valsartan has been researched along with nifedipine in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 11 (32.35) | 29.6817 |
| 2010's | 19 (55.88) | 24.3611 |
| 2020's | 4 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Bharate, SS; Vishwakarma, RA | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Chan, P; Cheng, JT; Liu, IM; Tzeng, TF; Wong, KL; Yang, TL | 1 |
| Shigemasa, M; Takami, T | 1 |
| Kato, H; Munakata, M; Nagasaki, A; Nunokawa, T; Sakuma, T; Toyota, T; Yoshinaga, K | 1 |
| Mittal, BV; Pendse, S; Rennke, HG; Singh, AK | 1 |
| Saito, I; Saruta, T | 1 |
| Adachi, T; Hirakawa, N; Kamezaki, F; Kouzuma, R; Nagatomo, T; Otsuji, Y; Shibata, K; Tasaki, H; Tsutsui, M; Yamashita, K | 1 |
| Fujikawa, K; Saito, I; Saruta, T | 1 |
| Harada, N; Okajima, K; Shimozawa, N | 1 |
| Hosoya, T; Ishii, T; Kawamura, T; Tsuboi, N | 1 |
| Baek, SH; Dong, YG; Ihm, SH; Ke, YN; Ma, SP; Yuan, H | 1 |
| Ha, JW; Jung, HO; Park, JB; Rhee, MY | 1 |
| Higashi, Y; Hikita, K; Honda, M; Kawamoto, B; Muraoka, K; Saito, M; Sejima, T; Shimizu, S; Shimizu, T; Takenaka, A | 1 |
| Choi, DJ; Kim, DS; Kim, DW; Kim, JH; Lee, HY; Lee, SY; Park, CG; Park, JB; Park, SW; Rim, SJ; Shim, WJ; Shin, JH; Youn, HJ | 1 |
| Sapra, B; Sood, J; Tiwary, AK | 1 |
| Georgianos, PI; Liakopoulos, V; Zebekakis, PE | 1 |
| Chavan, RB; Chella, N; Lodagekar, A; Mannava, MKC; Nangia, AK; Shastri, NR; Yadav, B | 1 |
| Fu, J; Liu, W; Liu, Y | 1 |
| Chen, LL; Li, Y; Wang, JG; Xie, JH; Xu, SK; Zeng, WF | 1 |
| Hirata, T; Ishii, T; Kokuba, S; Nakamura, K; Shiohira, H; Tayag, JCS | 1 |
| Hu, L; Liu, G; Wei, Y | 1 |
| Tchernev, G | 1 |
1 review(s) available for valsartan and nifedipine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
9 trial(s) available for valsartan and nifedipine
| Article | Year |
|---|---|
Efficacy of various antihypertensive agents as evaluated by indices of vascular stiffness in elderly hypertensive patients.
Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Ankle; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Calcium Channel Blockers; Dihydropyridines; Female; Humans; Hypertension; Male; Nifedipine; Pulsatile Flow; Tetrazoles; Thiazepines; Treatment Outcome; Valine; Valsartan | 2003 |
Effects of valsartan and nifedipine coat-core on systemic arterial stiffness in hypertensive patients.
Topics: Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Blood Flow Velocity; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Controlled release nifedipine and valsartan combination therapy in patients with essential hypertension: the adalat CR and valsartan cost-effectiveness combination (ADVANCE-combi) study.
Topics: Adult; Aged; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cost-Benefit Analysis; Delayed-Action Preparations; Drug Costs; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Nifedipine; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
Angiotensin receptor blocker improves coronary flow velocity reserve in hypertensive patients: comparison with calcium channel blocker.
Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Blood Flow Velocity; Blood Pressure; Calcium Channel Blockers; Coronary Circulation; Echocardiography; Female; Humans; Hyperemia; Hypertension; Male; Middle Aged; Nifedipine; Tetrazoles; Valine; Valsartan | 2007 |
Improved blood pressure control with nifedipine GITS/valsartan combination versus high-dose valsartan monotherapy in mild-to-moderate hypertensive patients from Asia: results from the ADVISE study, a randomized trial.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Asian People; Blood Pressure; Comorbidity; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Prospective Studies; Tetrazoles; Valine; Valsartan; Young Adult | 2012 |
Randomized trial comparing the effects of a low-dose combination of nifedipine GITS and valsartan versus high-dose monotherapy on central hemodynamics in patients with inadequately controlled hypertension: FOCUS study.
Topics: Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Hemodynamics; Humans; Hypertension; Male; Manometry; Middle Aged; Nifedipine; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2014 |
Safety of the Up-titration of Nifedipine GITS and Valsartan or Low-dose Combination in Uncontrolled Hypertension: the FOCUS Study.
Topics: Adult; Aged; Antihypertensive Agents; Humans; Hypertension; Middle Aged; Nifedipine; Prospective Studies; Valsartan; Young Adult | 2016 |
Clinical effect and safety of nifedipine controlled-release tablets combined with valsartan in the treatment of primary hypertension.
