valsartan has been researched along with amlodipine in 278 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (1.08) | 18.2507 |
| 2000's | 113 (40.65) | 29.6817 |
| 2010's | 137 (49.28) | 24.3611 |
| 2020's | 25 (8.99) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Bodin, F; Cardoni, O; Corea, L; Fogari, R; Innocenti, P; Meilenbrock, S; Porcellati, C; Provvidenza, M; Sullivan, J | 1 |
| Julius, S; Mann, J | 1 |
| Julius, S | 1 |
| Bertocchi, F; Bonaduce, D; Carretta, R; Condorelli, M; Fogari, R; Malacco, E; Mann, J; Palatini, P | 1 |
| Bertocchi, F; Carretta, R; Di, SS; Dorigatti, F; Malacco, E; Mann, J; Palatini, P | 1 |
| Dendorfer, A; Dodt, C; Handrock, R; Muck, P; Struck, J; Trübger, D; Weidinger, G | 1 |
| Viberti, G; Wheeldon, NM | 1 |
| Allen, TJ; Cao, Z; Cooper, ME; Davis, BJ; de Gasparo, M; Kawachi, H | 1 |
| Handrock, R; Schmieder, RE | 1 |
| Brunner, H; Ekman, S; Hansson, L; Julius, S; Kjeldsen, SE; Laragh, JH; McInnes, G; Platt, F; Schork, AM; Smith, B; Weber, M; Zanchetti, A | 1 |
| Delles, C; Handrock, R; Klingbeil, AU; Schmieder, RE; Schneider, MP; Weidinger, G | 1 |
| Borgnino, C; Capuano, V; Malacco, E; Palatini, P; Spagnuolo, V; Varì, N | 1 |
| Eguchi, K; Hoshide, S; Hoshide, Y; Ishikawa, J; Ishikawa, S; Kario, K; Morinari, M; Shimada, K | 1 |
| Franco, RJ; Goldflus, S; McQuitty, M; Oigman, W | 1 |
| Hukai, D; Ishii, C; Kanamori, T; Ohbayashi, Y; Ohnishi, M; Ohno, K; Okabayashi, T; Ozawa, T; Sakaguchi, T; Sichiri, G; Tanaka, T; Tsutamoto, T; Tsutsui, T; Wada, A; Yokohama, H | 1 |
| Delles, C; Handrock, R; Klingbeil, AU; Schäufele, T; Schmieder, RE; Schneider, MP | 1 |
| Ambrosia, GB; Caiazza, A; Malacco, E; Mugellini, A; Palatini, P; Santonastaso, M; Spagnuolo, V | 1 |
| Asada, A; Maeda, K; Nakamura, M; Watanabe, T; Yasunari, K; Yoshikawa, J | 1 |
| Lindholm, LH | 1 |
| Brunner, HR; Ekman, S; Hansson, L; Hua, T; Julius, S; Kjeldsen, SE; Laragh, J; McInnes, GT; Mitchell, L; Plat, F; Schork, A; Smith, B; Weber, M; Zanchetti, A | 1 |
| Brunner, HR; Ekman, S; Hansson, L; Hua, T; Julius, S; Kjeldsen, SE; Laragh, JH; McInnes, GT; Mitchell, L; Plat, F; Schork, MA; Smith, B; Weber, MA; Zanchetti, A | 1 |
| Epstein, M; Hollenberg, NK | 1 |
| Bernaud, C; Boivin, JM; Fay, R; Radauceanu, A; Zannad, F | 1 |
| Nilsson, PM | 1 |
| Sever, P | 1 |
| Zidek, W | 2 |
| Berk, BC; Bisognano, JD | 1 |
| Einecke, D | 1 |
| Bertocchi, F; Dorigatti, F; Ferrara, R; Mugellini, A; Palatini, P; Spagnuolo, V; Varì, N | 1 |
| Strauss, M; Verma, S | 1 |
| Hedner, T; Himmelmann, A; Kjeldsen, SE | 1 |
| Jackson, G | 1 |
| Efstathiou, S; Makris, T; Manolis, A; Papavasiliou, M; Stergiou, GS | 1 |
| Weber, MA | 1 |
| Brandão, AA; Heintz, D; Kandra, A; Khder, Y; Ruilope, LM; Santonastaso, M; Stolt, P | 1 |
| Kostis, WJ; Wilson, AC | 1 |
| Bönner, G; Heintz, D; Kandra, A; Khder, Y; Malacco, E; Ruilope, LM | 1 |
| Daley, W; Ferdinand, KC; Flack, JM; Jamerson, KA; Weir, MR; Zelenkofske, S | 1 |
| Arosio, E; De Marchi, S; Lechi, A; Prior, M; Rigoni, A | 1 |
| Coca, A; Ekman, S; Girerd, X; Hua, T; Jamerson, K; Julius, S; Kjeldsen, SE; Larochelle, P; MacDonald, TM; Mancia, G; McInnes, GT; Schmieder, RE; Schork, MA; Stolt, P; Viskoper, R; Weber, MA; Widimský, J; Zanchetti, A | 1 |
| Aryana, A; Hilleman, DE; Maciejewski, S; Mohiuddin, SM; Mooss, AN; Packard, KA; Reyes, AP | 1 |
| Ichihara, A; Kaneshiro, Y; Sakoda, M; Takemitsu, T | 1 |
| Amerena, J; Balazovjech, I; Brunner, HR; Cassel, G; Herczeg, B; Hua, TA; Julius, S; Kjeldsen, SE; Koylan, N; Laragh, J; Magometschnigg, D; Majahalme, S; Martinez, F; McInnes, GT; Oigman, W; Schork, MA; Seabra Gomes, R; Weber, MA; Zanchetti, A; Zhu, JR | 1 |
| Higaki, J; Okura, T | 1 |
| Barker, TA; Berk, BC; Kennedy, AJ; Korshunov, VA; Massett, MP; Mohan, AM | 1 |
| Ruilope, LM; Zanchetti, A | 1 |
| Battegay, E; Calvo-Vargas, C; Cieśliński, A; Degaute, JP; Holwerda, NJ; Hua, T; Julius, S; Kjeldsen, S; Kobalava, J; Laragh, JH; McInnes, GT; Pedersen, OL; Plat, F; Rudyatmoko, FP; Siamopoulos, KC; Störset, O; Weber, M; Zanchetti, A | 1 |
| Aslam, S; Leone, A; Santha, T; Wilcox, C | 1 |
| Bizot, MN; Denouel, J; Dieterich, HA; Dole, WP; Kemp, C; Vaidyanathan, S; Valencia, J; Yeh, CM; Zhao, C | 1 |
| Zoccali, C | 1 |
| Albini, TA; Foroozan, R; Lakhanpal, RR; Lopez, GA; McPherson, AR | 1 |
| Derosa, G; Fogari, E; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A | 1 |
| Birkenhäger, WH; Hansen, TW; Staessen, JA | 1 |
| Høegholm, A; Julius, S; Kjeldsen, SE; Mancia, G; Nielsen, ES; Pedersen, OL; Pickering, T; Refsgaard, J; Weber, M | 1 |
| Edelsberg, J; Jamerson, K; Khan, ZM; Kjeldsen, SE; Oster, G; Vincze, G; Weycker, D | 1 |
| Assouline, L; de Champlain, J; Dubé, B; Karas, M; Larochelle, P; LeBlanc, AR; Nadeau, R | 1 |
| Kashiwagi, A; Maegawa, H; Sawaguchi, M; Uzu, T | 2 |
| Acikel, C; Caglar, K; Celik, T; Eyileten, T; Oguz, Y; Sonmez, A; Vural, A; Yavuz, I; Yenicesu, M; Yilmaz, MI | 1 |
| Itoh, Y; Mori, Y; Tajima, N | 1 |
| Chiang, YT; Fomina, I; Gamboa, R; Glazes, R; Kaczor, J; Kargiannis, S; Poldermans, D; Wernsing, M; Yen, J | 1 |
| Bakris, GL; Glazer, R; Philipp, T; Smith, TR; Vaisse, B; Wernsing, M; Yen, J | 1 |
| Glazer, R; Jin, J; Philipp, T; Pospiech, R; Schneider, H; Smith, TR; Wernsing, M; Yen, J | 1 |
| Dong, YF; Ichijo, H; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Ogawa, H; Shintaku, H; Tokutomi, Y; Yamamoto, E; Yamashita, T | 1 |
| Campestrini, J; Dole, K; Dole, WP; He, YL; Howard, D; Ligueros-Saylan, M; Marion, A; Pommier, F; Sabo, R; Sunkara, G; Wang, Y; Zhao, C | 1 |
| Krzesinski, JM; Scheen, AJ | 1 |
| Plosker, GL; Robinson, DM | 1 |
| Hua, TA; Julius, S; Kjeldsen, SE; McInnes, GT; Schmieder, RE; Zanchetti, A | 1 |
| Allemann, Y; Barbier, M; Ferber, P; Fraile, B; Izzo, JL; Lambert, M | 1 |
| Corradi, L; Derosa, G; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Daimon, M; Fujita, M; Komuro, I; Kuwabara, Y; Mizuma, H; Nakayama, K; Narumi, H; Shindo, S | 1 |
| Asai, S; Ishikawa, K; Nishida, Y; Sugahara-Kobayashi, M; Takahashi, Y | 1 |
| Hirooka, Y; Ito, K; Kimura, Y; Sagara, Y; Sunagawa, K | 1 |
| Botha, J; DeAngelis, L; Ferber, P; Kandra, A; Karalliedde, J; Mirenda, V; Smith, A; Viberti, G | 1 |
| Croce, G; Desideri, G; Ferri, C | 1 |
| Ansari, A; Brachmann, J; Handrock, R; Klebs, S; Mahla, G | 1 |
| Aksnes, TA; Hua, TA; Julius, S; Kjeldsen, SE; Rostrup, M; Störset, O | 1 |
| Corradi, L; Derosa, G; Ferrari, I; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Santoro, T; Zoppi, A | 1 |
| Ferguson, KL; Greller, HA; Hoffman, RS; Nelson, LS; Smith, SW | 1 |
| Anthony Schork, M; Coca, A; Girerd, X; Hua, TA; Jamerson, K; Julius, S; Kjeldsen, SE; Larochelle, P; Macdonald, T; Mancia, G; McInnes, GT; Schmieder, RE; Viskoper, R; Weber, MA; Widimsky, J; Zanchetti, A | 1 |
| Mourad, JJ; Waeber, B | 1 |
| Brixner, DI; Jackson, KC; Keskinaslan, A; Nelson, RE; Sheng, X | 1 |
| Fujikawa, K; Saito, I; Saruta, T | 1 |
| Corradi, L; Derosa, G; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Santoro, T; Zoppi, A | 1 |
| Belousov, DIu; Belousov, IuB; Shestakova, MV | 1 |
| Glazer, RD; Kavoliuniene, A; Miglinas, M; Prak, H; Sinkiewicz, W; Wernsing, M; Yen, J | 1 |
| Ansari, A; Braun, N; Handrock, R; Klebs, S; Ulmer, HJ | 1 |
| Akpinar, E; Brunel, P; Calvo, C; Keeling, L; Salvetti, A; Schrader, J; Weisskopf, M | 1 |
| Edelsberg, J; Kartashov, A; Keskinaslan, A; Levy, DG; Oster, G; Weycker, D | 1 |
| Borbas, E; Handrock, R; Klebs, S; Schaetzl, R; Trenkwalder, P | 1 |
| Ram, CV | 1 |
| Glazer, RD; Philipp, T; Pospiech, R; Zhao, Y | 1 |
| Ichihara, A; Itoh, H; Kaneshiro, Y; Kinouchi, K; Kurauchi-Mito, A; Sakoda, M | 1 |
| Mullangi, R; Ramani, AV; Sengupta, P | 1 |
| Black, HR; Lacourcière, Y; Purkayastha, D; Samuel, R; Wright, JT; Zappe, D | 2 |
| Black, HR | 1 |
| Calhoun, DA; Chiang, YT; Glazer, RD; Lacourcière, Y | 1 |
| Flack, JM; Hilkert, R | 1 |
| Vivencio, B | 1 |
| Glazer, RD; Macarie, CE; Romanova, J; Schunkert, H; Vintila, MM; Wernsing, M; Yen, J | 1 |
| Frampton, JE; Scott, LJ | 1 |
| Ferber, P; Papst, CC; Zappe, D | 1 |
| Deeks, ED | 1 |
| Divchev, D; Grothusen, A; Luchtefeld, M; Schieffer, B | 1 |
| Chen, X; Dong, J; Jiang, L; Jiang, W; So, Y; Xin, H | 1 |
| Calhoun, DA; Crikelair, NA; Glazer, RD; Yen, J | 1 |
| Huang, J; Ke, YN; Zhu, JR | 1 |
| Corradi, L; Derosa, G; Fogari, R; Malamani, G; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Derosa, G; Fogari, R; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Achouba, A; Boutouyrie, P; Laurent, S; Trunet, P | 1 |
| Cagnoni, F; D'Ospina, A; Demichele, E; Destro, M; Peros, E; Preti, P; Ricci, AR; Zaninelli, A | 1 |
| Kondo, T; Maeda, K; Matsushita, K; Muramatsu, T; Murohara, T; Shintani, S | 1 |
| Blanco-Colio, LM; Carrero, JJ; Celik, T; Egido, J; Eyileten, T; Martín-Ventura, JL; Moreno, JA; Saglam, M; Sonmez, A; Yaman, H; Yenicesu, M; Yilmaz, MI | 1 |
| Cardenas, P; Hong, H; Ke, Y; Wang, R; Zhang, Y; Zhu, D; Zhu, J | 1 |
| Deedwania, PC; Egan, BM; Jialal, I; Ofili, EO; Purkayastha, D; Raij, L; Samuel, R; Sowers, JR; Zappe, DH | 1 |
| Ayala, DE; Fernández, JR; Fontao, MJ; Hermida, RC; Mojón, A | 1 |
| Derosa, G; Ferrari, I; Fogari, R; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Desilva, VR; Enomoto, D; Higaki, J; Irita, J; Jotoku, M; Kurata, M; Miyoshi, K; Nagao, T; Okura, T | 1 |
| Hilleman, DE; Malesker, MA | 1 |
| Bilo, G; Mancia, G; Parati, G; Schumacher, H | 1 |
| Ayalasomayajula, S; Bhad, P; Jarugula, V; Karan, R; Leon, S; Riviere, GJ; Sunkara, G | 1 |
| Crikelair, N; Destro, M; Glazer, R; Yen, J | 1 |
| Belal, TS; Shaalan, RA | 1 |
| Aritomi, S; Koganei, H; Konda, T; Mitsui, A; Nitta, K; Ogawa, T; Wagatsuma, H | 1 |
