzoquinones; beta Catenin; Cadherins; Carcinoma, Squamous Cell; Cell Adhesion; Cell Aggregation; Cell Line; Culture Techniques; Cytoskeletal Proteins; Epidermal Growth Factor; ErbB Receptors; Esophageal Neoplasms; Fibroblasts; Fluorescent Antibody Technique; Gels; Humans; Lactams, Macrocyclic; Neoplasm Invasiveness; Neoplasm Proteins; Phenotype; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Quinones; Rifabutin; Signal Transduction; Trans-Activators; Tumor Cells, Cultured; Tumor Stem Cell Assay; Tyrosine; Vanadates | 1995 |
Tyrosine phosphorylation pathway is involved in interferon-gamma (IFN-gamma) production; effect of sodium ortho vanadate.
Topics: Cell Division; HLA-DR Antigens; Humans; In Vitro Techniques; Interferon-gamma; Leukocytes, Mononuclear; Lymphocyte Activation; Phosphoproteins; Phosphotyrosine; Receptors, Interleukin-2; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Effects of chromium on basal and insulin-induced tyrosine phosphorylation in H4 hepatoma cells: comparison with phorbol-12-myristate-13-acetate and sodium orthovanadate.
Topics: Animals; Chromium; Insulin; Insulin Receptor Substrate Proteins; Liver Neoplasms, Experimental; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein Kinase C; Proteins; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Alpha 1 B, but not alpha 1A, adrenoreceptor activates calcium influx through the stimulation of a tyrosine kinase/phosphotyrosine phosphatase pathway, following noradrenaline-induced emptying of IP3 sensitive calcium stores, in PC Cl3 rat thyroid cell lin
Topics: Animals; Calcium; Cells, Cultured; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Norepinephrine; Phosphoproteins; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptors, Adrenergic, alpha; Signal Transduction; Thyroid Gland; Tyrosine; Vanadates | 1995 |
Mechanism of c-SRC activation in human melanocytes: elevated level of protein tyrosine phosphatase activity directed against the carboxy-terminal regulatory tyrosine.
Topics: Amino Acid Sequence; Biological Assay; Cell Line; Fibroblasts; Humans; Melanocytes; Molecular Sequence Data; Particle Size; Peptides; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins pp60(c-src); Solubility; Tyrosine; Vanadates | 1995 |
Functional link between phosphorylation state of membrane proteins and morphological changes of human erythrocytes.
Topics: Anion Exchange Protein 1, Erythrocyte; Erythrocyte Membrane; Ethers, Cyclic; Humans; Membrane Proteins; Microscopy, Electron, Scanning; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Spectrin; Tyrosine; Vanadates | 1995 |
Inhibitory effect of tyrphostin on the replication of herpes simplex virus type 1.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Viral; Chlorocebus aethiops; DNA Replication; Herpesvirus 1, Human; Humans; Nitriles; Phenols; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Tyrosine; Tyrphostins; Vanadates; Vero Cells; Viral Proteins; Virus Replication | 1995 |
Ligand-dependent and -independent activation of the transcription factor gamma RF-1 in a cell-free system.
Topics: Adenosine Triphosphate; Antibodies; Base Sequence; Carcinoma, Squamous Cell; Cell Line; Cell-Free System; Cytosol; Humans; Interferon-gamma; Kinetics; Leukemia, Myeloid; Ligands; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Repetitive Sequences, Nucleic Acid; Skin Neoplasms; Transcription Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Evidence for a signaling role for the alpha chains of granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and IL-5 receptors: divergent signaling pathways between GM-CSF/IL-3 and IL-5.
Topics: Alkaloids; Cell Division; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Immunoblotting; Interleukin-3; Interleukin-5; Kinetics; Leukemia, Erythroblastic, Acute; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
The mitogen-activated protein kinase cascade in rat islets of Langerhans.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Ethers, Cyclic; Glucose; Islets of Langerhans; Isoenzymes; Mitogen-Activated Protein Kinase 1; Okadaic Acid; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
Adhesion-inducible DNA synthesis regulated by tyrosine phosphorylation/dephosphorylation.
Topics: Animals; Benzoquinones; Cell Adhesion; Cell Line; DNA; Enzyme Inhibitors; Epithelium; Fibronectins; Lactams, Macrocyclic; Liver; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Signal Transduction; Tyrosine; Vanadates | 1995 |
Immobilization of nicotinic acetylcholine receptors in mouse C2 myotubes by agrin-induced protein tyrosine phosphorylation.
Topics: Agrin; Animals; Cell Line; Fluorescence; Mice; Muscle, Skeletal; Phosphorylation; Rats; Receptor Aggregation; Receptors, Nicotinic; Tyrosine; Vanadates | 1995 |
Regulation of apoptosis of interleukin 2-dependent mouse T-cell line by protein tyrosine phosphorylation and polyamines.
Topics: Animals; Apoptosis; Benzoquinones; Cell Division; Cell Line; Chromatin; DNA; Enzyme Inhibitors; Interleukin-2; Lactams, Macrocyclic; Mice; Ornithine Decarboxylase; Phosphorylation; Polyamines; Propidium; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Signal Transduction; T-Lymphocytes; Tyrosine; Vanadates | 1995 |
Combination of insulinomimetic agents H2O2 and vanadate enhances insulin receptor mediated tyrosine phosphorylation of IRS-1 leading to IRS-1 association with the phosphatidylinositol 3-kinase.
Topics: Animals; CHO Cells; Cricetinae; Hydrogen Peroxide; Insulin; Insulin Receptor Substrate Proteins; Mutation; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Tyrosine Phosphatases; Receptor, Insulin; Tyrosine; Vanadates | 1995 |
Cross-linking of CD45 on NK cells stimulates p56lck-mediated tyrosine phosphorylation and IFN-gamma production.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Cytotoxicity, Immunologic; Enzyme Activation; Enzyme Inhibitors; Genistein; Interferon-gamma; Isoflavones; Killer Cells, Natural; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphorylation; Receptors, IgG; src-Family Kinases; Tyrosine; Vanadates | 1995 |
Characterization of a Stat-like DNA binding activity in Drosophila melanogaster.
Topics: Animals; Base Sequence; Blotting, Southern; DNA-Binding Proteins; Drosophila melanogaster; Humans; Molecular Sequence Data; Phosphorylation; Promoter Regions, Genetic; Trans-Activators; Tyrosine; Vanadates | 1995 |
IL-1 beta regulates rat mesangial cyclooxygenase II gene expression by tyrosine phosphorylation.
Topics: Animals; Benzoquinones; Cells, Cultured; Dinoprostone; Gene Expression Regulation, Enzymologic; Genistein; Glomerular Mesangium; Interleukin-1; Isoflavones; Lactams, Macrocyclic; Male; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein-Tyrosine Kinases; Quinones; Rats; Rats, Sprague-Dawley; Rifabutin; RNA, Messenger; Tyrosine; Vanadates | 1995 |
Influence of protein tyrosine phosphorylation on the expression of the c-myc oncogene in cancer of the large bowel.
Topics: Benzoquinones; Cell Count; Cell Line; Colonic Neoplasms; Cycloheximide; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, myc; Genistein; Half-Life; Humans; Isoflavones; Lactams, Macrocyclic; Novobiocin; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; RNA, Messenger; Topoisomerase II Inhibitors; Tyrosine; Vanadates | 1995 |
Exogenous phosphotyrosine modulates epidermal growth factor receptor tyrosine phosphorylation.
Topics: Breast Neoplasms; Cell Division; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Vanadates | 1993 |
Myristylation is required for Tyr-527 dephosphorylation and activation of pp60c-src in mitosis.
Topics: Animals; CDC2 Protein Kinase; Chickens; Enzyme Activation; Mitosis; Mutation; Myristic Acid; Myristic Acids; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Tyrosine; Vanadates | 1993 |
Effect of orthovanadate on tyrosine phosphorylation of P120 GTPase-activating protein in rat liver macrophages (Kupffer cells).
Topics: Animals; Cells, Cultured; GTPase-Activating Proteins; Kinetics; Kupffer Cells; Phosphorylation; Phosphotyrosine; Proteins; Rats; Subcellular Fractions; Tyrosine; Vanadates | 1993 |
Interleukin 2 regulates Raf-1 kinase activity through a tyrosine phosphorylation-dependent mechanism in a T-cell line.
Topics: Animals; Cell Line; Ethers, Cyclic; Interleukin-2; Kinetics; Mice; Okadaic Acid; Phosphates; Phosphoprotein Phosphatases; Phosphorylation; Phosphotyrosine; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; T-Lymphocytes, Cytotoxic; Tyrosine; Vanadates | 1993 |
Orthovanadate induces translocation of phospholipase C-gamma 1 and -gamma 2 in permeabilized mast cells.
Topics: Animals; Cell Compartmentation; Cell Membrane Permeability; Enzyme Activation; In Vitro Techniques; Isoenzymes; Mast Cells; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Receptor Aggregation; Receptors, IgE; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 1993 |
Identification and characterization of a high-affinity interaction between v-Crk and tyrosine-phosphorylated paxillin in CT10-transformed fibroblasts.
Topics: Amino Acid Sequence; Animals; Avian Sarcoma Viruses; Blotting, Western; Cell Transformation, Viral; Cells, Cultured; Chick Embryo; Cytoskeletal Proteins; In Vitro Techniques; Molecular Sequence Data; Oligopeptides; Oncogene Protein v-crk; Oncogenes; Paxillin; Phosphoproteins; Phosphotyrosine; Protein Binding; Recombinant Fusion Proteins; Retroviridae Proteins, Oncogenic; Tyrosine; Vanadates | 1993 |
Vanadate-induced contraction of smooth muscle and enhanced protein tyrosine phosphorylation.
Topics: Animals; Calcium; Genistein; Guinea Pigs; Intestine, Large; Isoflavones; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Myosins; Peptides; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 1993 |
Identification and pKa determination of the histidine residues of human low-molecular-weight phosphotyrosyl protein phosphatases: a convenient approach using an MLEV-17 spectral editing scheme.
Topics: Amino Acid Sequence; Base Sequence; Histidine; Humans; Hydrogen; Kinetics; Magnetic Resonance Spectroscopy; Molecular Sequence Data; Molecular Weight; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Phosphotyrosine; Protein Structure, Secondary; Protein Tyrosine Phosphatases; Recombinant Proteins; Tyrosine; Vanadates | 1993 |
Cross-talk between adenylate cyclase activation and tyrosine phosphorylation leads to modulation of the actin cytoskeleton and to acute progesterone secretion in ovarian granulosa cells.
Topics: Actins; Adenylyl Cyclases; Animals; Cells, Cultured; Chorionic Gonadotropin; Colforsin; Cytoskeleton; Enzyme Activation; Female; Follicle Stimulating Hormone; Granulosa Cells; Hydrogen Peroxide; Microscopy, Electron; Phosphorylation; Phosphotyrosine; Progesterone; Rats; Tyrosine; Vanadates | 1993 |
Protein tyrosine phosphorylation is involved in osmoregulation of ionic conductances.
Topics: Benzoquinones; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Genistein; Humans; Hypotonic Solutions; Intestines; Iodides; Isoflavones; Kinetics; Lactams, Macrocyclic; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Rubidium; Tyrosine; Vanadates; Water-Electrolyte Balance | 1993 |
Tyrosine phosphorylation of a mitogen-activated protein kinase-like protein occurs at a late step in exocytosis. Studies with tyrosine phosphatase inhibitors and various secretagogues in rat RBL-2H3 cells.
Topics: Actins; Animals; Arachidonic Acid; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Electrophoresis, Polyacrylamide Gel; Exocytosis; Hexosaminidases; Hydrogen Peroxide; Inositol Phosphates; Kinetics; Leukemia, Basophilic, Acute; Phospholipids; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Tumor Cells, Cultured; Tyrosine; Vanadates | 1993 |
Dephosphorylation on tyrosine of epidermal growth factor receptor is inhibited by Ca2+ pretreatment in isolated liver membrane.
Topics: Adenosine Triphosphate; Animals; Cadaverine; Calcium; Cell Membrane; ErbB Receptors; Immunoblotting; Kinetics; Liver; Phosphorylation; Phosphotyrosine; Tyrosine; Vanadates | 1993 |
Reactive oxygen species mediate phorbol ester-regulated tyrosine phosphorylation and phospholipase A2 activation: potentiation by vanadate.
Topics: Animals; Drug Synergism; Enzyme Activation; Female; Hydrogen Peroxide; Mice; Mice, Inbred C57BL; Phospholipases A; Phospholipases A2; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Reactive Oxygen Species; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1993 |
Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor.
Topics: Alkaloids; Amyloid; Carbachol; Cell Line; Genistein; Humans; Isoflavones; Phosphorylation; Prion Proteins; Prions; Protein Kinase Inhibitors; Protein Precursors; Protein Tyrosine Phosphatases; Receptors, Muscarinic; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
Augmentation of adherens junction formation in mesenchymal cells by co-expression of N-CAM or short-term stimulation of tyrosine-phosphorylation.
Topics: 3T3 Cells; Animals; Cadherins; Cell Adhesion; Cell Adhesion Molecules, Neuronal; Cell Line; Chick Embryo; Chlorocebus aethiops; DNA, Complementary; Extracellular Matrix; Fluorescent Antibody Technique; Hydrogen Peroxide; Intercellular Junctions; Mice; Phosphorylation; Transfection; Tyrosine; Vanadates; Vinculin | 1994 |
Tyrosine kinase inhibition reduces the plateau phase of the calcium increase in response to progesterone in human sperm.
Topics: Biological Transport; Calcium; Calcium-Transporting ATPases; Genistein; Humans; Isoflavones; Male; Phosphorylation; Progesterone; Protein-Tyrosine Kinases; Spermatozoa; Terpenes; Thapsigargin; Tyrosine; Vanadates | 1995 |
Inhibition of tyrosine phosphorylation in the rat hepatic lectin 1 subunit of the rat asialoglycoprotein receptor prevents ATP-dependent receptor inactivation in permeabilized hepatocytes.
Topics: Adenosine Triphosphate; Animals; Asialoglycoprotein Receptor; Asialoglycoproteins; Cells, Cultured; Lectins; Liver; Male; Phosphoric Acids; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Cell Surface; Tyrosine; Vanadates | 1994 |
Activation of mesangial cells by the phosphatase inhibitor vanadate. Potential implications for diabetic nephropathy.
Topics: Calcium; Diabetic Nephropathies; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Glomerular Mesangium; Humans; Inositol Phosphates; Mitogens; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Protein Tyrosine Phosphatases; RNA, Messenger; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrosine; Vanadates | 1995 |
p72syk is activated by vanadate plus H2O2 in porcine platelets and phosphorylates GTPase activating protein on tyrosine residue(s).
Topics: Adenosine Triphosphatases; Animals; Blood Platelets; Enzyme Precursors; GTPase-Activating Proteins; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Phosphorylation; Platelet Aggregation; Protein-Tyrosine Kinases; Proteins; Signal Transduction; Swine; Syk Kinase; Tyrosine; Vanadates | 1994 |
Oncogenically activated or ligand-stimulated neu kinase stimulates neurite outgrowth in PC12 cells.
Topics: Animals; Bucladesine; Cells, Cultured; DNA, Complementary; Enzyme Activation; ErbB Receptors; Glycoproteins; Ligands; Nerve Growth Factors; Neuregulins; Neurites; PC12 Cells; Phosphorylation; Proto-Oncogene Proteins; Rats; Receptor, ErbB-2; Retroviridae; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1994 |
Integrin-dependent protein dephosphorylation on tyrosine induced by activation of the thrombin receptor in human platelets.
Topics: Amino Acid Sequence; Blood Platelets; Electrophoresis, Polyacrylamide Gel; Humans; In Vitro Techniques; Integrins; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Platelet Activation; Platelet Aggregation; Protein Tyrosine Phosphatases; Receptors, Thrombin; Thrombin; Tyrosine; Vanadates | 1994 |
Ca(2+)-independent arachidonic acid release by vascular endothelium requires protein synthesis de novo.
Topics: Aluminum Compounds; Animals; Arachidonic Acid; Calcium; Cells, Cultured; Cycloheximide; Dactinomycin; Endothelium, Vascular; Enzyme Activation; Fluorides; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Biosynthesis; Swine; Tyrosine; Vanadates | 1994 |
Neutrophil "priming" induced by orthovanadate: evidence of a role for tyrosine phosphorylation.
Topics: Calcium; Humans; In Vitro Techniques; Neutrophils; Phosphorylation; Signal Transduction; Tyrosine; Vanadates | 1994 |
Protein tyrosine phosphatase inhibitors block myeloid signal transduction through the Fc gamma RI receptor.
Topics: Amino Acid Sequence; Arsenicals; Bone Marrow; Cells, Cultured; Humans; Microscopy, Electron; Molecular Sequence Data; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophils; Oxidation-Reduction; Oxygen Consumption; Phosphorylation; Precipitin Tests; Protein Tyrosine Phosphatases; Receptors, IgG; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Distinct protein tyrosine phosphorylation during mitogenesis induced in quiescent SV40-transformed 3T3 T cells by insulin or vanadate.
Topics: 3T3 Cells; Animals; Blotting, Western; Cell Line, Transformed; Genistein; Insulin; Isoflavones; Mice; Mitogens; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Precipitin Tests; Protein-Tyrosine Kinases; Receptor, Insulin; Simian virus 40; T-Lymphocytes; Tyrosine; Vanadates | 1994 |
Activation of mitogen activated protein (MAP) kinases by vanadate is independent of insulin receptor autophosphorylation.
