valproic acid and vitamin b 12

valproic acid has been researched along with vitamin b 12 in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's2 (8.70)18.2507
2000's14 (60.87)29.6817
2010's6 (26.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elmazar, MM; Nau, H; Thiel, R1
Hosokawa, K; Kugoh, T1
Fiehn, W; Kohl, B; Rieser, PA; Ringleb, P; Schwaninger, M; Walter-Sack, I; Winter, R1
Apeland, T; Kristensen, O; Mansoor, MA; Strandjord, RE1
Caksen, H; Geda, G; Içağasioğlu, D1
Karabiber, H; Otlu, B; Ozerol, E; Sonmezgoz, E; Yakinci, C; Yologlu, S1
Padmanabhan, R; Shafiullah, MM1
Gidal, BE; Hammer, A; Tamura, T; Vuong, A1
Kafantaris, V; Saito, E; Tsivkin, R1
Coker, I; Karaguzel, O; Ozdamar, O; Sener, U; Topbas, M; Zorlu, Y1
Benedict, S; Nagelkerke, N; Padmanabhan, R; Shafiullah, M1
Keown, P; McAllister-Williams, H; Young, A1
Attilakos, A; Garoufi, A; Katsarou, E; Mastroyianni, S; Papakonstantinou, E; Schulpis, K; Voudris, K1
Boisson, C; Candito, M; Gaucherand, P; Guéant, JL; Luton, D; Naimi, M; Rudigoz, JC; Van Obberghen, E1
Kurul, S; Unalp, A; Yiş, U1
Akin, R; Demirkaya, E; Gokçay, E; Gul, D; Kul, M; Unay, B; Vurucu, S1
Bek, S; Cakir, E; Gökçil, Z; Odabaşi, Z; Oz, O1
Aydogdu, SD; Colak, O; Dinleyici, EC; Ozdemir, O; Yakut, A; Yarar, C1
Bochyńska, A; Graban, A; Gugała-Iwaniuk, M; Lechowicz, W; Lipczyńska-Łojkowska, W; Lipska, B; Restel, M; Ryglewicz, D1
Keenan, N; Sadlier, LG; Wiltshire, E1
Chen, Y; Chen, Z; Fang, Z; Huang, M; Li, H; Ni, G; Qin, J; Zhou, J; Zhou, L; Zhou, Y1
Sharma, TK; Sitaraman, S; Vardey, SK1
D'Cruz, S; Kapur, V; Kaur, R1

Trials

1 trial(s) available for valproic acid and vitamin b 12

ArticleYear
The effect of vitamin B supplementation on homocysteine metabolism and clinical state of patients with chronic epilepsy treated with carbamazepine and valproic acid.
    Seizure, 2012, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Dietary Supplements; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Valproic Acid; Vitamin B 12; Vitamin B Complex; Young Adult

2012

Other Studies

22 other study(ies) available for valproic acid and vitamin b 12

ArticleYear
Effect of supplementation with folinic acid, vitamin B6, and vitamin B12 on valproic acid-induced teratogenesis in mice.
    Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:3

    Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Drug Interactions; Embryo, Mammalian; Female; Leucovorin; Mice; Mice, Inbred Strains; Pregnancy; Pyridoxine; Teratogens; Valproic Acid; Vitamin B 12

1992
Pharmacodynamic factors in the occurrence of psychiatric symptoms among patients with epilepsy.
    Folia psychiatrica et neurologica japonica, 1983, Volume: 37, Issue:3

    Topics: Anticonvulsants; Barbiturates; Carbamazepine; Epilepsy; Folic Acid; Humans; Kinetics; Mental Disorders; Phenobarbital; Phenytoin; Primidone; Valproic Acid; Vitamin B 12

1983
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment.
    Epilepsia, 1999, Volume: 40, Issue:3

    Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epilepsy; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Pyridoxine; Risk Factors; Sex Factors; Valproic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency

1999
Homocysteine concentrations and methionine loading in patients on antiepileptic drugs.
    Acta neurologica Scandinavica, 2000, Volume: 101, Issue:4

    Topics: Adult; Aged; Anticonvulsants; Carbamazepine; Case-Control Studies; Cytochrome P-450 Enzyme System; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methionine; Middle Aged; Phenobarbital; Phenytoin; Primidone; Treatment Outcome; Valproic Acid; Vitamin B 12

2000
Serum lipids, vitamin B12 and folic acid levels in children receiving long-term valproate therapy.
    Acta neurologica Belgica, 2002, Volume: 102, Issue:3

    Topics: Anticonvulsants; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Humans; Infant; Lipids; Male; Valproic Acid; Vitamin B 12

2002
Effects of valproate and carbamazepine on serum levels of homocysteine, vitamin B12, and folic acid.
    Brain & development, 2003, Volume: 25, Issue:2

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Reference Values; Valproic Acid; Vitamin B 12

2003
Amelioration of sodium valproate-induced neural tube defects in mouse fetuses by maternal folic acid supplementation during gestation.
    Congenital anomalies, 2003, Volume: 43, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Dietary Supplements; Disease Models, Animal; Enzyme Inhibitors; Female; Folic Acid; Maternal Exposure; Mice; Neural Tube Defects; Time Factors; Valproic Acid; Vitamin B 12

2003
Blood homocysteine, folate and vitamin B-12 concentrations in patients with epilepsy receiving lamotrigine or sodium valproate for initial monotherapy.
    Epilepsy research, 2005, Volume: 64, Issue:3

    Topics: Adult; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Lamotrigine; Male; Middle Aged; Triazines; Valproic Acid; Vitamin B 12

2005
Macrocytosis associated with divalproex treatment.
    Journal of child and adolescent psychopharmacology, 2005, Volume: 15, Issue:6

    Topics: Anemia, Macrocytic; Anticonvulsants; Bipolar Disorder; Child; Dose-Response Relationship, Drug; Erythrocyte Indices; Female; Folic Acid; Follow-Up Studies; Humans; Platelet Count; Thrombocytopenia; Valproic Acid; Vitamin B 12

2005
Effects of common anti-epileptic drug monotherapy on serum levels of homocysteine, vitamin B12, folic acid and vitamin B6.
    Seizure, 2006, Volume: 15, Issue:2

    Topics: Adolescent; Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Middle Aged; Phenytoin; Pyridoxal Phosphate; Reference Values; Valproic Acid; Vitamin B 12

2006
Effect of maternal exposure to homocystine on sodium valproate-induced neural tube defects in the mouse embryos.
    European journal of nutrition, 2006, Volume: 45, Issue:6

    Topics: Abnormalities, Drug-Induced; Animals; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Female; Fetal Growth Retardation; Folic Acid; Gestational Age; Homocysteine; Homocystine; Mice; Neural Tube Defects; Pregnancy; Random Allocation; Teratogens; Valproic Acid; Vitamin B 12

2006
A case of pancytopenia.
    Journal of psychopharmacology (Oxford, England), 2006, Volume: 20, Issue:5

    Topics: Adult; Anticonvulsants; Folic Acid; Humans; Male; Pancytopenia; Schizophrenia; Schizophrenic Psychology; Valproic Acid; Vitamin B 12

2006
Early effect of sodium valproate and carbamazepine monotherapy on homocysteine metabolism in children with epilepsy.
    Epilepsy research, 2006, Volume: 71, Issue:2-3

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Prospective Studies; Pyridoxal Phosphate; Valproic Acid; Vitamin B 12

2006
Plasma vitamin values and antiepileptic therapy: case reports of pregnancy outcomes affected by a neural tube defect.
    Birth defects research. Part A, Clinical and molecular teratology, 2007, Volume: 79, Issue:1

