Page last updated: 2024-08-24

valsartan and amlodipine

valsartan has been researched along with amlodipine in 278 studies

Research

Studies (278)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (1.08)18.2507
2000's113 (40.65)29.6817
2010's137 (49.28)24.3611
2020's25 (8.99)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bodin, F; Cardoni, O; Corea, L; Fogari, R; Innocenti, P; Meilenbrock, S; Porcellati, C; Provvidenza, M; Sullivan, J1
Julius, S; Mann, J1
Julius, S1
Bertocchi, F; Bonaduce, D; Carretta, R; Condorelli, M; Fogari, R; Malacco, E; Mann, J; Palatini, P1
Bertocchi, F; Carretta, R; Di, SS; Dorigatti, F; Malacco, E; Mann, J; Palatini, P1
Dendorfer, A; Dodt, C; Handrock, R; Muck, P; Struck, J; Trübger, D; Weidinger, G1
Viberti, G; Wheeldon, NM1
Allen, TJ; Cao, Z; Cooper, ME; Davis, BJ; de Gasparo, M; Kawachi, H1
Handrock, R; Schmieder, RE1
Brunner, H; Ekman, S; Hansson, L; Julius, S; Kjeldsen, SE; Laragh, JH; McInnes, G; Platt, F; Schork, AM; Smith, B; Weber, M; Zanchetti, A1
Delles, C; Handrock, R; Klingbeil, AU; Schmieder, RE; Schneider, MP; Weidinger, G1
Borgnino, C; Capuano, V; Malacco, E; Palatini, P; Spagnuolo, V; Varì, N1
Eguchi, K; Hoshide, S; Hoshide, Y; Ishikawa, J; Ishikawa, S; Kario, K; Morinari, M; Shimada, K1
Franco, RJ; Goldflus, S; McQuitty, M; Oigman, W1
Hukai, D; Ishii, C; Kanamori, T; Ohbayashi, Y; Ohnishi, M; Ohno, K; Okabayashi, T; Ozawa, T; Sakaguchi, T; Sichiri, G; Tanaka, T; Tsutamoto, T; Tsutsui, T; Wada, A; Yokohama, H1
Delles, C; Handrock, R; Klingbeil, AU; Schäufele, T; Schmieder, RE; Schneider, MP1
Ambrosia, GB; Caiazza, A; Malacco, E; Mugellini, A; Palatini, P; Santonastaso, M; Spagnuolo, V1
Asada, A; Maeda, K; Nakamura, M; Watanabe, T; Yasunari, K; Yoshikawa, J1
Lindholm, LH1
Brunner, HR; Ekman, S; Hansson, L; Hua, T; Julius, S; Kjeldsen, SE; Laragh, J; McInnes, GT; Mitchell, L; Plat, F; Schork, A; Smith, B; Weber, M; Zanchetti, A1
Brunner, HR; Ekman, S; Hansson, L; Hua, T; Julius, S; Kjeldsen, SE; Laragh, JH; McInnes, GT; Mitchell, L; Plat, F; Schork, MA; Smith, B; Weber, MA; Zanchetti, A1
Epstein, M; Hollenberg, NK1
Bernaud, C; Boivin, JM; Fay, R; Radauceanu, A; Zannad, F1
Nilsson, PM1
Sever, P1
Zidek, W2
Berk, BC; Bisognano, JD1
Einecke, D1
Bertocchi, F; Dorigatti, F; Ferrara, R; Mugellini, A; Palatini, P; Spagnuolo, V; Varì, N1
Strauss, M; Verma, S1
Hedner, T; Himmelmann, A; Kjeldsen, SE1
Jackson, G1
Efstathiou, S; Makris, T; Manolis, A; Papavasiliou, M; Stergiou, GS1
Weber, MA1
Brandão, AA; Heintz, D; Kandra, A; Khder, Y; Ruilope, LM; Santonastaso, M; Stolt, P1
Kostis, WJ; Wilson, AC1
Bönner, G; Heintz, D; Kandra, A; Khder, Y; Malacco, E; Ruilope, LM1
Daley, W; Ferdinand, KC; Flack, JM; Jamerson, KA; Weir, MR; Zelenkofske, S1
Arosio, E; De Marchi, S; Lechi, A; Prior, M; Rigoni, A1
Coca, A; Ekman, S; Girerd, X; Hua, T; Jamerson, K; Julius, S; Kjeldsen, SE; Larochelle, P; MacDonald, TM; Mancia, G; McInnes, GT; Schmieder, RE; Schork, MA; Stolt, P; Viskoper, R; Weber, MA; Widimský, J; Zanchetti, A1
Aryana, A; Hilleman, DE; Maciejewski, S; Mohiuddin, SM; Mooss, AN; Packard, KA; Reyes, AP1
Ichihara, A; Kaneshiro, Y; Sakoda, M; Takemitsu, T1
Amerena, J; Balazovjech, I; Brunner, HR; Cassel, G; Herczeg, B; Hua, TA; Julius, S; Kjeldsen, SE; Koylan, N; Laragh, J; Magometschnigg, D; Majahalme, S; Martinez, F; McInnes, GT; Oigman, W; Schork, MA; Seabra Gomes, R; Weber, MA; Zanchetti, A; Zhu, JR1
Higaki, J; Okura, T1
Barker, TA; Berk, BC; Kennedy, AJ; Korshunov, VA; Massett, MP; Mohan, AM1
Ruilope, LM; Zanchetti, A1
Battegay, E; Calvo-Vargas, C; Cieśliński, A; Degaute, JP; Holwerda, NJ; Hua, T; Julius, S; Kjeldsen, S; Kobalava, J; Laragh, JH; McInnes, GT; Pedersen, OL; Plat, F; Rudyatmoko, FP; Siamopoulos, KC; Störset, O; Weber, M; Zanchetti, A1
Aslam, S; Leone, A; Santha, T; Wilcox, C1
Bizot, MN; Denouel, J; Dieterich, HA; Dole, WP; Kemp, C; Vaidyanathan, S; Valencia, J; Yeh, CM; Zhao, C1
Zoccali, C1
Albini, TA; Foroozan, R; Lakhanpal, RR; Lopez, GA; McPherson, AR1
Derosa, G; Fogari, E; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Rinaldi, A; Zoppi, A1
Birkenhäger, WH; Hansen, TW; Staessen, JA1
Høegholm, A; Julius, S; Kjeldsen, SE; Mancia, G; Nielsen, ES; Pedersen, OL; Pickering, T; Refsgaard, J; Weber, M1
Edelsberg, J; Jamerson, K; Khan, ZM; Kjeldsen, SE; Oster, G; Vincze, G; Weycker, D1
Assouline, L; de Champlain, J; Dubé, B; Karas, M; Larochelle, P; LeBlanc, AR; Nadeau, R1
Kashiwagi, A; Maegawa, H; Sawaguchi, M; Uzu, T2
Acikel, C; Caglar, K; Celik, T; Eyileten, T; Oguz, Y; Sonmez, A; Vural, A; Yavuz, I; Yenicesu, M; Yilmaz, MI1
Itoh, Y; Mori, Y; Tajima, N1
Chiang, YT; Fomina, I; Gamboa, R; Glazes, R; Kaczor, J; Kargiannis, S; Poldermans, D; Wernsing, M; Yen, J1
Bakris, GL; Glazer, R; Philipp, T; Smith, TR; Vaisse, B; Wernsing, M; Yen, J1
Glazer, R; Jin, J; Philipp, T; Pospiech, R; Schneider, H; Smith, TR; Wernsing, M; Yen, J1
Dong, YF; Ichijo, H; Kataoka, K; Kim-Mitsuyama, S; Matsuba, S; Ogawa, H; Shintaku, H; Tokutomi, Y; Yamamoto, E; Yamashita, T1
Campestrini, J; Dole, K; Dole, WP; He, YL; Howard, D; Ligueros-Saylan, M; Marion, A; Pommier, F; Sabo, R; Sunkara, G; Wang, Y; Zhao, C1
Krzesinski, JM; Scheen, AJ1
Plosker, GL; Robinson, DM1
Hua, TA; Julius, S; Kjeldsen, SE; McInnes, GT; Schmieder, RE; Zanchetti, A1
Allemann, Y; Barbier, M; Ferber, P; Fraile, B; Izzo, JL; Lambert, M1
Corradi, L; Derosa, G; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Zoppi, A1
Daimon, M; Fujita, M; Komuro, I; Kuwabara, Y; Mizuma, H; Nakayama, K; Narumi, H; Shindo, S1
Asai, S; Ishikawa, K; Nishida, Y; Sugahara-Kobayashi, M; Takahashi, Y1
Hirooka, Y; Ito, K; Kimura, Y; Sagara, Y; Sunagawa, K1
Botha, J; DeAngelis, L; Ferber, P; Kandra, A; Karalliedde, J; Mirenda, V; Smith, A; Viberti, G1
Croce, G; Desideri, G; Ferri, C1
Ansari, A; Brachmann, J; Handrock, R; Klebs, S; Mahla, G1
Aksnes, TA; Hua, TA; Julius, S; Kjeldsen, SE; Rostrup, M; Störset, O1
Corradi, L; Derosa, G; Ferrari, I; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Santoro, T; Zoppi, A1
Ferguson, KL; Greller, HA; Hoffman, RS; Nelson, LS; Smith, SW1
Anthony Schork, M; Coca, A; Girerd, X; Hua, TA; Jamerson, K; Julius, S; Kjeldsen, SE; Larochelle, P; Macdonald, T; Mancia, G; McInnes, GT; Schmieder, RE; Viskoper, R; Weber, MA; Widimsky, J; Zanchetti, A1
Mourad, JJ; Waeber, B1
Brixner, DI; Jackson, KC; Keskinaslan, A; Nelson, RE; Sheng, X1
Fujikawa, K; Saito, I; Saruta, T1
Corradi, L; Derosa, G; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Santoro, T; Zoppi, A1
Belousov, DIu; Belousov, IuB; Shestakova, MV1
Glazer, RD; Kavoliuniene, A; Miglinas, M; Prak, H; Sinkiewicz, W; Wernsing, M; Yen, J1
Ansari, A; Braun, N; Handrock, R; Klebs, S; Ulmer, HJ1
Akpinar, E; Brunel, P; Calvo, C; Keeling, L; Salvetti, A; Schrader, J; Weisskopf, M1
Edelsberg, J; Kartashov, A; Keskinaslan, A; Levy, DG; Oster, G; Weycker, D1
Borbas, E; Handrock, R; Klebs, S; Schaetzl, R; Trenkwalder, P1
Ram, CV1
Glazer, RD; Philipp, T; Pospiech, R; Zhao, Y1
Ichihara, A; Itoh, H; Kaneshiro, Y; Kinouchi, K; Kurauchi-Mito, A; Sakoda, M1
Mullangi, R; Ramani, AV; Sengupta, P1
Black, HR; Lacourcière, Y; Purkayastha, D; Samuel, R; Wright, JT; Zappe, D2
Black, HR1
Calhoun, DA; Chiang, YT; Glazer, RD; Lacourcière, Y1
Flack, JM; Hilkert, R1
Vivencio, B1
Glazer, RD; Macarie, CE; Romanova, J; Schunkert, H; Vintila, MM; Wernsing, M; Yen, J1
Frampton, JE; Scott, LJ1
Ferber, P; Papst, CC; Zappe, D1
Deeks, ED1
Divchev, D; Grothusen, A; Luchtefeld, M; Schieffer, B1
Chen, X; Dong, J; Jiang, L; Jiang, W; So, Y; Xin, H1
Calhoun, DA; Crikelair, NA; Glazer, RD; Yen, J1
Huang, J; Ke, YN; Zhu, JR1
Corradi, L; Derosa, G; Fogari, R; Malamani, G; Mugellini, A; Preti, P; Zoppi, A1
Derosa, G; Fogari, R; Mugellini, A; Preti, P; Zoppi, A1
Achouba, A; Boutouyrie, P; Laurent, S; Trunet, P1
Cagnoni, F; D'Ospina, A; Demichele, E; Destro, M; Peros, E; Preti, P; Ricci, AR; Zaninelli, A1
Kondo, T; Maeda, K; Matsushita, K; Muramatsu, T; Murohara, T; Shintani, S1
Blanco-Colio, LM; Carrero, JJ; Celik, T; Egido, J; Eyileten, T; Martín-Ventura, JL; Moreno, JA; Saglam, M; Sonmez, A; Yaman, H; Yenicesu, M; Yilmaz, MI1
Cardenas, P; Hong, H; Ke, Y; Wang, R; Zhang, Y; Zhu, D; Zhu, J1
Deedwania, PC; Egan, BM; Jialal, I; Ofili, EO; Purkayastha, D; Raij, L; Samuel, R; Sowers, JR; Zappe, DH1
Ayala, DE; Fernández, JR; Fontao, MJ; Hermida, RC; Mojón, A1
Derosa, G; Ferrari, I; Fogari, R; Mugellini, A; Preti, P; Zoppi, A1
Desilva, VR; Enomoto, D; Higaki, J; Irita, J; Jotoku, M; Kurata, M; Miyoshi, K; Nagao, T; Okura, T1
Hilleman, DE; Malesker, MA1
Bilo, G; Mancia, G; Parati, G; Schumacher, H1
Ayalasomayajula, S; Bhad, P; Jarugula, V; Karan, R; Leon, S; Riviere, GJ; Sunkara, G1
Crikelair, N; Destro, M; Glazer, R; Yen, J1
Belal, TS; Shaalan, RA1
Aritomi, S; Koganei, H; Konda, T; Mitsui, A; Nitta, K; Ogawa, T; Wagatsuma, H1
Fujita, M; Komuro, I; Kuwabara, Y; Mizuma, H; Narumi, H; Shindo, S; Takano, H1
Giles, T; Hilkert, R; Ofili, EO; Oparil, S; Pitt, B; Samuel, R; Seifu, Y; Sowers, JR1
Barrios, V; Escobar, C1
Chazova, IE; Dongre, N; Vigdorchik, AV1
Calhoun, DA; Crikelair, N; Glazer, RD; Lacourcière, Y; Yen, J1
Aritomi, S; Konda, T; Niinuma, K; Nitta, K; Ogawa, T2
Bekki, H; Fukami, K; Homma, T; Nakata, M; Nohara, M; Okuda, S; Sone, M; Yamagishi, S; Yamamoto, K1
Curt, V; Hao, YM; Huang, J; Sun, NL; Tu, Y; Zhang, Y; Zhu, JR1
Aderibigbe, A; Anisiuba, BC; Ba, SA; Boombhi, HJ; Ijoma, CK; Kamdem, MK; Kaptue, J; Kingue, S; Kolo, PM; Lemogoum, D; M'buyamba-Kabangu, JR; Mipinda, JB; Ndiaye, MB; Odili, AN; Omotoso, BA; Richart, T; Staessen, JA; Thijs, L; Ulasi, II1
Higashi, K; Hiroo, K; Kushiyama, T; Oda, T; Yamamoto, K1
Andrews, LM; Baser, O; Wang, L; Xie, L1
Duprez, D; Ferdinand, KC; Purkayastha, D; Samuel, R; Wright, RF1
Dong, YF; Kataoka, K; Kim-Mitsuyama, S; Koibuchi, N; Nakamura, T; Nako, H; Ogawa, H; Sueta, D; Tokutomi, Y; Toyama, K; Yamamoto, E1
Bagmanova, NKh; Fediunina, EIu; Karaulova, IuL; Kobalava, ZhD; Kotovskaia, IuV1
Egan, BM; Purkayastha, D; Raij, L; Samuel, R; Sowers, JR; Zappe, DH1
Hasegawa, H; Kobayashi, Y; Komuro, I; Kuwabara, Y; Mizuma, H; Narumi, H; Shindo, S; Takano, H1
Chrysant, SG1
Christogiannis, LG; Elisaf, MS; Kostapanos, MS; Milionis, HJ; Tellis, CC; Tselepis, AD1
Cai, J; Cheng, K; Huang, Z; Ming, Y; Yang, G; Ye, Q; Yuan, H; Zhou, P; Zuo, X1
Duprez, D; Ferdinand, K; Purkayastha, D; Samuel, R; Wright, R1
Ichimiya, S; Ikeda, N; Kondo, T; Maeda, K; Matsushita, K; Muramatsu, T; Murohara, T; Ohno, M; Shintani, S; Sone, T; Watarai, M; Yamashita, K1
Ofili, EO; Purkayastha, D; Samuel, R; Sowers, JR; Zappe, DH1
Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Perrone, T; Preti, P; Zoppi, A1
Pancholi, SS; Sharma, RN1
Sun, CX; Tao, CW; Wu, ZB; Yu, QG; Zhang, Y1
Derosa, G; Fogari, R; Maffioli, P; Mugellini, A; Preti, P; Zoppi, A1
Ikeda, M; Ohta, M; Tajiri, Y; Yamato, H1
Barrios, V; de la Sierra, A1
Gao, P; Grosso, A; Sun, N; Wang, R; Yang, K; Zhang, Y; Zhu, D1
Chen, JF; Hung, YJ; Lee, IT; Lee, WJ; Sheu, WH; Wang, CY2
Kaynar, K; Konca, C; Ozkan, G; Ulusoy, S1
Chen, CS; Cheng, SM; Hsieh, CM; Huang, LC; Huang, SC; Mar, GY; Ueng, KC1
Brunner, HR; Hua, TA; Jia, Y; Julius, S; Kjeldsen, SE; Mancia, G; McInnes, GT; Schork, A; Weber, MA; Zanchetti, A; Zappe, DH1
Dohi, K; Hiraoka, N; Hoshino, K; Ito, M; Kitai, T; Kumagai, N; Nakamori, S; Nakamura, M; Okamoto, S; Onishi, K; Oota, M; Ueda, Y; Yamada, T; Yazu, T1
Baek, I; Haesler, E; Hayoz, D; Joly, MP; Kandra, A; Mazzolai, L; Meyer, MA; Periard, D; Zappe, DH1
Arslan, E; Ay, SA; Balta, S; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Sağlam, K; Turker, T; Unlu, M; Yaman, H1
Akhan, M; Arslan, E; Arslan, Z; Ay, SA; Balta, S; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Saglam, K; Sarlak, H1
Goto, SN; Mizuno, Y; Takagi, H; Umemoto, T; Yamamoto, H1
Huang, J; Huang, Y; Wang, T1
Arslan, Z; Balta, S; Bozoglu, E; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Kocak, N; Kurt, O; Naharci, I; Sarlak, H; Seyit Ahmet, AY1
Kothari, C; Mehta, P; Sharma, M; Sherikar, O1
Akhan, M; Altun, B; Arslan, E; Ay, SA; Balta, S; Bulucu, F; Cakar, M; Demirkol, S; Karaman, M; Koc, B; Kurt, O; Unlu, M1
Aoyama, T; Goto, M; Goto, N; Hiei, K; Iwasa, M; Kawai, N; Kida, K; Kobayashi, H; Kojima, S; Minagawa, T; Minatoguchi, S; Oda, M; Sugishita, F; Takai, K; Tanaka, R; Watanabe, I; Yamamoto, N; Yasue, T1
Freytag, S; Hagendorff, A; Klebs, S; Müller, A1
Arslan, E; Ay, SA; Balta, S; Bozoglu, E; Bulucu, F; Cakar, M; Celik, T; Demirbas, S; Demirkol, S; Karaman, M; Kurt, O; Naharci, MI1
Aksenova, AV; Chazova, IE; Elfimova, EM; Galitsin, PV; Litvin, AY; Rogoza, AN; Sukmarova, ZN1
Eckert, S; Freytag, SB; Klebs, SH; Müller, A1
Calhoun, DA; Crikelair, N; Glazer, RD; Jia, Y; Lacourcière, Y1
Darwish, HW; El-Zeany, BA; Hassan, SA; Salem, MY2
Anisiuba, BC; Ba, SA; Boombhi, HJ; Ezeala-Adikaibe, B; Ijoma, CK; Jacobs, L; Kaptue, J; Kingue, S; Kolo, PM; Lemogoum, D; M'Buyamba-Kabangu, JR; Mipinda, JB; Ndiaye, MB; Odili, A; Omotoso, BA; Osakwe, CE; Staessen, JA; Thijs, L; Ulasi, II1
Bahng, MY; Chae, D; Kim, Y; Lee, D; Park, K; Roh, H; Son, H; Son, M1
Berktaş, M; Boyacı, B; Kızılırmak, P; Yalçın, MR1
Gnudi, L; Hill, B; Karalliedde, J; Maltese, G; Viberti, G1
Kondo, T; Maeda, K; Matsushita, K; Muramatsu, T; Murohara, T; Nagahiro, T; Shintani, S; Yamashita, K1
Akasaka, H; Miura, T; Saitoh, S; Shimamoto, K; Yoshida, H1
Ar, I; Ilerigelen, B; Kızılırmak, P1
Kartashova, EA; Romantsov, MG; Sarvilina, IV1
Izumikawa, Y; Kato, H; Kojima, K; Kubo, E; Nagura, M; Nosaka, H; Shima, T; Shimada, M; Shiraishi, T; Tanemoto, M; Tomioka, S; Uchida, S; Ueda, S; Yano, H1
Kobalava, ZhD; Kotovskaia, IuV; Kravtsova, OA; Lobzhanidze, TV1
Harada, E; Hattori, T; Matsuura, N; Murohara, T; Nagasawa, K; Nagata, K; Niinuma, K; Takahashi, K; Takatsu, M; Watanabe, S1
Greenwood, JP; Negrou, K; Oliver, JJ; Plein, S; Ripley, DP; Struthers, AD; Worthy, G1
Andrikou, I; Aragiannis, D; Bilo, G; Dimitriadis, K; Filis, K; Kasiakogias, A; Parati, G; Sideris, S; Stefanadis, C; Thomopoulos, C; Tsiachris, D; Tsioufis, C1
Amodeo, C; Asmar, R; Chazova, IE; Gamba, MA; Mancia, G; Mourad, JJ; Puig, JG; Taddei, S1
Ahmet Ay, S; Balta, S; Celık, T; Demırkol, S; Dınc, M; Fıcı, F; Grassı, G; Iyısoy, A; Karaman, M; Kılıc, S; Kurt, G; Ozturk, C; Quartı-Trevano, F; Tas, A; Unal, HU; Yılmaz, MI1
Hegazy, MA; Lotfy, HM; Mohamed, EH; Mowaka, S2
Assaad-Khalil, SH; Cho, B; DiTommaso, S; Kitchlew, AR; Najem, R; Shete, A; Sison, J; Ueng, KC1
Coufal, P; Janečková, L; Jedlička, A; Vojta, J1
Atanasovska, E; Cekovska, S; Gjorgjievska, K; Jurhar-Pavlova, M; Pavlovska, K; Zafirov, D; Zendelovska, D1
Ayad, MF; El-Kosasy, AM; Sheta, AI; Tawakkol, SM1
Ebeid, W; El-Bagary, R; Elkady, E; Elzahr, A; Patonay, G; Salim, M1
Anraku, Y; Inami, S; Inoue, T; Kato, T; Kikegawa, Y; Nakamoto, A; Node, K; Suzuki, A; Toyoda, S; Tsukada, K1
Adachi, S; Fujisawa, K; Inoue, T; Kusumoto, T; Miura, S; Motozato, K; Saku, K; Shiga, Y1
Cole, JB; Laes, JR; Williams, DM1
Chen, W; Kahler, KH; Machnicki, G; Ong, SH; Wei, ZJ1
Bangalore, S; Berge, E; Holzhauer, B; Hua, TA; Julius, S; Kjeldsen, SE; Mancia, G; Messerli, FH; Weber, MA; Zanchetti, A; Zappe, D1
Abdillah, A; Kalim, H; Setiawati, A1
Aksnes, TA; Holzhauer, B; Hua, TA; Julius, S; Kjeldsen, SE; Rostrup, M1
Akkaya, N; Cakmak, M; Çelik, HT; Demircelik, B; Erdamar, H; Gok, S; Kazanci, F; Yigitoglu, R1
Greeley, M; Hsiao, HL; Langenickel, TH; Pal, P; Rajman, I; Rebello, S; Roberts, J; Sunkara, G; Zhou, W1
Akçay, S; Aksoy, F; Erdoğan, D; Ersoy, İ; İçli, A; Özaydın, M; Yücel, H1
Heo, YA; Holford, N; Kim, Y; Park, K; Son, M1
Fujii, M; Ichikawa, M; Imagawa, M; Ishizuka, T; Kaeriyama, S; Konoshita, T; Makino, Y; Nakamura, H; Nakaya, T; Sato, S; Suzuki, J; Urabe, M; Wakahara, S; Yamada, M; Yamamoto, K; Zenimaru, Y1
Hammad, MA; Mohamed, AA; Mohamed, AI; Omar, MA1
Hafeez, K; Jia, Y; Sibulo, A; Wang, JG; Yukisada, K; Zhang, J1
Chen, X; Liu, K; Liu, Q; Shi, D; Shi, R1
Casian, T; De Beer, T; Reznek, A; Tomuță, I; Van Renterghem, J; Vonica-Gligor, AL1
Moon, JS; Won, KC1
Ahn, YB; Choi, SH; Han, SJ; Jang, HC; Kim, DJ; Kim, HJ; Kim, HY; Kim, NH; Kim, SH; Kim, TH; Kim, YH; Ko, SH; Lee, KW; Lim, S; Seo, JA; Shin, DH1
Büker, E; Dinç, E; Ertekin, ZC1
Doka, G; Klimas, J; Kralova, E; Krenek, P; Potucek, P; Radik, M1
Bridgeman, MB; Dalal, KS1
Albrecht, D; Blaak, EE; Engeli, S; Goossens, GH; Haufe, S; Havekes, B; Heise, T; Jax, T; Jordan, J; Langenickel, TH; May, M; Pal, P; Stinkens, R; Tegtbur, U1
Berge, E; Hua, TA; Julius, S; Kjeldsen, SE; Liestøl, K; Mancia, G; Mehlum, MH; Parati, G; Rothwell, PM; Weber, MA1
Albrecht, D; Blaak, EE; Engeli, S; Goossens, GH; Hartmann, N; Havekes, B; Heise, T; Jax, T; Jocken, JW; Jordan, J; Kaiser, S; Langenickel, TH; Letzkus, M; May, M; Schaper, N; Schindler, C; Stinkens, R; van der Kolk, BW1
Shen, T; Wang, J; Yu, J; Yu, Y1
Laurent, S; Mancia, G; Poulter, N1
Bafor, EE; Bolanle, IO; Omogbai, EKI1
Břicháč, J; Douša, M; Gibala, P; Kalášek, S; Kalužíková, A; Štefko, M; Tkadlecová, M1
Gegeshidze, N; Kapetivadze, V; Lazashvili, T; Maglapheridze, Z; Tabukashvili, R; Tchaava, K1
Presta, V; Tocci, G1
Georgianos, PI; Liakopoulos, V; Zebekakis, PE1
Cho, S; Gwon, MR; Kang, WY; Kim, BK; Lee, HW; Ohk, B; Seong, SJ; Yang, DH; Yoon, YR1
Asmar, R; Brzozowska-Villatte, R; de Champvallins, M; Dominiczak, AF1
Habara, M; Haraguchi, T; Ikezaki, H; Kojima, H; Nakamura, S; Uchida, T; Yoshida, M1
Kim, JR; Kim, S; Ko, JW1
Hebibovic, S; Jatic, Z; Rustempasic, E; Skopljak, A; Sukalo, A; Valjevac, A1
Bianco, HT; Ferreira, CES; Figueiredo Neto, AM; Fonseca, FAH; França, CN; Izar, MCO; Kato, JT; Massunaga, ND; Póvoa, RMS1
Hanada, H; Higaki, J; Higashiura, K; Horio, T; Hosomi, N; Igase, M; Ishimitsu, T; Iwashima, Y; Kamide, K; Katabuchi, R; Kato, J; Kawano, Y; Kojima, S; Komai, N; Matsuura, H; Miki, T; Miwa, Y; Miyata, T; Morimoto, S; Nakahama, H; Nakahashi, T; Nakamura, S; Ohta, Y; Oukura, T; Rakugi, H; Sasaguri, T; Sase, K; Shimamoto, K; Shinagawa, T; Soma, M; Sugimoto, K; Takeda, K; Takiuchi, S; Tomohiro Katsuya, T; Tsuchihashi, T; Ueno, M; Yoshihara, F1
Kario, K; Kurose, Y; Matsuda, S; Nagahama, S; Sugii, H; Suzuki, N; Teshima, T2
Berge, E; Julius, S; Kjeldsen, SE; Liestøl, K; Mancia, G; Mehlum, MH; Parati, G; Rothwell, PM; Weber, MA; Wyller, TB1
Khairat, I; Khedr, L; Werida, R1
Abdul, A; Pathan, MAAK; Raut, S; Shaikh, JSA1
Chen, LC; Chiang, CE; Leu, HB; Lu, TM; Wang, KL; Yu, WC1
Bots, ML; Groenland, EH; Spiering, W; van der Elst, KCM; van Kleef, MEAM; Visseren, FLJ1
Ahmed, HM; Belal, TS; El Yazbi, FA; Elonsy, SM; Shaalan, RA1
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Chan, TH; Tsoi, MF; Yung Cheung, BM1
Chen, W; Hua, Z; Li, Y; Wang, Y; Zhu, Y1
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Chou, CL; Fang, TC; Li, CH1
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Liang, H; Tang, T; Xie, M1
Tchernev, G3