Topics: Animals; CHO Cells; Cricetinae; Enzyme Activation; Humans; Mitogen-Activated Protein Kinase 1; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Receptor, Insulin; Tyrosine; Vanadates | 1994 |
Mode-switching of a voltage-gated cation channel is mediated by a protein kinase A-regulated tyrosine phosphatase.
Topics: Animals; Aplysia; Cations; Conotoxins; Cyclic AMP-Dependent Protein Kinases; Ion Channel Gating; Mollusk Venoms; Neurons; Nitrophenols; Organophosphorus Compounds; Phosphorylation; Protein Tyrosine Phosphatases; Tyrosine; Vanadates | 1993 |
Inhibitors of tyrosine phosphorylation induce apoptosis in human leukemic cell lines.
Topics: Apoptosis; Catechols; Cell Cycle; Cell Division; Flow Cytometry; Genistein; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Interleukin-3; Isoflavones; Leukemia, Megakaryoblastic, Acute; Leukemia, Promyelocytic, Acute; Nitriles; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Vanadates | 1993 |
Cytosolic [Ca2+] homeostasis and tyrosine phosphorylation of phospholipase C gamma 2 in HL60 granulocytes.
Topics: Amino Acid Sequence; Biological Transport; Calcium; Calcium-Transporting ATPases; Cytosol; Homeostasis; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Leukemia, Promyelocytic, Acute; Manganese; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Terpenes; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 1993 |
Activation of human platelets by peroxovanadate is associated with tyrosine phosphorylation of phospholipase C gamma and formation of inositol phosphates.
Topics: Enzyme Activation; Humans; In Vitro Techniques; Inositol Phosphates; Phosphorylation; Platelet Activation; Protein Kinase C; Type C Phospholipases; Tyrosine; Vanadates | 1993 |
Decreased tyrosine phosphorylation in tumour cells resistant to FCE 24517 (tallimustine).
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Distamycins; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Humans; Leukemia L1210; Mice; Neoplasm Proteins; Nitrogen Mustard Compounds; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Sensitivity and Specificity; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Protein tyrosine phosphorylation induced by epidermal growth factor and insulin-like growth factor-I in a rat clonal dental pulp-cell line.
Topics: Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Division; Cell Line; Clone Cells; Dental Pulp; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Genistein; Humans; Insulin-Like Growth Factor Binding Protein 1; Insulin-Like Growth Factor I; Isoflavones; Mice; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptor, IGF Type 1; Recombinant Proteins; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
Erythropoietin induces the tyrosine phosphorylation, nuclear translocation, and DNA binding of STAT1 and STAT5 in erythroid cells.
Topics: Animals; Base Sequence; Biological Transport; Cell Nucleus; DNA; DNA-Binding Proteins; Erythroid Precursor Cells; Erythropoietin; Kinetics; Mice; Milk Proteins; Molecular Sequence Data; Phosphorylation; STAT1 Transcription Factor; STAT5 Transcription Factor; Trans-Activators; Tyrosine; Vanadates | 1995 |
1,25-dihydroxyvitamin D3 primes acute promyelocytic cells for TPA-induced monocytic differentiation through both PKC and tyrosine phosphorylation cascades.
Topics: Alkaloids; Calcitriol; Cell Differentiation; Enzyme Inhibitors; Genistein; Humans; Indoles; Isoflavones; Leukemia, Promyelocytic, Acute; Maleimides; Monocytes; Phagocytosis; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Manipulation of B cell antigen receptor tyrosine phosphorylation using aluminum fluoride and sodium orthovanadate.
Topics: Aluminum Compounds; Animals; B-Lymphocytes; Cells, Cultured; Fluorides; Mice; Phosphorylation; Receptors, Antigen, B-Cell; Signal Transduction; Tyrosine; Vanadates | 1995 |
Human T lymphocyte activation induces tyrosine phosphorylation of alpha-tubulin and its association with the SH2 domain of the p59fyn protein tyrosine kinase.
Topics: Amino Acid Sequence; Humans; Leukemia, T-Cell; Lymphocyte Activation; Lymphoma, T-Cell; Molecular Sequence Data; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; src Homology Domains; T-Lymphocytes; Tubulin; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Association of CD45 with Lck and components of the Ras signalling pathway in pervanadate-treated mouse T-cell lines.
Topics: Animals; Cell Line; Enzyme Inhibitors; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Phosphorylation; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins p21(ras); Rats; src Homology Domains; src-Family Kinases; T-Lymphocytes; Tyrosine; Vanadates | 1996 |
Effects of some inhibitors on myogenic differentiation of avian myoblasts transformed with Rous sarcoma virus.
Topics: Animals; Antigens; Avian Sarcoma Viruses; Cell Differentiation; Cell Fusion; Cell Line, Transformed; Cell Transformation, Viral; Creatine Kinase; Enzyme Inhibitors; Muscles; Phosphorylation; Quail; Temperature; Tyrosine; Vanadates | 1995 |
Differential role of protein tyrosine phosphorylation/dephosphorylation in affinity regulation of beta 1 and beta 3 integrin in human fibroblasts.
Topics: Antibodies, Monoclonal; Antigens, CD; Arsenicals; Cell Adhesion; Enzyme Inhibitors; Fibroblasts; Humans; Integrin beta1; Integrin beta3; Integrins; Phosphorylation; Platelet Membrane Glycoproteins; Tyrosine; Vanadates | 1995 |
An in-gel assay for protein tyrosine phosphatase activity: detection of widespread distribution in cells and tissues.
Topics: Adult; Animals; Chick Embryo; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Glutamine; Guanidine; Guanidines; Humans; Molecular Weight; Polymers; Precipitin Tests; Protein Denaturation; Protein Tyrosine Phosphatases; Rats; Rosaniline Dyes; Sodium Dodecyl Sulfate; Tyrosine; Vanadates; Yersinia | 1995 |
Coupling between [arginine8]-vasopressin-activated increases in protein tyrosine phosphorylation and cellular calcium in A7r5 aortic smooth muscle cells.
Topics: Animals; Arginine Vasopressin; Calcium; Cell Line; Enzyme Inhibitors; Extracellular Space; Genistein; Intracellular Fluid; Ion Transport; Isoflavones; Muscle, Smooth, Vascular; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Rats; Tyrosine; Vanadates | 1996 |
Potentiation of sodium butyrate-induced apoptosis by vanadate in human promyelocytic leukemia cell line HL-60.
Topics: Apoptosis; Butyrates; Butyric Acid; Cell Division; Drug Synergism; HL-60 Cells; Humans; Phosphoproteins; Phosphorylation; Tyrosine; Vanadates | 1996 |
Tyrosine phosphorylation in inflammatory neutrophils.
Topics: Arthritis, Rheumatoid; Blotting, Western; Enzyme Inhibitors; Humans; Kinetics; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Oxidoreductases; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Reference Values; Substance P; Synovial Fluid; Tyrosine; Vanadates | 1996 |
Pervanadate mediated an increased generation of inositol phosphates and tension in rat myometrium. Activation and phosphorylation of phospholipase C-gamma 1.
Topics: Animals; Blotting, Western; Enzyme Inhibitors; Female; Genistein; Inositol Phosphates; Isoenzymes; Isoflavones; Myometrium; Nitriles; Phenols; Phospholipase C gamma; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Type C Phospholipases; Tyrosine; Tyrphostins; Uterine Contraction; Vanadates | 1996 |
Vanadate causes synthesis of endothelium-derived NO via pertussis toxin-sensitive G protein in pigs.
Topics: Animals; Arginine; Blood Vessels; Bradykinin; Cinnamates; Endothelium, Vascular; Genistein; GTP-Binding Proteins; Immunoblotting; Isoflavones; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pertussis Toxin; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Sulfides; Swine; Tyrosine; Vanadates; Vasodilation; Virulence Factors, Bordetella | 1996 |
Protein tyrosine phosphorylation and the regulation of KCl cotransport in trout erythrocytes.
Topics: Animals; Carrier Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Erythrocytes; Genistein; Isoflavones; Isoproterenol; K Cl- Cotransporters; Marine Toxins; Oncorhynchus mykiss; Oxazoles; Phosphorylation; Potassium Chloride; Protein-Tyrosine Kinases; Staurosporine; Symporters; Tyrosine; Vanadates | 1996 |
Tyrosine phosphorylation of the Kv1.3 potassium channel.
Topics: Animals; Cattle; Cell Line; ErbB Receptors; Humans; Mutation; Patch-Clamp Techniques; Phosphorylation; Phosphotransferases; Potassium Channel Blockers; Potassium Channels; Protein Tyrosine Phosphatases; Transfection; Tyrosine; Vanadates | 1996 |
Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha.
Topics: Alkaloids; Base Sequence; Calcimycin; Cell Hypoxia; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Genistein; Humans; I-kappa B Proteins; Ionophores; Isoflavones; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Binding; Protein Kinase C; Protein Tyrosine Phosphatases; src-Family Kinases; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Regulation of tyrosine phosphorylation and protein tyrosine phosphatases during oligodendrocyte differentiation.
Topics: Animals; Cell Differentiation; Cytosol; Nerve Tissue Proteins; Oligodendroglia; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 5; Subcellular Fractions; Tyrosine; Vanadates | 1996 |
Effects of mitogens on androgen receptor-mediated transactivation.
Topics: Animals; Cell Line; COS Cells; Enzyme Inhibitors; Epidermal Growth Factor; Genistein; HeLa Cells; Insulin-Like Growth Factor I; Intracellular Membranes; Isoflavones; Ligands; Mitogens; Phosphorylation; Phosphotyrosine; Rats; Receptors, Androgen; Signal Transduction; Transcriptional Activation; Tyrosine; Vanadates | 1996 |
Pervanadate activation of intracellular kinases leads to tyrosine phosphorylation and shedding of syndecan-1.
Topics: Animals; Cell Line; Electrophoresis, Polyacrylamide Gel; Hydrogen Peroxide; Membrane Glycoproteins; Mice; Phosphorylation; Protein Kinases; Protein Tyrosine Phosphatases; Proteoglycans; Syndecan-1; Syndecans; Transfection; Tyrosine; Vanadates | 1996 |
Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1.
Topics: Animals; Aorta; Cattle; Caveolin 1; Caveolins; Cells, Cultured; Endothelium, Vascular; Hydrogen Peroxide; Kinetics; Membrane Proteins; Microcirculation; Nitric Oxide Synthase; Phosphates; Phosphorylation; Phosphotyrosine; Protein Binding; Pulmonary Circulation; Tyrosine; Vanadates | 1996 |
Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. Studies on murine Y1 adrenal cells.
Topics: Actins; Adrenal Cortex Neoplasms; Animals; Cell Adhesion Molecules; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Cytoskeleton; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Isoflavones; Mice; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 1996 |
Activation-independent nuclear translocation of mitogen activated protein kinase ERK1 mediated by thiol-modifying chemicals.
Topics: Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Nucleus; Enzyme Activation; Ethylmaleimide; Fluorescent Antibody Technique, Indirect; Microtubules; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein Tyrosine Phosphatases; Rats; S Phase; Sulfhydryl Reagents; Tubulin; Tyrosine; Vanadates | 1996 |
Site-specific tyrosine phosphorylation of IkappaBalpha negatively regulates its inducible phosphorylation and degradation.
Topics: Amino Acid Sequence; Blotting, Western; DNA-Binding Proteins; Enzyme Induction; Enzyme Inhibitors; HeLa Cells; Humans; I-kappa B Proteins; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Tyrosine Phosphatases; Structure-Activity Relationship; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
cAMP counter-regulates insulin-mediated protein phosphatase-2A inactivation in rat skeletal muscle cells.
Topics: Androstadienes; Animals; Cells, Cultured; Cyclic AMP; Enzyme Inhibitors; Immunosuppressive Agents; Insulin; Kinetics; Muscle, Skeletal; Phosphoprotein Phosphatases; Phosphorylation; Polyenes; Protein Phosphatase 2; Rats; Sirolimus; Tyrosine; Vanadates; Wortmannin | 1996 |
Translocation of phospholipase C-gamma 2 induced by in vitro activation of protein tyrosine kinase activity in mast cell lysates.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cations, Divalent; Cell Membrane; Enzyme Activation; Enzyme Inhibitors; Genistein; Isoenzymes; Isoflavones; Leukemia, Basophilic, Acute; Magnesium; Manganese; Mast Cells; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Rats; Sonication; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 1996 |
Tyrosine phosphorylation and translocation of phospholipase C-gamma 2 in polymorphonuclear leukocytes treated with pervanadate.
Topics: Animals; Biological Transport; Cell Membrane; Cytosol; Female; Guinea Pigs; Isoenzymes; Monocytes; Phospholipase C gamma; Phosphorylation; Superoxides; Type C Phospholipases; Tyrosine; Vanadates | 1996 |
Formation of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitors.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Enzyme Inhibitors; Golgi Apparatus; GTP-Binding Proteins; Humans; Membrane Proteins; Molecular Sequence Data; Nitriles; Phosphorylation; Phosphotyrosine; Pituitary Gland; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Tyrosine; Tyrphostins; Vanadates; Zinc | 1996 |
Peroxovanadate induces tyrosine phosphorylation of multiple signaling proteins in mouse liver and kidney.
Topics: Animals; DNA-Binding Proteins; Enzyme Inhibitors; Epidermal Growth Factor; Injections, Intraperitoneal; Kidney; Liver; Mice; Molecular Weight; Phosphorylation; Protein Sorting Signals; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; STAT1 Transcription Factor; Trans-Activators; Tyrosine; Vanadates | 1997 |
Association of Tyr phosphorylation of GTPase-activating protein with mitogenic action of serotonin.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cattle; Cell Division; Cells, Cultured; DNA; Enzyme Inhibitors; GTPase-Activating Proteins; Mitogens; Muscle, Smooth, Vascular; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Proteins; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Receptor Agonists; Tyrosine; Vanadates | 1997 |
Association of biliary glycoprotein with protein tyrosine phosphatase SHP-1 in malignant colon epithelial cells.
Topics: Amino Acid Sequence; Animals; Carcinoembryonic Antigen; Cell Adhesion Molecules; Colonic Neoplasms; Glycoproteins; Intracellular Signaling Peptides and Proteins; Mice; Molecular Sequence Data; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Tumor Cells, Cultured; Tyrosine; Vanadates | 1997 |
Differential pre- and postsynaptic modulation of chemical transmission in the squid giant synapse by tyrosine phosphorylation.
Topics: Animals; Calcium; Decapodiformes; Enzyme Inhibitors; Genistein; Isoflavones; Membrane Potentials; Microinjections; Patch-Clamp Techniques; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Stellate Ganglion; Synapses; Synaptic Transmission; Tyrosine; Vanadates | 1997 |
A role for tyrosine phosphorylation in generation of inositol phosphates and prostacyclin production in endothelial cells.
Topics: Arachidonic Acid; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Histamine; Humans; Inositol Phosphates; Isoenzymes; Phosphorylation; Protein Kinase Inhibitors; Thrombin; Type C Phospholipases; Tyrosine; Vanadates | 1997 |
Cyclic changes in the organization of cell adhesions and the associated cytoskeleton, induced by stimulation of tyrosine phosphorylation in bovine aortic endothelial cells.
Topics: Animals; Aorta; Cattle; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Epidermal Growth Factor; Fluorescent Antibody Technique, Indirect; Intercellular Junctions; Microscopy, Fluorescence; Phosphorylation; Tyrosine; Vanadates | 1997 |
Fluoride at mitogenic doses induces a sustained activation of p44mapk, but not p42mapk, in human TE85 osteosarcoma cells.
Topics: Bone and Bones; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Dose-Response Relationship, Drug; Enzyme Activation; Fibroblasts; Fluorides; Homeostasis; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Mitogens; Phosphorylation; Protein-Tyrosine Kinases; Skin; Thymidine; Tumor Cells, Cultured; Tyrosine; Vanadates | 1997 |
Interaction of the adaptor protein Shc and the adhesion molecule cadherin.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Animals; Cadherins; Cell Adhesion; Cell Size; Enzyme Inhibitors; Epidermal Growth Factor; Genetic Techniques; Mice; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatases; Proteins; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Tyrosine; Vanadates | 1997 |
Myogenin expression is necessary for commitment to differentiation and is closely related to src tyrosine kinase activity in quail myoblasts transformed with Rous sarcoma virus.
Topics: Animals; Avian Sarcoma Viruses; Benzoquinones; Cell Differentiation; Cell Transformation, Viral; Clone Cells; Enzyme Inhibitors; Gene Expression; Lactams, Macrocyclic; Muscles; Myogenin; Phosphorylation; Protein Tyrosine Phosphatases; Quail; Quinones; Rifabutin; src-Family Kinases; Tyrosine; Vanadates | 1997 |
The role of tyrosine phosphorylation in lipopolysaccharide- and zymosan-induced procoagulant activity and tissue factor expression in macrophages.
Topics: Animals; Blood Coagulation Factors; Enzyme Activation; Female; Lipopolysaccharides; Macrophages; Mice; Phosphorylation; Protein Kinase C; Thromboplastin; Tyrosine; Vanadates; Zymosan | 1997 |
Stimulation of interleukin-8 production by okadaic acid and vanadate in a human promyelocyte cell line, an HL-60 subline. Possible role of mitogen-activated protein kinase on the okadaic acid-induced NF-kappaB activation.
