vanadates has been researched along with pervanadate in 359 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 152 (42.34) | 18.2507 |
| 2000's | 174 (48.47) | 29.6817 |
| 2010's | 30 (8.36) | 24.3611 |
| 2020's | 3 (0.84) | 2.80 |
| Authors | Studies |
|---|---|
| Burroughs, S; Feinstein, MB; Huang, CK; Lau, LF; Pumiglia, KM | 1 |
| Araki, S; Ishibashi, S; Oishi, H; Okamura, N; Saeki, S; Yamaguchi, M; Yamane, H | 1 |
| Oliver, JM; Pfeiffer, JR | 1 |
| Modderman, PW; Sonnenberg, A; von dem Borne, AE | 1 |
| Ikebuchi, H; Nakanishi, M; Sawada, J; Teshima, R | 1 |
| Martinson, EA; Presek, P; Scheible, S | 1 |
| Ahmad, S; Hollenberg, MD; Laniyonu, A; Saifeddine, M | 2 |
| Barnes, DM; Miller, DS; Smith, JJ; Sykes, DB | 1 |
| Bordin, L; Clari, G; Dalla Vecchia, F; Moret, V; Moro, I | 1 |
| Feghali, CA; Wright, TM | 1 |
| Jones, PM; Persaud, SJ; Wheeler-Jones, CP | 1 |
| Meier, T; Perez, GM; Wallace, BG | 1 |
| Broadway, D; Wilden, PA | 1 |
| Abraham, RT; Kato, M; Kita, H | 1 |
| Chardin, P; Dubois, T; Franco, M; Geny, B; Lukowski, S; Paris, S; Russo Marie, F | 1 |
| Bennett, PA; Dixon, RJ; Finan, PM; Kellie, S | 1 |
| Brady-Kalnay, SM; Rimm, DL; Tonks, NK | 1 |
| Desiderio, S; Malek, SN; Yang, W | 1 |
| Houdebine, LM; Larose, M; Schindler, C; Tourkine, N | 1 |
| Breu, J; Petryniak, MA; Slack, BE; Srivastava, K; Wurtman, RJ | 1 |
| Aggarwal, BB; Singh, S | 1 |
| Batkin, M; Brakebusch, C; Varfolomeev, EE; Wallach, D | 1 |
| Arkinstall, S; Maundrell, K; Payton, M | 1 |
| Briscoe, CP; Cross, M; Martin, A; Wakelam, MJ | 1 |
| Haslam, J; Kessler, L; Lamb, P; Rosen, J; Seidel, HM; Stein, RB | 1 |
| Bianchini, L; Grinstein, S; Nanda, A; Wasan, S | 1 |
| Erwin, R; Evans, GA; Farrar, WL; Garcia, GG; Howard, OM | 1 |
| Shechter, Y; Shisheva, A | 2 |
| Husøy, T; Mikalsen, SO; Sanner, T | 1 |
| Ikonomov, O; Shechter, Y; Shisheva, A | 1 |
| Bennett, PA; Dixon, RJ; Kellie, S | 1 |
| Bos, JL; de Vries-Smits, AM; Ellis, C; Pronk, GJ | 1 |
| Abraham, RT; Burns, LA; Karnitz, L; Koretzky, GA; Secrist, JP | 1 |
| Bianchini, L; Grinstein, S; Todderud, G | 1 |
| Eckerskorn, C; Kirchgessner, H; Marie-Cardine, A; Meuer, SC; Schraven, B | 1 |
| Branton, PE; Fournel, M; Lee, JM; Veillette, A | 1 |
| Marunaka, Y; Shintani, Y | 1 |
| Saito, Y; Takagi, J | 1 |
| Diltz, CD; Fischer, EH; Tan, Z; You, M; Zhao, Z | 1 |
| Elberg, G; Li, J; Shechter, Y | 1 |
| Harbon, S; Leiber, D; Palmier, B | 1 |
| Auberger, P; Farahifar, D; Imbert, V; Mary, D; Peyron, JF; Rossi, B | 1 |
| Larbolette, O; Reth, M; Wienands, J | 1 |
| Ambudkar, IS; Sakai, T | 1 |
| Kaalhus, O; Mikalsen, SO | 2 |
| Fadool, DA; Holmes, TC; Levitan, IB | 1 |
| Banker, GA; Mandell, JW | 1 |
| Auberger, P; Baeuerle, PA; Farahifar, D; Imbert, V; Livolsi, A; Mueller-Dieckmann, C; Pahl, HL; Peyron, JF; Rossi, B; Rupec, RA; Traenckner, EB | 1 |
| Arbogast, A; Phelouzat, MA; Plastre, O; Proust, JJ; Quadri, RA | 1 |
| Donovan, JA; Langdon, WY; Ota, Y; Samelson, LE | 1 |
| Hashimoto, S; Ida, M; Imai, K; Kawashima, H | 1 |
| Lebakken, CS; McCarthy, J; Ott, VL; Rapraeger, AC; Reiland, J; Yeaman, C | 1 |
| Flint, AJ; Garton, AJ; Tonks, NK | 1 |
| Frey, T; Ledbetter, JA; Lund-Johansen, F; Thompson, PA | 1 |
| Clark, MR; Lee, YJ; Luisiri, P | 1 |
| Han, JD; Rubin, CS | 1 |
| Ballmer-Hofer, K; Meili, R | 1 |
| Aggarwal, BB; Darnay, BG; Singh, S | 1 |
| Bianchi, R; Eichberg, J; Iyer, S; Rowe-Rendleman, CL | 1 |
| Natarajan, V; Scribner, WM; Vepa, S | 1 |
| Fujimoto, S; Hayakawa, T; Kawakami, N; Shimohama, S; Sumida, Y | 1 |
| Austin, CD; Shields, D | 1 |
| Gresser, MJ; Huyer, G; Kelly, J; Kennedy, B; Liu, S; Moffat, J; Payette, P; Ramachandran, C; Tsaprailis, G | 1 |
| Chen, K; Cohen, S; Ruff, SJ | 1 |
| Caughman, SW; Duff, JL; Naik, SM; Paxton, LL; Quinlan, KL | 1 |
| Abdullah, N; Fantus, IG; Tsiani, E | 1 |
| Beauchemin, N; Chow, B; Daniels, E; Kunath, T; Robitaille, J; Turbide, C; Veillette, A | 1 |
| Llinás, R; Mohammadi, M; Moreno, H; Schlessinger, J; Sugimori, M | 1 |
| Halldórsson, H; Helgadóttir, A; Kjeld, M; Magnúsdóttir, K; Thorgeirsson, G | 1 |
| Hussein, B; Jakobs, KH; Keller, J; Rümenapp, U; Schmidt, M | 1 |
| Gebert, CA; Park, SH; Waxman, DJ | 3 |
| Ayalon, O; Geiger, B | 1 |
| Clairvoyant, F; Jallal, B; Knyazev, P; Mossie, K; Schilling, J; Ullrich, A; Vasiloudis, G; Zachwieja, J | 1 |
| Carpenter, G; Davidson, M; Guo, DF; Inagami, T; Xu, Y | 1 |
| Corbett, SA; Schwarzbauer, JE | 1 |
| Cortizo, AM; Etcheverry, SB; Sálice, VC; Vescina, CM | 1 |
| Catarsi, S; Drapeau, P | 1 |
| Aggarwal, BB; Darnay, BG | 1 |
| Freyermuth, S; Krady, MM; Malviya, AN; Rogue, P | 1 |
| Acuto, O; Bottomly, K; Farber, DL | 1 |
| Hershkoviz, R; Kachalsky, SG; Lider, O; Miron, S | 1 |
| Berg, LJ; Bunnell, SC; Heyeck, SD; Wilcox, HM | 1 |
| Aggarwal, BB; Dhawan, S; Singh, S | 1 |
| Altaratz, H; Cohen, J; Klingmüller, U; Neumann, D; Zick, Y | 1 |
| Berman, K; Dagan, D; Holmes, TC; Levitan, IB; Swartz, JE | 1 |
| Kramer, RH; Molokanova, E; Savchenko, A; Trivedi, B | 1 |
| Doroshenko, P | 1 |
| Choi, JL; Griffin, JD; Rohrschneider, LR; Salgia, R; Sattler, M; Shrikhande, G; Verma, S | 1 |
| Srivastava, AK; St-Louis, J | 1 |
| Ala, TA; Frey, WH; Venters, H | 1 |
| Briski, KP; Hosick, HL; McIntyre, BS; Sylvester, PW | 1 |
| Conus, NM; Hemmings, BA; Pearson, RB | 1 |
| Kemler, R; Ozawa, M | 1 |
| Choi, MU; Lee, SY; Yeo, EJ | 1 |
| Djiane, J; Edwards, GM; Hennighausen, L; Liu, X; Streuli, CH; Wilford, FH | 1 |
| Alava, MA; Bonvini, E; DeBell, KE; Graham, L; Laborda, J; Rellahan, BL; Stoica, B | 1 |
| Clowes, AW; Daum, G; Davies, MG; Kalmes, A; Levkau, B; Wang, Y | 1 |
| Davis-Amaral, EM; Goldstein, L; Leibowitz, KL; Musch, MW | 1 |
| Feick, P; Gilhaus, S; Schulz, I | 1 |
| Damour, O; Rousselle, P; Soler, C | 1 |
| Dai, Z; Peng, HB | 1 |
| Edwards, SW; Watson, F | 1 |
| Kindzelskii, AL; Minor, J; Moore, EC; Petty, HR; Shaya, S; Todd, RF | 1 |
| Brown, CL; Carpenter, G; Dempsey, PJ; Rudolph-Owen, LA; Vecchi, M | 1 |
| Akaike, N; Li, JS; Pang, ZP; Xu, TL | 1 |
| Blank, U; Blumberg, PM; Rivera, J; Song, JS; Swann, PG; Szallasi, Z | 1 |
| Fadool, DA; Levitan, IB | 1 |
| Blake, DJ; Davies, KE; Loh, NY; Nawrotzki, R; Ruegg, MA | 1 |
| Jumaa, H; Nielsen, PJ; Reth, M; Schweikert, J; Wienands, J; Wollscheid, B | 1 |
| Eichel-Streiber, CV; Jakobs, KH; Olesch, S; Ott, S; Rümenapp, U; Schmidt, M | 1 |
| Dupont, JL; Krady, MM; Malviya, AN | 1 |
| Bolander, FF | 1 |
| El-Shazly, A; Eura, M; Ishikawa, T; Masuyama, K; Samejima, Y | 1 |
| Kato, M; Kita, H; Morikawa, A; Tokuyama, K | 1 |
| Bogdanovic, E; Fantus, IG; Nagy, L; Sorisky, A; Tsiani, E | 1 |
| El-Mowafy, AM; White, RE | 1 |
| Dunah, AW; Wolfe, BB; Yasuda, RP | 1 |
| Ellenberg, J; Lippincott-Schwartz, J; Presley, J; Samelson, LE; Sloan-Lancaster, J; Yamazaki, T | 1 |
| Falet, H; Pain, S; Rendu, F | 1 |
| Daniels, KJ; Hay, ED; Kim, K | 1 |
| Furniss, MJ; Miller, SC | 1 |
| Hemmings, BA; Meier, R; Thelen, M | 1 |
| Reth, M; Wienands, J; Zhang, Y; Zürn, C | 1 |
| Fukunaga, T; Ishibashi, S; Nigorikawa, K; Okamura, N; Yaname, H | 1 |
| Baeuerle, PA; Béraud, C; Henzel, WJ | 1 |
| Celli, J; Finlay, BB; Goosney, DL; Kenny, B | 1 |
| Burns, CJ; Harris, TE; Jones, PM; Persaud, SJ | 1 |
| Barillas-Mury, C; Han, YS; Kafatos, FC; Seeley, D | 1 |
| Grgurevich, S; McVicar, DW; Mikhael, A | 1 |
| Cance, WG; Dy, RC; Earp, HS; Graves, LM; Li, X | 1 |
| Albanell, J; Arribas, J; Baselga, J; Codony-Servat, J; Lopez-Talavera, JC | 1 |
| Buckley, CD; Cody, AJ; Douglas, M; Freeman, SD; Simmons, DL; Taylor, VC | 1 |
| Burns, CJ; Howell, SL; Jones, PM; Persaud, SJ | 1 |
| Kwiatkowska, K; Sobota, A | 1 |
| Bird, IN; Bradfield, PF; Buckley, CD; Douglas, MR; Freeman, S; Lord, JM; Pumphrey, NJ; Salmon, M; Taylor, V; Wakelam, MJ; Young, SP | 1 |
| Buse, P; Firestone, GL; Hemmings, BA; Leong, ML; Maiyar, AC; Park, J | 1 |
| Feng, L; Liao, J; Omary, MB; Zhou, X | 1 |
| Lee, RS; Mukhopadhyay, NK; Narsimhan, RP; Neel, BG; Roberts, TM; Xia, K | 1 |
| Bonvini, E; Di Baldassarre, A; Di Valerio, V; Manzoli, FA; Miscia, S; Rana, RA; Sabatino, G; Vitale, M | 1 |
| Burakoff, SJ; Jin, YJ; Yu, CL | 1 |
| Dröge, W; Hehner, SP; Hofmann, TG; Schmitz, ML | 1 |
| Goldstein, BJ; Harada, S; Jarett, L; Smith, JA; Solow, BT; White, MF | 1 |
| Cornejo MacIel, F; Mendez, C; Paz, C; Podesta, EJ | 1 |
| El-Shazly, A; Ishikawa, T; Masuyama, K; Suda, T; Yamaguchi, N | 1 |
| Brown, MR; Riehle, MA | 1 |
| Klein, J; Kötter, K | 1 |
| Aoki, T; Fujimoto, T; Nomura, R | 1 |
| Blanchetot, C; Buist, A; den Hertog, J | 1 |
| Hemrika, W; Piersma, SR; Renirie, R; Wever, R | 1 |
| Atkinson, JP; Chan, AC; Liszewski, MK; Wang, G | 1 |
| Inoue, M; Kido, H; Mori, H; Wakabayashi, H; Yano, M | 1 |
| Hill, MA; Murphy, TV; Spurrell, BE | 3 |
| Sui, X; Xu, F; Xu, M; Zhao, R; Zhao, ZJ | 1 |
| Cruz, A; DeFouw, DO; DeFouw, LM | 1 |
| Brooks, SR; Carter, RH; Li, X; Volanakis, EJ | 1 |
| Bershadsky, AD; Elbaum, M; Gazit, A; Geiger, B; Levitzki, A; Volberg, T | 1 |
| Aggarwal, BB; Manna, SK; Mukhopadhyay, A | 1 |
| Buxbaum, JD; Corfas, G; Peschon, JJ; Rio, C | 1 |
| Agmon-Levin, N; Altevogt, P; Gutwein, P; Krauss, K; Mechtersheimer, S; Oleszewski, M | 1 |
| Cabral, CM; Choudhury, P; Liu, Y; Sifers, RN | 1 |
| Becker, KF; Candidus, S; Feller, S; Handschuh, G; Höfler, H; Hutzler, P; Luber, B; Mentele, E; Voss, J | 1 |
| Byrne, CH; Greenfield, EA; Griffin, JD; Pride, YB; Salgia, R; Sattler, M; Shrikhande, G; Verma, S; Winkler, T | 1 |
| Dröge, W; Hehner, SP; Hofmann, TG; Kaltschmidt, B; Kaltschmidt, C; Schmitz, ML | 1 |
| Asai, DJ; Faruki, S; Geahlen, RL | 1 |
| Dong, LQ; Hu, D; Langlais, P; Liu, F | 1 |
| Müller, R; Reth, M; Wienands, J | 1 |
| Carpenter, G; Zhou, W | 1 |
| Fujita, M; Uezato, T; Wu, YX | 1 |
| Liu, AY; Park, J | 1 |
| Castranova, V; Kang, JL; Lee, HS; Pack, IS | 1 |
| Bixby, JL; Bookman, RJ; Sun, QL; Wang, J | 1 |
| Frantz, JD; Lindholm, CK; Shoelson, SE; Welsh, M | 1 |
| Alon, R; Chen, LL; Feigelson, SW; Grabovsky, V; Lobb, R; Pepinsky, RB; Winter, E; Yablonski, D; Yednock, T | 1 |
| Claro, E; Ramos, B; Salido, G; Sarri, E | 1 |
| Xu, F; Zhao, ZJ | 1 |
| Camandola, S; Mattson, MP; Poli, G | 1 |
| Cao, X; Chen, G; Huang, X; Yu, Y; Yuan, Z; Zhang, M; Zhang, W | 1 |
| Abraham, RT; Busuttil, V; Imbert, V; Livolsi, A; Peyron, JF | 1 |
| Davis, B; Hu, MC; Ling, P; Meyer, CF; Redmond, LP; Rich, RR; Shui, JW; Tan, TH; Wange, RL | 1 |
| Arman, M; Gimferrer, I; Lozano, F; Padilla, O; Places, L; Simarro, M; Vilà, JM; Vives, J | 1 |
| Depetris, RS; Uchitel, OD; Urbano, FJ | 1 |
| Benes, C; Soltoff, SP | 1 |
| Kraas, JR; Mohamed, AS; Rivas-Plata, KA; Saleh, SM; Swope, SL | 1 |
| Anastasiadis, P; Böhmer, FD; Keilhack, H; Mariner, DJ; Reynolds, AB; Wang, J | 1 |
| Abrahamsen, H; Horejsí, V; Mustelin, T; Rolstad, B; Schraven, B; Taskén, K; Torgersen, KM; Vang, T; Yaqub, S | 1 |
| Heldin, CH; Ostman, A; Persson, C; Shimizu, A | 1 |
| Kim, K; Lee, KY | 1 |
| Avraham, H; Avraham, S; Fu, Y; Kaczmarek, E; Koziak, K; Park, SY | 1 |
| Cornejo Maciel, F; Gorostizaga, A; Paz, C; Poderoso, C; Podestá, EJ | 1 |
| Brazil, DP; Hemmings, BA; Hess, D; Hill, MM; Hofsteenge, J; Park, J | 1 |
| Chan, AC; Engels, N; Longnecker, R; Merchant, M; Pappu, R; Wienands, J | 1 |
| Elis, W; Gimborn, K; Huber, M; Leitges, M | 1 |
| Duschl, A; Haake, M; Stolzenberger, S | 1 |
| Aguado, B; Campbell, RD; de Vet, EC | 1 |
| MacKenzie, CJ; Paul, A; Plevin, R; Torrie, LJ | 1 |
| Creutz, CE; Eberhard, DA; Karns, LR; VandenBerg, SR | 1 |
| Chen, CJ; Kaplan, B; Schumann, D; Shively, JE | 1 |
| Brazil, DP; Galetic, I; Hemmings, BA; Ingley, E; Kaech, S; Maira, SM; Thelen, M | 1 |
| Balaian, L; Ball, ED | 1 |
| Barisone, I; Di Mauro, D; Fumagalli, G; Sala, C; Sava, A | 1 |
| Abramson, J; Fridkin, M; Pecht, I; Xu, R | 1 |
| Ahn, HY; Ha, KS; Hyun, MS; Kim, EG; Kim, HS; Min, DS; Shin, EY; Shin, JC; Shin, KS | 1 |
| Guerrah, A; Xu, F; Xu, MJ; Zeng, F; Zhao, R; Zhao, ZJ | 1 |
| Belevych, AE; Harvey, RD; Nulton-Persson, A; Sims, C | 1 |
| Ganesan, TS; L'hôte, CG; Thomas, PH | 1 |
| Ahn, BH; Chang, JS; Choi, JY; Chung, KC; Hahn, SJ; Jo, YH; Kim, MS; Kim, SY; Kwon, TK; Lee, MY; Lee, YH; Min, DS; Rhim, H; Sung, YM; Wolozin, B; Yoon, SH | 1 |
| Boulven, I; Desmyter, C; Harbon, S; Leiber, D; Robin, P | 1 |
| Andjelkovic, M; Hafen, E; Hemmings, BA; Laffargue, M; Oldham, S; Stocker, H; Wymann, MP | 1 |
| Burns, CJ; Gyles, SL; Jones, PM; Persaud, SJ; Sayed, SB; Squires, PE; Whitehouse, BJ | 1 |
| D'Adamio, L; Pelicci, G; Pelicci, PG; Roncarati, R; Tarr, PE | 1 |
| Aoto, H; Ishino, M; Sasaki, H; Sasaki, T | 1 |
| Kim, EG; Min, DS; Shin, EY | 1 |
| Dong, LQ; Guo, Z; Lim, MA; Liu, F; Ramos, FJ; Richardson, A; Strong, R; Wick, MJ | 1 |
| Gimborn, K; Huber, M; Pracht, C; Reth, M | 1 |
| Conus, NM; Cristiano, BE; Hannan, KM; Hemmings, BA; Pearson, RB | 1 |
| Kikawa, KD; Kinch, MS; Van Etten, RL; Vidale, DR | 1 |
| Cayabyab, FS; Schlichter, LC; Tsui, FW | 1 |
| Cantrell, DA; Costello, PS; Gallagher, M | 1 |
| Engelhardt, JF; Fan, C; Yang, J | 1 |
| Davis, AE; Liu, D; Prada, AE; Scafidi, J; Zahedi, K | 1 |
| Bernard, A; Deckert, M; Foucault, I; Liu, YC | 1 |
| Chérin, P; Courtois, H; Devulder, B; Dominique, S; Hachulla, E; Hatron, PY; Hellot, MF; Herson, S; Levesque, H; Marie, I | 1 |
| Dobashi, H; Ishida, H; Ishida, T; Kitanaka, A; Kubo, A; Kubota, Y; Matsumoto, A; Ohnishi, H; Tanaka, T; Tokuda, M; Waki, M | 1 |
| Döppler, H; Johannes, FJ; Storz, P; Toker, A | 1 |
| Cai, D; Dhe-Paganon, S; Lee, J; Melendez, PA; Shoelson, SE | 1 |
| Cha, HY; Hoe, KL; Hwang, BD; Kim, YR; Lim, K; Namgung, U; Park, SK | 1 |
| Bustelo, XR; Gutkind, JS; Marinissen, MJ; Servitja, JM; Sodhi, A | 1 |
| Aittomaki, S; Jänne, OA; Kotaja, N; Palvimo, JJ; Silvennoinen, O; Ungureanu, D; Vanhatupa, S; Yang, J | 1 |
| Ding, GR; Hirose, H; Honda, N; Miyakoshi, J; Nakahara, T; Tian, F; Yoshida, M | 1 |
| Band, H; Band, V; Druker, BJ; Duan, L; Miura-Shimura, Y; Rao, NL; Reddi, AL; Rottapel, R; Shimura, H; Tsygankov, A | 1 |
| Sheibani, N; Wu, J | 1 |
| Auger, R; Dreux, C; Le Gall, SM; Mauduit, P | 1 |
| Jäck, HM; Mielenz, D; Ruschel, A; Vettermann, C | 1 |
| Kundu, GC; Mahabeleshwar, GH | 1 |
| Krajewski, JL; Kramer, RH; Luetje, CW | 1 |
| Fallon, JR; Hoch, W; Hopf, C; Kirber, MT; Megeath, LJ | 1 |
| Galla, HJ; Krischke, M; Lohmann, C; Wegener, J | 1 |
| Arribas, J; López-Casillas, F; Velasco-Loyden, G | 1 |
| Aoyama, H; Ferreira, CV; Freire, AC; Haun, M | 1 |
| Brown, EJ; Chen, TT; Huang, EJ; Seaman, WE | 1 |
| De Blas, G; Mayorga, LS; Roggero, CM; Saling, PM; Tomes, CN | 1 |
| Namiki, H; Suzuki, K; Takahashi, H | 1 |
| den Hertog, J; Engström, U; Groen, A; Heldin, CH; Hellman, U; Kappert, K; Ostman, A; Persson, C; Sjöblom, T | 1 |
| Beauchemin, N; Obrink, B; Sundberg, U | 1 |
| Lindquist, M; Ponnappan, S; Ponnappan, U; Uken-Trebilcock, G | 1 |
| Brodsky, FM; Crotzer, VL; Mabardy, AS; Weiss, A | 1 |
| Bril, WS; de Ruiter, T; Lebbink, RJ; Meyaard, L; Verbrugge, A | 1 |
| Carson, DD; Thathiah, A | 1 |
| Brummer, T; Elis, W; Huber, M; Reth, M | 1 |
| Everill, B; Morielli, AD; Nesti, E | 1 |
| Chattopadhyay, S; Kinter, M; McCue, B; Sadhukhan, R; Santhamma, KR; Sen, I | 1 |
| Cron, P; Feng, J; Hemmings, BA; Hess, D; Park, J | 1 |
| Ikehara, SK; Ikehara, Y; Paulson, JC | 1 |
| den Hertog, J; Overvoorde, J; van der Wijk, T | 1 |
| Bertagnolli, MM; Carothers, AM; Hunt, DH; Javid, SH; Moran, AE; Redston, M | 1 |
| Radha, V; Rajanna, A; Swarup, G | 1 |
| Mancini, A; Niedenthal, R; Ohrt, T; Tamura, T | 1 |
| Bhat, GJ; Samikkannu, T; Thekkumkara, TJ; Thomas, JJ | 1 |
| Amiot, M; Bataille, R; Descamps, G; Pellat-Deceunynck, C; Robillard, N; Szpak, Y | 1 |
| Bellón, T; Kitzig, F; López-Botet, M; Martínez-Barriocanal, A; Sayós, J | 1 |
| Baumann, M; Frye, T; Gomez-Cambronero, J; Naqvi, T | 1 |
| Allebach, J; Brown, P; Chen, P; Kim, KT; Levis, M; Small, D | 1 |
| Lee, YM; Omary, MB; Salemi, MR; Strnad, P; Tao, GZ; Zhou, Q | 1 |
| Bertagnolli, MM; Carothers, AM; Moran, AE; Redston, M; Weyant, MJ | 1 |
| Madhavan, R; Peng, HB; Ruegg, MA; Zhao, XT | 1 |
| Dunah, AW; Hoogenraad, CC; Hueske, E; Jaworski, J; Liu, G; Pak, DT; Sheng, M; Simonetta, A; Wyszynski, M | 1 |
| Judah, JD; Lo, LC; Thomas, GM; Webb, RJ | 1 |
| Begum, S; Cope, AP; Peirce, MJ; Saklatvala, J; Wait, R | 1 |
| Bastiaens, PI; Hasenberg, T; Herzog, T; Keese, M; Magdeburg, RJ; Offterdinger, M; Pepperkok, R; Sturm, JW | 1 |
| Anderton, BH; Bird, IN; Brion, JP; Byers, HL; Derkinderen, P; Hanger, DP; Kellie, S; Lenz, C; Leroy, K; Leung, KY; Noble, W; Perera, T; Price, C; Reynolds, CH; Scales, TM; Van Etten, RA; Ward, MA; Williamson, R | 1 |
| Gross, S; Meurer, S; Müller-Esterl, W; Pioch, S | 1 |
| Bordin, L; Brunati, AM; Clari, G; Ion-Popa, F; Low, PS | 1 |
| Sheth, PR; Watowich, SJ | 1 |
| Courjault-Gautier, F; Felley-Bosco, E; Hausel, P; Latado, H | 1 |
| Chow, CW; Downey, GP; Herrera Abreu, MT; Hong, O; McCulloch, CA; Suzuki, T; Vachon, E; Villar, J; Wang, Q; Wang, Y | 1 |
| Mädler, HJ; Schnittler, HJ; Seebach, J; Wojciak-Stothard, B | 1 |
| Diestel, S; Hinkle, CL; Maness, PF; Schmitz, B | 1 |
| Huang, J; McNaughton, PA; Zhang, X | 1 |
| Frolkis, M; Gong, X; Ku, NO; Nakamichi, I; Omary, MB; Pytela, R; Tao, GZ; Wang, J; Zhu, W | 1 |
| Bastow, ER; Blenis, J; Lamb, KJ; Lewthwaite, JC; Pitsillides, AA; Wheeler-Jones, CP | 1 |
| Chariot, A; Charlier, E; Erneux, C; Gloire, G; Piette, J; Rahmouni, S; Volanti, C | 1 |
| Braunstein, I; Chemnitz, JM; Lanfranco, AR; Riley, JL | 1 |
| Zhang, Z; Zhao, XT | 1 |
| Aichem, A; Illges, H; Masilamani, M | 1 |
| Akaaboune, M; Bruneau, EG | 1 |
| Hovens, CM; I, ST; Lock, P; Schieb, H; Straffon, AF; Stylli, SS | 1 |
| Ozer, Z; Uckun, F; Vassilev, A | 1 |
| El Mjiyad, N; Gloire, G; Habraken, Y; Haegeman, G; Horion, J; Piette, J; Quivy, V; Van Lint, C; Vanden Berghe, W; Vermeulen, L | 1 |
| Chan, WC; Du, C; Ge, B; McKeithan, T; Pan, Z; Shen, Y | 1 |
| Boeri Erba, E; Bunkenborg, J; Cabodi, S; Defilippi, P; Di Stefano, P; Jensen, ON; Matthiesen, R; Schulze, WX; Tarone, G | 1 |
| Aoki, T; Hagiwara, H; Matsuzaki, T; Suzuki, T; Takata, K | 1 |
| Abdullah, LH; Davis, CW | 1 |
| Eichenberger, S; Gerber, B; Reusch, CE; Wittenbrink, MM | 1 |
| Dráber, P; Dráberová, L; Farghali, H; Heneberg, P; Smíd, F | 1 |
| Band, H; Cook, SJ; Wiggins, CM | 1 |
| Bonventre, JV; Humphreys, BD; Zhang, Z | 1 |
| Bernstein, ID; Cooper, JA; Häusermann, P; Kamikura, DM; Raden, BW; Teckchandani, AM; Walter, RB | 1 |
| Göbel, TW; Hanczaruk, MA; Schmitt, FC; Schmitt, R; Viertlboeck, BC | 1 |
| Bongarzone, I; Canevari, S; Fabbi, M; Ferrini, S; Mezzanzanica, D; Orengo, AM; Piazza, T; Puppo, A; Rossello, A; Rosso, O | 1 |
| Dráber, P; Dráberová, L; Korb, J; Lebduska, P; Smrz, D | 1 |
| Aichem, A; Hoefer, MM; Illges, H; Knight, AM | 1 |