| Fujita, M; Komuro, I; Kuwabara, Y; Mizuma, H; Narumi, H; Shindo, S; Takano, H | 1 |
| Giles, T; Hilkert, R; Ofili, EO; Oparil, S; Pitt, B; Samuel, R; Seifu, Y; Sowers, JR | 1 |
| Barrios, V; Escobar, C | 1 |
| Chazova, IE; Dongre, N; Vigdorchik, AV | 1 |
| Calhoun, DA; Crikelair, N; Glazer, RD; Lacourcière, Y; Yen, J | 1 |
| Aritomi, S; Konda, T; Niinuma, K; Nitta, K; Ogawa, T | 2 |
| Bekki, H; Fukami, K; Homma, T; Nakata, M; Nohara, M; Okuda, S; Sone, M; Yamagishi, S; Yamamoto, K | 1 |
| Curt, V; Hao, YM; Huang, J; Sun, NL; Tu, Y; Zhang, Y; Zhu, JR | 1 |
| Aderibigbe, A; Anisiuba, BC; Ba, SA; Boombhi, HJ; Ijoma, CK; Kamdem, MK; Kaptue, J; Kingue, S; Kolo, PM; Lemogoum, D; M'buyamba-Kabangu, JR; Mipinda, JB; Ndiaye, MB; Odili, AN; Omotoso, BA; Richart, T; Staessen, JA; Thijs, L; Ulasi, II | 1 |
| Higashi, K; Hiroo, K; Kushiyama, T; Oda, T; Yamamoto, K | 1 |
| Andrews, LM; Baser, O; Wang, L; Xie, L | 1 |
| Duprez, D; Ferdinand, KC; Purkayastha, D; Samuel, R; Wright, RF | 1 |
| Dong, YF; Kataoka, K; Kim-Mitsuyama, S; Koibuchi, N; Nakamura, T; Nako, H; Ogawa, H; Sueta, D; Tokutomi, Y; Toyama, K; Yamamoto, E | 1 |
| Bagmanova, NKh; Fediunina, EIu; Karaulova, IuL; Kobalava, ZhD; Kotovskaia, IuV | 1 |
| Egan, BM; Purkayastha, D; Raij, L; Samuel, R; Sowers, JR; Zappe, DH | 1 |
| Hasegawa, H; Kobayashi, Y; Komuro, I; Kuwabara, Y; Mizuma, H; Narumi, H; Shindo, S; Takano, H | 1 |
| Chrysant, SG | 1 |
| Christogiannis, LG; Elisaf, MS; Kostapanos, MS; Milionis, HJ; Tellis, CC; Tselepis, AD | 1 |
| Cai, J; Cheng, K; Huang, Z; Ming, Y; Yang, G; Ye, Q; Yuan, H; Zhou, P; Zuo, X | 1 |
| Duprez, D; Ferdinand, K; Purkayastha, D; Samuel, R; Wright, R | 1 |
| Ichimiya, S; Ikeda, N; Kondo, T; Maeda, K; Matsushita, K; Muramatsu, T; Murohara, T; Ohno, M; Shintani, S; Sone, T; Watarai, M; Yamashita, K | 1 |
| Ofili, EO; Purkayastha, D; Samuel, R; Sowers, JR; Zappe, DH | 1 |
| Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A | 1 |
| Pancholi, SS; Sharma, RN | 1 |
| Sun, CX; Tao, CW; Wu, ZB; Yu, QG; Zhang, Y | 1 |
| Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Ikeda, M; Ohta, M; Tajiri, Y; Yamato, H | 1 |
| Barrios, V; de la Sierra, A | 1 |
| Gao, P; Grosso, A; Sun, N; Wang, R; Yang, K; Zhang, Y; Zhu, D | 1 |
| Chen, JF; Hung, YJ; Lee, IT; Lee, WJ; Sheu, WH; Wang, CY | 2 |
| Kaynar, K; Konca, C; Ozkan, G; Ulusoy, S | 1 |
| Chen, CS; Cheng, SM; Hsieh, CM; Huang, LC; Huang, SC; Mar, GY; Ueng, KC | 1 |
| Brunner, HR; Hua, TA; Jia, Y; Julius, S; Kjeldsen, SE; Mancia, G; McInnes, GT; Schork, A; Weber, MA; Zanchetti, A; Zappe, DH | 1 |
| Dohi, K; Hiraoka, N; Hoshino, K; Ito, M; Kitai, T; Kumagai, N; Nakamori, S; Nakamura, M; Okamoto, S; Onishi, K; Oota, M; Ueda, Y; Yamada, T; Yazu, T | 1 |
| Baek, I; Haesler, E; Hayoz, D; Joly, MP; Kandra, A; Mazzolai, L; Meyer, MA; Periard, D; Zappe, DH | 1 |
| Arslan, E; Ay, SA; Balta, S; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Sağlam, K; Turker, T; Unlu, M; Yaman, H | 1 |
| Akhan, M; Arslan, E; Arslan, Z; Ay, SA; Balta, S; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Saglam, K; Sarlak, H | 1 |
| Goto, SN; Mizuno, Y; Takagi, H; Umemoto, T; Yamamoto, H | 1 |
| Huang, J; Huang, Y; Wang, T | 1 |
| Arslan, Z; Balta, S; Bozoglu, E; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Kocak, N; Kurt, O; Naharci, I; Sarlak, H; Seyit Ahmet, AY | 1 |
| Kothari, C; Mehta, P; Sharma, M; Sherikar, O | 1 |
| Akhan, M; Altun, B; Arslan, E; Ay, SA; Balta, S; Bulucu, F; Cakar, M; Demirkol, S; Karaman, M; Koc, B; Kurt, O; Unlu, M | 1 |
| Aoyama, T; Goto, M; Goto, N; Hiei, K; Iwasa, M; Kawai, N; Kida, K; Kobayashi, H; Kojima, S; Minagawa, T; Minatoguchi, S; Oda, M; Sugishita, F; Takai, K; Tanaka, R; Watanabe, I; Yamamoto, N; Yasue, T | 1 |
| Freytag, S; Hagendorff, A; Klebs, S; Müller, A | 1 |
| Arslan, E; Ay, SA; Balta, S; Bozoglu, E; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Kurt, O; Naharci, MI | 1 |
| Aksenova, AV; Chazova, IE; Elfimova, EM; Galitsin, PV; Litvin, AY; Rogoza, AN; Sukmarova, ZN | 1 |
| Eckert, S; Freytag, SB; Klebs, SH; Müller, A | 1 |
| Calhoun, DA; Crikelair, N; Glazer, RD; Jia, Y; Lacourcière, Y | 1 |
| Darwish, HW; El-Zeany, BA; Hassan, SA; Salem, MY | 2 |
| Anisiuba, BC; Ba, SA; Boombhi, HJ; Ezeala-Adikaibe, B; Ijoma, CK; Jacobs, L; Kaptue, J; Kingue, S; Kolo, PM; Lemogoum, D; M'Buyamba-Kabangu, JR; Mipinda, JB; Ndiaye, MB; Odili, A; Omotoso, BA; Osakwe, CE; Staessen, JA; Thijs, L; Ulasi, II | 1 |
| Bahng, MY; Chae, D; Kim, Y; Lee, D; Park, K; Roh, H; Son, H; Son, M | 1 |
| Berktaş, M; Boyacı, B; Kızılırmak, P; Yalçın, MR | 1 |
| Gnudi, L; Hill, B; Karalliedde, J; Maltese, G; Viberti, G | 1 |
| Kondo, T; Maeda, K; Matsushita, K; Muramatsu, T; Murohara, T; Nagahiro, T; Shintani, S; Yamashita, K | 1 |
| Akasaka, H; Miura, T; Saitoh, S; Shimamoto, K; Yoshida, H | 1 |
| Ar, I; Ilerigelen, B; Kızılırmak, P | 1 |
| Kartashova, EA; Romantsov, MG; Sarvilina, IV | 1 |
| Izumikawa, Y; Kato, H; Kojima, K; Kubo, E; Nagura, M; Nosaka, H; Shima, T; Shimada, M; Shiraishi, T; Tanemoto, M; Tomioka, S; Uchida, S; Ueda, S; Yano, H | 1 |
| Kobalava, ZhD; Kotovskaia, IuV; Kravtsova, OA; Lobzhanidze, TV | 1 |
| Harada, E; Hattori, T; Matsuura, N; Murohara, T; Nagasawa, K; Nagata, K; Niinuma, K; Takahashi, K; Takatsu, M; Watanabe, S | 1 |
| Greenwood, JP; Negrou, K; Oliver, JJ; Plein, S; Ripley, DP; Struthers, AD; Worthy, G | 1 |
| Andrikou, I; Aragiannis, D; Bilo, G; Dimitriadis, K; Filis, K; Kasiakogias, A; Parati, G; Sideris, S; Stefanadis, C; Thomopoulos, C; Tsiachris, D; Tsioufis, C | 1 |
| Amodeo, C; Asmar, R; Chazova, IE; Gamba, MA; Mancia, G; Mourad, JJ; Puig, JG; Taddei, S | 1 |
| Ahmet Ay, S; Balta, S; Celık, T; Demırkol, S; Dınc, M; Fıcı, F; Grassı, G; Iyısoy, A; Karaman, M; Kılıc, S; Kurt, G; Ozturk, C; Quartı-Trevano, F; Tas, A; Unal, HU; Yılmaz, MI | 1 |
| Hegazy, MA; Lotfy, HM; Mohamed, EH; Mowaka, S | 2 |
| Assaad-Khalil, SH; Cho, B; DiTommaso, S; Kitchlew, AR; Najem, R; Shete, A; Sison, J; Ueng, KC | 1 |
| Coufal, P; Janečková, L; Jedlička, A; Vojta, J | 1 |
| Atanasovska, E; Cekovska, S; Gjorgjievska, K; Jurhar-Pavlova, M; Pavlovska, K; Zafirov, D; Zendelovska, D | 1 |
| Ayad, MF; El-Kosasy, AM; Sheta, AI; Tawakkol, SM | 1 |
| Ebeid, W; El-Bagary, R; Elkady, E; Elzahr, A; Patonay, G; Salim, M | 1 |
| Anraku, Y; Inami, S; Inoue, T; Kato, T; Kikegawa, Y; Nakamoto, A; Node, K; Suzuki, A; Toyoda, S; Tsukada, K | 1 |
| Adachi, S; Fujisawa, K; Inoue, T; Kusumoto, T; Miura, S; Motozato, K; Saku, K; Shiga, Y | 1 |
| Cole, JB; Laes, JR; Williams, DM | 1 |
| Chen, W; Kahler, KH; Machnicki, G; Ong, SH; Wei, ZJ | 1 |
| Bangalore, S; Berge, E; Holzhauer, B; Hua, TA; Julius, S; Kjeldsen, SE; Mancia, G; Messerli, FH; Weber, MA; Zanchetti, A; Zappe, D | 1 |
| Abdillah, A; Kalim, H; Setiawati, A | 1 |
| Aksnes, TA; Holzhauer, B; Hua, TA; Julius, S; Kjeldsen, SE; Rostrup, M | 1 |
| Akkaya, N; Cakmak, M; Çelik, HT; Demircelik, B; Erdamar, H; Gok, S; Kazanci, F; Yigitoglu, R | 1 |
| Greeley, M; Hsiao, HL; Langenickel, TH; Pal, P; Rajman, I; Rebello, S; Roberts, J; Sunkara, G; Zhou, W | 1 |
| Akçay, S; Aksoy, F; Erdoğan, D; Ersoy, İ; İçli, A; Özaydın, M; Yücel, H | 1 |
| Heo, YA; Holford, N; Kim, Y; Park, K; Son, M | 1 |
| Fujii, M; Ichikawa, M; Imagawa, M; Ishizuka, T; Kaeriyama, S; Konoshita, T; Makino, Y; Nakamura, H; Nakaya, T; Sato, S; Suzuki, J; Urabe, M; Wakahara, S; Yamada, M; Yamamoto, K; Zenimaru, Y | 1 |
| Hammad, MA; Mohamed, AA; Mohamed, AI; Omar, MA | 1 |
| Hafeez, K; Jia, Y; Sibulo, A; Wang, JG; Yukisada, K; Zhang, J | 1 |
| Chen, X; Liu, K; Liu, Q; Shi, D; Shi, R | 1 |
| Casian, T; De Beer, T; Reznek, A; Tomuță, I; Van Renterghem, J; Vonica-Gligor, AL | 1 |
| Moon, JS; Won, KC | 1 |
| Ahn, YB; Choi, SH; Han, SJ; Jang, HC; Kim, DJ; Kim, HJ; Kim, HY; Kim, NH; Kim, SH; Kim, TH; Kim, YH; Ko, SH; Lee, KW; Lim, S; Seo, JA; Shin, DH | 1 |
| Büker, E; Dinç, E; Ertekin, ZC | 1 |
| Doka, G; Klimas, J; Kralova, E; Krenek, P; Potucek, P; Radik, M | 1 |
| Bridgeman, MB; Dalal, KS | 1 |
| Albrecht, D; Blaak, EE; Engeli, S; Goossens, GH; Haufe, S; Havekes, B; Heise, T; Jax, T; Jordan, J; Langenickel, TH; May, M; Pal, P; Stinkens, R; Tegtbur, U | 1 |
| Berge, E; Hua, TA; Julius, S; Kjeldsen, SE; Liestøl, K; Mancia, G; Mehlum, MH; Parati, G; Rothwell, PM; Weber, MA | 1 |
| Albrecht, D; Blaak, EE; Engeli, S; Goossens, GH; Hartmann, N; Havekes, B; Heise, T; Jax, T; Jocken, JW; Jordan, J; Kaiser, S; Langenickel, TH; Letzkus, M; May, M; Schaper, N; Schindler, C; Stinkens, R; van der Kolk, BW | 1 |
| Shen, T; Wang, J; Yu, J; Yu, Y | 1 |
| Laurent, S; Mancia, G; Poulter, N | 1 |
| Bafor, EE; Bolanle, IO; Omogbai, EKI | 1 |
| Břicháč, J; Douša, M; Gibala, P; Kalášek, S; Kalužíková, A; Štefko, M; Tkadlecová, M | 1 |
| Gegeshidze, N; Kapetivadze, V; Lazashvili, T; Maglapheridze, Z; Tabukashvili, R; Tchaava, K | 1 |
| Presta, V; Tocci, G | 1 |
| Georgianos, PI; Liakopoulos, V; Zebekakis, PE | 1 |
| Cho, S; Gwon, MR; Kang, WY; Kim, BK; Lee, HW; Ohk, B; Seong, SJ; Yang, DH; Yoon, YR | 1 |
| Asmar, R; Brzozowska-Villatte, R; de Champvallins, M; Dominiczak, AF | 1 |
| Habara, M; Haraguchi, T; Ikezaki, H; Kojima, H; Nakamura, S; Uchida, T; Yoshida, M | 1 |
| Kim, JR; Kim, S; Ko, JW | 1 |
| Hebibovic, S; Jatic, Z; Rustempasic, E; Skopljak, A; Sukalo, A; Valjevac, A | 1 |
| Bianco, HT; Ferreira, CES; Figueiredo Neto, AM; Fonseca, FAH; França, CN; Izar, MCO; Kato, JT; Massunaga, ND; Póvoa, RMS | 1 |
