Page last updated: 2024-08-22

vanadates and bis(maltolato)oxovanadium(iv)

vanadates has been researched along with bis(maltolato)oxovanadium(iv) in 72 studies

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's16 (22.22)18.2507
2000's40 (55.56)29.6817
2010's13 (18.06)24.3611
2020's3 (4.17)2.80

Authors

AuthorsStudies
Hoveyda, HR; McNeill, JH; Orvig, C; Yuen, VG1
Chen, X; Diamond, J; Hei, YJ; McNeill, JH; Pelech, SL1
McNeill, JH; Orvig, C; Yuen, VG2
Grosmaire, L; Ledbetter, JA; Myrdal, S; Schieven, GL; Wahl, AF1
Bhanot, S; Bryer-Ash, M; Cheung, A; McNeill, JH1
Grosmaire, LS; Ledbetter, JA; Linsley, PS; Myrdal, S; Schieven, GL; Sherbina, NV1
Bailey, TS; Brown, TJ; Marquardt, H; Mittler, RS; Nadler, SG; Shuford, WW; Wang, WC1
Arsenault, L; Burt, HM; Cindric, S; Cruz, TF; Degan, D; Hunter, WL; Jackson, JK; Min, W; Von Hoff, DD1
Esselstyn, JM; Kavanagh, TJ; Krejsa, CM; Ledbetter, JA; Nadler, SG; Schieven, GL1
Battell, ML; McNeill, JH; Yao, J1
Battell, M; Lyster, DM; McNeill, JH; Orvig, C; Ruth, TJ; Setyawati, IA; Sun, Y; Thompson, KH; Vo, C; Yuen, VG; Zeisler, S1
Dabroś, W; Dziga, D; Gryboś, R; Kordowiak, AM2
Amin, SS; Brichard, SM; Buchet, JP; Crans, DC; Ongemba, LN; Reul, BA1
Battell, ML; Li, WM; McNeill, JH; Vera, E; Yuen, VG1
Bhanot, S; Girn, J; McNeill, JH; Poucheret, P1
Dawson, G; Kilkus, J; Schieven, GL1
Li, SH; McNeill, JH1
Crans, DC; Goldfine, AB; Khan, HR; Kostyniak, PJ; McNeill, JH; Willsky, GR; Yang, LQ1
McNeill, JH; Wang, J; Yuen, VG1
Brownsey, RW; Cam, MC; McNeill, JH; Rodrigues, B1
Bhanot, S; McNeill, JH; Mohammad, A1
Bhanot, S; Marzban, L; McNeill, JH1
Goyal, RK; Mehta, AA; Shinde, UA1
McNeill, JH; Mohammad, A; Wang, J1
Battell, M; McNeill, JH; Orvig, C; Thompson, KH; Tsukada, Y; Xu, Z1
McNeill, JH; Mohammad, A; Sharma, V1
Brownsey, RW; Marzban, L; McNeill, JH; Rahimian, R1
Dabroś, W; Dziga, D; Kordowiak, AM2
Davis, MG; Diven, C; Eby-Wilkens, E; Evdokimov, A; Genbauffe, F; Greis, KD; Howard, BW; Maier, M; Peters, KG; Pokross, M; Rastogi, V; Soper, S1
Battell, ML; Bhanot, S; McNeill, JH; Orvig, C; Yuen, VG1
Carr, AN; Davis, MG; Dufresne, TE; Eby-Wilkens, E; Howard, BW; Peters, KG; Towne, BA1
Duncker, DJ; Gho, BC; Gho, CC; Kazim, S; Liem, DA; Manintveld, OC; Verdouw, PD1
Chiles, J; McNeill, JH; Orvig, C; Thompson, KH; Tse, J; Yuen, VG1
Lv, WL; Zhang, H; Zhang, Q; Zhang, X; Zhong, XY1
Crans, DC; Wang, K; Yang, XD; Yang, XG; Yuan, L1
Barve, V; Bhonde, R; Padhye, S; Shukla, R1
Davis, MG; Downs, TR; Gerwe, GS; Kasibhatla, B; Lange, JS; Peters, KG; Winter, CL1
Aebischer, N; Hanson, GR; Lam, E; Liboiron, BD; Orvig, C; Thompson, KH1
McNeill, JH; Orvig, C; Patrick, BO; Pink, M; Saatchi, K; Thompson, KH; Yuen, VG1
Brady, MJ; Makinen, MW; Mustafi, D; Ou, H; Yan, L1
Shah, DI; Singh, M2
Truett, GE1
Mehdi, MZ; Pandey, SK; Srivastava, AK; Vardatsikos, G1
Bose, S; Farah, MA; Jung, HC; Kim, Y; Lee, JH1
Balakumar, P; Jindal, S; Singh, M1
Arsenault, L; Banquerigo, ML; Boyle, DL; Brahn, E; Cheng, TP; Cruz, TF; Firestein, GS; Oliver, SJ1
Chen, GH; Lu, WL; Zhang, Q; Zhang, SQ; Zhong, XY1
Baruah, B; Crans, DC; Ding, W; Li, M; Wang, R1
Bordbar, AK; Creagh, AL; Haynes, CA; Mohammadi, F; Orvig, C1
LeBel, C; Lichter, J; McNeill, JH; Orvig, C; Scaife, MC; Thompson, KH1
Mehdi, MZ; Srivastava, AK; Vardatsikos, G1
Aureliano, M; Carvalho, E; Crans, DC; Eriksson, JW; Pereira, MJ1
Baran, EJ; Parajón-Costa, BS1
Iglesias-González, T; Llopis-González, J; Montes-Bayón, M; Sánchez-González, C; Sanz-Medel, A1
Bermudez-Peña, C; Guerrero-Romero, F; Llopis, J; Montes-Bayon, M; Sanchez-Gonzalez, C; Sanz-Medel, A; Trenzado, CE1
Bíró, L; Buglyó, P; Garribba, E; Micera, G; Sanna, D1
Adamczyk, A; Ciurkot, K; Dąbroś, W; Kordowiak, AM1
Chen, JX; Liao, DF; Tuo, Q; Zeng, H1
Al-Qatati, A; Barisas, BG; Chatterjee, PB; Crans, DC; Roess, DA; Schoeberl, S; Winter, PW; Wolf-Ringwall, AL1
Davies, JT; Goenaga-Infante, H; Gómez Ariza, JL; González, M; Marshall, D; Nischwitz, V1
Aranda, P; Gómez-Aracena, J; Llopis, J; López-Chaves, C; López-Jurado, M; Montes-Bayón, M; Sánchez-González, C; Sanz-Medel, A; Trenzado, CE1
Algieri, F; Gálvez, J; Gómez-Aracena, J; Llopis, J; López-Chaves, C; Montes-Bayon, M; Rivas-García, L; Rodríguez-Nogales, A; Sánchez-González, C; Sanz-Medel, A; Vera-Ramírez, L1
Cichon, AC; Clark, O; Di Florio, A; Jugov, R; Maeshima, R; Park, I; Rustin, S; Stoker, AW1
Cong, XQ; Li, Y; Liu, Y; Piao, MH; Xie, L1
Galvez, J; Llopis, J; Lopez-Chaves, C; Montes-Bayon, M; Moreno, L; Nebot, E; Pietschmann, P; Rodriguez-Nogales, A; Sanchez-Gonzalez, C; Sanz-Medel, A1
Aranda, P; Arredondo, M; Diéguez, AR; Llopis, J; Lopez, P; Montes-Bayon, M; Quiles, JL; Rivas-García, L; Sánchez-González, C; Varela-López, A1
de Kimpe, S; de Vries, MR; Gutiérrez, S; Johansson, ME; Meijerink, H; Parma, L; Peters, HAB; Quax, PHA1
Aranda, P; Llopis, J; López-Varela, A; Montes-Bayón, M; Quiles, JL; Rivas-García, L; Sánchez-González, C1

