valproic acid has been researched along with thalidomide in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.23) | 18.7374 |
| 1990's | 1 (3.23) | 18.2507 |
| 2000's | 13 (41.94) | 29.6817 |
| 2010's | 13 (41.94) | 24.3611 |
| 2020's | 3 (9.68) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Holtzman, NA; Khoury, MJ | 1 |
| Johnson, EM | 1 |
| Eudy, JD; Finnell, RH; Rosenquist, TH; Waes, JG | 1 |
| Kato, M; Miyazaki, K; Narita, M; Narita, N; Okado, N; Tazoe, M | 1 |
| Holmes, LB | 1 |
| Rout, UK | 1 |
| Abe, M; Amou, H; Harada, T; Hashimoto, T; Hiasa, M; Kitazoe, KI; Matsumoto, T; Nakano, A; Oda, A; Ozaki, S; Takeuchi, K | 1 |
| Gattermann, N; Germing, U; Giagounidis, A; Haas, R; Kobbe, G; Kündgen, A; Nachtkamp, K; Strupp, C | 1 |
| Santini, V | 1 |
| Blum, S; Gattermann, N; Germing, U; Haas, R; Habersang, K; Kuendgen, A; Möller, I | 1 |
| Clausen, P; Rout, UK | 1 |
| Al-Kadhimi, Z; Alshekhlee, A; Djmil, M; Labro, H; Oghlakian, R | 1 |
| Scott, BL | 1 |
| Imura, Y; Kamada, N; Narita, M; Narita, N; Oyabu, A; Tano, K; Uchida, A; Yokoyama, T | 1 |
| Arango, BA; Cohen, EE; Perez, CA; Raez, LE; Santos, ES | 1 |
| Kmietowicz, Z | 1 |
| Ward, CS | 1 |
| Aikawa, N; Kunisato, A; Kusaka, H; Nagao, K; Ohgami, K; Takaba, K | 1 |
| Gao, X; Sprando, RL; Yourick, JJ | 1 |
| Mukherjee, S; Ornstein, MC; Sekeres, MA | 1 |
| Abdelrahim, M; Bilen, MA; Erguvan-Dogan, B; Falchook, GS; Fu, S; Hong, DS; Kurzrock, R; Naing, A; Ng, CS; Tsimberidou, AM; Wheler, JJ | 1 |
| Lazarewicz, JW; Lenart, J; Zieminska, E | 1 |
| Balleari, E; Bernal, T; Beyne-Rauzy, O; Bordessoule, D; Calabuig, M; Cametti, G; Campelo, MD; Cheze, S; Cony-Makhoul, P; Dreyfus, F; Fenaux, P; Fensterl, J; Ferrero, D; Gaidano, G; Germing, U; Gioia, D; Götze, K; Guerci-Bresler, A; Hamel, JF; Kaivers, J; Kelaidi, C; Komrokji, R; Kotsianidis, I; Müller-Thomas, C; Pane, F; Park, S; Ramos, F; Roboz, GJ; Rose, C; Sanna, A; Santini, V; Sanz, GF; Sapena, R; Sekeres, MA; Stamatoullas, A; Steensma, DP; Thépot, S; Toma, A; Vey, N; Wattel, E | 1 |
| Bratek, E; Lazarewicz, JW; Lenart, J; Zieminska, E | 1 |
| Emnéus, JK; Holst, B; Lauschke, K; Meiser, I; Neubauer, JC; Rasmussen, MA; Rosenmai, AK; Schmidt, K; Taxvig, C; Vinggaard, AM | 1 |
5 review(s) available for valproic acid and thalidomide
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Molecular basis of environmentally induced birth defects.
Topics: Abnormalities, Drug-Induced; Animals; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Genetic Predisposition to Disease; Humans; Pregnancy; Retinoids; Teratogens; Thalidomide; Valproic Acid | 2002 |
Teratogen-induced limb defects.
Topics: Chorionic Villi Sampling; Female; Humans; Limb Deformities, Congenital; Male; Misoprostol; Phenytoin; Pregnancy; Pregnancy in Diabetics; Substance-Related Disorders; Teratogens; Thalidomide; Valproic Acid; Warfarin | 2002 |
Novel molecular targeted therapies for refractory thyroid cancer.
Topics: Angiogenesis Inhibitors; Anilides; Antineoplastic Agents; Axitinib; Benzamides; Benzenesulfonates; Benzoquinones; Bibenzyls; Boronic Acids; Bortezomib; Depsipeptides; ErbB Receptors; Gefitinib; Histone Deacetylase Inhibitors; HSP90 Heat-Shock Proteins; Humans; Hydroxamic Acids; Imatinib Mesylate; Imidazoles; Indazoles; Indoles; Lactams, Macrocyclic; Lenalidomide; Niacinamide; Oligonucleotides; Phenylurea Compounds; Piperazines; Piperidines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-kit; Pyrazines; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Quinolines; Receptor Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sulfonamides; Sunitinib; Thalidomide; Thyroid Neoplasms; Valproic Acid; Vorinostat | 2012 |
More is better: combination therapies for myelodysplastic syndromes.