| Hanada, H; Higaki, J; Higashiura, K; Horio, T; Hosomi, N; Igase, M; Ishimitsu, T; Iwashima, Y; Kamide, K; Katabuchi, R; Kato, J; Kawano, Y; Kojima, S; Komai, N; Matsuura, H; Miki, T; Miwa, Y; Miyata, T; Morimoto, S; Nakahama, H; Nakahashi, T; Nakamura, S; Ohta, Y; Oukura, T; Rakugi, H; Sasaguri, T; Sase, K; Shimamoto, K; Shinagawa, T; Soma, M; Sugimoto, K; Takeda, K; Takiuchi, S; Tomohiro Katsuya, T; Tsuchihashi, T; Ueno, M; Yoshihara, F | 1 |
| Kario, K; Kurose, Y; Matsuda, S; Nagahama, S; Sugii, H; Suzuki, N; Teshima, T | 2 |
| Berge, E; Julius, S; Kjeldsen, SE; Liestøl, K; Mancia, G; Mehlum, MH; Parati, G; Rothwell, PM; Weber, MA; Wyller, TB | 1 |
| Khairat, I; Khedr, L; Werida, R | 1 |
| Abdul, A; Pathan, MAAK; Raut, S; Shaikh, JSA | 1 |
| Chen, LC; Chiang, CE; Leu, HB; Lu, TM; Wang, KL; Yu, WC | 1 |
| Bots, ML; Groenland, EH; Spiering, W; van der Elst, KCM; van Kleef, MEAM; Visseren, FLJ | 1 |
| Ahmed, HM; Belal, TS; El Yazbi, FA; Elonsy, SM; Shaalan, RA | 1 |
| Abousalih, FZ; Azougagh, M; Benchekroun, YH; Bennani, I; Bouatia, M; El Karbane, M; Saffaj, T | 1 |
| Chen, LL; Li, Y; Wang, JG; Xie, JH; Xu, SK; Zeng, WF | 1 |
| Chan, TH; Tsoi, MF; Yung Cheung, BM | 1 |
| Chen, W; Hua, Z; Li, Y; Wang, Y; Zhu, Y | 1 |
| Abdelkawy, M; El-Hanboushy, S; Fayez, YM; Lotfy, HM; Marzouk, HM | 1 |
| Chou, CL; Fang, TC; Li, CH | 1 |
| Ahmad, A; Alama, MN; Alharthi, TS; Alkreathy, HM; Alluhabi, SI; Alqarni, F; Alrafiah, AR; Damanhouri, ZA | 1 |
| Blettenberg, J; Böhm, M; Gillessen, A; Mevius, A; Predel, HG; Randerath, O; Schmieder, RE; Wassmann, S; Weisser, B; Wilke, T | 1 |
| Abdelrahim, MEA; Hanna, SM; Mahmoud, HB; Rabea, HM | 1 |
| Su, F; Xia, Q | 1 |
| Hirata, T; Ishii, T; Kokuba, S; Nakamura, K; Shiohira, H; Tayag, JCS | 1 |
| Liang, H; Tang, T; Xie, M | 1 |
| Tchernev, G | 3 |
20 review(s) available for valsartan and amlodipine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Long-term potential of angiotensin receptor blockade for cardiovascular protection in hypertension: the VALUE trial. Valsartan Antihypertensive Long-term Use Evaluation.
Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 1999 |
The VALUE trial: a commentary.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Administration Schedule; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
[VALUE].
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Double-Blind Method; Endpoint Determination; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Randomized Controlled Trials as Topic; Risk; Tetrazoles; Valine; Valsartan | 2006 |
Asymmetric dimethylarginine in end-stage renal disease patients: a biomarker modifiable by calcium blockade and angiotensin II antagonism?
Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Arginine; Biomarkers; Calcium; Calcium Channel Blockers; Humans; Kidney Failure, Chronic; Risk Factors; Tetrazoles; Valine; Valsartan | 2006 |
[A first drug combination for the treatment of arterial hypertension with a calcium channel antagonist (amlodipine besylate) and an angiotensin receptor blocker (valsartan): Exforge].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Drug Combinations; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 2007 |
Amlodipine/Valsartan: fixed-dose combination in hypertension.
Topics: Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Drug Combinations; Drug Synergism; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 2008 |
Role of combination therapy in the treatment of hypertension: focus on valsartan plus amlodipine.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hypertension; Life Style; Tetrazoles; Valine; Valsartan | 2008 |
Antihypertensive efficacy of olmesartan medoxomil or valsartan in combination with amlodipine: a review of factorial-design studies.
Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Olmesartan Medoxomil; Placebos; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2009 |
Single-pill combination of amlodipine and valsartan in the management of hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Humans; Hypertension; Patient Compliance; Tetrazoles; Valine; Valsartan | 2009 |
Amlodipine/valsartan single-pill combination: a review of its use in the management of hypertension.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Drug Interactions; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2009 |
Angiotensin II type 1 receptor blockade: high hopes sent back to reality?
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Consensus; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Follow-Up Studies; Heart Failure; Hospitalization; Humans; Hypertension; Hypertrophy, Left Ventricular; Middle Aged; Practice Guidelines as Topic; Primary Prevention; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Factors; Saralasin; Secondary Prevention; Stroke; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2009 |
Evaluating 24-h antihypertensive efficacy by the smoothness index: a meta-analysis of an ambulatory blood pressure monitoring database.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Databases, Factual; Female; Humans; Losartan; Male; Ramipril; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Valsartan-amlodipine-hydrochlorothiazide: the definitive fixed combination?
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Medication Adherence; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Single-pill triple-combination therapy: an alternative to multiple-drug treatment of hypertension.
Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Design; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Olmesartan Medoxomil; Practice Guidelines as Topic; Practice Patterns, Physicians'; Tetrazoles; Valine; Valsartan | 2011 |
Blood pressure control with angiotensin receptor blocker-based three-drug combinations: key trials.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2012 |
Effects of telmisartan therapy on interleukin-6 and tumor necrosis factor-alpha levels: a meta-analysis of randomized controlled trials.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Confidence Intervals; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Hypertension, Renal; Imidazoles; Interleukin-6; Obesity; Prospective Studies; Publication Bias; Randomized Controlled Trials as Topic; Stents; Telmisartan; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan | 2013 |
Meta-analysis of three observational studies of amlodipine/valsartan in hypertensive patients with additional risk factors.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Obesity, Abdominal; Risk Factors; Tetrazoles; Valine; Valsartan | 2013 |
Plasma Trough Concentrations of Antihypertensive Drugs for the Assessment of Treatment Adherence: A Meta-Analysis.
Topics: Amlodipine; Antihypertensive Agents; Humans; Hydrochlorothiazide; Hypertension; Treatment Adherence and Compliance; Valsartan | 2021 |
Efficacy of single-pill combination in uncontrolled essential hypertension: A systematic review and network meta-analysis.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Network Meta-Analysis; Telmisartan; Tetrazoles; Valine; Valsartan | 2023 |
145 trial(s) available for valsartan and amlodipine
| Article | Year |
|---|---|
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: a comparative study of the efficacy and safety against amlodipine.
Topics: Adult; Aged; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Dizziness; Double-Blind Method; Drug Administration Schedule; Edema; Female; Headache; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1996 |
The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial of cardiovascular events in hypertension. Rationale and design.
Topics: Aged; Amlodipine; Angiotensin II; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Prospective Studies; Research Design; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 1998 |
Long-term potential of angiotensin receptor blockade for cardiovascular protection in hypertension: the VALUE trial. Valsartan Antihypertensive Long-term Use Evaluation.
Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 1999 |
A multicenter, randomized double-blind study of valsartan/hydrochlorothiazide combination versus amlodipine in patients with mild to moderate hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2001 |
Trough:peak ratio and smoothness index in the evaluation of 24-h blood pressure control in hypertension: a comparative study between valsartan/hydrochlorothiazide combination and amlodipine.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Valine; Valsartan | 2002 |
Effects of selective angiotensin II receptor blockade on sympathetic nerve activity in primary hypertensive subjects.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Muscle, Skeletal; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2002 |
Microalbuminuria reduction with valsartan in patients with type 2 diabetes mellitus: a blood pressure-independent effect.
Topics: Adult; Aged; Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2002 |
[Control of systolic blood pressure in the VALUE trial after 12 months].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Double-Blind Method; Europe; Female; Germany; Humans; Hypertension; Male; Middle Aged; Prognosis; Reference Standards; Risk Factors; Tetrazoles; Valine; Valsartan | 2003 |
VALUE trial: Long-term blood pressure trends in 13,449 patients with hypertension and high cardiovascular risk.
Topics: Algorithms; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Cohort Studies; Double-Blind Method; Drug Utilization; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Risk; Tetrazoles; Valine; Valsartan | 2003 |
Direct comparison of the effects of valsartan and amlodipine on renal hemodynamics in human essential hypertension.
Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Glomerular Filtration Rate; Humans; Hypertension; Microcirculation; Middle Aged; Renal Circulation; Tetrazoles; Valine; Valsartan | 2003 |
A randomized, double-blind, active-controlled, parallel-group comparison of valsartan and amlodipine in the treatment of isolated systolic hypertension in elderly patients: the Val-Syst study.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Valine; Valsartan | 2003 |
Comparison of valsartan and amlodipine on ambulatory and morning blood pressure in hypertensive patients.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chronotherapy; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Efficacy and tolerability of the combination valsartan/hydrochlorothiazide compared with amlodipine in a mild-to-moderately hypertensive Brazilian population.
Topics: Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brazil; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Racial Groups; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2003 |
Effect of an angiotensin II type 1 receptor blocker, valsartan, on neurohumoral factors in patients with hypertension: comparison with a long-acting calcium channel antagonist, amlodipine.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Coronary Disease; Delayed-Action Preparations; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Neurotransmitter Agents; Norepinephrine; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors; Valine; Valsartan | 2003 |
Comparison of the effects on 24-h ambulatory blood pressure of valsartan and amlodipine, alone or in combination with a low-dose diuretic, in elderly patients with isolated systolic hypertension (Val-syst Study).
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2004 |
Comparative effects of valsartan versus amlodipine on left ventricular mass and reactive oxygen species formation by monocytes in hypertensive patients with left ventricular hypertrophy.
Topics: Amlodipine; Antihypertensive Agents; Cross-Sectional Studies; Double-Blind Method; Echocardiography; Female; Flow Cytometry; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Monocytes; Prospective Studies; Reactive Oxygen Species; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diuretics; Double-Blind Method; Endpoint Determination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Factors; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Differential time effect profiles of amlodipine, as compared to valsartan, revealed by ambulatory blood pressure monitoring, self blood pressure measurements and dose omission protocol.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Time Factors; Valine; Valsartan | 2004 |
Ambulatory versus clinic blood pressure for the assessment of anti hypertensive efficacy in clinical trials: insights from the Val-Syst Study.
Topics: Aged; Aged, 80 and over; Ambulatory Care Facilities; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Male; Patient Selection; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Comparison of antihypertensive effects of an angiotensin-converting enzyme inhibitor, a calcium antagonist and a diuretic in patients with hypertension not controlled by angiotensin receptor blocker monotherapy.
Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chlorthalidone; Cross-Over Studies; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
24-hour ambulatory blood-pressure effects of valsartan and hydrochlorothiazide combinations compared with amlodipine in hypertensive patients at increased cardiovascular risk: a VAST sub-study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Efficacy and tolerability of combination therapy with valsartan plus hydrochlorothiazide compared with amlodipine monotherapy in hypertensive patients with other cardiovascular risk factors: the VAST study.
Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Myocardial Infarction; Obesity; Risk Factors; Tetrazoles; Valine; Valsartan | 2005 |
A noninferiority comparison of valsartan/hydrochlorothiazide combination versus amlodipine in black hypertensives.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Black People; Blood Pressure; Calcium Channel Blockers; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Haemodynamic effects of AT1 inhibition and Ca2+-channel blockade in hypertensive patients during isometric stress.
Topics: Amlodipine; Analysis of Variance; Antihypertensive Agents; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Female; Forearm; Hand Strength; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Plethysmography; Tetrazoles; Valine; Valsartan; Vascular Resistance | 2006 |
Effects of valsartan compared to amlodipine on preventing type 2 diabetes in high-risk hypertensive patients: the VALUE trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Risk Factors; Tetrazoles; Valine; Valsartan | 2006 |
Randomized, double-blind, crossover comparison of amlodipine and valsartan in african-americans with hypertension using 24-hour ambulatory blood pressure monitoring.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Black or African American; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypertension; Male; Tetrazoles; Valine; Valsartan | 2006 |
Effects of amlodipine and valsartan on vascular damage and ambulatory blood pressure in untreated hypertensive patients.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carotid Arteries; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Pulse; Tetrazoles; Valine; Valsartan; Vascular Resistance | 2006 |
The Valsartan Antihypertensive Long-Term Use Evaluation (VALUE) trial: outcomes in patients receiving monotherapy.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Output, Low; Diabetes Mellitus; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Incidence; Male; Middle Aged; Risk; Tetrazoles; Valine; Valsartan | 2006 |
Targeting hypertension with valsartan: Lessons learned from the Valsartan/HCTZ versus Amlodipine in stage II hypertensive patients (VASt) trial.
Topics: Amlodipine; C-Reactive Protein; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Interleukin-6; Lipoproteins, LDL; Tetrazoles; Tissue Plasminogen Activator; Valine; Valsartan | 2006 |
Outcomes in subgroups of hypertensive patients treated with regimens based on valsartan and amlodipine: An analysis of findings from the VALUE trial.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Female; Heart Arrest; Heart Failure; Humans; Hypertension; Male; Middle Aged; Proportional Hazards Models; Sex Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2006 |
Effects of amlodipine and valsartan on oxidative stress and plasma methylarginines in end-stage renal disease patients on hemodialysis.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Arginine; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Female; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Methylation; Middle Aged; Oxidative Stress; Renal Dialysis; Tetrazoles; Valine; Valsartan | 2006 |
Effect of valsartan addition to amlodipine on ankle oedema and subcutaneous tissue pressure in hypertensive patients.
Topics: Adult; Age Factors; Aged; Amlodipine; Ankle; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Edema; Female; Humans; Hypertension; Male; Middle Aged; Placebos; Prospective Studies; Single-Blind Method; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Ambulatory blood pressure monitoring after 1 year on valsartan or amlodipine-based treatment: a VALUE substudy.
Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Denmark; Female; Heart Rate; Humans; Hypertension; Italy; Male; Middle Aged; Office Visits; Randomized Controlled Trials as Topic; Reproducibility of Results; Research; Risk Factors; Tetrazoles; United States; Valine; Valsartan | 2007 |
Effects of valsartan or amlodipine alone or in combination on plasma catecholamine levels at rest and during standing in hypertensive patients.
Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Catecholamines; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Posture; Rest; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Reduction of microalbuminuria in patients with type 2 diabetes: the Shiga Microalbuminuria Reduction Trial (SMART).
Topics: Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Japan; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome.
Topics: Adiponectin; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Doxazosin; Female; Humans; Hypertension; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Metoprolol; Middle Aged; Predictive Value of Tests; Prospective Studies; Ramipril; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2007 |
Tolerability and blood pressure-lowering efficacy of the combination of amlodipine plus valsartan compared with lisinopril plus hydrochlorothiazide in adult patients with stage 2 hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2007 |
Amlodipine and valsartan combined and as monotherapy in stage 2, elderly, and black hypertensive patients: subgroup analyses of 2 randomized, placebo-controlled studies.
Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Black People; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Research Design; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Two multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in combination and as monotherapy in adult patients with mild to moderate essential hyperten
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Headache; Humans; Hypertension; Male; Middle Aged; Nasopharyngitis; Tetrazoles; Valine; Valsartan | 2007 |
Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects.
Topics: Adamantane; Administration, Oral; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Area Under Curve; Cross-Over Studies; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Female; Half-Life; Headache; Humans; Male; Middle Aged; Nausea; Nitriles; Pyrrolidines; Ramipril; Tablets; Tetrazoles; Valine; Valsartan; Vildagliptin | 2008 |
Reduced incidence of new-onset atrial fibrillation with angiotensin II receptor blockade: the VALUE trial.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atrial Fibrillation; Drug Therapy, Combination; Female; Humans; Hypertension; Incidence; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Efficacy of the combination of amlodipine and valsartan in patients with hypertension uncontrolled with previous monotherapy: the Exforge in Failure after Single Therapy (EX-FAST) study.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Retreatment; Tetrazoles; Valine; Valsartan | 2008 |
Comparative evaluation of effect of valsartan/amlodipine and atenolol/amlodipine combinations on atrial fibrillation recurrence in hypertensive patients with type 2 diabetes mellitus.
Topics: Aged; Amlodipine; Anti-Arrhythmia Agents; Antihypertensive Agents; Atenolol; Atrial Fibrillation; Blood Pressure; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hypertension; Male; Middle Aged; Propafenone; Prospective Studies; Secondary Prevention; Tetrazoles; Valine; Valsartan | 2008 |
Valsartan Amlodipine Randomized Trial (VART): design, methods, and preliminary results.
Topics: 3-Iodobenzylguanidine; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Data Interpretation, Statistical; Endpoint Determination; Female; Follow-Up Studies; Humans; Hypertension; Informed Consent; Male; Middle Aged; Patient Selection; Prospective Studies; Radionuclide Imaging; Radiopharmaceuticals; Research Design; Risk Factors; Sample Size; Tetrazoles; Ultrasonography; Valine; Valsartan | 2008 |
Effects of valsartan or amlodipine on endothelial function and oxidative stress after one year follow-up in patients with essential hypertension.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Asian People; Biomarkers; Blood Pressure; Brachial Artery; Calcium Channel Blockers; Deoxyguanosine; Dinoprost; Endothelium, Vascular; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Regional Blood Flow; Tetrazoles; Valine; Valsartan; Vasodilation | 2008 |
Valsartan improves arterial stiffness in type 2 diabetes independently of blood pressure lowering.
Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Effective and safe reduction of blood pressure with the combination of amlodipine 5 mg and valsartan 160 mg in hypertensive patients not controlled by calcium channel blocker monotherapy.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2008 |
Predictors of new-onset diabetes mellitus in hypertensive patients: the VALUE trial.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Calcium Channel Blockers; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypertension; Incidence; Middle Aged; Prognosis; Prospective Studies; Risk Factors; Tetrazoles; Time Factors; Valine; Valsartan | 2008 |
Effect of valsartan and ramipril on atrial fibrillation recurrence and P-wave dispersion in hypertensive patients with recurrent symptomatic lone atrial fibrillation.
Topics: Aged; Amlodipine; Antihypertensive Agents; Atrial Fibrillation; Double-Blind Method; Electrocardiography; Female; Humans; Male; Peptide Fragments; Procollagen; Ramipril; Recurrence; Tetrazoles; Valine; Valsartan | 2008 |
Progressive effects of valsartan compared with amlodipine in prevention of diabetes according to categories of diabetogenic risk in hypertensive patients: the VALUE trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Follow-Up Studies; Humans; Hypertension; Middle Aged; Multivariate Analysis; Regression Analysis; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Impact of renin-angiotensin system inhibition on microalbuminuria in type 2 diabetes: a post hoc analysis of the Shiga Microalbuminuria Reduction Trial (SMART).
Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Creatinine; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2008 |
Effect of valsartan addition to amlodipine on insulin sensitivity in overweight-obese hypertensive patients.
Topics: Adult; Aged; Amlodipine; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Insulin; Male; Middle Aged; Obesity; Overweight; Prospective Studies; Tetrazoles; Valine; Valsartan | 2008 |
[Economics of nephroprotection in arterial hypertension and type 2 diabetes mellitus].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Drug Costs; Humans; Hypertension; Irbesartan; Kidney Diseases; Tetrazoles; Valine; Valsartan | 2008 |
Efficacy and tolerability of amlodipine/valsartan combination therapy in hypertensive patients not adequately controlled on valsartan monotherapy.
Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Single-Blind Method; Tetrazoles; Valine; Valsartan | 2009 |
Efficacy and safety of the single pill combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not controlled by amlodipine 10 mg plus olmesartan 20 mg in free combination.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Cohort Studies; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Patient Compliance; Prospective Studies; Tetrazoles; Valine; Valsartan | 2009 |
The combination of amlodipine/valsartan 5/160 mg produces less peripheral oedema than amlodipine 10 mg in hypertensive patients not adequately controlled with amlodipine 5 mg.
Topics: Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Edema; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Combination of amlodipine 10 mg and valsartan 160 mg lowers blood pressure in patients with hypertension not controlled by an ACE inhibitor/CCB combination.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Resistance; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Long-term tolerability and efficacy of the combination of amlodipine/valsartan in hypertensive patients: a 54-week, open-label extension study.
Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Placebos; Tetrazoles; Valine; Valsartan | 2009 |
Add-on benefits of amlodipine and thiazide in nondiabetic chronic kidney disease stage 1/2 patients treated with valsartan.
Topics: Adult; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Carotid Arteries; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Renal Insufficiency, Chronic; Tetrazoles; Thiazides; Valine; Valsartan | 2009 |
Effects of force-titrated valsartan/hydrochlorothiazide versus amlodipine/hydrochlorothiazide on ambulatory blood pressure in patients with stage 2 hypertension: the EVALUATE study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Triple antihypertensive therapy with amlodipine, valsartan, and hydrochlorothiazide: a randomized clinical trial.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Single-Blind Method; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Efficacy and tolerability of amlodipine/valsartan combination therapy in hypertensive patients not adequately controlled on amlodipine monotherapy.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Placebos; Tetrazoles; Treatment Failure; Treatment Outcome; Valine; Valsartan | 2009 |
Randomized study to compare valsartan +/- HCTZ versus amlodipine +/- HCTZ strategies to maximize blood pressure control.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; South America; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2009 |
Amlodipine/valsartan/hydrochlorothiazide triple combination therapy in moderate/severe hypertension: Secondary analyses evaluating efficacy and safety.
