valylleucine has been researched along with furan* in 1 studies
1 other study(ies) available for valylleucine and furan
Article | Year |
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N-heterocyclic dipeptide aldehyde calpain inhibitors.
A series of Val-Leu based peptidic aldehydes containing either a furan or thiophene at the N-terminus was prepared and assayed against ovine m-calpain. In general, potency is favoured by a 2-substituted (rather than 3-substituted) heterocycle, a thiophene rather than a furan, and a shorter chain length at the N-terminus. Molecular docking experiments provide some rationale for these observations. Topics: Aldehydes; Animals; Calpain; Dipeptides; Furans; Glycoproteins; Models, Molecular; Peptides, Cyclic; Protein Conformation; Sheep; Thiophenes | 2009 |