valproic acid has been researched along with verapamil in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (7.89) | 18.7374 |
| 1990's | 11 (28.95) | 18.2507 |
| 2000's | 15 (39.47) | 29.6817 |
| 2010's | 9 (23.68) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nezu, JI; Ohashi, R; Oku, A; Sai, Y; Shimane, M; Tamai, I; Tsuji, A; Yabuuchi, H | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Dansette, PM; Fontana, E; Poli, SM | 1 |
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Cuddon, P; Fleming, A; Floto, RA; Goldsmith, P; Jahreiss, L; O'Kane, CJ; Pask, D; Rubinsztein, DC; Saiki, S; Sarkar, S; Siddiqi, FH; Ttofi, EK; Williams, A | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Akaike, N; Kameda, H; Kataoka, M; Takahashi, K; Ueno, S | 1 |
| De Sarro, A; De Sarro, GB; Nistico', G; Trimarchi, GR | 1 |
| Friedman, DL; Kastner, T | 1 |
| Czuczwar, SJ; Kleinrok, Z; Małek, U | 1 |
| Cookson, JC | 1 |
| Charlier, B; Maitre, M; Mandel, P; Vayer, P | 1 |
| Kolts, BE; Langfitt, M | 1 |
| Klemfuss, H; Kripke, DF | 1 |
| Abrosimov, IIu; Karpova, MN; Kryzhanovskiĭ, GN; Lakinina, MV; Pankov, OIu | 1 |
| Guieu, R; Kopeyan, C; Rochat, H | 1 |
| Kaplan, B; Swain, RA | 1 |
| Brandes, JL; Glasscock, ME; Hanson, MB; Jackson, CG | 1 |
| Boerlin, HL; Gitlin, MJ; Hammen, CL; Zoellner, LA | 1 |
| Erfurth, A; Evers, S; Frese, A; Husstedt, IW; Lüttmann, RJ | 1 |
| Bjerve, KS; Hagen, K; Stovner, LJ; Waage, A | 1 |
| Dainese, F; Maggioni, F; Mainardi, F; Ruffatti, S; Zanchin, G | 1 |
| Liu, HY; Liu, X; Liu, XD; Liu, YC; Wang, GJ; Xie, L; Yang, HW; Zhang, DM | 1 |
| Kumar, G; Maytal, J; Topper, L | 1 |
| Grosberg, BM; Lipton, RB; Robbins, MS; Vollbracht, S | 1 |
| Jensen, RH; Tfelt-Hansen, PC | 1 |
4 review(s) available for valproic acid and verapamil
| Article | Year |
|---|---|
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug treatment of bipolar depression and mania.
Topics: Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Bromocriptine; Carbamazepine; Cholinesterase Inhibitors; Clonidine; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Humans; Lithium; Monoamine Oxidase Inhibitors; Phosphatidylcholines; Tryptophan; Valproic Acid; Verapamil | 1985 |
Diagnosis, prophylaxis, and treatment of headaches in the athlete.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Chronic Disease; Cluster Headache; Dihydroergotamine; Female; GABA Agents; Headache; Humans; Male; Migraine Disorders; Nortriptyline; Physical Exertion; Psychomotor Performance; Recurrence; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sports; Sumatriptan; Tension-Type Headache; Valproic Acid; Vasodilator Agents; Verapamil | 1997 |
2 trial(s) available for valproic acid and verapamil
| Article | Year |
|---|---|
Bipolar depression and antidepressant-induced mania: a naturalistic study.
Topics: Adult; Ambulatory Care; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Carbamazepine; Drug Administration Schedule; Drug Therapy, Combination; Female; Fluoxetine; Follow-Up Studies; Humans; Lithium; Male; Monoamine Oxidase Inhibitors; Selective Serotonin Reuptake Inhibitors; Valproic Acid; Verapamil | 1998 |
Weight variations in the prophylactic therapy of primary headaches: 6-month follow-up.