Reviews

2 review(s) available for vanadates and bis(maltolato)oxovanadium(iv)

ArticleYear
Vanadium treatment of type 2 diabetes: a view to the future.
    Journal of inorganic biochemistry, 2009, Volume: 103, Issue:4

    Topics: Clinical Trials as Topic; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Organometallic Compounds; Pyrones; Vanadates

2009
Bis(maltolato)-oxovanadium (IV)-induced phosphorylation of PKB, GSK-3 and FOXO1 contributes to its glucoregulatory responses (review).
    International journal of molecular medicine, 2009, Volume: 24, Issue:3

    Topics: Animals; Forkhead Transcription Factors; Glucose; Glycogen Synthase Kinase 3; Humans; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrones; Vanadates

2009

Trials

1 trial(s) available for vanadates and bis(maltolato)oxovanadium(iv)

ArticleYear
Effect of vanadium(IV) compounds in the treatment of diabetes: in vivo and in vitro studies with vanadyl sulfate and bis(maltolato)oxovandium(IV).
    Journal of inorganic biochemistry, 2001, Volume: 85, Issue:1

    Topics: Animals; Apoproteins; Biological Availability; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Electron Spin Resonance Spectroscopy; Fasting; Humans; Hypoglycemic Agents; Immunoglobulin G; Male; Pyrones; Rats; Rats, Wistar; Serum Albumin; Streptozocin; Transferrin; Treatment Outcome; Vanadates; Vanadium; Vanadium Compounds

2001

Other Studies

69 other study(ies) available for vanadates and bis(maltolato)oxovanadium(iv)

ArticleYear
Bis(maltolato)oxovanadium(IV) is a potent insulin mimic.
    Journal of medicinal chemistry, 1992, Apr-17, Volume: 35, Issue:8

    Topics: Animals; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Organometallic Compounds; Pyrones; Rats; Rats, Inbred Strains; Vanadates

1992
Skeletal muscle mitogen-activated protein kinases and ribosomal S6 kinases. Suppression in chronic diabetic rats and reversal by vanadium.
    Diabetes, 1995, Volume: 44, Issue:10

    Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Chromatography, Ion Exchange; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Insulin Resistance; Kinetics; Muscle, Skeletal; Protein Serine-Threonine Kinases; Pyrones; Rats; Rats, Wistar; Reference Values; Ribosomal Protein S6 Kinases; Ribosomes; Time Factors; Vanadates; Vanadium; Vanadium Compounds

1995
Comparison of the glucose-lowering properties of vanadyl sulfate and bis(maltolato)oxovanadium(IV) following acute and chronic administration.
    Canadian journal of physiology and pharmacology, 1995, Volume: 73, Issue:1

    Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Hypoglycemic Agents; Injections, Intraperitoneal; Injections, Intravenous; Male; Pyrones; Rats; Rats, Wistar; Time Factors; Vanadates; Vanadium Compounds

1995
Lineage-specific induction of B cell apoptosis and altered signal transduction by the phosphotyrosine phosphatase inhibitor bis(maltolato)oxovanadium(IV).
    The Journal of biological chemistry, 1995, Sep-01, Volume: 270, Issue:35

    Topics: Animals; Apoptosis; B-Lymphocytes; Calcium; Cell Line; Cytoplasm; Dose-Response Relationship, Drug; Humans; Hypoglycemic Agents; Immunoglobulin M; Kinetics; Leukemia, Promyelocytic, Acute; Leukemia, T-Cell; Lymphocyte Activation; Lymphoma, B-Cell; Mice; Phospholipases; Phytohemagglutinins; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Pyrones; Receptors, Antigen, B-Cell; Receptors, Antigen, T-Cell; Receptors, Interleukin-2; Signal Transduction; Tumor Cells, Cultured; TYK2 Kinase; Vanadates

1995
Bis(maltolato)oxovanadium(IV) attenuates hyperinsulinemia and hypertension in spontaneously hypertensive rats.
    Diabetes, 1994, Volume: 43, Issue:7

    Topics: Animals; Blood Glucose; Blood Pressure; Glucose Clamp Technique; Hyperinsulinism; Hypertension; Hypoglycemic Agents; Insulin; Male; Pyrones; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vanadates

1994
Intracellular CD22 rapidly moves to the cell surface in a tyrosine kinase-dependent manner following antigen receptor stimulation.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Nov-15, Volume: 157, Issue:10

    Topics: Antigens, CD; Antigens, Differentiation, B-Lymphocyte; Antigens, Surface; Biological Transport; Burkitt Lymphoma; Cell Adhesion Molecules; Cytoplasm; Humans; Immunization; Lectins; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pyrones; Receptors, Antigen; Sialic Acid Binding Ig-like Lectin 2; Tumor Cells, Cultured; Vanadates

1996
Characterization of a CD43/leukosialin-mediated pathway for inducing apoptosis in human T-lymphoblastoid cells.
    The Journal of biological chemistry, 1996, Nov-01, Volume: 271, Issue:44

    Topics: Antibodies, Monoclonal; Antigens, CD; Apoptosis; Base Sequence; Benzoquinones; Binding Sites; Carbohydrate Conformation; Carbohydrate Sequence; Cell Nucleus; Chromatography, Affinity; Enzyme Inhibitors; Epitopes; Flow Cytometry; Glycopeptides; Humans; Jurkat Cells; Lactams, Macrocyclic; Leukosialin; Lymphocyte Activation; Microscopy, Confocal; Molecular Sequence Data; NF-kappa B; Oligonucleotide Probes; Oligosaccharides; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pyrones; Quinones; Rifabutin; Sialoglycoproteins; T-Lymphocytes; Transcription Factors; Vanadates

1996
Effects of bis(maltolato)oxovanadium(IV) are distinct from food restriction in STZ-diabetic rats.
    The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 1

    Topics: Animals; Blood Glucose; Blood Urea Nitrogen; Cholesterol; Diabetes Mellitus, Experimental; Food Deprivation; Hypoglycemic Agents; Insulin; Insulin Resistance; Male; Pyrones; Rats; Rats, Wistar; Triglycerides; Vanadates

1997
A polymer-based drug delivery system for the antineoplastic agent bis(maltolato)oxovanadium in mice.
    British journal of cancer, 1997, Volume: 75, Issue:7

    Topics: Animals; Antineoplastic Agents; Delayed-Action Preparations; Female; Humans; Male; Mice; Mice, Inbred C3H; Mice, Inbred DBA; Microscopy, Electron, Scanning; Polyesters; Pyrones; Solubility; Tumor Cells, Cultured; Vanadates

1997
Role of oxidative stress in the action of vanadium phosphotyrosine phosphatase inhibitors. Redox independent activation of NF-kappaB.
    The Journal of biological chemistry, 1997, Apr-25, Volume: 272, Issue:17

    Topics: Antioxidants; B-Lymphocytes; Cell Line; DNA-Binding Proteins; Enzyme Activation; Enzyme Inhibitors; Humans; I-kappa B Proteins; Leukocyte Common Antigens; Lymphocytes; NF-KappaB Inhibitor alpha; Organometallic Compounds; Oxidation-Reduction; Oxidative Stress; Phenanthrolines; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Pyrones; Signal Transduction; T-Lymphocytes; Vanadates

1997
Acute and chronic response to vanadium following two methods of streptozotocin-diabetes induction.
    Canadian journal of physiology and pharmacology, 1997, Volume: 75, Issue:2

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fatty Acids, Nonesterified; Glucose Tolerance Test; Hypoglycemic Agents; Insulin; Pyrones; Rats; Rats, Sprague-Dawley; Rats, Wistar; Streptozocin; Triglycerides; Vanadates; Vanadium Compounds

1997
Kinetic analysis and comparison of uptake, distribution, and excretion of 48V-labeled compounds in rats.
    Journal of applied physiology (Bethesda, Md. : 1985), 1998, Volume: 84, Issue:2