Topics: Base Sequence; Calcium-Calmodulin-Dependent Protein Kinases; DNA; HL-60 Cells; Humans; Hydrolysis; Interleukin-8; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Molecular Sequence Data; NF-kappa B; Okadaic Acid; Phosphorylation; RNA, Messenger; Tyrosine; Vanadates | 1997 |
Modulation of protein tyrosine phosphorylation by the extracellular matrix.
Topics: 3T3 Cells; Animals; Drug Combinations; Extracellular Matrix; Fibrin; Fibronectins; Mice; Phosphorylation; Rats; Tyrosine; Vanadates | 1997 |
Evidence that tyrosine phosphorylation regulates N-cadherin turnover during retinal development.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Brain; Cadherins; Chick Embryo; Enzyme Inhibitors; Heart; Hydrogen Peroxide; Isoquinolines; Lens, Crystalline; Myocardium; Organ Culture Techniques; Peptide Mapping; Phosphorylation; Phosphoserine; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Retina; Sulfonamides; Tyrosine; Vanadates | 1997 |
Inhibition of protein tyrosine phosphatases causes phosphorylation of tyrosine-331 in the p60 TNF receptor and inactivates the receptor-associated kinase.
Topics: Amino Acid Sequence; Antigens, CD; Binding Sites; Cytoplasm; Enzyme Activation; Enzyme Inhibitors; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Okadaic Acid; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins pp60(c-src); Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine; Vanadates | 1997 |
Human phospholipase D1 can be tyrosine-phosphorylated in HL-60 granulocytes.
Topics: Amino Acid Sequence; HL-60 Cells; Humans; Molecular Sequence Data; Molecular Weight; Phospholipase D; Phosphorylation; Tyrosine; Vanadates | 1997 |
Ortho-vanadate affects both the tyrosination/detyrosination state of spindle microtubules and the organization of XTH-2 spindles.
Topics: Animals; Cell Division; Cell Line; Centrosome; Dyneins; Endothelium, Vascular; Enzyme Inhibitors; Microtubules; Spindle Apparatus; Tubulin; Tyrosine; Vanadates; Xenopus | 1997 |
Differential T cell receptor-mediated signaling in naive and memory CD4 T cells.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; CD3 Complex; CD4-Positive T-Lymphocytes; Enzyme Precursors; Female; Immunologic Memory; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Peptide Fragments; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Signal Transduction; Syk Kinase; T-Lymphocyte Subsets; Tyrosine; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 1997 |
Tyrosine residue in exon 14 of the cytoplasmic domain of platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) regulates ligand binding specificity.
Topics: Alternative Splicing; Animals; Binding Sites; Blood Platelets; Cytoplasm; Exons; Ligands; Mice; Mutagenesis; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Protein Binding; Protein Structure, Tertiary; Sensitivity and Specificity; Tyrosine; Vanadates | 1997 |
Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity.
Topics: Amino Acid Sequence; Animals; Cell Line; Conserved Sequence; Enzyme Activation; Humans; Jurkat Cells; Kinetics; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphotyrosine; Point Mutation; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Recombinant Proteins; Spodoptera; src-Family Kinases; T-Lymphocytes; Transfection; Tyrosine; Vanadates | 1997 |
Peroxovanadate and insulin action in adipocytes from NIDDM patients. Evidence against a primary defect in tyrosine phosphorylation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Adrenergic beta-Agonists; Adult; Animals; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Humans; Hypoglycemic Agents; Insulin; Isoproterenol; Lipolysis; Male; Mice; Middle Aged; Phosphorylation; Receptor, Insulin; Tyrosine; Vanadates | 1997 |
Oxidant-induced disruption of intestinal epithelial barrier function: role of protein tyrosine phosphorylation.
Topics: Arsenicals; Bumetanide; Calcium; Cell Line; Cell Membrane Permeability; Electric Conductivity; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Intestinal Mucosa; Kinetics; Mannitol; Membrane Potentials; Octoxynol; Oxidants; Phosphorylation; Phosphotyrosine; Tumor Cells, Cultured; Tyrosine; Vanadates | 1997 |
Protein tyrosine phosphorylation and calcium signaling in thyroid FRTL-5 cells.
Topics: Adenosine Triphosphate; Animals; Arachidonic Acid; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; DNA; Genistein; Pertussis Toxin; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-fos; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Thapsigargin; Thyroid Gland; Tyrosine; Vanadates; Virulence Factors, Bordetella | 1998 |
The amino-terminal Src homology 2 domain of phospholipase C gamma 1 is essential for TCR-induced tyrosine phosphorylation of phospholipase C gamma 1.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Arginine; Cattle; ErbB Receptors; Glutathione Transferase; GRB2 Adaptor Protein; Humans; Isoenzymes; Jurkat Cells; Mutagenesis, Site-Directed; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Proteins; Receptor-CD3 Complex, Antigen, T-Cell; Recombinant Fusion Proteins; src Homology Domains; Type C Phospholipases; Tyrosine; Vanadates | 1998 |
Effects of modulation of tyrosine phosphorylation on brush border enzyme activity in human Caco-2 intestinal epithelial cells.
Topics: Alkaline Phosphatase; Caco-2 Cells; Catechols; Cell Differentiation; Cell Division; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Humans; Hydroquinones; Microvilli; Nitriles; Phosphorylation; Protein-Tyrosine Kinases; Second Messenger Systems; Tyrosine; Tyrphostins; Vanadates | 1998 |
Hormonal regulation of focal adhesions in bovine adrenocortical cells: induction of paxillin dephosphorylation by adrenocorticotropic hormone.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Cattle; Cell Adhesion Molecules; Cell Size; Cells, Cultured; Colforsin; CSK Tyrosine-Protein Kinase; Cyclic AMP; Cytoskeletal Proteins; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Immunohistochemistry; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; src-Family Kinases; Tyrosine; Vanadates | 1998 |
Differential tyrosine phosphorylation/activation of oncogenic proline-directed protein kinase F(A)/GSK-3alpha in well and poorly differentiated human prostate carcinoma cells.
Topics: Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Enzyme Activation; Enzyme Inhibitors; Genistein; Glycogen Synthase Kinase 3; Humans; Male; Molecular Sequence Data; Oncogenes; Phosphorylation; Prostatic Neoplasms; Tumor Cells, Cultured; Tyrosine; Vanadates | 1998 |
Tyrosine phosphorylation of selected secretory carrier membrane proteins, SCAMP1 and SCAMP3, and association with the EGF receptor.
Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cell Line; CHO Cells; Cricetinae; ErbB Receptors; Kidney; Membrane Proteins; Molecular Sequence Data; Phosphorylation; Protein Tyrosine Phosphatases; Rats; Time Factors; Tyrosine; Vanadates | 1998 |
Increased tyrosine phosphorylation of band 3 in hemoglobinopathies.
Topics: Adolescent; Adult; Anemia, Sickle Cell; Anion Exchange Protein 1, Erythrocyte; Antibodies; beta-Thalassemia; Erythrocyte Count; Erythrocytes; Hemoglobin SC Disease; Hemoglobinopathies; Humans; Immunoblotting; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Reticulocytes; Tyrosine; Vanadates | 1998 |
Tyrosine phosphorylation and proteolysis. Pervanadate-induced, metalloprotease-dependent cleavage of the ErbB-4 receptor and amphiregulin.
Topics: Amphiregulin; Animals; Arsenicals; EGF Family of Proteins; Enzyme Inhibitors; ErbB Receptors; Glycoproteins; Growth Substances; Intercellular Signaling Peptides and Proteins; Metalloendopeptidases; Mutation; Peptide Fragments; Phenylalanine; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Pyrrolidines; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-4; Receptors, Cell Surface; Thiocarbamates; Thiophenes; Tumor Cells, Cultured; Tyrosine; Vanadates | 1998 |
Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta.
Topics: Animals; Biological Transport; Gene Expression Regulation, Enzymologic; Isoenzymes; Mast Cells; Membrane Proteins; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase C-delta; Proto-Oncogene Proteins pp60(c-src); Rats; Receptors, IgE; Recombinant Proteins; src-Family Kinases; Tumor Cells, Cultured; Tyrosine; Vanadates | 1998 |
Modulation of olfactory bulb neuron potassium current by tyrosine phosphorylation.
Topics: Animals; Cell Line; Cells, Cultured; CSK Tyrosine-Protein Kinase; DNA Mutational Analysis; Electric Conductivity; Humans; Insulin; Neurons; Olfactory Bulb; Phosphorylation; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Shaw Potassium Channels; src-Family Kinases; Tyrosine; Vanadates | 1998 |
Effect of hepatocyte growth factor on assembly of zonula occludens-1 protein at the plasma membrane.
Topics: Animals; beta Catenin; Cadherins; Calcium; Cell Line; Cell Membrane; Cell Polarity; Cytoskeletal Proteins; Hepatocyte Growth Factor; Membrane Proteins; Phosphoproteins; Phosphorylation; Trans-Activators; Tyrosine; Vanadates; Zonula Occludens-1 Protein | 1998 |
Tyrosine-phosphorylation-dependent and rho-protein-mediated control of cellular phosphatidylinositol 4,5-bisphosphate levels.
Topics: ADP-Ribosylation Factors; Bacterial Proteins; Bacterial Toxins; Cell Line; Clostridioides difficile; Enzyme Activation; Genistein; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Membrane Proteins; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphorylation; rhoB GTP-Binding Protein; Tyrosine; Tyrphostins; Vanadates | 1998 |
Signal transduction in activation of human eosinophils: G protein-dependent and -independent pathways.
Topics: Asthma; Cell Degranulation; Enzyme Inhibitors; Eosinophils; Genistein; GTP-Binding Proteins; Humans; Immunoglobulin A, Secretory; In Vitro Techniques; Inositol Phosphates; Isoenzymes; Pertussis Toxin; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Type C Phospholipases; Tyrosine; Vanadates; Virulence Factors, Bordetella | 1998 |
Protein tyrosine phosphorylation in signalling pathways leading to the activation of gelatinase A: activation of gelatinase A by treatment with the protein tyrosine phosphatase inhibitor sodium orthovanadate.
Topics: Base Sequence; Benzoquinones; Cells, Cultured; DNA Primers; Enzyme Activation; Enzyme Inhibitors; Fibroblasts; Gelatinases; Humans; Lactams, Macrocyclic; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Monensin; Phosphorylation; Protein Tyrosine Phosphatases; Quinones; Reverse Transcriptase Polymerase Chain Reaction; Rifabutin; RNA, Messenger; Signal Transduction; Tissue Inhibitor of Metalloproteinase-2; Tyrosine; Vanadates | 1998 |
Reactive oxygen species signaling through regulation of protein tyrosine phosphorylation in endothelial cells.
Topics: Animals; Antioxidants; Calcium; Cattle; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Focal Adhesion Protein-Tyrosine Kinases; Mitogen-Activated Protein Kinases; Peroxides; Phospholipases; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Reactive Oxygen Species; Receptors, Growth Factor; Signal Transduction; Tyrosine; Vanadates | 1998 |
Vanadate-dependent FAK activation is accomplished by the sustained FAK Tyr-576/577 phosphorylation.
Topics: Amino Acid Substitution; Animals; Cell Adhesion Molecules; Cells, Cultured; Chick Embryo; CSK Tyrosine-Protein Kinase; Enzyme Activation; Focal Adhesion Protein-Tyrosine Kinases; Phenylalanine; Phosphorylation; Protein-Tyrosine Kinases; src-Family Kinases; Tyrosine; Vanadates | 1998 |
Involvement of tyrosine phosphorylation and protein kinase C in the activation of phospholipase D by H2O2 in Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Antigen-Antibody Complex; Benzoquinones; Catalase; Dose-Response Relationship, Drug; Enzyme Activation; Genistein; Hydrogen Peroxide; Kinetics; Lactams, Macrocyclic; Mice; Phospholipase D; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase C; Quinones; Rats; Receptors, Platelet-Derived Growth Factor; Rifabutin; Tyrosine; Vanadates | 1998 |
Developmental regulation of tyrosine phosphorylation of the NR2D NMDA glutamate receptor subunit in rat central nervous system.
Topics: Aging; Animals; Animals, Newborn; Brain; Enzyme Inhibitors; Phosphorylation; Precipitin Tests; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thalamus; Tyrosine; Vanadates | 1998 |
Disruption of insulin-like growth factor-1 signaling and down-regulation of cdc2 by SC-alphaalphadelta9, a novel small molecule antisignaling agent identified in a targeted array library.
Topics: Animals; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Cell Division; Cell Line; Cell Transformation, Viral; Down-Regulation; Enzyme Inhibitors; Female; Insulin-Like Growth Factor I; Mice; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Phosphorylation; Pregnancy; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, IGF Type 1; Signal Transduction; Structure-Activity Relationship; Tyrosine; Vanadates | 1998 |
Tyrosine unphosphorylated platelet SHP-1 is a substrate for calpain.
Topics: Blood Platelets; Calcimycin; Calcium Chloride; Calpain; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Platelet Activation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Substrate Specificity; Thrombin; Tyrosine; Vanadates | 1998 |
Tissue-specific expression of beta-catenin in normal mesenchyme and uveal melanomas and its effect on invasiveness.
Topics: 3T3 Cells; Adenomatous Polyposis Coli; Adult; Animals; beta Catenin; Cadherins; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Line; Cell Membrane; Cytoplasm; Cytoskeletal Proteins; Dogs; Epithelium; Glycogen Synthase Kinase 3; Humans; Melanoma; Mesoderm; Mice; Neoplasm Invasiveness; Phenotype; Phosphorylation; Protein Tyrosine Phosphatases; Staining and Labeling; Trans-Activators; Tumor Cells, Cultured; Tyrosine; Uveal Neoplasms; Vanadates | 1998 |
Acute suppression of inwardly rectifying Kir2.1 channels by direct tyrosine kinase phosphorylation.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Membrane; Consensus Sequence; Epidermal Growth Factor; Genistein; Insulin; Membrane Potentials; Mutagenesis, Site-Directed; Nerve Growth Factors; Oocytes; Phosphorylation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein-Tyrosine Kinases; Rats; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates; Xenopus laevis | 1998 |
Induction of the antigen receptor expression on B lymphocytes results in rapid competence for signaling of SLP-65 and Syk.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; B-Lymphocytes; Base Sequence; Biological Transport; Carrier Proteins; Cell Line; Enzyme Precursors; Gene Expression Regulation; Integrases; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Recombination, Genetic; Signal Transduction; src-Family Kinases; Syk Kinase; Tamoxifen; Transfection; Tyrosine; Vanadates; Viral Proteins | 1998 |
Role of tyrosine phosphorylation in the regulation of cerebral vascular tone in newborn pig in vivo.
Topics: Animals; Animals, Newborn; Arsenicals; Arterioles; Cerebrovascular Circulation; Enzyme Inhibitors; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Pia Mater; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Swine; Tyrosine; Vanadates; Vasodilator Agents; Vasomotor System | 1999 |
Modulation of neurotransmitter release by dihydropyridine-sensitive calcium channels involves tyrosine phosphorylation.
Topics: Adenosine Triphosphate; Animals; Aspartic Acid; Calcium; Calcium Channel Blockers; Calcium Channels; Calcium Channels, L-Type; Cell Adhesion Molecules; Cerebellum; Dihydropyridines; Electrophysiology; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Membrane Potentials; Nerve Tissue Proteins; Nifedipine; omega-Conotoxins; Peptides; Phosphorylation; Potassium; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Time Factors; Tritium; Tyrosine; Vanadates; Vinculin | 1999 |
A two-component affinity chromatography purification of Helix pomatia arylsulfatase by tyrosine vanadate.
Topics: Animals; Arylsulfatases; Chromatography, Affinity; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Helix, Snails; Isoenzymes; Tyrosine; Vanadates | 1999 |
Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells.
Topics: Breast Neoplasms; Endopeptidases; Humans; Hydroxamic Acids; Metalloendopeptidases; Phenylalanine; Phosphorylation; Protease Inhibitors; Receptor, ErbB-2; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured; Tyrosine; Vanadates | 1999 |
Rapid inactivation of NOS-I by lipopolysaccharide plus interferon-gamma-induced tyrosine phosphorylation.
Topics: Astrocytoma; Enzyme Induction; Genistein; Humans; Interferon-gamma; Lipopolysaccharides; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Phosphorylation; Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Tyrosine; Vanadates | 1999 |
Mechanisms of inhibition of lipolysis by insulin, vanadate and peroxovanadate in rat adipocytes.
Topics: Adipocytes; Animals; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Isoproterenol; Lipolysis; Male; Peptide Mapping; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Rats; Rats, Sprague-Dawley; Tyrosine; Vanadates | 1999 |
Possible regulation of epidermal growth factor-receptor tyrosine autophosphorylation by calcium and G proteins in chemically permeabilized rat UMR106 cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Carcinoma; Cell Membrane Permeability; Culture Media; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; GTP-Binding Proteins; Humans; Osteoblasts; Osteosarcoma; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Signal Transduction; Time Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 1999 |
The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Base Sequence; COS Cells; DNA Primers; Erythrocytes; Intracellular Signaling Peptides and Proteins; Mutagenesis, Site-Directed; N-Acetylneuraminic Acid; Phosphopeptides; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Sialic Acid Binding Ig-like Lectin 3; Tyrosine; Vanadates | 1999 |
Tyrosine phosphorylation/dephosphorylation controls capping of Fcgamma receptor II in U937 cells.
Topics: Arsenicals; Bacterial Proteins; Benzoquinones; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Humans; Immunoblotting; Lactams, Macrocyclic; Microscopy, Fluorescence; Okadaic Acid; Phosphorylation; Quinones; Receptor Aggregation; Receptors, IgG; Rifabutin; Streptolysins; Temperature; Time Factors; Tyrosine; U937 Cells; Vanadates | 1999 |
L-type Ca2+ current in guinea pig ventricular myocytes treated with modulators of tyrosine phosphorylation.