| An, X; Cowburn, D; Cui, P; Debnath, AK; Guo, X; Hossain, S; Kotula, L; Warner, B; Xiong, X; Xu, R | 1 |
| D'Souza, S; Dean, W; Essick, E; Sithu, S | 1 |
| Crèvecoeur, J; Gloire, G; Merville, MP; Piette, J | 1 |
| Kajiho, H; Katada, T; Kontani, K; Minoda, T; Nakagawa, S; Sakurai, K; Yoshikawa, M | 1 |
| Bromberg, Y; Shani, V; Sperling, O; Zoref-Shani, E | 1 |
| Colin, Y; Genetet, S; Le Van Kim, C; Lopez, C; Métral, S; Ripoche, P; Sohet, F | 1 |
| Cora, EM; Maihle, NJ; Negron-Vega, L; Nieves-Alicea, R; Perez-Torres, M; Valle, BL | 1 |
| Brown, AC; Mawby, WJ; Toye, AM; Williamson, RC | 1 |
| Gnad, F; Mann, M; Olsen, JV; Pan, C | 1 |
| Deramaudt, TB; Hamadi, A; Rondé, P; Takeda, K | 1 |
| Fu, XW; Lindstrom, J; Spindel, ER | 1 |
| Frame, MC; Huang, H; Lu, S; Ouyang, M; Seong, J; Wang, Y; Zhang, J | 1 |
| González-Fernández, L; Macias-Garcia, B; Ortega-Ferrusola, C; Peña, FJ; Salido, GM; Tapia, JA | 1 |
| Holodick, NE; Rothstein, TL; Tumang, JR | 1 |
| Brazil, DP; Byun, HS; Cho, JY; Chun, T; Hemmings, BA; Hess, D; Hong, J; Hur, GM; Kim, JL; Kweon, GR; Li, Y; Maira, SM; Park, J; Park, KA; Piao, L; Sack, R; Seok, JH; Won, M; Yang, KJ | 1 |
| Hwang, SA; Jang, SH; Karnik, SS; Kim, M; Kim, MS; Lee, C; Yun, SH | 1 |
| Firaguay, G; Nunès, JA | 1 |
| Cullen, SJ; Ponnappan, S; Ponnappan, U | 1 |
| Enkavi, G; Feng, J; Gehrig, P; Lucchinetti, E; Roschitzki, B; Schaub, MC; Tajkhorshid, E; Wang, Y; Zaugg, K; Zaugg, M | 1 |
| Bambousková, M; Dráber, P; Dráberová, L; Heneberg, P; Pompach, P | 1 |
| Charron, G; Hang, HC; Raghavan, AS; Tsou, LK; Zhang, MM | 1 |
| Coulombe, G; Rivard, N; Simoneau, M; Vandal, G; Vézina, A | 1 |
| Johnson, KJ; Liu, C; Peck, AR; Rui, H; Schaber, JD; Sjolund, AB; Tran, TH; Utama, FE; Witkiewicz, AK | 1 |
| Dehio, C; Mistl, C; Quebatte, M; Scheidegger, F | 1 |
| Cui, JR; Ji, DB; Liu, JT; Ran, FX; Xu, B | 1 |
| Ahn, KS; Jeong, SJ; Kim, DH; Kim, M; Kim, SH; Lee, EO; Lee, HJ; Park, S; Song, HS | 1 |
| Gupta, V; Kalayarasan, S; Mitra, A; Radha, V | 1 |
| García-Ruiz, I; Gómez-Izquierdo, E; Muñoz-Yagüe, MT; Solís-Herruzo, JA; Solís-Muñoz, P; Valverde, AM | 1 |
| Bobrich, M; Brobeil, A; Tag, C; Wimmer, M | 1 |
| Biglia, N; Cassoni, P; Castellano, I; Daniele, L; Marchiò, C; Molinaro, L; Montemurro, F; Recupero, D; Righi, A; Risio, M; Sapino, A; Sismondi, P; Viale, G | 1 |
| Ferns, MJ; Rudell, JB | 1 |
| Boutterin, MC; Doly, S; Faure, C; Gervasi, N; Mazot, P; Tremblay, ML; Vigny, M | 1 |
| Canagarajah, BJ; Colon-Gonzalez, F; Gutierrez-Uzquiza, A; Hurley, JH; Kazanietz, MG; Leonard, TA; Mayer, BJ; Wang, H | 1 |
| Augustine, MM; Broadwater, M; Chen, J; Chen, L; Flies, SJ; Han, X; Iliopoulou, BP; Luo, L; Phennicie, RT; Ruff, W; Taube, JM; Xu, H; Yao, S; Zheng, L; Zhu, G; Zhu, Y | 1 |
| Acharya, C; Baty, CJ; Cline, R; Durgampudi, C; Husain, SZ; Karlsson, J; Mishra, V; Navina, S; Noel, P; Orlichenko, L; Patel, K; Singh, VP; Stolz, DB; Trivedi, RN | 1 |
| Allbritton, NL; Bair, E; Dailey, LA; Phillips, RM; Samet, JM | 1 |
| Caruso, JA; Caruthers, NJ; Dombkowski, A; Gill, R; Rosenspire, AJ; Stemmer, PM | 1 |
| Cullen, S; Ponnappan, S; Ponnappan, U | 1 |
| Heinzlmeir, S; Kuster, B; Lemeer, S; Médard, G; Ruprecht, B; Zecha, J | 1 |
| Bantscheff, M; Childs, D; Doce, C; Drewes, G; Eberhard, D; Franken, H; Huber, W; Reinhard, FB; Savitski, MF; Savitski, MM; Werner, T | 1 |
| Chiang, CY; Cho, CY; Huang, CY; Jeng, WY; Kan, WC; Lee, TH; Ling, P; Lu, TJ; Lu, TL; Weng, YP; Wu, JB | 1 |
| Ahn, KS; Baek, SH; Kim, C; Ko, JH; Lee, JH; Lee, SG; Sethi, G; Um, JY; Yang, WM | 1 |
| Di Paolo, JA; Jin, F; Kearney, BP; Ramanathan, S; Robeson, M; Shao, L; Sharma, S | 1 |
| Murphy, SP; Thakar, J; Van Twisk, D | 1 |
| Babichev, Y; Dong, G; Gelkop, S; Isakov, N; Kalifa, R; Nath, PR | 1 |
| Daniwijaya, EW; Kitamura, Y; Kotani, T; Kusakari, S; Mantilidewi, KI; Matozaki, T; Murata, Y; Ohnishi, H; Okazawa, H | 1 |
| Carruthers, N; Caruso, JA; Gill, R; Rosenspire, A; Shin, N; Stemmer, PM | 1 |
| Hodges, PW; Jull, GA; Karayannis, NV; Nicholas, MK | 1 |
| Aballo, T; Chua, XY; Edmondson, RD; Mackintosh, SG; Mensah, T; Salomon, AR | 1 |
| Anrather, D; Ellmeier, W; Frohner, IE; Hartl, M; Mudrak, I; Ogris, E; Preglej, T; Schüchner, S; Sontag, E; Sontag, JM; Wadzinski, BE | 1 |
| Gao, S; He, X; Huang, M; Hui, E; Jing, R; Li, H; Masubuchi, T; Meng, L; Shi, X; Sun, J; Wang, H; Wong, CC; Wu, W; Xu, C; Xu, X; Zhang, N; Zhou, Q; Zhu, H | 1 |
1 review(s) available for vanadates and pervanadate
| Article | Year |
|---|---|
Smooth muscle contractility and protein tyrosine phosphorylation.
Topics: Animals; Calcium; Enzyme Inhibitors; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Swine; Vanadates | 1997 |
1 trial(s) available for vanadates and pervanadate
| Article | Year |
|---|---|
Pharmacokinetics, Pharmacodynamics, and Safety of Entospletinib, a Novel pSYK Inhibitor, Following Single and Multiple Oral Dosing in Healthy Volunteers.
Topics: Adolescent; Adult; B-Lymphocytes; Basophils; Cohort Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Food-Drug Interactions; Healthy Volunteers; Humans; Male; Middle Aged; Syk Kinase; Tetraspanin 30; Vanadates; Young Adult | 2017 |
357 other study(ies) available for vanadates and pervanadate
| Article | Year |
|---|---|
Activation of signal transduction in platelets by the tyrosine phosphatase inhibitor pervanadate (vanadyl hydroperoxide).
Topics: Actins; Adenosine Triphosphate; Alkaloids; Blood Proteins; Blotting, Western; Calcium; Catechols; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Nitriles; Phospholipids; Phosphoproteins; Phosphorylation; Platelet Membrane Glycoproteins; Protein Kinase C; Protein Tyrosine Phosphatases; Serotonin; Signal Transduction; Staurosporine; Tetradecanoylphorbol Acetate; Type C Phospholipases; Tyrosine; Tyrphostins; Vanadates | 1992 |
Respiratory burst and tyrosine phosphorylation by vanadate.
Topics: Alkaloids; Animals; Cell Membrane; Cells, Cultured; Enzyme Inhibitors; Female; Guinea Pigs; Membrane Proteins; Phosphoproteins; Phosphotyrosine; Protein Kinase C; Respiratory Burst; Signal Transduction; Staurosporine; Superoxides; Vanadates | 1995 |
Tyrosine kinase-dependent assembly of actin plaques linking Fc epsilon R1 cross-linking to increased cell substrate adhesion in RBL-2H3 tumor mast cells.
Topics: Actins; Animals; Antigens; Cell Adhesion; Mast Cells; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Tyrosine phosphorylation of P-selectin in intact platelets and in a disulphide-linked complex with immunoprecipitated pp60c-src.
Topics: Blood Platelets; Disulfides; Humans; In Vitro Techniques; P-Selectin; Phosphorylation; Platelet Membrane Glycoproteins; Precipitin Tests; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Tyrosine; Vanadates | 1994 |
Stimulatory effect of pervanadate on calcium signals and histamine secretion of RBL-2H3 cells.
Topics: Animals; Calcium; Catalase; Histamine Release; Hydrogen Peroxide; Inositol 1,4,5-Trisphosphate; Leukemia, Basophilic, Acute; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Inhibition of phospholipase D of human platelets by protein tyrosine kinase inhibitors.
Topics: Amino Acid Sequence; Blood Platelets; Catechols; Cinnamates; Enzyme Activation; Genistein; GTP-Binding Proteins; Humans; In Vitro Techniques; Isoflavones; Molecular Sequence Data; Nitriles; Peptides; Phospholipase D; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Signal Transduction; Styrenes; Substrate Specificity; Thrombin; Tyrphostins; Vanadates | 1994 |
Regulation of vascular and gastric smooth muscle contractility by pervanadate.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Blotting, Western; Calcium; Epidermal Growth Factor; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Sodium; Stomach; Tyrosine; Vanadates | 1994 |
Magnesium-dependent stimulation of protein synthesis by the insulin mimic, pervanadate.
Topics: Animals; Biological Transport; Calcium; Cations, Divalent; Growth Hormone; Hexoses; Insulin; Ion Channels; Magnesium; Membrane Proteins; Oocytes; Signal Transduction; Vanadates; Xenopus laevis; Zinc | 1995 |
Functional link between phosphorylation state of membrane proteins and morphological changes of human erythrocytes.
Topics: Anion Exchange Protein 1, Erythrocyte; Erythrocyte Membrane; Ethers, Cyclic; Humans; Membrane Proteins; Microscopy, Electron, Scanning; Okadaic Acid; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Spectrin; Tyrosine; Vanadates | 1995 |
Ligand-dependent and -independent activation of the transcription factor gamma RF-1 in a cell-free system.
Topics: Adenosine Triphosphate; Antibodies; Base Sequence; Carcinoma, Squamous Cell; Cell Line; Cell-Free System; Cytosol; Humans; Interferon-gamma; Kinetics; Leukemia, Myeloid; Ligands; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Repetitive Sequences, Nucleic Acid; Skin Neoplasms; Transcription Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
The mitogen-activated protein kinase cascade in rat islets of Langerhans.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Ethers, Cyclic; Glucose; Islets of Langerhans; Isoenzymes; Mitogen-Activated Protein Kinase 1; Okadaic Acid; Phosphorylation; Phosphotyrosine; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
Immobilization of nicotinic acetylcholine receptors in mouse C2 myotubes by agrin-induced protein tyrosine phosphorylation.
Topics: Agrin; Animals; Cell Line; Fluorescence; Mice; Muscle, Skeletal; Phosphorylation; Rats; Receptor Aggregation; Receptors, Nicotinic; Tyrosine; Vanadates | 1995 |
Combination of insulinomimetic agents H2O2 and vanadate enhances insulin receptor mediated tyrosine phosphorylation of IRS-1 leading to IRS-1 association with the phosphatidylinositol 3-kinase.
Topics: Animals; CHO Cells; Cricetinae; Hydrogen Peroxide; Insulin; Insulin Receptor Substrate Proteins; Mutation; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Protein Tyrosine Phosphatases; Receptor, Insulin; Tyrosine; Vanadates | 1995 |
Tyrosine phosphorylation is required for eosinophil degranulation induced by immobilized immunoglobulins.
Topics: Cell Degranulation; Eosinophils; Genistein; Humans; Immunoglobulin E; Immunoglobulins; Inositol Phosphates; Isoflavones; Pertussis Toxin; Phosphatidylinositols; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Vanadates; Virulence Factors, Bordetella | 1995 |
A soluble protein negatively regulates phospholipase D activity. Partial purification and characterization.
Topics: Animals; Brain; Cattle; Cell Line; Cytosol; Enzyme Activation; Guanine Nucleotides; Humans; Kinetics; Membrane Lipids; Nerve Tissue Proteins; Phosphatidylinositols; Phospholipase D; Tetradecanoylphorbol Acetate; Vanadates | 1995 |
Tyrosine phosphatase antagonist-induced activation of the neutrophil NADPH oxidase: a possible role for protein kinase C.
Topics: Animals; Dose-Response Relationship, Drug; Hydroquinones; NADH, NADPH Oxidoreductases; NADPH Oxidases; Neutrophil Activation; Neutrophils; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Respiratory Burst; Superoxides; Vanadates | 1995 |
Receptor protein tyrosine phosphatase PTPmu associates with cadherins and catenins in vivo.
Topics: alpha Catenin; Animals; beta Catenin; Binding Sites; Brain; Cadherins; Cell Line; Cytoskeletal Proteins; Immunoblotting; Immunohistochemistry; Intercellular Junctions; Lung; Membrane Proteins; Mink; Myocardium; Phosphorylation; Precipitin Tests; Protein Binding; Protein Tyrosine Phosphatases; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Receptors, Cell Surface; Tissue Distribution; Trans-Activators; Vanadates | 1995 |
An SH3-binding site conserved in Bruton's tyrosine kinase and related tyrosine kinases mediates specific protein interactions in vitro and in vivo.
Topics: Agammaglobulinaemia Tyrosine Kinase; Amino Acid Sequence; Animals; Antibodies; B-Lymphocytes; Binding Sites; Cell Line; Chloramphenicol O-Acetyltransferase; Cloning, Molecular; Conserved Sequence; DNA Primers; Glutathione Transferase; Humans; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Oligopeptides; Point Mutation; Polymerase Chain Reaction; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Spleen; Transfection; Vanadates | 1995 |
Activation of STAT factors by prolactin, interferon-gamma, growth hormones, and a tyrosine phosphatase inhibitor in rabbit primary mammary epithelial cells.
Topics: Animals; Base Sequence; Biological Transport; Caseins; Cells, Cultured; DNA; DNA-Binding Proteins; Down-Regulation; Epidermal Growth Factor; Extracellular Matrix; Female; Glucocorticoids; Growth Hormone; Immune Sera; Interferon-gamma; Mammary Glands, Animal; Milk Proteins; Molecular Sequence Data; Pregnancy; Prolactin; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rabbits; RNA, Messenger; STAT1 Transcription Factor; STAT5 Transcription Factor; Trans-Activators; Vanadates | 1995 |
Tyrosine phosphorylation-dependent stimulation of amyloid precursor protein secretion by the m3 muscarinic acetylcholine receptor.
Topics: Alkaloids; Amyloid; Carbachol; Cell Line; Genistein; Humans; Isoflavones; Phosphorylation; Prion Proteins; Prions; Protein Kinase Inhibitors; Protein Precursors; Protein Tyrosine Phosphatases; Receptors, Muscarinic; Staurosporine; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 1995 |
Protein-tyrosine phosphatase inhibitors block tumor necrosis factor-dependent activation of the nuclear transcription factor NF-kappa B.
Topics: Adenosine Triphosphate; Arsenicals; Base Sequence; Ceramides; Diamide; DNA-Binding Proteins; Dose-Response Relationship, Drug; Ethers, Cyclic; Humans; I-kappa B Proteins; In Vitro Techniques; Interleukin-1; Marine Toxins; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Okadaic Acid; Oligodeoxyribonucleotides; Oxazoles; Protein Tyrosine Phosphatases; Signal Transduction; Tetradecanoylphorbol Acetate; Time Factors; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Vanadates | 1995 |
Structural requirements for inducible shedding of the p55 tumor necrosis factor receptor.
Topics: Amino Acids; Cells, Cultured; DNA Mutational Analysis; ErbB Receptors; Humans; Mutagenesis, Site-Directed; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Structure-Activity Relationship; Tetradecanoylphorbol Acetate; Vanadates | 1994 |
Activation of phospholipase C gamma in Schizosaccharomyces pombe by coexpression of receptor or nonreceptor tyrosine kinases.
Topics: Animals; Calcium; Cloning, Molecular; Enzyme Activation; Gene Expression; Isoenzymes; Kinetics; Mice; Phosphatidylinositols; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Mas; Rats; Receptor Protein-Tyrosine Kinases; Receptor, Platelet-Derived Growth Factor beta; Receptors, Platelet-Derived Growth Factor; Recombinant Proteins; Schizosaccharomyces; Substrate Specificity; Type C Phospholipases; Vanadates | 1995 |
The roles of multiple pathways in regulating bombesin-stimulated phospholipase D activity in Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Bombesin; Genistein; Glycerophospholipids; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Indoles; Isoflavones; Kinetics; Mice; Phosphatidic Acids; Phospholipase D; Protein Kinase C; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Vanadates | 1995 |
Rapid activation of the interferon-gamma signal transduction pathway by inhibitors of tyrosine phosphatases.
Topics: Base Sequence; DNA-Binding Proteins; Humans; Interferon-gamma; Molecular Sequence Data; Phosphorylation; Protein Tyrosine Phosphatases; Signal Transduction; STAT1 Transcription Factor; Time Factors; Trans-Activators; Transcription, Genetic; Tumor Cells, Cultured; Vanadates | 1994 |
Bi-directional control of smooth muscle tension: regulation by tyrosine kinase and tyrosine phosphatase.
Topics: Animals; Aorta, Thoracic; Blotting, Western; Densitometry; Genistein; In Vitro Techniques; Isoflavones; Muscle Contraction; Muscle, Smooth; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Stomach; Vanadates | 1994 |
Activation of multiple pH-regulatory pathways in granulocytes by a phosphotyrosine phosphatase antagonist.
Topics: Culture Media; Enzyme Activation; Fluorescent Dyes; Granulocytes; Humans; Hydrogen-Ion Concentration; NADH, NADPH Oxidoreductases; NADPH Oxidases; Onium Compounds; Protein Tyrosine Phosphatases; Proton-Translocating ATPases; Sodium; Sodium-Hydrogen Exchangers; Tumor Cells, Cultured; Vacuoles; Vanadates; Zinc | 1994 |
Pervanadate simulates the effects of interleukin-2 (IL-2) in human T cells and provides evidence for the activation of two distinct tyrosine kinase pathways by IL-2.
Topics: Cell Division; Cells, Cultured; Humans; In Vitro Techniques; Interferon-gamma; Interleukin-2; Janus Kinase 3; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Weight; Phosphoproteins; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Receptor Protein-Tyrosine Kinases; Signal Transduction; T-Lymphocytes; Vanadates | 1994 |
A dynamic system for suppression and re-expression of insulin and pervanadate bioresponses in rat adipocytes. Treatment with okadaic acid and staurosporine.
Topics: Adipose Tissue; Alkaloids; Animals; Drug Interactions; Ethers, Cyclic; Gene Expression Regulation; Insulin; Lipolysis; Male; Okadaic Acid; Phosphoprotein Phosphatases; Protein Phosphatase 1; Rats; Rats, Wistar; Staurosporine; Vanadates | 1994 |
Phosphatase inhibitors, gap junctional intercellular communication and [125I]-EGF binding in hamster fibroblasts.
Topics: Aluminum Compounds; Animals; Cell Communication; Cell Line; Connexin 43; Cricetinae; Cricetulus; Embryo, Mammalian; Epidermal Growth Factor; Ethers, Cyclic; Fibroblasts; Fluorides; Intercellular Junctions; Iodine Radioisotopes; Kinetics; Lung; Marine Toxins; Mesocricetus; Okadaic Acid; Oxazoles; Phosphoprotein Phosphatases; Tetradecanoylphorbol Acetate; Vanadates; Vanadium Compounds | 1993 |
The protein tyrosine phosphatase inhibitor, pervanadate, is a powerful antidiabetic agent in streptozotocin-treated diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Injections, Intraperitoneal; Male; Osmolar Concentration; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Time Factors; Vanadates | 1994 |
The phosphotyrosine phosphatase inhibitor vanadyl hydroperoxide induces morphological alterations, cytoskeletal rearrangements and increased adhesiveness in rat neutrophil leucocytes.
Topics: Actins; Animals; Blotting, Western; Cell Adhesion; Cell Movement; Cell Size; Cytoskeleton; In Vitro Techniques; Kinetics; Microscopy, Fluorescence; Neutrophils; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Vanadates | 1993 |
Complex formation between the p21ras GTPase-activating protein and phosphoproteins p62 and p190 is independent of p21ras signalling.