    Topics: Animals; Computer Simulation; Hypoglycemic Agents; Male; Models, Biological; Pyrones; Rats; Rats, Wistar; Tissue Distribution; Vanadates; Vanadium Compounds

1998
Influence of bis(maltolato)oxovanadium(IV) on activity of galactosyltransferase (GalT) and morphology of rat liver Golgi apparatus in control and streptozotocin diabetes.
    Polish journal of pathology : official journal of the Polish Society of Pathologists, 1998, Volume: 49, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Female; Galactosyltransferases; Golgi Apparatus; Hypoglycemic Agents; Liver; Microscopy, Electron; Pyrones; Rats; Rats, Wistar; Streptozocin; Vanadates

1998
Effects of vanadium complexes with organic ligands on glucose metabolism: a comparison study in diabetic rats.
    British journal of pharmacology, 1999, Volume: 126, Issue:2

    Topics: Administration, Oral; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Disinfectants; Glucokinase; Glucose; Hydroxybutyrates; Hypoglycemic Agents; Injections, Intraperitoneal; Insulin; Islets of Langerhans; Ligands; Liver; Liver Glycogen; Male; Muscles; Organometallic Compounds; Pentanones; Phosphoenolpyruvate Carboxykinase (GTP); Pyrones; Pyruvate Kinase; Rats; Rats, Wistar; RNA, Messenger; Time Factors; Vanadates; Vanadium Compounds

1999
Acute and chronic oral administration of bis(maltolato)oxovanadium(IV) in Zucker diabetic fatty (ZDF) rats.
    Diabetes research and clinical practice, 1999, Volume: 43, Issue:1

    Topics: Administration, Oral; Animals; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Hypoglycemic Agents; Insulin; Male; Obesity; Pyrones; Rats; Rats, Zucker; Time Factors; Triglycerides; Vanadates

1999
Effects of bis(maltolato) oxovanadium (IV) on protein serine kinases in skeletal muscle of streptozotocin-diabetic rats.
    Molecular and cellular biochemistry, 1999, Volume: 202, Issue:1-2

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Insulin; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Protein Serine-Threonine Kinases; Pyrones; Rats; Rats, Wistar; Vanadates

1999
Selective phosphotyrosine phosphatase inhibition and increased ceramide formation is associated with B-cell death by apoptosis.
    FEBS letters, 2000, Aug-04, Volume: 478, Issue:3

    Topics: Apoptosis; B-Lymphocytes; Cell Line; Ceramides; Humans; In Situ Nick-End Labeling; Jurkat Cells; Organ Specificity; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Pyrones; Sphingomyelins; Sphingosine; T-Lymphocytes; Vanadates

2000
Biochemical and morphological alterations in rat liver Golgi complexes after treatment with bis(maltolato)oxovanadium(IV) [BMOV] or maltol alone.
    Pathology, research and practice, 2000, Volume: 196, Issue:8

    Topics: Administration, Oral; Animals; Female; Golgi Apparatus; Liver; Pyrones; Rats; Rats, Wistar; Vanadates

2000
In vivo effects of vanadium on GLUT4 translocation in cardiac tissue of STZ-diabetic rats.
    Molecular and cellular biochemistry, 2001, Volume: 217, Issue:1-2

    Topics: Animals; Blood Glucose; Cell Membrane; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Glucose Transporter Type 4; Insulin; Male; Monosaccharide Transport Proteins; Muscle Proteins; Myocardium; Ouabain; Protein Transport; Pyrones; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Vanadates

2001
Effect of vanadium on insulin sensitivity and appetite.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:6

    Topics: Adipose Tissue; Animals; Appetite; Arcuate Nucleus of Hypothalamus; Blood Glucose; Cell Nucleus; Disease Models, Animal; Hypoglycemic Agents; Hypothalamus; Immunohistochemistry; In Situ Hybridization; Insulin; Leptin; Male; Neuropeptide Y; Obesity; Pyrones; Rats; Rats, Zucker; RNA, Messenger; Vanadates; Vanadium

2001
Lack of in vivo effect of vanadium on GLUT4 translocation in white adipose tissue of streptozotocin-diabetic rats.
    Metabolism: clinical and experimental, 2001, Volume: 50, Issue:6

    Topics: Adipose Tissue; Animals; Blood Glucose; Body Weight; Cell Membrane; Diabetes Mellitus, Experimental; Glucose Tolerance Test; Glucose Transporter Type 4; Hypoglycemic Agents; Insulin; Male; Monosaccharide Transport Proteins; Muscle Proteins; Pyrones; Rats; Rats, Wistar; Time Factors; Vanadates; Vanadium

2001
In vivo effects of vanadium in diabetic rats are independent of changes in PI-3 kinase activity in skeletal muscle.
    Molecular and cellular biochemistry, 2001, Volume: 223, Issue:1-2

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Hypoglycemic Agents; Insulin; Male; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Pyrones; Rats; Rats, Wistar; Rats, Zucker; Signal Transduction; Vanadates

2001
In vivo effects of insulin and bis(maltolato)oxovanadium (IV) on PKB activity in the skeletal muscle and liver of diabetic rats.
    Molecular and cellular biochemistry, 2001, Volume: 223, Issue:1-2

