valylleucine and furan

valylleucine has been researched along with furan* in 1 studies

Other Studies

1 other study(ies) available for valylleucine and furan

Article	Year
N-heterocyclic dipeptide aldehyde calpain inhibitors. Protein and peptide letters, 2009, Volume: 16, Issue:12 A series of Val-Leu based peptidic aldehydes containing either a furan or thiophene at the N-terminus was prepared and assayed against ovine m-calpain. In general, potency is favoured by a 2-substituted (rather than 3-substituted) heterocycle, a thiophene rather than a furan, and a shorter chain length at the N-terminus. Molecular docking experiments provide some rationale for these observations. Topics: Aldehydes; Animals; Calpain; Dipeptides; Furans; Glycoproteins; Models, Molecular; Peptides, Cyclic; Protein Conformation; Sheep; Thiophenes	2009

Article

Year

N-heterocyclic dipeptide aldehyde calpain inhibitors.

Protein and peptide letters, 2009, Volume: 16, Issue:12

A series of Val-Leu based peptidic aldehydes containing either a furan or thiophene at the N-terminus was prepared and assayed against ovine m-calpain. In general, potency is favoured by a 2-substituted (rather than 3-substituted) heterocycle, a thiophene rather than a furan, and a shorter chain length at the N-terminus. Molecular docking experiments provide some rationale for these observations.

Topics: Aldehydes; Animals; Calpain; Dipeptides; Furans; Glycoproteins; Models, Molecular; Peptides, Cyclic; Protein Conformation; Sheep; Thiophenes

2009