Reviews

20 review(s) available for valsartan and amlodipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Long-term potential of angiotensin receptor blockade for cardiovascular protection in hypertension: the VALUE trial. Valsartan Antihypertensive Long-term Use Evaluation.
    Cardiology, 1999, Volume: 91 Suppl 1

    Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Hypertension; Tetrazoles; Valine; Valsartan

1999
The VALUE trial: a commentary.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2004, Volume: 5, Issue:3

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Administration Schedule; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan

2004
[VALUE].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, Volume: 64 Suppl 6

    Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Double-Blind Method; Endpoint Determination; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Randomized Controlled Trials as Topic; Risk; Tetrazoles; Valine; Valsartan

2006
Asymmetric dimethylarginine in end-stage renal disease patients: a biomarker modifiable by calcium blockade and angiotensin II antagonism?
    Kidney international, 2006, Volume: 70, Issue:12

    Topics: Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Arginine; Biomarkers; Calcium; Calcium Channel Blockers; Humans; Kidney Failure, Chronic; Risk Factors; Tetrazoles; Valine; Valsartan

2006
[A first drug combination for the treatment of arterial hypertension with a calcium channel antagonist (amlodipine besylate) and an angiotensin receptor blocker (valsartan): Exforge].
    Revue medicale de Liege, 2007, Volume: 62, Issue:11

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Drug Combinations; Humans; Hypertension; Tetrazoles; Valine; Valsartan

2007
Amlodipine/Valsartan: fixed-dose combination in hypertension.
    Drugs, 2008, Volume: 68, Issue:3

    Topics: Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Drug Combinations; Drug Synergism; Humans; Hypertension; Tetrazoles; Valine; Valsartan

2008
Role of combination therapy in the treatment of hypertension: focus on valsartan plus amlodipine.
    Advances in therapy, 2008, Volume: 25, Issue:4

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hypertension; Life Style; Tetrazoles; Valine; Valsartan

2008
Antihypertensive efficacy of olmesartan medoxomil or valsartan in combination with amlodipine: a review of factorial-design studies.
    Current medical research and opinion, 2009, Volume: 25, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Olmesartan Medoxomil; Placebos; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan

2009
Single-pill combination of amlodipine and valsartan in the management of hypertension.
    Expert opinion on pharmacotherapy, 2009, Volume: 10, Issue:12