Topics: Animals; Cadmium; Calcium Channels; Calcium Channels, L-Type; Cells, Cultured; Electrophysiology; Enzyme Inhibitors; Estrogens, Non-Steroidal; Genistein; Guinea Pigs; Isoflavones; Membrane Potentials; Muscle Fibers, Skeletal; Myocardium; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine; Tyrphostins; Vanadates | 1999 |
Activation of STAT1 alpha by phosphatase inhibitor vanadate in glomerular mesangial cells: involvement of tyrosine and serine phosphorylation.
Topics: Animals; Cells, Cultured; DNA-Binding Proteins; Enzyme Inhibitors; Glomerular Mesangium; Phosphoric Monoester Hydrolases; Phosphorylation; Rats; Serine; Signal Transduction; STAT1 Transcription Factor; Trans-Activators; Tyrosine; Vanadates | 1999 |
Negative regulation by protein tyrosine phosphatase of IFN-gamma-dependent expression of inducible nitric oxide synthase.
Topics: Adjuvants, Immunologic; Animals; Cells, Cultured; DNA-Binding Proteins; Down-Regulation; Drug Synergism; I-kappa B Proteins; Interferon-gamma; Macrophages, Peritoneal; Male; Mice; NF-kappa B; NF-KappaB Inhibitor alpha; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Phosphorylation; Protein Tyrosine Phosphatases; Signal Transduction; Tyrosine; Vanadates | 1999 |
Pervanadate-mediated tyrosine phosphorylation of keratins 8 and 19 via a p38 mitogen-activated protein kinase-dependent pathway.
Topics: Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colon; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Keratins; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Serine; Signal Transduction; Solubility; Tyrosine; Vanadates | 1999 |
Oxidative stress triggers STAT3 tyrosine phosphorylation and nuclear translocation in human lymphocytes.
Topics: Arsenicals; Cell Nucleus; Copper; Diamide; DNA-Binding Proteins; Enzyme Inhibitors; Genistein; Humans; Hydrogen Peroxide; Iron; Lymphocytes; Oxidative Stress; Phenanthrolines; Phosphorylation; Phosphotyrosine; Phytohemagglutinins; Protein Tyrosine Phosphatases; Reactive Oxygen Species; STAT3 Transcription Factor; Trans-Activators; Tyrosine; Vanadates | 1999 |
Tyrosine phosphorylation of the proto-oncoprotein Raf-1 is regulated by Raf-1 itself and the phosphatase Cdc25A.
Topics: 3T3 Cells; Animals; cdc25 Phosphatases; Cell Line; Enzyme Activation; Enzyme Inhibitors; Janus Kinase 2; Mice; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rabbits; Spodoptera; Tyrosine; Vanadates | 1999 |
Vanadate induction of NF-kappaB involves IkappaB kinase beta and SAPK/ERK kinase 1 in macrophages.
Topics: Animals; Cell Line; Enzyme Activation; I-kappa B Kinase; Macrophages; MAP Kinase Kinase 4; Mice; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Tyrosine; Vanadates | 1999 |
Insulin-induced stimulation of Na+,K(+)-ATPase activity in kidney proximal tubule cells depends on phosphorylation of the alpha-subunit at Tyr-10.
Topics: Amino Acid Substitution; Animals; Cells, Cultured; Enzyme Activation; Genistein; Insulin; Insulin Antagonists; Kidney Tubules, Proximal; Male; Opossums; Ouabain; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Transfection; Tyrosine; Vanadates | 1999 |
Decavanadate inhibits the cell-free activation of neutrophil NADPH oxidase without affecting tyrosine phosphorylation.
Topics: Amino Acid Sequence; Animals; Biological Transport; Cell-Free System; Cells, Cultured; Enzyme Activation; Female; Guinea Pigs; Hydrogen-Ion Concentration; Kinetics; Molecular Sequence Data; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Tyrosine; Vanadates | 1999 |
Regulation of intestinal tyrosine phosphorylation and programmed cell death by peroxovanadate.
Topics: Animals; Apoptosis; Cells, Cultured; DNA Fragmentation; Ileum; Intestinal Mucosa; Male; Mice; Mice, Inbred Strains; Phosphorylation; Temperature; Time Factors; Tyrosine; Vanadates | 1999 |
Regulation of capacitative Ca2+ entry by tyrosine phosphorylation in the neural retina of chick embryo.
Topics: Animals; Calcium; Chick Embryo; Enzyme Inhibitors; Phosphorylation; Retina; Tyrosine; Vanadates | 1999 |
Differential modulation of the tyrosine phosphorylation state of the insulin receptor by IRS (insulin receptor subunit) proteins.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Motifs; Animals; Insulin; Insulin Receptor Substrate Proteins; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Proteins; Receptor, Insulin; Recombinant Proteins; Sequence Deletion; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Stem Cells; Tyrosine; Vanadates | 1999 |
Novel association of the src family kinases, hck and c-fgr, with CCR3 receptor stimulation: A possible mechanism for eotaxin-induced human eosinophil chemotaxis.
Topics: Benzoquinones; Chemokine CCL11; Chemokines, CC; Chemotaxis, Leukocyte; Cytokines; Drug Synergism; Enzyme Inhibitors; Eosinophils; Humans; Lactams, Macrocyclic; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Quinones; Receptors, CCR3; Receptors, Chemokine; Rifabutin; src-Family Kinases; Tyrosine; Vanadates | 1999 |
Annexin VII and annexin XI are tyrosine phosphorylated in peroxovanadate-treated dogs and in platelet-derived growth factor-treated rat vascular smooth muscle cells.
Topics: Amino Acid Sequence; Animals; Annexin A7; Annexins; Dogs; Kidney; Liver; Muscle, Smooth, Vascular; Phosphorylation; Platelet-Derived Growth Factor; Rats; Rats, Sprague-Dawley; Tyrosine; Vanadates | 1999 |
Independent regulation of adherens and tight junctions by tyrosine phosphorylation in Caco-2 cells.
Topics: Caco-2 Cells; Cadherins; Cell Adhesion Molecules; Cytoskeletal Proteins; Fluorescent Antibody Technique; Humans; Microscopy, Electron; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Tight Junctions; Transfection; Tyrosine; Vanadates | 1999 |
Distinct, constitutively active MAPK phosphatases function in Xenopus oocytes: implications for p42 MAPK regulation In vivo.
Topics: Animals; Enzyme Activation; Kinetics; MAP Kinase Kinase 1; Meiosis; Microinjections; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Okadaic Acid; Oocytes; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Threonine; Tyrosine; Vanadates; Xenopus | 1999 |
Tyrosine phosphorylation of caveolin-1 in the endothelium.
Topics: Animals; Aorta; Cattle; Caveolin 1; Caveolins; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; Intracellular Membranes; Membrane Proteins; Microscopy, Immunoelectron; Oxidative Stress; Phosphorylation; Rats; Tyrosine; Umbilical Veins; Vanadates | 1999 |
Involvement of the membrane distal catalytic domain in pervanadate-induced tyrosine phosphorylation of receptor protein-tyrosine phosphatase alpha.
Topics: Catalytic Domain; Cell Membrane; Enzyme Inhibitors; Humans; Mutagenesis, Site-Directed; Neuroectodermal Tumors, Primitive, Peripheral; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
Membrane cofactor protein (MCP; CD46): isoform-specific tyrosine phosphorylation.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigens, CD; Cell Line; CHO Cells; Complement Inactivator Proteins; Cricetinae; Cytoplasm; Humans; Jurkat Cells; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Membrane Cofactor Protein; Membrane Glycoproteins; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Protein Isoforms; Proto-Oncogene Proteins pp60(c-src); Substrate Specificity; Tyrosine; Vanadates | 2000 |
Tyrosine phosphorylation modulates arteriolar tone but is not fundamental to myogenic response.
Topics: Animals; Arterioles; Enzyme Inhibitors; Genistein; In Vitro Techniques; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Osmolar Concentration; Phosphoric Monoester Hydrolases; Phosphorylation; Pressure; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrphostins; Vanadates; Vasoconstriction; Vasomotor System | 2000 |
Tyrosine phosphorylation of myelin P(0) and its implication in signal transduction.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Brain; Cell Line; Cloning, Molecular; Consensus Sequence; Humans; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Myelin P0 Protein; Neurilemmoma; Phenylalanine; Phosphorylation; Phosphotyrosine; Recombinant Proteins; Sequence Alignment; Signal Transduction; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
Systematic analysis of the role of CD19 cytoplasmic tyrosines in enhancement of activation in Daudi human B cells: clustering of phospholipase C and Vav and of Grb2 and Sos with different CD19 tyrosines.
Topics: Adaptor Proteins, Signal Transducing; Adjuvants, Immunologic; Antigens, CD19; B-Lymphocytes; Calcium Signaling; Cell Cycle Proteins; Cytoplasm; Exons; GRB2 Adaptor Protein; Humans; Isoenzymes; Lymphocyte Activation; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Molecular Weight; Mutagenesis, Site-Directed; Peptide Mapping; Phospholipase C gamma; Phosphopeptides; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Receptors, Antigen, B-Cell; Son of Sevenless Protein, Drosophila; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 2000 |
Pervanadate-induced nuclear factor-kappaB activation requires tyrosine phosphorylation and degradation of IkappaBalpha. Comparison with tumor necrosis factor-alpha.
Topics: Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; HeLa Cells; Humans; I-kappa B Proteins; Leupeptins; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Proteasome Endopeptidase Complex; Protein Tyrosine Phosphatases; Transcription, Genetic; Tumor Necrosis Factor-alpha; Tyrosine; U937 Cells; Vanadates | 2000 |
Regulation of chicken protein tyrosine phosphatase 1 and human protein tyrosine phosphatase 1B activity by casein kinase II- and p56lck-mediated phosphorylation.
Topics: Adenosine Triphosphate; Animals; Casein Kinase II; Chickens; Dose-Response Relationship, Drug; Heparin; Humans; Hydrogen Peroxide; Intercellular Signaling Peptides and Proteins; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Peptides; Phosphorus Radioisotopes; Phosphorylation; Protein Phosphatase 1; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Tyrosine; Vanadates | 2000 |
Adhesion-dependent tyrosine phosphorylation of (beta)-dystroglycan regulates its interaction with utrophin.
Topics: Amino Acid Motifs; Amino Acid Sequence; Binding Sites; Cell Adhesion; Cell Membrane; Cytoskeletal Proteins; Dystroglycans; HeLa Cells; Humans; Membrane Glycoproteins; Membrane Proteins; Molecular Sequence Data; Phosphorylation; Protein Structure, Tertiary; Tyrosine; Utrophin; Vanadates | 2000 |
Tyrosine phosphorylation of a 34-kDa protein induced by cross-linking a novel glycosylphosphatidylinositol-anchored glycoprotein (GPI-80) on human neutrophils that may regulate their adherence and migration.
Topics: Amidohydrolases; Androstadienes; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Chelating Agents; Cross-Linking Reagents; Cytochalasin B; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Genistein; GPI-Linked Proteins; Humans; Hydrolases; Indoles; Mice; Mice, Inbred BALB C; Neutrophils; Pertussis Toxin; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Signal Transduction; Time Factors; Tyrosine; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2000 |
Enhancement of Ca2+-induced noradrenaline release by vanadate in PC12 cells: possible involvement of tyrosine phosphorylation.
Topics: Animals; Calcium; Intercellular Signaling Peptides and Proteins; Intracellular Membranes; Ionomycin; Ionophores; Norepinephrine; Osmolar Concentration; PC12 Cells; Peptides; Phosphorylation; Rats; Tetradecanoylphorbol Acetate; Tetramisole; Tyrosine; Vanadates; Wasp Venoms | 2000 |
Regulation of mouse podocyte process dynamics by protein tyrosine phosphatases rapid communication.
Topics: Actins; Animals; Cells, Cultured; Cytoskeleton; Epithelial Cells; Kidney Glomerulus; Mice; Phosphorylation; Protamines; Protein Tyrosine Phosphatases; Puromycin Aminonucleoside; Tyrosine; Vanadates | 2000 |
Tumor-derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate.
Topics: Actin Cytoskeleton; Actins; alpha Catenin; Animals; beta Catenin; Cadherins; Catenins; Cell Adhesion Molecules; Cell Line; Cytoskeletal Proteins; Cytoskeleton; Delta Catenin; Desmoplakins; Enzyme Inhibitors; Humans; Mice; Mutation; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Stomach Neoplasms; Trans-Activators; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
Insulin resistance in fat cells from obese Zucker rats--evidence for an impaired activation and translocation of protein kinase B and glucose transporter 4.
Topics: Adipocytes; Aging; Animals; Electrophoresis, Polyacrylamide Gel; Glucose; Glucose Transporter Type 4; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Monosaccharide Transport Proteins; Muscle Proteins; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Signal Transduction; Tyrosine; Vanadates | 2000 |
Oxidative stress and vanadate induce tyrosine phosphorylation of phosphoinositide-dependent kinase 1 (PDK1).
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Androstadienes; Cell Line; Humans; Hydrogen Peroxide; Immediate-Early Proteins; Nerve Growth Factor; Nuclear Proteins; Oxidative Stress; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tyrosine; Vanadates; Wortmannin | 2000 |
Identification of Grb10 as a direct substrate for members of the Src tyrosine kinase family.
Topics: Animals; CHO Cells; Cricetinae; GRB10 Adaptor Protein; Insulin; Mutagenesis, Site-Directed; Phosphorylation; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; src-Family Kinases; Substrate Specificity; Tyrosine; Vanadates | 2000 |
Towards models of vanadate-dependent haloperoxidases: the hydroxyl side chain.
Topics: Binding Sites; Cysteine; Homoserine; Hydroxyl Radical; Magnetic Resonance Spectroscopy; Models, Chemical; Models, Molecular; Molecular Structure; Peroxidases; Protein Tyrosine Phosphatases; Serine; Threonine; Tyrosine; Vanadates | 2000 |
The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Antigens, CD; Carrier Proteins; CD79 Antigens; Cytoplasm; Enzyme Inhibitors; Humans; Immunoglobulin Fragments; Immunoglobulin Variable Region; Molecular Sequence Data; Phosphoproteins; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Receptors, Antigen, B-Cell; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
Involvement of a p38 mitogen-activated protein kinase phosphatase in protecting neonatal rat cardiac myocytes from ischemia.
Topics: Animals; Animals, Newborn; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Ischemia; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine; Vanadates | 2000 |
Substrates of semicarbazide-sensitive amine oxidase co-operate with vanadate to stimulate tyrosine phosphorylation of insulin-receptor-substrate proteins, phosphoinositide 3-kinase activity and GLUT4 translocation in adipose cells.
Topics: 3T3 Cells; Adipocytes; Amine Oxidase (Copper-Containing); Animals; Benzylamines; Glucose Transporter Type 4; Insulin Receptor Substrate Proteins; Male; Mice; Monosaccharide Transport Proteins; Muscle Proteins; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Substrate Specificity; Tyrosine; Vanadates | 2000 |
c-Crk, a substrate of the insulin-like growth factor-1 receptor tyrosine kinase, functions as an early signal mediator in the adipocyte differentiation process.
Topics: 3T3 Cells; Adipocytes; Amino Acid Sequence; Animals; Cell Differentiation; Enzyme Inhibitors; Mice; Molecular Sequence Data; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Receptor, IGF Type 1; RNA, Antisense; Signal Transduction; src Homology Domains; Substrate Specificity; Tyrosine; Vanadates | 2000 |
Tyrosine phosphorylation and cellular redistribution of ezrin in MDCK cells treated with pervanadate.
Topics: Amino Acid Sequence; Animals; Antibodies; Cell Line; Cell Membrane; Cytoskeletal Proteins; Cytosol; Dogs; Kidney; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Tyrosine; Vanadates | 2000 |
Tyrosine phosphorylation-dependent inhibition of hippocampal synaptic plasticity.
Topics: Animals; Arsenicals; Depression, Chemical; Down-Regulation; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Potentiation; Male; Neuronal Plasticity; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Synapses; Tyrosine; Vanadates | 2000 |
Stimulation of receptor-mediated nitric oxide production by vanadate.
Topics: Animals; Carrier Proteins; Cattle; Cell Compartmentation; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Gene Expression; HSP90 Heat-Shock Proteins; Intracellular Signaling Peptides and Proteins; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Protein Tyrosine Phosphatases; Receptors, Cell Surface; Tyrosine; Vanadates | 2000 |
Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes.
Topics: Amino Acid Substitution; Antigens, CD; Antigens, Surface; Binding Sites; Cell Line; Cytoplasm; Desmosomes; Enzyme Inhibitors; Humans; Integrin alpha6; Integrin alpha6beta4; Integrin beta4; Integrins; Phenylalanine; Phosphopeptides; Phosphorylation; Phosphotyrosine; Recombinant Proteins; Signal Transduction; src Homology Domains; Transfection; Tyrosine; Vanadates | 2001 |
Endothelins increase tyrosine phosphorylation of astrocytic focal adhesion kinase and paxillin accompanied by their association with cytoskeletal components.