Topics: Adolescent; Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Tetrazoles; Valine; Valsartan | 2009 |
[Efficacy and safety of the single pill combination of valsartan 80 mg plus amlodipine 5 mg in mild to moderate essential hypertensive patients without adequate blood pressure control by monotherapy].
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2009 |
Effect of valsartan or olmesartan addition to amlodipine on ankle edema in hypertensive patients.
Topics: Adult; Aged; Amlodipine; Ankle Joint; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Edema; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Norepinephrine; Prospective Studies; Tetrazoles; Valine; Valsartan | 2010 |
Valsartan addition to amlodipine is more effective than losartan addition in hypertensive patients inadequately controlled by amlodipine.
Topics: Adult; Aged; Amlodipine; Anthracenes; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2010 |
Amlodipine-valsartan combination decreases central systolic blood pressure more effectively than the amlodipine-atenolol combination: the EXPLOR study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Probability; Prospective Studies; Severity of Illness Index; Single-Blind Method; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2010 |
Rationale and design of the NAGOYA HEART Study: comparison between valsartan and amlodipine regarding morbidity and mortality in patients with hypertension and glucose intolerance.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Complications; Humans; Hypertension; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2010 |
Combined therapy with renin-angiotensin system and calcium channel blockers in type 2 diabetic hypertensive patients with proteinuria: effects on soluble TWEAK, PTX3, and flow-mediated dilation.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; C-Reactive Protein; Calcium Channel Blockers; Chi-Square Distribution; Cytokine TWEAK; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System; Serum Amyloid P-Component; Tetrazoles; Time Factors; Treatment Outcome; Tumor Necrosis Factors; Turkey; Valine; Valsartan; Vasodilation | 2010 |
Efficacy and safety of a single-pill combination of amlodipine/valsartan in Asian hypertensive patients inadequately controlled with amlodipine monotherapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Amlodipine; Antihypertensive Agents; Asian People; Double-Blind Method; Drug Combinations; Drug Resistance; Female; Humans; Hypertension; Male; Middle Aged; Tablets; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2010 |
Angiotensin receptor blocker/diuretic combination preserves insulin responses in obese hypertensives.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Glucose; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Insulin; Male; Middle Aged; Obesity; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Chronotherapy with valsartan/amlodipine fixed combination: improved blood pressure control of essential hypertension with bedtime dosing.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Drug Chronotherapy; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Sleep; Tetrazoles; Valine; Valsartan | 2010 |
Time to achieve blood pressure goal with a combination versus a conventional monotherapy approach in hypertensive patients with metabolic syndrome.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Comorbidity; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Metabolic Syndrome; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2010 |
Angiotensin II receptor blockade with valsartan decreases plasma osteopontin levels in patients with essential hypertension.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; C-Reactive Protein; Female; Humans; Hypertension; Male; Middle Aged; Osteopontin; Tetrazoles; Valine; Valsartan | 2011 |
Evaluation of pharmacokinetic interactions between amlodipine, valsartan, and hydrochlorothiazide in patients with hypertension.
Topics: Adolescent; Adult; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Triple combination therapy with amlodipine, valsartan, and hydrochlorothiazide vs dual combination therapy with amlodipine and hydrochlorothiazide for stage 2 hypertensive patients.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Effects of valsartan and amlodipine on cardiorenal protection in Japanese hypertensive patients: the Valsartan Amlodipine Randomized Trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Blood Pressure; Cardiovascular Diseases; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Moderate versus intensive treatment of hypertension with amlodipine/valsartan for patients uncontrolled on angiotensin receptor blocker monotherapy.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Tetrazoles; Valine; Valsartan | 2011 |
24-Hour ambulatory blood pressure response to combination valsartan/hydrochlorothiazide and amlodipine/hydrochlorothiazide in stage 2 hypertension by ethnicity: the EVALUATE study.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Ethnicity; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Racial Groups; Regression Analysis; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Real-life safety and effectiveness of amlodipine/valsartan combination in the treatment of hypertension.
Topics: Administration, Oral; Amlodipine; Antihypertensive Agents; Bangladesh; Blood Pressure; Blood Pressure Monitoring, Ambulatory; China; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Egypt; Female; Heart Rate; Humans; Hypertension; Malaysia; Male; Middle Aged; Pakistan; Product Surveillance, Postmarketing; Russia; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
24-Hour ambulatory blood pressure control with triple-therapy amlodipine, valsartan and hydrochlorothiazide in patients with moderate to severe hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Beneficial cardiometabolic actions of telmisartan plus amlodipine therapy in elderly patients with poorly controlled hypertension.
Topics: Adiponectin; Age Factors; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Drug Substitution; Drug Therapy, Combination; Female; Humans; Hypertension; Japan; Male; Prospective Studies; Telmisartan; Tetrazoles; Time Factors; Treatment Outcome; Up-Regulation; Valine; Valsartan | 2011 |
Efficacy and tolerability of a single-pill combination of amlodipine/valsartan in Asian hypertensive patients not adequately controlled with valsartan monotherapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Calcium Channel Blockers; China; Double-Blind Method; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypertension; Korea; Male; Middle Aged; Tetrazoles; Thailand; Treatment Outcome; Valine; Valsartan; Young Adult | 2011 |
Rationale and design of the Newer Versus Older Antihypertensive Agents in African Hypertensive Patients (NOAAH) trial.
Topics: Adult; Africa South of the Sahara; Aged; Amlodipine; Antihypertensive Agents; Bisoprolol; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Research Design; Risk Factors; Tetrazoles; Valine; Valsartan | 2011 |
[The Shiga Microalbuminuria Reduction Trial].
Topics: Albuminuria; Amlodipine; Animals; Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Middle Aged; Prospective Studies; Rats; Tetrazoles; Valine; Valsartan | 2010 |
Combination angiotensin-receptor blocker (ARB)/calcium channel blocker with HCTZ vs the maximal recommended dose of an ARB with HCTZ in patients with stage 2 hypertension: the exforge as compared to losartan treatment in stage 2 systolic hypertension (EXA
Topics: Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; United States; Valine; Valsartan | 2011 |
[Efficacy of fixed combination amlodipine/valsartan in hospitalized patients with hypertensive disease].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Drug Monitoring; Drug Synergism; Female; Humans; Hypertension; Inpatients; Male; Medication Adherence; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Office and ambulatory blood pressure-lowering effects of combination valsartan/hydrochlorothiazide vs. hydrochlorothiazide-based therapy in obese, hypertensive patients.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Comorbidity; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Obesity; Office Visits; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2011 |
Effects of valsartan and amlodipine on home blood pressure and cardiovascular events in Japanese hypertensive patients: a subanalysis of the VART.
Topics: Aged; Albuminuria; Amlodipine; Angina Pectoris; Antihypertensive Agents; Asian People; Blood Pressure; Cardiovascular Diseases; Cause of Death; Creatinine; Death, Sudden; Female; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2012 |
Distinct effects of fixed combinations of valsartan with either amlodipine or hydrochlorothiazide on lipoprotein subfraction profile in patients with hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Cholesterol; Female; Humans; Hydrochlorothiazide; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Particle Size; Tetrazoles; Triglycerides; Valine; Valsartan | 2013 |
Comparing antihypertensive effect and plasma ciclosporin concentration between amlodipine and valsartan regimens in hypertensive renal transplant patients receiving ciclosporin therapy.
Topics: Adult; Amlodipine; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Pressure; Cyclosporine; Cytochrome P-450 CYP3A; Double-Blind Method; Drug Interactions; Female; Genotype; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prospective Studies; Tetrazoles; Valine; Valsartan | 2011 |
Ambulatory blood pressure response to triple therapy with an angiotensin-receptor blocker (ARB), calcium-channel blocker (CCB), and HCTZ versus dual therapy with an ARB and HCTZ.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Comparison between valsartan and amlodipine regarding cardiovascular morbidity and mortality in hypertensive patients with glucose intolerance: NAGOYA HEART Study.
Topics: Amlodipine; Antihypertensive Agents; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glucose Intolerance; Glycated Hemoglobin; Humans; Hypertension; Japan; Male; Middle Aged; Morbidity; Prospective Studies; Risk Factors; Survival Rate; Tetrazoles; Valine; Valsartan | 2012 |
Antihypertensive and metabolic effects of Angiotensin receptor blocker/diuretic combination therapy in obese, hypertensive African American and white patients.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Black or African American; Blood Glucose; Diuretics; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hyperglycemia; Hypertension; Insulin; Intention to Treat Analysis; Male; Middle Aged; Obesity, Abdominal; Prediabetic State; Tetrazoles; Treatment Outcome; Valine; Valsartan; White People | 2013 |
Effects of valsartan versus olmesartan addition to amlodipine/hydrochlorothiazide combination in treating stage 2 hypertensive patients.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2012 |
[Effects of valsartan combined with amlodipine or hydrochlorothiazide regimen on blood pressure variation in elderly hypertensive patients].
Topics: Aged; Amlodipine; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2012 |
Effects of valsartan or ramipril addition to amlodipine/hydrochlorothiazide combination on left ventricular mass in diabetic hypertensive patients with left ventricular hypertrophy.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Ramipril; Tetrazoles; Valine; Valsartan | 2012 |
Effects of exercise therapy alone and in combination with a calcium channel blocker or an angiotensin receptor blocker in hypertensive patients.
Topics: Adult; Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Exercise Therapy; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2012 |
Amlodipine/valsartan 5/160 mg versus valsartan 160 mg in Chinese hypertensives.
Topics: Adult; Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Asian People; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2013 |
Comparison of the efficacy and safety profiles of two fixed-dose combinations of antihypertensive agents, amlodipine/benazepril versus valsartan/hydrochlorothiazide, in patients with type 2 diabetes mellitus and hypertension: a 16-week, multicenter, rando
Topics: Aged; Albuminuria; Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Combinations; Female; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prospective Studies; Taiwan; Tetrazoles; Time Factors; Treatment Outcome; Uric Acid; Valine; Valsartan | 2012 |
Post-marketing surveillance study of valsartan/amlodipine combination in Taiwanese hypertensive patients.
Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Product Surveillance, Postmarketing; Prospective Studies; Taiwan; Tetrazoles; Time Factors; Valine; Valsartan | 2012 |
Cardiovascular outcomes in hypertensive patients: comparing single-agent therapy with combination therapy.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Prognosis; Retrospective Studies; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2012 |
Changes in aortic pulse wave velocity in hypertensive postmenopausal women: comparison between a calcium channel blocker vs angiotensin receptor blocker regimen.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Postmenopause; Pulse Wave Analysis; Tetrazoles; Valine; Valsartan; Vascular Stiffness | 2012 |
The comparative effects of valsartan and amlodipine on vascular microinflammation in newly diagnosed hypertensive patients.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Calcium Channel Blockers; Female; Humans; Hypertension; Inflammation Mediators; Male; Middle Aged; Prospective Studies; Risk Factors; Serum Amyloid P-Component; Tetrazoles; Valine; Valsartan; Vasculitis | 2013 |
An additional LDL-lowering effect of amlodipine; not only an antihypertensive?
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Cholesterol; Dyslipidemias; Essential Hypertension; Female; Humans; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Tetrazoles; Triglycerides; Valine; Valsartan | 2013 |
The comparative effects of valsartan and amlodipine on vWf levels and N/L ratio in patients with newly diagnosed hypertension.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Essential Hypertension; Female; Humans; Hypertension; Leukocyte Count; Lymphocytes; Male; Middle Aged; Neutrophils; Prospective Studies; Tetrazoles; Valine; Valsartan; von Willebrand Factor | 2013 |
Amlodipine seems to be superior to valsartan in decreasing microalbuminuria in newly diagnosed hypertensive patients: a novel effect to be explained with hyperfiltration?
Topics: Adult; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2013 |
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate.
Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan | 2013 |
Effects of CPAP on "vascular" risk factors in patients with obstructive sleep apnea and arterial hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arterial Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Continuous Positive Airway Pressure; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Manometry; Middle Aged; Polysomnography; Predictive Value of Tests; Pulse Wave Analysis; Risk Factors; Russia; Severity of Illness Index; Sleep Apnea, Obstructive; Tetrazoles; Treatment Outcome; Valine; Valsartan; Vascular Stiffness | 2013 |
Effects of demographics on the antihypertensive efficacy of triple therapy with amlodipine, valsartan, and hydrochlorothiazide for moderate to severe hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Demography; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Valine; Valsartan; Young Adult | 2013 |
Efficacy of newer versus older antihypertensive drugs in black patients living in sub-Saharan Africa.