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Insulin; Liver; Male; Muscle, Skeletal; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Pyrones; Random Allocation; Rats; Rats, Wistar; Rats, Zucker; Tissue Extracts; Vanadates

2001
Effect of chronic treatment with Bis(maltolato)oxovanadium (IV) in rat model of non-insulin-dependent-diabetes.
    Indian journal of experimental biology, 2001, Volume: 39, Issue:9

    Topics: Animals; Blood Glucose; Body Weight; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Glucose Tolerance Test; Hypercholesterolemia; Hypoglycemic Agents; Insulin; Male; Pyrones; Rats; Rats, Wistar; Vanadates

2001
Bis(maltolato)oxovanadium(IV) inhibits the activity of PTP1B in Zucker rat skeletal muscle in vivo.
    Molecular and cellular biochemistry, 2002, Volume: 229, Issue:1-2

    Topics: Animals; Blood Glucose; Body Weight; Enzyme Inhibitors; Insulin; Male; Muscle, Skeletal; Obesity; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Pyrones; Rats; Rats, Zucker; Vanadates

2002
Influence of chelation and oxidation state on vanadium bioavailability, and their effects on tissue concentrations of zinc, copper, and iron.
    Biological trace element research, 2002, Volume: 86, Issue:1

    Topics: Animals; Biological Availability; Bone and Bones; Caco-2 Cells; Copper; Humans; Iron; Kidney; Male; Oxidation-Reduction; Pyrones; Rats; Rats, Wistar; Vanadates; Vanadium; Vanadium Compounds; Zinc

2002
Vanadium increases GLUT4 in diabetic rat skeletal muscle.
    Molecular and cellular biochemistry, 2002, Volume: 233, Issue:1-2

    Topics: Animals; Diabetes Mellitus, Experimental; DNA Primers; Glucose Transporter Type 4; Hypoglycemic Agents; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Pyrones; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Up-Regulation; Vanadates

2002
Mechanisms by which bis(maltolato)oxovanadium(IV) normalizes phosphoenolpyruvate carboxykinase and glucose-6-phosphatase expression in streptozotocin-diabetic rats in vivo.
    Endocrinology, 2002, Volume: 143, Issue:12

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Gene Expression; Glucose-6-Phosphatase; Hypoglycemic Agents; Insulin; Kidney; Liver; Male; Phlorhizin; Phosphoenolpyruvate Carboxykinase (GTP); Pyrones; Rats; Rats, Wistar; RNA, Messenger; Vanadates

2002
The influence of BMOV [bis(maltolato)oxovanadium(IV)] on biochemical and morphological alterations characteristic for streptozotocin-diabetic rat liver Golgi complexes.
    Polish journal of pathology : official journal of the Polish Society of Pathologists, 2002, Volume: 53, Issue:4

    Topics: Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Female; Galactosyltransferases; Golgi Apparatus; Liver; Microscopy, Electron; Pyrones; Rats; Rats, Wistar; Vanadates

2002
Mechanism of insulin sensitization by BMOV (bis maltolato oxo vanadium); unliganded vanadium (VO4) as the active component.
    Journal of inorganic biochemistry, 2003, Aug-01, Volume: 96, Issue:2-3

    Topics: Animals; Binding, Competitive; Crystallography, X-Ray; Drug Synergism; Humans; Hypoglycemic Agents; Insulin; Molecular Structure; Myocardium; Nuclear Magnetic Resonance, Biomolecular; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Pyrones; Rats; Receptor, Insulin; Vanadates

2003
Chronic glucose-lowering effects of rosiglitazone and bis(ethylmaltolato)oxovanadium(IV) in ZDF rats.
    Canadian journal of physiology and pharmacology, 2003, Volume: 81, Issue:11

    Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Drug Administration Schedule; Drug Therapy, Combination; Insulin; Intubation, Gastrointestinal; Male; Pyrones; Rats; Rats, Zucker; Rosiglitazone; Thiazolidinediones; Vanadates

2003
Tyrosine phosphatase inhibition augments collateral blood flow in a rat model of peripheral vascular disease.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:1

    Topics: Animals; Cell Survival; Cells, Cultured; Collateral Circulation; Endothelium, Vascular; Humans; In Vitro Techniques; Male; Neovascularization, Physiologic; Phosphoric Monoester Hydrolases; Protein Tyrosine Phosphatases; Pyrones; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptor, TIE-2; Vanadates; Vascular Diseases

2004
The tyrosine phosphatase inhibitor bis(maltolato)oxovanadium attenuates myocardial reperfusion injury by opening ATP-sensitive potassium channels.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:3

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Potassium Channels; Protein Tyrosine Phosphatases; Pyrones; Rats; Rats, Wistar; Time Factors; Tyrosine; Vanadates

2004
Streptozotocin-induced alterations in rat liver Golgi complexes are ameliorated by BMOV [Bis(maltolato)oxovanadium(IV)] activity.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2004, Volume: 36, Issue:3

    Topics: Animals; Diabetes Mellitus, Experimental; Female; Galactosyltransferases; Golgi Apparatus; Hypoglycemic Agents; Liver; Microscopy, Electron; Osmolar Concentration; Phospholipids; Pyrones; Rats; Rats, Wistar; Sodium Chloride; Vanadates; Vanadium

2004
Comparison of anti-hyperglycemic effect amongst vanadium, molybdenum and other metal maltol complexes.
    Journal of inorganic biochemistry, 2004, Volume: 98, Issue:5