Topics: Androstadienes; Angiotensin II; Animals; Animals, Newborn; Astrocytes; Bradykinin; Bucladesine; Cerebral Cortex; Chelating Agents; Cytochalasin B; Cytoskeletal Proteins; Cytoskeleton; Endothelin Receptor Antagonists; Endothelin-1; Endothelin-3; Endothelins; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Paxillin; Pertussis Toxin; Phosphoproteins; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Receptors, Endothelin; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates; Virulence Factors, Bordetella; Wortmannin | 2000 |
Enhancement of nuclear factor-kappaB activation and protein tyrosine phosphorylation by a tyrosine phosphatase inhibitor, pervanadate, involves reactive oxygen species in silica-stimulated macrophages.
Topics: Animals; Blotting, Western; Cell Line; Cell Nucleus; Electrophoresis; Enzyme Inhibitors; Macrophages; Mice; NF-kappa B; Precipitin Tests; Protein Tyrosine Phosphatases; Reactive Oxygen Species; Silicon Dioxide; Stimulation, Chemical; Tyrosine; Vanadates | 2000 |
Constitutive and growth factor-regulated phosphorylation of caveolin-1 occurs at the same site (Tyr-14) in vivo: identification of a c-Src/Cav-1/Grb7 signaling cassette.
Topics: 3T3 Cells; Adipocytes; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Caveolae; Caveolin 1; Caveolins; Cell Adhesion; Cell Division; Cell Movement; Epidermal Growth Factor; ErbB Receptors; Female; GRB7 Adaptor Protein; Growth Substances; Humans; Insulin; Lipid Metabolism; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Phosphorylation; Proteins; Signal Transduction; src-Family Kinases; Tyrosine; Vanadates | 2000 |
Vanadate enhances but does not normalize glucose transport and insulin receptor phosphorylation in skeletal muscle from obese women with gestational diabetes mellitus.
Topics: Biological Transport; Diabetes, Gestational; Female; Glucose; Humans; Insulin Receptor Substrate Proteins; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Pregnancy; Pregnancy Complications; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Receptor, Insulin; Reference Values; Tyrosine; Vanadates | 2000 |
Diperoxovanadate alters endothelial cell focal contacts and barrier function: role of tyrosine phosphorylation.
Topics: Actins; Animals; Antigens, CD; Cadherins; Capillary Permeability; Cattle; Cell Adhesion Molecules; Cell Communication; Cell Line; Electric Impedance; Endothelium, Vascular; Enzyme Inhibitors; Fluorescent Antibody Technique; Mitogen-Activated Protein Kinases; Peroxides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 2000 |
Cell density regulates tyrosine phosphorylation and localization of focal adhesion kinase.
Topics: 3T3 Cells; Animals; Cell Adhesion; Cell Count; Detergents; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; HeLa Cells; Humans; Intracellular Fluid; Mice; Octoxynol; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Solubility; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation.
Topics: 3T3 Cells; Androstadienes; Animals; Cysteine Endopeptidases; Enzyme Inhibitors; Insulin; Insulin Receptor Substrate Proteins; Mice; Multienzyme Complexes; Okadaic Acid; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Protein Kinase Inhibitors; Serine; Sirolimus; Threonine; Time Factors; Tyrosine; Vanadates; Wortmannin | 2001 |
Protein tyrosine phosphatase-dependent proteolysis of focal adhesion complexes in endothelial cell apoptosis.
Topics: Adenosine; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Caspases; Cattle; Crk-Associated Substrate Protein; Cysteine Proteinase Inhibitors; Cytoskeletal Proteins; Endothelium, Vascular; Fluorescent Antibody Technique; Focal Adhesion Protein-Tyrosine Kinases; Focal Adhesions; Homocysteine; Hydrolysis; Paxillin; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; Tyrosine; Vanadates; Vinculin | 2001 |
Effects of phosphotyrosine phosphatase inhibition on insulin secretion and intracellular signaling events in rat pancreatic islets.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Glucose; Hypoglycemic Agents; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Insulin Secretion; Intracellular Signaling Peptides and Proteins; Islets of Langerhans; Male; MAP Kinase Signaling System; Pertussis Toxin; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Time Factors; Tyrosine; Vanadates; Virulence Factors, Bordetella | 2001 |
Cell-cycle dependent tyrosine phosphorylation on mortalin regulates its interaction with fibroblast growth factor-1.
Topics: 3T3 Cells; Animals; Carrier Proteins; Cell Cycle; Cell Line; DNA; Electrophoresis, Polyacrylamide Gel; Fibroblast Growth Factor 1; HSP70 Heat-Shock Proteins; Immunoblotting; Mice; Mice, Inbred BALB C; Microscopy, Fluorescence; Phosphorylation; Precipitin Tests; Protein Binding; Time Factors; Tyrosine; Vanadates | 2001 |
GSH role on platelet-derived growth factor receptor tyrosine phosphorylation induced by H2O2.
Topics: 3T3 Cells; Animals; Blotting, Western; Buthionine Sulfoximine; Dose-Response Relationship, Drug; Glutathione; Hydrogen Peroxide; Maleates; Mice; Phosphorylation; Protein Tyrosine Phosphatases; Receptors, Platelet-Derived Growth Factor; Tyrosine; Vanadates | 2001 |
FTY720, a novel immunosuppressive agent, induces apoptosis in human glioma cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Caspase 3; Caspase 6; Caspases; Cell Death; Cell Survival; Cysteine Proteinase Inhibitors; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Activation; Etoposide; Fingolimod Hydrochloride; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Glioma; Humans; Immunosuppressive Agents; Oligopeptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Propylene Glycols; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Sphingosine; Time Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
Tyrosine phosphorylation increases Ca2+ sensitivity of vascular smooth muscle contraction.
Topics: Animals; Calcium; Calcium Radioisotopes; Genistein; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth, Vascular; Norepinephrine; Phosphorylation; Potassium Chloride; Tyrosine; Vanadates; Vasoconstrictor Agents | 2000 |
Agents that increase tyrosine phosphorylation activate a non-selective cation current in single rabbit portal vein smooth muscle cells.
Topics: Animals; Artifacts; Calcium; Cations; Cytosol; Drug Synergism; Electric Conductivity; Enzyme Activation; Enzyme Inhibitors; Extracellular Space; Insulin; Ion Channels; Muscle, Smooth, Vascular; Norepinephrine; Phosphorylation; Portal Vein; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Rabbits; Receptor Protein-Tyrosine Kinases; Tyrosine; Vanadates | 2001 |
Phospholipase C-gamma mediates the hydrolysis of phosphatidylinositol, but not of phosphatidylinositol 4,5-bisphoshate, in carbamylcholine-stimulated islets of langerhans.
Topics: Adenoviridae; Androstadienes; Animals; Carbachol; Cholinergic Agonists; Chromatography, High Pressure Liquid; Chromones; Enzyme Inhibitors; Genistein; Hydrolysis; Inositol Phosphates; Islets of Langerhans; Isoenzymes; Membrane Potentials; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Rats; Signal Transduction; Time Factors; Type C Phospholipases; Tyrosine; Vanadates; Wortmannin | 2001 |
Vanadate facilitates interferon alpha-mediated apoptosis that is dependent on the Jak/Stat pathway.
Topics: Acetylcysteine; Apoptosis; Caspase 3; Caspases; Cell Line; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Immunoblotting; Interferon-alpha; Janus Kinase 1; Jurkat Cells; Mutation; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Reactive Oxygen Species; Ribonucleases; Signal Transduction; STAT1 Transcription Factor; STAT2 Transcription Factor; Time Factors; Trans-Activators; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; TYK2 Kinase; Tyrosine; Vanadates | 2001 |
Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling.
Topics: Adaptor Proteins, Signal Transducing; Animals; CD3 Complex; COS Cells; Enzyme Activation; Gene Expression Regulation, Enzymologic; GRB2 Adaptor Protein; Humans; Immunoblotting; Jurkat Cells; Kinetics; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Membrane Microdomains; Nuclear Proteins; Oncogene Proteins; Phosphorylation; Plasmids; Precipitin Tests; Proline; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Receptors, Antigen, T-Cell; Signal Transduction; Time Factors; Transfection; Tyrosine; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 2001 |
Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases.
Topics: Amino Acid Substitution; Antibodies, Monoclonal; CD3 Complex; CD5 Antigens; Enzyme Activation; Humans; Jurkat Cells; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mutation; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Recombinant Fusion Proteins; T-Lymphocytes; Transfection; Tyrosine; Vanadates | 2001 |
Tyrosine kinase-mediated serine phosphorylation of adenylyl cyclase.
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amino Acid Sequence; Animals; Blotting, Western; Catalytic Domain; Cells, Cultured; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; Humans; Intracellular Fluid; Isoenzymes; Molecular Sequence Data; Mutagenesis, Site-Directed; Phosphoamino Acids; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-raf; Rats; Serine; Staurosporine; Tyrosine; Up-Regulation; Vanadates | 2001 |
Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases.
Topics: Animals; Calcium; Carbachol; Carcinogens; Cholinergic Agents; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Estrenes; Isoenzymes; Male; Neurons; Parotid Gland; PC12 Cells; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serine; src-Family Kinases; Substance P; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vanadates | 2001 |
Identification of Src phosphorylation sites in the catenin p120ctn.
Topics: Animals; Binding Sites; Blotting, Western; Catenins; Cell Adhesion Molecules; Cell Line; COS Cells; Cytoplasm; Delta Catenin; DNA Mutational Analysis; Electrophoresis, Gel, Two-Dimensional; Epidermal Growth Factor; Gene Deletion; Genes, Dominant; Glutathione Transferase; Humans; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins pp60(c-src); Transfection; Tyrosine; Vanadates | 2001 |
Ligand stimulation reduces platelet-derived growth factor beta-receptor susceptibility to tyrosine dephosphorylation.
Topics: Agglutinins; Animals; Catalytic Domain; Cell Membrane; Cells, Cultured; Dimerization; Endothelium, Vascular; Enzyme Inhibitors; Ligands; Phosphorylation; Precipitin Tests; Protein Binding; Protein Phosphatase 1; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Receptor, Platelet-Derived Growth Factor beta; Recombinant Proteins; Sepharose; Swine; Transfection; Tyrosine; Vanadates | 2001 |
Tyrosine phosphorylation translocates beta-catenin from cell-->cell interface to the cytoplasm, but does not significantly enhance the LEF-1-dependent transactivating function.
Topics: 3T3 Cells; Animals; beta Catenin; Biological Transport; Cell Communication; Cell Membrane; Colonic Neoplasms; Cyclin D1; Cytoplasm; Cytoskeletal Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression; Humans; Luciferases; Lymphoid Enhancer-Binding Factor 1; Mice; Phosphorylation; Protein Tyrosine Phosphatases; Trans-Activators; Transcription Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
Interaction of the catch-loop tyrosine beta Y317 with the metal at catalytic site 3 of Chlamydomonas chloroplast F1-ATPase.
Topics: Adenosine Triphosphate; Animals; Catalysis; Catalytic Domain; Chlamydomonas reinhardtii; Chloroplasts; Electron Spin Resonance Spectroscopy; Kinetics; Ligands; Magnesium; Mutagenesis, Site-Directed; Proton-Translocating ATPases; Tyrosine; Vanadates; Vanadium | 2001 |
Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Biological Transport; Cell Membrane; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Humans; Molecular Sequence Data; Mutation; Phosphorylation; Protein Serine-Threonine Kinases; Sequence Homology, Amino Acid; src-Family Kinases; Tyrosine; Vanadates | 2001 |
Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling module.
Topics: Adaptor Proteins, Signal Transducing; Animals; B-Lymphocytes; Base Sequence; Carrier Proteins; Cell Line; DNA Primers; Enzyme Inhibitors; Enzyme Precursors; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Isoenzymes; Male; Mice; Mice, Knockout; Mice, Transgenic; Nuclear Proteins; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Syk Kinase; Type C Phospholipases; Tyrosine; Vanadates; Viral Matrix Proteins | 2001 |
Mechanisms of regulation of tyrosine phosphorylation of NMDA receptor subunit 2B after cerebral ischemia/reperfusion.
Topics: Animals; Calcium Channel Blockers; Genistein; Gerbillinae; Hippocampus; Ischemic Attack, Transient; Ketamine; Nifedipine; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, N-Methyl-D-Aspartate; Reperfusion Injury; Synaptosomes; Tyrosine; Vanadates | 2000 |
Growth-inhibitory effect of a streptococcal antitumor glycoprotein on human epidermoid carcinoma A431 cells: involvement of dephosphorylation of epidermal growth factor receptor.
Topics: Antibiotics, Antineoplastic; Bacterial Proteins; Carcinoma, Squamous Cell; Catalase; Cell Division; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Glycoproteins; Growth Inhibitors; GTP-Binding Proteins; Humans; MAP Kinase Signaling System; Pertussis Toxin; Phosphorylation; Precipitin Tests; Protein Tyrosine Phosphatases; Tumor Cells, Cultured; Tyrosine; Vanadates; Virulence Factors, Bordetella | 2001 |
Tyrosine phosphorylation following alterations in arteriolar intraluminal pressure and wall tension.
Topics: Angiotensin II; Animals; Antibody Specificity; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Colforsin; Endothelium, Vascular; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phosphorylation; Phosphotyrosine; Physical Stimulation; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrphostins; Vanadates; Vasoconstriction; Vasodilator Agents; Verapamil | 2001 |
Peroxisome proliferator-activated receptor gamma ligands inhibit mitogenic induction of p21(Cip1) by modulating the protein kinase Cdelta pathway in vascular smooth muscle cells.
Topics: Acetophenones; Adenoviridae; Animals; Aorta, Thoracic; Apoptosis; Benzopyrans; Blotting, Western; Carbazoles; Cell Division; Cells, Cultured; Chromans; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cycloheximide; Dose-Response Relationship, Drug; Down-Regulation; Enzyme Inhibitors; Hydroquinones; Indoles; Insulin; Isoenzymes; Kinetics; Ligands; Mice; Mitogens; Models, Biological; Muscle, Smooth, Vascular; Phosphorylation; Platelet-Derived Growth Factor; Precipitin Tests; Protein Kinase C; Protein Kinase C-delta; Protein Processing, Post-Translational; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; RNA; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Time Factors; Transcription Factors; Troglitazone; Tyrosine; Up-Regulation; Vanadates | 2001 |
Phosphorylation-induced activation of tilapia nonspecific cytotoxic cells by serum cytokines.
Topics: Animals; Antibodies, Monoclonal; Apoptosis; Benzoquinones; Blotting, Western; Camptothecin; Cell Cycle; Cold Temperature; Cytokines; Cytotoxicity, Immunologic; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Female; Flow Cytometry; Killer Cells, Natural; Kinetics; Lactams, Macrocyclic; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Male; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Quinones; Rifabutin; Stress, Physiological; Tilapia; Tyrosine; Vanadates | 2001 |
Direct effect of bispecific anti-CD33 x anti-CD64 antibody on proliferation and signaling in myeloid cells.
Topics: Antibodies, Bispecific; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cell Division; Humans; Interferon-gamma; Leukemia, Myeloid, Acute; Monocytes; Phagocytosis; Phosphorylation; Receptors, IgG; Sialic Acid Binding Ig-like Lectin 3; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
Modulation of nicotinic acetylcholine receptor turnover by tyrosine phosphorylation in rat myotubes.
Topics: Animals; Biotinylation; Bungarotoxins; Cells, Cultured; Cytoskeleton; Enzyme Inhibitors; Iodine Radioisotopes; Muscle Fibers, Skeletal; Neuromuscular Junction; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Tyrosine; Vanadates | 2001 |
Ceramide accelerates dephosphorylation of extracellular signal-regulated kinase 1/2 to decrease prostaglandin D(2) production in RBL-2H3 cells.
Topics: Animals; Antigens; Arachidonic Acid; Cell Line; Ceramides; Dose-Response Relationship, Drug; Immunoblotting; Mast Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phospholipase D; Phospholipases A; Phosphorylation; Prostaglandin D2; Protein Tyrosine Phosphatases; Rats; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
Tyrosine phosphorylation of human keratinocyte beta-catenin and plakoglobin reversibly regulates their binding to E-cadherin and alpha-catenin.
Topics: alpha Catenin; Antigens, CD; beta Catenin; Cadherins; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cytoskeletal Proteins; Desmoplakins; gamma Catenin; Humans; Keratinocytes; Phosphorylation; Reference Values; Tissue Distribution; Trans-Activators; Tyrosine; Vanadates | 2001 |
SH2 domain-containing inositol polyphosphate 5'-phosphatase is the main mediator of the inhibitory action of the mast cell function-associated antigen.
Topics: Amino Acid Sequence; Animals; beta-N-Acetylhexosaminidases; Enzyme Inhibitors; Immunosuppressive Agents; Lectins, C-Type; Mast Cells; Membrane Glycoproteins; Molecular Sequence Data; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Binding; Rats; Receptors, IgE; src Homology Domains; src-Family Kinases; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
Tyrosine phosphatases SHP-1 and SHP-2 are associated with distinct tyrosine-phosphorylated proteins.
Topics: Animals; Cattle; Cell Line; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Organ Specificity; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proteins; Rats; SH2 Domain-Containing Protein Tyrosine Phosphatases; Tyrosine; Vanadates | 2002 |
Cytokine signaling: STATS in plasma membrane rafts.
Topics: beta-Cyclodextrins; Blotting, Western; Caveolin 1; Caveolins; Cell Membrane; Cholesterol; Cyclodextrins; Cytokines; Detergents; DNA; DNA-Binding Proteins; Glucose; Humans; Interferon gamma Receptor; Interferon-gamma; Interleukin-6; Membrane Microdomains; Membrane Proteins; Octoxynol; Phosphorylation; Protein Binding; Receptors, Interferon; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Subcellular Fractions; Trans-Activators; Tumor Cells, Cultured; Tyrosine; Vanadates | 2002 |
alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells.