Topics: Adult; Africa South of the Sahara; Amlodipine; Antihypertensive Agents; Bisoprolol; Black People; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Pharmacokinetic comparison of 2 fixed-dose combination tablets of amlodipine and valsartan in healthy male Korean volunteers: a randomized, open-label, 2-period, single-dose, crossover study.
Topics: Administration, Oral; Adult; Amlodipine; Asian People; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Healthy Volunteers; Humans; Male; Middle Aged; Tablets; Tetrazoles; Valine; Valsartan; Young Adult | 2013 |
Efficacy and safety of valsartan and amlodipine single-pill combination in hypertensive patients (PEAK study).
Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Patient Compliance; Tetrazoles; Treatment Outcome; Turkey; Valine; Valsartan | 2013 |
Effect of renin-angiotensin system blockade on soluble Klotho in patients with type 2 diabetes, systolic hypertension, and albuminuria.
Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diuretics; Female; Glucuronidase; Hospitals, University; Humans; Hydrochlorothiazide; Hypertension; Klotho Proteins; London; Male; Middle Aged; Phosphates; Pulse Wave Analysis; Renin-Angiotensin System; Systole; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2013 |
Effects of valsartan versus amlodipine in diabetic hypertensive patients with or without previous cardiovascular disease.
Topics: Aged; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Case-Control Studies; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Female; Heart Failure; Hospitalization; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Proportional Hazards Models; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Comparative effects of telmisartan and valsartan as add-on agents for hypertensive patients with morning blood pressure insufficiently controlled by amlodipine monotherapy.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Chemical Analysis; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Endpoint Determination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Sleep; Telmisartan; Tetrazoles; Valine; Valsartan | 2014 |
[The influence of citoflavin on molecular mechanisms of hypertensive encephalopathy development in patients with systolic arterial hypertension].
Topics: Aged; Aged, 80 and over; Amlodipine; Aspirin; Atorvastatin; Blood Pressure; Blood Proteins; Drug Combinations; Drug Therapy, Combination; Echocardiography; Female; Flavin Mononucleotide; Hemodynamics; Heptanoic Acids; Humans; Hypertension; Hypertensive Encephalopathy; Inosine Diphosphate; Male; Neuroprotective Agents; Niacinamide; Pyrroles; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Succinates; Systole; Tetrazoles; Valine; Valsartan | 2014 |
[Optimization of arterial hypertension management by the use of two- and three-drugs fixed dose combinations at the daily stay department].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Day Care, Medical; Dose-Response Relationship, Drug; Drug Combinations; Drug Monitoring; Drug Synergism; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2014 |
Aortic remodelling following the treatment and regression of hypertensive left ventricular hypertrophy: a cardiovascular magnetic resonance study.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Aorta, Thoracic; Bendroflumethiazide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Essential Hypertension; Female; Follow-Up Studies; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Sympatholytics; Treatment Outcome; Valsartan; Vascular Remodeling; Vascular Stiffness | 2015 |
Evening versus morning dosing of antihypertensive drugs in hypertensive patients with sleep apnoea: a cross-over study.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Continuous Positive Airway Pressure; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Sleep Apnea, Obstructive; Valsartan | 2015 |
Comparison of single-pill strategies first line in hypertension: perindopril/amlodipine versus valsartan/amlodipine.
Topics: Adult; Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Perindopril; Valsartan | 2015 |
Endocan, a novel marker of endothelial dysfunction in patients with essential hypertension: comparative effects of amlodipine and valsartan.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Endothelium, Vascular; Essential Hypertension; Female; Humans; Hypertension; Male; Middle Aged; Neoplasm Proteins; Proteoglycans; Tetrazoles; Valine; Valsartan | 2015 |
Assessment of glomerular filtration rate based on alterations of serum brain-derived neurotrophic factor in type 2 diabetic subjects treated with amlodipine/benazepril or valsartan/hydrochlorothiazide.
Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Male; Middle Aged; Valsartan | 2015 |
Choice of Antihypertensive Combination Therapy Based on Daily Salt Intake.
Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metabolic Syndrome; Middle Aged; Potassium; Prospective Studies; Sodium; Sodium Chloride, Dietary; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2015 |
Efficacy and safety of two single-pill fixed-dose combinations of angiotensin II receptor blockers/calcium channel blockers in hypertensive patients (EXAMINER study).
Topics: Aged; Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Drug Monitoring; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Tetrazoles; Treatment Outcome; Triglycerides; Uric Acid; Valsartan | 2016 |
No evidence for a J-shaped curve in treated hypertensive patients with increased cardiovascular risk: The VALUE trial.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Coronary Artery Disease; Diastole; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Systole; Treatment Outcome; Valsartan | 2016 |
Predictors of cardiac morbidity in diabetic, new-onset diabetic and non-diabetic high-risk hypertensive patients: The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Complications; Female; Heart Failure; Hospitalization; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Risk Factors; Valsartan | 2016 |
The Effects of Valsartan and Amlodipine on the Levels of Irisin, Adropin, and Perilipin.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Proteins; Calcium; Carrier Proteins; Female; Fibronectins; Humans; Hypertension; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Obesity; Peptides; Perilipin-1; Phosphoproteins; Valsartan | 2015 |
Pharmacokinetic drug-drug interaction assessment between LCZ696, an angiotensin receptor neprilysin inhibitor, and hydrochlorothiazide, amlodipine, or carvedilol.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Area Under Curve; Arizona; Biphenyl Compounds; Calcium Channel Blockers; Carbazoles; Carvedilol; Cross-Over Studies; Diuretics; Drug Administration Schedule; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Hydrochlorothiazide; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Neprilysin; Propanolamines; Protease Inhibitors; Tetrazoles; Valsartan | 2015 |
Efficacy and safety of sacubitril/valsartan (LCZ696) add-on to amlodipine in Asian patients with systolic hypertension uncontrolled with amlodipine monotherapy.
Topics: Aged; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Asian People; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Systole; Tetrazoles; Treatment Outcome; Valsartan | 2017 |
Effects of Amlodipine and Valsartan on Blood Pressure Variability and Pulse Wave Velocity in Hypertensive Patients.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypertension; Male; Middle Aged; Pulse Wave Analysis; Valsartan | 2017 |
Effects of valsartan and amlodipine on oxidative stress in type 2 diabetic patients with hypertension: a randomized, multicenter study.
Topics: Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Valsartan | 2017 |
Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and Hypertension.
Topics: Adipose Tissue; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Combinations; Drug Monitoring; Exercise; Female; Humans; Hypertension; Lipid Metabolism; Male; Middle Aged; Natriuretic Peptides; Neprilysin; Obesity, Abdominal; Tetrazoles; Treatment Outcome; Valsartan | 2018 |
The effects of angiotensin receptor neprilysin inhibition by sacubitril/valsartan on adipose tissue transcriptome and protein expression in obese hypertensive patients.
Topics: Adipose Tissue; Adult; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Biphenyl Compounds; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Neprilysin; Obesity; Proteins; Subcutaneous Fat; Tetrazoles; Transcriptome; Valsartan | 2018 |
Pharmacokinetic Drug Interactions Between Amlodipine, Valsartan, and Rosuvastatin in Healthy Volunteers.
Topics: Adult; Amlodipine; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Healthy Volunteers; Humans; Hypertension; Male; Middle Aged; Rosuvastatin Calcium; Valsartan | 2019 |
Efficacy of a new single-pill combination of a thiazide-like diuretic and a calcium channel blocker (indapamide sustained release/amlodipine) in essential hypertension.
Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Delayed-Action Preparations; Diuretics; Double-Blind Method; Drug Combinations; Essential Hypertension; Female; Humans; Indapamide; Male; Middle Aged; Thiazides; Valsartan | 2019 |
Pharmacokinetic and Safety Profiles of a Fixed-Dose Combination of Amlodipine, Valsartan, and Atorvastatin: A 3-Period Replicate Crossover Study.
Topics: Adult; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Area Under Curve; Atorvastatin; Cross-Over Studies; Drug Combinations; Humans; Male; Therapeutic Equivalency; Valsartan; Young Adult | 2020 |
Circulating microparticles and central blood pressure according to antihypertensive strategy.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Cell-Derived Microparticles; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Rosuvastatin Calcium; Valsartan | 2019 |
Genetic factors associated with elevation of uric acid after treatment with thiazide-like diuretic in patients with essential hypertension.
Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Essential Hypertension; Female; Genome-Wide Association Study; Humans; Indapamide; Male; Middle Aged; Polymorphism, Single Nucleotide; Uric Acid; Valsartan | 2020 |
Blood Pressure-Lowering Profiles and Clinical Effects of Angiotensin Receptor Blockers Versus Calcium Channel Blockers.
Topics: Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Determination; Calcium Channel Blockers; Female; Heart Failure; Humans; Hypotension; Male; Middle Aged; Myocardial Infarction; Outcome and Process Assessment, Health Care; Risk Assessment; Stroke; Time; Valsartan | 2020 |
Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines Levels in Hypertensive Patients: Speckle Tracking Echocardiography.
Topics: Adipokines; Adiponectin; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; C-Reactive Protein; Calcium Channel Blockers; Echocardiography; Egypt; Female; Humans; Hypertension; Leptin; Male; Middle Aged; Predictive Value of Tests; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Valsartan; Ventricular Function, Left; Ventricular Remodeling | 2020 |
Amlodipine/valsartan fixed-dose combination treatment in the management of hypertension: A double-blind, randomized trial.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Valsartan | 2020 |
Effects of the valsartan/amlodipine combination and nifedipine gastrointestinal therapeutic system monotherapy on brachial pulse pressure and radial augmentation index in hypertensive patients.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nifedipine; Tetrazoles; Treatment Outcome; Valsartan | 2021 |
Efficacy and safety of Tengfu Jiangya tablet combined with valsartan/amlodipine in the treatment of stage 2 hypertension: study protocol for a randomized controlled trial.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Tablets; Valsartan | 2022 |
114 other study(ies) available for valsartan and amlodipine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Disparate effects of angiotensin II antagonists and calcium channel blockers on albuminuria in experimental diabetes and hypertension: potential role of nephrin.
Topics: Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Drug Therapy, Combination; Hypertension; Kidney Glomerulus; Male; Membrane Proteins; Proteins; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sclerosis; Systole; Tetrazoles; Valine; Valsartan; Verapamil | 2003 |
The role of nitric oxide in the regulation of glomerular haemodynamics in humans.
Topics: Adult; Amlodipine; Angiotensin Receptor Antagonists; Calcium Channel Blockers; Glomerular Filtration Rate; Hemodynamics; Humans; Kidney Glomerulus; Middle Aged; Nitric Oxide; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2004 |
Valsartan treatment of hypertension--does VALUE add value?
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Endpoint Determination; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan | 2004 |
Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
Effects of the angiotensin-1 receptor blocker valsartan compared with amlodipine on renal hemodynamics.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Glomerular Filtration Rate; Humans; Hypertension; Microcirculation; Receptor, Angiotensin, Type 1; Renal Circulation; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2004 |
[The value of VALUE--a hypertension study which compared valsartan with amlodipine. New data support early, optimal blood pressure control for high-risk patients].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Risk Factors; Tetrazoles; Valine; Valsartan | 2004 |
[Preventing end-organ damage in hypertension. What is the significance of the VALUE Study for general practice?].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Cardiovascular Diseases; Cause of Death; Humans; Hypertension; Myocardial Infarction; Randomized Controlled Trials as Topic; Survival Rate; Tetrazoles; Valine; Valsartan | 2004 |
[Type 2 diabetic patient with kidney damage. Sartans banish dialysis risk].
Topics: Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Kidney Failure, Chronic; Randomized Controlled Trials as Topic; Renal Dialysis; Tetrazoles; Valine; Valsartan | 2004 |
VALUE in hypertension treatment.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2004 |
[AT1 blocker or calcium antagonist in treatment of hypertension. What protects the heart better?].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Hypertension; Risk Factors; Tetrazoles; Valine; Valsartan | 2004 |
[VALUE study underscores the significance of reaching aimed blood pressure values for minimizing cardiovascular risks].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Sodium Chloride Symporter Inhibitors; Tetrazoles; Time Factors; Valine; Valsartan | 2004 |
[VALUE study underscores the importance of reaching goal blood pressure values for minimization of cardiovascular risks].
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Prospective Studies; Randomized Controlled Trials as Topic; Reference Values; Risk Factors; Tetrazoles; Time Factors; Valine; Valsartan | 2004 |
Angiotensin receptor blockers and myocardial infarction.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Myocardial Infarction; Tetrazoles; Truth Disclosure; Valine; Valsartan | 2004 |
Valuable lessons from VALUE.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hypertension; Tetrazoles; Valine; Valsartan | 2004 |
The value of VALUE: the importance of lowering blood pressure quickly.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Middle Aged; Risk Factors; Tetrazoles; Valine; Valsartan | 2004 |
Is there more to life than blood pressure?
