valproic acid has been researched along with tiagabine in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (28.57) | 18.2507 |
| 2000's | 18 (51.43) | 29.6817 |
| 2010's | 6 (17.14) | 24.3611 |
| 2020's | 1 (2.86) | 2.80 |
| Authors | Studies |
|---|---|
| Bruno-Blanch, L; Gálvez, J; García-Domenech, R | 1 |
| Andricopulo, AD; Moda, TL; Montanari, CA | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Pierce, MW; Shu, VS | 1 |
| Boellner, SW; el-Shourbagy, T; Granneman, GR; Guenther, HJ; Gustavson, LE; Qian, JX; Sommerville, KW | 1 |
| Pellock, JM | 1 |
| Bazil, CW; Pedley, TA | 1 |
| Morimoto, K; Sato, H; Suwaki, H; Watanabe, T; Yamamoto, Y | 1 |
| Anderson, GD | 1 |
| Boellner, SW; Granneman, GR; Guenther, HJ; Gustavson, LE; Sommerville, KW; Witt, GF | 1 |
| Eckstein-Ludwig, U; Fei, J; Schwarz, W | 1 |
| Amann, B; Erfurth, A; Grunze, H; Marcuse, A; Normann, C; Walden, J | 1 |
| Brodie, MJ; Butler, E; Duncan, R; Fraser, CM; Howatson, A; Lindsay, K; Sills, GJ; Thompson, GG | 1 |
| Akman, CI; Schubert, R | 1 |
| Bingmann, D; Bonnet, U; Hufnagel, A; Leniger, T; Wiemann, M | 1 |
| Bachański, M; Jóźwiak, S; Karkowska, B; Kmieć, T; Kuczyński, D | 1 |
| Ferrier, IN | 1 |
| Hurkacz, M; Kozik, A; Orzechowska-Juzwenko, K; Unolt, J; Wiela-Hojeńska, A | 1 |
| Rekling, JC | 1 |
| Shelton, RC | 1 |
| Gau, CS; Lin, CJ; Liou, HH; Shyu, MK; Wu, SP | 1 |
| Stahl, SM | 1 |
| Jedrzejczak, J | 1 |
| Auvinen, A; Keränen, T; Kharazmi, E; Peltola, J; Peltola, M; Raitanen, J | 1 |
| Błaszczyk, B; Chrościńska-Krawczyk, M; Czuczwar, SJ; Jankiewicz, K | 1 |
| Krzyzanowski, M; Luszczki, JJ; Swiader, MJ | 1 |
| Bahk, WM; Wang, HR; Woo, YS | 1 |
| Deeb, S; Logan, BK; McKeown, DA; Scott, KS; Torrance, HJ; Wylie, FM | 1 |
| Andres-Mach, M; Chmielewski, J; Florek-Luszczki, M; Kondrat-Wrobel, MW; Luszczki, JJ; Patrzylas, P; Szpringer, M; Zagaja, M; Zaluska, K | 1 |
| Battino, D; Bromley, R; Kochen, S; Meador, KJ; Pennell, PB; Thomas, SV; Tomson, T | 1 |
11 review(s) available for valproic acid and tiagabine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Handling seizure data: special problems.
Topics: Anticonvulsants; Clinical Trials as Topic; Data Interpretation, Statistical; Drug Therapy, Combination; Electroencephalography; Epilepsy; Epilepsy, Complex Partial; Epilepsy, Tonic-Clonic; gamma-Aminobutyric Acid; Humans; Nipecotic Acids; Tiagabine; Valproic Acid | 1993 |
Overview of lamotrigine and the new antiepileptic drugs: the challenge.
Topics: Acetates; Amines; Anticonvulsants; Child; Cyclohexanecarboxylic Acids; Drug Interactions; Epilepsy; Exanthema; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Phenylcarbamates; Propylene Glycols; Tiagabine; Treatment Outcome; Triazines; Valproic Acid; Vigabatrin | 1997 |
Advances in the medical treatment of epilepsy.
Topics: Acetates; Amines; Anticonvulsants; Carbamazepine; Cyclohexanecarboxylic Acids; Diazepam; Drug Approval; Drug Design; Drug Interactions; Drug Resistance; Epilepsy; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Injections, Intravenous; Ketones; Lamotrigine; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Phenylcarbamates; Phenytoin; Prodrugs; Propylene Glycols; Tiagabine; Topiramate; Triazines; United States; Valproic Acid; Vigabatrin | 1998 |
A mechanistic approach to antiepileptic drug interactions.