Topics: alpha-Synuclein; Animals; Blood Proteins; Blotting, Western; Brain; Cell Line; Cytoplasm; DNA, Complementary; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Glutathione Transferase; Humans; Microscopy, Fluorescence; Mutation; Nerve Tissue Proteins; Phospholipase D; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Synucleins; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tyrosine; Vanadates | 2002 |
Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Motifs; Amyloid beta-Protein Precursor; Animals; Apoptosis; Binding Sites; Brain; Cell Differentiation; Cell Line; Cell Membrane; COS Cells; Cytoplasm; Enzyme Inhibitors; Glutathione Transferase; Humans; Immunoblotting; Mice; Mice, Inbred BALB C; Models, Biological; Nerve Tissue Proteins; Neuroblastoma; Neuropeptides; Phosphorylation; Precipitin Tests; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Proteins; Receptor, trkA; Recombinant Fusion Proteins; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Src Homology 2 Domain-Containing, Transforming Protein 3; Transcription, Genetic; Tyrosine; Vanadates | 2002 |
SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptor.
Topics: Binding Sites; Blotting, Western; Cells, Cultured; Humans; Intracellular Signaling Peptides and Proteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Transfection; Tyrosine; Vanadates | 2002 |
Evidence that increased tyrosine phosphorylation causes disassembly of adherens junctions but does not perturb paracellular permeability in Caco-2 cells.
Topics: Actins; Adherens Junctions; Caco-2 Cells; Cadherins; Humans; Permeability; Phosphorylation; Protein Tyrosine Phosphatases; Tight Junctions; Tyrosine; Vanadates | 2001 |
Cloning and characterization of a testis and brain-specific isoform of mouse 3'-phosphoinositide-dependent protein kinase-1, mPDK-1 beta.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Aging; Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Brain; CHO Cells; Cloning, Molecular; Cricetinae; Female; Humans; Insulin; Isoenzymes; Male; Mice; Molecular Sequence Data; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Sequence Alignment; Spermatogenesis; src-Family Kinases; Testis; Tyrosine; Vanadates | 2002 |
N-terminal tyrosine residues within the potassium channel Kir3 modulate GTPase activity of Galphai.
Topics: Amino Acid Motifs; Animals; Arginine; Brain-Derived Neurotrophic Factor; Catalytic Domain; Enzyme Activation; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Glutamine; GTP Phosphohydrolases; GTP-Binding Protein alpha Subunit, Gi2; GTP-Binding Protein alpha Subunits, Gi-Go; Hydrolysis; Kinetics; Models, Chemical; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Inwardly Rectifying; Protein Binding; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Receptor, trkB; Receptors, Opioid, mu; RGS Proteins; RNA, Complementary; Tyrosine; Vanadates; Xenopus | 2002 |
Syndecan-4 modulates focal adhesion kinase phosphorylation.
Topics: Animals; Blotting, Western; Cell Adhesion; Cells, Cultured; DNA, Complementary; Fibroblasts; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Kinetics; Membrane Glycoproteins; Mice; Microscopy, Fluorescence; Models, Biological; Phosphorylation; Protein Kinase C; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteoglycans; rho GTP-Binding Proteins; Signal Transduction; Syndecan-4; Tetradecanoylphorbol Acetate; Transfection; Tyrosine; Vanadates | 2002 |
Src-induced phosphorylation of caveolin-2 on tyrosine 19. Phospho-caveolin-2 (Tyr(P)19) is localized near focal adhesions, remains associated with lipid rafts/caveolae, but no longer forms a high molecular mass hetero-oligomer with caveolin-1.
Topics: 3T3 Cells; Animals; Caveolae; Caveolin 1; Caveolin 2; Caveolins; COS Cells; Membrane Microdomains; Mice; Molecular Weight; Phosphorylation; Rabbits; src Homology Domains; src-Family Kinases; Tyrosine; Vanadates | 2002 |
BCR mutants deficient in ligand-independent and more sensitive for ligand-dependent signaling.
Topics: Antigens; Humans; Immunoglobulin D; Mutation; Phosphorylation; Receptors, Antigen, B-Cell; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 2002 |
Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase.
Topics: Animals; Carcinoma; COS Cells; Culture Media, Serum-Free; Enzyme Inhibitors; Female; Genes, Reporter; Humans; Insulin-Like Growth Factor I; Mutagenesis, Site-Directed; Ovarian Neoplasms; Peptide Mapping; Phosphatidylinositol 3-Kinases; Phosphopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Tumor Cells, Cultured; Tyrosine; Vanadates | 2002 |
Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation.
Topics: Breast Neoplasms; Cell Line, Transformed; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation, Enzymologic; Humans; Immunoblotting; Isoenzymes; Oligonucleotides, Antisense; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Receptor, EphA2; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates | 2002 |
ATP binding/hydrolysis by and phosphorylation of peroxisomal ATP-binding cassette proteins PMP70 (ABCD3) and adrenoleukodystrophy protein (ABCD1).
Topics: Adenosine Triphosphate; Animals; ATP Binding Cassette Transporter, Subfamily D, Member 1; ATP-Binding Cassette Transporters; Hydrolysis; Liver; Magnesium; Membrane Proteins; Peroxisomes; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Rats; Tyrosine; Ultraviolet Rays; Vanadates | 2002 |
Induction of rapid and reversible cytokeratin filament network remodeling by inhibition of tyrosine phosphatases.
Topics: 14-3-3 Proteins; Cytoplasmic Granules; Enzyme Inhibitors; Eukaryotic Cells; Fluorescent Antibody Technique; Green Fluorescent Proteins; Intermediate Filament Proteins; Intermediate Filaments; Keratins; Luminescent Proteins; Microscopy, Electron; Phosphorylation; Plectin; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Tumor Cells, Cultured; Tyrosine; Tyrosine 3-Monooxygenase; Vanadates | 2002 |
Temporal pattern of NFkappaB activation influences apoptotic cell fate in a stimuli-dependent fashion.
Topics: Apoptosis; Base Sequence; Cell Lineage; DNA Primers; HeLa Cells; Humans; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; RNA, Antisense; Serine; Signal Transduction; Tumor Necrosis Factor-alpha; Tyrosine; Ultraviolet Rays; Vanadates | 2002 |
Inhibition of protein tyrosine/mitogen-activated protein kinase phosphatase activity is associated with D2 dopamine receptor supersensitivity in a rat model of Parkinson's disease.
Topics: Animals; Behavior, Animal; Corpus Striatum; Disease Models, Animal; Dopamine Agonists; Oxidopamine; Parkinson Disease; PC12 Cells; Phosphorylation; Protein Tyrosine Phosphatases; Quinpirole; Rats; Receptors, Dopamine D2; Sympatholytics; Tyrosine; Vanadates | 2002 |
c-Src binds alpha II spectrin's Src homology 3 (SH3) domain and blocks calpain susceptibility by phosphorylating Tyr1176.
Topics: Animals; Apoptosis; Binding Sites; Calcium; Calpain; Cell Line; Dogs; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Endocytosis; Glutathione Transferase; Kinetics; Marine Toxins; Models, Biological; Oxocins; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Spectrin; src Homology Domains; src-Family Kinases; Time Factors; Tyrosine; Vanadates | 2003 |
Subunit-specific modulation of KCNQ potassium channels by Src tyrosine kinase.
Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Electric Conductivity; Enzyme Inhibitors; KCNQ2 Potassium Channel; KCNQ3 Potassium Channel; Kinetics; Muscarinic Agonists; Mutation; Neurons; Patch-Clamp Techniques; Phosphorylation; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Subunits; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Sprague-Dawley; Superior Cervical Ganglion; Tyrosine; Vanadates | 2003 |
Stimulation of glucose uptake by chronic vanadate pretreatment in cardiomyocytes requires PI 3-kinase and p38 MAPK activation.
Topics: Androstadienes; Animals; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Inhibitors; Glucose; Heart; Imidazoles; Immunoblotting; Male; Mitogen-Activated Protein Kinases; Myocardium; p38 Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; Rats; Rats, Sprague-Dawley; Receptor, Insulin; Signal Transduction; Stimulation, Chemical; Transcription, Genetic; Tyrosine; Vanadates; Wortmannin | 2003 |
Protein tyrosine phosphatase activity regulates endothelial cell-cell interactions, the paracellular pathway, and capillary tube stability.
Topics: Adherens Junctions; Animals; Antigens, CD; beta Catenin; Cadherins; Capillaries; Carbon Radioisotopes; Cattle; Cell Movement; Chromium Radioisotopes; Cytoskeletal Proteins; Desmoplakins; Endothelium, Vascular; Enzyme Inhibitors; Neovascularization, Physiologic; Neutrophils; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Pulmonary Artery; Serum Albumin, Bovine; Trans-Activators; Tyrosine; Vanadates | 2003 |
Tyrosine phosphorylation of a novel 100-kDa protein coupled to CD28 in resting human T cells is enhanced by a signal through TCR/CD3 complex.
Topics: Calcimycin; CD28 Antigens; Enzyme Inhibitors; Humans; Immunoblotting; Jurkat Cells; Lymphocyte Activation; Naphthalenes; Phosphoproteins; Phosphorylation; Precipitin Tests; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 2003 |
Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation.
Topics: Amino Acid Sequence; Blood Proteins; Blotting, Western; DNA; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Hydrogen Peroxide; Immunoblotting; Molecular Sequence Data; Mutation; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Recombinant Proteins; Signal Transduction; Time Factors; Transfection; Tyrosine; Vanadates | 2003 |
Different patterns of regulation of Tyr-phosphorylated STAT1 and STAT3 in human hepatoma Hep3B cells by the phosphatase inhibitor orthovanadate.
Topics: Biological Transport, Active; Carcinoma, Hepatocellular; DNA-Binding Proteins; DNA, Neoplasm; Drug Stability; Enzyme Inhibitors; Humans; Interferon-gamma; Interleukin-6; Kinetics; Liver Neoplasms; Phosphorylation; Protein Tyrosine Phosphatases; Recombinant Proteins; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Tumor Cells, Cultured; Tyrosine; Vanadates | 2003 |
Activation of phospholipase D is not mediated by direct phosphorylation on tyrosine residues.
Topics: Animals; Enzyme Activation; Enzyme Inhibitors; Isoenzymes; PC12 Cells; Phospholipase D; Phosphorylation; Phosphotyrosine; Precipitin Tests; Rats; Tyrosine; Vanadates | 2003 |
Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Blotting, Northern; Blotting, Western; Carrier Proteins; CHO Cells; Cricetinae; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Insulin; Intracellular Signaling Peptides and Proteins; Kidney; Liver; MAP Kinase Signaling System; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Signal Transduction; src Homology Domains; Time Factors; Tissue Distribution; Transfection; Tyrosine; Vanadates | 2003 |
Platelet endothelial cell adhesion molecule-1 (PECAM-1) inhibits low density lipoprotein-induced signaling in platelets.
Topics: Amino Acid Motifs; Blood Platelets; Blotting, Western; Cross-Linking Reagents; Cytosol; Down-Regulation; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Lipoproteins, LDL; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Peptides; Phospholipases A; Phospholipases A2; Phosphoprotein Phosphatases; Phosphorylation; Platelet Endothelial Cell Adhesion Molecule-1; Signal Transduction; Threonine; Time Factors; Tyrosine; Vanadates | 2003 |
Vanadate and rapamycin synergistically enhance insulin-stimulated glucose uptake.
Topics: Animals; Cell Line; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Drug Synergism; Glucose; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Leupeptins; Multienzyme Complexes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoproteins; Phosphorylation; Proteasome Endopeptidase Complex; Sirolimus; Tyrosine; Vanadates | 2003 |
Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.
Topics: 3T3 Cells; Alleles; Animals; Binding Sites; Catalysis; Cell Line; Cell Transformation, Neoplastic; DNA; Enzyme Activation; Enzyme Inhibitors; Genes, Reporter; GTP Phosphohydrolases; Guanine Nucleotide Exchange Factors; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; Oncogene Proteins; Phosphorylation; Plasmids; Promoter Regions, Genetic; Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-vav; Proto-Oncogene Proteins pp60(c-src); rac1 GTP-Binding Protein; Sulfonamides; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Time Factors; Transfection; Tyrosine; Vanadates | 2003 |
Involvement of the tyrosine phosphorylation on GSH transport in NIH3T3 fibroblasts.
Topics: Animals; Biological Transport; Fibroblasts; Glucose; Glutathione; Hydrogen Peroxide; Mice; Mutation; NIH 3T3 Cells; Oxidants; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Platelet-Derived Growth Factor; Tyrosine; Vanadates | 2003 |
Inhibition of IFN-gamma-mediated inducible nitric oxide synthase induction by the peroxisome proliferator-activated receptor gamma agonist, 15-deoxy-delta 12,14-prostaglandin J2, involves inhibition of the upstream Janus kinase/STAT1 signaling pathway.
Topics: Acetylcysteine; Animals; Antioxidants; Cell Line; DNA-Binding Proteins; Down-Regulation; Enzyme Induction; Glutathione; HT29 Cells; Humans; Interferon Regulatory Factor-1; Interferon-gamma; Interleukin-6; Janus Kinase 2; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Peroxisomes; Phosphoproteins; Phosphorylation; Prostaglandin D2; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Signal Transduction; STAT1 Transcription Factor; STAT3 Transcription Factor; Trans-Activators; Transcription Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 2003 |
Keratinocyte adherens junctions initiate nuclear signaling by translocation of plakoglobin from the membrane to the nucleus.
Topics: Adherens Junctions; beta Catenin; Biological Transport; Cell Membrane; Cell Nucleus; Culture Techniques; Cytoskeletal Proteins; Desmoplakins; DNA-Binding Proteins; gamma Catenin; Humans; Keratinocytes; Lymphoid Enhancer-Binding Factor 1; Phosphorylation; Promoter Regions, Genetic; Signal Transduction; Trans-Activators; Transcription Factors; Transcription, Genetic; Tyrosine; Vanadates | 2003 |
Cbl-mediated ubiquitinylation and negative regulation of Vav.
Topics: Animals; Cell Line; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; Immunoblotting; Jurkat Cells; Luciferases; Mice; Mice, Transgenic; Models, Genetic; Mutation; Oncogene Protein v-cbl; Oncogene Proteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Mas; Proto-Oncogene Proteins c-vav; Retroviridae Proteins, Oncogenic; Signal Transduction; Time Factors; Transfection; Tyrosine; Ubiquitin; Vanadates | 2003 |
A peroxovanadium compound stimulates muscle glucose transport as powerfully as insulin and contractions combined.
Topics: Androstadienes; Animals; Chromones; Enzyme Inhibitors; Glucose; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Male; Morpholines; Muscle Contraction; Muscle, Skeletal; Organometallic Compounds; Phenanthrolines; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Physical Exertion; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Serine; Tyrosine; Vanadates; Wortmannin | 2003 |
DNA binding controls inactivation and nuclear accumulation of the transcription factor Stat1.
Topics: Active Transport, Cell Nucleus; Antibodies, Monoclonal; Cell Nucleus; Cytoplasm; DNA; DNA-Binding Proteins; Enzyme Inhibitors; HeLa Cells; Humans; Interferon-gamma; Models, Biological; Mutation; Phosphorylation; Recombinant Proteins; STAT1 Transcription Factor; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine; Vanadates | 2003 |
Immunoglobulin mu heavy chains do not mediate tyrosine phosphorylation of Ig alpha from the ER-cis-Golgi.
Topics: Animals; Antigens, CD; B-Lymphocyte Subsets; CD79 Antigens; Cell Line, Tumor; Clone Cells; Cytoplasm; Endoplasmic Reticulum; Enzyme Activation; Golgi Apparatus; Immunoglobulin Heavy Chains; Immunoglobulin mu-Chains; Mice; Phosphorylation; Protein Transport; Receptors, Antigen, B-Cell; Signal Transduction; src-Family Kinases; Stem Cells; Subcellular Fractions; Tyrosine; Vanadates | 2003 |
Tyrosine kinase p56lck regulates cell motility and nuclear factor kappaB-mediated secretion of urokinase type plasminogen activator through tyrosine phosphorylation of IkappaBalpha following hypoxia/reoxygenation.
Topics: Active Transport, Cell Nucleus; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Nucleus; DNA, Complementary; Enzyme Inhibitors; Genes, Reporter; Humans; Hydrogen Peroxide; Hypoxia; I-kappa B Proteins; Luciferases; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Microscopy, Fluorescence; Models, Biological; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidation-Reduction; Oxygen; Phosphorylation; Plasmids; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Serine; Signal Transduction; Time Factors; Transfection; Tyrosine; Urokinase-Type Plasminogen Activator; Vanadates | 2003 |
Tyrosine phosphorylation of rod cyclic nucleotide-gated channels switches off Ca2+/calmodulin inhibition.
Topics: Animals; Calcium; Calmodulin; Cattle; Cyclic Nucleotide-Gated Cation Channels; Eye Proteins; Ion Channel Gating; Ion Channels; Microinjections; Mutation; Oocytes; Patch-Clamp Techniques; Phosphorylation; Retinal Rod Photoreceptor Cells; RNA, Complementary; Tyrosine; Vanadates; Xenopus laevis | 2003 |
Characterization of two mosquito STATs, AaSTAT and CtSTAT. Differential regulation of tyrosine phosphorylation and DNA binding activity by lipopolysaccharide treatment and by Japanese encephalitis virus infection.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Blotting, Western; Cell Line; Cell Nucleus; Culicidae; DNA-Binding Proteins; DNA, Complementary; Dose-Response Relationship, Drug; Drosophila; Encephalitis Virus, Japanese; Female; Gene Expression Regulation; Genes, Reporter; Humans; Insect Proteins; Lipopolysaccharides; Male; Molecular Sequence Data; Phosphorylation; Phylogeny; Plasmids; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Sex Factors; Signal Transduction; STAT Transcription Factors; Time Factors; Tissue Distribution; Trans-Activators; Transcription, Genetic; Transcriptional Activation; Tyrosine; Vanadates | 2004 |
Angiotensin II mediates Tyr-dephosphorylation in rat fetal kidney membranes.