Topics: 3T3 Cells; Animals; Cell Line, Transformed; DNA-Binding Proteins; GTPase-Activating Proteins; Guanine Nucleotide Exchange Factors; Mice; Mitogen-Activated Protein Kinase 1; Nuclear Proteins; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proteins; Proto-Oncogene Proteins p21(ras); ras GTPase-Activating Proteins; ras-GRF1; Repressor Proteins; Signal Transduction; Transcription Factor TFIIH; Transcription Factors, TFII; Vanadates | 1993 |
Stimulatory effects of the protein tyrosine phosphatase inhibitor, pervanadate, on T-cell activation events.
Topics: Catalysis; Humans; Hydrolysis; Interleukin-2; Leukocyte Common Antigens; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Peptide Mapping; Phosphatidylinositols; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Signal Transduction; T-Lymphocytes; Tumor Cells, Cultured; Type C Phospholipases; Vanadates | 1993 |
Mechanism of pervanadate stimulation and potentiation of insulin-activated glucose transport in rat adipocytes: dissociation from vanadate effect.
Topics: Adipose Tissue; Animals; Biological Transport; Cells, Cultured; Drug Synergism; Glucose; Insulin; Phosphorylation; Protein Tyrosine Phosphatases; Quercetin; Rats; Receptor, Insulin; Vanadates | 1993 |
Cytosolic [Ca2+] homeostasis and tyrosine phosphorylation of phospholipase C gamma 2 in HL60 granulocytes.
Topics: Amino Acid Sequence; Biological Transport; Calcium; Calcium-Transporting ATPases; Cytosol; Homeostasis; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Kinetics; Leukemia, Promyelocytic, Acute; Manganese; Molecular Sequence Data; N-Formylmethionine Leucyl-Phenylalanine; Phosphorylation; Terpenes; Thapsigargin; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 1993 |
Human T lymphocyte activation induces tyrosine phosphorylation of alpha-tubulin and its association with the SH2 domain of the p59fyn protein tyrosine kinase.
Topics: Amino Acid Sequence; Humans; Leukemia, T-Cell; Lymphocyte Activation; Lymphoma, T-Cell; Molecular Sequence Data; Phosphoric Monoester Hydrolases; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; src Homology Domains; T-Lymphocytes; Tubulin; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Association of CD45 with Lck and components of the Ras signalling pathway in pervanadate-treated mouse T-cell lines.
Topics: Animals; Cell Line; Enzyme Inhibitors; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Phosphorylation; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins p21(ras); Rats; src Homology Domains; src-Family Kinases; T-Lymphocytes; Tyrosine; Vanadates | 1996 |
Regulation of single Cl- channel conductance by insulin and tyrosine phosphatase.
Topics: Animals; Calcium; Cell Line; Chloride Channels; Cytosol; Enzyme Inhibitors; Epithelium; Insulin; Kinetics; Membrane Potentials; Nephrons; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins pp60(c-src); Vanadates | 1996 |
Differential role of protein tyrosine phosphorylation/dephosphorylation in affinity regulation of beta 1 and beta 3 integrin in human fibroblasts.
Topics: Antibodies, Monoclonal; Antigens, CD; Arsenicals; Cell Adhesion; Enzyme Inhibitors; Fibroblasts; Humans; Integrin beta1; Integrin beta3; Integrins; Phosphorylation; Platelet Membrane Glycoproteins; Tyrosine; Vanadates | 1995 |
Activation of mitogen-activated protein (MAP) kinase pathway by pervanadate, a potent inhibitor of tyrosine phosphatases.
Topics: Calcium-Calmodulin-Dependent Protein Kinases; Dose-Response Relationship, Drug; Enzyme Activation; HeLa Cells; Humans; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatases; Time Factors; Vanadates | 1996 |
Phenylarsine oxide and vanadate: apparent paradox of inhibition of protein phosphotyrosine phosphatases in rat adipocytes.
Topics: 3-O-Methylglucose; Adipocytes; Animals; Arsenicals; Cells, Cultured; Enzyme Inhibitors; Epididymis; Ethers, Cyclic; Glycerol; Glycolysis; Insulin; Isoproterenol; Kinetics; Lipolysis; Male; Methylglucosides; Okadaic Acid; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Vanadates | 1996 |
Pervanadate mediated an increased generation of inositol phosphates and tension in rat myometrium. Activation and phosphorylation of phospholipase C-gamma 1.
Topics: Animals; Blotting, Western; Enzyme Inhibitors; Female; Genistein; Inositol Phosphates; Isoenzymes; Isoflavones; Myometrium; Nitriles; Phenols; Phospholipase C gamma; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Type C Phospholipases; Tyrosine; Tyrphostins; Uterine Contraction; Vanadates | 1996 |
Stimulation of the T-cell antigen receptor-CD3 complex signaling pathway by the tyrosine phosphatase inhibitor pervanadate is mediated by inhibition of CD45: evidence for two interconnected Lck/Fyn- or zap-70-dependent signaling pathways.
Topics: Base Sequence; Binding Sites; CD3 Complex; DNA; Enzyme Inhibitors; Humans; Interleukin-2; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Promoter Regions, Genetic; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Signal Transduction; src-Family Kinases; T-Lymphocytes; Transcription Factors; Tumor Cells, Cultured; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 1996 |
Evidence for a preformed transducer complex organized by the B cell antigen receptor.
Topics: Animals; Cell Line; Enzyme Inhibitors; Glycosylphosphatidylinositols; Hydrogen Peroxide; Immunoglobulin D; Immunoglobulin M; Kinetics; Multiple Myeloma; Phosphoproteins; Phosphorylation; Point Mutation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Recombinant Proteins; Signal Transduction; Vanadates | 1996 |
Role for protein phosphatase in the regulation of Ca2+ influx in parotid gland acinar cells.
Topics: Animals; Calcium; Carbachol; Enzyme Inhibitors; Male; Manganese; Marine Toxins; Okadaic Acid; Oxazoles; Parotid Gland; Phosphoprotein Phosphatases; Protein Kinase Inhibitors; Rats; Rats, Wistar; Stimulation, Chemical; Thapsigargin; Vanadates | 1996 |
A characterization of pervanadate, an inducer of cellular tyrosine phosphorylation and inhibitor of gap junctional intercellular communication.
Topics: Animals; Cell Communication; Cricetinae; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Embryo, Mammalian; Enzyme Inhibitors; Gap Junctions; Mesocricetus; Phosphorylation; Protein Tyrosine Phosphatases; Spectrophotometry, Ultraviolet; Vanadates; Vanadium Compounds | 1996 |
Tyrosine phosphorylation of the Kv1.3 potassium channel.
Topics: Animals; Cattle; Cell Line; ErbB Receptors; Humans; Mutation; Patch-Clamp Techniques; Phosphorylation; Phosphotransferases; Potassium Channel Blockers; Potassium Channels; Protein Tyrosine Phosphatases; Transfection; Tyrosine; Vanadates | 1996 |
A spatial gradient of tau protein phosphorylation in nascent axons.
Topics: Animals; Axons; Calibration; Cells, Cultured; Epitopes; Fluorescent Antibody Technique; Hippocampus; Immunoblotting; Microscopy, Fluorescence; Neurons; Phosphorylation; Protein Tyrosine Phosphatases; Rats; tau Proteins; Tissue Distribution; Vanadates | 1996 |
Tyrosine phosphorylation of I kappa B-alpha activates NF-kappa B without proteolytic degradation of I kappa B-alpha.
Topics: Alkaloids; Base Sequence; Calcimycin; Cell Hypoxia; DNA; DNA-Binding Proteins; Enzyme Inhibitors; Genistein; Humans; I-kappa B Proteins; Ionophores; Isoflavones; Leukocyte Common Antigens; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Binding; Protein Kinase C; Protein Tyrosine Phosphatases; src-Family Kinases; Staurosporine; T-Lymphocytes; Tetradecanoylphorbol Acetate; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Age-related tyrosine-specific protein phosphorylation defect in human T lymphocytes activated through CD3, CD4, CD8 or the IL-2 receptor.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antigens, CD; Benzoquinones; Blood Donors; CD3 Complex; CD4 Antigens; Enzyme Inhibitors; Humans; Lactams, Macrocyclic; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Receptors, Interleukin-2; Rifabutin; T-Lymphocytes; Vanadates | 1996 |
Regulation of the association of p120cbl with Grb2 in Jurkat T cells.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Electrophoresis, Polyacrylamide Gel; GRB2 Adaptor Protein; Humans; Jurkat Cells; Kinetics; Molecular Sequence Data; Muromonab-CD3; Mutagenesis, Site-Directed; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptors, Antigen, T-Cell; Recombinant Fusion Proteins; Structure-Activity Relationship; T-Lymphocytes; Ubiquitin-Protein Ligases; Vanadates | 1996 |
Pervanadate stimulation of wortmannin-sensitive and -resistant 2-deoxyglucose transport in adipocytes.
Topics: 3T3 Cells; Adipocytes; Androstadienes; Animals; Biological Transport; Cells, Cultured; Cinnamates; Deoxyglucose; Dose-Response Relationship, Drug; Enzyme Inhibitors; Insulin; Mice; Sulfides; Vanadates; Wortmannin | 1996 |
Pervanadate activation of intracellular kinases leads to tyrosine phosphorylation and shedding of syndecan-1.
Topics: Animals; Cell Line; Electrophoresis, Polyacrylamide Gel; Hydrogen Peroxide; Membrane Glycoproteins; Mice; Phosphorylation; Protein Kinases; Protein Tyrosine Phosphatases; Proteoglycans; Syndecan-1; Syndecans; Transfection; Tyrosine; Vanadates | 1996 |
Identification of p130(cas) as a substrate for the cytosolic protein tyrosine phosphatase PTP-PEST.
Topics: Animals; COS Cells; Crk-Associated Substrate Protein; Cytosol; Enzyme Inhibitors; HeLa Cells; Humans; Kinetics; Mammals; Mutagenesis, Site-Directed; Phosphoproteins; Point Mutation; Protein Tyrosine Phosphatase, Non-Receptor Type 12; Protein Tyrosine Phosphatases; Proteins; Recombinant Proteins; Retinoblastoma Protein; Retinoblastoma-Like Protein p130; Substrate Specificity; Transfection; Tumor Cells, Cultured; Vanadates | 1996 |
Apoptosis in hematopoietic cells is associated with an extensive decrease in cellular phosphotyrosine content that can be inhibited by the tyrosine phosphatase antagonist pervanadate.
Topics: Animals; Apoptosis; Blood Cells; Dexamethasone; Dose-Response Relationship, Drug; Enzyme Inhibitors; Etoposide; Flow Cytometry; Hematopoiesis; Humans; In Vitro Techniques; Mice; Phosphotyrosine; Protein Tyrosine Phosphatases; Thymus Gland; Tumor Cells, Cultured; Vanadates | 1996 |
A novel complex, p40/42, is constitutively associated with the B cell antigen receptor and phosphorylated upon receptor stimulation.
Topics: Animals; Antigens, CD; B-Lymphocytes; CD79 Antigens; Dimerization; Macromolecular Substances; Membrane Glycoproteins; Mice; Phosphorylation; Protein Processing, Post-Translational; Receptors, Antigen, B-Cell; Receptors, Platelet-Derived Growth Factor; Recombinant Fusion Proteins; Signal Transduction; Vanadates | 1996 |
Regulation of cytoskeleton organization and paxillin dephosphorylation by cAMP. Studies on murine Y1 adrenal cells.
Topics: Actins; Adrenal Cortex Neoplasms; Animals; Cell Adhesion Molecules; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Cytoskeleton; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Isoflavones; Mice; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Tyrosine; Vanadates | 1996 |
Activation-independent nuclear translocation of mitogen activated protein kinase ERK1 mediated by thiol-modifying chemicals.
Topics: Animals; Arsenicals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cell Nucleus; Enzyme Activation; Ethylmaleimide; Fluorescent Antibody Technique, Indirect; Microtubules; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Platelet-Derived Growth Factor; Protein Tyrosine Phosphatases; Rats; S Phase; Sulfhydryl Reagents; Tubulin; Tyrosine; Vanadates | 1996 |
Site-specific tyrosine phosphorylation of IkappaBalpha negatively regulates its inducible phosphorylation and degradation.
Topics: Amino Acid Sequence; Blotting, Western; DNA-Binding Proteins; Enzyme Induction; Enzyme Inhibitors; HeLa Cells; Humans; I-kappa B Proteins; Molecular Sequence Data; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Tyrosine Phosphatases; Structure-Activity Relationship; Tumor Cells, Cultured; Tyrosine; Vanadates | 1996 |
Tyrosine phosphorylation of myelin protein PO.
Topics: Animals; Hydrolysis; Male; Myelin P0 Protein; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Vanadates | 1996 |
Activation of protein phosphorylation by oxidants in vascular endothelial cells: identification of tyrosine phosphorylation of caveolin.
Topics: Animals; Cattle; Caveolin 1; Caveolins; Cells, Cultured; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Hydrogen Peroxide; Membrane Proteins; Oxidants; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Pulmonary Artery; Vanadates | 1997 |
Tyrosine phosphorylation and translocation of phospholipase C-gamma 2 in polymorphonuclear leukocytes treated with pervanadate.
Topics: Animals; Biological Transport; Cell Membrane; Cytosol; Female; Guinea Pigs; Isoenzymes; Monocytes; Phospholipase C gamma; Phosphorylation; Superoxides; Type C Phospholipases; Tyrosine; Vanadates | 1996 |
Formation of nascent secretory vesicles from the trans-Golgi network of endocrine cells is inhibited by tyrosine kinase and phosphatase inhibitors.
Topics: ADP-Ribosylation Factor 1; ADP-Ribosylation Factors; Amino Acid Sequence; Animals; Enzyme Inhibitors; Golgi Apparatus; GTP-Binding Proteins; Humans; Membrane Proteins; Molecular Sequence Data; Nitriles; Phosphorylation; Phosphotyrosine; Pituitary Gland; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Tyrosine; Tyrphostins; Vanadates; Zinc | 1996 |
Mechanism of inhibition of protein-tyrosine phosphatases by vanadate and pervanadate.
Topics: Animals; Edetic Acid; Enzyme Inhibitors; Hydrogen Peroxide; Kinetics; Mass Spectrometry; Protein Tyrosine Phosphatases; Vanadates | 1997 |
Peroxovanadate induces tyrosine phosphorylation of multiple signaling proteins in mouse liver and kidney.
Topics: Animals; DNA-Binding Proteins; Enzyme Inhibitors; Epidermal Growth Factor; Injections, Intraperitoneal; Kidney; Liver; Mice; Molecular Weight; Phosphorylation; Protein Sorting Signals; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; STAT1 Transcription Factor; Trans-Activators; Tyrosine; Vanadates | 1997 |
Pervanadate mimics IFNgamma-mediated induction of ICAM-1 expression via activation of STAT proteins.
Topics: DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression; Humans; Intercellular Adhesion Molecule-1; Interferon-gamma; Keratinocytes; Membrane Proteins; Protein Tyrosine Phosphatases; RNA, Messenger; Signal Transduction; STAT1 Transcription Factor; Trans-Activators; Tumor Cells, Cultured; Vanadates | 1997 |
Insulin-mimetic agents vanadate and pervanadate stimulate glucose but inhibit amino acid uptake.
Topics: Amino Acids; Animals; beta-Alanine; Carcinoma, Hepatocellular; Cell Line; Cycloheximide; Deoxyglucose; Drug Combinations; Enzyme Inhibitors; Glucose; Hypoglycemic Agents; Insulin; Muscle, Skeletal; Ouabain; Protein Tyrosine Phosphatases; Rats; Vanadates | 1997 |
Association of biliary glycoprotein with protein tyrosine phosphatase SHP-1 in malignant colon epithelial cells.
Topics: Amino Acid Sequence; Animals; Carcinoembryonic Antigen; Cell Adhesion Molecules; Colonic Neoplasms; Glycoproteins; Intracellular Signaling Peptides and Proteins; Mice; Molecular Sequence Data; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Tumor Cells, Cultured; Tyrosine; Vanadates | 1997 |
Differential pre- and postsynaptic modulation of chemical transmission in the squid giant synapse by tyrosine phosphorylation.
Topics: Animals; Calcium; Decapodiformes; Enzyme Inhibitors; Genistein; Isoflavones; Membrane Potentials; Microinjections; Patch-Clamp Techniques; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptor Protein-Tyrosine Kinases; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Fibroblast Growth Factor; Stellate Ganglion; Synapses; Synaptic Transmission; Tyrosine; Vanadates | 1997 |
A role for tyrosine phosphorylation in generation of inositol phosphates and prostacyclin production in endothelial cells.
Topics: Arachidonic Acid; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Histamine; Humans; Inositol Phosphates; Isoenzymes; Phosphorylation; Protein Kinase Inhibitors; Thrombin; Type C Phospholipases; Tyrosine; Vanadates | 1997 |
Muscarinic receptor-stimulated cytosol-membrane translocation of RhoA.
Topics: Atropine; Biological Transport; Carbachol; Catechols; Cell Line; Cell Membrane; Cell Membrane Permeability; Cytosol; Digitonin; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Isoflavones; Kidney; Muscarinic Agonists; Muscarinic Antagonists; Nitriles; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptor, Muscarinic M3; Receptors, Muscarinic; rhoA GTP-Binding Protein; Tyrphostins; Vanadates | 1997 |
Regulation of signal transducer and activator of transcription (STAT) 5b activation by the temporal pattern of growth hormone stimulation.
Topics: Animals; Cell Line; DNA-Binding Proteins; Enzyme Inhibitors; Female; Growth Hormone; Human Growth Hormone; Janus Kinase 2; Liver; Male; Milk Proteins; Periodicity; Phosphorylation; Prolactin; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Pulsatile Flow; Rats; Recombinant Proteins; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Transcription, Genetic; Vanadates | 1997 |
Cyclic changes in the organization of cell adhesions and the associated cytoskeleton, induced by stimulation of tyrosine phosphorylation in bovine aortic endothelial cells.
Topics: Animals; Aorta; Cattle; Cell Adhesion; Cells, Cultured; Endothelium, Vascular; Epidermal Growth Factor; Fluorescent Antibody Technique, Indirect; Intercellular Junctions; Microscopy, Fluorescence; Phosphorylation; Tyrosine; Vanadates | 1997 |
The receptor-like protein-tyrosine phosphatase DEP-1 is constitutively associated with a 64-kDa protein serine/threonine kinase.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Breast Neoplasms; Cell Line; Cloning, Molecular; Conserved Sequence; Female; Humans; Kinetics; Molecular Weight; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Vanadates | 1997 |
Interaction of the adaptor protein Shc and the adhesion molecule cadherin.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Sequence; Animals; Cadherins; Cell Adhesion; Cell Size; Enzyme Inhibitors; Epidermal Growth Factor; Genetic Techniques; Mice; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatases; Proteins; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; src Homology Domains; Tyrosine; Vanadates | 1997 |
Modulation of protein tyrosine phosphorylation by the extracellular matrix.
Topics: 3T3 Cells; Animals; Drug Combinations; Extracellular Matrix; Fibrin; Fibronectins; Mice; Phosphorylation; Rats; Tyrosine; Vanadates | 1997 |
Proliferative and morphological changes induced by vanadium compounds on Swiss 3T3 fibroblasts.
Topics: 3T3 Cells; Animals; Cell Division; Cells, Cultured; Enzyme Inhibitors; Mice; Oxidation-Reduction; Structure-Activity Relationship; Vanadates | 1997 |
Requirement for tyrosine phosphatase during serotonergic neuromodulation by protein kinase C.
Topics: Action Potentials; Animals; Cells, Cultured; Enzyme Inhibitors; Leeches; Neurons; Protein Kinase C; Protein Tyrosine Phosphatases; Serotonin; Vanadates | 1997 |
Inhibition of protein tyrosine phosphatases causes phosphorylation of tyrosine-331 in the p60 TNF receptor and inactivates the receptor-associated kinase.
Topics: Amino Acid Sequence; Antigens, CD; Binding Sites; Cytoplasm; Enzyme Activation; Enzyme Inhibitors; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Okadaic Acid; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins pp60(c-src); Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Recombinant Fusion Proteins; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine; Vanadates | 1997 |
Pervanadate elicits proliferation and mediates activation of mitogen-activated protein (MAP) kinase in the nucleus.
Topics: Animals; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Nucleus; Cells, Cultured; Enzyme Activation; Fibroblasts; Mice; Mice, Inbred CBA; Vanadates | 1997 |
Differential T cell receptor-mediated signaling in naive and memory CD4 T cells.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; CD3 Complex; CD4-Positive T-Lymphocytes; Enzyme Precursors; Female; Immunologic Memory; In Vitro Techniques; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Peptide Fragments; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Signal Transduction; Syk Kinase; T-Lymphocyte Subsets; Tyrosine; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 1997 |
Pervanadate-induced adhesion of CD4+ T cell to fibronectin is associated with tyrosine phosphorylation of paxillin.
Topics: CD4-Positive T-Lymphocytes; Cell Adhesion; Cell Adhesion Molecules; Cells, Cultured; Cytochalasin B; Cytoskeletal Proteins; Cytoskeleton; Enzyme Inhibitors; Fibronectins; Humans; Lymphocyte Activation; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Time Factors; Vanadates | 1997 |
Lck phosphorylates the activation loop tyrosine of the Itk kinase domain and activates Itk kinase activity.
Topics: Amino Acid Sequence; Animals; Cell Line; Conserved Sequence; Enzyme Activation; Humans; Jurkat Cells; Kinetics; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Sequence Data; Mutagenesis, Site-Directed; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphotyrosine; Point Mutation; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Recombinant Proteins; Spodoptera; src-Family Kinases; T-Lymphocytes; Transfection; Tyrosine; Vanadates | 1997 |
Induction of endothelial cell surface adhesion molecules by tumor necrosis factor is blocked by protein tyrosine phosphatase inhibitors: role of the nuclear transcription factor NF-kappa B.
Topics: Arsenicals; Cell Adhesion; Cells; Cells, Cultured; Diamide; DNA-Binding Proteins; E-Selectin; Endothelium, Vascular; Enzyme Inhibitors; Humans; Intercellular Adhesion Molecule-1; Monocytes; NF-kappa B; Protein Tyrosine Phosphatases; Signal Transduction; Tumor Necrosis Factor-alpha; Vanadates; Vascular Cell Adhesion Molecule-1 | 1997 |
Phosphorylation of erythropoietin receptors in the endoplasmic reticulum by pervanadate-mediated inhibition of tyrosine phosphatases.
Topics: Animals; Cell Line; COS Cells; Endoplasmic Reticulum; Enzyme Inhibitors; Fetus; Hexosaminidases; Janus Kinase 2; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Mice; Mice, Inbred C57BL; Peptide Fragments; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Erythropoietin; Recombinant Proteins; Transfection; Vanadates | 1997 |
Expression of voltage-gated potassium channels decreases cellular protein tyrosine phosphorylation.
Topics: Cells, Cultured; ErbB Receptors; Humans; Ion Channel Gating; Ion Transport; Kv1.3 Potassium Channel; Oncogene Protein pp60(v-src); Phosphorylation; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Signal Transduction; Transfection; Valinomycin; Vanadates | 1997 |
Modulation of rod photoreceptor cyclic nucleotide-gated channels by tyrosine phosphorylation.
Topics: Adenosine Triphosphate; Animals; Cyclic GMP; Enzyme Inhibitors; Eye Proteins; Hydroquinones; Ion Channel Gating; Marine Toxins; Microcystins; Okadaic Acid; Oocytes; Oxazoles; Patch-Clamp Techniques; Peptides, Cyclic; Phenols; Phosphorylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Rod Cell Outer Segment; Staurosporine; Vanadates; Xenopus laevis | 1997 |
Pervanadate inhibits volume-sensitive chloride current in bovine chromaffin cells.
Topics: Animals; Benzylidene Compounds; Cattle; Cells, Cultured; Chloride Channels; Chromaffin System; Electric Conductivity; Enzyme Inhibitors; Genistein; Guanosine 5'-O-(3-Thiotriphosphate); Nitriles; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tyrphostins; Vanadates | 1998 |
The phosphatidylinositol polyphosphate 5-phosphatase SHIP and the protein tyrosine phosphatase SHP-2 form a complex in hematopoietic cells which can be regulated by BCR/ABL and growth factors.
Topics: Animals; Cell Line; Cell Line, Transformed; Erythropoietin; Fusion Proteins, bcr-abl; Hematopoietic Stem Cells; Interleukin-3; Intracellular Signaling Peptides and Proteins; Mice; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Vanadates | 1997 |
Inhibition of antagonist binding to human brain muscarinic receptor by vanadium compounds.
Topics: Glutathione; Humans; In Vitro Techniques; Motor Cortex; Muscarinic Antagonists; Quinuclidinyl Benzilate; Receptors, Muscarinic; Vanadates | 1997 |
Effects of protein tyrosine phosphatase inhibitors on EGF- and insulin-dependent mammary epithelial cell growth.
Topics: Animals; Cell Division; Cells, Cultured; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Female; Insulin; Mammary Glands, Animal; Mice; Mice, Inbred BALB C; Phosphotyrosine; Protein Tyrosine Phosphatases; Tetradecanoylphorbol Acetate; Vanadates | 1998 |
Differential regulation by calcium reveals distinct signaling requirements for the activation of Akt and p70S6k.
Topics: 3T3 Cells; Androstadienes; Animals; Calcium; Down-Regulation; Epidermal Growth Factor; Ionomycin; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Ribosomal Protein S6 Kinases; Signal Transduction; Tetradecanoylphorbol Acetate; Vanadates; Wortmannin | 1998 |
Altered cell adhesion activity by pervanadate due to the dissociation of alpha-catenin from the E-cadherin.catenin complex.
Topics: alpha Catenin; Cadherins; Cell Adhesion; Cytoskeletal Proteins; Humans; Precipitin Tests; Protein Binding; Recombinant Fusion Proteins; Tumor Cells, Cultured; Vanadates | 1998 |
Phospholipase D activity in L1210 cells: a model for oleate-activated phospholipase D in intact mammalian cells.