    Topics: Adult; Anticonvulsants; Epilepsy; Female; Folic Acid; Genetic Predisposition to Disease; Homocysteine; Humans; Neural Tube Defects; Pregnancy; Pregnancy Complications; Pregnancy Outcome; Valproic Acid; Vitamin B 12; Vitamin B 6

2007
Homocysteine levels in epileptic children receiving antiepileptic drugs.
    Journal of child neurology, 2007, Volume: 22, Issue:12

    Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Oxcarbazepine; Valproic Acid; Vitamin B 12

2007
Evaluation of the relationship between C677T variants of methylenetetrahydrofolate reductase gene and hyperhomocysteinemia in children receiving antiepileptic drug therapy.
    Progress in neuro-psychopharmacology & biological psychiatry, 2008, Apr-01, Volume: 32, Issue:3

    Topics: Adolescent; Analysis of Variance; Anticonvulsants; Carbamazepine; Child; Chromatography, High Pressure Liquid; Electrochemistry; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Hyperhomocysteinemia; Male; Methylenetetrahydrofolate Reductase (NADPH2); Polymorphism, Genetic; Valproic Acid; Vitamin B 12

2008
Is asymmetric dimethylarginine responsible for the vascular events in patients under antiepileptic drug treatment?
    Epilepsy research, 2009, Volume: 87, Issue:1

    Topics: Adult; Anticonvulsants; Arginine; Arterial Occlusive Diseases; Carbamazepine; Drug Monitoring; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Statistics, Nonparametric; Valproic Acid; Vitamin B 12

2009
Serum asymmetric dimethylarginine (ADMA), homocysteine, vitamin B(12), folate levels, and lipid profiles in epileptic children treated with valproic acid.
    European journal of pediatrics, 2011, Volume: 170, Issue:7

    Topics: Adolescent; Anticonvulsants; Arginine; Biomarkers; Case-Control Studies; Child; Child, Preschool; Cholesterol; Cross-Sectional Studies; Drug Administration Schedule; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Lipids; Male; Triglycerides; Valproic Acid; Vitamin B 12; Vitamin B Complex

2011
Vascular function and risk factors in children with epilepsy: associations with sodium valproate and carbamazepine.
    Epilepsy research, 2014, Volume: 108, Issue:6

    Topics: Adolescent; Anticonvulsants; Aorta; Blood Glucose; Brachial Artery; Carbamazepine; Carotid Arteries; Cholesterol; Cholesterol, HDL; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Phosphoric Monoester Hydrolases; Risk Factors; Ultrasonography; Valproic Acid; Vitamin B 12

2014
Effects of antiepileptic drug monotherapy on one-carbon metabolism and DNA methylation in patients with epilepsy.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Anticonvulsants; Case-Control Studies; Cross-Sectional Studies; DNA Methylation; Epilepsy; Female; Folic Acid; Heterocyclic Compounds; Homocysteine; Humans; Lamotrigine; Long Interspersed Nucleotide Elements; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Triazines; Valproic Acid; Vitamin B 12; Young Adult

2015
Evaluate the Effect of Valproate Monotherapy on the Serum Homocysteine, Folate and Vitamin B12 Levels in Epileptic Children.
    Clinical laboratory, 2015, Volume: 61, Issue:8

    Topics: Adolescent; Age Factors; Anticonvulsants; Case-Control Studies; Child; Child, Preschool; Drug Monitoring; Epilepsy; Female; Folic Acid; Homocysteine; Humans; Male; Risk Factors; Time Factors; Treatment Outcome; Valproic Acid; Vitamin B 12

2015
An uncommon presentation of hyperhomocysteinemia and vitamin B
    Journal of medical case reports, 2019, Feb-18, Volume: 13, Issue:1

    Topics: Adult; Anticoagulants; Anticonvulsants; Brain; Diuretics, Osmotic; Glycerol; Heparin; Humans; Hyperhomocysteinemia; Intracranial Thrombosis; Magnetic Resonance Imaging; Male; Mannitol; Seizures; Valproic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B Complex; Warfarin

2019