valproic acid has been researched along with sorbinil in 8 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Demopoulos, VJ; Koukoulitsa, C; Nicolaou, I; Pegklidou, K | 1 |
| Alexiou, P; Demopoulos, VJ | 1 |
| Demopoulos, VJ; Kotsampasakou, E | 1 |
| Chatzopoulou, M; Demopoulos, VJ; Kristl, A; Patsilinakos, A; Prnova, MS; Ragno, R; Stefek, M; Tsantili-Kakoulidou, A; Vallianatou, T; Zakelj, S | 1 |
| Ali, S; Hameed, S; Iqbal, J; Iqbal, Z; Shahid, M; Tehseen, Y | 1 |
| Balestri, F; Ballekova, J; Cappiello, M; Chatzopoulou, M; Moschini, R; Nicolaou, I; Papastavrou, N; Patsilinakos, A; Ragno, R; Stefek, M | 1 |
| Poulsom, R | 1 |
| De Jongh, KS; Edwards, MR; Schofield, PJ; Smith, MM | 1 |
8 other study(ies) available for valproic acid and sorbinil
| Article | Year |
|---|---|
Design and synthesis of novel series of pyrrole based chemotypes and their evaluation as selective aldose reductase inhibitors. A case of bioisosterism between a carboxylic acid moiety and that of a tetrazole.
Topics: Aldehyde Reductase; Animals; Carboxylic Acids; Drug Design; Enzyme Inhibitors; Female; Male; Molecular Structure; Pyrroles; Rats; Rats, Inbred F344; Stereoisomerism; Structure-Activity Relationship; Tetrazoles | 2010 |
A diverse series of substituted benzenesulfonamides as aldose reductase inhibitors with antioxidant activity: design, synthesis, and in vitro activity.
Topics: Aldehyde Reductase; Animals; Antioxidants; Benzene Derivatives; Drug Design; Female; Free Radical Scavengers; In Vitro Techniques; Lipid Peroxidation; Male; Rats; Rats, Inbred F344; Stereoisomerism; Structure-Activity Relationship; Sulfonamides | 2010 |
Synthesis of derivatives of the keto-pyrrolyl-difluorophenol scaffold: some structural aspects for aldose reductase inhibitory activity and selectivity.
Topics: Aldehyde Reductase; Animals; Enzyme Inhibitors; Female; Male; Phenol; Protein Binding; Pyrroles; Rats | 2013 |
Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation.
Topics: Aldehyde Reductase; Animals; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Jejunum; Lenses; Male; Models, Molecular; Molecular Structure; Phenols; Pyrroles; Rats; Rats, Wistar; Sorbitol; Structure-Activity Relationship | 2014 |
Synthesis, characterization, hypoglycemic and aldose reductase inhibition activity of arylsulfonylspiro[fluorene-9,5'-imidazolidine]-2',4'-diones.
Topics: Aldehyde Reductase; Animals; Enzyme Inhibitors; Hypoglycemic Agents; Imidazolidines; Mice; Mice, Inbred BALB C; Molecular Docking Simulation | 2015 |
Enhancing activity and selectivity in a series of pyrrol-1-yl-1-hydroxypyrazole-based aldose reductase inhibitors: The case of trifluoroacetylation.
Topics: Acetylation; Aldehyde Reductase; Animals; Enzyme Inhibitors; Lens, Crystalline; Pyrazoles; Pyrroles; Rats; Sensitivity and Specificity; Sorbitol; Trifluoroacetic Acid | 2017 |
Inhibition of hexonate dehydrogenase and aldose reductase from bovine retina by sorbinil, statil, M79175 and valproate.
Topics: Aldehyde Reductase; Animals; Carbohydrate Dehydrogenases; Cattle; Imidazoles; Imidazolidines; In Vitro Techniques; Kinetics; Male; Molecular Conformation; Phthalazines; Pyridazines; Retina; Sugar Alcohol Dehydrogenases; Valproic Acid; Vitamin K | 1986 |
Inhibition of aldehyde reductases.
Topics: Alcohol Dehydrogenase; Animals; Imidazoles; Imidazolidines; Kinetics; Phenobarbital; Valproic Acid | 1987 |