Topics: Antineoplastic Agents; Azacitidine; Benzamides; Clinical Trials as Topic; Decitabine; Disease Progression; Drug Therapy, Combination; Gene Expression; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Hydroxamic Acids; Lenalidomide; Leukemia, Myeloid, Acute; Myelodysplastic Syndromes; Pyrimidines; Thalidomide; Valproic Acid; Vorinostat | 2015 |
1 trial(s) available for valproic acid and thalidomide
| Article | Year |
|---|---|
Phase I trial of valproic acid and lenalidomide in patients with advanced cancer.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Lenalidomide; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Thalidomide; Treatment Outcome; Valproic Acid | 2015 |
25 other study(ies) available for valproic acid and thalidomide
| Article | Year |
|---|---|
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
On the ability of birth defects monitoring to detect new teratogens.
Topics: Abnormalities, Drug-Induced; Epidemiologic Methods; Humans; Infant, Newborn; Isotretinoin; Risk; Teratogens; Thalidomide; Tretinoin; Valproic Acid | 1987 |
A risk assessment of topical tretinoin as a potential human developmental toxin based on animal and comparative human data.
Topics: Abnormalities, Drug-Induced; Administration, Topical; Animals; Female; Humans; Isotretinoin; Keratolytic Agents; Methotrexate; Pregnancy; Risk Assessment; Teratogens; Thalidomide; Tretinoin; Valproic Acid | 1997 |
Increased monoamine concentration in the brain and blood of fetal thalidomide- and valproic acid-exposed rat: putative animal models for autism.
Topics: Animals; Autistic Disorder; Biogenic Monoamines; Brain; Female; Pregnancy; Rats; Rats, Sprague-Dawley; Teratogens; Thalidomide; Valproic Acid | 2002 |
Valproate, thalidomide and ethyl alcohol alter the migration of HTR-8/SVneo cells.
Topics: Cell Line; Cell Movement; Cell Proliferation; Cells, Cultured; Ethanol; Humans; Integrins; Thalidomide; Trophoblasts; Valproic Acid | 2006 |
Valproic acid exerts anti-tumor as well as anti-angiogenic effects on myeloma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Cell Proliferation; Cell Survival; Coculture Techniques; Drug Synergism; Histone Deacetylase Inhibitors; Humans; Multiple Myeloma; Osteoclasts; Thalidomide; Tumor Cells, Cultured; Valproic Acid | 2009 |
Impact on survival of different treatments for myelodysplastic syndromes (MDS).
Topics: Adult; Aged; Antilymphocyte Serum; Cytarabine; Disease-Free Survival; Enzyme Inhibitors; Female; Germany; Humans; Immunosuppressive Agents; Male; Middle Aged; Myelodysplastic Syndromes; Registries; Retrospective Studies; Risk Factors; Stem Cell Transplantation; Survival Rate; Thalidomide; Transplantation, Homologous; Valproic Acid | 2009 |
Is survival enough for myelodysplastic syndromes?
Topics: Adult; Aged; Antilymphocyte Serum; Cytarabine; Disease-Free Survival; Enzyme Inhibitors; Female; Germany; Humans; Immunosuppressive Agents; Male; Middle Aged; Myelodysplastic Syndromes; Registries; Retrospective Studies; Risk Factors; Stem Cell Transplantation; Survival Rate; Thalidomide; Transplantation, Homologous; Valproic Acid | 2009 |
Repeated responses of an elderly patient with high-risk myelodysplastic syndrome to sequential therapy with tipifarnib, 5-azacitidine, and decitabine.
Topics: Aged; Anemia, Refractory, with Excess of Blasts; Azacitidine; Benzene; Decitabine; DNA (Cytosine-5-)-Methyltransferases; Drug Therapy, Combination; Farnesyltranstransferase; Histone Deacetylase Inhibitors; Humans; Male; Occupational Exposure; Platelet Count; Quinolones; Thalidomide; Valproic Acid | 2009 |
Common increase of GATA-3 level in PC-12 cells by three teratogens causing autism spectrum disorders.
Topics: Animals; Autistic Disorder; Ethanol; GATA3 Transcription Factor; Gene Expression Profiling; PC12 Cells; Protein Binding; Rats; Teratogens; Thalidomide; Transcription Factors; Valproic Acid | 2009 |
Brain amyloidoma with cerebral hemorrhage.