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Male; Molybdenum; Organometallic Compounds; Pyrones; Rats; Rats, Wistar; Vanadates; Vanadium

2004
[Hypoglycemic effects of bis(maltolato)oxovanadium administered by different routes upon diabetic rats].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2004, Jun-18, Volume: 36, Issue:3

    Topics: Administration, Oral; Alloxan; Animals; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Injections, Intraperitoneal; Injections, Intravenous; Injections, Subcutaneous; Insulin; Male; Pyrones; Rats; Rats, Wistar; Vanadates

2004
The permeability and cytotoxicity of insulin-mimetic vanadium compounds.
    Pharmaceutical research, 2004, Volume: 21, Issue:6

    Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Actins; Caco-2 Cells; Cell Membrane Permeability; Cell Survival; China; Diffusion; Electric Impedance; Formazans; Humans; Hydrogen Peroxide; Hydroxybutyrates; Hypoglycemic Agents; Microscopy, Confocal; Microscopy, Electron, Scanning; Microvilli; Pentanones; Pyrones; Reactive Oxygen Species; Spectrophotometry, Atomic; Superoxides; Tetrazolium Salts; Vanadates; Vanadium Compounds

2004
Synthesis, structural properties and insulin-enhancing potential of bis(quercetinato)oxovanadium(IV) conjugate.
    Bioorganic & medicinal chemistry letters, 2004, Oct-04, Volume: 14, Issue:19

    Topics: Animals; Hypoglycemic Agents; Magnetics; Male; Mice; Mice, Inbred BALB C; Mitogens; Pyrones; Quercetin; Vanadates

2004
A nonspecific phosphotyrosine phosphatase inhibitor, bis(maltolato)oxovanadium(IV), improves glucose tolerance and prevents diabetes in Zucker diabetic fatty rats.
    Experimental biology and medicine (Maywood, N.J.), 2005, Volume: 230, Issue:3

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glucose Tolerance Test; Hyperinsulinism; Hypoglycemic Agents; Insulin; Insulin Resistance; Obesity; Pancreas; Protein Tyrosine Phosphatases; Pyrones; Rats; Rats, Zucker; Time Factors; Vanadates

2005
New insights into the interactions of serum proteins with bis(maltolato)oxovanadium(IV): transport and biotransformation of insulin-enhancing vanadium pharmaceuticals.
    Journal of the American Chemical Society, 2005, Apr-13, Volume: 127, Issue:14

    Topics: Apoproteins; Biotransformation; Drug Synergism; Electron Spin Resonance Spectroscopy; Humans; Imidazoles; Insulin; Kinetics; Molecular Weight; Pyrones; Serum Albumin; Transferrin; Vanadates; Vanadium Compounds

2005
Coordination chemistry and insulin-enhancing behavior of vanadium complexes with maltol C6H6O3 structural isomers.
    Inorganic chemistry, 2005, Apr-18, Volume: 44, Issue:8

    Topics: Animals; Blood Glucose; Crystallography, X-Ray; Diabetes Mellitus, Experimental; Hydrogen-Ion Concentration; Hypoglycemic Agents; Insulin; Isomerism; Ligands; Pyrones; Rats; Time Factors; Vanadates; Vanadium Compounds

2005
The vanadyl (VO2+) chelate bis(acetylacetonato)oxovanadium(IV) potentiates tyrosine phosphorylation of the insulin receptor.
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry, 2005, Volume: 10, Issue:8

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Chelating Agents; Enzyme Activation; Glycogen; Glycogen Synthase; Hypoglycemic Agents; Insulin Resistance; Mice; Molecular Structure; Organometallic Compounds; Phosphorylation; Pyrones; Receptor, Insulin; Solutions; Tyrosine; Vanadates

2005
Inhibition of protein tyrosin phosphatase improves vascular endothelial dysfunction.
    Vascular pharmacology, 2006, Volume: 44, Issue:3

    Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hyperhomocysteinemia; Male; Methionine; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitrites; Potassium Channels; Protein Tyrosine Phosphatases; Pyrones; Rats; Rats, Sprague-Dawley; Streptozocin; Thiobarbituric Acid Reactive Substances; Vanadates; Vasodilation

2006
Prevention of diabetes by inhibition of tyrosine phosphatases.
    Experimental biology and medicine (Maywood, N.J.), 2006, Volume: 231, Issue:5

    Topics: Adult; Animals; Body Weight; Child; Diabetes Mellitus, Type 2; Eating; Humans; Insulin; Protein Tyrosine Phosphatases; Pyrones; Receptor, Insulin; Signal Transduction; Vanadates

2006
Effect of bis(maltolato) oxovanadium on experimental vascular endothelial dysfunction.
    Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 373, Issue:3

    Topics: Animals; Blood Pressure; Endothelins; Lipid Metabolism; Male; Microscopy, Electron, Scanning; Nitrates; Nitrites; Pyrones; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Vanadates; Vascular Diseases; Vasodilation

2006
Involvement of insulin-like growth factor type 1 receptor and protein kinase Cdelta in bis(maltolato)oxovanadium(IV)-induced phosphorylation of protein kinase B in HepG2 cells.
    Biochemistry, 2006, Sep-26, Volume: 45, Issue:38