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Humans; Hypertension; Patient Compliance; Tetrazoles; Valine; Valsartan

2009
Amlodipine/valsartan single-pill combination: a review of its use in the management of hypertension.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2009, Volume: 9, Issue:5

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Drug Interactions; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2009
Angiotensin II type 1 receptor blockade: high hopes sent back to reality?
    Minerva cardioangiologica, 2009, Volume: 57, Issue:6

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Consensus; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Follow-Up Studies; Heart Failure; Hospitalization; Humans; Hypertension; Hypertrophy, Left Ventricular; Middle Aged; Practice Guidelines as Topic; Primary Prevention; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Risk Factors; Saralasin; Secondary Prevention; Stroke; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan

2009
Evaluating 24-h antihypertensive efficacy by the smoothness index: a meta-analysis of an ambulatory blood pressure monitoring database.
    Journal of hypertension, 2010, Volume: 28, Issue:11

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Databases, Factual; Female; Humans; Losartan; Male; Ramipril; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2010
Valsartan-amlodipine-hydrochlorothiazide: the definitive fixed combination?
    Expert review of cardiovascular therapy, 2010, Volume: 8, Issue:11

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Medication Adherence; Tetrazoles; Treatment Outcome; Valine; Valsartan

2010
Single-pill triple-combination therapy: an alternative to multiple-drug treatment of hypertension.
    Postgraduate medicine, 2011, Volume: 123, Issue:6

    Topics: Amides; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Design; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Medication Adherence; Olmesartan Medoxomil; Practice Guidelines as Topic; Practice Patterns, Physicians'; Tetrazoles; Valine; Valsartan

2011
Blood pressure control with angiotensin receptor blocker-based three-drug combinations: key trials.
    Advances in therapy, 2012, Volume: 29, Issue:5

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan

2012
Effects of telmisartan therapy on interleukin-6 and tumor necrosis factor-alpha levels: a meta-analysis of randomized controlled trials.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2013, Volume: 36, Issue:4

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Benzoates; Blood Pressure; Calcium Channel Blockers; Confidence Intervals; Cross-Over Studies; Double-Blind Method; Humans; Hypertension; Hypertension, Renal; Imidazoles; Interleukin-6; Obesity; Prospective Studies; Publication Bias; Randomized Controlled Trials as Topic; Stents; Telmisartan; Tetrazoles; Tumor Necrosis Factor-alpha; Valine; Valsartan

2013
Meta-analysis of three observational studies of amlodipine/valsartan in hypertensive patients with additional risk factors.
    Blood pressure, 2013, Volume: 22 Suppl 1

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Obesity, Abdominal; Risk Factors; Tetrazoles; Valine; Valsartan

2013
Plasma Trough Concentrations of Antihypertensive Drugs for the Assessment of Treatment Adherence: A Meta-Analysis.
    Hypertension (Dallas, Tex. : 1979), 2021, Volume: 77, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Humans; Hydrochlorothiazide; Hypertension; Treatment Adherence and Compliance; Valsartan

2021
Efficacy of single-pill combination in uncontrolled essential hypertension: A systematic review and network meta-analysis.
    Clinical cardiology, 2023, Volume: 46, Issue:8

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Network Meta-Analysis; Telmisartan; Tetrazoles; Valine; Valsartan

2023

Trials

145 trial(s) available for valsartan and amlodipine

ArticleYear
Valsartan, a new angiotensin II antagonist for the treatment of essential hypertension: a comparative study of the efficacy and safety against amlodipine.
    Clinical pharmacology and therapeutics, 1996, Volume: 60, Issue:3

    Topics: Adult; Aged; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Dizziness; Double-Blind Method; Drug Administration Schedule; Edema; Female; Headache; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

1996
The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial of cardiovascular events in hypertension. Rationale and design.
    Blood pressure, 1998, Volume: 7, Issue:3

    Topics: Aged; Amlodipine; Angiotensin II; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Prospective Studies; Research Design; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan

1998
Long-term potential of angiotensin receptor blockade for cardiovascular protection in hypertension: the VALUE trial. Valsartan Antihypertensive Long-term Use Evaluation.
    Cardiology, 1999, Volume: 91 Suppl 1

    Topics: Amlodipine; Animals; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Humans; Hypertension; Tetrazoles; Valine; Valsartan

1999
A multicenter, randomized double-blind study of valsartan/hydrochlorothiazide combination versus amlodipine in patients with mild to moderate hypertension.
    Journal of hypertension, 2001, Volume: 19, Issue:9

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan

2001
Trough:peak ratio and smoothness index in the evaluation of 24-h blood pressure control in hypertension: a comparative study between valsartan/hydrochlorothiazide combination and amlodipine.
    European journal of clinical pharmacology, 2002, Volume: 57, Issue:11

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Valine; Valsartan

2002
Effects of selective angiotensin II receptor blockade on sympathetic nerve activity in primary hypertensive subjects.
    Journal of hypertension, 2002, Volume: 20, Issue:6

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Heart Rate; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Muscle, Skeletal; Receptor, Angiotensin, Type 1; Sympathetic Nervous System; Tetrazoles; Valine; Valsartan; Vasodilator Agents

2002
Microalbuminuria reduction with valsartan in patients with type 2 diabetes mellitus: a blood pressure-independent effect.
    Circulation, 2002, Aug-06, Volume: 106, Issue:6

    Topics: Adult; Aged; Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2002
[Control of systolic blood pressure in the VALUE trial after 12 months].
    Deutsche medizinische Wochenschrift (1946), 2003, Mar-07, Volume: 128, Issue:10

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Double-Blind Method; Europe; Female; Germany; Humans; Hypertension; Male; Middle Aged; Prognosis; Reference Standards; Risk Factors; Tetrazoles; Valine; Valsartan

2003
VALUE trial: Long-term blood pressure trends in 13,449 patients with hypertension and high cardiovascular risk.
    American journal of hypertension, 2003, Volume: 16, Issue:7

    Topics: Algorithms; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Cohort Studies; Double-Blind Method; Drug Utilization; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Risk; Tetrazoles; Valine; Valsartan

2003
Direct comparison of the effects of valsartan and amlodipine on renal hemodynamics in human essential hypertension.
    American journal of hypertension, 2003, Volume: 16, Issue:12

    Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Glomerular Filtration Rate; Humans; Hypertension; Microcirculation; Middle Aged; Renal Circulation; Tetrazoles; Valine; Valsartan

2003
A randomized, double-blind, active-controlled, parallel-group comparison of valsartan and amlodipine in the treatment of isolated systolic hypertension in elderly patients: the Val-Syst study.
    Clinical therapeutics, 2003, Volume: 25, Issue:11

    Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Sodium Chloride Symporter Inhibitors; Systole; Tetrazoles; Valine; Valsartan

2003
Comparison of valsartan and amlodipine on ambulatory and morning blood pressure in hypertensive patients.
    American journal of hypertension, 2004, Volume: 17, Issue:2

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Chronotherapy; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2004
Efficacy and tolerability of the combination valsartan/hydrochlorothiazide compared with amlodipine in a mild-to-moderately hypertensive Brazilian population.
    Blood pressure. Supplement, 2003, Volume: 2

    Topics: Aged; Amlodipine; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brazil; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Racial Groups; Tetrazoles; Treatment Outcome; Valine; Valsartan

2003
Effect of an angiotensin II type 1 receptor blocker, valsartan, on neurohumoral factors in patients with hypertension: comparison with a long-acting calcium channel antagonist, amlodipine.
    Journal of cardiovascular pharmacology, 2003, Volume: 42 Suppl 1

    Topics: Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Coronary Disease; Delayed-Action Preparations; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Natriuretic Peptide, Brain; Neurotransmitter Agents; Norepinephrine; Receptor, Angiotensin, Type 1; Tetrazoles; Time Factors; Valine; Valsartan

2003
Comparison of the effects on 24-h ambulatory blood pressure of valsartan and amlodipine, alone or in combination with a low-dose diuretic, in elderly patients with isolated systolic hypertension (Val-syst Study).
    Blood pressure monitoring, 2004, Volume: 9, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Diuretics; Drug Therapy, Combination; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2004
Comparative effects of valsartan versus amlodipine on left ventricular mass and reactive oxygen species formation by monocytes in hypertensive patients with left ventricular hypertrophy.
    Journal of the American College of Cardiology, 2004, Jun-02, Volume: 43, Issue:11

    Topics: Amlodipine; Antihypertensive Agents; Cross-Sectional Studies; Double-Blind Method; Echocardiography; Female; Flow Cytometry; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Monocytes; Prospective Studies; Reactive Oxygen Species; Tetrazoles; Treatment Outcome; Valine; Valsartan

2004
Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial.
    Lancet (London, England), 2004, Jun-19, Volume: 363, Issue:9426

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diuretics; Double-Blind Method; Endpoint Determination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Factors; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome; Valine; Valsartan

2004
Differential time effect profiles of amlodipine, as compared to valsartan, revealed by ambulatory blood pressure monitoring, self blood pressure measurements and dose omission protocol.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:4

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Time Factors; Valine; Valsartan

2004
Ambulatory versus clinic blood pressure for the assessment of anti hypertensive efficacy in clinical trials: insights from the Val-Syst Study.
    Clinical therapeutics, 2004, Volume: 26, Issue:9

    Topics: Aged; Aged, 80 and over; Ambulatory Care Facilities; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Male; Patient Selection; Tetrazoles; Treatment Outcome; Valine; Valsartan

2004
Comparison of antihypertensive effects of an angiotensin-converting enzyme inhibitor, a calcium antagonist and a diuretic in patients with hypertension not controlled by angiotensin receptor blocker monotherapy.
    Journal of hypertension, 2005, Volume: 23, Issue:4

    Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chlorthalidone; Cross-Over Studies; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2005
24-hour ambulatory blood-pressure effects of valsartan and hydrochlorothiazide combinations compared with amlodipine in hypertensive patients at increased cardiovascular risk: a VAST sub-study.
    Blood pressure monitoring, 2005, Volume: 10, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan

2005
Efficacy and tolerability of combination therapy with valsartan plus hydrochlorothiazide compared with amlodipine monotherapy in hypertensive patients with other cardiovascular risk factors: the VAST study.
    Clinical therapeutics, 2005, Volume: 27, Issue:5

    Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cerebrovascular Disorders; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Male; Middle Aged; Myocardial Infarction; Obesity; Risk Factors; Tetrazoles; Valine; Valsartan

2005
A noninferiority comparison of valsartan/hydrochlorothiazide combination versus amlodipine in black hypertensives.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:3

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Black People; Blood Pressure; Calcium Channel Blockers; Diuretics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan

2005
Haemodynamic effects of AT1 inhibition and Ca2+-channel blockade in hypertensive patients during isometric stress.
    Journal of human hypertension, 2006, Volume: 20, Issue:3

    Topics: Amlodipine; Analysis of Variance; Antihypertensive Agents; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Female; Forearm; Hand Strength; Hemodynamics; Humans; Hypertension; Male; Middle Aged; Plethysmography; Tetrazoles; Valine; Valsartan; Vascular Resistance

2006
Effects of valsartan compared to amlodipine on preventing type 2 diabetes in high-risk hypertensive patients: the VALUE trial.
    Journal of hypertension, 2006, Volume: 24, Issue:7

    Topics: Aged; Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Risk Factors; Tetrazoles; Valine; Valsartan

2006
Randomized, double-blind, crossover comparison of amlodipine and valsartan in african-americans with hypertension using 24-hour ambulatory blood pressure monitoring.
    Pharmacotherapy, 2006, Volume: 26, Issue:7

    Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Black or African American; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypertension; Male; Tetrazoles; Valine; Valsartan

2006
Effects of amlodipine and valsartan on vascular damage and ambulatory blood pressure in untreated hypertensive patients.
    Journal of human hypertension, 2006, Volume: 20, Issue:10

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carotid Arteries; Endothelium, Vascular; Female; Humans; Hypertension; Male; Middle Aged; Pulse; Tetrazoles; Valine; Valsartan; Vascular Resistance

2006
The Valsartan Antihypertensive Long-Term Use Evaluation (VALUE) trial: outcomes in patients receiving monotherapy.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:3

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiac Output, Low; Diabetes Mellitus; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Incidence; Male; Middle Aged; Risk; Tetrazoles; Valine; Valsartan

2006
Targeting hypertension with valsartan: Lessons learned from the Valsartan/HCTZ versus Amlodipine in stage II hypertensive patients (VASt) trial.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2006, Volume: 7 Suppl 1

    Topics: Amlodipine; C-Reactive Protein; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Interleukin-6; Lipoproteins, LDL; Tetrazoles; Tissue Plasminogen Activator; Valine; Valsartan

2006
Outcomes in subgroups of hypertensive patients treated with regimens based on valsartan and amlodipine: An analysis of findings from the VALUE trial.
    Journal of hypertension, 2006, Volume: 24, Issue:11

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Female; Heart Arrest; Heart Failure; Humans; Hypertension; Male; Middle Aged; Proportional Hazards Models; Sex Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan

2006
Effects of amlodipine and valsartan on oxidative stress and plasma methylarginines in end-stage renal disease patients on hemodialysis.
    Kidney international, 2006, Volume: 70, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Arginine; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Female; Humans; Hypertension, Renal; Kidney Failure, Chronic; Male; Methylation; Middle Aged; Oxidative Stress; Renal Dialysis; Tetrazoles; Valine; Valsartan

2006
Effect of valsartan addition to amlodipine on ankle oedema and subcutaneous tissue pressure in hypertensive patients.
    Journal of human hypertension, 2007, Volume: 21, Issue:3

    Topics: Adult; Age Factors; Aged; Amlodipine; Ankle; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Edema; Female; Humans; Hypertension; Male; Middle Aged; Placebos; Prospective Studies; Single-Blind Method; Tetrazoles; Treatment Outcome; Valine; Valsartan

2007
Ambulatory blood pressure monitoring after 1 year on valsartan or amlodipine-based treatment: a VALUE substudy.
    Journal of hypertension, 2007, Volume: 25, Issue:3

    Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Denmark; Female; Heart Rate; Humans; Hypertension; Italy; Male; Middle Aged; Office Visits; Randomized Controlled Trials as Topic; Reproducibility of Results; Research; Risk Factors; Tetrazoles; United States; Valine; Valsartan

2007
Effects of valsartan or amlodipine alone or in combination on plasma catecholamine levels at rest and during standing in hypertensive patients.
    Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:3

    Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Catecholamines; Chromatography, High Pressure Liquid; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Posture; Rest; Tetrazoles; Treatment Outcome; Valine; Valsartan

2007
Reduction of microalbuminuria in patients with type 2 diabetes: the Shiga Microalbuminuria Reduction Trial (SMART).
    Diabetes care, 2007, Volume: 30, Issue:6

    Topics: Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Humans; Japan; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2007
Effect of antihypertensive agents on plasma adiponectin levels in hypertensive patients with metabolic syndrome.
    Nephrology (Carlton, Vic.), 2007, Volume: 12, Issue:2

    Topics: Adiponectin; Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Doxazosin; Female; Humans; Hypertension; Insulin Resistance; Lipids; Male; Metabolic Syndrome; Metoprolol; Middle Aged; Predictive Value of Tests; Prospective Studies; Ramipril; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan

2007
Tolerability and blood pressure-lowering efficacy of the combination of amlodipine plus valsartan compared with lisinopril plus hydrochlorothiazide in adult patients with stage 2 hypertension.
    Clinical therapeutics, 2007, Volume: 29, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Lisinopril; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2007
Amlodipine and valsartan combined and as monotherapy in stage 2, elderly, and black hypertensive patients: subgroup analyses of 2 randomized, placebo-controlled studies.
    Journal of clinical hypertension (Greenwich, Conn.), 2007, Volume: 9, Issue:5

    Topics: Age Factors; Aged; Amlodipine; Antihypertensive Agents; Black People; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Research Design; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan

2007
Two multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in combination and as monotherapy in adult patients with mild to moderate essential hyperten
    Clinical therapeutics, 2007, Volume: 29, Issue:4

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Edema; Female; Headache; Humans; Hypertension; Male; Middle Aged; Nasopharyngitis; Tetrazoles; Valine; Valsartan

2007
Vildagliptin, a novel dipeptidyl peptidase IV inhibitor, has no pharmacokinetic interactions with the antihypertensive agents amlodipine, valsartan, and ramipril in healthy subjects.
    Journal of clinical pharmacology, 2008, Volume: 48, Issue:1

    Topics: Adamantane; Administration, Oral; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Area Under Curve; Cross-Over Studies; Dipeptidyl-Peptidase IV Inhibitors; Drug Interactions; Female; Half-Life; Headache; Humans; Male; Middle Aged; Nausea; Nitriles; Pyrrolidines; Ramipril; Tablets; Tetrazoles; Valine; Valsartan; Vildagliptin

2008
Reduced incidence of new-onset atrial fibrillation with angiotensin II receptor blockade: the VALUE trial.
    Journal of hypertension, 2008, Volume: 26, Issue:3

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Atrial Fibrillation; Drug Therapy, Combination; Female; Humans; Hypertension; Incidence; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2008
Efficacy of the combination of amlodipine and valsartan in patients with hypertension uncontrolled with previous monotherapy: the Exforge in Failure after Single Therapy (EX-FAST) study.
    Journal of clinical hypertension (Greenwich, Conn.), 2008, Volume: 10, Issue:3

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Retreatment; Tetrazoles; Valine; Valsartan

2008
Comparative evaluation of effect of valsartan/amlodipine and atenolol/amlodipine combinations on atrial fibrillation recurrence in hypertensive patients with type 2 diabetes mellitus.
    Journal of cardiovascular pharmacology, 2008, Volume: 51, Issue:3

    Topics: Aged; Amlodipine; Anti-Arrhythmia Agents; Antihypertensive Agents; Atenolol; Atrial Fibrillation; Blood Pressure; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Electrocardiography; Female; Humans; Hypertension; Male; Middle Aged; Propafenone; Prospective Studies; Secondary Prevention; Tetrazoles; Valine; Valsartan

2008
Valsartan Amlodipine Randomized Trial (VART): design, methods, and preliminary results.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:1

    Topics: 3-Iodobenzylguanidine; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Data Interpretation, Statistical; Endpoint Determination; Female; Follow-Up Studies; Humans; Hypertension; Informed Consent; Male; Middle Aged; Patient Selection; Prospective Studies; Radionuclide Imaging; Radiopharmaceuticals; Research Design; Risk Factors; Sample Size; Tetrazoles; Ultrasonography; Valine; Valsartan

2008
Effects of valsartan or amlodipine on endothelial function and oxidative stress after one year follow-up in patients with essential hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2008, Volume: 30, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Asian People; Biomarkers; Blood Pressure; Brachial Artery; Calcium Channel Blockers; Deoxyguanosine; Dinoprost; Endothelium, Vascular; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Regional Blood Flow; Tetrazoles; Valine; Valsartan; Vasodilation

2008
Valsartan improves arterial stiffness in type 2 diabetes independently of blood pressure lowering.
    Hypertension (Dallas, Tex. : 1979), 2008, Volume: 51, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arteries; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2008
Effective and safe reduction of blood pressure with the combination of amlodipine 5 mg and valsartan 160 mg in hypertensive patients not controlled by calcium channel blocker monotherapy.
    Advances in therapy, 2008, Volume: 25, Issue:5

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2008
Predictors of new-onset diabetes mellitus in hypertensive patients: the VALUE trial.
    Journal of human hypertension, 2008, Volume: 22, Issue:8

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Glucose; Blood Pressure; Body Weight; Calcium Channel Blockers; Diabetes Mellitus; Double-Blind Method; Drug Therapy, Combination; Follow-Up Studies; Humans; Hypertension; Incidence; Middle Aged; Prognosis; Prospective Studies; Risk Factors; Tetrazoles; Time Factors; Valine; Valsartan

2008
Effect of valsartan and ramipril on atrial fibrillation recurrence and P-wave dispersion in hypertensive patients with recurrent symptomatic lone atrial fibrillation.
    American journal of hypertension, 2008, Volume: 21, Issue:9

    Topics: Aged; Amlodipine; Antihypertensive Agents; Atrial Fibrillation; Double-Blind Method; Electrocardiography; Female; Humans; Male; Peptide Fragments; Procollagen; Ramipril; Recurrence; Tetrazoles; Valine; Valsartan

2008
Progressive effects of valsartan compared with amlodipine in prevention of diabetes according to categories of diabetogenic risk in hypertensive patients: the VALUE trial.
    Blood pressure, 2008, Volume: 17, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Follow-Up Studies; Humans; Hypertension; Middle Aged; Multivariate Analysis; Regression Analysis; Risk Factors; Tetrazoles; Treatment Outcome; Valine; Valsartan

2008
Impact of renin-angiotensin system inhibition on microalbuminuria in type 2 diabetes: a post hoc analysis of the Shiga Microalbuminuria Reduction Trial (SMART).
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:6

    Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Creatinine; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan

2008
Effect of valsartan addition to amlodipine on insulin sensitivity in overweight-obese hypertensive patients.
    Internal medicine (Tokyo, Japan), 2008, Volume: 47, Issue:21

    Topics: Adult; Aged; Amlodipine; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Insulin; Male; Middle Aged; Obesity; Overweight; Prospective Studies; Tetrazoles; Valine; Valsartan

2008
[Economics of nephroprotection in arterial hypertension and type 2 diabetes mellitus].
    Kardiologiia, 2008, Volume: 48, Issue:12

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biphenyl Compounds; Cost-Benefit Analysis; Diabetes Mellitus, Type 2; Drug Costs; Humans; Hypertension; Irbesartan; Kidney Diseases; Tetrazoles; Valine; Valsartan

2008
Efficacy and tolerability of amlodipine/valsartan combination therapy in hypertensive patients not adequately controlled on valsartan monotherapy.
    Current medical research and opinion, 2009, Volume: 25, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Single-Blind Method; Tetrazoles; Valine; Valsartan

2009
Efficacy and safety of the single pill combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not controlled by amlodipine 10 mg plus olmesartan 20 mg in free combination.
    Current medical research and opinion, 2009, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Cohort Studies; Drug Combinations; Female; Humans; Hypertension; Imidazoles; Male; Middle Aged; Patient Compliance; Prospective Studies; Tetrazoles; Valine; Valsartan

2009
The combination of amlodipine/valsartan 5/160 mg produces less peripheral oedema than amlodipine 10 mg in hypertensive patients not adequately controlled with amlodipine 5 mg.
    International journal of clinical practice, 2009, Volume: 63, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Edema; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2009
Combination of amlodipine 10 mg and valsartan 160 mg lowers blood pressure in patients with hypertension not controlled by an ACE inhibitor/CCB combination.
    Blood pressure. Supplement, 2008, Volume: 2

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Resistance; Drug Therapy, Combination; Felodipine; Female; Humans; Hypertension; Male; Middle Aged; Ramipril; Tetrazoles; Treatment Outcome; Valine; Valsartan

2008
Long-term tolerability and efficacy of the combination of amlodipine/valsartan in hypertensive patients: a 54-week, open-label extension study.
    Current medical research and opinion, 2009, Volume: 25, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Placebos; Tetrazoles; Valine; Valsartan

2009
Add-on benefits of amlodipine and thiazide in nondiabetic chronic kidney disease stage 1/2 patients treated with valsartan.
    Kidney & blood pressure research, 2009, Volume: 32, Issue:1

    Topics: Adult; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Carotid Arteries; Diuretics; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Renal Insufficiency, Chronic; Tetrazoles; Thiazides; Valine; Valsartan

2009
Effects of force-titrated valsartan/hydrochlorothiazide versus amlodipine/hydrochlorothiazide on ambulatory blood pressure in patients with stage 2 hypertension: the EVALUATE study.
    Blood pressure monitoring, 2009, Volume: 14, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2009
Triple antihypertensive therapy with amlodipine, valsartan, and hydrochlorothiazide: a randomized clinical trial.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:1

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Single-Blind Method; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan

2009
Efficacy and tolerability of amlodipine/valsartan combination therapy in hypertensive patients not adequately controlled on amlodipine monotherapy.
    Current medical research and opinion, 2009, Volume: 25, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Algorithms; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Placebos; Tetrazoles; Treatment Failure; Treatment Outcome; Valine; Valsartan

2009
Randomized study to compare valsartan +/- HCTZ versus amlodipine +/- HCTZ strategies to maximize blood pressure control.
    Vascular health and risk management, 2009, Volume: 5

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Double-Blind Method; Drug Therapy, Combination; Europe; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; South America; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan

2009
Amlodipine/valsartan/hydrochlorothiazide triple combination therapy in moderate/severe hypertension: Secondary analyses evaluating efficacy and safety.
    Advances in therapy, 2009, Volume: 26, Issue:11

    Topics: Adolescent; Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Tetrazoles; Valine; Valsartan

2009
[Efficacy and safety of the single pill combination of valsartan 80 mg plus amlodipine 5 mg in mild to moderate essential hypertensive patients without adequate blood pressure control by monotherapy].
    Zhonghua xin xue guan bing za zhi, 2009, Volume: 37, Issue:9

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2009
Effect of valsartan or olmesartan addition to amlodipine on ankle edema in hypertensive patients.
    Advances in therapy, 2010, Volume: 27, Issue:1

    Topics: Adult; Aged; Amlodipine; Ankle Joint; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Edema; Female; Heart Rate; Humans; Hypertension; Imidazoles; Male; Middle Aged; Norepinephrine; Prospective Studies; Tetrazoles; Valine; Valsartan

2010
Valsartan addition to amlodipine is more effective than losartan addition in hypertensive patients inadequately controlled by amlodipine.
    Vascular health and risk management, 2010, Mar-03, Volume: 6

    Topics: Adult; Aged; Amlodipine; Anthracenes; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan

2010
Amlodipine-valsartan combination decreases central systolic blood pressure more effectively than the amlodipine-atenolol combination: the EXPLOR study.
    Hypertension (Dallas, Tex. : 1979), 2010, Volume: 55, Issue:6

    Topics: Administration, Oral; Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Probability; Prospective Studies; Severity of Illness Index; Single-Blind Method; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult

2010
Rationale and design of the NAGOYA HEART Study: comparison between valsartan and amlodipine regarding morbidity and mortality in patients with hypertension and glucose intolerance.
    Journal of cardiology, 2010, Volume: 56, Issue:1

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Complications; Humans; Hypertension; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan

2010
Combined therapy with renin-angiotensin system and calcium channel blockers in type 2 diabetic hypertensive patients with proteinuria: effects on soluble TWEAK, PTX3, and flow-mediated dilation.
    Clinical journal of the American Society of Nephrology : CJASN, 2010, Volume: 5, Issue:7

    Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; C-Reactive Protein; Calcium Channel Blockers; Chi-Square Distribution; Cytokine TWEAK; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Renin-Angiotensin System; Serum Amyloid P-Component; Tetrazoles; Time Factors; Treatment Outcome; Tumor Necrosis Factors; Turkey; Valine; Valsartan; Vasodilation

2010
Efficacy and safety of a single-pill combination of amlodipine/valsartan in Asian hypertensive patients inadequately controlled with amlodipine monotherapy.
    Current medical research and opinion, 2010, Volume: 26, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Algorithms; Amlodipine; Antihypertensive Agents; Asian People; Double-Blind Method; Drug Combinations; Drug Resistance; Female; Humans; Hypertension; Male; Middle Aged; Tablets; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult

2010
Angiotensin receptor blocker/diuretic combination preserves insulin responses in obese hypertensives.
    Journal of hypertension, 2010, Volume: 28, Issue:8

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Glucose; Blood Pressure; Body Mass Index; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Female; Glucose Tolerance Test; Humans; Hydrochlorothiazide; Hypertension; Insulin; Male; Middle Aged; Obesity; Tetrazoles; Treatment Outcome; Valine; Valsartan

2010
Chronotherapy with valsartan/amlodipine fixed combination: improved blood pressure control of essential hypertension with bedtime dosing.
    Chronobiology international, 2010, Volume: 27, Issue:6

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Drug Chronotherapy; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Sleep; Tetrazoles; Valine; Valsartan

2010
Time to achieve blood pressure goal with a combination versus a conventional monotherapy approach in hypertensive patients with metabolic syndrome.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2010, Volume: 32, Issue:5

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Comorbidity; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Metabolic Syndrome; Middle Aged; Prospective Studies; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan

2010
Angiotensin II receptor blockade with valsartan decreases plasma osteopontin levels in patients with essential hypertension.
    Journal of human hypertension, 2011, Volume: 25, Issue:5

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; C-Reactive Protein; Female; Humans; Hypertension; Male; Middle Aged; Osteopontin; Tetrazoles; Valine; Valsartan

2011
Evaluation of pharmacokinetic interactions between amlodipine, valsartan, and hydrochlorothiazide in patients with hypertension.
    Journal of clinical pharmacology, 2011, Volume: 51, Issue:6

    Topics: Adolescent; Adult; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2011
Triple combination therapy with amlodipine, valsartan, and hydrochlorothiazide vs dual combination therapy with amlodipine and hydrochlorothiazide for stage 2 hypertensive patients.
    Vascular health and risk management, 2010, Sep-07, Volume: 6

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2010
Effects of valsartan and amlodipine on cardiorenal protection in Japanese hypertensive patients: the Valsartan Amlodipine Randomized Trial.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Blood Pressure; Cardiovascular Diseases; Female; Humans; Hypertension; Kidney Diseases; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2011
Moderate versus intensive treatment of hypertension with amlodipine/valsartan for patients uncontrolled on angiotensin receptor blocker monotherapy.
    Journal of hypertension, 2011, Volume: 29, Issue:1

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Tetrazoles; Valine; Valsartan

2011
24-Hour ambulatory blood pressure response to combination valsartan/hydrochlorothiazide and amlodipine/hydrochlorothiazide in stage 2 hypertension by ethnicity: the EVALUATE study.
    Journal of clinical hypertension (Greenwich, Conn.), 2010, Volume: 12, Issue:11

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Ethnicity; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Racial Groups; Regression Analysis; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan

2010
Real-life safety and effectiveness of amlodipine/valsartan combination in the treatment of hypertension.
    Advances in therapy, 2011, Volume: 28, Issue:2

    Topics: Administration, Oral; Amlodipine; Antihypertensive Agents; Bangladesh; Blood Pressure; Blood Pressure Monitoring, Ambulatory; China; Dose-Response Relationship, Drug; Drug Combinations; Drug Synergism; Egypt; Female; Heart Rate; Humans; Hypertension; Malaysia; Male; Middle Aged; Pakistan; Product Surveillance, Postmarketing; Russia; Severity of Illness Index; Tetrazoles; Treatment Outcome; Valine; Valsartan

2011
24-Hour ambulatory blood pressure control with triple-therapy amlodipine, valsartan and hydrochlorothiazide in patients with moderate to severe hypertension.
    Journal of human hypertension, 2011, Volume: 25, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2011
Beneficial cardiometabolic actions of telmisartan plus amlodipine therapy in elderly patients with poorly controlled hypertension.
    Clinical cardiology, 2011, Volume: 34, Issue:4

    Topics: Adiponectin; Age Factors; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Drug Substitution; Drug Therapy, Combination; Female; Humans; Hypertension; Japan; Male; Prospective Studies; Telmisartan; Tetrazoles; Time Factors; Treatment Outcome; Up-Regulation; Valine; Valsartan

2011
Efficacy and tolerability of a single-pill combination of amlodipine/valsartan in Asian hypertensive patients not adequately controlled with valsartan monotherapy.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2011, Volume: 33, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asian People; Calcium Channel Blockers; China; Double-Blind Method; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Hypertension; Korea; Male; Middle Aged; Tetrazoles; Thailand; Treatment Outcome; Valine; Valsartan; Young Adult