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
In search of true value.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2005 |
Angiotensin II type 2 receptor expression after vascular injury: differing effects of angiotensin-converting enzyme inhibition and angiotensin receptor blockade.
Topics: Amlodipine; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Blood Pressure; Carotid Artery, Common; Cyclic GMP; Male; Rats; Rats, Inbred BN; Receptor, Angiotensin, Type 2; Tetrazoles; Tunica Intima; Tunica Media; Valine; Valsartan | 2006 |
Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers.
Topics: Adolescent; Adult; Amides; Amlodipine; Antihypertensive Agents; Drug Interactions; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan | 2006 |
Retinopathy and choroidopathy as the initial signs of hypertensive brainstem encephalopathy.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Brain Stem; Choroid Diseases; Drug Therapy, Combination; Female; Fluorescein Angiography; Humans; Hypertensive Encephalopathy; Magnetic Resonance Imaging; Metoprolol; Middle Aged; Retinal Diseases; Tetrazoles; Valine; Valsartan | 2006 |
Added VALUE of an ancillary study on ambulatory blood pressure monitoring.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Heart Rate; Humans; Hypertrophy, Left Ventricular; Randomized Controlled Trials as Topic; Reproducibility of Results; Research; Sample Size; Tetrazoles; Valine; Valsartan | 2007 |
Risk of diabetes in a real-world setting among patients initiating antihypertensive therapy with valsartan or amlodipine.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Databases, Factual; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Risk Assessment; Risk Factors; Risk Reduction Behavior; Tetrazoles; Time Factors; Treatment Outcome; United States; Valine; Valsartan | 2007 |
Angiotensin II receptor blockers downsize adipocytes in spontaneously type 2 diabetic rats with visceral fat obesity.
Topics: Adipocytes; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Calcium Channel Blockers; Cell Size; Diabetes Mellitus, Type 2; Disease Models, Animal; Insulin; Intra-Abdominal Fat; Male; Obesity; PPAR gamma; Random Allocation; Rats; Rats, Long-Evans; Telmisartan; Tetrazoles; Valine; Valsartan | 2007 |
Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure.
Topics: Acetophenones; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Apoptosis; Biopterins; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Endothelium, Vascular; Heart Failure, Diastolic; Hydralazine; Hypertension; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium Chloride, Dietary; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan; Vasodilation | 2007 |
[Risk oriented therapy of hypertension. Lowering blood pressure and risk].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diabetic Nephropathies; Humans; Hypertension; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan | 2007 |
Two amlodipine/ARB combinations for hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Humans; Hypertension; Imidazoles; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2007 |
Decreased expression of angiotensin II type 1 and type 2 receptors in the brain after long-term administration of antihypertensive drugs in stroke-prone spontaneously hypertensive rat.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Brain Stem; Calcium Channel Blockers; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Enalapril; Hypertension; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Stroke; Tetrazoles; Time Factors; Valine; Valsartan | 2008 |
Prolonged severe hypotension following combined amlodipine and valsartan ingestion.
Topics: Aged; Amlodipine; Antidotes; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Cardiac Catheterization; Drug Interactions; Drug Overdose; Female; Glucagon; Humans; Hypotension; Insulin; Naloxone; Severity of Illness Index; Suicide, Attempted; Tetrazoles; Time Factors; Valine; Valsartan | 2008 |
Application in the STRATHE trial of a score system to compare the efficacy and the tolerability of different therapeutic strategies in the management of hypertension.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Double-Blind Method; Drug Therapy, Combination; France; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Losartan; Perindopril; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Adherence with multiple-combination antihypertensive pharmacotherapies in a US managed care database.
Topics: Adolescent; Adult; Age Factors; Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Insurance Claim Review; Male; Managed Care Programs; Middle Aged; Patient Compliance; Tetrazoles; United States; Valine; Valsartan | 2008 |
Cost-effectiveness analysis: controlled-release nifedipine and valsartan combination therapy in patients with essential hypertension: the adalat CR and valsartan cost-effectiveness combination (ADVANCE-Combi) study.
Topics: Amlodipine; Cost-Benefit Analysis; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Japan; Nifedipine; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan | 2008 |
Effectiveness of add-on therapy with amlodipine in hypertensive patients receiving valsartan.
Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cohort Studies; Databases, Factual; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult | 2008 |
Development and validation of a highly sensitive and robust LC-ESI-MS/MS method for simultaneous quantitation of simvastatin acid, amlodipine and valsartan in human plasma: application to a clinical pharmacokinetic study.
Topics: Acetonitriles; Amlodipine; Antihypertensive Agents; Chromatography, High Pressure Liquid; Humans; Male; Reproducibility of Results; Sensitivity and Specificity; Simvastatin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tetrazoles; Time Factors; Valine; Valsartan | 2009 |
Triple fixed-dose combination therapy: back to the past.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2009 |
Exforge HCT.
Topics: Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Drug Combinations; Drug Costs; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2009 |
Re: Efficacy and safety of the single pill combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not controlled by amlodipine 10 mg plus olmesartan 20 mg in free combination.
Topics: Amlodipine; Antihypertensive Agents; Clinical Trials as Topic; Dosage Forms; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Tablets; Tetrazoles; Treatment Failure; Treatment Outcome; Valine; Valsartan | 2009 |
Amlodipine/valsartan/hydrochlorothiazide: fixed-dose combination in hypertension.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials, Phase III as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2009 |
[Intermedin (IMD) gene expression in hypertrophic cardiac myocyte of renal vascular hypertension rats and the intervention of Valsartan, Amlodipine and Enalapril in the expression].
Topics: Adrenomedullin; Amlodipine; Animals; Antihypertensive Agents; Cardiomegaly; Enalapril; Hypertension, Renovascular; Male; Myocardium; Neuropeptides; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Valine; Valsartan | 2009 |
Role of valsartan, amlodipine and hydrochlorothiazide fixed combination in blood pressure control: an update.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan | 2010 |
Comparison of amlodipine/valsartan fixed-dose combination therapy and conventional therapy.
Topics: Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Female; Health Services; Humans; Hypertension; Male; Medical Audit; Middle Aged; Outcome Assessment, Health Care; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2010 |
Simultaneous spectrofluorimetric determination of amlodipine besylate and valsartan in their combined tablets.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Drug Combinations; Limit of Detection; Spectrophotometry; Tablets; Tetrazoles; Valine; Valsartan | 2010 |
The N-type and L-type calcium channel blocker cilnidipine suppresses renal injury in Dahl rats fed a high-salt diet.
Topics: Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Disease Models, Animal; Drug Therapy, Combination; Glomerulonephritis; Hypertension; Kidney; Kidney Diseases; Male; Organ Size; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tetrazoles; Time Factors; Valine; Valsartan | 2010 |
Effects of an N-type calcium antagonist on angiotensin II-renin feedback.
Topics: Amlodipine; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Dihydropyridines; Dose-Response Relationship, Drug; Male; Models, Biological; Rats; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2011 |
Amlodipine + valsartan + hydrochlorothiazide. A 3-drug fixed-dose combination for hypertension: too many drawbacks.
Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Packaging; Humans; Hydrochlorothiazide; Hypertension; Medication Errors; Tetrazoles; Valine; Valsartan | 2011 |
Comparison of real-world adherence, healthcare resource utilization and costs for newly initiated valsartan/amlodipine single-pill combination versus angiotensin receptor blocker/calcium channel blocker free-combination therapy.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Female; Health Care Costs; Health Services; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Retrospective Studies; Tetrazoles; United States; Valine; Valsartan | 2011 |
Beneficial effects of combination of valsartan and amlodipine on salt-induced brain injury in hypertensive rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain; Calcium Channel Blockers; Calcium Channels; Carotid Arteries; Drug Therapy, Combination; Endothelial Cells; Hypertension; Hypoxia-Ischemia, Brain; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Random Allocation; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sodium Chloride, Dietary; Tetrazoles; Tyrosine; Valine; Valsartan | 2011 |
Simple RP-HPLC method for determination of triple drug combination of valsartan, amlodipine and hydrochlorothiazide in human plasma.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Diuretics; Drug Therapy, Combination; Guideline Adherence; Guidelines as Topic; Humans; Hydrochlorothiazide; Reproducibility of Results; Tetrazoles; Valine; Valsartan; Vasodilator Agents | 2012 |
A comparison of the effects of fixed dose vs. single-agent combinations on 24-h blood pressure variability.
Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Time Factors; Valine; Valsartan | 2012 |
Additive effects of cilnidipine and angiotensin II receptor blocker in preventing the progression of diabetic nephropathy in diabetic spontaneously hypertensive rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dihydropyridines; Disease Progression; Drug Therapy, Combination; Glomerulonephritis; Glucagon; Glucose Transporter Type 1; Glycated Hemoglobin; Glycogen; Hypertension; Kidney; Male; Norepinephrine; Proteinuria; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan | 2013 |
Improving drug adherence using fixed combinations caused beneficial treatment outcomes and decreased health-care costs in patients with hypertension.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Health Care Costs; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Prospective Studies; Retrospective Studies; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2013 |
Exfoliative esophagitis in a patient with metastatic renal cell carcinoma during sunitinib treatment.
Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Aspirin; Carcinoma, Renal Cell; Cyclooxygenase 2 Inhibitors; Esophagitis; Humans; Hypertension; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Nephrectomy; Pyrroles; Sunitinib; Tetrazoles; Valine; Valsartan | 2013 |
Concurrent estimation of amlodipine besylate, hydrochlorothiazide and valsartan by RP-HPLC, HPTLC and UV-spectrophotometry.
Topics: Amlodipine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Combinations; Hydrochlorothiazide; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets; Tetrazoles; Valine; Valsartan | 2014 |
Pill burden in hypertensive patients treated with single-pill combination therapy--an observational study.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Cost of Illness; Drug Combinations; Drug Therapy, Combination; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2013 |
Amlodipine increases vitamin D levels more than valsartan in newly diagnosed hypertensive patients: pointing to an additional effect on bone metabolism or a novel marker of inflammation?
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Biomarkers; Bone Remodeling; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan; Vitamin D | 2013 |
Comparative study between derivative spectrophotometry and multivariate calibration as analytical tools applied for the simultaneous quantitation of Amlodipine, Valsartan and Hydrochlorothiazide.
Topics: Amlodipine; Calibration; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Least-Squares Analysis; Multivariate Analysis; Reproducibility of Results; Spectrophotometry; Spectrophotometry, Ultraviolet; Tablets; Tetrazoles; Valine; Valsartan | 2013 |
Different approaches in Partial Least Squares and Artificial Neural Network models applied for the analysis of a ternary mixture of Amlodipine, Valsartan and Hydrochlorothiazide.
Topics: Amlodipine; Antihypertensive Agents; Dosage Forms; Hydrochlorothiazide; Least-Squares Analysis; Neural Networks, Computer; Principal Component Analysis; Spectrophotometry, Ultraviolet; Tetrazoles; Valine; Valsartan | 2014 |
Efficacy and safety of valsartan/amlodipine single-pill combination in patients with essential hypertension (PEAK LOW).
Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Turkey; Valine; Valsartan | 2014 |
Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology.
Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Azetidinecarboxylic Acid; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Combinations; Drug Costs; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Nephrology; Patient Satisfaction; Practice Patterns, Physicians'; Renal Insufficiency, Chronic; Retrospective Studies; Surveys and Questionnaires; Telmisartan; Tetrazoles; Valsartan | 2015 |
Comparative effects of valsartan in combination with cilnidipine or amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Dihydropyridines; Drug Evaluation, Preclinical; Drug Therapy, Combination; Heart; Hypertension; Hypertrophy, Left Ventricular; Male; Myocytes, Cardiac; Oxidative Stress; Rats, Inbred Dahl; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Ventricular Remodeling | 2015 |
Novel spectrophotometric methods for simultaneous determination of Amlodipine, Valsartan and Hydrochlorothiazide in their ternary mixture.
Topics: Amlodipine; Antihypertensive Agents; Hydrochlorothiazide; Limit of Detection; Spectrophotometry; Tetrazoles; Valine; Valsartan | 2015 |
Real-world effectiveness of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide in high-risk patients and other subgroups.
Topics: Administration, Oral; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asia; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Middle East; Prospective Studies; Tablets; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan | 2015 |
A new, rapid, stability-indicating UPLC method for separation and determination of impurities in amlodipine besylate, valsartan and hydrochlorothiazide in their combined tablet dosage form.
Topics: Amlodipine; Antihypertensive Agents; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Hydrochlorothiazide; Limit of Detection; Reference Standards; Reproducibility of Results; Solutions; Tablets; Valsartan | 2015 |
[Sleep apnea: RR lowering drugs need to be administered in the evening].
Topics: Amlodipine; Blood Pressure; Cross-Over Studies; Drug Chronotherapy; Drug Therapy, Combination; Humans; Hypertension; Sleep Apnea, Obstructive; Tetrazoles; Valine; Valsartan | 2015 |
Protective effects of AT1-receptor blocker and CA antagonist combination on renal function in salt loaded spontaneously hypertensive rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Creatinine; Hydrogen-Ion Concentration; Kidney; Kidney Function Tests; Male; Proteinuria; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Urine; Valsartan | 2015 |
New methods for amlodipine and valsartan native spectrofluorimetric determination, with factors optimization study.