Topics: ADP-Ribosylation Factors; Animals; Cell Differentiation; Dose-Response Relationship, Drug; Enzyme Activation; Fatty Acids, Unsaturated; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); HL-60 Cells; Humans; Leukemia L1210; Melitten; Mice; Oleic Acid; Phospholipase D; Tetradecanoylphorbol Acetate; Vanadates | 1998 |
Regulation of mammary differentiation by extracellular matrix involves protein-tyrosine phosphatases.
Topics: Animals; Basement Membrane; Cell Differentiation; Cells, Cultured; Collagen; DNA-Binding Proteins; Extracellular Matrix; Female; Integrin beta1; Janus Kinase 2; Mammary Glands, Animal; Mice; Mice, Inbred ICR; Milk Proteins; Phosphotyrosine; Pregnancy; Prolactin; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Prolactin; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Vanadates | 1998 |
Properties of pervanadate and permolybdate. Connexin43, phosphatase inhibition, and thiol reactivity as model systems.
Topics: Animals; Catalase; Cells, Cultured; Connexin 43; Cricetinae; Dose-Response Relationship, Drug; Drug Stability; Embryo, Mammalian; Enzyme Inhibitors; Ethylmaleimide; Gap Junctions; Kinetics; Mesocricetus; Models, Chemical; Molybdenum; Oxides; Phosphorylation; Protein Tyrosine Phosphatases; Structure-Activity Relationship; Sulfhydryl Compounds; Vanadates | 1998 |
The amino-terminal Src homology 2 domain of phospholipase C gamma 1 is essential for TCR-induced tyrosine phosphorylation of phospholipase C gamma 1.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Arginine; Cattle; ErbB Receptors; Glutathione Transferase; GRB2 Adaptor Protein; Humans; Isoenzymes; Jurkat Cells; Mutagenesis, Site-Directed; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Proteins; Receptor-CD3 Complex, Antigen, T-Cell; Recombinant Fusion Proteins; src Homology Domains; Type C Phospholipases; Tyrosine; Vanadates | 1998 |
Pervanadate inhibits mitogen-activated protein kinase kinase-1 in a p38MAPK-dependent manner.
Topics: Activating Transcription Factor 2; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Cyclic AMP Response Element-Binding Protein; Enzyme Activation; Enzyme Inhibitors; Imidazoles; MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; p38 Mitogen-Activated Protein Kinases; Papio; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; Recombinant Fusion Proteins; Transcription Factors; Vanadates | 1998 |
Hypotonic-stimulated taurine efflux in skate erythrocytes: regulation by tyrosine phosphatase activity.
Topics: Adenosine Triphosphate; Animals; Anion Exchange Protein 1, Erythrocyte; Enzyme Inhibitors; Erythrocytes; Hypotonic Solutions; Phosphotyrosine; Protein Tyrosine Phosphatases; Skates, Fish; Taurine; Vanadates | 1998 |
Pervanadate stimulates amylase release and protein tyrosine phosphorylation of paxillin and p125(FAK) in differentiated AR4-2J pancreatic acinar cells.
Topics: Amylases; Animals; Cell Adhesion Molecules; Cell Line; Cells, Cultured; Cytoskeletal Proteins; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Genistein; Molecular Weight; Nitriles; Pancreas; Paxillin; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptor, Insulin; Tyrphostins; Vanadates | 1998 |
Cadherin mediated cell-cell adhesion is regulated by tyrosine phosphatases in human keratinocytes.
Topics: Actins; Cadherins; Calcium; Cell Adhesion; Cytoskeleton; Humans; Intercellular Junctions; Keratinocytes; Macromolecular Substances; Phosphorylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Vanadates | 1998 |
A role of tyrosine phosphatase in acetylcholine receptor cluster dispersal and formation.
Topics: Animals; Cells, Cultured; Coculture Techniques; Diffusion; Enzyme Inhibitors; Muscles; Neurons; Protein Tyrosine Phosphatases; Receptor Aggregation; Receptors, Cholinergic; Signal Transduction; Vanadates; Xenopus | 1998 |
Stimulation of primed neutrophils by soluble immune complexes: priming leads to enhanced intracellular Ca2+ elevations, activation of phospholipase D, and activation of the NADPH oxidase.
Topics: Aniline Compounds; Antigen-Antibody Complex; Calcium; Enzyme Activation; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Hydroquinones; NADPH Oxidases; Neutrophils; Phospholipase D; Phosphorylation; Phosphotyrosine; Platelet Activating Factor; Protein-Tyrosine Kinases; Reactive Oxygen Species; Respiratory Burst; Signal Transduction; Vanadates; Xanthenes | 1998 |
Aberrant integrin (CR4; alpha(x)beta2; CD11c/CD18) oscillations on neutrophils in a mild form of pyoderma gangrenosum.
Topics: Adult; Animals; CD18 Antigens; Cell Polarity; Female; Humans; Integrin alphaXbeta2; Mice; Neutrophils; Pyoderma Gangrenosum; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Vanadates | 1998 |
Tyrosine phosphorylation and proteolysis. Pervanadate-induced, metalloprotease-dependent cleavage of the ErbB-4 receptor and amphiregulin.
Topics: Amphiregulin; Animals; Arsenicals; EGF Family of Proteins; Enzyme Inhibitors; ErbB Receptors; Glycoproteins; Growth Substances; Intercellular Signaling Peptides and Proteins; Metalloendopeptidases; Mutation; Peptide Fragments; Phenylalanine; Phosphorylation; Protein Kinase C; Protein Tyrosine Phosphatases; Pyrrolidines; Receptor Protein-Tyrosine Kinases; Receptor, ErbB-4; Receptors, Cell Surface; Thiocarbamates; Thiophenes; Tumor Cells, Cultured; Tyrosine; Vanadates | 1998 |
5-HT potentiation of the GABA(A) response in the rat sacral dorsal commissural neurones.
Topics: Animals; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; In Vitro Techniques; Isoquinolines; Membrane Potentials; Neurons; Okadaic Acid; Patch-Clamp Techniques; Protein Kinase C; Rats; Rats, Wistar; Receptors, GABA-A; Serotonin; Signal Transduction; Spinal Cord; Sulfonamides; Vanadates | 1998 |
Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta.
Topics: Animals; Biological Transport; Gene Expression Regulation, Enzymologic; Isoenzymes; Mast Cells; Membrane Proteins; Phosphorylation; Protein Binding; Protein Kinase C; Protein Kinase C-delta; Proto-Oncogene Proteins pp60(c-src); Rats; Receptors, IgE; Recombinant Proteins; src-Family Kinases; Tumor Cells, Cultured; Tyrosine; Vanadates | 1998 |
Modulation of olfactory bulb neuron potassium current by tyrosine phosphorylation.
Topics: Animals; Cell Line; Cells, Cultured; CSK Tyrosine-Protein Kinase; DNA Mutational Analysis; Electric Conductivity; Humans; Insulin; Neurons; Olfactory Bulb; Phosphorylation; Potassium; Potassium Channels; Potassium Channels, Voltage-Gated; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Shaw Potassium Channels; src-Family Kinases; Tyrosine; Vanadates | 1998 |
Characterisation of alpha-dystrobrevin in muscle.
Topics: Agrin; Amino Acid Sequence; Animals; Base Sequence; Brain; Cell Line; Cytoskeletal Proteins; Disease Models, Animal; Dystrophin-Associated Proteins; Fetus; Humans; Membrane Proteins; Mice; Mice, Inbred mdx; Molecular Sequence Data; Muscle Proteins; Muscle, Skeletal; Neuropeptides; Phosphotyrosine; Protein Isoforms; Synapses; Utrophin; Vanadates | 1998 |
SLP-65: a new signaling component in B lymphocytes which requires expression of the antigen receptor for phosphorylation.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; B-Lymphocytes; Base Sequence; Carrier Proteins; Cell Cycle Proteins; DNA, Complementary; Enzyme Inhibitors; GRB2 Adaptor Protein; Humans; Hydrogen Peroxide; Immunoglobulin delta-Chains; Immunoglobulin mu-Chains; Molecular Sequence Data; Phosphoproteins; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Rabbits; Receptors, Antigen, B-Cell; Signal Transduction; Tumor Cells, Cultured; Vanadates | 1998 |
Tyrosine-phosphorylation-dependent and rho-protein-mediated control of cellular phosphatidylinositol 4,5-bisphosphate levels.
Topics: ADP-Ribosylation Factors; Bacterial Proteins; Bacterial Toxins; Cell Line; Clostridioides difficile; Enzyme Activation; Genistein; GTP Phosphohydrolases; GTP-Binding Proteins; Humans; Membrane Proteins; Phosphatidylinositol 4,5-Diphosphate; Phospholipase D; Phosphorylation; rhoB GTP-Binding Protein; Tyrosine; Tyrphostins; Vanadates | 1998 |
Pervanadate-triggered MAP kinase activation and cell proliferation are not sensitive to PD 98059. Evidence for stimulus-dependent differential PD 98059 inhibition mechanism.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cells, Cultured; Enzyme Activation; Flavonoids; Immunohistochemistry; Mice; Mice, Inbred C3H; Signal Transduction; Vanadates | 1998 |
Transduction pathways involved in rapid hormone receptor regulation in the mammary epithelium.
Topics: Androstadienes; Animals; Calcimycin; Cell Membrane; Cyclic GMP; Down-Regulation; Epidermal Growth Factor; Epithelial Cells; ErbB Receptors; Female; Gene Products, env; Genistein; Mammary Glands, Animal; Mammary Tumor Virus, Mouse; Mice; Mice, Inbred C3H; Models, Biological; Nitric Oxide; Nitroprusside; omega-N-Methylarginine; Organ Culture Techniques; Phosphatidylinositol 3-Kinases; Protein-Tyrosine Kinases; Receptors, Prolactin; Signal Transduction; Up-Regulation; Vanadates; Wortmannin | 1998 |
Modulation of normal human eosinophil chemotaxis in vitro by herbimycin A, erbstatin and pervanadate.
Topics: Benzoquinones; Chemokine CCL11; Chemokines, CC; Chemotactic Factors, Eosinophil; Chemotaxis, Leukocyte; Cytokines; Enzyme Inhibitors; Eosinophils; Humans; Hydroquinones; In Vitro Techniques; Lactams, Macrocyclic; Platelet Activating Factor; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Quinones; Rifabutin; Vanadates; Vasoactive Intestinal Peptide | 1998 |
Signal transduction in activation of human eosinophils: G protein-dependent and -independent pathways.
Topics: Asthma; Cell Degranulation; Enzyme Inhibitors; Eosinophils; Genistein; GTP-Binding Proteins; Humans; Immunoglobulin A, Secretory; In Vitro Techniques; Inositol Phosphates; Isoenzymes; Pertussis Toxin; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; Type C Phospholipases; Tyrosine; Vanadates; Virulence Factors, Bordetella | 1998 |
Tyrosine phosphatase inhibitors, vanadate and pervanadate, stimulate glucose transport and GLUT translocation in muscle cells by a mechanism independent of phosphatidylinositol 3-kinase and protein kinase C.
Topics: Androstadienes; Animals; Biological Transport; Cell Line; Cytochalasin D; Enzyme Inhibitors; Genes, myc; Glucose; Glucose Transporter Type 4; Insulin; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Nucleic Acid Synthesis Inhibitors; Phosphatidylinositol 3-Kinases; Protein Kinase C; Protein Tyrosine Phosphatases; Rats; Transfection; Vanadates; Wortmannin | 1998 |
Evidence for a tyrosine kinase-dependent activation of the adenylyl Cyclase/PKA cascade downstream from the G-protein-linked endothelin ETA receptor in vascular smooth muscle.
Topics: Adenylyl Cyclases; Animals; Benzoquinones; Colforsin; Coronary Vessels; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Genistein; GTP-Binding Proteins; In Vitro Techniques; Kinetics; Lactams, Macrocyclic; Muscle, Smooth, Vascular; Peptides; Protein-Tyrosine Kinases; Quinones; Receptor, Endothelin A; Receptors, Endothelin; Rifabutin; Signal Transduction; Swine; Vanadates; Viper Venoms | 1998 |
Developmental regulation of tyrosine phosphorylation of the NR2D NMDA glutamate receptor subunit in rat central nervous system.
Topics: Aging; Animals; Animals, Newborn; Brain; Enzyme Inhibitors; Phosphorylation; Precipitin Tests; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Thalamus; Tyrosine; Vanadates | 1998 |
ZAP-70 association with T cell receptor zeta (TCRzeta): fluorescence imaging of dynamic changes upon cellular stimulation.
Topics: Actins; Cell Membrane; Cytoskeleton; Cytosol; Gene Expression; Green Fluorescent Proteins; HeLa Cells; Humans; Image Processing, Computer-Assisted; Indicators and Reagents; Luminescent Proteins; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Membrane Proteins; Microtubules; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Recombinant Fusion Proteins; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 1998 |
Tyrosine unphosphorylated platelet SHP-1 is a substrate for calpain.
Topics: Blood Platelets; Calcimycin; Calcium Chloride; Calpain; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Platelet Activation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Substrate Specificity; Thrombin; Tyrosine; Vanadates | 1998 |
Tissue-specific expression of beta-catenin in normal mesenchyme and uveal melanomas and its effect on invasiveness.
Topics: 3T3 Cells; Adenomatous Polyposis Coli; Adult; Animals; beta Catenin; Cadherins; Calcium-Calmodulin-Dependent Protein Kinases; Cell Differentiation; Cell Line; Cell Membrane; Cytoplasm; Cytoskeletal Proteins; Dogs; Epithelium; Glycogen Synthase Kinase 3; Humans; Melanoma; Mesoderm; Mice; Neoplasm Invasiveness; Phenotype; Phosphorylation; Protein Tyrosine Phosphatases; Staining and Labeling; Trans-Activators; Tumor Cells, Cultured; Tyrosine; Uveal Neoplasms; Vanadates | 1998 |
Bruton's tyrosine kinase activity and inositol 1,4,5-trisphosphate production are not altered in DT40 lymphoma B cells exposed to power line frequency magnetic fields.
Topics: Agammaglobulinaemia Tyrosine Kinase; Antibodies; Electromagnetic Fields; Enzyme Activation; Enzyme Induction; Humans; Immunoglobulin M; Inositol 1,4,5-Trisphosphate; Lymphoma, B-Cell; Phosphorylation; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Vanadates | 1998 |
Inactivation and dephosphorylation of protein kinase Balpha (PKBalpha) promoted by hyperosmotic stress.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; 3T3 Cells; Animals; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; COS Cells; Down-Regulation; Humans; Isoenzymes; Membranes; Mice; Mitogens; Osmolar Concentration; Osmotic Pressure; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoprotein Phosphatases; Phosphoserine; Phosphothreonine; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Vanadates | 1998 |
Induction of the antigen receptor expression on B lymphocytes results in rapid competence for signaling of SLP-65 and Syk.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; B-Lymphocytes; Base Sequence; Biological Transport; Carrier Proteins; Cell Line; Enzyme Precursors; Gene Expression Regulation; Integrases; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Recombination, Genetic; Signal Transduction; src-Family Kinases; Syk Kinase; Tamoxifen; Transfection; Tyrosine; Vanadates; Viral Proteins | 1998 |
Pervanadate activates NADPH oxidase via protein kinase C-independent phosphorylation of p47-phox.
Topics: Amino Acid Sequence; Animals; Binding Sites; Biological Transport; Enzyme Activation; Guinea Pigs; Indoles; Maleimides; Mice; Molecular Sequence Data; NADPH Dehydrogenase; NADPH Oxidases; Neutrophils; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinases; Protein Tyrosine Phosphatases; Superoxides; Tetradecanoylphorbol Acetate; Vanadates | 1999 |
Termination of growth hormone pulse-induced STAT5b signaling.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cell Line; Cycloheximide; Cysteine Endopeptidases; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Growth Hormone; Janus Kinase 2; Leupeptins; Liver; Milk Proteins; Multienzyme Complexes; Phosphorylation; Proteasome Endopeptidase Complex; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Receptors, Somatotropin; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Vanadates | 1999 |
Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-kappaB activation.
Topics: Androstadienes; DNA-Binding Proteins; Enzyme Inhibitors; Humans; I-kappa B Proteins; Jurkat Cells; NF-kappa B; Peptides; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; src Homology Domains; Transcriptional Activation; Tumor Necrosis Factor-alpha; Vanadates; Wortmannin | 1999 |
Enteropathogenic Escherichia coli inhibits phagocytosis.
Topics: Animals; Cell Line; Enzyme Inhibitors; Escherichia coli; Kinetics; Macrophages; Mice; Phagocytosis; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Vanadates | 1999 |
Tyrosine kinases play a permissive role in glucose-induced insulin secretion from adult rat islets.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Calcium; Calcium Channels; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Inhibitors; Genistein; Glucose; Insulin; Insulin Secretion; Ion Transport; Islets of Langerhans; Isoflavones; Leupeptins; Phenylmethylsulfonyl Fluoride; Phosphorylation; Protein Kinase C; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Second Messenger Systems; Tetradecanoylphorbol Acetate; Tyrphostins; Vanadates | 1999 |
Down-regulation of liver JAK2-STAT5b signaling by the female plasma pattern of continuous growth hormone stimulation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Cycloheximide; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; Down-Regulation; Electrophoresis; Female; Genistein; Growth Hormone; Growth Inhibitors; Janus Kinase 2; Leupeptins; Liver; Male; Milk Proteins; Protein Synthesis Inhibitors; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Signal Transduction; STAT5 Transcription Factor; Staurosporine; Trans-Activators; Vanadates | 1999 |
Anopheles gambiae Ag-STAT, a new insect member of the STAT family, is activated in response to bacterial infection.
Topics: Amino Acid Sequence; Animals; Anopheles; Bacteria; Cell Nucleus; Cloning, Molecular; DNA-Binding Proteins; Evolution, Molecular; Fat Body; Gene Expression Regulation; Hemocytes; Insect Proteins; Molecular Sequence Data; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; src Homology Domains; Transcription Factors; Vanadates | 1999 |
The Csk homologous kinase, Chk, binds tyrosine phosphorylated paxillin in human blastic T cells.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Fractionation; Cell Membrane; Cells, Cultured; CSK Tyrosine-Protein Kinase; Cytoskeletal Proteins; Cytosol; Fibroblasts; Humans; Mice; Molecular Weight; Mutation; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Recombinant Fusion Proteins; src Homology Domains; src-Family Kinases; T-Lymphocytes; Vanadates | 1999 |
Interactions between two cytoskeleton-associated tyrosine kinases: calcium-dependent tyrosine kinase and focal adhesion tyrosine kinase.
Topics: Animals; Binding Sites; Calcium; Cell Adhesion Molecules; Cell Line; Cytoskeleton; Enzyme Activation; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Regulation, Enzymologic; Humans; Mutagenesis, Site-Directed; Mutation; Phosphorylation; Protein-Tyrosine Kinases; Rats; src Homology Domains; src-Family Kinases; Vanadates | 1999 |
Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells.
Topics: Breast Neoplasms; Endopeptidases; Humans; Hydroxamic Acids; Metalloendopeptidases; Phenylalanine; Phosphorylation; Protease Inhibitors; Receptor, ErbB-2; Thiophenes; Tissue Inhibitor of Metalloproteinase-1; Tumor Cells, Cultured; Tyrosine; Vanadates | 1999 |
The myeloid-specific sialic acid-binding receptor, CD33, associates with the protein-tyrosine phosphatases, SHP-1 and SHP-2.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Base Sequence; COS Cells; DNA Primers; Erythrocytes; Intracellular Signaling Peptides and Proteins; Mutagenesis, Site-Directed; N-Acetylneuraminic Acid; Phosphopeptides; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Sialic Acid Binding Ig-like Lectin 3; Tyrosine; Vanadates | 1999 |
The p38 mitogen-activated protein kinase cascade is not required for the stimulation of insulin secretion from rat islets of Langerhans.
Topics: Animals; Arsenites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Cells, Cultured; Colforsin; Enzyme Inhibitors; Glucose; Homeostasis; Imidazoles; Insulin; Insulin Secretion; Islets of Langerhans; Kinetics; Male; Mitogen-Activated Protein Kinases; Okadaic Acid; p38 Mitogen-Activated Protein Kinases; Phosphoprotein Phosphatases; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Sodium Compounds; Sorbitol; Tetradecanoylphorbol Acetate; Vanadates | 1999 |
Tyrosine phosphorylation/dephosphorylation controls capping of Fcgamma receptor II in U937 cells.
Topics: Arsenicals; Bacterial Proteins; Benzoquinones; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Genistein; Humans; Immunoblotting; Lactams, Macrocyclic; Microscopy, Fluorescence; Okadaic Acid; Phosphorylation; Quinones; Receptor Aggregation; Receptors, IgG; Rifabutin; Streptolysins; Temperature; Time Factors; Tyrosine; U937 Cells; Vanadates | 1999 |
Differential association of cytoplasmic signalling molecules SHP-1, SHP-2, SHIP and phospholipase C-gamma1 with PECAM-1/CD31.
Topics: Amino Acid Sequence; Binding Sites; Humans; Intracellular Signaling Peptides and Proteins; Isoenzymes; Molecular Sequence Data; Monocytes; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phospholipase C gamma; Phosphopeptides; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Platelet Endothelial Cell Adhesion Molecule-1; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Sequence Homology, Amino Acid; SH2 Domain-Containing Protein Tyrosine Phosphatases; Signal Transduction; src Homology Domains; Surface Plasmon Resonance; Type C Phospholipases; Vanadates | 1999 |
Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Androstadienes; Animals; Blood Proteins; Cell Line; Cell Nucleus; Enzyme Activation; Glucocorticoids; Humans; Immediate-Early Proteins; Insulin; Insulin-Like Growth Factor I; Molecular Sequence Data; Mutation; Nuclear Proteins; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoprotein Phosphatases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Signal Transduction; Sirolimus; Substrate Specificity; Vanadates; Wortmannin | 1999 |
Pervanadate-mediated tyrosine phosphorylation of keratins 8 and 19 via a p38 mitogen-activated protein kinase-dependent pathway.
Topics: Animals; Binding Sites; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Colon; Enzyme Inhibitors; Epidermal Growth Factor; Humans; Keratins; Mice; Mice, Transgenic; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Serine; Signal Transduction; Solubility; Tyrosine; Vanadates | 1999 |
Tyrosine phosphorylation of the proto-oncoprotein Raf-1 is regulated by Raf-1 itself and the phosphatase Cdc25A.
Topics: 3T3 Cells; Animals; cdc25 Phosphatases; Cell Line; Enzyme Activation; Enzyme Inhibitors; Janus Kinase 2; Mice; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rabbits; Spodoptera; Tyrosine; Vanadates | 1999 |
Inefficient phospholipase C activation and reduced Lck expression characterize the signaling defect of umbilical cord T lymphocytes.
Topics: Adult; CD3 Complex; Cell Division; Cells, Cultured; Enzyme Activation; Fetal Blood; Flow Cytometry; Humans; Ionomycin; Isoenzymes; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphatidylinositols; Protein-Tyrosine Kinases; Signal Transduction; T-Lymphocyte Subsets; Tetradecanoylphorbol Acetate; Type C Phospholipases; Vanadates | 1999 |
Human 70-kDa SHP-1L differs from 68-kDa SHP-1 in its C-terminal structure and catalytic activity.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Catalysis; Cloning, Molecular; COS Cells; Humans; Hydrogen-Ion Concentration; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Molecular Sequence Data; Molecular Weight; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 1999 |
Inhibition of tyrosine phosphatases induces apoptosis independent from the CD95 system.
Topics: Apoptosis; Caspase 3; Caspase 8; Caspase 9; Caspases; Cytochrome c Group; Enzyme Activation; Enzyme Inhibitors; fas Receptor; Humans; Intracellular Membranes; Jurkat Cells; Mitochondria; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; T-Lymphocytes; Tumor Cells, Cultured; Vanadates | 1999 |
Differential modulation of the tyrosine phosphorylation state of the insulin receptor by IRS (insulin receptor subunit) proteins.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Motifs; Animals; Insulin; Insulin Receptor Substrate Proteins; Mice; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Proteins; Receptor, Insulin; Recombinant Proteins; Sequence Deletion; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Stem Cells; Tyrosine; Vanadates | 1999 |
Corticotropin increases protein tyrosine phosphatase activity by a cAMP-dependent mechanism in rat adrenal gland.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adrenocorticotropic Hormone; Animals; Arsenicals; Cyclic AMP; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Male; Molecular Weight; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Signal Transduction; Subcellular Fractions; Vanadates; Zona Fasciculata | 1999 |
Novel association of the src family kinases, hck and c-fgr, with CCR3 receptor stimulation: A possible mechanism for eotaxin-induced human eosinophil chemotaxis.
Topics: Benzoquinones; Chemokine CCL11; Chemokines, CC; Chemotaxis, Leukocyte; Cytokines; Drug Synergism; Enzyme Inhibitors; Eosinophils; Humans; Lactams, Macrocyclic; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Quinones; Receptors, CCR3; Receptors, Chemokine; Rifabutin; src-Family Kinases; Tyrosine; Vanadates | 1999 |
Insulin stimulates ecdysteroid production through a conserved signaling cascade in the mosquito Aedes aegypti.
Topics: Aedes; Animals; Cattle; Ecdysteroids; Enzyme Inhibitors; Female; In Vitro Techniques; Insulin; Mitogen-Activated Protein Kinases; Okadaic Acid; Ovary; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Steroids; Vanadates | 1999 |
Ethanol inhibits astroglial cell proliferation by disruption of phospholipase D-mediated signaling.
Topics: 1-Butanol; Animals; Astrocytes; Becaplermin; Butanols; Cell Division; Culture Media, Serum-Free; DNA; Endothelin-1; Ethanol; Fetal Alcohol Spectrum Disorders; Genistein; Growth Inhibitors; Indoles; Nerve Tissue Proteins; Phosphatidic Acids; Phospholipase D; Phosphorylation; Platelet-Derived Growth Factor; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-sis; Rats; Signal Transduction; tert-Butyl Alcohol; Vanadates | 1999 |
Tyrosine phosphorylation of caveolin-1 in the endothelium.