    Topics: Animals; Cells, Cultured; CHO Cells; Cricetinae; Cricetulus; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Insulin Receptor Substrate Proteins; Oligonucleotides, Antisense; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase C-delta; Proto-Oncogene Proteins c-akt; Pyrones; Receptor, IGF Type 1; Receptor, Insulin; Signal Transduction; Tyrphostins; Vanadates

2006
Molecular mechanism of bis(maltolato)oxovanadium(IV)-induced insulin signaling in 3T3-L1 and IM9 cells: impact of dexamethasone.
    Journal of molecular endocrinology, 2007, Volume: 38, Issue:6

    Topics: 3T3-L1 Cells; Animals; Cell Line; Dexamethasone; Humans; Insulin; Mice; Protein Tyrosine Phosphatases; Pyrones; Signal Transduction; Vanadates

2007
Effect of bis (maltolato) oxovanadium (BMOV) in uric acid and sodium arsenite-induced vascular endothelial dysfunction in rats.
    International journal of cardiology, 2008, Aug-29, Volume: 128, Issue:3

    Topics: Animals; Arsenites; Endothelium, Vascular; Male; Pyrones; Rats; Rats, Wistar; Sodium Compounds; Thiobarbituric Acid Reactive Substances; Uric Acid; Vanadates; Vascular Diseases

2008
Vanadate, an inhibitor of stromelysin and collagenase expression, suppresses collagen induced arthritis.
    The Journal of rheumatology, 2007, Volume: 34, Issue:9

    Topics: Acetylcysteine; Animals; Ankle Joint; Arthritis, Experimental; Arthritis, Rheumatoid; Collagenases; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Injections, Subcutaneous; Interleukin-1; Matrix Metalloproteinase 3; Pyrones; Random Allocation; Rats; Vanadates

2007
The anti-diabetic effects and pharmacokinetic profiles of bis(maltolato)oxovanadium in non-diabetic and diabetic rats.
    The Journal of pharmacy and pharmacology, 2008, Volume: 60, Issue:1

    Topics: Administration, Oral; Alloxan; Animals; Area Under Curve; Biological Availability; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Femur; Half-Life; Hypoglycemic Agents; Injections, Intravenous; Injections, Subcutaneous; Kidney; Male; Pyrones; Rats; Rats, Sprague-Dawley; Time Factors; Vanadates

2008
Inhibition of protein tyrosine phosphatase 1B and alkaline phosphatase by bis(maltolato)oxovanadium (IV).
    Journal of inorganic biochemistry, 2008, Volume: 102, Issue:10

    Topics: Alkaline Phosphatase; Humans; Insulin; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Pyrones; Recombinant Fusion Proteins; Vanadates

2008
Calorimetric studies of the interaction between the insulin-enhancing drug candidate bis(maltolato)oxovanadium(IV) (BMOV) and human serum apo-transferrin.
    Journal of inorganic biochemistry, 2009, Volume: 103, Issue:4

    Topics: Apoproteins; Calorimetry; Drug Synergism; Humans; Hydrogen-Ion Concentration; Hypoglycemic Agents; Insulin; Kinetics; Pyrones; Transferrin; Vanadates

2009
Effects of decavanadate and insulin enhancing vanadium compounds on glucose uptake in isolated rat adipocytes.
    Journal of inorganic biochemistry, 2009, Volume: 103, Issue:12

    Topics: Adipocytes; Animals; Cells, Cultured; Glucose; Hypoglycemic Agents; Insulin; Male; Organometallic Compounds; Pyrones; Rats; Rats, Wistar; Vanadates

2009
Vibrational spectra of bis(maltolato)oxovanadium(IV): a potent insulin mimetic agent.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2011, Volume: 78, Issue:1

    Topics: Insulin; Pyrones; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Vanadates; Vibration

2011
Absorption, transport and insulin-mimetic properties of bis(maltolato)oxovanadium (IV) in streptozotocin-induced hyperglycemic rats by integrated mass spectrometric techniques.
    Analytical and bioanalytical chemistry, 2012, Volume: 402, Issue:1

    Topics: Absorption; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Humans; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Mass Spectrometry; Pyrones; Rats; Rats, Wistar; Streptozocin; Tissue Distribution; Vanadates

2012
Effect of bis(maltolato)oxovanadium (IV) (BMOV) on selenium nutritional status in diabetic streptozotocin rats.
    The British journal of nutrition, 2012, Volume: 108, Issue:5

    Topics: Animals; Diabetes Mellitus, Experimental; Male; Nutritional Status; Pyrones; Rats; Rats, Wistar; Selenium; Vanadates

2012
Biotransformation of BMOV in the presence of blood serum proteins.
    Metallomics : integrated biometal science, 2012, Volume: 4, Issue:1

    Topics: Biotransformation; Blood Proteins; Electron Spin Resonance Spectroscopy; Humans; Hypoglycemic Agents; Molecular Structure; Protein Tyrosine Phosphatases; Pyrones; Vanadates

2012
Vanadium compounds affect growth and morphology of human rhabdomyosarcoma cell line.
    Polish journal of pathology : official journal of the Polish Society of Pathologists, 2011, Volume: 62, Issue:4

    Topics: Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cell Survival; Cytoplasm; Drug Screening Assays, Antitumor; Humans; Pyrones; Rhabdomyosarcoma; Vanadates; Vanadium Compounds