Topics: Angiotensin II; Animals; Blotting, Western; Cell Membrane; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Female; Imidazoles; Immunoblotting; Kidney; Oligopeptides; Phosphorylation; Phosphotyrosine; Pyridines; Rats; Rats, Inbred WKY; Signal Transduction; Tyrosine; Vanadates | 2003 |
Pervanadate-induced reverse translocation and tyrosine phosphorylation of phorbol ester-stimulated protein kinase C betaII are mediated by Src-family tyrosine kinases in porcine neutrophils.
Topics: Animals; Cell Membrane; Cytosol; Enzyme Activation; Enzyme Inhibitors; Immunoblotting; Neutrophils; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinase C beta; Protein Transport; Protein Tyrosine Phosphatases; Pyrimidines; src-Family Kinases; Swine; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 2004 |
The tyrosine phosphatase inhibitor bis(maltolato)oxovanadium attenuates myocardial reperfusion injury by opening ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Potassium Channels; Protein Tyrosine Phosphatases; Pyrones; Rats; Rats, Wistar; Time Factors; Tyrosine; Vanadates | 2004 |
Tyrosine phosphorylation-dependent activation of NFkappaB is compromised in T cells from the elderly.
Topics: Adult; Aged; Aged, 80 and over; Aging; Enzyme Inhibitors; Humans; Hydrogen Peroxide; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Tyrosine Phosphatases; T-Lymphocytes; Tyrosine; Vanadates | 2004 |
A flow cytometric assay for global estimation of tyrosine phosphorylation associated with capacitation of spermatozoa from two marsupial species, the tammar wallaby (Macropus eugenii) and the brushtail possum (Trichosurus vulpecula).
Topics: Animals; Cells, Cultured; Coculture Techniques; Cyclic AMP; Enzyme Inhibitors; Female; Flow Cytometry; Macropodidae; Male; Marsupialia; Opossums; Oviducts; Phosphorylation; Protein Tyrosine Phosphatases; Sheep; Signal Transduction; Sperm Capacitation; Spermatozoa; Staurosporine; Tyrosine; Vanadates | 2004 |
Activation of vascular endothelial growth factor receptor-3 and its downstream signaling promote cell survival under oxidative stress.
Topics: Cell Line; Cell Survival; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Lymphedema; Mutation, Missense; Oncogene Protein v-akt; Oxidative Stress; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Kinase C; Pyrimidines; Recombinant Proteins; Retroviridae Proteins, Oncogenic; Signal Transduction; src Homology Domains; src-Family Kinases; Tyrosine; Vanadates; Vascular Endothelial Growth Factor Receptor-3 | 2004 |
Structure of human PRL-3, the phosphatase associated with cancer metastasis.
Topics: Amino Acid Sequence; Binding Sites; Enzyme Inhibitors; Humans; Immediate-Early Proteins; Ions; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Phosphates; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Sequence Homology, Amino Acid; Tyrosine; Vanadates | 2004 |
B-cell signal transduction: tyrosine phosphorylation, kinase activity, and calcium mobilization.
Topics: Animals; B-Lymphocytes; Calcium Signaling; Chickens; Child, Preschool; Enzyme Inhibitors; Flow Cytometry; Herpesvirus 4, Human; Humans; Male; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 2004 |
Interactions between NMDA receptors and mGlu5 receptors expressed in HEK293 cells.
Topics: Animals; Arsenicals; Cell Line; Drug Synergism; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Gene Expression; Genistein; Glycine; Humans; N-Methylaspartate; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor Cross-Talk; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Receptors, N-Methyl-D-Aspartate; Recombinant Fusion Proteins; Resorcinols; Staurosporine; Thapsigargin; Transfection; Tyrosine; Vanadates | 2004 |
Role of tyrosine phosphorylation in the regulation of cleavage secretion of angiotensin-converting enzyme.
Topics: Animals; Carcinogens; Cell Line; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Heat-Shock Proteins; Kidney; Mass Spectrometry; Mice; Mitogen-Activated Protein Kinases; Molecular Chaperones; p38 Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Structure, Tertiary; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 2004 |
Activation of RBL-2H3 mast cells is dependent on tyrosine phosphorylation of phospholipase D2 by Fyn and Fgr.
Topics: Animals; Cell Line; Enzyme Activation; Enzyme Inhibitors; Humans; Mast Cells; Phospholipase D; Phosphorylation; Point Mutation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Pyrimidines; Rats; Receptors, IgE; RNA, Small Interfering; src-Family Kinases; Tyrosine; Vanadates | 2004 |
Negative regulation of T cell receptor signaling by Siglec-7 (p70/AIRM) and Siglec-9.
Topics: Amino Acid Motifs; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blotting, Western; Cell Separation; Cytoplasm; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Genes, Reporter; Humans; Immunoprecipitation; Jurkat Cells; Lectins; Ligands; Luciferases; Microscopy, Fluorescence; Models, Biological; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Sialic Acid Binding Ig-like Lectin 3; Sialic Acid Binding Immunoglobulin-like Lectins; Signal Transduction; T-Lymphocytes; Time Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 2004 |
A unique mechanism for cyclic adenosine 3',5'-monophosphate-induced increase of 32-kDa tyrosine-phosphorylated protein in boar spermatozoa.
Topics: Acrosome; Animals; beta-Cyclodextrins; Calcium; Chelating Agents; Cyclic AMP; Egtazic Acid; In Vitro Techniques; Male; Phenols; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Spermatozoa; Swine; Tyrosine; Vanadates | 2004 |
Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.
Topics: Adaptor Proteins, Signal Transducing; Adenoma; Adenomatous Polyposis Coli Protein; Alleles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Clathrin; Colorectal Neoplasms; Cyclooxygenase 2; Dinoprostone; Disease Progression; Enterocytes; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Genes, APC; HeLa Cells; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Intestinal Mucosa; Intestine, Small; Isoenzymes; Jurkat Cells; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Mutation; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recurrence; Signal Transduction; src-Family Kinases; Tissue Distribution; Transcriptional Activation; Tyrosine; Ubiquitin; Up-Regulation; Vanadates | 2004 |
c-Cbl binds to tyrosine-phosphorylated neurotrophin receptor p75 and induces its ubiquitination.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Humans; Phosphorylation; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Signal Transduction; Tyrosine; Ubiquitin; Ubiquitin-Protein Ligases; Vanadates | 2004 |
alpha-thrombin rapidly induces tyrosine phosphorylation of a novel, 74-78-kDa stress response protein(s) in lung fibroblast cells.
Topics: Animals; Blotting, Western; Cell Line; Cricetinae; Cytokines; Cytoplasm; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Immunoprecipitation; Interleukin-6; Lung; Mass Spectrometry; Membrane Proteins; Peptide Fragments; Peptides; Phosphorylation; Protein Binding; STAT3 Transcription Factor; Subcellular Fractions; Thrombin; Time Factors; Trans-Activators; Tyrosine; Vanadates | 2004 |
Recruitment of C-terminal Src kinase by the leukocyte inhibitory receptor CD85j.
Topics: Amino Acid Motifs; Animals; Antigens, CD; B-Lymphocytes; beta-Galactosidase; Blotting, Western; CSK Tyrosine-Protein Kinase; Cytoplasm; DNA; DNA Mutational Analysis; DNA, Complementary; Humans; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Leukocyte Immunoglobulin-like Receptor B1; Peptides; Phosphorylation; Phosphotransferases; Protein Binding; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Immunologic; src-Family Kinases; Transfection; Two-Hybrid System Techniques; Tyrosine; Vanadates | 2004 |
Human Ran cysteine 112 oxidation by pervanadate regulates its binding to keratins.
Topics: Actins; Cell Line, Tumor; Cell Movement; Cell Survival; Cell-Free System; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Immunoprecipitation; Keratins; Mass Spectrometry; Models, Biological; Mutation; Oxygen; Phosphorylation; Proteasome Inhibitors; Protein Binding; Proteomics; ran GTP-Binding Protein; Tyrosine; Vanadates | 2005 |
Carnosol inhibits beta-catenin tyrosine phosphorylation and prevents adenoma formation in the C57BL/6J/Min/+ (Min/+) mouse.
Topics: Abietanes; Adenoma; Animals; beta Catenin; Cadherins; Cell Adhesion; Cell Membrane; Colonic Neoplasms; Cytoskeletal Proteins; Enterocytes; Female; Intestine, Small; Mice; Mice, Inbred C57BL; Phenanthrenes; Phosphorylation; Rosmarinus; Trans-Activators; Tyrosine; Vanadates | 2005 |
Regulatory and necrotic volume increase in boar spermatozoa.
Topics: Animals; Annexin A5; Cell Size; Chloride Channels; Enzyme Inhibitors; Hypertonic Solutions; Male; Necrosis; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Protein-Tyrosine Kinases; Quinidine; Semen Preservation; Spermatozoa; Staining and Labeling; Staurosporine; Swine; Tamoxifen; Tyrosine; Vanadates | 2005 |
LAR receptor protein tyrosine phosphatases in the development and maintenance of excitatory synapses.
Topics: Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; beta Catenin; Blotting, Western; Brain; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cytoskeletal Proteins; Dendrites; Diagnostic Imaging; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Gene Expression Regulation, Developmental; Genistein; Green Fluorescent Proteins; Hippocampus; Humans; Immunohistochemistry; Immunoprecipitation; Membrane Potentials; Molecular Sequence Data; Mutagenesis; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-myc; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; RNA, Antisense; RNA, Small Interfering; Synapses; Time Factors; Trans-Activators; Transfection; Tyrosine; Vanadates | 2005 |
Rapid upregulation of alpha7 nicotinic acetylcholine receptors by tyrosine dephosphorylation.
Topics: Acetylcholine; alpha7 Nicotinic Acetylcholine Receptor; Animals; Biotinylation; Blotting, Western; Bungarotoxins; Choline; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Interactions; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agonists; Genistein; Hippocampus; Insulin; Interneurons; Iodine Isotopes; Ion Channel Gating; Membrane Potentials; Microinjections; Mutagenesis; N-Methylaspartate; Oocytes; Patch-Clamp Techniques; Phosphoric Monoester Hydrolases; Phosphorylation; Protein-Tyrosine Kinases; Radioligand Assay; Rats; Receptors, Nicotinic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; SNARE Proteins; Time Factors; Tyrosine; Up-Regulation; Vanadates; Xenopus | 2005 |
Modulation of protein tyrosine phosphatase activity alters the subunit assembly in native N-methyl-D-aspartate receptor complex.
Topics: Animals; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Inhibitors; Immunoprecipitation; In Vitro Techniques; Mass Spectrometry; Neurons; Phosphorylation; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Signal Transduction; src-Family Kinases; Tetrazolium Salts; Thiazoles; Tyrosine; Vanadates | 2005 |
Constitutive secretion of serum albumin requires reversible protein tyrosine phosphorylation events in trans-Golgi.
Topics: Animals; Biomarkers; Cells, Cultured; Enzyme Inhibitors; Genistein; Hepatocytes; Male; Phosphoprotein Phosphatases; Phosphorylation; Protein Transport; Protein-Tyrosine Kinases; Rats; Serum Albumin; Substrate Specificity; trans-Golgi Network; Tyrosine; Vanadates | 2005 |
Tyrosine phosphatase PTP1B interacts with TRPV6 in vivo and plays a role in TRPV6-mediated calcium influx in HEK293 cells.
Topics: Animals; Blotting, Western; Calcium; Calcium Channels; Cell Line; Cloning, Molecular; Green Fluorescent Proteins; Humans; Immunoprecipitation; Microscopy, Video; Phosphorylation; Plasmids; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Rats; Spectrometry, Fluorescence; src-Family Kinases; Time Factors; Transfection; TRPV Cation Channels; Tyrosine; Vanadates | 2005 |
Comparison of the effects of isoflurane and sevoflurane on protein tyrosine phosphorylation-mediated vascular contraction.
Topics: Anesthetics, Inhalation; Animals; Aorta, Thoracic; Enzyme Inhibitors; Genistein; In Vitro Techniques; Isoflurane; Male; Methyl Ethers; Muscle Contraction; Muscle, Smooth, Vascular; Phosphorylation; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Sevoflurane; Tyrosine; Vanadates | 2005 |
Involvement of BKCa alpha subunit tyrosine phosphorylation in vascular hyporesponsiveness of superior mesenteric artery following hemorrhagic shock in rats.
Topics: Animals; Genistein; Hypotension; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Mesenteric Artery, Superior; Muscle, Smooth, Vascular; Phosphorylation; Potassium Channels; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quaternary Ammonium Compounds; Rats; Rats, Wistar; Shock, Hemorrhagic; Time Factors; Tyrosine; Vanadates; Vascular Resistance; Vasodilation | 2005 |
Reactive oxygen species induce tyrosine phosphorylation of and Src kinase recruitment to NO-sensitive guanylyl cyclase.
Topics: Animals; Aorta; Blotting, Western; Chlorocebus aethiops; COS Cells; Enzyme Inhibitors; Glutathione Transferase; Guanylate Cyclase; Humans; Hydrogen Peroxide; Muscle, Smooth, Vascular; Nitric Oxide; PC12 Cells; Phosphorylation; Precipitin Tests; Rats; Rats, Wistar; Reactive Oxygen Species; Recombinant Fusion Proteins; Solubility; src-Family Kinases; Tyrosine; Vanadates; Vanadium Compounds | 2005 |
Src-mediated phosphorylation regulates subcellular distribution and activity of human inducible nitric oxide synthase.
Topics: Amino Acid Sequence; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Humans; Immunoblotting; Immunoprecipitation; Intestinal Mucosa; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins pp60(c-src); Sequence Homology, Amino Acid; Subcellular Fractions; Transfection; Tyrosine; Vanadates | 2006 |
Characterization of STAT5B phosphorylation correlating with expression of cytokine-inducible SH2-containing protein (CIS).
Topics: Animals; Cell Line; Cell Nucleus; Cells, Cultured; Electrophoretic Mobility Shift Assay; Immediate-Early Proteins; Interleukin-3; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Models, Molecular; Phosphorylation; Promoter Regions, Genetic; Protein Processing, Post-Translational; Serine; STAT5 Transcription Factor; Suppressor of Cytokine Signaling Proteins; T-Lymphocytes; Tyrosine; Vanadates | 2006 |
The vanadyl (VO2+) chelate bis(acetylacetonato)oxovanadium(IV) potentiates tyrosine phosphorylation of the insulin receptor.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Chelating Agents; Enzyme Activation; Glycogen; Glycogen Synthase; Hypoglycemic Agents; Insulin Resistance; Mice; Molecular Structure; Organometallic Compounds; Phosphorylation; Pyrones; Receptor, Insulin; Solutions; Tyrosine; Vanadates | 2005 |
Tyrosine phosphatase SHP-2 regulates IL-1 signaling in fibroblasts through focal adhesions.
Topics: Actinin; Adaptor Proteins, Signal Transducing; Animals; Cell Line; Cells, Cultured; Collagen; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibronectins; Focal Adhesions; Humans; Interleukin-1; Intracellular Signaling Peptides and Proteins; Mice; Mutation; Paxillin; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; RNA, Small Interfering; Signal Transduction; Transfection; Tyrosine; Vanadates | 2006 |
Tyrosine phosphorylation and the small GTPase rac cross-talk in regulation of endothelial barrier function.
Topics: Actins; Adherens Junctions; Antigens, CD; Cadherins; Capillary Permeability; Cell Communication; Cells, Cultured; Dose-Response Relationship, Drug; Electric Impedance; Endothelial Cells; Genes, Reporter; Green Fluorescent Proteins; Humans; Phosphorylation; Protein Tyrosine Phosphatases; rac1 GTP-Binding Protein; Time Factors; Transfection; Tyrosine; Vanadates; Vascular Endothelial Growth Factors | 2005 |
NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels.
Topics: Amino Acid Sequence; Animals; Calcium; Capsaicin; Cell Line; Cells, Cultured; DNA; DNA, Complementary; Electrophysiology; Gene Expression Regulation; Glutathione Transferase; Hot Temperature; Humans; Immunoblotting; Immunohistochemistry; Ion Channels; Mice; Models, Biological; Molecular Sequence Data; Mutation; Nerve Growth Factor; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Binding; Receptor, trkA; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Signal Transduction; Sodium; src-Family Kinases; Time Factors; Transfection; TRPV Cation Channels; Tyrosine; Vanadates | 2005 |
The structure of the transition state of the heterodimeric topoisomerase I of Leishmania donovani as a vanadate complex with nicked DNA.
Topics: Animals; Arginine; Catalytic Domain; Crystallography, X-Ray; Dimerization; DNA; DNA Topoisomerases, Type I; Histidine; Humans; Leishmania donovani; Macromolecular Substances; Models, Molecular; Molecular Structure; Protein Structure, Quaternary; Protozoan Proteins; Topoisomerase I Inhibitors; Tyrosine; Vanadates; Water | 2006 |
Maintenance of Bad phosphorylation prevents apoptosis of rat hepatic sinusoidal endothelial cells in vitro and in vivo.