Topics: Adrenergic beta-Antagonists; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Atenolol; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine with Aura; Migraine without Aura; Pizotyline; Propranolol; Tension-Type Headache; Valproic Acid; Vasodilator Agents; Verapamil; Weight Gain | 2005 |
32 other study(ies) available for valproic acid and verapamil
| Article | Year |
|---|---|
Na(+)-dependent carnitine transport by organic cation transporter (OCTN2): its pharmacological and toxicological relevance.
Topics: Biological Transport, Active; Carnitine; Carrier Proteins; Cations; Cells, Cultured; Dose-Response Relationship, Drug; Embryo, Mammalian; Humans; Hydrogen-Ion Concentration; Kidney; Membrane Proteins; Organic Cation Transport Proteins; Sodium; Solute Carrier Family 22 Member 5; Stereoisomerism | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Novel targets for Huntington's disease in an mTOR-independent autophagy pathway.
Topics: Animals; Autophagy; Calcium Channels, L-Type; Clonidine; Cyclic AMP; Humans; Huntington Disease; Imidazoline Receptors; Minoxidil; Protein Kinases; Signal Transduction; TOR Serine-Threonine Kinases; Type C Phospholipases; Verapamil | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship | 2008 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites.
Topics: Glutathione; Pharmacology; Sulfur Radioisotopes | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Effects of Ca2+ antagonists and antiepileptics on tetrodotoxin-sensitive Ca(2+)-conducting channels in isolated rat hippocampal CA1 neurons.
Topics: Animals; Anticonvulsants; Calcium; Calcium Channel Blockers; Calcium Channels; Cells, Cultured; Diltiazem; Dizocilpine Maleate; Dose-Response Relationship, Drug; Flunarizine; Hippocampus; Kinetics; Neurons; Nicardipine; Phenobarbital; Phenytoin; Pyramidal Tracts; Rats; Rats, Wistar; Sodium; Tetrodotoxin; Valproic Acid; Verapamil | 1992 |
Effects of some calcium antagonists upon the activity of common antiepileptic compounds on sound-induced seizures in DBA/2 mice.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Anticonvulsants; Body Temperature; Calcium Channel Blockers; Diltiazem; Drug Synergism; Flunarizine; Mice; Mice, Inbred DBA; Nimodipine; Phenobarbital; Phenytoin; Seizures; Valproic Acid; Verapamil | 1992 |
Verapamil and valproic acid treatment of prolonged mania.
Topics: Adolescent; Arousal; Bipolar Disorder; Drug Therapy, Combination; Humans; Intellectual Disability; Male; Motor Activity; Neurocognitive Disorders; Valproic Acid; Verapamil | 1992 |
Influence of calcium channel inhibitors upon the anticonvulsant efficacy of common antiepileptics against pentylenetetrazol-induced convulsions in mice.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Diltiazem; Drug Therapy, Combination; Ethosuximide; Male; Mice; Nifedipine; Pentylenetetrazole; Phenobarbital; Reference Values; Seizures; Valproic Acid; Verapamil | 1990 |
Effect of anticonvulsant drugs on gamma-hydroxybutyrate release from hippocampal slices: inhibition by valproate and ethosuximide.
Topics: Animals; Ethosuximide; Hippocampus; Hydroxybutyrates; Pentobarbital; Potassium; Rats; Rats, Inbred Strains; Sodium Oxybate; Trimethadione; Valproic Acid; Verapamil; Veratridine | 1987 |
Drugs and the liver.
Topics: Acetaminophen; Adult; Aspirin; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Cholestasis; Cimetidine; Fatty Liver; Female; Hepatic Artery; Hepatic Veins; Humans; Ketoconazole; Liver; Liver Diseases; Liver Neoplasms; Methyldopa; Necrosis; Nitrofurantoin; Peliosis Hepatis; Portal Vein; Valproic Acid; Verapamil | 1984 |
Antimanic drugs stabilize hamster circadian rhythms.