2011
Rationale and design of the Newer Versus Older Antihypertensive Agents in African Hypertensive Patients (NOAAH) trial.
    Blood pressure, 2011, Volume: 20, Issue:5

    Topics: Adult; Africa South of the Sahara; Aged; Amlodipine; Antihypertensive Agents; Bisoprolol; Black People; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diuretics; Drug Combinations; Female; Humans; Hydralazine; Hydrochlorothiazide; Hypertension; Male; Methyldopa; Middle Aged; Research Design; Risk Factors; Tetrazoles; Valine; Valsartan

2011
[The Shiga Microalbuminuria Reduction Trial].
    Nihon rinsho. Japanese journal of clinical medicine, 2010, Volume: 68 Suppl 9

    Topics: Albuminuria; Amlodipine; Animals; Antihypertensive Agents; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Middle Aged; Prospective Studies; Rats; Tetrazoles; Valine; Valsartan

2010
Combination angiotensin-receptor blocker (ARB)/calcium channel blocker with HCTZ vs the maximal recommended dose of an ARB with HCTZ in patients with stage 2 hypertension: the exforge as compared to losartan treatment in stage 2 systolic hypertension (EXA
    Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:8

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; United States; Valine; Valsartan

2011
[Efficacy of fixed combination amlodipine/valsartan in hospitalized patients with hypertensive disease].
    Kardiologiia, 2011, Volume: 51, Issue:7

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Drug Monitoring; Drug Synergism; Female; Humans; Hypertension; Inpatients; Male; Medication Adherence; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2011
Office and ambulatory blood pressure-lowering effects of combination valsartan/hydrochlorothiazide vs. hydrochlorothiazide-based therapy in obese, hypertensive patients.
    Journal of clinical hypertension (Greenwich, Conn.), 2011, Volume: 13, Issue:10

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Comorbidity; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Obesity; Office Visits; Tetrazoles; Treatment Outcome; Valine; Valsartan

2011
Effects of valsartan and amlodipine on home blood pressure and cardiovascular events in Japanese hypertensive patients: a subanalysis of the VART.
    Journal of human hypertension, 2012, Volume: 26, Issue:11

    Topics: Aged; Albuminuria; Amlodipine; Angina Pectoris; Antihypertensive Agents; Asian People; Blood Pressure; Cardiovascular Diseases; Cause of Death; Creatinine; Death, Sudden; Female; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Male; Middle Aged; Myocardial Infarction; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan

2012
Distinct effects of fixed combinations of valsartan with either amlodipine or hydrochlorothiazide on lipoprotein subfraction profile in patients with hypertension.
    Journal of human hypertension, 2013, Volume: 27, Issue:1

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Cholesterol; Female; Humans; Hydrochlorothiazide; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Particle Size; Tetrazoles; Triglycerides; Valine; Valsartan

2013
Comparing antihypertensive effect and plasma ciclosporin concentration between amlodipine and valsartan regimens in hypertensive renal transplant patients receiving ciclosporin therapy.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2011, Dec-01, Volume: 11, Issue:6

    Topics: Adult; Amlodipine; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Pressure; Cyclosporine; Cytochrome P-450 CYP3A; Double-Blind Method; Drug Interactions; Female; Genotype; Humans; Hypertension; Immunosuppressive Agents; Kidney Transplantation; Male; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Prospective Studies; Tetrazoles; Valine; Valsartan

2011
Ambulatory blood pressure response to triple therapy with an angiotensin-receptor blocker (ARB), calcium-channel blocker (CCB), and HCTZ versus dual therapy with an ARB and HCTZ.
    Vascular health and risk management, 2011, Volume: 7

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2011
Comparison between valsartan and amlodipine regarding cardiovascular morbidity and mortality in hypertensive patients with glucose intolerance: NAGOYA HEART Study.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 59, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Blood Glucose; Blood Pressure; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glucose Intolerance; Glycated Hemoglobin; Humans; Hypertension; Japan; Male; Middle Aged; Morbidity; Prospective Studies; Risk Factors; Survival Rate; Tetrazoles; Valine; Valsartan

2012
Antihypertensive and metabolic effects of Angiotensin receptor blocker/diuretic combination therapy in obese, hypertensive African American and white patients.
    American journal of therapeutics, 2013, Volume: 20, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Black or African American; Blood Glucose; Diuretics; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hyperglycemia; Hypertension; Insulin; Intention to Treat Analysis; Male; Middle Aged; Obesity, Abdominal; Prediabetic State; Tetrazoles; Treatment Outcome; Valine; Valsartan; White People

2013
Effects of valsartan versus olmesartan addition to amlodipine/hydrochlorothiazide combination in treating stage 2 hypertensive patients.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:5

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2012
[Effects of valsartan combined with amlodipine or hydrochlorothiazide regimen on blood pressure variation in elderly hypertensive patients].
    Zhonghua xin xue guan bing za zhi, 2012, Volume: 40, Issue:1

    Topics: Aged; Amlodipine; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2012
Effects of valsartan or ramipril addition to amlodipine/hydrochlorothiazide combination on left ventricular mass in diabetic hypertensive patients with left ventricular hypertrophy.
    Expert opinion on pharmacotherapy, 2012, Volume: 13, Issue:8

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Male; Middle Aged; Ramipril; Tetrazoles; Valine; Valsartan

2012
Effects of exercise therapy alone and in combination with a calcium channel blocker or an angiotensin receptor blocker in hypertensive patients.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:7

    Topics: Adult; Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Therapy, Combination; Exercise Therapy; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2012
Amlodipine/valsartan 5/160 mg versus valsartan 160 mg in Chinese hypertensives.
    International journal of cardiology, 2013, Sep-01, Volume: 167, Issue:5

    Topics: Adult; Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Asian People; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2013
Comparison of the efficacy and safety profiles of two fixed-dose combinations of antihypertensive agents, amlodipine/benazepril versus valsartan/hydrochlorothiazide, in patients with type 2 diabetes mellitus and hypertension: a 16-week, multicenter, rando
    Clinical therapeutics, 2012, Volume: 34, Issue:8

    Topics: Aged; Albuminuria; Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Drug Combinations; Female; Glycated Hemoglobin; Humans; Hydrochlorothiazide; Hypertension; Lipids; Male; Middle Aged; Prospective Studies; Taiwan; Tetrazoles; Time Factors; Treatment Outcome; Uric Acid; Valine; Valsartan

2012
Post-marketing surveillance study of valsartan/amlodipine combination in Taiwanese hypertensive patients.
    Blood pressure, 2012, Volume: 21 Suppl 1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Blood Pressure; Female; Humans; Hypertension; Male; Middle Aged; Product Surveillance, Postmarketing; Prospective Studies; Taiwan; Tetrazoles; Time Factors; Valine; Valsartan

2012
Cardiovascular outcomes in hypertensive patients: comparing single-agent therapy with combination therapy.
    Journal of hypertension, 2012, Volume: 30, Issue:11

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Kaplan-Meier Estimate; Male; Middle Aged; Myocardial Infarction; Prognosis; Retrospective Studies; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan

2012
Changes in aortic pulse wave velocity in hypertensive postmenopausal women: comparison between a calcium channel blocker vs angiotensin receptor blocker regimen.
    Journal of clinical hypertension (Greenwich, Conn.), 2012, Volume: 14, Issue:11

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Postmenopause; Pulse Wave Analysis; Tetrazoles; Valine; Valsartan; Vascular Stiffness

2012
The comparative effects of valsartan and amlodipine on vascular microinflammation in newly diagnosed hypertensive patients.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2013, Volume: 35, Issue:6

    Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Calcium Channel Blockers; Female; Humans; Hypertension; Inflammation Mediators; Male; Middle Aged; Prospective Studies; Risk Factors; Serum Amyloid P-Component; Tetrazoles; Valine; Valsartan; Vasculitis

2013
An additional LDL-lowering effect of amlodipine; not only an antihypertensive?
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2013, Volume: 35, Issue:6

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Cholesterol; Dyslipidemias; Essential Hypertension; Female; Humans; Hypertension; Lipoproteins, HDL; Lipoproteins, LDL; Male; Middle Aged; Tetrazoles; Triglycerides; Valine; Valsartan

2013
The comparative effects of valsartan and amlodipine on vWf levels and N/L ratio in patients with newly diagnosed hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2013, Volume: 35, Issue:7

    Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Essential Hypertension; Female; Humans; Hypertension; Leukocyte Count; Lymphocytes; Male; Middle Aged; Neutrophils; Prospective Studies; Tetrazoles; Valine; Valsartan; von Willebrand Factor

2013
Amlodipine seems to be superior to valsartan in decreasing microalbuminuria in newly diagnosed hypertensive patients: a novel effect to be explained with hyperfiltration?
    Renal failure, 2013, Volume: 35, Issue:3

    Topics: Adult; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan

2013
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate.
    Blood pressure, 2013, Volume: 22 Suppl 1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan

2013
Effects of CPAP on "vascular" risk factors in patients with obstructive sleep apnea and arterial hypertension.
    Vascular health and risk management, 2013, Volume: 9

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Arterial Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Continuous Positive Airway Pressure; Diuretics; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Manometry; Middle Aged; Polysomnography; Predictive Value of Tests; Pulse Wave Analysis; Risk Factors; Russia; Severity of Illness Index; Sleep Apnea, Obstructive; Tetrazoles; Treatment Outcome; Valine; Valsartan; Vascular Stiffness

2013
Effects of demographics on the antihypertensive efficacy of triple therapy with amlodipine, valsartan, and hydrochlorothiazide for moderate to severe hypertension.
    Current medical research and opinion, 2013, Volume: 29, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Demography; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Valine; Valsartan; Young Adult

2013
Efficacy of newer versus older antihypertensive drugs in black patients living in sub-Saharan Africa.
    Journal of human hypertension, 2013, Volume: 27, Issue:12

    Topics: Adult; Africa South of the Sahara; Amlodipine; Antihypertensive Agents; Bisoprolol; Black People; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2013
Pharmacokinetic comparison of 2 fixed-dose combination tablets of amlodipine and valsartan in healthy male Korean volunteers: a randomized, open-label, 2-period, single-dose, crossover study.
    Clinical therapeutics, 2013, Volume: 35, Issue:7

    Topics: Administration, Oral; Adult; Amlodipine; Asian People; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Healthy Volunteers; Humans; Male; Middle Aged; Tablets; Tetrazoles; Valine; Valsartan; Young Adult

2013
Efficacy and safety of valsartan and amlodipine single-pill combination in hypertensive patients (PEAK study).
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2013, Volume: 41, Issue:5

    Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Patient Compliance; Tetrazoles; Treatment Outcome; Turkey; Valine; Valsartan

2013
Effect of renin-angiotensin system blockade on soluble Klotho in patients with type 2 diabetes, systolic hypertension, and albuminuria.
    Clinical journal of the American Society of Nephrology : CJASN, 2013, Volume: 8, Issue:11

    Topics: Aged; Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diuretics; Female; Glucuronidase; Hospitals, University; Humans; Hydrochlorothiazide; Hypertension; Klotho Proteins; London; Male; Middle Aged; Phosphates; Pulse Wave Analysis; Renin-Angiotensin System; Systole; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan

2013
Effects of valsartan versus amlodipine in diabetic hypertensive patients with or without previous cardiovascular disease.
    The American journal of cardiology, 2013, Dec-01, Volume: 112, Issue:11

    Topics: Aged; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Case-Control Studies; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Female; Heart Failure; Hospitalization; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Proportional Hazards Models; Stroke; Tetrazoles; Treatment Outcome; Valine; Valsartan

2013
Comparative effects of telmisartan and valsartan as add-on agents for hypertensive patients with morning blood pressure insufficiently controlled by amlodipine monotherapy.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2014, Volume: 37, Issue:3

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Chemical Analysis; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Endpoint Determination; Female; Heart Rate; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Sleep; Telmisartan; Tetrazoles; Valine; Valsartan

2014
[The influence of citoflavin on molecular mechanisms of hypertensive encephalopathy development in patients with systolic arterial hypertension].
    Eksperimental'naia i klinicheskaia farmakologiia, 2014, Volume: 77, Issue:6

    Topics: Aged; Aged, 80 and over; Amlodipine; Aspirin; Atorvastatin; Blood Pressure; Blood Proteins; Drug Combinations; Drug Therapy, Combination; Echocardiography; Female; Flavin Mononucleotide; Hemodynamics; Heptanoic Acids; Humans; Hypertension; Hypertensive Encephalopathy; Inosine Diphosphate; Male; Neuroprotective Agents; Niacinamide; Pyrroles; Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Succinates; Systole; Tetrazoles; Valine; Valsartan

2014
[Optimization of arterial hypertension management by the use of two- and three-drugs fixed dose combinations at the daily stay department].
    Kardiologiia, 2014, Volume: 54, Issue:7

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Day Care, Medical; Dose-Response Relationship, Drug; Drug Combinations; Drug Monitoring; Drug Synergism; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Valine; Valsartan

2014
Aortic remodelling following the treatment and regression of hypertensive left ventricular hypertrophy: a cardiovascular magnetic resonance study.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2015, Volume: 37, Issue:4

    Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Aorta, Thoracic; Bendroflumethiazide; Dose-Response Relationship, Drug; Drug Therapy, Combination; Essential Hypertension; Female; Follow-Up Studies; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Magnetic Resonance Imaging, Cine; Male; Middle Aged; Sympatholytics; Treatment Outcome; Valsartan; Vascular Remodeling; Vascular Stiffness

2015
Evening versus morning dosing of antihypertensive drugs in hypertensive patients with sleep apnoea: a cross-over study.
    Journal of hypertension, 2015, Volume: 33, Issue:2

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Continuous Positive Airway Pressure; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Prospective Studies; Sleep Apnea, Obstructive; Valsartan

2015
Comparison of single-pill strategies first line in hypertension: perindopril/amlodipine versus valsartan/amlodipine.
    Journal of hypertension, 2015, Volume: 33, Issue:2

    Topics: Adult; Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Indapamide; Male; Middle Aged; Perindopril; Valsartan

2015
Endocan, a novel marker of endothelial dysfunction in patients with essential hypertension: comparative effects of amlodipine and valsartan.
    Blood pressure, 2015, Volume: 24, Issue:1

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; C-Reactive Protein; Endothelium, Vascular; Essential Hypertension; Female; Humans; Hypertension; Male; Middle Aged; Neoplasm Proteins; Proteoglycans; Tetrazoles; Valine; Valsartan

2015
Assessment of glomerular filtration rate based on alterations of serum brain-derived neurotrophic factor in type 2 diabetic subjects treated with amlodipine/benazepril or valsartan/hydrochlorothiazide.
    Disease markers, 2015, Volume: 2015

    Topics: Aged; Amlodipine; Antihypertensive Agents; Benzazepines; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Humans; Hydrochlorothiazide; Male; Middle Aged; Valsartan

2015
Choice of Antihypertensive Combination Therapy Based on Daily Salt Intake.
    The American journal of the medical sciences, 2015, Volume: 350, Issue:3

    Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Diuretics; Drug Combinations; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Male; Metabolic Syndrome; Middle Aged; Potassium; Prospective Studies; Sodium; Sodium Chloride, Dietary; Tetrazoles; Treatment Outcome; Valine; Valsartan

2015
Efficacy and safety of two single-pill fixed-dose combinations of angiotensin II receptor blockers/calcium channel blockers in hypertensive patients (EXAMINER study).
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2016, Volume: 38, Issue:1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Drug Monitoring; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Tetrazoles; Treatment Outcome; Triglycerides; Uric Acid; Valsartan

2016
No evidence for a J-shaped curve in treated hypertensive patients with increased cardiovascular risk: The VALUE trial.
    Blood pressure, 2016, Volume: 25, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Coronary Artery Disease; Diastole; Double-Blind Method; Female; Humans; Hypertension; Male; Middle Aged; Myocardial Infarction; Prognosis; Proportional Hazards Models; Prospective Studies; Risk Factors; Stroke; Systole; Treatment Outcome; Valsartan