Topics: Acetates; Amines; Anticonvulsants; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cyclohexanecarboxylic Acids; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Induction; Ethosuximide; Felbamate; Fructose; Gabapentin; gamma-Aminobutyric Acid; Glucuronosyltransferase; Humans; Lamotrigine; Mixed Function Oxygenases; Nipecotic Acids; Phenobarbital; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 1998 |
Developments in mood stabilisers.
Topics: Anticonvulsants; Antidepressive Agents; Antipsychotic Agents; Bipolar Disorder; Carbamazepine; Electroconvulsive Therapy; Electromagnetic Fields; Fructose; Humans; Lamotrigine; Lithium; Nipecotic Acids; Psychotherapy; Suicide Prevention; Thyroxine; Tiagabine; Topiramate; Triazines; Valproic Acid | 2001 |
Treating bipolar depression.
Topics: Acetates; Affect; Amines; Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Bipolar Disorder; Carbamazepine; Cyclohexanecarboxylic Acids; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Isoxazoles; Lamotrigine; Lithium Compounds; Nipecotic Acids; Olanzapine; Oxcarbazepine; Pirenzepine; Tiagabine; Topiramate; Treatment Outcome; Triazines; Valproic Acid; Zonisamide | 2003 |
Anticonvulsants as anxiolytics, part 1: tiagabine and other anticonvulsants with actions on GABA.
Topics: Anti-Anxiety Agents; Anticonvulsants; Anxiety Disorders; Carbamazepine; Fructose; GABA Agonists; gamma-Aminobutyric Acid; Humans; Lamotrigine; Nipecotic Acids; Synapses; Tiagabine; Topiramate; Triazines; Valproic Acid | 2004 |
[Caffeine and antiepileptic drugs: experimental and clinical data].
Topics: Animals; Anticonvulsants; Caffeine; Carbamazepine; Dose-Response Relationship, Drug; Drug Interactions; Electroshock; Humans; Lamotrigine; Mice; Nipecotic Acids; Phenobarbital; Phenytoin; Seizures; Tiagabine; Triazines; Valproic Acid | 2007 |
Anticonvulsants to treat post-traumatic stress disorder.
Topics: Anti-Anxiety Agents; Anticonvulsants; Fructose; Humans; Lamotrigine; Nipecotic Acids; Stress Disorders, Post-Traumatic; Tiagabine; Topiramate; Triazines; Valproic Acid | 2014 |
Breastfeeding while on treatment with antiseizure medications: a systematic review from the ILAE Women Task Force
Topics: Breast Feeding; Cannabidiol; Carbamazepine; Child; Clobazam; Clonazepam; Epilepsy; Ethosuximide; Everolimus; Felbamate; Female; Fenfluramine; Gabapentin; Humans; Infant; Lacosamide; Lamotrigine; Levetiracetam; Oxcarbazepine; Phenobarbital; Phenytoin; Prospective Studies; Tiagabine; Topiramate; Valproic Acid; Vigabatrin; Zonisamide | 2022 |
5 trial(s) available for valproic acid and tiagabine
| Article | Year |
|---|---|
A single-dose study to define tiagabine pharmacokinetics in pediatric patients with complex partial seizures.
Topics: Anticonvulsants; Body Constitution; Child; Child, Preschool; Drug Therapy, Combination; Epilepsy, Complex Partial; Female; Humans; Male; Nipecotic Acids; Sleep Stages; Tiagabine; Valproic Acid | 1997 |
Lack of a clinically significant pharmacokinetic drug interaction between tiagabine and valproate.
Topics: Adolescent; Adult; Anticonvulsants; Dizziness; Drug Interactions; Drug Monitoring; Drug Therapy, Combination; Female; GABA Agonists; Humans; Male; Nipecotic Acids; Rhinitis; Seizures; Sleep Stages; Tiagabine; Time Factors; Tremor; Valproic Acid | 1998 |
Tiagabine appears not to be efficacious in the treatment of acute mania.