2011
Inhibition of protein tyrosine phosphatase improves angiogenesis via enhancing Ang-1/Tie-2 signaling in diabetes.
    Experimental diabetes research, 2012, Volume: 2012

    Topics: Angiopoietin-1; Animals; Apoptosis; Caspase 3; Cell Line; Cells, Cultured; Diabetes Mellitus, Type 2; Endothelial Cells; Heart; Mice; Myocardium; Neovascularization, Physiologic; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Pyrones; Receptor, TIE-2; Signal Transduction; Vanadates

2012
The anti-diabetic bis(maltolato)oxovanadium(IV) decreases lipid order while increasing insulin receptor localization in membrane microdomains.
    Dalton transactions (Cambridge, England : 2003), 2012, Jun-07, Volume: 41, Issue:21

    Topics: Animals; Cell Line, Tumor; Cetrimonium; Cetrimonium Compounds; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Membrane Lipids; Membrane Microdomains; Micelles; Movement; Oxidation-Reduction; Phosphorylation; Protein Transport; Pyrones; Rats; Receptor, Insulin; Vanadates

2012
Speciation studies of vanadium in human liver (HepG2) cells after in vitro exposure to bis(maltolato)oxovanadium(IV) using HPLC online with elemental and molecular mass spectrometry.
    Metallomics : integrated biometal science, 2013, Volume: 5, Issue:12

    Topics: Chromatography, Gel; Chromatography, High Pressure Liquid; Hep G2 Cells; Humans; Hypoglycemic Agents; Liver; Protein Tyrosine Phosphatases; Pyrones; Spectrometry, Mass, Electrospray Ionization; Vanadates; Vanadium

2013
Changes in iron metabolism and oxidative status in STZ-induced diabetic rats treated with bis(maltolato) oxovanadium (IV) as an antidiabetic agent.
    TheScientificWorldJournal, 2014, Volume: 2014

    Topics: Animals; Catalase; Diabetes Mellitus, Experimental; Hypoglycemic Agents; Iron; Kidney; Liver; Male; Muscle, Skeletal; Myocardium; NAD(P)H Dehydrogenase (Quinone); Oxidation-Reduction; Pyrones; Rats; Spleen; Superoxide Dismutase; Vanadates

2014
Exposure to bis(maltolato)oxovanadium(IV) increases levels of hepcidin mRNA and impairs the homeostasis of iron but not that of manganese.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 73

    Topics: Animals; Base Sequence; DNA Primers; Environmental Exposure; Hepcidins; Homeostasis; Iron; Male; Manganese; Pyrones; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; RNA, Messenger; Vanadates

2014
Oxovanadium-based inhibitors can drive redox-sensitive cytotoxicity in neuroblastoma cells and synergise strongly with buthionine sulfoximine.
    Cancer letters, 2015, Feb-01, Volume: 357, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Cell Line, Tumor; Drug Synergism; Fibroblasts; Humans; Mice; Neuroblastoma; Oxidation-Reduction; Pyrones; Signal Transduction; Transfection; Vanadates

2015
Bis(maltolato)oxovanadium(IV) (BMOV) Attenuates Apoptosis in High Glucose-Treated Cardiac Cells and Diabetic Rat Hearts by Regulating the Unfolded Protein Responses (UPRs).
    Biological trace element research, 2016, Volume: 173, Issue:2

    Topics: Animals; Apoptosis; Cell Line; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Glucose; Male; Myocardium; Pyrones; Rats; Rats, Sprague-Dawley; Unfolded Protein Response; Vanadates

2016
Effect of vanadium on calcium homeostasis, osteopontin mRNA expression, and bone microarchitecture in diabetic rats.
    Metallomics : integrated biometal science, 2017, 03-22, Volume: 9, Issue:3

    Topics: Animals; Bone and Bones; Calcium; Diabetes Mellitus, Experimental; Homeostasis; Male; Osteopontin; Pyrones; Rats; Rats, Wistar; RNA, Messenger; Vanadates; X-Ray Microtomography

2017
In vitro study of the protective effect of manganese against vanadium-mediated nuclear and mitochondrial DNA damage.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 135

    Topics: Cell Nucleus; Cell Survival; Chlorides; DNA Damage; DNA, Mitochondrial; Hep G2 Cells; Humans; Manganese Compounds; Mitochondria; Protective Agents; Pyrones; Vanadates

2020
Bis(maltolato)oxovanadium(IV) Induces Angiogenesis via Phosphorylation of VEGFR2.
    International journal of molecular sciences, 2020, Jun-30, Volume: 21, Issue:13

    Topics: Angiogenesis Inducing Agents; Animals; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Neovascularization, Pathologic; Neovascularization, Physiologic; Phosphorylation; Protein Tyrosine Phosphatases; Pyrones; Signal Transduction; Vanadates; Vascular Endothelial Growth Factor Receptor-2

2020
Elucidating the Therapeutic Potential of Bis(Maltolato)OxoVanadium(IV): The Protective Role of Copper in Cellular Metabolism.
    International journal of molecular sciences, 2023, May-27, Volume: 24, Issue:11

    Topics: Copper; DNA, Mitochondrial; Hypoglycemic Agents; Pyrones; Trace Elements; Vanadates; Vanadium

2023