Topics: Animals; Aorta; Cattle; Caveolin 1; Caveolins; Cells, Cultured; Endothelium, Vascular; Enzyme Inhibitors; Humans; Intracellular Membranes; Membrane Proteins; Microscopy, Immunoelectron; Oxidative Stress; Phosphorylation; Rats; Tyrosine; Umbilical Veins; Vanadates | 1999 |
Involvement of the membrane distal catalytic domain in pervanadate-induced tyrosine phosphorylation of receptor protein-tyrosine phosphatase alpha.
Topics: Catalytic Domain; Cell Membrane; Enzyme Inhibitors; Humans; Mutagenesis, Site-Directed; Neuroectodermal Tumors, Primitive, Peripheral; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; Recombinant Proteins; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
Cofactor and substrate binding to vanadium chloroperoxidase determined by UV-VIS spectroscopy and evidence for high affinity for pervanadate.
Topics: Apoenzymes; Ascomycota; Binding Sites; Chloride Peroxidase; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Mutagenesis, Site-Directed; Recombinant Proteins; Spectrophotometry, Ultraviolet; Substrate Specificity; Vanadates; Vanadium | 2000 |
Membrane cofactor protein (MCP; CD46): isoform-specific tyrosine phosphorylation.
Topics: Amino Acid Sequence; Animals; Antibodies, Monoclonal; Antigens, CD; Cell Line; CHO Cells; Complement Inactivator Proteins; Cricetinae; Cytoplasm; Humans; Jurkat Cells; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Membrane Cofactor Protein; Membrane Glycoproteins; Molecular Sequence Data; Peptide Fragments; Phosphorylation; Protein Isoforms; Proto-Oncogene Proteins pp60(c-src); Substrate Specificity; Tyrosine; Vanadates | 2000 |
14-3-3tau associates with a translational control factor FKBP12-rapamycin-associated protein in T-cells after stimulation by pervanadate.
Topics: 14-3-3 Proteins; Amino Acid Substitution; Animals; Binding Sites; Carrier Proteins; COS Cells; Humans; Immunophilins; Jurkat Cells; Lymphocyte Activation; Mutation; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Precipitin Tests; Protein Binding; Protein Isoforms; Protein Tyrosine Phosphatases; Proteins; Recombinant Fusion Proteins; T-Lymphocytes; TOR Serine-Threonine Kinases; Tyrosine 3-Monooxygenase; Vanadates | 2000 |
Tyrosine phosphorylation modulates arteriolar tone but is not fundamental to myogenic response.
Topics: Animals; Arterioles; Enzyme Inhibitors; Genistein; In Vitro Techniques; Intracellular Membranes; Male; Muscle, Smooth, Vascular; Osmolar Concentration; Phosphoric Monoester Hydrolases; Phosphorylation; Pressure; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrphostins; Vanadates; Vasoconstriction; Vasomotor System | 2000 |
Tyrosine phosphorylation of myelin P(0) and its implication in signal transduction.
Topics: Amino Acid Sequence; Animals; Animals, Newborn; Brain; Cell Line; Cloning, Molecular; Consensus Sequence; Humans; Mice; Mice, Inbred BALB C; Mutagenesis, Site-Directed; Myelin P0 Protein; Neurilemmoma; Phenylalanine; Phosphorylation; Phosphotyrosine; Recombinant Proteins; Sequence Alignment; Signal Transduction; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
Restrictive endothelial barrier function during normal angiogenesis in vivo: partial dependence on tyrosine dephosphorylation of beta-catenin.
Topics: Allantois; Animals; Antigens, CD; beta Catenin; Cadherins; Capillary Permeability; Cell Differentiation; Chick Embryo; Chorion; Cytoskeletal Proteins; Dextrans; Endothelium, Vascular; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Neovascularization, Physiologic; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Trans-Activators; Vanadates | 2000 |
Systematic analysis of the role of CD19 cytoplasmic tyrosines in enhancement of activation in Daudi human B cells: clustering of phospholipase C and Vav and of Grb2 and Sos with different CD19 tyrosines.
Topics: Adaptor Proteins, Signal Transducing; Adjuvants, Immunologic; Antigens, CD19; B-Lymphocytes; Calcium Signaling; Cell Cycle Proteins; Cytoplasm; Exons; GRB2 Adaptor Protein; Humans; Isoenzymes; Lymphocyte Activation; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Molecular Weight; Mutagenesis, Site-Directed; Peptide Mapping; Phospholipase C gamma; Phosphopeptides; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-vav; Receptors, Antigen, B-Cell; Son of Sevenless Protein, Drosophila; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 2000 |
Disruption of microtubules in living cells by tyrphostin AG-1714.
Topics: Animals; Cell Line; Dimerization; Enzyme Inhibitors; Humans; Mice; Microtubules; Paclitaxel; Phosphorylation; Phosphotyrosine; Tyrphostins; Vanadates | 2000 |
Pervanadate-induced nuclear factor-kappaB activation requires tyrosine phosphorylation and degradation of IkappaBalpha. Comparison with tumor necrosis factor-alpha.
Topics: Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; DNA-Binding Proteins; HeLa Cells; Humans; I-kappa B Proteins; Leupeptins; Multienzyme Complexes; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Proteasome Endopeptidase Complex; Protein Tyrosine Phosphatases; Transcription, Genetic; Tumor Necrosis Factor-alpha; Tyrosine; U937 Cells; Vanadates | 2000 |
Tumor necrosis factor-alpha-converting enzyme is required for cleavage of erbB4/HER4.
Topics: 3T3 Cells; ADAM Proteins; ADAM17 Protein; Animals; Clone Cells; Cloning, Molecular; Colforsin; Disintegrins; Drosophila Proteins; ErbB Receptors; Kinetics; Marine Toxins; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Mice, Knockout; Okadaic Acid; Oxazoles; Protein Isoforms; Receptor, ErbB-4; Recombinant Proteins; Substrate Specificity; Tetradecanoylphorbol Acetate; Thapsigargin; Transfection; Tumor Necrosis Factor-alpha; Vanadates | 2000 |
Role of Src kinases in the ADAM-mediated release of L1 adhesion molecule from human tumor cells.
Topics: Animals; Antigens, Surface; Breast Neoplasms; Cell Size; CHO Cells; Cricetinae; Disintegrins; Enzyme Inhibitors; Female; Flavonoids; Humans; Leukocyte L1 Antigen Complex; Membrane Glycoproteins; Metalloendopeptidases; Mice; Neural Cell Adhesion Molecules; Neuroblastoma; Phosphorylation; Protease Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Recombinant Proteins; Signal Transduction; src-Family Kinases; Tetradecanoylphorbol Acetate; Transfection; Tumor Cells, Cultured; Vanadates | 2000 |
Processing by endoplasmic reticulum mannosidases partitions a secretion-impaired glycoprotein into distinct disposal pathways.
Topics: alpha 1-Antitrypsin; Animals; Arsenicals; Carbohydrate Sequence; Endoplasmic Reticulum; Genetic Variation; Glycoproteins; Humans; Liver Neoplasms, Experimental; Mannosidases; Mice; Molecular Sequence Data; Okadaic Acid; Oligosaccharides; Recombinant Proteins; Sodium Fluoride; Transfection; Tumor Cells, Cultured; Vanadates | 2000 |
Tumor-derived mutated E-cadherin influences beta-catenin localization and increases susceptibility to actin cytoskeletal changes induced by pervanadate.
Topics: Actin Cytoskeleton; Actins; alpha Catenin; Animals; beta Catenin; Cadherins; Catenins; Cell Adhesion Molecules; Cell Line; Cytoskeletal Proteins; Cytoskeleton; Delta Catenin; Desmoplakins; Enzyme Inhibitors; Humans; Mice; Mutation; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Stomach Neoplasms; Trans-Activators; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells.
Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Fusion Proteins, bcr-abl; Hematopoietic Stem Cells; Humans; Hydrogen Peroxide; Megakaryocytes; Mice; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Reactive Oxygen Species; Rotenone; Signal Transduction; Vanadates | 2000 |
The pro- or anti-apoptotic function of NF-kappaB is determined by the nature of the apoptotic stimulus.
Topics: Apoptosis; Caspase 3; Caspases; Enzyme Activation; HeLa Cells; Humans; Hydrogen Peroxide; I-kappa B Proteins; Interleukin-6; NF-kappa B; Transfection; Tumor Necrosis Factor-alpha; Vanadates | 2000 |
Syk-dependent phosphorylation of microtubules in activated B-lymphocytes.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Biopolymers; Cell Line; Centrosome; Chickens; Cytoskeleton; Enzyme Inhibitors; Enzyme Precursors; Gene Deletion; Intracellular Signaling Peptides and Proteins; Lymphocyte Activation; Microtubules; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Syk Kinase; Tubulin; Vanadates | 2000 |
Identification of Grb10 as a direct substrate for members of the Src tyrosine kinase family.
Topics: Animals; CHO Cells; Cricetinae; GRB10 Adaptor Protein; Insulin; Mutagenesis, Site-Directed; Phosphorylation; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; src-Family Kinases; Substrate Specificity; Tyrosine; Vanadates | 2000 |
The serine and threonine residues in the Ig-alpha cytoplasmic tail negatively regulate immunoreceptor tyrosine-based activation motif-mediated signal transduction.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Antigens, CD; Carrier Proteins; CD79 Antigens; Cytoplasm; Enzyme Inhibitors; Humans; Immunoglobulin Fragments; Immunoglobulin Variable Region; Molecular Sequence Data; Phosphoproteins; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatases; Receptors, Antigen, B-Cell; Recombinant Fusion Proteins; Serine; Signal Transduction; Threonine; Tumor Cells, Cultured; Tyrosine; Vanadates | 2000 |
Heregulin-dependent trafficking and cleavage of ErbB-4.
Topics: Detergents; Enzyme Inhibitors; Humans; Hydrolysis; Kinetics; Ligands; Neuregulin-1; Phosphorylation; Protein Transport; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Vanadates | 2000 |
Tyrosine phosphorylation and cellular redistribution of ezrin in MDCK cells treated with pervanadate.
Topics: Amino Acid Sequence; Animals; Antibodies; Cell Line; Cell Membrane; Cytoskeletal Proteins; Cytosol; Dogs; Kidney; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Tyrosine; Vanadates | 2000 |
Pervanadate induces the hyperphosphorylation but not the activation of human heat shock factor 1.
Topics: DNA-Binding Proteins; Enzyme Inhibitors; Heat Shock Transcription Factors; Heat-Shock Proteins; HeLa Cells; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Signal Transduction; Transcription Factors; Vanadates | 2000 |
Enhancement of nuclear factor-kappaB activation and protein tyrosine phosphorylation by a tyrosine phosphatase inhibitor, pervanadate, involves reactive oxygen species in silica-stimulated macrophages.
Topics: Animals; Blotting, Western; Cell Line; Cell Nucleus; Electrophoresis; Enzyme Inhibitors; Macrophages; Mice; NF-kappa B; Precipitin Tests; Protein Tyrosine Phosphatases; Reactive Oxygen Species; Silicon Dioxide; Stimulation, Chemical; Tyrosine; Vanadates | 2000 |
Growth cone steering by receptor tyrosine phosphatase delta defines a distinct class of guidance cue.
Topics: Animals; Cells, Cultured; Chick Embryo; Enzyme Inhibitors; Growth Cones; Laminin; Neurons; Prosencephalon; Protein Tyrosine Phosphatases; Recombinant Fusion Proteins; Vanadates | 2000 |
Shf, a Shb-like adapter protein, is involved in PDGF-alpha-receptor regulation of apoptosis.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Apoptosis; Cell Division; Cloning, Molecular; Female; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice; Molecular Sequence Data; Phosphoproteins; Phosphotyrosine; Platelet-Derived Growth Factor; Proto-Oncogene Proteins; Receptor, Platelet-Derived Growth Factor alpha; Recombinant Proteins; Sequence Alignment; Sequence Homology, Amino Acid; src Homology Domains; Vanadates | 2000 |
The Src kinase p56(lck) up-regulates VLA-4 integrin affinity. Implications for rapid spontaneous and chemokine-triggered T cell adhesion to VCAM-1 and fibronectin.
Topics: Blotting, Western; Cell Adhesion; Dose-Response Relationship, Drug; Endothelium; Enzyme Inhibitors; Fibronectins; Flow Cytometry; Humans; Integrin alpha4beta1; Integrins; Interleukin-2; Jurkat Cells; Kinetics; Ligands; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphocytes; Phosphotyrosine; Protein Binding; Receptors, Lymphocyte Homing; Signal Transduction; T-Lymphocytes; Up-Regulation; Vanadates; Vascular Cell Adhesion Molecule-1 | 2001 |
Cholecystokinin octapeptide CCK-8 and carbachol reduce [(32)P]orthophosphate labeling of phosphatidylcholine without modifying phospholipase D activity in rat pancreatic acini.
Topics: Animals; Butanols; Carbachol; Enzyme Activation; Ethanol; Glycerophospholipids; Hydrogen Peroxide; Kinetics; Pancreas; Phosphates; Phosphatidic Acids; Phosphatidylcholines; Phospholipase D; Rats; Rats, Wistar; Sincalide; Tetradecanoylphorbol Acetate; Vanadates | 2000 |
Cell density regulates tyrosine phosphorylation and localization of focal adhesion kinase.
Topics: 3T3 Cells; Animals; Cell Adhesion; Cell Count; Detergents; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; HeLa Cells; Humans; Intracellular Fluid; Mice; Octoxynol; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Solubility; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
The lipid peroxidation product 4-hydroxy-2,3-nonenal inhibits constitutive and inducible activity of nuclear factor kappa B in neurons.
Topics: Aldehydes; Alzheimer Disease; Animals; Apoptosis; Cell Survival; Cells, Cultured; Cerebral Cortex; Cycloheximide; Cysteine Proteinase Inhibitors; Enzyme Inhibitors; Lipid Peroxidation; Nerve Degeneration; Neurons; NF-kappa B; Okadaic Acid; Protein Synthesis Inhibitors; Rats; Stroke; Transcription Factor AP-1; Vanadates | 2000 |
Cloning and characterization of a novel ITIM containing lectin-like immunoreceptor LLIR and its two transmembrane region deletion variants.
Topics: 3T3 Cells; Alternative Splicing; Amino Acid Sequence; Animals; B-Lymphocytes; Base Sequence; Blotting, Northern; Carcinogens; Cell Differentiation; Cell Line; Cell Membrane; Chromosome Mapping; Chromosomes, Human, Pair 12; Cloning, Molecular; Dendritic Cells; DNA, Complementary; Enzyme Inhibitors; Gene Deletion; HL-60 Cells; Humans; Immunoblotting; Lectins; Lectins, C-Type; Membrane Glycoproteins; Mice; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Biosynthesis; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Tetradecanoylphorbol Acetate; Tissue Distribution; Tumor Cells, Cultured; Up-Regulation; Vanadates | 2001 |
Tyrosine phosphorylation-dependent activation of NF-kappa B. Requirement for p56 LCK and ZAP-70 protein tyrosine kinases.
Topics: DNA; DNA-Binding Proteins; Enzyme Activation; Humans; Hydrogen Peroxide; I-kappa B Proteins; Jurkat Cells; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pyrazoles; Pyrimidines; Signal Transduction; src Homology Domains; Stilbenes; T-Lymphocytes; Transcriptional Activation; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 2001 |
Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling.
Topics: Adaptor Proteins, Signal Transducing; Animals; CD3 Complex; COS Cells; Enzyme Activation; Gene Expression Regulation, Enzymologic; GRB2 Adaptor Protein; Humans; Immunoblotting; Jurkat Cells; Kinetics; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Membrane Microdomains; Nuclear Proteins; Oncogene Proteins; Phosphorylation; Plasmids; Precipitin Tests; Proline; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Receptors, Antigen, T-Cell; Signal Transduction; Time Factors; Transfection; Tyrosine; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 2001 |
Residues Y429 and Y463 of the human CD5 are targeted by protein tyrosine kinases.
Topics: Amino Acid Substitution; Antibodies, Monoclonal; CD3 Complex; CD5 Antigens; Enzyme Activation; Humans; Jurkat Cells; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mutation; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Recombinant Fusion Proteins; T-Lymphocytes; Transfection; Tyrosine; Vanadates | 2001 |
Coupling of L-type calcium channels to neurotransmitter release at mouse motor nerve terminals.
Topics: Animals; Buffers; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Chelating Agents; Egtazic Acid; Elapid Venoms; Enzyme Inhibitors; Evoked Potentials; Ionophores; Mice; Motor Endplate; Motor Neurons; Muscle, Skeletal; Neurotransmitter Agents; Nitrendipine; Okadaic Acid; omega-Agatoxin IVA; omega-Conotoxin GVIA; Presynaptic Terminals; Synaptic Transmission; Vanadates | 2001 |
Modulation of PKCdelta tyrosine phosphorylation and activity in salivary and PC-12 cells by Src kinases.
Topics: Animals; Calcium; Carbachol; Carcinogens; Cholinergic Agents; Diglycerides; Enzyme Activation; Enzyme Inhibitors; Epithelial Cells; Estrenes; Isoenzymes; Male; Neurons; Parotid Gland; PC12 Cells; Phosphodiesterase Inhibitors; Phosphorylation; Protein Kinase C; Protein Kinase C-delta; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Serine; src-Family Kinases; Substance P; Tetradecanoylphorbol Acetate; Threonine; Tyrosine; Vanadates | 2001 |
Src-class kinases act within the agrin/MuSK pathway to regulate acetylcholine receptor phosphorylation, cytoskeletal anchoring, and clustering.
Topics: Agrin; Animals; Cell Line; COS Cells; Cytoskeleton; Fibroblasts; Macromolecular Substances; Mice; Muscle, Skeletal; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Quail; Receptor Aggregation; Receptor Protein-Tyrosine Kinases; Receptors, Cholinergic; Recombinant Fusion Proteins; Signal Transduction; src Homology Domains; src-Family Kinases; Transfection; Vanadates | 2001 |
Identification of Src phosphorylation sites in the catenin p120ctn.
Topics: Animals; Binding Sites; Blotting, Western; Catenins; Cell Adhesion Molecules; Cell Line; COS Cells; Cytoplasm; Delta Catenin; DNA Mutational Analysis; Electrophoresis, Gel, Two-Dimensional; Epidermal Growth Factor; Gene Deletion; Genes, Dominant; Glutathione Transferase; Humans; Mutagenesis, Site-Directed; Mutation; Phenylalanine; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins pp60(c-src); Transfection; Tyrosine; Vanadates | 2001 |
Release from tonic inhibition of T cell activation through transient displacement of C-terminal Src kinase (Csk) from lipid rafts.
Topics: Antigens, Polyomavirus Transforming; Cells, Cultured; CSK Tyrosine-Protein Kinase; Humans; Jurkat Cells; Lymphocyte Activation; Membrane Microdomains; Models, Biological; Muromonab-CD3; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptors, Antigen, T-Cell; Recombinant Proteins; src Homology Domains; src-Family Kinases; T-Lymphocytes; Transfection; Vanadates | 2001 |
Ligand stimulation reduces platelet-derived growth factor beta-receptor susceptibility to tyrosine dephosphorylation.
Topics: Agglutinins; Animals; Catalytic Domain; Cell Membrane; Cells, Cultured; Dimerization; Endothelium, Vascular; Enzyme Inhibitors; Ligands; Phosphorylation; Precipitin Tests; Protein Binding; Protein Phosphatase 1; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Receptor, Platelet-Derived Growth Factor beta; Recombinant Proteins; Sepharose; Swine; Transfection; Tyrosine; Vanadates | 2001 |
Tyrosine phosphorylation translocates beta-catenin from cell-->cell interface to the cytoplasm, but does not significantly enhance the LEF-1-dependent transactivating function.
Topics: 3T3 Cells; Animals; beta Catenin; Biological Transport; Cell Communication; Cell Membrane; Colonic Neoplasms; Cyclin D1; Cytoplasm; Cytoskeletal Proteins; DNA-Binding Proteins; Enzyme Inhibitors; Gene Expression; Humans; Luciferases; Lymphoid Enhancer-Binding Factor 1; Mice; Phosphorylation; Protein Tyrosine Phosphatases; Trans-Activators; Transcription Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
RAFTK/Pyk2 involvement in platelet activation is mediated by phosphoinositide 3-kinase.
Topics: Adenosine Diphosphate; Chromones; Collagen; Enzyme Inhibitors; Fibrinogen; Focal Adhesion Kinase 2; Humans; Intracellular Signaling Peptides and Proteins; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphoric Monoester Hydrolases; Phosphorylation; Platelet Activation; Precipitin Tests; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Thrombin; Vanadates | 2001 |
LH/chorionic gonadotropin signaling pathway involves protein tyrosine phosphatase activity downstream of protein kinase A activation: evidence of an obligatory step in steroid production by Leydig cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Analysis of Variance; Animals; Cell Line; Cells, Cultured; Chorionic Gonadotropin; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Enzyme Inhibitors; Gonadotropins, Pituitary; Leydig Cells; Luteinizing Hormone; Male; Oxygenases; Protein Tyrosine Phosphatases; Rats; Rats, Wistar; Signal Transduction; Testosterone; Vanadates | 2001 |
Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Amino Acid Sequence; Biological Transport; Cell Membrane; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors; Humans; Molecular Sequence Data; Mutation; Phosphorylation; Protein Serine-Threonine Kinases; Sequence Homology, Amino Acid; src-Family Kinases; Tyrosine; Vanadates | 2001 |
Epstein-Barr virus latent membrane protein 2A (LMP2A) employs the SLP-65 signaling module.
Topics: Adaptor Proteins, Signal Transducing; Animals; B-Lymphocytes; Base Sequence; Carrier Proteins; Cell Line; DNA Primers; Enzyme Inhibitors; Enzyme Precursors; Epstein-Barr Virus Infections; Female; Herpesvirus 4, Human; Humans; Hydrogen Peroxide; Intracellular Signaling Peptides and Proteins; Isoenzymes; Male; Mice; Mice, Knockout; Mice, Transgenic; Nuclear Proteins; Phospholipase C gamma; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Signal Transduction; Syk Kinase; Type C Phospholipases; Tyrosine; Vanadates; Viral Matrix Proteins | 2001 |
Rottlerin-independent attenuation of pervanadate-induced tyrosine phosphorylation events by protein kinase C-delta in hemopoietic cells.
Topics: Acetophenones; Animals; B-Lymphocytes; Benzopyrans; Cells, Cultured; Enzyme Inhibitors; Hematopoietic Stem Cells; Isoenzymes; Mast Cells; Mice; Mice, Knockout; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein Kinase C-delta; Protein Tyrosine Phosphatases; Receptors, IgE; Tumor Cells, Cultured; Vanadates | 2001 |
Tyrosine phosphorylation following alterations in arteriolar intraluminal pressure and wall tension.
Topics: Angiotensin II; Animals; Antibody Specificity; Arterioles; Blood Pressure; Calcium; Calcium Channel Blockers; Colforsin; Endothelium, Vascular; In Vitro Techniques; Male; Muscle, Smooth, Vascular; Phosphorylation; Phosphotyrosine; Physical Stimulation; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrphostins; Vanadates; Vasoconstriction; Vasodilator Agents; Verapamil | 2001 |
Specific inhibition of interleukin-4-dependent Stat6 activation by an intracellularly delivered peptide.
Topics: Antennapedia Homeodomain Protein; Cell Membrane Permeability; DNA-Binding Proteins; Endocytosis; Enzyme Inhibitors; Homeodomain Proteins; Humans; Interleukin-4; Milk Proteins; Nuclear Proteins; Peptide Fragments; Phosphorylation; Receptors, Interleukin-4; Recombinant Fusion Proteins; STAT5 Transcription Factor; STAT6 Transcription Factor; Trans-Activators; Transcription Factors; Transcriptional Activation; Tumor Cells, Cultured; Vanadates | 2001 |
G6b, a novel immunoglobulin superfamily member encoded in the human major histocompatibility complex, interacts with SHP-1 and SHP-2.
Topics: Amino Acid Sequence; Animals; COS Cells; Genes, Immunoglobulin; Glycosylation; Intracellular Signaling Peptides and Proteins; Major Histocompatibility Complex; Molecular Sequence Data; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Immunologic; Reverse Transcriptase Polymerase Chain Reaction; Vanadates | 2001 |
Hydrogen peroxide-mediated inhibition of lipopolysaccharide-stimulated inhibitory kappa B kinase activity in rat aortic smooth muscle cells.
Topics: Animals; Aorta; Cells, Cultured; DNA; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hydrogen Peroxide; I-kappa B Kinase; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Luciferases; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; NF-kappa B; Oxidants; p38 Mitogen-Activated Protein Kinases; Protein Binding; Protein Serine-Threonine Kinases; Rats; Recombinant Fusion Proteins; Signal Transduction; Time Factors; Vanadates | 2001 |
Control of the nuclear-cytoplasmic partitioning of annexin II by a nuclear export signal and by p11 binding.
Topics: Active Transport, Cell Nucleus; Amino Acid Sequence; Animals; Annexin A2; Antifungal Agents; Astrocytoma; Calcium; Calcium-Binding Proteins; Cell Line; Cell Nucleus; Cytoplasm; Detergents; Enzyme Inhibitors; Fatty Acids, Unsaturated; Fibroblasts; Genistein; Green Fluorescent Proteins; HeLa Cells; Humans; Ligands; Luminescent Proteins; Microscopy, Fluorescence; Molecular Sequence Data; Octoxynol; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Rats; Recombinant Fusion Proteins; S100 Proteins; Sequence Homology, Amino Acid; Temperature; Time Factors; Vanadates | 2001 |
Carcinoembryonic antigen cell adhesion molecule 1 directly associates with cytoskeleton proteins actin and tropomyosin.