Topics: Aged; Antihypertensive Agents; Calcium Channel Blockers; Delayed-Action Preparations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Nifedipine; Valsartan | 2019 |
Effects of the valsartan/amlodipine combination and nifedipine gastrointestinal therapeutic system monotherapy on brachial pulse pressure and radial augmentation index in hypertensive patients.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nifedipine; Tetrazoles; Treatment Outcome; Valsartan | 2021 |
24 other study(ies) available for valsartan and nifedipine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics | 2015 |
Antihyperglycemic action of angiotensin II receptor antagonist, valsartan, in streptozotocin-induced diabetic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Gene Expression; Glucose Tolerance Test; Glucose Transporter Type 4; Hyperglycemia; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Nicorandil; Nifedipine; Phosphoenolpyruvate Carboxykinase (GTP); Rats; Rats, Wistar; RNA, Messenger; Saralasin; Tetrazoles; Valine; Valsartan | 2003 |
Hematuria in a patient with class IV lupus nephritis.
Topics: Antihypertensive Agents; Biopsy; Cyclophosphamide; El Salvador; Female; Follow-Up Studies; Glomerular Basement Membrane; Glomerular Mesangium; Glucocorticoids; Hematuria; Hispanic or Latino; Humans; Hydrochlorothiazide; Hydroxychloroquine; Hypertension; Immunosuppressive Agents; Kidney Glomerulus; Lisinopril; Lupus Nephritis; Middle Aged; Nifedipine; Prednisone; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2006 |
Cost-effectiveness analysis: controlled-release nifedipine and valsartan combination therapy in patients with essential hypertension: the adalat CR and valsartan cost-effectiveness combination (ADVANCE-Combi) study.
Topics: Amlodipine; Cost-Benefit Analysis; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Japan; Nifedipine; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2008 |
AT(1) receptor blockers increase insulin-like growth factor-I production by stimulating sensory neurons in spontaneously hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Pressure; Calcitonin Gene-Related Peptide; Capsaicin; Cells, Cultured; Ganglia, Spinal; Hypertension; Imidazoles; Insulin-Like Growth Factor I; Kidney; Losartan; Male; Myocardium; Nifedipine; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; RNA, Messenger; Sensory Receptor Cells; Telmisartan; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2009 |
[CCB uptitration is superior to ARB uptitration in CKD patients who do not reach target blood pressure with ARB/CCB combined therapy].
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Calcium Channel Blockers; Chronic Disease; Drug Therapy, Combination; Glomerular Filtration Rate; Hypertension; Kidney Diseases; Nifedipine; Tetrazoles; Time Factors; Valine; Valsartan | 2010 |
Vesicovascular reflexes in the spontaneously hypertensive rat.
Topics: Animals; Antihypertensive Agents; Atherosclerosis; Blood Pressure; Blood Vessels; Epinephrine; Hypertension; Male; Myocardium; Nifedipine; Norepinephrine; Pulse Wave Analysis; Rats; Rats, Inbred SHR; Rats, Wistar; Reflex; Valsartan; Vasodilator Agents | 2016 |
Microemulsion Transdermal Formulation for Simultaneous Delivery of Valsartan and Nifedipine: Formulation by Design.
Topics: Administration, Cutaneous; Animals; Antihypertensive Agents; Chemistry, Pharmaceutical; Drug Compounding; Drug Delivery Systems; Emulsions; Excipients; Male; Nifedipine; Oils; Organ Culture Techniques; Particle Size; Rats; Skin Absorption; Surface-Active Agents; Valsartan | 2017 |
Low-dose combination therapy to control sustained ambulatory hypertension-Basic principles and future directions.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Nifedipine; Valsartan; Vascular Stiffness | 2019 |
Co amorphous valsartan nifedipine system: Preparation, characterization, in vitro and in vivo evaluation.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Calcium Channel Blockers; Drug Combinations; Drug Compounding; Drug Liberation; Female; Nifedipine; Rats, Sprague-Dawley; Valsartan | 2019 |
Effects of 5-fluorouracil Co-administration on Blood Pressure in Patients Maintained on Antihypertensives: a Retrospective Case Series.
Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Fluorouracil; Humans; Hypertension; Nifedipine; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2023 |
Therapeutic improvements of nifedipine controlled-release tablets combined with sacubitril valsartan on patients with diabetic nephropathy complicated with hypertension.
Topics: Biphenyl Compounds; Delayed-Action Preparations; Diabetes Mellitus; Diabetic Nephropathies; Drug Combinations; Humans; Hypertension; Nifedipine; Tetrazoles; Valsartan | 2023 |
NITROSAMINE CONTAMINATION WITHIN CARDIAC MULTIMEDICATION - SARTANS (VALSARTAN), CALCIUM CHANNEL BLOCKERS (AMLODIPINE AND NIFEDIPINE), AND ANTIARRHYTHMICS (PROPAFENONE) AS A SIGNIFICANT FACTOR IN THE DEVELOPMENT AND PROGRESSION OF MULTIPLE KERATINOCYTIC CA
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Anti-Arrhythmia Agents; Calcium Channel Blockers; Carcinogens; Humans; Keratoacanthoma; Neoplasms; Nifedipine; Nitrosamines; Propafenone; Shoulder; Surgical Flaps; Valsartan | 2023 |