Topics: 14-3-3 Proteins; Animals; Apoptosis; bcl-Associated Death Protein; Caspase 3; Caspase 9; Caspases; Cells, Cultured; Endothelial Cells; Enzyme Activation; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Liver; Male; Oncogene Protein v-akt; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Rats; Rats, Inbred F344; Rats, Wistar; Reperfusion Injury; Serine; Signal Transduction; Tyrosine; Vanadates | 2006 |
Akt inhibits MLK3/JNK3 signaling by inactivating Rac1: a protective mechanism against ischemic brain injury.
Topics: 14-3-3 Proteins; Animals; bcl-2-Associated X Protein; Biological Transport; Brain Ischemia; Caspase 3; Caspases; Cytochromes c; Cytosol; Enzyme Activation; Enzyme Inhibitors; Fas Ligand Protein; Hippocampus; Male; MAP Kinase Kinase Kinases; Membrane Glycoproteins; Mitochondria; Mitogen-Activated Protein Kinase 10; Mitogen-Activated Protein Kinase Kinase Kinase 11; Neuroprotective Agents; Phosphorylation; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Signal Transduction; Tumor Necrosis Factor Inhibitors; Tyrosine; Vanadates | 2006 |
The role of tyrosine kinase in prostaglandin E2 and vanadate-evoked contractions in rabbit duodenum in vitro.
Topics: Animals; Calcium; Carbachol; Dinoprostone; Dose-Response Relationship, Drug; Duodenum; Estrenes; Genistein; In Vitro Techniques; Indomethacin; Muscle Contraction; Muscle, Smooth; Phosphorylation; Protein-Tyrosine Kinases; Pyrrolidinones; Rabbits; Tyrosine; Tyrphostins; Vanadates; Verapamil | 2006 |
Interaction of vanadyl (VO2+) with ligands containing serine, tyrosine, and threonine.
Topics: Crystallography, X-Ray; Ligands; Models, Molecular; Molecular Conformation; Organometallic Compounds; Schiff Bases; Serine; Threonine; Tyrosine; Vanadates | 2006 |
Spred-2 steady-state levels are regulated by phosphorylation and Cbl-mediated ubiquitination.
Topics: Adaptor Proteins, Signal Transducing; Cells, Cultured; Epidermal Growth Factor; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-cbl; Repressor Proteins; RNA Interference; Tyrosine; Ubiquitin; Vanadates | 2006 |
Identification of tyrosines in the putative regulatory site of the Ca2+ channel TRPV6.
Topics: Amino Acid Sequence; Calcium Channels; Cells, Cultured; Humans; Point Mutation; Protein Tyrosine Phosphatases; src-Family Kinases; Transfection; TRPV Cation Channels; Two-Hybrid System Techniques; Tyrosine; Vanadates | 2007 |
Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach.
Topics: Amino Acid Sequence; Cell Adhesion; Enzyme Inhibitors; ErbB Receptors; HeLa Cells; Humans; Isotope Labeling; Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Tyrosine; Vanadates | 2007 |
Vanadate-induced inhibition of BCR-triggered apoptosis is coupled with tyrosine phosphorylation and induction of G2M growth arrest in Ramos-BL B cells.
Topics: Apoptosis; B-Lymphocytes; Burkitt Lymphoma; Cell Division; G2 Phase; Proto-Oncogene Proteins c-bcr; Receptors, Antigen, B-Cell; Signal Transduction; Tyrosine; Vanadates | 2007 |
Protein tyrosine dephosphorylation during copper-induced cell death in rice roots.
Topics: Cell Death; Copper; DNA Fragmentation; DNA, Plant; Oryza; Phosphorylation; Plant Proteins; Plant Roots; Protein Tyrosine Phosphatases; Tyrosine; Vanadates | 2007 |
c-Cbl is not required for ERK1/2-dependent degradation of BimEL.
Topics: Animals; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Fibroblasts; Humans; Membrane Proteins; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Phosphorylation; Proteasome Endopeptidase Complex; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Serine; Tamoxifen; Tyrosine; Ubiquitin; Vanadates | 2007 |
Pharmacological inhibition of GSK-3 is not strictly correlated with a decrease in tyrosine phosphorylation of residues 216/279.
Topics: Animals; Cell Line, Tumor; Enzyme Inhibitors; Glycogen Synthase Kinase 3; Lysophospholipids; Mice; Peptide Fragments; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Tyrosine; Vanadates | 2008 |
Characterization of the chicken CD200 receptor family.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; Cell Line; Chickens; Chromosomes; Genome; Glycosylation; Humans; Molecular Sequence Data; Molecular Weight; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Solubility; Tyrosine; Vanadates | 2008 |
Engagement of phospholipid scramblase 1 in activated cells: implication for phosphatidylserine externalization and exocytosis.
Topics: Animals; Calcimycin; Cell Line, Tumor; Cell Membrane; Detergents; Enzyme Inhibitors; Exocytosis; Ionophores; Microscopy, Confocal; Models, Biological; Phosphatidylserines; Phospholipid Transfer Proteins; Phosphorylation; Rats; Tyrosine; Vanadates | 2008 |
Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1.
Topics: Adaptor Proteins, Signal Transducing; Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Cell Line; Cytoskeletal Proteins; Enzyme Inhibitors; Ligands; Molecular Sequence Data; Phosphopeptides; Proto-Oncogene Proteins c-abl; src Homology Domains; Tyrosine; Vanadates | 2008 |
Geldanamycin inhibits tyrosine phosphorylation-dependent NF-kappaB activation.
Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; DNA; Gene Expression Regulation; Genes, src; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; I-kappa B Kinase; Jurkat Cells; Lactams, Macrocyclic; Molecular Structure; NF-kappa B; Phosphorylation; Protein Binding; RNA, Messenger; Tyrosine; Vanadates | 2008 |
Tyr-phosphorylation signals translocate RIN3, the small GTPase Rab5-GEF, to early endocytic vesicles.
Topics: Carrier Proteins; Cytoplasm; Enzyme Inhibitors; Guanine Nucleotide Exchange Factors; HeLa Cells; Humans; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Protein Transport; Protein Tyrosine Phosphatases; rab5 GTP-Binding Proteins; Sequence Deletion; Transport Vesicles; Tyrosine; Vanadates | 2008 |
Vanadate inhibits endoplasmic reticulum stress responses.
Topics: Animals; Blotting, Western; Cell Line, Tumor; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Glyceraldehyde-3-Phosphate Dehydrogenases; Heat-Shock Proteins; Mice; Mice, Inbred C57BL; Molecular Chaperones; Neuroglia; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Stress, Physiological; Transcription Factor CHOP; Tyrosine; Vanadates | 2008 |
Human kidney anion exchanger 1 localisation in MDCK cells is controlled by the phosphorylation status of two critical tyrosines.
Topics: Acid-Base Equilibrium; Amino Acid Substitution; Animals; Anion Exchange Protein 1, Erythrocyte; Bicarbonates; Buffers; Cell Line; Cell Membrane; Dogs; Enzyme Inhibitors; Humans; Kidney; Mutation, Missense; Phosphorylation; Protein Structure, Tertiary; Protein Transport; Tyrosine; Vanadates | 2008 |
Effect of vanadate on the chromatin configuration in pig GV-oocytes.
Topics: Animals; Bucladesine; Cell Differentiation; Chromatin; Cyclic AMP; Enzyme Inhibitors; Gonadotropins; Humans; Oocytes; Phosphoric Monoester Hydrolases; Swine; Time Factors; Tyrosine; Vanadates | 2009 |
Isolation of regulatory-competent, phosphorylated cytochrome C oxidase.
Topics: Animals; Cattle; Chromatography, Liquid; Electron Transport Complex IV; Mass Spectrometry; Mitochondria, Heart; Mitochondria, Liver; Phosphorylation; Protein Subunits; Spectrometry, Mass, Electrospray Ionization; Tyrosine; Vanadates | 2009 |
Regulatory role of tyrosine phosphorylation in the swelling-activated chloride current in isolated rabbit articular chondrocytes.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Cartilage, Articular; Cell Size; Chloride Channels; Chondrocytes; Cyclopentanes; Genistein; Indans; Male; Osmosis; Patch-Clamp Techniques; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rabbits; Tyrosine; Vanadates | 2009 |
A protein tyrosine phosphatase inhibitor, pervanadate, inhibits angiotensin II-Induced beta-arrestin cleavage.
Topics: Angiotensin II; Animals; Arrestins; beta-Arrestin 1; beta-Arrestins; Blotting, Western; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Enzyme Inhibitors; Green Fluorescent Proteins; Hydrolysis; Molybdenum; Phosphorylation; Protein Conformation; Protein Tyrosine Phosphatases; Rats; Receptor, Angiotensin, Type 1; Transfection; Tyrosine; Vanadates; Vasoconstrictor Agents | 2009 |
Cbl-associated protein is tyrosine phosphorylated by c-Abl and c-Src kinases.
Topics: Amino Acid Substitution; Cell Line, Tumor; CSK Tyrosine-Protein Kinase; Focal Adhesions; HeLa Cells; Humans; Immunoprecipitation; Insulin; Microfilament Proteins; Mutagenesis, Site-Directed; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; src-Family Kinases; Stress Fibers; Tyrosine; Vanadates | 2009 |
Tyrosine phosphorylation by Src within the cavity of the adenine nucleotide translocase 1 regulates ADP/ATP exchange in mitochondria.
Topics: Adenine Nucleotide Translocator 1; Adenosine Diphosphate; Adenosine Triphosphate; Computer Simulation; HeLa Cells; Humans; Hydrogen Peroxide; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mitochondria; Mitochondrial ADP, ATP Translocases; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myocardium; Nucleotide Transport Proteins; Phosphorylation; Protein Conformation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Stability; Protein Structure, Tertiary; Pyrimidines; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; src-Family Kinases; Structure-Activity Relationship; Transfection; Tyrosine; Vanadates | 2010 |
Regulation of human cardiac KCNQ1/KCNE1 channel by epidermal growth factor receptor kinase.
Topics: Animals; Cell Line; Electrophysiology; ErbB Receptors; Genistein; Humans; Ion Channel Gating; KCNQ1 Potassium Channel; Phosphorylation; Protein Kinase Inhibitors; Recombinant Proteins; src-Family Kinases; Tyrosine; Tyrphostins; Vanadates | 2010 |
Requirements for catalysis in the Cre recombinase active site.
Topics: Amino Acid Sequence; Amino Acid Substitution; Arginine; Biocatalysis; Catalytic Domain; Glutamic Acid; Histidine; Integrases; Lysine; Models, Molecular; Molecular Sequence Data; Recombination, Genetic; Tryptophan; Tyrosine; Vanadates | 2010 |
Prothoracicotropic hormone induces tyrosine phosphorylation in prothoracic glands of the silkworm, Bombyx mori.
Topics: Animals; Antibodies; Bombyx; Ecdysteroids; Extracellular Signal-Regulated MAP Kinases; Genistein; Insect Hormones; Larva; Naphthalenes; Organophosphonates; Phosphorylation; Protein Phosphatase 2; src-Family Kinases; Tyrosine; Vanadates | 2011 |
Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium.
Topics: Animals; Antigens, CD; Cadherins; Capillary Permeability; Cattle; Cells, Cultured; Claudin-5; Endothelium, Vascular; Humans; Membrane Proteins; Phosphorylation; Protein Tyrosine Phosphatases; Transforming Growth Factor beta1; Tyrosine; Vanadates | 2011 |
Regulation of membrane-cytoskeletal interactions by tyrosine phosphorylation of erythrocyte band 3.
Topics: Actins; Anion Exchange Protein 1, Erythrocyte; Ankyrins; Cell Membrane; Cross-Linking Reagents; Cytoskeleton; Erythrocyte Membrane; Erythrocytes; Humans; Immunoblotting; Phosphorylation; Protein Binding; Tyrosine; Vanadates | 2011 |
PLCβ1-SHP-2 complex, PLCβ1 tyrosine dephosphorylation and SHP-2 phosphatase activity: a new part of Angiotensin II signaling?
Topics: Angiotensin II; Blotting, Western; Cells, Cultured; Fibroblasts; Humans; Phospholipase C beta; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Receptor, Angiotensin, Type 1; RGS Proteins; Signal Transduction; Tyrosine; Vanadates | 2011 |
Human ether-à-go-go gene potassium channels are regulated by EGFR tyrosine kinase.
Topics: ErbB Receptors; Ether-A-Go-Go Potassium Channels; HEK293 Cells; Humans; Patch-Clamp Techniques; RNA Interference; Signal Transduction; Tyrosine; Tyrphostins; Vanadates | 2012 |
Tumor necrosis factor α stimulates expression and secretion of urokinase plasminogen activator in human dental pulp cells.
Topics: Cells, Cultured; Dental Pulp; Genistein; Humans; Interleukin-1; NF-kappa B; Phosphorylation; Plasminogen Activators; Pyrrolidines; Rifabutin; Thiocarbamates; Tumor Necrosis Factor-alpha; Tyrosine; Vanadates | 2012 |
Control of ALK (wild type and mutated forms) phosphorylation: specific role of the phosphatase PTP1B.
Topics: Anaplastic Lymphoma Kinase; Animals; Dimerization; Endoplasmic Reticulum; Humans; Mice; NIH 3T3 Cells; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor Protein-Tyrosine Kinases; src-Family Kinases; Transfection; Tyrosine; Vanadates | 2013 |
The anti-inflammatory compound BAY-11-7082 is a potent inhibitor of protein tyrosine phosphatases.
Topics: Animals; Anti-Inflammatory Agents; Catalytic Domain; Cell Line; Enzyme Inhibitors; Humans; Kinetics; Lipopolysaccharides; Macrophages; Mice; Models, Molecular; Nitriles; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Sulfones; Surface Properties; Tyrosine; Vanadates | 2013 |
Membrane depolarization-induced RhoA/Rho-associated kinase activation and sustained contraction of rat caudal arterial smooth muscle involves genistein-sensitive tyrosine phosphorylation.
Topics: Amides; Animals; Arteries; Calcium; Genistein; In Vitro Techniques; Male; Membrane Potentials; Muscle Contraction; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Phosphorylation; Potassium; Protein Kinase Inhibitors; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pyridines; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Tyrosine; Vanadates | 2013 |
A versatile spectrophotometric protein tyrosine phosphatase assay based on 3-nitrophosphotyrosine containing substrates.
Topics: Enzyme Inhibitors; HEK293 Cells; Humans; Kinetics; Protein Tyrosine Phosphatases; Spectrophotometry; Substrate Specificity; Tyrosine; Vanadates | 2014 |
Tyrosine phosphorylation modulates the vascular responses of mesenteric arteries from human colorectal tumors.
Topics: Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Mesenteric Arteries; Neovascularization, Pathologic; Organ Culture Techniques; Phosphorylation; Tyrosine; Vanadates; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2013 |
A systems toxicology approach identifies Lyn as a key signaling phosphoprotein modulated by mercury in a B lymphocyte cell model.
Topics: Animals; Autoimmune Diseases; B-Lymphocytes; Biomarkers; Cell Line; Chromatography, High Pressure Liquid; Mercury; Mercury Poisoning; Mice; Osmolar Concentration; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Receptors, Antigen, B-Cell; Signal Transduction; src-Family Kinases; Tandem Mass Spectrometry; Tyrosine; Vanadates | 2014 |
Redox-regulated pathway of tyrosine phosphorylation underlies NF-κB induction by an atypical pathway independent of the 26S proteasome.
Topics: Aclarubicin; Animals; Cell Line; Enzyme Activation; Humans; I-kappa B Kinase; Mice; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Signal Transduction; src-Family Kinases; Tyrosine; Vanadates | 2015 |
Pervanadate induces Mammalian Ste20 Kinase 3 (MST3) tyrosine phosphorylation but not activation.
Topics: Amino Acid Sequence; Animals; Dogs; Enzyme Assays; Enzyme Inhibitors; Gene Expression Regulation; HEK293 Cells; Humans; Kinetics; Madin Darby Canine Kidney Cells; Osmolar Concentration; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases; Signal Transduction; Tyrosine; Vanadates | 2016 |
Mercury alters endogenous phosphorylation profiles of SYK in murine B cells.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Mercury; Mice; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Receptors, Antigen, B-Cell; Signal Transduction; Syk Kinase; Tandem Mass Spectrometry; Tyrosine; Vanadates | 2017 |
Neuroprotective effects of a protein tyrosine phosphatase inhibitor against hippocampal excitotoxic injury.
Topics: Animals; Brain; Cell Death; Cell Survival; Excitatory Amino Acid Agonists; Female; Glutamic Acid; Hippocampus; Kainic Acid; Male; Neurons; Neuroprotective Agents; Neurotoxins; Protein Tyrosine Phosphatases; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Temporal Lobe; Tyrosine; Vanadates | 2019 |
Tyrosine Phosphorylation Regulates Plasma Membrane Expression and Stability of the Human Bile Acid Transporter ASBT (
Topics: Animals; Caco-2 Cells; Cell Membrane; Chlorocebus aethiops; COS Cells; Humans; Intestinal Mucosa; Leupeptins; Mutagenesis, Site-Directed; Organic Anion Transporters, Sodium-Dependent; Phosphorylation; Point Mutation; Proteasome Endopeptidase Complex; Protein Stability; Protein Tyrosine Phosphatases; Proteolysis; Pyrimidines; src-Family Kinases; Symporters; Tyrosine; Vanadates | 2019 |