Topics: Actins; Amino Acids; Animals; Antigens, CD; Antigens, Differentiation; Biotinylation; Carcinoembryonic Antigen; Cell Adhesion; Cell Adhesion Molecules; Cytoplasm; Cytoskeleton; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epithelial Cells; Glutathione Transferase; Humans; Kinetics; Mass Spectrometry; Mice; Microscopy, Confocal; Peptides; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Recombinant Fusion Proteins; Recombinant Proteins; Surface Plasmon Resonance; Time Factors; Transfection; Tropomyosin; Tumor Cells, Cultured; Vanadates | 2001 |
Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Carrier Proteins; Cell Division; Cell Line; Cell Line, Transformed; Cell Membrane; Cell Size; Enzyme Activation; Genes, fos; Humans; Insulin; Insulin-Like Growth Factor I; Membrane Proteins; Mice; Mice, Nude; Molecular Sequence Data; Neoplasms, Experimental; Oncogene Protein v-akt; Palmitoyl-CoA Hydrolase; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Retroviridae Proteins, Oncogenic; Signal Transduction; Thiolester Hydrolases; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Vanadates | 2001 |
Direct effect of bispecific anti-CD33 x anti-CD64 antibody on proliferation and signaling in myeloid cells.
Topics: Antibodies, Bispecific; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cell Division; Humans; Interferon-gamma; Leukemia, Myeloid, Acute; Monocytes; Phagocytosis; Phosphorylation; Receptors, IgG; Sialic Acid Binding Ig-like Lectin 3; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
Modulation of nicotinic acetylcholine receptor turnover by tyrosine phosphorylation in rat myotubes.
Topics: Animals; Biotinylation; Bungarotoxins; Cells, Cultured; Cytoskeleton; Enzyme Inhibitors; Iodine Radioisotopes; Muscle Fibers, Skeletal; Neuromuscular Junction; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Nicotinic; Tyrosine; Vanadates | 2001 |
SH2 domain-containing inositol polyphosphate 5'-phosphatase is the main mediator of the inhibitory action of the mast cell function-associated antigen.
Topics: Amino Acid Sequence; Animals; beta-N-Acetylhexosaminidases; Enzyme Inhibitors; Immunosuppressive Agents; Lectins, C-Type; Mast Cells; Membrane Glycoproteins; Molecular Sequence Data; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Binding; Rats; Receptors, IgE; src Homology Domains; src-Family Kinases; Tumor Cells, Cultured; Tyrosine; Vanadates | 2001 |
Involvement of phospholipase D in oxidative stress-induced necrosis of vascular smooth muscle cells.
Topics: Animals; Aorta; Butanols; Calcium; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Hydrogen Peroxide; Muscle, Smooth, Vascular; Necrosis; Oxidative Stress; Phospholipase D; Rats; Time Factors; Vanadates | 2001 |
Tyrosine phosphatases SHP-1 and SHP-2 are associated with distinct tyrosine-phosphorylated proteins.
Topics: Animals; Cattle; Cell Line; Enzyme Inhibitors; Humans; Intracellular Signaling Peptides and Proteins; Mice; Mice, Inbred BALB C; Organ Specificity; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proteins; Rats; SH2 Domain-Containing Protein Tyrosine Phosphatases; Tyrosine; Vanadates | 2002 |
Role of tyrosine kinase activity in alpha-adrenergic inhibition of the beta-adrenergically regulated L-type Ca(2+) current in guinea-pig ventricular myocytes.
Topics: Adrenergic alpha-Agonists; Animals; Calcium Channels, L-Type; Electric Conductivity; Enzyme Inhibitors; Guinea Pigs; Histamine; Histamine Antagonists; Myocardium; Protein-Tyrosine Kinases; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Vanadates | 2001 |
Functional analysis of discoidin domain receptor 1: effect of adhesion on DDR1 phosphorylation.
Topics: 3T3 Cells; Animals; Cell Adhesion; Collagen; Discoidin Domain Receptors; Enzyme Inhibitors; Humans; K562 Cells; Mice; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Tyrosine Phosphatases; Rats; Receptor Protein-Tyrosine Kinases; Receptors, Mitogen; Signal Transduction; Tumor Cells, Cultured; Vanadates | 2002 |
alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells.
Topics: alpha-Synuclein; Animals; Blood Proteins; Blotting, Western; Brain; Cell Line; Cytoplasm; DNA, Complementary; Enzyme Activation; Enzyme Inhibitors; Eosinophils; Glutathione Transferase; Humans; Microscopy, Fluorescence; Mutation; Nerve Tissue Proteins; Phospholipase D; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Binding; Protein Isoforms; Protein Structure, Tertiary; Rats; Recombinant Fusion Proteins; Synucleins; Tetradecanoylphorbol Acetate; Time Factors; Transfection; Tyrosine; Vanadates | 2002 |
Differential involvement of Src family kinases in pervanadate-mediated responses in rat myometrial cells.
Topics: Animals; Cells, Cultured; DNA; Enzyme Inhibitors; Female; Inositol Phosphates; Isoenzymes; Kinetics; Mitogen-Activated Protein Kinases; Myometrium; Phospholipase C gamma; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins pp60(c-src); Rats; Rats, Wistar; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Type C Phospholipases; Vanadates | 2002 |
Living with lethal PIP3 levels: viability of flies lacking PTEN restored by a PH domain mutation in Akt/PKB.
Topics: Alleles; Amino Acid Substitution; Animals; Cell Line; Cell Membrane; Drosophila melanogaster; Drosophila Proteins; Eye; Female; Genes, Insect; Humans; Insulin; Male; Mutation; Phenotype; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphoric Monoester Hydrolases; Photoreceptor Cells, Invertebrate; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Transfection; Tumor Suppressor Proteins; Vanadates | 2002 |
Interdependence of steroidogenesis and shape changes in Y1 adrenocortical cells: studies with inhibitors of phosphoprotein phosphatases.
Topics: Adrenal Cortex; Animals; Cell Size; Colforsin; Cyclic AMP-Dependent Protein Kinases; Cytoskeletal Proteins; Dipeptides; Enzyme Activation; Enzyme Inhibitors; Marine Toxins; Mice; Oxazoles; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Pregnenolone; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Tumor Cells, Cultured; Vanadates | 2002 |
Tyrosine phosphorylation of the beta-amyloid precursor protein cytoplasmic tail promotes interaction with Shc.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Amino Acid Motifs; Amyloid beta-Protein Precursor; Animals; Apoptosis; Binding Sites; Brain; Cell Differentiation; Cell Line; Cell Membrane; COS Cells; Cytoplasm; Enzyme Inhibitors; Glutathione Transferase; Humans; Immunoblotting; Mice; Mice, Inbred BALB C; Models, Biological; Nerve Tissue Proteins; Neuroblastoma; Neuropeptides; Phosphorylation; Precipitin Tests; Protein Binding; Protein Biosynthesis; Protein Structure, Tertiary; Proteins; Receptor, trkA; Recombinant Fusion Proteins; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Src Homology 2 Domain-Containing, Transforming Protein 3; Transcription, Genetic; Tyrosine; Vanadates | 2002 |
Nuclear translocation of cell adhesion kinase beta/proline-rich tyrosine kinase 2.
Topics: Active Transport, Cell Nucleus; Amino Acid Substitution; Animals; Binding Sites; Cell Line; Cell Membrane; Cell Nucleus; Cellular Apoptosis Susceptibility Protein; Chlorocebus aethiops; COS Cells; Cytoplasm; Cytoskeletal Proteins; Dimethyl Sulfoxide; DNA-Binding Proteins; Dogs; Fatty Acids, Unsaturated; Focal Adhesion Kinase 2; Humans; Intracellular Signaling Peptides and Proteins; LIM Domain Proteins; Osmolar Concentration; Paxillin; Phosphoproteins; Point Mutation; Protein-Tyrosine Kinases; Rats; Subcellular Fractions; Vanadates | 2002 |
The p38 mitogen-activated protein kinase is involved in stress-induced phospholipase D activation in vascular smooth muscle cells.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Imidazoles; Mannitol; MAP Kinase Kinase 6; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Phospholipase D; Protein Kinase C; Pyridines; Rats; Rats, Sprague-Dawley; Tetradecanoylphorbol Acetate; Time Factors; Vanadates | 2002 |
Mechanisms underlying pervanadate-induced contraction of rat cremaster muscle arterioles.
Topics: Animals; Arterioles; Azepines; Calcium; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinases; Colforsin; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Male; Muscle, Skeletal; Myosin-Light-Chain Kinase; Naphthalenes; Nifedipine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Sulfonamides; Tyrphostins; Vanadates; Vasoconstriction | 2002 |
Cloning and characterization of a testis and brain-specific isoform of mouse 3'-phosphoinositide-dependent protein kinase-1, mPDK-1 beta.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Aging; Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Brain; CHO Cells; Cloning, Molecular; Cricetinae; Female; Humans; Insulin; Isoenzymes; Male; Mice; Molecular Sequence Data; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; Sequence Alignment; Spermatogenesis; src-Family Kinases; Testis; Tyrosine; Vanadates | 2002 |
BCR mutants deficient in ligand-independent and more sensitive for ligand-dependent signaling.
Topics: Antigens; Humans; Immunoglobulin D; Mutation; Phosphorylation; Receptors, Antigen, B-Cell; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 2002 |
Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase.
Topics: Animals; Carcinoma; COS Cells; Culture Media, Serum-Free; Enzyme Inhibitors; Female; Genes, Reporter; Humans; Insulin-Like Growth Factor I; Mutagenesis, Site-Directed; Ovarian Neoplasms; Peptide Mapping; Phosphatidylinositol 3-Kinases; Phosphopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Tumor Cells, Cultured; Tyrosine; Vanadates | 2002 |
Regulation of the EphA2 kinase by the low molecular weight tyrosine phosphatase induces transformation.
Topics: Breast Neoplasms; Cell Line, Transformed; Cells, Cultured; Chelating Agents; Dose-Response Relationship, Drug; Egtazic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Epithelial Cells; Gene Expression Regulation, Enzymologic; Humans; Immunoblotting; Isoenzymes; Oligonucleotides, Antisense; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Receptor, EphA2; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Tyrosine; Vanadates | 2002 |
Modulation of the ERG K+ current by the tyrosine phosphatase, SHP-1.
Topics: Animals; Blotting, Western; Cell Line; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Intracellular Signaling Peptides and Proteins; Patch-Clamp Techniques; Potassium Channels; Potassium Channels, Voltage-Gated; Precipitin Tests; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Rats; Recombinant Proteins; Vanadates | 2002 |
Sustained and dynamic inositol lipid metabolism inside and outside the immunological synapse.
Topics: Animals; Antigen Presentation; Antigens, Viral; Cell Division; Cell Polarity; Chromones; Enzyme Activation; Enzyme Inhibitors; Genes, Reporter; Green Fluorescent Proteins; H-2 Antigens; Histocompatibility Antigen H-2D; Humans; Luminescent Proteins; Lymphocyte Activation; Membrane Lipids; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microscopy, Confocal; Morpholines; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; T-Lymphocyte Subsets; Vanadates | 2002 |
Temporal pattern of NFkappaB activation influences apoptotic cell fate in a stimuli-dependent fashion.
Topics: Apoptosis; Base Sequence; Cell Lineage; DNA Primers; HeLa Cells; Humans; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; RNA, Antisense; Serine; Signal Transduction; Tumor Necrosis Factor-alpha; Tyrosine; Ultraviolet Rays; Vanadates | 2002 |
Nuclear phosphatases and the proteasome in suppression of STAT1 activity in hepatocytes.
Topics: Acetylcysteine; Cell Cycle Proteins; Complement C1 Inactivator Proteins; Complement C1 Inhibitor Protein; Cysteine Endopeptidases; DNA-Binding Proteins; Dual Specificity Phosphatase 1; Enzyme Inhibitors; Hepatocytes; Humans; Immediate-Early Proteins; Interferon-gamma; Multienzyme Complexes; Nuclear Proteins; Oligonucleotides; Phosphoprotein Phosphatases; Phosphorylation; Proteasome Endopeptidase Complex; Protein Binding; Protein Phosphatase 1; Protein Tyrosine Phosphatases; Recombinant Proteins; Serpins; Signal Transduction; STAT1 Transcription Factor; Staurosporine; Trans-Activators; Tumor Cells, Cultured; Ubiquitin; Vanadates | 2002 |
The chaperone protein 14-3-3 interacts with 3BP2/SH3BP2 and regulates its adapter function.
Topics: 14-3-3 Proteins; Amino Acid Motifs; Amino Acid Sequence; Animals; Blotting, Western; Carrier Proteins; Cell Line; Colforsin; COS Cells; Cytoplasm; Glutathione Transferase; Humans; Immunoblotting; Jurkat Cells; Ligands; Membrane Proteins; Microscopy, Confocal; Models, Biological; Molecular Sequence Data; Mutation; Phorbol Esters; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Kinase C; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Serine; Signal Transduction; Substrate Specificity; Time Factors; Transcription, Genetic; Transfection; Tumor Cells, Cultured; Two-Hybrid System Techniques; Tyrosine 3-Monooxygenase; U937 Cells; Vanadates | 2003 |
Interstitial lung disease in polymyositis and dermatomyositis.
Topics: Antibodies, Antinuclear; Biopsy; Blood Sedimentation; C-Reactive Protein; Dermatomyositis; Female; Humans; Lung Diseases, Interstitial; Male; Middle Aged; Polymyositis; Predictive Value of Tests; Pulmonary Fibrosis; Retrospective Studies; Risk Factors; Survival Analysis; Vanadates | 2002 |
Tyrosine phosphorylation of a novel 100-kDa protein coupled to CD28 in resting human T cells is enhanced by a signal through TCR/CD3 complex.
Topics: Calcimycin; CD28 Antigens; Enzyme Inhibitors; Humans; Immunoblotting; Jurkat Cells; Lymphocyte Activation; Naphthalenes; Phosphoproteins; Phosphorylation; Precipitin Tests; Receptors, Antigen, T-Cell; Signal Transduction; T-Lymphocytes; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 2003 |
Tyrosine phosphorylation of protein kinase D in the pleckstrin homology domain leads to activation.
Topics: Amino Acid Sequence; Blood Proteins; Blotting, Western; DNA; Enzyme Activation; Enzyme Inhibitors; HeLa Cells; Humans; Hydrogen Peroxide; Immunoblotting; Molecular Sequence Data; Mutation; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Structure, Tertiary; Recombinant Proteins; Signal Transduction; Time Factors; Transfection; Tyrosine; Vanadates | 2003 |
Two new substrates in insulin signaling, IRS5/DOK4 and IRS6/DOK5.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Animals; Blotting, Northern; Blotting, Western; Carrier Proteins; CHO Cells; Cricetinae; DNA, Complementary; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Humans; Insulin; Intracellular Signaling Peptides and Proteins; Kidney; Liver; MAP Kinase Signaling System; Molecular Sequence Data; Phosphoproteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Signal Transduction; src Homology Domains; Time Factors; Tissue Distribution; Transfection; Tyrosine; Vanadates | 2003 |
Activation of epidermal growth factor receptor is responsible for pervanadate-induced phospholipase D activation.
Topics: Animals; Cell Line; Enzyme Activation; ErbB Receptors; Fibroblasts; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phospholipase D; Rats; src-Family Kinases; Vanadates | 2003 |
Rac1 function is required for Src-induced transformation. Evidence of a role for Tiam1 and Vav2 in Rac activation by Src.
Topics: 3T3 Cells; Alleles; Animals; Binding Sites; Catalysis; Cell Line; Cell Transformation, Neoplastic; DNA; Enzyme Activation; Enzyme Inhibitors; Genes, Reporter; GTP Phosphohydrolases; Guanine Nucleotide Exchange Factors; Humans; Indoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Mutation; Oncogene Proteins; Phosphorylation; Plasmids; Promoter Regions, Genetic; Proteins; Proto-Oncogene Mas; Proto-Oncogene Proteins c-jun; Proto-Oncogene Proteins c-vav; Proto-Oncogene Proteins pp60(c-src); rac1 GTP-Binding Protein; Sulfonamides; T-Lymphoma Invasion and Metastasis-inducing Protein 1; Time Factors; Transfection; Tyrosine; Vanadates | 2003 |
PIAS proteins promote SUMO-1 conjugation to STAT1.
Topics: DNA-Binding Proteins; HeLa Cells; Humans; Interferon-gamma; Mutation; Protein Inhibitors of Activated STAT; Protein Processing, Post-Translational; Proteins; Signal Transduction; STAT1 Transcription Factor; SUMO-1 Protein; Trans-Activators; Transcriptional Activation; Vanadates | 2003 |
Radiosensitization by inhibition of IkappaB-alpha phosphorylation in human glioma cells.
Topics: Cell Survival; Cloning, Molecular; DNA Repair; Gene Expression Regulation, Neoplastic; Glioma; Humans; Leupeptins; Mutagenesis, Site-Directed; NF-kappa B; Phosphorylation; Radiation Tolerance; Transfection; Tumor Cells, Cultured; Vanadates | 2003 |
Cbl-mediated ubiquitinylation and negative regulation of Vav.
Topics: Animals; Cell Line; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Humans; Immunoblotting; Jurkat Cells; Luciferases; Mice; Mice, Transgenic; Models, Genetic; Mutation; Oncogene Protein v-cbl; Oncogene Proteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Mas; Proto-Oncogene Proteins c-vav; Retroviridae Proteins, Oncogenic; Signal Transduction; Time Factors; Transfection; Tyrosine; Ubiquitin; Vanadates | 2003 |
Modulation of VE-cadherin and PECAM-1 mediated cell-cell adhesions by mitogen-activated protein kinases.
Topics: Animals; Antigens, CD; Cadherins; Cell Adhesion; Cell Movement; Cell Size; Cells, Cultured; Collagen; Drug Combinations; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Laminin; Mice; Mitogen-Activated Protein Kinases; Neovascularization, Physiologic; Platelet Endothelial Cell Adhesion Molecule-1; Proteoglycans; src-Family Kinases; Tetradecanoylphorbol Acetate; Thrombospondin 1; Vanadates | 2003 |
Regulated cell surface pro-EGF ectodomain shedding is a zinc metalloprotease-dependent process.
Topics: ADAM Proteins; ADAM17 Protein; Animals; Calcium; Cell Membrane; CHO Cells; Cloning, Molecular; Cricetinae; DNA, Complementary; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; Epitopes; HeLa Cells; Humans; Ionophores; Kinetics; Metalloendopeptidases; Protein Kinase C; Protein Structure, Tertiary; Radioimmunoassay; Rats; Time Factors; Transfection; Tumor Necrosis Factor-alpha; Vanadates; Zinc | 2003 |
Immunoglobulin mu heavy chains do not mediate tyrosine phosphorylation of Ig alpha from the ER-cis-Golgi.
Topics: Animals; Antigens, CD; B-Lymphocyte Subsets; CD79 Antigens; Cell Line, Tumor; Clone Cells; Cytoplasm; Endoplasmic Reticulum; Enzyme Activation; Golgi Apparatus; Immunoglobulin Heavy Chains; Immunoglobulin mu-Chains; Mice; Phosphorylation; Protein Transport; Receptors, Antigen, B-Cell; Signal Transduction; src-Family Kinases; Stem Cells; Subcellular Fractions; Tyrosine; Vanadates | 2003 |
Tyrosine kinase p56lck regulates cell motility and nuclear factor kappaB-mediated secretion of urokinase type plasminogen activator through tyrosine phosphorylation of IkappaBalpha following hypoxia/reoxygenation.
Topics: Active Transport, Cell Nucleus; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Nucleus; DNA, Complementary; Enzyme Inhibitors; Genes, Reporter; Humans; Hydrogen Peroxide; Hypoxia; I-kappa B Proteins; Luciferases; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Microscopy, Fluorescence; Models, Biological; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidation-Reduction; Oxygen; Phosphorylation; Plasmids; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Serine; Signal Transduction; Time Factors; Transfection; Tyrosine; Urokinase-Type Plasminogen Activator; Vanadates | 2003 |
Tyrosine phosphorylation of rod cyclic nucleotide-gated channels switches off Ca2+/calmodulin inhibition.
Topics: Animals; Calcium; Calmodulin; Cattle; Cyclic Nucleotide-Gated Cation Channels; Eye Proteins; Ion Channel Gating; Ion Channels; Microinjections; Mutation; Oocytes; Patch-Clamp Techniques; Phosphorylation; Retinal Rod Photoreceptor Cells; RNA, Complementary; Tyrosine; Vanadates; Xenopus laevis | 2003 |
Calcium-dependent maintenance of agrin-induced postsynaptic specializations.
Topics: Acetylcholine; Agrin; Animals; Blotting, Western; Bungarotoxins; Calcium; Cells, Cultured; Chelating Agents; Chick Embryo; Dose-Response Relationship, Drug; Drug Interactions; Egtazic Acid; Enzyme Inhibitors; Extracellular Space; Fura-2; Intracellular Space; Muscle Fibers, Skeletal; Phosphorylation; Protein Binding; Rats; Receptor Aggregation; Receptor Protein-Tyrosine Kinases; Receptors, Cholinergic; Synapses; Time Factors; Vanadates; Vasodilator Agents | 2003 |
Tyrosine phosphatase inhibition induces loss of blood-brain barrier integrity by matrix metalloproteinase-dependent and -independent pathways.
Topics: Animals; Arsenicals; Blood-Brain Barrier; Blotting, Western; Brain; Cell Communication; Cells, Cultured; Electric Impedance; Electrophoresis; Endothelial Cells; Endothelium, Vascular; Enzyme Inhibitors; Immunohistochemistry; Matrix Metalloproteinases; Phosphorylation; Protein Tyrosine Phosphatases; Swine; Tight Junctions; Vanadates | 2004 |
The shedding of betaglycan is regulated by pervanadate and mediated by membrane type matrix metalloprotease-1.
Topics: Animals; Cell Membrane; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Enzyme Inhibitors; Gene Expression; Humans; Matrix Metalloproteinase 15; Matrix Metalloproteinase 16; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Peptide Fragments; Protein Tyrosine Phosphatases; Proteoglycans; Receptors, Transforming Growth Factor beta; Recombinant Proteins; Solubility; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Transfection; Transforming Growth Factor beta; Vanadates | 2004 |
Relationship between phosphatase activity and cytotoxic effect of two protein phosphatase inhibitors, okadaic acid and pervanadate, on human myeloid leukemia cell line.
Topics: Cell Survival; Enzyme Inhibitors; HL-60 Cells; Humans; Molecular Structure; Nitrophenols; Okadaic Acid; Organophosphorus Compounds; Phosphoprotein Phosphatases; Vanadates | 2003 |
Expression and activation of signal regulatory protein alpha on astrocytomas.
Topics: Antigens, Differentiation; Astrocytoma; Base Sequence; Brain Neoplasms; DNA Primers; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glycosylation; Humans; Immunohistochemistry; Membrane Glycoproteins; Molecular Sequence Data; Neural Cell Adhesion Molecule L1; Receptors, Immunologic; Recombinant Fusion Proteins; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Vanadates | 2004 |
Requirement of protein tyrosine kinase and phosphatase activities for human sperm exocytosis.
Topics: Acrosome; Acrosome Reaction; Animals; Calcium; Humans; Male; Mice; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; rab3A GTP-Binding Protein; Spermatozoa; Vanadates | 2004 |
Pervanadate-induced reverse translocation and tyrosine phosphorylation of phorbol ester-stimulated protein kinase C betaII are mediated by Src-family tyrosine kinases in porcine neutrophils.
Topics: Animals; Cell Membrane; Cytosol; Enzyme Activation; Enzyme Inhibitors; Immunoblotting; Neutrophils; Phosphorylation; Precipitin Tests; Protein Kinase C; Protein Kinase C beta; Protein Transport; Protein Tyrosine Phosphatases; Pyrimidines; src-Family Kinases; Swine; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 2004 |
Preferential oxidation of the second phosphatase domain of receptor-like PTP-alpha revealed by an antibody against oxidized protein tyrosine phosphatases.
Topics: Alkylation; Amino Acid Sequence; Animals; Antibodies; Antibody Specificity; Becaplermin; Binding Sites; Cell Line; Humans; Hydrogen Peroxide; Iodoacetic Acid; Mice; Molecular Sequence Data; Oxidation-Reduction; Platelet-Derived Growth Factor; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-sis; Ultraviolet Rays; Vanadates | 2004 |
The cytoplasmic domain of CEACAM1-L controls its lateral localization and the organization of desmosomes in polarized epithelial cells.
Topics: Amino Acid Sequence; Amino Acids; Androstadienes; Animals; Antigens, CD; Antigens, Differentiation; Binding Sites; Carcinoembryonic Antigen; Cell Adhesion Molecules; Cell Line; Cell Polarity; Cytoplasm; Desmosomes; Dogs; Epithelial Cells; Mice; Microscopy, Confocal; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Isoforms; Protein Structure, Tertiary; Rats; Recombinant Proteins; Sequence Deletion; Staurosporine; Vanadates; Wortmannin | 2004 |
Tyrosine phosphorylation-dependent activation of NFkappaB is compromised in T cells from the elderly.
Topics: Adult; Aged; Aged, 80 and over; Aging; Enzyme Inhibitors; Humans; Hydrogen Peroxide; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Protein Tyrosine Phosphatases; T-Lymphocytes; Tyrosine; Vanadates | 2004 |
T cell receptor engagement leads to phosphorylation of clathrin heavy chain during receptor internalization.
Topics: CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line; Clathrin Heavy Chains; Endocytosis; Humans; Jurkat Cells; Kinetics; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Phosphorylation; Receptors, Antigen, T-Cell; Signal Transduction; Vanadates | 2004 |
The mouse homologue of the leukocyte-associated Ig-like receptor-1 is an inhibitory receptor that recruits Src homology region 2-containing protein tyrosine phosphatase (SHP)-2, but not SHP-1.
Topics: Amino Acid Sequence; Animals; Cell Line; Cell Line, Transformed; Cell Line, Tumor; Cytoplasm; Down-Regulation; HT29 Cells; Humans; Intracellular Signaling Peptides and Proteins; Ligands; Lymphoid Tissue; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Molecular Sequence Data; Multigene Family; Protein Binding; Protein Phosphatase 1; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Immunologic; SH2 Domain-Containing Protein Tyrosine Phosphatases; src Homology Domains; Synteny; Vanadates | 2004 |
MT1-MMP mediates MUC1 shedding independent of TACE/ADAM17.