Topics: Amlodipine; beta-Cyclodextrins; Hypromellose Derivatives; Magnetite Nanoparticles; Reproducibility of Results; Spectrometry, Fluorescence; Surface-Active Agents; Valsartan | 2015 |
Simultaneous determination of valsartan, amlodipine besylate and hydrochlorothiazide using capillary zone electrophoresis (CZE).
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Calibration; Diuretics; Drug Combinations; Electrophoresis, Capillary; Hydrochlorothiazide; Limit of Detection; Reference Standards; Reproducibility of Results; Tablets; Tetrazoles; Valine; Valsartan | 2015 |
Improvement in Hemodynamics After Methylene Blue Administration in Drug-Induced Vasodilatory Shock: A Case Report.
Topics: Amlodipine; Atenolol; Hemodynamics; Humans; Male; Methylene Blue; Middle Aged; Shock; Valsartan; Vasodilation | 2015 |
Comparison of amlodipine/valsartan/hydrochlorothiazide single pill combination and free combination: adherence, persistence, healthcare utilization and costs.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Cohort Studies; Drug Combinations; Female; Hospitalization; Humans; Hydrochlorothiazide; Hypertension; Male; Medication Adherence; Middle Aged; Patient Acceptance of Health Care; Retrospective Studies; Valsartan | 2015 |
Clinical Effectiveness, Safety and Tolerability of Amlodipine/Valsartan in Hypertensive Patients: the Indonesian Subset of the EXCITE Study.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cough; Drug Combinations; Drug Substitution; Dyslipidemias; Edema; Female; Headache; Humans; Hypertension; Indonesia; Male; Medication Adherence; Middle Aged; Prospective Studies; Valsartan | 2015 |
The effect of fixed-dose combination of valsartan and amlodipine on nighttime blood pressure in patients with non-dipper hypertension.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cohort Studies; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Valsartan | 2016 |
Quantitative model for the blood pressure-lowering interaction of valsartan and amlodipine.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Healthy Volunteers; Humans; Models, Biological; Predictive Value of Tests; Valsartan | 2016 |
On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone.
Topics: Aged; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Valsartan | 2016 |
Development and Validation of highly Sensitive Stability Indicating Spectrofluorimetric Method for Determination of Amlodipine in Pharmaceutical Preparations and Human Plasma.
Topics: Amlodipine; Atorvastatin; Humans; Limit of Detection; Micelles; Pharmaceutical Preparations; Plasma; Spectrometry, Fluorescence; Tablets; Valsartan | 2016 |
Novel Pure Component Contribution Algorithm (PCCA) and UHPLC Methods for Separation and Quantification of Amlodipine, Valsartan, and Hydrochlorothiazide in Ternary Mixture.
Topics: Algorithms; Amlodipine; Antihypertensive Agents; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Tablets; Valsartan | 2017 |
Development, validation and comparison of near infrared and Raman spectroscopic methods for fast characterization of tablets with amlodipine and valsartan.
Topics: Amlodipine; Calibration; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Tablets; Tensile Strength; Time Factors; Valsartan | 2017 |
Oxidative stress: link between hypertension and diabetes.
Topics: Amlodipine; Diabetes Mellitus, Type 2; Humans; Hypertension; Oxidative Stress; Valsartan | 2017 |
Multiway analysis methods applied to the fluorescence excitation-emission dataset for the simultaneous quantification of valsartan and amlodipine in tablets.
Topics: Algorithms; Amlodipine; Calibration; Databases, Chemical; Factor Analysis, Statistical; Least-Squares Analysis; Spectrometry, Fluorescence; Tablets; Valsartan | 2017 |
mRNA levels of circadian clock components Bmal1 and Per2 alter independently from dosing time-dependent efficacy of combination treatment with valsartan and amlodipine in spontaneously hypertensive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Aorta; ARNTL Transcription Factors; Blood Pressure; Circadian Clocks; Drug Administration Schedule; Drug Therapy, Combination; Heart Ventricles; Hypertension; Kidney; Male; Period Circadian Proteins; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; RNA, Messenger; Valsartan | 2017 |
Combination cardiovascular drugs.
Topics: Aminobutyrates; Amlodipine; Aspirin; Biphenyl Compounds; Cardiovascular Agents; Cardiovascular Diseases; Drug Combinations; Humans; Nebivolol; Omeprazole; Perindopril; Tetrazoles; Valsartan | 2017 |
Blood pressure variability and risk of cardiovascular events and death in patients with hypertension and different baseline risks.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Mortality; Myocardial Infarction; Prognosis; Proportional Hazards Models; Stroke; Valsartan | 2018 |
Comparison of real-world effectiveness between valsartan and non-RAS inhibitor monotherapy on the incidence of new diabetes in Chinese hypertensive patients: An electronic health recording system based study.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; China; Diabetic Angiopathies; Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Valsartan | 2019 |
Perindopril 3.5 mg/amlodipine 2.5 mg versus renin-angiotensin system inhibitor monotherapy as first-line treatment in hypertension: a combined analysis.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Perindopril; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Valsartan | 2018 |
Effects of amlodipine and valsartan on glibenclamide-treated streptozotocin-induced diabetic rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Progression; Drug Interactions; Glyburide; Hypoglycemic Agents; Male; Rats, Wistar; Risk Assessment; Streptozocin; Time Factors; Valsartan | 2018 |
Identification and structure elucidation of a new degradation impurity in the multi-component tablets of amlodipine besylate.
Topics: Amlodipine; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Combinations; Drug Contamination; Drug Stability; Excipients; Formaldehyde; Hydrochlorothiazide; Magnetic Resonance Spectroscopy; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Time Factors; Valsartan | 2019 |
[THE COMBINED THERAPY IN HYPERTENSIVE PATIENTS WITH DYSLIPIDEMIA].
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Dyslipidemias; Fenofibrate; Humans; Hypertension; Hypolipidemic Agents; Middle Aged; Valsartan | 2018 |
Measuring Central or Peripheral Blood Pressure Levels? That is the Question in the Modern Clinical Practice of Hypertension.
Topics: Amlodipine; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Nebivolol; Valsartan | 2018 |
Low-dose combination therapy to control sustained ambulatory hypertension-Basic principles and future directions.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Nifedipine; Valsartan; Vascular Stiffness | 2019 |
A new strategy for taste masking on bitter drug by other combined drug in fixed-dose combination: bitterness of Amlodipine besylate could be masked efficiently by Valsartan.
Topics: Amlodipine; Benzazepines; Captopril; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Taste; Taste Perception; Telmisartan; Valsartan | 2019 |
Effects of Different Antihypertensive Drug Combinations on Blood Pressure and Arterial Stiffness.
Topics: Aged; Amlodipine; Antihypertensive Agents; Arteries; Blood Pressure; Diastole; Drug Combinations; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Lisinopril; Losartan; Male; Middle Aged; Prospective Studies; Pulse Wave Analysis; Systole; Valsartan; Vascular Resistance; Vascular Stiffness | 2019 |
Single-pill combination of cilnidipine, an L-/N-type calcium channel blocker, and valsartan effectively reduces home pulse pressure in patients with uncontrolled hypertension and sympathetic hyperactivity: The HOPE-Combi survey.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Humans; Hypertension; Tetrazoles; Valsartan | 2020 |
High performance liquid chromatographic assay of amlodipine, valsartan and hydrochlorothiazide simultaneously and its application to pharmaceuticals, urine and plasma analysis.
Topics: Amlodipine; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Limit of Detection; Linear Models; Reproducibility of Results; Tablets; Valsartan | 2020 |
Application of MEKC and UPLC with Fluorescence Detection for Simultaneous Determination of Amlodipine Besylate and Bisoprolol Fumarate.
Topics: Amlodipine; Antihypertensive Agents; Bisoprolol; Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Valsartan | 2021 |
Development and Validation of a UPLC-DAD Method for the Simultaneous Quantification of Eight Antihypertensive Drugs in the Pharmaceutical Matrix.
Topics: Amlodipine; Antihypertensive Agents; Humans; Hydrochlorothiazide; Pharmaceutical Preparations; Tetrazoles; Valsartan | 2021 |
Single-pill combination of cilnidipine, an l-/n-type calcium channel blocker, and valsartan reduces the day-by-day variability of morning home systolic blood pressure in patients with treated hypertension: A sub-analysis of the HOPE-combi survey.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Humans; Hypertension; Tetrazoles; Valsartan | 2021 |
Cancer Risk of Angiotensin II Receptor Blocker Valsartan: A Population-based Study.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Neoplasms; Tetrazoles; Valine; Valsartan | 2022 |
Eco-friendly spectrophotometric evaluation of triple-combination therapies in the treatment strategy of patients suffering from hypertension during coronavirus pandemic - Spectralprint recognition study.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Coronavirus; Humans; Hydrochlorothiazide; Hypertension; Leukemia, Myeloid, Acute; Pandemics; Spectrophotometry; Valsartan | 2022 |
Benefits of Valsartan and Amlodipine in Lipolysis through PU.1 Inhibition in Fructose-Induced Adiposity.
Topics: Activating Transcription Factor 3; Adiposity; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Fructose; Humans; Hypertension; Lipase; Lipolysis; Monoacylglycerol Lipases; Obesity; Stearoyl-CoA Desaturase; Tetrazoles; Triglycerides; Valsartan | 2022 |
Efficacy and safety of single pill combination of amlodipine and valsartan in hypertensive Saudi patients.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Humans; Hypertension; Leukemia, Myeloid, Acute; Prospective Studies; Saudi Arabia; Tetrazoles; Valsartan | 2023 |
Improved Persistence to Medication, Decreased Cardiovascular Events and Reduced All-Cause Mortality in Hypertensive Patients With Use of Single-Pill Combinations: Results From the START-Study.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; Medication Adherence; Retrospective Studies; Tetrazoles; Valsartan | 2023 |
Effect of Fixed-dose Combination Amlodipine/Valsartan in Comparison to Two Drug Combination Nebivolol/Valsartan on 24-Hour Ambulatory Blood Pressure.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Humans; Hypertension; Nebivolol; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2023 |
Effects of Valsartan and Amlodipine Tablets Combined with α-Lipoic Acid on T-AOC, IL-6 and β2-MG Levels in Patients with Diabetic Nephropathy.
Topics: Amlodipine; Antihypertensive Agents; Antioxidants; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Hypertension; Interleukin-6; Tablets; Thioctic Acid; Valsartan | 2023 |
Effects of 5-fluorouracil Co-administration on Blood Pressure in Patients Maintained on Antihypertensives: a Retrospective Case Series.
Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Fluorouracil; Humans; Hypertension; Nifedipine; Retrospective Studies; Tetrazoles; Valine; Valsartan | 2023 |
NITROSOGENESIS OF SKIN CANCER: THE NITROSAMINE CONTAMINATION IN THE CALCIUM CHANNEL BLOCKERS (AMLODIPINE), BETA BLOCKERS (BISOPROLOL), SARTANS (VALSARTAN/LOSARTAN), ACE INHIBITORS (PERINDOPRIL/ENALAPRIL), TRICYCLIC ANTIDEPRESSANTS (MELITRACEN), SSRIS (PAR
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antidepressive Agents, Tricyclic; Bisoprolol; Calcium Channel Blockers; Enalapril; Humans; Incidence; Losartan; Metformin; Paroxetine; Perindopril; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Skin Neoplasms; Valsartan; Venlafaxine Hydrochloride | 2023 |
NITROSOGENESIS OF CUTANEOUS MELANOMA: SIMULTANEOUSLY DEVELOPMENT OF PRIMARY CUTANEOUS THICK MELANOMA OF THE BREAST, THIN MELANOMA/DYSPLASTIC MOLE OF THE BACK DURING PARALLEL INTAKE OF BISOPROLOL, AMLODIPINE AND VALSARTAN/ HCT: NITROSAMINE POLYCONTAMINATIO
Topics: Amlodipine; Bisoprolol; Humans; Melanoma; Melanoma, Cutaneous Malignant; Mutagens; Skin Neoplasms; Valsartan | 2023 |
NITROSAMINE CONTAMINATION WITHIN CARDIAC MULTIMEDICATION - SARTANS (VALSARTAN), CALCIUM CHANNEL BLOCKERS (AMLODIPINE AND NIFEDIPINE), AND ANTIARRHYTHMICS (PROPAFENONE) AS A SIGNIFICANT FACTOR IN THE DEVELOPMENT AND PROGRESSION OF MULTIPLE KERATINOCYTIC CA
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Anti-Arrhythmia Agents; Calcium Channel Blockers; Carcinogens; Humans; Keratoacanthoma; Neoplasms; Nifedipine; Nitrosamines; Propafenone; Shoulder; Surgical Flaps; Valsartan | 2023 |