2016
Predictors of cardiac morbidity in diabetic, new-onset diabetic and non-diabetic high-risk hypertensive patients: The Valsartan Antihypertensive Long-term Use Evaluation (VALUE) trial.
    Blood pressure, 2016, Volume: 25, Issue:4

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Complications; Female; Heart Failure; Hospitalization; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Risk Factors; Valsartan

2016
The Effects of Valsartan and Amlodipine on the Levels of Irisin, Adropin, and Perilipin.
    Clinical laboratory, 2015, Volume: 61, Issue:12

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Proteins; Calcium; Carrier Proteins; Female; Fibronectins; Humans; Hypertension; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Obesity; Peptides; Perilipin-1; Phosphoproteins; Valsartan

2015
Pharmacokinetic drug-drug interaction assessment between LCZ696, an angiotensin receptor neprilysin inhibitor, and hydrochlorothiazide, amlodipine, or carvedilol.
    Clinical pharmacology in drug development, 2015, Volume: 4, Issue:6

    Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Area Under Curve; Arizona; Biphenyl Compounds; Calcium Channel Blockers; Carbazoles; Carvedilol; Cross-Over Studies; Diuretics; Drug Administration Schedule; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Healthy Volunteers; Humans; Hydrochlorothiazide; Male; Metabolic Clearance Rate; Middle Aged; Models, Biological; Neprilysin; Propanolamines; Protease Inhibitors; Tetrazoles; Valsartan

2015
Efficacy and safety of sacubitril/valsartan (LCZ696) add-on to amlodipine in Asian patients with systolic hypertension uncontrolled with amlodipine monotherapy.
    Journal of hypertension, 2017, Volume: 35, Issue:4

    Topics: Aged; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Asian People; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Systole; Tetrazoles; Treatment Outcome; Valsartan

2017
Effects of Amlodipine and Valsartan on Blood Pressure Variability and Pulse Wave Velocity in Hypertensive Patients.
    The American journal of the medical sciences, 2017, Volume: 353, Issue:1

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypertension; Male; Middle Aged; Pulse Wave Analysis; Valsartan

2017
Effects of valsartan and amlodipine on oxidative stress in type 2 diabetic patients with hypertension: a randomized, multicenter study.
    The Korean journal of internal medicine, 2017, Volume: 32, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Valsartan

2017
Effect of Sacubitril/Valsartan on Exercise-Induced Lipid Metabolism in Patients With Obesity and Hypertension.
    Hypertension (Dallas, Tex. : 1979), 2018, Volume: 71, Issue:1

    Topics: Adipose Tissue; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Combinations; Drug Monitoring; Exercise; Female; Humans; Hypertension; Lipid Metabolism; Male; Middle Aged; Natriuretic Peptides; Neprilysin; Obesity, Abdominal; Tetrazoles; Treatment Outcome; Valsartan

2018
The effects of angiotensin receptor neprilysin inhibition by sacubitril/valsartan on adipose tissue transcriptome and protein expression in obese hypertensive patients.
    Scientific reports, 2018, 03-02, Volume: 8, Issue:1

    Topics: Adipose Tissue; Adult; Aminobutyrates; Amlodipine; Angiotensin Receptor Antagonists; Biphenyl Compounds; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Neprilysin; Obesity; Proteins; Subcutaneous Fat; Tetrazoles; Transcriptome; Valsartan

2018
Pharmacokinetic Drug Interactions Between Amlodipine, Valsartan, and Rosuvastatin in Healthy Volunteers.
    Advances in therapy, 2019, Volume: 36, Issue:7

    Topics: Adult; Amlodipine; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Interactions; Drug Monitoring; Healthy Volunteers; Humans; Hypertension; Male; Middle Aged; Rosuvastatin Calcium; Valsartan

2019
Efficacy of a new single-pill combination of a thiazide-like diuretic and a calcium channel blocker (indapamide sustained release/amlodipine) in essential hypertension.
    Journal of hypertension, 2019, Volume: 37, Issue:11

    Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Delayed-Action Preparations; Diuretics; Double-Blind Method; Drug Combinations; Essential Hypertension; Female; Humans; Indapamide; Male; Middle Aged; Thiazides; Valsartan

2019
Pharmacokinetic and Safety Profiles of a Fixed-Dose Combination of Amlodipine, Valsartan, and Atorvastatin: A 3-Period Replicate Crossover Study.
    Clinical pharmacology in drug development, 2020, Volume: 9, Issue:3

    Topics: Adult; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Area Under Curve; Atorvastatin; Cross-Over Studies; Drug Combinations; Humans; Male; Therapeutic Equivalency; Valsartan; Young Adult

2020
Circulating microparticles and central blood pressure according to antihypertensive strategy.
    Clinics (Sao Paulo, Brazil), 2019, Volume: 74

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Cell-Derived Microparticles; Drug Therapy, Combination; Female; Flow Cytometry; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Rosuvastatin Calcium; Valsartan

2019
Genetic factors associated with elevation of uric acid after treatment with thiazide-like diuretic in patients with essential hypertension.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2020, Volume: 43, Issue:3

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Essential Hypertension; Female; Genome-Wide Association Study; Humans; Indapamide; Male; Middle Aged; Polymorphism, Single Nucleotide; Uric Acid; Valsartan

2020
Blood Pressure-Lowering Profiles and Clinical Effects of Angiotensin Receptor Blockers Versus Calcium Channel Blockers.
    Hypertension (Dallas, Tex. : 1979), 2020, Volume: 75, Issue:6

    Topics: Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Blood Pressure Determination; Calcium Channel Blockers; Female; Heart Failure; Humans; Hypotension; Male; Middle Aged; Myocardial Infarction; Outcome and Process Assessment, Health Care; Risk Assessment; Stroke; Time; Valsartan

2020
Valsartan Versus Amlodipine Effect on Left Ventricular Multidirectional Deformation and Adipocytokines Levels in Hypertensive Patients: Speckle Tracking Echocardiography.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2020, Volume: 27, Issue:5

    Topics: Adipokines; Adiponectin; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; C-Reactive Protein; Calcium Channel Blockers; Echocardiography; Egypt; Female; Humans; Hypertension; Leptin; Male; Middle Aged; Predictive Value of Tests; Time Factors; Treatment Outcome; Tumor Necrosis Factor-alpha; Valsartan; Ventricular Function, Left; Ventricular Remodeling

2020
Amlodipine/valsartan fixed-dose combination treatment in the management of hypertension: A double-blind, randomized trial.
    Journal of the Chinese Medical Association : JCMA, 2020, Volume: 83, Issue:10

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Valsartan

2020
Effects of the valsartan/amlodipine combination and nifedipine gastrointestinal therapeutic system monotherapy on brachial pulse pressure and radial augmentation index in hypertensive patients.
    Blood pressure monitoring, 2021, Aug-01, Volume: 26, Issue:4

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Nifedipine; Tetrazoles; Treatment Outcome; Valsartan

2021
Efficacy and safety of Tengfu Jiangya tablet combined with valsartan/amlodipine in the treatment of stage 2 hypertension: study protocol for a randomized controlled trial.
    Trials, 2022, Feb-22, Volume: 23, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Drugs, Chinese Herbal; Humans; Hypertension; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Tablets; Valsartan

2022

Other Studies

114 other study(ies) available for valsartan and amlodipine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7

    Topics: Glutathione; Pharmacology; Sulfur Radioisotopes

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Disparate effects of angiotensin II antagonists and calcium channel blockers on albuminuria in experimental diabetes and hypertension: potential role of nephrin.
    Journal of hypertension, 2003, Volume: 21, Issue:1

    Topics: Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Drug Therapy, Combination; Hypertension; Kidney Glomerulus; Male; Membrane Proteins; Proteins; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sclerosis; Systole; Tetrazoles; Valine; Valsartan; Verapamil

2003
The role of nitric oxide in the regulation of glomerular haemodynamics in humans.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2004, Volume: 19, Issue:6

    Topics: Adult; Amlodipine; Angiotensin Receptor Antagonists; Calcium Channel Blockers; Glomerular Filtration Rate; Hemodynamics; Humans; Kidney Glomerulus; Middle Aged; Nitric Oxide; Tetrazoles; Valine; Valsartan; Vasodilator Agents

2004
Valsartan treatment of hypertension--does VALUE add value?
    Lancet (London, England), 2004, Jun-19, Volume: 363, Issue:9426

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Endpoint Determination; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan

2004
Blood pressure dependent and independent effects of antihypertensive treatment on clinical events in the VALUE Trial.
    Lancet (London, England), 2004, Jun-19, Volume: 363, Issue:9426

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan

2004
Effects of the angiotensin-1 receptor blocker valsartan compared with amlodipine on renal hemodynamics.
    American journal of hypertension, 2004, Volume: 17, Issue:7

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Glomerular Filtration Rate; Humans; Hypertension; Microcirculation; Receptor, Angiotensin, Type 1; Renal Circulation; Tetrazoles; Treatment Outcome; Valine; Valsartan

2004
[The value of VALUE--a hypertension study which compared valsartan with amlodipine. New data support early, optimal blood pressure control for high-risk patients].
    Lakartidningen, 2004, Jul-22, Volume: 101, Issue:30-31

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Risk Factors; Tetrazoles; Valine; Valsartan

2004
[Preventing end-organ damage in hypertension. What is the significance of the VALUE Study for general practice?].
    MMW Fortschritte der Medizin, 2004, Jul-08, Volume: 146, Issue:27-28

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Cardiovascular Diseases; Cause of Death; Humans; Hypertension; Myocardial Infarction; Randomized Controlled Trials as Topic; Survival Rate; Tetrazoles; Valine; Valsartan

2004
[Type 2 diabetic patient with kidney damage. Sartans banish dialysis risk].
    MMW Fortschritte der Medizin, 2004, Jul-08, Volume: 146, Issue:27-28

    Topics: Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Kidney Failure, Chronic; Randomized Controlled Trials as Topic; Renal Dialysis; Tetrazoles; Valine; Valsartan

2004
VALUE in hypertension treatment.
    Current hypertension reports, 2004, Volume: 6, Issue:6

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Cardiovascular Diseases; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan

2004
[AT1 blocker or calcium antagonist in treatment of hypertension. What protects the heart better?].
    MMW Fortschritte der Medizin, 2004, Jun-24, Volume: 146, Issue:26

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Cardiovascular Diseases; Clinical Trials as Topic; Dose-Response Relationship, Drug; Humans; Hypertension; Risk Factors; Tetrazoles; Valine; Valsartan

2004
[VALUE study underscores the significance of reaching aimed blood pressure values for minimizing cardiovascular risks].
    Praxis, 2004, Oct-13, Volume: 93, Issue:42

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diuretics; Double-Blind Method; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Prospective Studies; Randomized Controlled Trials as Topic; Risk Factors; Sodium Chloride Symporter Inhibitors; Tetrazoles; Time Factors; Valine; Valsartan

2004
[VALUE study underscores the importance of reaching goal blood pressure values for minimization of cardiovascular risks].
    Praxis, 2004, Oct-27, Volume: 93, Issue:44

    Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Cardiovascular Diseases; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Humans; Male; Prospective Studies; Randomized Controlled Trials as Topic; Reference Values; Risk Factors; Tetrazoles; Time Factors; Valine; Valsartan

2004
Angiotensin receptor blockers and myocardial infarction.
    BMJ (Clinical research ed.), 2004, Nov-27, Volume: 329, Issue:7477

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Myocardial Infarction; Tetrazoles; Truth Disclosure; Valine; Valsartan

2004
Valuable lessons from VALUE.
    Blood pressure, 2004, Volume: 13, Issue:4

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Humans; Hypertension; Tetrazoles; Valine; Valsartan

2004
The value of VALUE: the importance of lowering blood pressure quickly.
    International journal of clinical practice, 2004, Volume: 58, Issue:10

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Hypertension; Middle Aged; Risk Factors; Tetrazoles; Valine; Valsartan

2004
Is there more to life than blood pressure?
    Journal of clinical hypertension (Greenwich, Conn.), 2005, Volume: 7, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan

2005
In search of true value.
    Journal of clinical hypertension (Greenwich, Conn.), 2005, Volume: 7, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Humans; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan

2005
Angiotensin II type 2 receptor expression after vascular injury: differing effects of angiotensin-converting enzyme inhibition and angiotensin receptor blockade.
    Hypertension (Dallas, Tex. : 1979), 2006, Volume: 48, Issue:5

    Topics: Amlodipine; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Blood Pressure; Carotid Artery, Common; Cyclic GMP; Male; Rats; Rats, Inbred BN; Receptor, Angiotensin, Type 2; Tetrazoles; Tunica Intima; Tunica Media; Valine; Valsartan

2006
Lack of pharmacokinetic interactions of aliskiren, a novel direct renin inhibitor for the treatment of hypertension, with the antihypertensives amlodipine, valsartan, hydrochlorothiazide (HCTZ) and ramipril in healthy volunteers.
    International journal of clinical practice, 2006, Volume: 60, Issue:11

    Topics: Adolescent; Adult; Amides; Amlodipine; Antihypertensive Agents; Drug Interactions; Drug Therapy, Combination; Female; Fumarates; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Ramipril; Renin; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan

2006
Retinopathy and choroidopathy as the initial signs of hypertensive brainstem encephalopathy.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2006, Volume: 124, Issue:12

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Brain Stem; Choroid Diseases; Drug Therapy, Combination; Female; Fluorescein Angiography; Humans; Hypertensive Encephalopathy; Magnetic Resonance Imaging; Metoprolol; Middle Aged; Retinal Diseases; Tetrazoles; Valine; Valsartan

2006
Added VALUE of an ancillary study on ambulatory blood pressure monitoring.
    Journal of hypertension, 2007, Volume: 25, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Heart Rate; Humans; Hypertrophy, Left Ventricular; Randomized Controlled Trials as Topic; Reproducibility of Results; Research; Sample Size; Tetrazoles; Valine; Valsartan

2007
Risk of diabetes in a real-world setting among patients initiating antihypertensive therapy with valsartan or amlodipine.
    Journal of human hypertension, 2007, Volume: 21, Issue:5

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Databases, Factual; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Hypertension; Male; Middle Aged; Multivariate Analysis; Retrospective Studies; Risk Assessment; Risk Factors; Risk Reduction Behavior; Tetrazoles; Time Factors; Treatment Outcome; United States; Valine; Valsartan

2007
Angiotensin II receptor blockers downsize adipocytes in spontaneously type 2 diabetic rats with visceral fat obesity.
    American journal of hypertension, 2007, Volume: 20, Issue:4

    Topics: Adipocytes; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Blood Glucose; Calcium Channel Blockers; Cell Size; Diabetes Mellitus, Type 2; Disease Models, Animal; Insulin; Intra-Abdominal Fat; Male; Obesity; PPAR gamma; Random Allocation; Rats; Rats, Long-Evans; Telmisartan; Tetrazoles; Valine; Valsartan

2007
Novel mechanism and role of angiotensin II induced vascular endothelial injury in hypertensive diastolic heart failure.
    Arteriosclerosis, thrombosis, and vascular biology, 2007, Volume: 27, Issue:12

    Topics: Acetophenones; Amlodipine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Apoptosis; Biopterins; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Endothelium, Vascular; Heart Failure, Diastolic; Hydralazine; Hypertension; Male; MAP Kinase Kinase Kinase 5; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Rats; Rats, Inbred Dahl; Receptor, Angiotensin, Type 1; Signal Transduction; Sodium Chloride, Dietary; Superoxides; Tetrazoles; Time Factors; Valine; Valsartan; Vasodilation

2007
[Risk oriented therapy of hypertension. Lowering blood pressure and risk].
    MMW Fortschritte der Medizin, 2007, Nov-15, Volume: 149, Issue:46

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Diabetic Nephropathies; Humans; Hypertension; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan

2007
Two amlodipine/ARB combinations for hypertension.
    The Medical letter on drugs and therapeutics, 2007, Dec-17, Volume: 49, Issue:1276

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Humans; Hypertension; Imidazoles; Tetrazoles; Treatment Outcome; Valine; Valsartan

2007
Decreased expression of angiotensin II type 1 and type 2 receptors in the brain after long-term administration of antihypertensive drugs in stroke-prone spontaneously hypertensive rat.
    Journal of pharmacological sciences, 2008, Volume: 106, Issue:4

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Brain Stem; Calcium Channel Blockers; Cerebral Cortex; Disease Models, Animal; Down-Regulation; Enalapril; Hypertension; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Stroke; Tetrazoles; Time Factors; Valine; Valsartan

2008
Prolonged severe hypotension following combined amlodipine and valsartan ingestion.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:5

    Topics: Aged; Amlodipine; Antidotes; Antihypertensive Agents; Blood Glucose; Calcium Channel Blockers; Cardiac Catheterization; Drug Interactions; Drug Overdose; Female; Glucagon; Humans; Hypotension; Insulin; Naloxone; Severity of Illness Index; Suicide, Attempted; Tetrazoles; Time Factors; Valine; Valsartan

2008
Application in the STRATHE trial of a score system to compare the efficacy and the tolerability of different therapeutic strategies in the management of hypertension.
    Vascular health and risk management, 2008, Volume: 4, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Atenolol; Double-Blind Method; Drug Therapy, Combination; France; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Losartan; Perindopril; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan

2008
Adherence with multiple-combination antihypertensive pharmacotherapies in a US managed care database.
    Clinical therapeutics, 2008, Volume: 30, Issue:8

    Topics: Adolescent; Adult; Age Factors; Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Insurance Claim Review; Male; Managed Care Programs; Middle Aged; Patient Compliance; Tetrazoles; United States; Valine; Valsartan

2008
Cost-effectiveness analysis: controlled-release nifedipine and valsartan combination therapy in patients with essential hypertension: the adalat CR and valsartan cost-effectiveness combination (ADVANCE-Combi) study.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2008, Volume: 31, Issue:7

    Topics: Amlodipine; Cost-Benefit Analysis; Delayed-Action Preparations; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Japan; Nifedipine; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan

2008
Effectiveness of add-on therapy with amlodipine in hypertensive patients receiving valsartan.
    Blood pressure. Supplement, 2008, Volume: 2

    Topics: Adolescent; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cohort Studies; Databases, Factual; Drug Resistance; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Retrospective Studies; Tetrazoles; Treatment Outcome; Valine; Valsartan; Young Adult

2008
Development and validation of a highly sensitive and robust LC-ESI-MS/MS method for simultaneous quantitation of simvastatin acid, amlodipine and valsartan in human plasma: application to a clinical pharmacokinetic study.
    Biomedical chromatography : BMC, 2009, Volume: 23, Issue:6

    Topics: Acetonitriles; Amlodipine; Antihypertensive Agents; Chromatography, High Pressure Liquid; Humans; Male; Reproducibility of Results; Sensitivity and Specificity; Simvastatin; Spectrometry, Mass, Electrospray Ionization; Tandem Mass Spectrometry; Tetrazoles; Time Factors; Valine; Valsartan

2009
Triple fixed-dose combination therapy: back to the past.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Systole; Tetrazoles; Treatment Outcome; Valine; Valsartan

2009
Exforge HCT.
    The Medical letter on drugs and therapeutics, 2009, Jun-15, Volume: 51, Issue:1314

    Topics: Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Drug Combinations; Drug Costs; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan

2009
Re: Efficacy and safety of the single pill combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not controlled by amlodipine 10 mg plus olmesartan 20 mg in free combination.
    Current medical research and opinion, 2009, Volume: 25, Issue:9

    Topics: Amlodipine; Antihypertensive Agents; Clinical Trials as Topic; Dosage Forms; Dose-Response Relationship, Drug; Drug Combinations; Drug Resistance; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Tablets; Tetrazoles; Treatment Failure; Treatment Outcome; Valine; Valsartan

2009
Amlodipine/valsartan/hydrochlorothiazide: fixed-dose combination in hypertension.
    American journal of cardiovascular drugs : drugs, devices, and other interventions, 2009, Volume: 9, Issue:6

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Clinical Trials, Phase III as Topic; Drug Combinations; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan

2009
[Intermedin (IMD) gene expression in hypertrophic cardiac myocyte of renal vascular hypertension rats and the intervention of Valsartan, Amlodipine and Enalapril in the expression].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2009, Volume: 26, Issue:5

    Topics: Adrenomedullin; Amlodipine; Animals; Antihypertensive Agents; Cardiomegaly; Enalapril; Hypertension, Renovascular; Male; Myocardium; Neuropeptides; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tetrazoles; Valine; Valsartan

2009
Role of valsartan, amlodipine and hydrochlorothiazide fixed combination in blood pressure control: an update.
    Vascular health and risk management, 2010, Apr-15, Volume: 6

    Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Tetrazoles; Valine; Valsartan

2010
Comparison of amlodipine/valsartan fixed-dose combination therapy and conventional therapy.
    Managed care (Langhorne, Pa.), 2010, Volume: 19, Issue:7

    Topics: Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Female; Health Services; Humans; Hypertension; Male; Medical Audit; Middle Aged; Outcome Assessment, Health Care; Retrospective Studies; Tetrazoles; Valine; Valsartan

2010
Simultaneous spectrofluorimetric determination of amlodipine besylate and valsartan in their combined tablets.
    Drug testing and analysis, 2010, Volume: 2, Issue:10

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Drug Combinations; Limit of Detection; Spectrophotometry; Tablets; Tetrazoles; Valine; Valsartan

2010
The N-type and L-type calcium channel blocker cilnidipine suppresses renal injury in Dahl rats fed a high-salt diet.
    Heart and vessels, 2010, Volume: 25, Issue:6

    Topics: Albuminuria; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Disease Models, Animal; Drug Therapy, Combination; Glomerulonephritis; Hypertension; Kidney; Kidney Diseases; Male; Organ Size; Rats; Rats, Inbred Dahl; Rats, Sprague-Dawley; Sodium Chloride, Dietary; Tetrazoles; Time Factors; Valine; Valsartan

2010
Effects of an N-type calcium antagonist on angiotensin II-renin feedback.
    American journal of nephrology, 2011, Volume: 33, Issue:2

    Topics: Amlodipine; Angiotensin II; Animals; Calcium Channel Blockers; Calcium Channels, N-Type; Dihydropyridines; Dose-Response Relationship, Drug; Male; Models, Biological; Rats; Renin; Renin-Angiotensin System; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan

2011
Amlodipine + valsartan + hydrochlorothiazide. A 3-drug fixed-dose combination for hypertension: too many drawbacks.
    Prescrire international, 2011, Volume: 20, Issue:114

    Topics: Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Packaging; Humans; Hydrochlorothiazide; Hypertension; Medication Errors; Tetrazoles; Valine; Valsartan

2011
Comparison of real-world adherence, healthcare resource utilization and costs for newly initiated valsartan/amlodipine single-pill combination versus angiotensin receptor blocker/calcium channel blocker free-combination therapy.
    Journal of medical economics, 2011, Volume: 14, Issue:5

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Drug Combinations; Female; Health Care Costs; Health Services; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Retrospective Studies; Tetrazoles; United States; Valine; Valsartan

2011
Beneficial effects of combination of valsartan and amlodipine on salt-induced brain injury in hypertensive rats.
    The Journal of pharmacology and experimental therapeutics, 2011, Volume: 339, Issue:2

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain; Calcium Channel Blockers; Calcium Channels; Carotid Arteries; Drug Therapy, Combination; Endothelial Cells; Hypertension; Hypoxia-Ischemia, Brain; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Random Allocation; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Sodium Chloride, Dietary; Tetrazoles; Tyrosine; Valine; Valsartan

2011
Simple RP-HPLC method for determination of triple drug combination of valsartan, amlodipine and hydrochlorothiazide in human plasma.
    Acta pharmaceutica (Zagreb, Croatia), 2012, Volume: 62, Issue:1

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Diuretics; Drug Therapy, Combination; Guideline Adherence; Guidelines as Topic; Humans; Hydrochlorothiazide; Reproducibility of Results; Tetrazoles; Valine; Valsartan; Vasodilator Agents

2012
A comparison of the effects of fixed dose vs. single-agent combinations on 24-h blood pressure variability.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2012, Volume: 35, Issue:11

    Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Time Factors; Valine; Valsartan

2012
Additive effects of cilnidipine and angiotensin II receptor blocker in preventing the progression of diabetic nephropathy in diabetic spontaneously hypertensive rats.
    Clinical and experimental nephrology, 2013, Volume: 17, Issue:1

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dihydropyridines; Disease Progression; Drug Therapy, Combination; Glomerulonephritis; Glucagon; Glucose Transporter Type 1; Glycated Hemoglobin; Glycogen; Hypertension; Kidney; Male; Norepinephrine; Proteinuria; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Tetrazoles; Transforming Growth Factor beta1; Valine; Valsartan

2013
Improving drug adherence using fixed combinations caused beneficial treatment outcomes and decreased health-care costs in patients with hypertension.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2013, Volume: 35, Issue:5

    Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Health Care Costs; Humans; Hypertension; Male; Medication Adherence; Middle Aged; Prospective Studies; Retrospective Studies; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan

2013
Exfoliative esophagitis in a patient with metastatic renal cell carcinoma during sunitinib treatment.
    Medical oncology (Northwood, London, England), 2013, Volume: 30, Issue:1

    Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Aspirin; Carcinoma, Renal Cell; Cyclooxygenase 2 Inhibitors; Esophagitis; Humans; Hypertension; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Nephrectomy; Pyrroles; Sunitinib; Tetrazoles; Valine; Valsartan

2013
Concurrent estimation of amlodipine besylate, hydrochlorothiazide and valsartan by RP-HPLC, HPTLC and UV-spectrophotometry.
    Journal of chromatographic science, 2014, Volume: 52, Issue:1

    Topics: Amlodipine; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Combinations; Hydrochlorothiazide; Linear Models; Reproducibility of Results; Sensitivity and Specificity; Spectrophotometry, Ultraviolet; Tablets; Tetrazoles; Valine; Valsartan

2014
Pill burden in hypertensive patients treated with single-pill combination therapy--an observational study.
    Advances in therapy, 2013, Volume: 30, Issue:4

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Cost of Illness; Drug Combinations; Drug Therapy, Combination; Female; Germany; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan

2013
Amlodipine increases vitamin D levels more than valsartan in newly diagnosed hypertensive patients: pointing to an additional effect on bone metabolism or a novel marker of inflammation?
    Renal failure, 2013, Volume: 35, Issue:5

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Biomarkers; Bone Remodeling; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Valine; Valsartan; Vitamin D

2013
Comparative study between derivative spectrophotometry and multivariate calibration as analytical tools applied for the simultaneous quantitation of Amlodipine, Valsartan and Hydrochlorothiazide.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2013, Volume: 113

    Topics: Amlodipine; Calibration; Chemistry Techniques, Analytical; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Least-Squares Analysis; Multivariate Analysis; Reproducibility of Results; Spectrophotometry; Spectrophotometry, Ultraviolet; Tablets; Tetrazoles; Valine; Valsartan

2013
Different approaches in Partial Least Squares and Artificial Neural Network models applied for the analysis of a ternary mixture of Amlodipine, Valsartan and Hydrochlorothiazide.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2014, Mar-25, Volume: 122

    Topics: Amlodipine; Antihypertensive Agents; Dosage Forms; Hydrochlorothiazide; Least-Squares Analysis; Neural Networks, Computer; Principal Component Analysis; Spectrophotometry, Ultraviolet; Tetrazoles; Valine; Valsartan

2014
Efficacy and safety of valsartan/amlodipine single-pill combination in patients with essential hypertension (PEAK LOW).
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2014, Volume: 42, Issue:4

    Topics: Administration, Oral; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Hypertension; Male; Middle Aged; Tetrazoles; Treatment Outcome; Turkey; Valine; Valsartan

2014
Blood pressure control and satisfaction of hypertensive patients following a switch to combined drugs of an angiotensin receptor blocker and a calcium channel blocker in clinical practice of nephrology.
    Clinical and experimental nephrology, 2015, Volume: 19, Issue:3

    Topics: Aged; Amlodipine; Angiotensin Receptor Antagonists; Azetidinecarboxylic Acid; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Dihydropyridines; Drug Combinations; Drug Costs; Drug Substitution; Female; Humans; Hypertension; Imidazoles; Male; Medication Adherence; Middle Aged; Nephrology; Patient Satisfaction; Practice Patterns, Physicians'; Renal Insufficiency, Chronic; Retrospective Studies; Surveys and Questionnaires; Telmisartan; Tetrazoles; Valsartan

2015
Comparative effects of valsartan in combination with cilnidipine or amlodipine on cardiac remodeling and diastolic dysfunction in Dahl salt-sensitive rats.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2015, Volume: 38, Issue:1

    Topics: Amlodipine; Animals; Antihypertensive Agents; Dihydropyridines; Drug Evaluation, Preclinical; Drug Therapy, Combination; Heart; Hypertension; Hypertrophy, Left Ventricular; Male; Myocytes, Cardiac; Oxidative Stress; Rats, Inbred Dahl; Renin-Angiotensin System; Tetrazoles; Valine; Valsartan; Ventricular Remodeling

2015
Novel spectrophotometric methods for simultaneous determination of Amlodipine, Valsartan and Hydrochlorothiazide in their ternary mixture.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2015, Apr-05, Volume: 140

    Topics: Amlodipine; Antihypertensive Agents; Hydrochlorothiazide; Limit of Detection; Spectrophotometry; Tetrazoles; Valine; Valsartan

2015
Real-world effectiveness of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide in high-risk patients and other subgroups.
    Vascular health and risk management, 2015, Volume: 11

    Topics: Administration, Oral; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Asia; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Male; Middle Aged; Middle East; Prospective Studies; Tablets; Tetrazoles; Time Factors; Treatment Outcome; Valine; Valsartan

2015
A new, rapid, stability-indicating UPLC method for separation and determination of impurities in amlodipine besylate, valsartan and hydrochlorothiazide in their combined tablet dosage form.
    Journal of pharmaceutical and biomedical analysis, 2015, May-10, Volume: 109

    Topics: Amlodipine; Antihypertensive Agents; Chromatography, High Pressure Liquid; Drug Combinations; Drug Stability; Hydrochlorothiazide; Limit of Detection; Reference Standards; Reproducibility of Results; Solutions; Tablets; Valsartan

2015
[Sleep apnea: RR lowering drugs need to be administered in the evening].
    MMW Fortschritte der Medizin, 2015, Mar-26, Volume: 157 Suppl 1

    Topics: Amlodipine; Blood Pressure; Cross-Over Studies; Drug Chronotherapy; Drug Therapy, Combination; Humans; Hypertension; Sleep Apnea, Obstructive; Tetrazoles; Valine; Valsartan

2015
Protective effects of AT1-receptor blocker and CA antagonist combination on renal function in salt loaded spontaneously hypertensive rats.
    Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki), 2015, Volume: 36, Issue:1

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Body Weight; Calcium Channel Blockers; Creatinine; Hydrogen-Ion Concentration; Kidney; Kidney Function Tests; Male; Proteinuria; Rats; Rats, Inbred SHR; Sodium Chloride, Dietary; Urine; Valsartan

2015
New methods for amlodipine and valsartan native spectrofluorimetric determination, with factors optimization study.
    Talanta, 2015, Oct-01, Volume: 143

    Topics: Amlodipine; beta-Cyclodextrins; Hypromellose Derivatives; Magnetite Nanoparticles; Reproducibility of Results; Spectrometry, Fluorescence; Surface-Active Agents; Valsartan

2015
Simultaneous determination of valsartan, amlodipine besylate and hydrochlorothiazide using capillary zone electrophoresis (CZE).
    Die Pharmazie, 2015, Volume: 70, Issue:6