Topics: ADAM Proteins; ADAM17 Protein; Cell Line; Endometrium; Enzyme Inhibitors; Epithelial Cells; Female; Humans; Hydrolysis; Luteal Phase; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Mucin-1; Tumor Necrosis Factor-alpha; Uterus; Vanadates | 2004 |
B-cell signal transduction: tyrosine phosphorylation, kinase activity, and calcium mobilization.
Topics: Animals; B-Lymphocytes; Calcium Signaling; Chickens; Child, Preschool; Enzyme Inhibitors; Flow Cytometry; Herpesvirus 4, Human; Humans; Male; Mice; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein-Tyrosine Kinases; Receptors, Antigen, B-Cell; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 2004 |
Endocytosis as a mechanism for tyrosine kinase-dependent suppression of a voltage-gated potassium channel.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Carbachol; Cell Line; Dynamins; Endocytosis; Humans; In Vitro Techniques; Kv1.2 Potassium Channel; Mutagenesis, Site-Directed; Potassium Channels, Voltage-Gated; Protein-Tyrosine Kinases; Rats; Recombinant Proteins; Transfection; Vanadates | 2004 |
Role of tyrosine phosphorylation in the regulation of cleavage secretion of angiotensin-converting enzyme.
Topics: Animals; Carcinogens; Cell Line; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Enzyme Inhibitors; Heat-Shock Proteins; Kidney; Mass Spectrometry; Mice; Mitogen-Activated Protein Kinases; Molecular Chaperones; p38 Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Structure, Tertiary; Tetradecanoylphorbol Acetate; Tyrosine; Vanadates | 2004 |
Identification of a PKB/Akt hydrophobic motif Ser-473 kinase as DNA-dependent protein kinase.
Topics: 3T3-L1 Cells; Amino Acid Motifs; Animals; Cell Line; Cell Line, Tumor; Cell Membrane; Chromatography, Gel; DNA-Activated Protein Kinase; DNA-Binding Proteins; DNA, Complementary; Enzyme Activation; Genetic Complementation Test; Glioblastoma; Humans; Insulin; Mice; Microscopy, Fluorescence; Models, Biological; Nuclear Proteins; Phosphorylation; Plasmids; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Proteins; Serine; Time Factors; Transfection; Vanadates | 2004 |
Negative regulation of T cell receptor signaling by Siglec-7 (p70/AIRM) and Siglec-9.
Topics: Amino Acid Motifs; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Blotting, Western; Cell Separation; Cytoplasm; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Genes, Reporter; Humans; Immunoprecipitation; Jurkat Cells; Lectins; Ligands; Luciferases; Microscopy, Fluorescence; Models, Biological; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Sialic Acid Binding Ig-like Lectin 3; Sialic Acid Binding Immunoglobulin-like Lectins; Signal Transduction; T-Lymphocytes; Time Factors; Transcription, Genetic; Transcriptional Activation; Transfection; Tyrosine; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 2004 |
H2O2-induced intermolecular disulfide bond formation between receptor protein-tyrosine phosphatases.
Topics: Animals; Catalysis; Coloring Agents; COS Cells; Cysteine; Dimerization; Disulfides; Dithiothreitol; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Genetic Vectors; Humans; Hydrogen Peroxide; Immunoprecipitation; Mutation; Oxidation-Reduction; Oxygen; Protein Conformation; Protein Folding; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptors, Cell Surface; Time Factors; Transfection; Vanadates | 2004 |
Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.
Topics: Adaptor Proteins, Signal Transducing; Adenoma; Adenomatous Polyposis Coli Protein; Alleles; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Line; Clathrin; Colorectal Neoplasms; Cyclooxygenase 2; Dinoprostone; Disease Progression; Enterocytes; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Genes, APC; HeLa Cells; Humans; Immunoblotting; Immunohistochemistry; Immunoprecipitation; Intestinal Mucosa; Intestine, Small; Isoenzymes; Jurkat Cells; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Biological; Mutation; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Prostaglandin-Endoperoxide Synthases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recurrence; Signal Transduction; src-Family Kinases; Tissue Distribution; Transcriptional Activation; Tyrosine; Ubiquitin; Up-Regulation; Vanadates | 2004 |
Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeleton.
Topics: Animals; Chlorocebus aethiops; COS Cells; Cytoskeleton; Cytosol; Golgi Apparatus; Guanine Nucleotide-Releasing Factor 2; HeLa Cells; Humans; Microscopy, Fluorescence; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-hck; Proto-Oncogene Proteins pp60(c-src); Recombinant Fusion Proteins; Structure-Activity Relationship; Subcellular Fractions; Vanadates | 2004 |
c-Cbl binds to tyrosine-phosphorylated neurotrophin receptor p75 and induces its ubiquitination.
Topics: Amino Acid Sequence; Binding Sites; Cell Line; Humans; Phosphorylation; Protein Binding; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptor, Nerve Growth Factor; Receptors, Nerve Growth Factor; Signal Transduction; Tyrosine; Ubiquitin; Ubiquitin-Protein Ligases; Vanadates | 2004 |
alpha-thrombin rapidly induces tyrosine phosphorylation of a novel, 74-78-kDa stress response protein(s) in lung fibroblast cells.
Topics: Animals; Blotting, Western; Cell Line; Cricetinae; Cytokines; Cytoplasm; DNA-Binding Proteins; Enzyme Inhibitors; Fibroblasts; Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Immunoprecipitation; Interleukin-6; Lung; Mass Spectrometry; Membrane Proteins; Peptide Fragments; Peptides; Phosphorylation; Protein Binding; STAT3 Transcription Factor; Subcellular Fractions; Thrombin; Time Factors; Trans-Activators; Tyrosine; Vanadates | 2004 |
The magnitude of Akt/phosphatidylinositol 3'-kinase proliferating signaling is related to CD45 expression in human myeloma cells.
Topics: Androstadienes; Cell Division; Cell Line, Tumor; G1 Phase; Humans; Insulin-Like Growth Factor I; Leukocyte Common Antigens; Multiple Myeloma; Phosphatidylinositol 3-Kinases; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, IGF Type 1; Signal Transduction; Vanadates; Wortmannin | 2004 |
Recruitment of C-terminal Src kinase by the leukocyte inhibitory receptor CD85j.
Topics: Amino Acid Motifs; Animals; Antigens, CD; B-Lymphocytes; beta-Galactosidase; Blotting, Western; CSK Tyrosine-Protein Kinase; Cytoplasm; DNA; DNA Mutational Analysis; DNA, Complementary; Humans; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Jurkat Cells; Leukocyte Immunoglobulin-like Receptor B1; Peptides; Phosphorylation; Phosphotransferases; Protein Binding; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Immunologic; src-Family Kinases; Transfection; Two-Hybrid System Techniques; Tyrosine; Vanadates | 2004 |
Normal neutrophil maturation is associated with selective loss of MAP kinase activation by G-CSF.
Topics: Cell Differentiation; Down-Regulation; Enzyme Activation; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Mitogen-Activated Protein Kinases; Neutrophils; p38 Mitogen-Activated Protein Kinases; Protein Tyrosine Phosphatases; Signal Transduction; Vanadates | 2005 |
FLT3/ITD mutation signaling includes suppression of SHP-1.
Topics: Acute Disease; Carbazoles; Cell Line, Tumor; Cell Proliferation; Cell Survival; Down-Regulation; fms-Like Tyrosine Kinase 3; Furans; Humans; Hydrolysis; Indoles; Intracellular Signaling Peptides and Proteins; Leukemia, Myeloid; Mutation; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; RNA Interference; RNA, Messenger; RNA, Neoplasm; Signal Transduction; Vanadates | 2005 |
Human Ran cysteine 112 oxidation by pervanadate regulates its binding to keratins.
Topics: Actins; Cell Line, Tumor; Cell Movement; Cell Survival; Cell-Free System; Cysteine; DNA, Complementary; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Humans; Immunoprecipitation; Keratins; Mass Spectrometry; Models, Biological; Mutation; Oxygen; Phosphorylation; Proteasome Inhibitors; Protein Binding; Proteomics; ran GTP-Binding Protein; Tyrosine; Vanadates | 2005 |
Carnosol inhibits beta-catenin tyrosine phosphorylation and prevents adenoma formation in the C57BL/6J/Min/+ (Min/+) mouse.
Topics: Abietanes; Adenoma; Animals; beta Catenin; Cadherins; Cell Adhesion; Cell Membrane; Colonic Neoplasms; Cytoskeletal Proteins; Enterocytes; Female; Intestine, Small; Mice; Mice, Inbred C57BL; Phenanthrenes; Phosphorylation; Rosmarinus; Trans-Activators; Tyrosine; Vanadates | 2005 |
Tyrosine phosphatase regulation of MuSK-dependent acetylcholine receptor clustering.
Topics: Agrin; Animals; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Intracellular Signaling Peptides and Proteins; Mice; Muscle Fibers, Skeletal; Muscle, Skeletal; Neuromuscular Junction; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Receptor Aggregation; Receptor Protein-Tyrosine Kinases; Receptors, Cholinergic; Synaptic Transmission; Vanadates; Xenopus | 2005 |
LAR receptor protein tyrosine phosphatases in the development and maintenance of excitatory synapses.
Topics: Adaptor Proteins, Signal Transducing; Animals; Animals, Newborn; beta Catenin; Blotting, Western; Brain; Cells, Cultured; Chlorocebus aethiops; COS Cells; Cytoskeletal Proteins; Dendrites; Diagnostic Imaging; Enzyme Inhibitors; Excitatory Postsynaptic Potentials; Gene Expression Regulation, Developmental; Genistein; Green Fluorescent Proteins; Hippocampus; Humans; Immunohistochemistry; Immunoprecipitation; Membrane Potentials; Molecular Sequence Data; Mutagenesis; Nerve Tissue Proteins; Neurons; Patch-Clamp Techniques; Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase; Phosphoproteins; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-myc; Rats; Receptor-Like Protein Tyrosine Phosphatases, Class 2; Receptors, AMPA; Receptors, Cell Surface; Receptors, N-Methyl-D-Aspartate; RNA, Antisense; RNA, Small Interfering; Synapses; Time Factors; Trans-Activators; Transfection; Tyrosine; Vanadates | 2005 |
Constitutive secretion of serum albumin requires reversible protein tyrosine phosphorylation events in trans-Golgi.
Topics: Animals; Biomarkers; Cells, Cultured; Enzyme Inhibitors; Genistein; Hepatocytes; Male; Phosphoprotein Phosphatases; Phosphorylation; Protein Transport; Protein-Tyrosine Kinases; Rats; Serum Albumin; Substrate Specificity; trans-Golgi Network; Tyrosine; Vanadates | 2005 |
Two-stage affinity purification for inducibly phosphorylated membrane proteins.
Topics: Animals; Antibodies; Biotinylation; Cell Compartmentation; Cell Line; Electrophoresis, Polyacrylamide Gel; Hybridomas; Immunoprecipitation; Isoelectric Focusing; Macrophages; Mass Spectrometry; Membrane Proteins; Mice; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Proteome; T-Lymphocytes; Vanadates | 2005 |
Imaging epidermal growth factor receptor phosphorylation in human colorectal cancer cells and human tissues.
Topics: Cell Line, Tumor; Cell Proliferation; Cloning, Molecular; Colorectal Neoplasms; Culture Media, Serum-Free; DNA, Complementary; Enzyme-Linked Immunosorbent Assay; ErbB Receptors; Fluorescence Resonance Energy Transfer; Humans; Immunoblotting; Immunoprecipitation; Kinetics; Microscopy, Confocal; Microscopy, Fluorescence; Phosphorylation; Phosphotyrosine; Receptor Protein-Tyrosine Kinases; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Time Factors; Vanadates | 2005 |
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase.
Topics: Aged, 80 and over; Alzheimer Disease; Amino Acid Sequence; Amino Acid Substitution; Animals; Brain; Brain Chemistry; Cell Line, Tumor; Chlorocebus aethiops; CHO Cells; COS Cells; Cricetinae; Cricetulus; Female; Fetal Proteins; Humans; Mass Spectrometry; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Neuroblastoma; Neurofibrillary Tangles; Neurons; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-abl; Proto-Oncogene Proteins c-fyn; src-Family Kinases; tau Proteins; Transfection; Vanadates | 2005 |
Reactive oxygen species induce tyrosine phosphorylation of and Src kinase recruitment to NO-sensitive guanylyl cyclase.
Topics: Animals; Aorta; Blotting, Western; Chlorocebus aethiops; COS Cells; Enzyme Inhibitors; Glutathione Transferase; Guanylate Cyclase; Humans; Hydrogen Peroxide; Muscle, Smooth, Vascular; Nitric Oxide; PC12 Cells; Phosphorylation; Precipitin Tests; Rats; Rats, Wistar; Reactive Oxygen Species; Recombinant Fusion Proteins; Solubility; src-Family Kinases; Tyrosine; Vanadates; Vanadium Compounds | 2005 |
Effector-induced Syk-mediated phosphorylation in human erythrocytes.
Topics: Anion Exchange Protein 1, Erythrocyte; Cytoskeleton; Diamide; Enzyme Precursors; Erythrocytes; Ethylmaleimide; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Luminescent Measurements; Oxidation-Reduction; Phosphorylation; Protein-Tyrosine Kinases; src-Family Kinases; Syk Kinase; Vanadates | 2005 |
Oligomerization-induced differential dephosphorylation of c-Met receptor tyrosine kinase.
Topics: Animals; Chlorocebus aethiops; Enzyme Inhibitors; Gene Expression; Homeostasis; Humans; Ligands; Mice; Multiprotein Complexes; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-met; Signal Transduction; Vanadates; Vero Cells | 2005 |
Src-mediated phosphorylation regulates subcellular distribution and activity of human inducible nitric oxide synthase.
Topics: Amino Acid Sequence; Cells, Cultured; Enzyme Inhibitors; Epithelial Cells; Humans; Immunoblotting; Immunoprecipitation; Intestinal Mucosa; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Nitric Oxide; Nitric Oxide Synthase Type II; Phosphorylation; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins pp60(c-src); Sequence Homology, Amino Acid; Subcellular Fractions; Transfection; Tyrosine; Vanadates | 2006 |
Tyrosine phosphatase SHP-2 regulates IL-1 signaling in fibroblasts through focal adhesions.
Topics: Actinin; Adaptor Proteins, Signal Transducing; Animals; Cell Line; Cells, Cultured; Collagen; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibronectins; Focal Adhesions; Humans; Interleukin-1; Intracellular Signaling Peptides and Proteins; Mice; Mutation; Paxillin; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; RNA, Small Interfering; Signal Transduction; Transfection; Tyrosine; Vanadates | 2006 |
Tyrosine phosphorylation and the small GTPase rac cross-talk in regulation of endothelial barrier function.
Topics: Actins; Adherens Junctions; Antigens, CD; Cadherins; Capillary Permeability; Cell Communication; Cells, Cultured; Dose-Response Relationship, Drug; Electric Impedance; Endothelial Cells; Genes, Reporter; Green Fluorescent Proteins; Humans; Phosphorylation; Protein Tyrosine Phosphatases; rac1 GTP-Binding Protein; Time Factors; Transfection; Tyrosine; Vanadates; Vascular Endothelial Growth Factors | 2005 |
NCAM140 stimulates integrin-dependent cell migration by ectodomain shedding.
Topics: Animals; Blotting, Western; Cell Adhesion; Cell Adhesion Molecules, Neuronal; Cell Line, Tumor; Cell Membrane; Cell Movement; Cells, Cultured; Cytoplasm; Dipeptides; Enzyme Inhibitors; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Integrins; Metalloproteases; Protease Inhibitors; Protein Tyrosine Phosphatases; Rats; Transfection; Vanadates | 2005 |
NGF rapidly increases membrane expression of TRPV1 heat-gated ion channels.
Topics: Amino Acid Sequence; Animals; Calcium; Capsaicin; Cell Line; Cells, Cultured; DNA; DNA, Complementary; Electrophysiology; Gene Expression Regulation; Glutathione Transferase; Hot Temperature; Humans; Immunoblotting; Immunohistochemistry; Ion Channels; Mice; Models, Biological; Molecular Sequence Data; Mutation; Nerve Growth Factor; Neurons; Phosphatidylinositol 3-Kinases; Phosphorylation; Plasmids; Protein Binding; Receptor, trkA; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Signal Transduction; Sodium; src-Family Kinases; Time Factors; Transfection; TRPV Cation Channels; Tyrosine; Vanadates | 2005 |
Bispecific and human disease-related anti-keratin rabbit monoclonal antibodies.
Topics: Animals; Antibodies, Bispecific; Antibodies, Monoclonal; Brain; Brain Chemistry; Cell Line; Colonic Neoplasms; Cricetinae; Enzyme Inhibitors; Epitopes; HT29 Cells; Humans; Immunoblotting; Immunohistochemistry; Keratin-18; Keratin-8; Keratins; Kidney; Liver; Liver Diseases; Mice; Mutation; Okadaic Acid; Phosphorylation; Rabbits; Serine; Stomach Neoplasms; Transfection; Vaccination; Vanadates | 2006 |
A specific mechanomodulatory role for p38 MAPK in embryonic joint articular surface cell MEK-ERK pathway regulation.
Topics: Animals; Anti-Inflammatory Agents; Blotting, Western; Cell Membrane; Chick Embryo; Densitometry; Dose-Response Relationship, Drug; Erythrocytes; Extracellular Signal-Regulated MAP Kinases; Fibroblast Growth Factor 2; Gene Expression Regulation, Enzymologic; Hyaluronic Acid; Imidazoles; Immunoblotting; Immunochemistry; Immunoprecipitation; Joints; MAP Kinase Signaling System; Models, Biological; Models, Statistical; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins c-fos; Pyridines; Signal Transduction; Stress, Mechanical; Threonine; Time Factors; Vanadates | 2006 |
Restoration of SHIP-1 activity in human leukemic cells modifies NF-kappaB activation pathway and cellular survival upon oxidative stress.
Topics: Apoptosis; Blotting, Western; Cell Survival; Flow Cytometry; Genetic Complementation Test; Humans; Hydrogen Peroxide; I-kappa B Kinase; I-kappa B Proteins; Inositol Polyphosphate 5-Phosphatases; Jurkat Cells; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases; Phosphoric Monoester Hydrolases; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Tumor Necrosis Factor-alpha; Vanadates | 2006 |
B and T lymphocyte attenuator-mediated signal transduction provides a potent inhibitory signal to primary human CD4 T cells that can be initiated by multiple phosphotyrosine motifs.
Topics: Amino Acid Motifs; Animals; CD28 Antigens; CD4-Positive T-Lymphocytes; Cell Proliferation; Dimerization; Growth Inhibitors; Humans; Interleukin-2; Intracellular Signaling Peptides and Proteins; Lymphocyte Activation; Mice; Mutation; Phosphotyrosine; Protein Transport; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Receptors, Immunologic; Recombinant Fusion Proteins; Signal Transduction; Vanadates | 2006 |
[The role of protein tyrosine phosphatases Shp-2 involved in the formation of the neuromuscular junction].
Topics: Agrin; Animals; Blotting, Western; Cell Line; Enzyme Inhibitors; Mice; Muscle Fibers, Skeletal; Myoblasts; Neuromuscular Junction; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Receptors, Cholinergic; RNA Interference; Signal Transduction; Vanadates | 2006 |
Redox regulation of CD21 shedding involves signaling via PKC and indicates the formation of a juxtamembrane stalk.
Topics: Amino Acid Sequence; Antioxidants; Cell Membrane; Cells, Cultured; Cysteine; Disulfides; Epithelial Cells; Humans; Ionomycin; Metalloproteases; Models, Biological; Molecular Sequence Data; Oxidation-Reduction; Protein Kinase C; Protein Processing, Post-Translational; Receptors, Complement 3d; Serine Endopeptidases; Signal Transduction; Sulfhydryl Compounds; Tetradecanoylphorbol Acetate; Vanadates | 2006 |
The dynamics of recycled acetylcholine receptors at the neuromuscular junction in vivo.
Topics: Animals; Arsenicals; Female; Mice; Microscopy, Confocal; Neuromuscular Junction; Protein Transport; Protein Tyrosine Phosphatases; Receptors, Nicotinic; Synapses; Vanadates | 2006 |
Spred-2 steady-state levels are regulated by phosphorylation and Cbl-mediated ubiquitination.
Topics: Adaptor Proteins, Signal Transducing; Cells, Cultured; Epidermal Growth Factor; Humans; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-cbl; Repressor Proteins; RNA Interference; Tyrosine; Ubiquitin; Vanadates | 2006 |
Bruton's tyrosine kinase prevents activation of the anti-apoptotic transcription factor STAT3 and promotes apoptosis in neoplastic B-cells and B-cell precursors exposed to oxidative stress.
Topics: Agammaglobulinaemia Tyrosine Kinase; Animals; Apoptosis; Chickens; Enzyme Inhibitors; Female; Humans; Leukemia, B-Cell; Lymphoma, B-Cell; Neoplasm Proteins; Oxidative Stress; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Recombinant Proteins; STAT3 Transcription Factor; Tumor Cells, Cultured; Vanadates | 2007 |
Histone deacetylase inhibitor trichostatin A sustains sodium pervanadate-induced NF-kappaB activation by delaying IkappaBalpha mRNA resynthesis: comparison with tumor necrosis factor alpha.
Topics: Acetylation; Enzyme Inhibitors; HeLa Cells; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; I-kappa B Proteins; Intercellular Adhesion Molecule-1; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Promoter Regions, Genetic; Protein Binding; RNA Polymerase II; RNA, Messenger; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor-alpha; Vanadates | 2007 |
Studies of a germinal centre B-cell expressed gene, GCET2, suggest its role as a membrane associated adapter protein.
Topics: Adaptor Proteins, Signal Transducing; Animals; B-Lymphocytes; Base Sequence; Binding Sites; Cell Line, Tumor; Cell Membrane; Chlorocebus aethiops; COS Cells; Germinal Center; GRB2 Adaptor Protein; Humans; Immunoblotting; Intracellular Signaling Peptides and Proteins; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Mice; Microfilament Proteins; Microscopy, Confocal; Molecular Sequence Data; Mutagenesis, Site-Directed; Neoplasm Proteins; Phosphorylation; Protein-Tyrosine Kinases; Sequence Alignment; Transduction, Genetic; Transfection; Vanadates | 2007 |
Quantitation of multisite EGF receptor phosphorylation using mass spectrometry and a novel normalization approach.
Topics: Amino Acid Sequence; Cell Adhesion; Enzyme Inhibitors; ErbB Receptors; HeLa Cells; Humans; Isotope Labeling; Mass Spectrometry; Molecular Sequence Data; Phosphopeptides; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Tyrosine; Vanadates | 2007 |
Internalization of caveolae and their relationship with endosomes in cultured human and mouse endothelial cells.
Topics: Animals; Biological Transport; Blotting, Western; Caveolin 1; Cells, Cultured; Endosomes; Endothelial Cells; Humans; Immunohistochemistry; Immunoprecipitation; Mice; Microscopy, Electron; Microscopy, Fluorescence; Phosphorylation; rab4 GTP-Binding Proteins; rab5 GTP-Binding Proteins; Umbilical Veins; Vanadates | 2007 |
Regulation of airway goblet cell mucin secretion by tyrosine phosphorylation signaling pathways.
Topics: Adenosine Triphosphate; Cells, Cultured; Epithelial Cells; Estrenes; Genistein; Goblet Cells; Humans; Mucins; Phosphorylation; Phosphotyrosine; Protein Kinase C-delta; Protein Kinase Inhibitors; Pyrrolidinones; Respiratory System; Signal Transduction; Time Factors; Type C Phospholipases; Vanadates | 2007 |
Increased prevalence of Borrelia burgdorferi infections in Bernese Mountain Dogs: a possible breed predisposition.
Topics: Animals; Antibodies, Bacterial; Bacterial Vaccines; Borrelia burgdorferi; Dog Diseases; Dogs; Female; Genetic Predisposition to Disease; Lyme Disease; Male; Prevalence; Switzerland; Vanadates | 2007 |
Preformed STAT3 transducer complexes in human HepG2 cells and rat hepatocytes.
Topics: Actins; Animals; Caveolins; Cell Line, Tumor; Cell Membrane; Cell Separation; Cholesterol; Cytoskeleton; Detergents; Hepatocytes; Humans; Interleukin-6; Male; Multiprotein Complexes; Phosphotyrosine; Rats; Signal Transduction; Solubility; STAT3 Transcription Factor; Subcellular Fractions; Tubulin; Vanadates | 2007 |
c-Cbl is not required for ERK1/2-dependent degradation of BimEL.
Topics: Animals; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; Cell Line; Enzyme Inhibitors; Epidermal Growth Factor; Epithelial Cells; Fibroblasts; Humans; Membrane Proteins; Mice; Mice, Knockout; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mutation; Phosphorylation; Proteasome Endopeptidase Complex; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Serine; Tamoxifen; Tyrosine; Ubiquitin; Vanadates | 2007 |
Shedding of the urinary biomarker kidney injury molecule-1 (KIM-1) is regulated by MAP kinases and juxtamembrane region.
Topics: Animals; Antioxidants; Biomarkers; Cell Line, Tumor; Cell Membrane; Chlorocebus aethiops; COS Cells; Dipeptides; Hepatitis A Virus Cellular Receptor 1; Humans; MAP Kinase Signaling System; Membrane Glycoproteins; Metalloendopeptidases; Mitogen-Activated Protein Kinases; Phenylmercury Compounds; Phosphorylation; Protein Isoforms; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Pyrrolidines; Receptors, Virus; Thiocarbamates; Vanadates | 2007 |
Phosphorylated ITIMs enable ubiquitylation of an inhibitory cell surface receptor.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Cell Line; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Endocytosis; Enzyme Inhibitors; HL-60 Cells; Humans; Jurkat Cells; Lysine; Mice; Phosphorylation; Protein Binding; Proto-Oncogene Proteins c-cbl; Proto-Oncogene Proteins c-fyn; Recombinant Fusion Proteins; RNA, Small Interfering; Sialic Acid Binding Ig-like Lectin 3; Transfection; Ubiquitin; Ubiquitination; Vanadates | 2008 |
Characterization of the chicken CD200 receptor family.