Topics: Acute Disease; Adult; Anticonvulsants; Bipolar Disorder; Drug Therapy, Combination; Female; GABA Antagonists; Hospitalization; Humans; Lithium; Male; Middle Aged; Nipecotic Acids; Psychiatric Status Rating Scales; Risperidone; Tiagabine; Treatment Outcome; Valproic Acid | 1999 |
[Gabitril as an additive drug in therapy of intractable epileptic seizures in children].
Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Clonazepam; Drug Therapy, Combination; Epilepsies, Partial; Epilepsy, Generalized; Felbamate; Female; Follow-Up Studies; Humans; Lamotrigine; Male; Nipecotic Acids; Nitrazepam; Oxcarbazepine; Phenylcarbamates; Phenytoin; Propylene Glycols; Tiagabine; Triazines; Valproic Acid; Vigabatrin | 2000 |
Tiagabine as add-on therapy may be more effective with valproic acid--open label, multicentre study of patients with focal epilepsy.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Carbamazepine; Child; Data Interpretation, Statistical; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance; Drug Therapy, Combination; Epilepsies, Partial; Female; Humans; Male; Middle Aged; Nipecotic Acids; Poland; Seizures; Sex Factors; Tiagabine; Treatment Outcome; Valproic Acid | 2005 |
19 other study(ies) available for valproic acid and tiagabine
| Article | Year |
|---|---|
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship | 2003 |
Hologram QSAR model for the prediction of human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship | 2007 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Antiepileptic effects of tiagabine, a selective GABA uptake inhibitor, in the rat kindling model of temporal lobe epilepsy.
Topics: Amygdala; Animals; Anticonvulsants; Behavior, Animal; Carbamazepine; Dose-Response Relationship, Drug; Electric Stimulation; Electroencephalography; Epilepsy, Temporal Lobe; gamma-Aminobutyric Acid; Kindling, Neurologic; Male; Neurotransmitter Uptake Inhibitors; Nipecotic Acids; Picrotoxin; Rats; Rats, Sprague-Dawley; Tiagabine; Valproic Acid | 1997 |
Inhibition of uptake, steady-state currents, and transient charge movements generated by the neuronal GABA transporter by various anticonvulsant drugs.
Topics: Acetates; Amines; Animals; Anticonvulsants; Binding Sites; Biological Transport; Carrier Proteins; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Electric Conductivity; Female; GABA Plasma Membrane Transport Proteins; Gabapentin; gamma-Aminobutyric Acid; Kinetics; Membrane Potentials; Membrane Proteins; Membrane Transport Proteins; Mice; Nipecotic Acids; Oocytes; Organic Anion Transporters; Patch-Clamp Techniques; Tiagabine; Valproic Acid; Vigabatrin; Xenopus laevis | 1999 |
Effects of valproate, vigabatrin and tiagabine on GABA uptake into human astrocytes cultured from foetal and adult brain tissue.
Topics: Adult; Anticonvulsants; Astrocytes; Carrier Proteins; Cells, Cultured; Female; Fetus; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Infant, Newborn; Membrane Proteins; Membrane Transport Proteins; Neural Inhibition; Nipecotic Acids; Organic Anion Transporters; Pregnancy; Pregnancy Trimester, Second; Temporal Lobe; Tiagabine; Valproic Acid; Vigabatrin | 1999 |
The role of tiagabine in the treatment of intractable epilepsy of childhood with multifocal independent spikes: a case report.
Topics: Anticonvulsants; Brain; Child; Drug Therapy, Combination; Electroencephalography; Epilepsy; Humans; Male; Nipecotic Acids; Tiagabine; Valproic Acid | 2000 |
Different effects of GABAergic anticonvulsants on 4-aminopyridine-induced spontaneous GABAergic hyperpolarizations of hippocampal pyramidal cells--implication for their potency in migraine therapy.
Topics: 4-Aminopyridine; Acetates; Amines; Analgesics; Animals; Anticonvulsants; Convulsants; Cyclohexanecarboxylic Acids; GABA Agonists; Gabapentin; gamma-Aminobutyric Acid; Guinea Pigs; Hippocampus; Humans; Membrane Potentials; Migraine Disorders; Nipecotic Acids; Pyramidal Cells; Tiagabine; Time Factors; Valproic Acid; Vigabatrin | 2000 |
[Monitoring of renal function in epileptic children and teenagers treated with valproic acid or carbamazepine in concomitant therapy with tiagabine].