Topics: Animals; Arousal; Carbamazepine; Circadian Rhythm; Cricetinae; Dose-Response Relationship, Drug; Drug Administration Schedule; Lithium Carbonate; Male; Mesocricetus; Motor Activity; Psychotropic Drugs; Valproic Acid; Verapamil | 1995 |
[Anticonvulsant activity of sodium valproate and various calcium antagonists during their combined use in mice].
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Dihydropyridines; Diltiazem; Drug Therapy, Combination; Epilepsy; Male; Mice; Nifedipine; Valproic Acid; Verapamil | 1993 |
Utilization of aspirin, quinine and verapamil in the prevention and treatment of scorpion venom intoxication.
Topics: Animals; Aspirin; Female; gamma-Aminobutyric Acid; Lethal Dose 50; Mice; Mice, Inbred C57BL; Poisoning; Quinine; Scorpion Venoms; Valproic Acid; Verapamil | 1993 |
Medical treatment of headache after suboccipital acoustic tumor removal.
Topics: Adult; Cerebellar Neoplasms; Cerebellopontine Angle; Craniotomy; Drug Therapy, Combination; Female; Headache; Humans; Male; Middle Aged; Neuroma, Acoustic; Postoperative Complications; Retrospective Studies; Valproic Acid; Verapamil | 1998 |
Corticosteroid-induced acute mania during a cluster headache episode.
Topics: Acute Disease; Adolescent; Age of Onset; Antimanic Agents; Bipolar Disorder; Cluster Headache; Glucocorticoids; Humans; Male; Methylprednisolone; Middle Aged; Valproic Acid; Vasodilator Agents; Verapamil | 2001 |
Hereditary haemochromatosis in two cousins with cluster headache.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain Stem; Calcium Channel Blockers; Cluster Headache; Drug Resistance; Female; Ferritins; Genotype; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; HLA Antigens; Humans; Iron; Male; Membrane Proteins; Middle Aged; Migraine with Aura; Mutation, Missense; Phlebotomy; Serotonin Receptor Agonists; Sumatriptan; Transferrin; Valproic Acid; Verapamil | 2002 |
Increased P-glycoprotein function and level after long-term exposure of four antiepileptic drugs to rat brain microvascular endothelial cells in vitro.
Topics: Animals; Anticonvulsants; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Carbamazepine; Cells, Cultured; Cerebral Arteries; Cyclosporine; Dose-Response Relationship, Drug; Drug Administration Schedule; Endothelial Cells; Immunosuppressive Agents; Indicators and Reagents; Microcirculation; Phenobarbital; Phenytoin; Rats; Rhodamine 123; Sodium Channel Blockers; Time; Up-Regulation; Valproic Acid; Verapamil | 2008 |
Familial hemiplegic migraine with prolonged aura and multimodality imaging: a case report.
Topics: Adrenal Cortex Hormones; Anticonvulsants; Child; Electroencephalography; Female; Humans; Magnetic Resonance Angiography; Magnetic Resonance Imaging; Migraine with Aura; Positron-Emission Tomography; Seizures; Tomography, Emission-Computed, Single-Photon; Valproic Acid; Vasodilator Agents; Verapamil | 2009 |
Cluster headache associated with a sixth nerve palsy: a case report.
Topics: Abducens Nerve Diseases; Anti-Inflammatory Agents; Cluster Headache; Dexamethasone; GABA Agents; Humans; Male; Valproic Acid; Vasodilator Agents; Verapamil; Young Adult | 2011 |
Management of cluster headache.
Topics: Analgesics; Cluster Headache; Deep Brain Stimulation; Disease Management; Ergotamine; Fructose; Humans; Hypothalamus; Lithium; Methysergide; Oxygen; Prevalence; Randomized Controlled Trials as Topic; Sumatriptan; Topiramate; Valproic Acid; Verapamil | 2012 |