Topics: Alternative Splicing; Amino Acid Sequence; Animals; Antigens, CD; Base Sequence; Cell Line; Chickens; Chromosomes; Genome; Glycosylation; Humans; Molecular Sequence Data; Molecular Weight; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Homology, Amino Acid; Solubility; Tyrosine; Vanadates | 2008 |
The ALCAM shedding by the metalloprotease ADAM17/TACE is involved in motility of ovarian carcinoma cells.
Topics: ADAM Proteins; ADAM17 Protein; Antigens, CD; Ascitic Fluid; Carcinogens; Cell Adhesion; Cell Adhesion Molecules, Neuronal; Cell Line, Tumor; Cell Movement; Culture Media, Conditioned; Enzyme Activation; Enzyme Inhibitors; Female; Fetal Proteins; Humans; Neoplasm Invasiveness; Ovarian Neoplasms; RNA, Small Interfering; Solubility; Tetradecanoylphorbol Acetate; Vanadates | 2007 |
Engagement of phospholipid scramblase 1 in activated cells: implication for phosphatidylserine externalization and exocytosis.
Topics: Animals; Calcimycin; Cell Line, Tumor; Cell Membrane; Detergents; Enzyme Inhibitors; Exocytosis; Ionophores; Microscopy, Confocal; Models, Biological; Phosphatidylserines; Phospholipid Transfer Proteins; Phosphorylation; Rats; Tyrosine; Vanadates | 2008 |
Modulation of murine complement receptor type 2 (CR2/CD21) ectodomain shedding by its cytoplasmic domain.
Topics: Amino Acid Sequence; Animals; Antioxidants; B-Lymphocytes; Cytoplasm; Fluorescence; Male; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Structure, Tertiary; Receptors, Complement 3d; Sequence Deletion; Sulfhydryl Compounds; Time Factors; Vanadates | 2008 |
Allosteric inhibition of the nonMyristoylated c-Abl tyrosine kinase by phosphopeptides derived from Abi1/Hssh3bp1.
Topics: Adaptor Proteins, Signal Transducing; Allosteric Regulation; Amino Acid Sequence; Animals; Binding Sites; Cell Line; Cytoskeletal Proteins; Enzyme Inhibitors; Ligands; Molecular Sequence Data; Phosphopeptides; Proto-Oncogene Proteins c-abl; src Homology Domains; Tyrosine; Vanadates | 2008 |
Pervanadate-induced shedding of the intercellular adhesion molecule (ICAM)-1 ectodomain is mediated by membrane type-1 matrix metalloproteinase (MT1-MMP).
Topics: Cells, Cultured; Humans; Intercellular Adhesion Molecule-1; Matrix Metalloproteinase 14; Matrix Metalloproteinase Inhibitors; Protein Processing, Post-Translational; Protein Structure, Tertiary; RNA, Small Interfering; Substrate Specificity; Tissue Distribution; Tissue Inhibitor of Metalloproteinases; Vanadates | 2008 |
Geldanamycin inhibits tyrosine phosphorylation-dependent NF-kappaB activation.
Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; DNA; Gene Expression Regulation; Genes, src; HeLa Cells; HSP90 Heat-Shock Proteins; Humans; I-kappa B Kinase; Jurkat Cells; Lactams, Macrocyclic; Molecular Structure; NF-kappa B; Phosphorylation; Protein Binding; RNA, Messenger; Tyrosine; Vanadates | 2008 |
Tyr-phosphorylation signals translocate RIN3, the small GTPase Rab5-GEF, to early endocytic vesicles.
Topics: Carrier Proteins; Cytoplasm; Enzyme Inhibitors; Guanine Nucleotide Exchange Factors; HeLa Cells; Humans; Phosphorylation; Protein Conformation; Protein Structure, Tertiary; Protein Transport; Protein Tyrosine Phosphatases; rab5 GTP-Binding Proteins; Sequence Deletion; Transport Vesicles; Tyrosine; Vanadates | 2008 |
Involvement of Src tyrosine kinases (SFKs) and of focal adhesion kinase (FAK) in the injurious mechanism in rat primary neuronal cultures exposed to chemical ischemia.
Topics: Animals; Apoptosis; Brain Ischemia; Cells, Cultured; Enzyme Inhibitors; Focal Adhesion Kinase 1; Iodoacetic Acid; L-Lactate Dehydrogenase; Neurons; Phosphorylation; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins c-yes; Proto-Oncogene Proteins pp60(c-src); Rats; Reactive Oxygen Species; Signal Transduction; src-Family Kinases; Vanadates | 2009 |
Phosphorylation and ankyrin-G binding of the C-terminal domain regulate targeting and function of the ammonium transporter RhBG.
Topics: Amino Acid Substitution; Ammonia; Animals; Ankyrins; Cation Transport Proteins; Cell Line; Cell Membrane; Cell Polarity; Cytoskeleton; Dogs; Enzyme Inhibitors; Epithelial Cells; Glycoproteins; Humans; Intracellular Signaling Peptides and Proteins; Ion Transport; Membrane Transport Proteins; Mice; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Spectrin; src-Family Kinases; Syk Kinase; Vanadates | 2008 |
Shedding of epidermal growth factor receptor is a regulated process that occurs with overexpression in malignant cells.
Topics: Amino Acid Sequence; Animals; Cattle; Cell Line, Tumor; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; Molecular Sequence Data; Neoplasms; Peptides; Phenylmercuric Acetate; Protease Inhibitors; Protein Isoforms; Protein Kinase C; Protein Structure, Tertiary; Sequence Alignment; Spectrometry, Mass, Electrospray Ionization; Tetradecanoylphorbol Acetate; Transforming Growth Factor alpha; Vanadates | 2008 |
Human kidney anion exchanger 1 localisation in MDCK cells is controlled by the phosphorylation status of two critical tyrosines.
Topics: Acid-Base Equilibrium; Amino Acid Substitution; Animals; Anion Exchange Protein 1, Erythrocyte; Bicarbonates; Buffers; Cell Line; Cell Membrane; Dogs; Enzyme Inhibitors; Humans; Kidney; Mutation, Missense; Phosphorylation; Protein Structure, Tertiary; Protein Transport; Tyrosine; Vanadates | 2008 |
Quantitative phosphoproteome analysis of a mouse liver cell line reveals specificity of phosphatase inhibitors.
Topics: Animals; Cell Line, Tumor; Chromatography, Liquid; Computational Biology; Hepatocytes; Insulin; Liver; Marine Toxins; Mice; Nitriles; Oxazoles; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Proteome; Pyrethrins; Substrate Specificity; Tandem Mass Spectrometry; Transcription Factors; Vanadates | 2008 |
Src activation and translocation from focal adhesions to membrane ruffles contribute to formation of new adhesion sites.
Topics: Animals; Astrocytoma; Cell Adhesion; Cell Line, Tumor; Cell Shape; Cell Surface Extensions; Enzyme Activation; Enzyme Inhibitors; Focal Adhesion Kinase 1; Focal Adhesions; Humans; Isoenzymes; Recombinant Fusion Proteins; src-Family Kinases; Vanadates; Vinculin | 2009 |
Nicotine activates and up-regulates nicotinic acetylcholine receptors in bronchial epithelial cells.
Topics: Acetylcholine; Aconitine; Age Factors; alpha7 Nicotinic Acetylcholine Receptor; Animals; Autocrine Communication; Bronchi; Cells, Cultured; Dihydro-beta-Erythroidine; Dose-Response Relationship, Drug; Genistein; Gestational Age; Lung; Macaca mulatta; Mecamylamine; Membrane Potentials; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Phosphorylation; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Receptors, Nicotinic; Up-Regulation; Vanadates | 2009 |
Visualization of Src activity at different compartments of the plasma membrane by FRET imaging.
Topics: Actins; Biosensing Techniques; Cell Membrane; Cells, Cultured; Cytoskeleton; Epidermal Growth Factor; Fluorescence Resonance Energy Transfer; HeLa Cells; Humans; Microtubules; Platelet-Derived Growth Factor; Protein Transport; src-Family Kinases; Vanadates | 2009 |
Identification of protein tyrosine phosphatases and dual-specificity phosphatases in mammalian spermatozoa and their role in sperm motility and protein tyrosine phosphorylation.
Topics: Animals; Blotting, Western; Culture Media; Dogs; Dual-Specificity Phosphatases; Horses; Male; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Sperm Capacitation; Sperm Motility; Spermatozoa; Swine; Vanadates | 2009 |
Continual signaling is responsible for constitutive ERK phosphorylation in B-1a cells.
Topics: Animals; B-Lymphocytes; B7-2 Antigen; CD5 Antigens; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Intracellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred BALB C; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phospholipase C gamma; Phosphoric Monoester Hydrolases; Phosphorylation; Protein-Tyrosine Kinases; Signal Transduction; src-Family Kinases; Syk Kinase; Vanadates | 2009 |
Heat shock protein 70-mediated sensitization of cells to apoptosis by Carboxyl-Terminal Modulator Protein.
Topics: Adaptor Proteins, Signal Transducing; Apoptosis; Apoptotic Protease-Activating Factor 1; Cell Line; Enzyme Inhibitors; Gene Expression Regulation; HeLa Cells; HSP70 Heat-Shock Proteins; Humans; Membrane Proteins; Mitochondria; Phosphorylation; Staurosporine; Thiolester Hydrolases; Vanadates | 2009 |
A protein tyrosine phosphatase inhibitor, pervanadate, inhibits angiotensin II-Induced beta-arrestin cleavage.
Topics: Angiotensin II; Animals; Arrestins; beta-Arrestin 1; beta-Arrestins; Blotting, Western; Chlorocebus aethiops; COS Cells; Dose-Response Relationship, Drug; Enzyme Inhibitors; Green Fluorescent Proteins; Hydrolysis; Molybdenum; Phosphorylation; Protein Conformation; Protein Tyrosine Phosphatases; Rats; Receptor, Angiotensin, Type 1; Transfection; Tyrosine; Vanadates; Vasoconstrictor Agents | 2009 |
Analysis of signaling events by dynamic phosphoflow cytometry.
Topics: Antibodies; Calibration; Cell Survival; Flow Cytometry; Gene Expression; Humans; Kinetics; Mutation; Pharmaceutical Preparations; Phosphoproteins; Phosphorylation; Protein Kinases; Proteins; PTEN Phosphohydrolase; Signal Transduction; U937 Cells; Vanadates | 2009 |
Catalytic activity of the proteasome fine-tunes Brg1-mediated chromatin remodeling to regulate the expression of inflammatory genes.
Topics: Aclarubicin; Animals; Biocatalysis; Chromatin Assembly and Disassembly; Chromosomal Proteins, Non-Histone; DNA Helicases; Inflammation; Interleukin-6; Kinetics; Mice; Nuclear Proteins; Nucleosomes; Promoter Regions, Genetic; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Transcription Factors; Vanadates | 2009 |
Tyrosine phosphorylation by Src within the cavity of the adenine nucleotide translocase 1 regulates ADP/ATP exchange in mitochondria.
Topics: Adenine Nucleotide Translocator 1; Adenosine Diphosphate; Adenosine Triphosphate; Computer Simulation; HeLa Cells; Humans; Hydrogen Peroxide; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mitochondria; Mitochondrial ADP, ATP Translocases; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myocardium; Nucleotide Transport Proteins; Phosphorylation; Protein Conformation; Protein Kinase Inhibitors; Protein Processing, Post-Translational; Protein Stability; Protein Structure, Tertiary; Pyrimidines; Recombinant Fusion Proteins; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; src-Family Kinases; Structure-Activity Relationship; Transfection; Tyrosine; Vanadates | 2010 |
Down-regulation of protein-tyrosine phosphatases activates an immune receptor in the absence of its translocation into lipid rafts.
Topics: Animals; Antigens; Cell Line, Tumor; Enzyme Activation; Enzyme Inhibitors; Hydrogen Peroxide; Mast Cells; Membrane Microdomains; Mice; Oxidants; Oxidation-Reduction; Phosphorylation; Protein Transport; Protein Tyrosine Phosphatases; Rats; Receptors, IgE; src-Family Kinases; Vanadates | 2010 |
Tandem fluorescence imaging of dynamic S-acylation and protein turnover.
Topics: Acylation; Fluorescence; HeLa Cells; Humans; Jurkat Cells; Lipoylation; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Molecular Imaging; Palmitates; Protein Biosynthesis; T-Lymphocytes; Vanadates | 2010 |
SHP-1 inhibits β-catenin function by inducing its degradation and interfering with its association with TATA-binding protein.
Topics: Animals; beta Catenin; Cell Nucleus; Cells, Cultured; CSK Tyrosine-Protein Kinase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Mice, Inbred C57BL; Mutation; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein-Tyrosine Kinases; RNA Interference; src-Family Kinases; TATA-Box Binding Protein; Ubiquitination; Vanadates | 2011 |
PTP1B suppresses prolactin activation of Stat5 in breast cancer cells.
Topics: Breast Neoplasms; Carcinoma; Down-Regulation; Drug Synergism; Dual Specificity Phosphatase 3; Enzyme Inhibitors; Female; Humans; Phosphorylation; Prolactin; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Protein Tyrosine Phosphatase, Non-Receptor Type 6; STAT5 Transcription Factor; Tumor Cells, Cultured; Vanadates | 2010 |
The Bartonella henselae VirB/Bep system interferes with vascular endothelial growth factor (VEGF) signalling in human vascular endothelial cells.
Topics: Bacterial Proteins; Bartonella henselae; Blotting, Western; Calcium; Electrophoresis, Polyacrylamide Gel; Endothelial Cells; Humans; Immunoblotting; Mitogen-Activated Protein Kinases; Phospholipase C gamma; Phosphorylation; Polymerase Chain Reaction; Signal Transduction; Vanadates; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2011 |
β-Escin sodium inhibits inducible nitric oxide synthase expression via downregulation of the JAK/STAT pathway in A549 cells.
Topics: Active Transport, Cell Nucleus; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Enzyme Activation; Enzyme Inhibitors; Escin; Humans; Janus Kinases; JNK Mitogen-Activated Protein Kinases; Lung; Lung Neoplasms; MAP Kinase Signaling System; NF-kappa B; Nitric Oxide Synthase Type II; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; RNA Interference; RNA, Small Interfering; STAT Transcription Factors; Vanadates | 2011 |
Inhibition of JAK1/STAT3 signaling mediates compound K-induced apoptosis in human multiple myeloma U266 cells.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Caspase 3; Cell Cycle; Cell Line, Tumor; Cell Survival; Down-Regulation; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Ginsenosides; Humans; Janus Kinase 1; Multiple Myeloma; Panax; Poly(ADP-ribose) Polymerases; Protein Tyrosine Phosphatases; Signal Transduction; STAT3 Transcription Factor; Vanadates | 2011 |
TC-PTP dephosphorylates the guanine nucleotide exchange factor C3G (RapGEF1) and negatively regulates differentiation of human neuroblastoma cells.
Topics: Cell Differentiation; Cell Line, Tumor; Colforsin; Golgi Apparatus; Guanine Nucleotide-Releasing Factor 2; HEK293 Cells; Humans; Mutant Proteins; Neurites; Neuroblastoma; Phosphorylation; Phosphotyrosine; Protein Binding; Protein Structure, Tertiary; Protein Transport; Protein Tyrosine Phosphatase, Non-Receptor Type 2; src-Family Kinases; Structure-Activity Relationship; Vanadates | 2011 |
Protein-tyrosine phosphatases are involved in interferon resistance associated with insulin resistance in HepG2 cells and obese mice.
Topics: Animals; Antiviral Agents; Enzyme Inhibitors; Gene Knockdown Techniques; Gene Silencing; Hep G2 Cells; Hepatitis C, Chronic; Humans; Hypoglycemic Agents; Insulin Receptor Substrate Proteins; Insulin Resistance; Interferon-alpha; Male; Metformin; Mice; Mice, Obese; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Ribavirin; STAT1 Transcription Factor; Tumor Necrosis Factor-alpha; Vanadates | 2012 |
PTPIP51 in protein interactions: regulation and in situ interacting partners.
Topics: 14-3-3 Proteins; Apoptosis; Cell Line; Cyclic AMP-Dependent Protein Kinases; Diacylglycerol Kinase; Humans; Keratinocytes; Mitochondrial Proteins; Phosphorylation; Protein Binding; Protein Interaction Mapping; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-raf; Pyrimidines; src-Family Kinases; Vanadates | 2012 |
Spontaneous and pronase-induced HER2 truncation increases the trastuzumab binding capacity of breast cancer tissues and cell lines.
Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; DNA, Neoplasm; Enzyme Inhibitors; Female; Flow Cytometry; Humans; In Situ Hybridization, Fluorescence; Pronase; Protein Binding; Receptor, ErbB-2; Trastuzumab; Vanadates | 2013 |
Regulation of muscle acetylcholine receptor turnover by β subunit tyrosine phosphorylation.
Topics: Agrin; Animals; Cell Membrane; Cells, Cultured; Half-Life; Mice; Mice, Transgenic; Muscle Fibers, Skeletal; Muscle Proteins; Muscle, Skeletal; Mutagenesis, Site-Directed; Neuromuscular Junction; Phosphorylation; Phosphotyrosine; Protein Interaction Mapping; Protein Processing, Post-Translational; Protein Stability; Protein Subunits; Receptors, Nicotinic; Recombinant Fusion Proteins; Synapses; Vanadates | 2013 |
Control of ALK (wild type and mutated forms) phosphorylation: specific role of the phosphatase PTP1B.
Topics: Anaplastic Lymphoma Kinase; Animals; Dimerization; Endoplasmic Reticulum; Humans; Mice; NIH 3T3 Cells; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor Protein-Tyrosine Kinases; src-Family Kinases; Transfection; Tyrosine; Vanadates | 2013 |
Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol.
Topics: Adaptor Proteins, Signal Transducing; Amino Acid Sequence; Amino Acids; Animals; Cell Membrane; Chlorocebus aethiops; COS Cells; Diglycerides; Epidermal Growth Factor; GTPase-Activating Proteins; HeLa Cells; Humans; Models, Molecular; Molecular Sequence Data; Neoplasm Proteins; Oncogene Proteins; Proline-Rich Protein Domains; Protein Binding; Protein Transport; rac GTP-Binding Proteins; src Homology Domains; Structure-Activity Relationship; Vanadates | 2013 |
B7-H5 costimulates human T cells via CD28H.
Topics: Amino Acid Sequence; Animals; B7 Antigens; CD28 Antigens; Coculture Techniques; Epitopes; Fluoresceins; Gene Expression Regulation; Genome, Human; HEK293 Cells; Humans; Ligands; Lymphocyte Activation; Membrane Proteins; Mice; Molecular Sequence Data; Phosphorylation; Phosphotyrosine; Protein Binding; Signal Transduction; Succinimides; T-Lymphocytes; Vanadates | 2013 |
Src Dependent Pancreatic Acinar Injury Can Be Initiated Independent of an Increase in Cytosolic Calcium.
Topics: Acinar Cells; Animals; Calcium; Cytosol; Dasatinib; Enzyme Activation; Fluorescent Antibody Technique; Mice; Mice, Inbred ICR; src-Family Kinases; Vanadates | 2013 |
Ex vivo chemical cytometric analysis of protein tyrosine phosphatase activity in single human airway epithelial cells.
Topics: Bronchi; Cell Line; Electrophoresis, Capillary; Enzyme Inhibitors; Epithelial Cells; Half-Life; Humans; Hydrolysis; Microinjections; Naphthoquinones; Phosphoproteins; Primary Cell Culture; Protein Tyrosine Phosphatases; Single-Cell Analysis; Vanadates | 2014 |
A systems toxicology approach identifies Lyn as a key signaling phosphoprotein modulated by mercury in a B lymphocyte cell model.
Topics: Animals; Autoimmune Diseases; B-Lymphocytes; Biomarkers; Cell Line; Chromatography, High Pressure Liquid; Mercury; Mercury Poisoning; Mice; Osmolar Concentration; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Protein Tyrosine Phosphatases; Receptors, Antigen, B-Cell; Signal Transduction; src-Family Kinases; Tandem Mass Spectrometry; Tyrosine; Vanadates | 2014 |
Redox-regulated pathway of tyrosine phosphorylation underlies NF-κB induction by an atypical pathway independent of the 26S proteasome.
Topics: Aclarubicin; Animals; Cell Line; Enzyme Activation; Humans; I-kappa B Kinase; Mice; Mitogen-Activated Protein Kinase Kinases; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Phosphorylation; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Protein Kinase Inhibitors; Protein Tyrosine Phosphatases; Signal Transduction; src-Family Kinases; Tyrosine; Vanadates | 2015 |
Evaluation of Kinase Activity Profiling Using Chemical Proteomics.
Topics: Blotting, Western; Cell Line, Tumor; Chromatography, Liquid; Enzyme Activation; Enzyme Inhibitors; Enzymes, Immobilized; Humans; Mass Spectrometry; Protein Kinases; Proteomics; Vanadates | 2015 |
Thermal proteome profiling monitors ligand interactions with cellular membrane proteins.
Topics: ATP Binding Cassette Transporter, Subfamily B; Caco-2 Cells; Hot Temperature; Humans; Jurkat Cells; K562 Cells; Ligands; Membrane Proteins; Protein Binding; Protein Stability; Proteome; Proteomics; Receptors, Antigen, T-Cell; Small Molecule Libraries; Sodium-Potassium-Exchanging ATPase; Tandem Mass Spectrometry; Vanadates | 2015 |
Pervanadate induces Mammalian Ste20 Kinase 3 (MST3) tyrosine phosphorylation but not activation.
Topics: Amino Acid Sequence; Animals; Dogs; Enzyme Assays; Enzyme Inhibitors; Gene Expression Regulation; HEK293 Cells; Humans; Kinetics; Madin Darby Canine Kidney Cells; Osmolar Concentration; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases; Signal Transduction; Tyrosine; Vanadates | 2016 |
Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer.
Topics: A549 Cells; Animals; Antineoplastic Agents; Apoptosis; Capsaicin; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme Activation; Humans; Janus Kinase 1; Ki-67 Antigen; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Phosphorylation; Prostatic Neoplasms; Protein Tyrosine Phosphatases; Receptor-Like Protein Tyrosine Phosphatases, Class 4; RNA Interference; RNA, Small Interfering; STAT3 Transcription Factor; Vanadates; Xenograft Model Antitumor Assays | 2017 |
Optimized logic rules reveal interferon-γ-induced modes regulated by histone deacetylases and protein tyrosine phosphatases.
Topics: Animals; Cell Line, Tumor; Choriocarcinoma; Computer Simulation; Epigenetic Repression; Female; Gene Expression Profiling; Gene Expression Regulation; Histone Deacetylases; Humans; Interferon-gamma; Mice; Placentation; Pregnancy; Protein Tyrosine Phosphatases; Response Elements; Valproic Acid; Vanadates | 2017 |
Crk adaptor proteins regulate CD3ζ chain phosphorylation and TCR/CD3 down-modulation in activated T cells.
Topics: Animals; Antibodies; CD3 Complex; Chlorocebus aethiops; COS Cells; Cross-Linking Reagents; Down-Regulation; Humans; Jurkat Cells; Lymphocyte Activation; Mice; Molecular Weight; Phosphorylation; Phosphotyrosine; Protein Binding; Proto-Oncogene Proteins c-crk; Receptors, Antigen, T-Cell; src Homology Domains; T-Lymphocytes; Vanadates; ZAP-70 Protein-Tyrosine Kinase | 2017 |
Tyrosine Phosphorylation of Carcinoembryonic Antigen-related Cell Adhesion Molecule 20 and Its Functional Role.
Topics: Actin Cytoskeleton; Cell Adhesion Molecules; CSK Tyrosine-Protein Kinase; HEK293 Cells; Humans; Phagocytosis; Phosphatidylinositol 3-Kinases; Phospholipase C gamma; Phosphorylation; src-Family Kinases; Syk Kinase; Vanadates | 2013 |
Mercury alters endogenous phosphorylation profiles of SYK in murine B cells.
Topics: Animals; Antibodies, Anti-Idiotypic; B-Lymphocytes; Cell Line, Tumor; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Mercury; Mice; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Receptors, Antigen, B-Cell; Signal Transduction; Syk Kinase; Tandem Mass Spectrometry; Tyrosine; Vanadates | 2017 |
Psychological Features and Their Relationship to Movement-Based Subgroups in People Living With Low Back Pain.
Topics: Adaptation, Psychological; Adolescent; Adult; Avoidance Learning; Catastrophization; Cross-Sectional Studies; Depression; Disability Evaluation; Fear; Female; Humans; Low Back Pain; Male; Movement; Pain Measurement; Prognosis; Psychiatric Status Rating Scales; Risk Factors; Self Efficacy; Stress, Psychological; Surveys and Questionnaires; Vanadates; Young Adult | 2018 |
Tandem Mass Tag Approach Utilizing Pervanadate BOOST Channels Delivers Deeper Quantitative Characterization of the Tyrosine Phosphoproteome.
Topics: Humans; Ions; Jurkat Cells; Phosphopeptides; Phosphoproteins; Phosphotyrosine; Proteome; Proteomics; Tandem Mass Spectrometry; Vanadates | 2020 |
PP2A
Topics: Amino Acid Sequence; Animals; Antibodies; Antibodies, Monoclonal; Antibody Specificity; Cross Reactions; Epidermal Growth Factor; HEK293 Cells; Humans; Leucine; Lymphocyte Activation; Methylation; Mice; Mice, Inbred C57BL; NIH 3T3 Cells; Peptides; Phosphorylation; Phosphotyrosine; Protein Phosphatase 2; Protein Processing, Post-Translational; src-Family Kinases; T-Lymphocytes; Vanadates | 2020 |
Multiple Signaling Roles of CD3ε and Its Application in CAR-T Cell Therapy.
Topics: Amino Acid Motifs; Animals; CD3 Complex; Cell Line; CSK Tyrosine-Protein Kinase; Cytokines; Humans; Immunotherapy, Adoptive; Lymphocyte Activation; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Mice; Mice, Inbred NOD; Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptors, Antigen, T-Cell; Receptors, Chimeric Antigen; Signal Transduction; Survival Analysis; Vanadates | 2020 |