Topics: Acetylglucosaminidase; Adolescent; Adult; Anticonvulsants; beta 2-Microglobulin; Carbamazepine; Case-Control Studies; Child; Controlled Clinical Trials as Topic; Dose-Response Relationship, Drug; Drug Therapy, Combination; Epilepsy; Female; Humans; Kidney; Kidney Function Tests; Kidney Glomerulus; Kidney Tubules; Male; Nipecotic Acids; Renal Insufficiency; Statistics, Nonparametric; Tiagabine; Time Factors; Valproic Acid | 2001 |
Neuroprotective effects of anticonvulsants in rat hippocampal slice cultures exposed to oxygen/glucose deprivation.
Topics: Acetates; Amines; Animals; Anticonvulsants; Carbamates; Carbamazepine; Cell Death; Cells, Cultured; Chlordiazepoxide; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Ethosuximide; Felbamate; Gabapentin; gamma-Aminobutyric Acid; Glucose; Hippocampus; Hypoxia; Ischemia; Lamotrigine; Levetiracetam; Midazolam; Neurons; Neuroprotective Agents; Nipecotic Acids; Oxcarbazepine; Phenobarbital; Phenylcarbamates; Phenylenediamines; Phenytoin; Piracetam; Propylene Glycols; Rats; Rats, Wistar; Tiagabine; Triazines; Valproic Acid | 2003 |
Interaction between anticonvulsants and human placental carnitine transporter.
Topics: Acetates; Amines; Aminoisobutyric Acids; Anticonvulsants; Carnitine; Carrier Proteins; Culture Techniques; Cyclohexanecarboxylic Acids; Dose-Response Relationship, Drug; Drug Administration Schedule; Epilepsy; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Models, Biological; Nipecotic Acids; Organic Cation Transport Proteins; Phenytoin; Placenta; Pregnancy; Pregnancy Complications; Pregnancy Proteins; Solute Carrier Family 22 Member 5; Tiagabine; Topiramate; Triazines; Valproic Acid; Vigabatrin | 2004 |
Seizure-freedom with combination therapy in localization-related epilepsy.
Topics: Adult; Anticonvulsants; Brain; Carbamazepine; Drug Therapy, Combination; Female; Frontal Lobe; Fructose; Humans; Lamotrigine; Levetiracetam; Male; Nipecotic Acids; Occipital Lobe; Oxcarbazepine; Parietal Lobe; Piracetam; Seizures; Temporal Lobe; Tiagabine; Topiramate; Treatment Outcome; Triazines; Valproic Acid | 2008 |
Interaction of tiagabine with valproate in the mouse pentylenetetrazole-induced seizure model: an isobolographic analysis for non-parallel dose-response relationship curves.
Topics: Animals; Anticonvulsants; Brain Chemistry; Convulsants; Dose-Response Relationship, Drug; Drug Interactions; Drug Therapy, Combination; Epilepsy; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Mice; Nipecotic Acids; Pentylenetetrazole; Random Allocation; Seizures; Tiagabine; Valproic Acid | 2009 |
Simultaneous analysis of 22 antiepileptic drugs in postmortem blood, serum and plasma using LC-MS-MS with a focus on their role in forensic cases.
Topics: Amines; Anticonvulsants; Carbamazepine; Chromatography, Liquid; Cyclohexanecarboxylic Acids; Drug Monitoring; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Lamotrigine; Levetiracetam; Limit of Detection; Nipecotic Acids; Oxcarbazepine; Phenytoin; Piracetam; Pregabalin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Tiagabine; Topiramate; Triazines; Valproic Acid | 2014 |
Effects of arachidonyl-2'-chloroethylamide (ACEA) on the protective action of various antiepileptic drugs in the 6-Hz corneal stimulation model in mice.
Topics: Acetamides; Animals; Anticonvulsants; Arachidonic Acids; Avoidance Learning; Benzodiazepines; Clobazam; Cornea; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Electroshock; Epilepsy, Complex Partial; Lacosamide; Levetiracetam; Male; Mice; Muscle Strength; Nipecotic Acids; Phenobarbital; Phenylmethylsulfonyl Fluoride; Piracetam; Psychomotor Performance; Receptor, Cannabinoid, CB1; Tiagabine; Valproic Acid | 2017 |