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Calibration; Diuretics; Drug Combinations; Electrophoresis, Capillary; Hydrochlorothiazide; Limit of Detection; Reference Standards; Reproducibility of Results; Tablets; Tetrazoles; Valine; Valsartan

2015
Improvement in Hemodynamics After Methylene Blue Administration in Drug-Induced Vasodilatory Shock: A Case Report.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2015, Volume: 11, Issue:4

    Topics: Amlodipine; Atenolol; Hemodynamics; Humans; Male; Methylene Blue; Middle Aged; Shock; Valsartan; Vasodilation

2015
Comparison of amlodipine/valsartan/hydrochlorothiazide single pill combination and free combination: adherence, persistence, healthcare utilization and costs.
    Current medical research and opinion, 2015, Volume: 31, Issue:12

    Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Cohort Studies; Drug Combinations; Female; Hospitalization; Humans; Hydrochlorothiazide; Hypertension; Male; Medication Adherence; Middle Aged; Patient Acceptance of Health Care; Retrospective Studies; Valsartan

2015
Clinical Effectiveness, Safety and Tolerability of Amlodipine/Valsartan in Hypertensive Patients: the Indonesian Subset of the EXCITE Study.
    Acta medica Indonesiana, 2015, Volume: 47, Issue:3

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Cough; Drug Combinations; Drug Substitution; Dyslipidemias; Edema; Female; Headache; Humans; Hypertension; Indonesia; Male; Medication Adherence; Middle Aged; Prospective Studies; Valsartan

2015
The effect of fixed-dose combination of valsartan and amlodipine on nighttime blood pressure in patients with non-dipper hypertension.
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2016, Volume: 44, Issue:5

    Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Cohort Studies; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Valsartan

2016
Quantitative model for the blood pressure-lowering interaction of valsartan and amlodipine.
    British journal of clinical pharmacology, 2016, Volume: 82, Issue:6

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Healthy Volunteers; Humans; Models, Biological; Predictive Value of Tests; Valsartan

2016
On the top of ARB N/L type Ca channel blocker leads to less elevation of aldosterone.
    Bioscience reports, 2016, Volume: 36, Issue:5

    Topics: Aged; Aldosterone; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Channels, N-Type; Dihydropyridines; Drug Combinations; Female; Humans; Hypertension; Male; Middle Aged; Renin-Angiotensin System; Valsartan

2016
Development and Validation of highly Sensitive Stability Indicating Spectrofluorimetric Method for Determination of Amlodipine in Pharmaceutical Preparations and Human Plasma.
    Journal of fluorescence, 2016, Volume: 26, Issue:6

    Topics: Amlodipine; Atorvastatin; Humans; Limit of Detection; Micelles; Pharmaceutical Preparations; Plasma; Spectrometry, Fluorescence; Tablets; Valsartan

2016
Novel Pure Component Contribution Algorithm (PCCA) and UHPLC Methods for Separation and Quantification of Amlodipine, Valsartan, and Hydrochlorothiazide in Ternary Mixture.
    Journal of AOAC International, 2017, May-01, Volume: 100, Issue:3

    Topics: Algorithms; Amlodipine; Antihypertensive Agents; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Tablets; Valsartan

2017
Development, validation and comparison of near infrared and Raman spectroscopic methods for fast characterization of tablets with amlodipine and valsartan.
    Talanta, 2017, May-15, Volume: 167

    Topics: Amlodipine; Calibration; Spectrophotometry, Infrared; Spectrum Analysis, Raman; Tablets; Tensile Strength; Time Factors; Valsartan

2017
Oxidative stress: link between hypertension and diabetes.
    The Korean journal of internal medicine, 2017, Volume: 32, Issue:3

    Topics: Amlodipine; Diabetes Mellitus, Type 2; Humans; Hypertension; Oxidative Stress; Valsartan

2017
Multiway analysis methods applied to the fluorescence excitation-emission dataset for the simultaneous quantification of valsartan and amlodipine in tablets.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2017, Sep-05, Volume: 184

    Topics: Algorithms; Amlodipine; Calibration; Databases, Chemical; Factor Analysis, Statistical; Least-Squares Analysis; Spectrometry, Fluorescence; Tablets; Valsartan

2017
mRNA levels of circadian clock components Bmal1 and Per2 alter independently from dosing time-dependent efficacy of combination treatment with valsartan and amlodipine in spontaneously hypertensive rats.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2017, Volume: 39, Issue:8

    Topics: Amlodipine; Animals; Antihypertensive Agents; Aorta; ARNTL Transcription Factors; Blood Pressure; Circadian Clocks; Drug Administration Schedule; Drug Therapy, Combination; Heart Ventricles; Hypertension; Kidney; Male; Period Circadian Proteins; Plasminogen Activator Inhibitor 1; Rats; Rats, Inbred SHR; RNA, Messenger; Valsartan

2017
Combination cardiovascular drugs.
    Nursing, 2017, Volume: 47, Issue:8

    Topics: Aminobutyrates; Amlodipine; Aspirin; Biphenyl Compounds; Cardiovascular Agents; Cardiovascular Diseases; Drug Combinations; Humans; Nebivolol; Omeprazole; Perindopril; Tetrazoles; Valsartan

2017
Blood pressure variability and risk of cardiovascular events and death in patients with hypertension and different baseline risks.
    European heart journal, 2018, 06-21, Volume: 39, Issue:24

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Mortality; Myocardial Infarction; Prognosis; Proportional Hazards Models; Stroke; Valsartan

2018
Comparison of real-world effectiveness between valsartan and non-RAS inhibitor monotherapy on the incidence of new diabetes in Chinese hypertensive patients: An electronic health recording system based study.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 2019, Volume: 41, Issue:3

    Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; China; Diabetic Angiopathies; Diuretics; Female; Humans; Hypertension; Male; Middle Aged; Valsartan

2019
Perindopril 3.5 mg/amlodipine 2.5 mg versus renin-angiotensin system inhibitor monotherapy as first-line treatment in hypertension: a combined analysis.
    Journal of hypertension, 2018, Volume: 36, Issue:9

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Female; Humans; Hypertension; Irbesartan; Male; Middle Aged; Perindopril; Randomized Controlled Trials as Topic; Renin-Angiotensin System; Valsartan

2018
Effects of amlodipine and valsartan on glibenclamide-treated streptozotocin-induced diabetic rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2018, Volume: 106

    Topics: Amlodipine; Animals; Antihypertensive Agents; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Progression; Drug Interactions; Glyburide; Hypoglycemic Agents; Male; Rats, Wistar; Risk Assessment; Streptozocin; Time Factors; Valsartan

2018
Identification and structure elucidation of a new degradation impurity in the multi-component tablets of amlodipine besylate.
    Journal of pharmaceutical and biomedical analysis, 2019, Jan-05, Volume: 162

    Topics: Amlodipine; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Drug Combinations; Drug Contamination; Drug Stability; Excipients; Formaldehyde; Hydrochlorothiazide; Magnetic Resonance Spectroscopy; Molecular Structure; Spectrometry, Mass, Electrospray Ionization; Time Factors; Valsartan

2019
[THE COMBINED THERAPY IN HYPERTENSIVE PATIENTS WITH DYSLIPIDEMIA].
    Georgian medical news, 2018, Issue:282

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Dyslipidemias; Fenofibrate; Humans; Hypertension; Hypolipidemic Agents; Middle Aged; Valsartan

2018
Measuring Central or Peripheral Blood Pressure Levels? That is the Question in the Modern Clinical Practice of Hypertension.
    High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension, 2018, Volume: 25, Issue:4

    Topics: Amlodipine; Blood Pressure; Blood Pressure Determination; Humans; Hypertension; Nebivolol; Valsartan

2018
Low-dose combination therapy to control sustained ambulatory hypertension-Basic principles and future directions.
    Journal of clinical hypertension (Greenwich, Conn.), 2019, Volume: 21, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Humans; Hypertension; Nifedipine; Valsartan; Vascular Stiffness

2019
A new strategy for taste masking on bitter drug by other combined drug in fixed-dose combination: bitterness of Amlodipine besylate could be masked efficiently by Valsartan.
    The Journal of pharmacy and pharmacology, 2019, Volume: 71, Issue:9

    Topics: Amlodipine; Benzazepines; Captopril; Dose-Response Relationship, Drug; Humans; Hydrochlorothiazide; Taste; Taste Perception; Telmisartan; Valsartan

2019
Effects of Different Antihypertensive Drug Combinations on Blood Pressure and Arterial Stiffness.
    Medical archives (Sarajevo, Bosnia and Herzegovina), 2019, Volume: 73, Issue:3

    Topics: Aged; Amlodipine; Antihypertensive Agents; Arteries; Blood Pressure; Diastole; Drug Combinations; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Lisinopril; Losartan; Male; Middle Aged; Prospective Studies; Pulse Wave Analysis; Systole; Valsartan; Vascular Resistance; Vascular Stiffness

2019
Single-pill combination of cilnidipine, an L-/N-type calcium channel blocker, and valsartan effectively reduces home pulse pressure in patients with uncontrolled hypertension and sympathetic hyperactivity: The HOPE-Combi survey.
    Journal of clinical hypertension (Greenwich, Conn.), 2020, Volume: 22, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Humans; Hypertension; Tetrazoles; Valsartan

2020
High performance liquid chromatographic assay of amlodipine, valsartan and hydrochlorothiazide simultaneously and its application to pharmaceuticals, urine and plasma analysis.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020, Oct-15, Volume: 1155

    Topics: Amlodipine; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Limit of Detection; Linear Models; Reproducibility of Results; Tablets; Valsartan

2020
Application of MEKC and UPLC with Fluorescence Detection for Simultaneous Determination of Amlodipine Besylate and Bisoprolol Fumarate.
    Journal of AOAC International, 2021, May-21, Volume: 104, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Bisoprolol; Chromatography, High Pressure Liquid; Chromatography, Micellar Electrokinetic Capillary; Valsartan

2021
Development and Validation of a UPLC-DAD Method for the Simultaneous Quantification of Eight Antihypertensive Drugs in the Pharmaceutical Matrix.
    Journal of AOAC International, 2021, Jun-12, Volume: 104, Issue:3

    Topics: Amlodipine; Antihypertensive Agents; Humans; Hydrochlorothiazide; Pharmaceutical Preparations; Tetrazoles; Valsartan

2021
Single-pill combination of cilnidipine, an l-/n-type calcium channel blocker, and valsartan reduces the day-by-day variability of morning home systolic blood pressure in patients with treated hypertension: A sub-analysis of the HOPE-combi survey.
    Journal of clinical hypertension (Greenwich, Conn.), 2021, Volume: 23, Issue:2

    Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Calcium Channels, L-Type; Dihydropyridines; Humans; Hypertension; Tetrazoles; Valsartan

2021
Cancer Risk of Angiotensin II Receptor Blocker Valsartan: A Population-based Study.
    Journal of cardiovascular pharmacology, 2022, 04-01, Volume: 79, Issue:4

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Humans; Hypertension; Neoplasms; Tetrazoles; Valine; Valsartan

2022
Eco-friendly spectrophotometric evaluation of triple-combination therapies in the treatment strategy of patients suffering from hypertension during coronavirus pandemic - Spectralprint recognition study.
    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 2022, Nov-05, Volume: 280

    Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Coronavirus; Humans; Hydrochlorothiazide; Hypertension; Leukemia, Myeloid, Acute; Pandemics; Spectrophotometry; Valsartan

2022
Benefits of Valsartan and Amlodipine in Lipolysis through PU.1 Inhibition in Fructose-Induced Adiposity.
    Nutrients, 2022, Sep-12, Volume: 14, Issue:18

    Topics: Activating Transcription Factor 3; Adiposity; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Fructose; Humans; Hypertension; Lipase; Lipolysis; Monoacylglycerol Lipases; Obesity; Stearoyl-CoA Desaturase; Tetrazoles; Triglycerides; Valsartan

2022
Efficacy and safety of single pill combination of amlodipine and valsartan in hypertensive Saudi patients.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Therapy, Combination; Humans; Hypertension; Leukemia, Myeloid, Acute; Prospective Studies; Saudi Arabia; Tetrazoles; Valsartan

2023
Improved Persistence to Medication, Decreased Cardiovascular Events and Reduced All-Cause Mortality in Hypertensive Patients With Use of Single-Pill Combinations: Results From the START-Study.
    Hypertension (Dallas, Tex. : 1979), 2023, Volume: 80, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Humans; Hypertension; Medication Adherence; Retrospective Studies; Tetrazoles; Valsartan

2023
Effect of Fixed-dose Combination Amlodipine/Valsartan in Comparison to Two Drug Combination Nebivolol/Valsartan on 24-Hour Ambulatory Blood Pressure.
    Current hypertension reviews, 2023, Volume: 19, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Combinations; Humans; Hypertension; Nebivolol; Tetrazoles; Treatment Outcome; Valine; Valsartan

2023
Effects of Valsartan and Amlodipine Tablets Combined with α-Lipoic Acid on T-AOC, IL-6 and β2-MG Levels in Patients with Diabetic Nephropathy.
    Alternative therapies in health and medicine, 2023, Volume: 29, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Antioxidants; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Hypertension; Interleukin-6; Tablets; Thioctic Acid; Valsartan

2023
Effects of 5-fluorouracil Co-administration on Blood Pressure in Patients Maintained on Antihypertensives: a Retrospective Case Series.
    Die Pharmazie, 2023, 05-01, Volume: 78, Issue:5

    Topics: Amlodipine; Antihypertensive Agents; Antineoplastic Agents; Blood Pressure; Cytochrome P-450 CYP3A; Drug Therapy, Combination; Fluorouracil; Humans; Hypertension; Nifedipine; Retrospective Studies; Tetrazoles; Valine; Valsartan

2023
NITROSOGENESIS OF SKIN CANCER: THE NITROSAMINE CONTAMINATION IN THE CALCIUM CHANNEL BLOCKERS (AMLODIPINE), BETA BLOCKERS (BISOPROLOL), SARTANS (VALSARTAN/LOSARTAN), ACE INHIBITORS (PERINDOPRIL/ENALAPRIL), TRICYCLIC ANTIDEPRESSANTS (MELITRACEN), SSRIS (PAR
    Georgian medical news, 2023, Issue:339

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antidepressive Agents, Tricyclic; Bisoprolol; Calcium Channel Blockers; Enalapril; Humans; Incidence; Losartan; Metformin; Paroxetine; Perindopril; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Skin Neoplasms; Valsartan; Venlafaxine Hydrochloride

2023
NITROSOGENESIS OF CUTANEOUS MELANOMA: SIMULTANEOUSLY DEVELOPMENT OF PRIMARY CUTANEOUS THICK MELANOMA OF THE BREAST, THIN MELANOMA/DYSPLASTIC MOLE OF THE BACK DURING PARALLEL INTAKE OF BISOPROLOL, AMLODIPINE AND VALSARTAN/ HCT: NITROSAMINE POLYCONTAMINATIO
    Georgian medical news, 2023, Issue:339

    Topics: Amlodipine; Bisoprolol; Humans; Melanoma; Melanoma, Cutaneous Malignant; Mutagens; Skin Neoplasms; Valsartan

2023
NITROSAMINE CONTAMINATION WITHIN CARDIAC MULTIMEDICATION - SARTANS (VALSARTAN), CALCIUM CHANNEL BLOCKERS (AMLODIPINE AND NIFEDIPINE), AND ANTIARRHYTHMICS (PROPAFENONE) AS A SIGNIFICANT FACTOR IN THE DEVELOPMENT AND PROGRESSION OF MULTIPLE KERATINOCYTIC CA
    Georgian medical news, 2023, Issue:342

    Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Anti-Arrhythmia Agents; Calcium Channel Blockers; Carcinogens; Humans; Keratoacanthoma; Neoplasms; Nifedipine; Nitrosamines; Propafenone; Shoulder; Surgical Flaps; Valsartan

2023