Topics: Amyloidosis; Anticonvulsants; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cerebral Hemorrhage; Dexamethasone; Female; Glucocorticoids; Humans; Immunosuppressive Agents; Magnetic Resonance Imaging; Melphalan; Middle Aged; Thalidomide; Valproic Acid | 2009 |
Clinical roundtable monograph. Combination therapies for MDS.
Topics: Azacitidine; Carrier Proteins; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Colony-Stimulating Factors; Enzyme Inhibitors; Etanercept; Humans; Hydroxamic Acids; Immunoglobulin G; Lenalidomide; Myelodysplastic Syndromes; Platelet Transfusion; Receptors, Fc; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Thalidomide; Thrombopoietin; Valproic Acid; Vorinostat | 2009 |
Nonexploratory movement and behavioral alterations in a thalidomide or valproic acid-induced autism model rat.
Topics: Age Factors; Animals; Autistic Disorder; Disease Models, Animal; Exploratory Behavior; Female; Interpersonal Relations; Male; Maze Learning; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Thalidomide; Valproic Acid | 2010 |
More drug studies need to include pregnant women, says bulletin.
Topics: Anticonvulsants; Clinical Trials as Topic; Drug Industry; Female; Humans; Hypnotics and Sedatives; Mortality; Obesity; Pregnancy; Pregnancy Complications; Pregnant Women; Research Design; Teratogens; Thalidomide; United Kingdom; Valproic Acid | 2013 |
Autism's cancer connection: the anti-proliferation hypothesis and why it may matter.
Topics: Antineoplastic Agents; Autistic Disorder; Epigenetic Repression; Gene Expression Regulation, Neoplastic; Humans; Models, Biological; Neoplasms; Terbutaline; Thalidomide; Valproic Acid | 2014 |
Detection of thalidomide embryotoxicity by in vitro embryotoxicity testing based on human iPS cells.
Topics: Ascorbic Acid; Cell Differentiation; Cells, Cultured; Embryonic Stem Cells; Fibroblasts; Humans; Induced Pluripotent Stem Cells; Myocytes, Cardiac; Skin; Teratogens; Thalidomide; Toxicity Tests; Valproic Acid | 2014 |
Transcriptomic characterization of C57BL/6 mouse embryonic stem cell differentiation and its modulation by developmental toxicants.
Topics: Animals; Cell Differentiation; DNA, Complementary; Embryoid Bodies; Embryonic Stem Cells; Gastrulation; Gene Expression Regulation, Developmental; Gene Ontology; Mice; Mice, Inbred C57BL; Oligonucleotide Array Sequence Analysis; Phthalic Acids; RNA, Messenger; Thalidomide; Toxicity Tests; Transcriptome; Valproic Acid | 2014 |
Select putative neurodevelopmental toxins modify SNAP-25 expression in primary cultures of rat cerebellar granule cells.
Topics: Animals; Cells, Cultured; Cerebellum; Exocytosis; Gene Expression Regulation; Metal Nanoparticles; Neurodevelopmental Disorders; Neurons; Polybrominated Biphenyls; Rats; Rats, Wistar; RNA, Messenger; Silver; Synaptosomal-Associated Protein 25; Thalidomide; Thimerosal; Toxicity Tests; Valproic Acid | 2016 |
Outcome of Lower-Risk Patients With Myelodysplastic Syndromes Without 5q Deletion After Failure of Erythropoiesis-Stimulating Agents.
Topics: Aged; Aged, 80 and over; Anemia; Antilymphocyte Serum; Antineoplastic Agents; Arsenic; Azacitidine; Chromosome Deletion; Chromosomes, Human, Pair 5; Cyclosporine; Cytarabine; Decitabine; Disease Progression; Enzyme Inhibitors; Erythrocyte Transfusion; Female; Hematinics; Humans; Hydroxyurea; Immunologic Factors; Lenalidomide; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Recurrence; Retreatment; Retrospective Studies; Risk Factors; Survival Rate; Thalidomide; Treatment Failure; Tretinoin; Valproic Acid | 2017 |
Changes in the Expression of SNAP-25 Protein in the Brain of Juvenile Rats in Two Models of Autism.
Topics: Animals; Autistic Disorder; Brain; Female; Male; Rats; Synaptosomal-Associated Protein 25; Thalidomide; Valproic Acid | 2020 |
A novel human pluripotent stem cell-based assay to predict developmental toxicity.
Topics: Biological Assay; Cell Line; Developmental Biology; Embryoid Bodies; Epoxy Compounds; Female; Humans; Male; Myocytes, Cardiac; Oxazines; Pluripotent Stem Cells; Teratogenesis; Teratogens; Thalidomide; Toxicity Tests; Triazoles; Valproic Acid; Xanthenes | 2020 |