valproic acid has been researched along with sodium oxybate in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (51.85) | 18.7374 |
| 1990's | 7 (25.93) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 1 (3.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bernasconi, R; Bittiger, H; Lauber, J; Leonhardt, T; Marescaux, C; Martin, P; Reymann, N; Rubio, V; Vergnes, M | 1 |
| Maitre, M; Vayer, P | 1 |
| Gobaille, S; Maitre, M; Mandel, P; Vayer, P | 1 |
| Alberti, KG; Dick, DJ; Sherratt, HS; Turnbull, DM; Wilson, L | 1 |
| Duncan, CC; Mirsky, AF; Myslobodsky, MS | 1 |
| Kaufman, EE; Nelson, T | 1 |
| Charlier, B; Maitre, M; Mandel, P; Vayer, P | 1 |
| Kaufman, EE; Miller, D; Nelson, T; Stadlan, N | 1 |
| Gibson, KM; Nyhan, WL; Pattarelli, PP | 1 |
| Cash, CD; Maitre, M; Vayer, P | 1 |
| Baltassat, P; Cotte, J; Divry, P; Duran, M; Hermier, M; Rolland, MO; Wadman, SK | 1 |
| Garbutt, JC; van Kammen, DP | 1 |
| Bearden, LJ; Healey, CT; Pegram, GV; Snead, OC | 1 |
| Ostrovskaia, RU; Popova, NK | 1 |
| Ostrovskaia, RU; Ratnikov, VI; Riabinina, NE | 1 |
| Chapman, AG | 1 |
| Baba, H; Ono, K; Sugai, S | 1 |
| Bernasconi, R; Bittiger, H; De Barry, J; Marescaux, C; Mathivet, P | 1 |
| Hechler, V; Maitre, M; Ratomponirina, C | 1 |
| Caffarra, P; Chiodera, P; Coiro, V; Saccani, A; Scaglioni, A; Volpi, R | 1 |
| Andriamampandry, C; Kemmel, V; Maitre, M; Mark, J; Perard, A; Siffert, JC; Taleb, O | 1 |
| David, J; Joseph, T; Kumaresan, S | 1 |
| Brady, KT; Malcolm, R; Myrick, H | 1 |
| David, J; Joseph, T; Subramanyam, K | 1 |
| Desmond, JC; Gui, D; Koeffler, HP; Kumagai, T; Miyakawa, I; Said, JW; Takai, N; Whittaker, S | 1 |
| Choi, HC; Choi, SY; Kang, TC; Kim, DS; Kim, JE; Kim, YI; Kwak, SE; Kwon, OS; Song, HK | 1 |
| Fricke, A; Mahlknecht, U; Ong, MF; Purrucker, JC; Rübe, C; Rübe, CE | 1 |
5 review(s) available for valproic acid and sodium oxybate
| Article | Year |
|---|---|
Petit mal epilepsy: a review and integration of recent information.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Brain; Cognition; Dementia; Electroencephalography; Electrophysiology; Epilepsy, Absence; Evoked Potentials; gamma-Aminobutyric Acid; Humans; Motor Skills; Norepinephrine; Prognosis; Sensation; Sodium Oxybate; Valproic Acid | 1986 |
Is the anticonvulsant mechanism of valproate linked to its interaction with the cerebral gamma-hydroxybutyrate system?
Topics: Animals; Brain; Hydroxybutyrates; Sodium Oxybate; Valproic Acid | 1988 |
The interaction between GABA and dopamine: implications for schizophrenia.
Topics: Animals; Antipsychotic Agents; Baclofen; Brain Chemistry; Catalepsy; Dopamine; gamma-Aminobutyric Acid; Humans; Motor Activity; Neural Pathways; Neurons; Rats; Receptors, Dopamine; Rotation; Schizophrenia; Sodium Oxybate; Stereotyped Behavior; Valproic Acid | 1983 |
[Sodium valproate--current status of pharmacological research].
Topics: Animals; Calcium; Dopamine; gamma-Aminobutyric Acid; Humans; Ion Channels; Rats; Serotonin; Sodium Oxybate; Valproic Acid | 1994 |
New developments in the pharmacotherapy of alcohol dependence.
Topics: Acamprosate; Adjuvants, Anesthesia; Alcohol Deterrents; Alcoholism; Anticonvulsants; Buspirone; Carbamazepine; Drug Therapy; Ethanol; Humans; Naltrexone; Narcotic Antagonists; Randomized Controlled Trials as Topic; Ritanserin; Serotonin Agents; Sodium Oxybate; Substance Withdrawal Syndrome; Taurine; Valproic Acid; Vigabatrin | 2001 |
1 trial(s) available for valproic acid and sodium oxybate
| Article | Year |
|---|---|
Different control mechanisms of growth hormone (GH) secretion between gamma-amino- and gamma-hydroxy-butyric acid: neuroendocrine evidence in Parkinson's disease.
Topics: Aged; Baclofen; GABA Agents; GABA Agonists; gamma-Aminobutyric Acid; Growth Hormone; Humans; Male; Middle Aged; Parkinson Disease; Sodium Oxybate; Valproic Acid | 1997 |
21 other study(ies) available for valproic acid and sodium oxybate
| Article | Year |
|---|---|
Experimental absence seizures: potential role of gamma-hydroxybutyric acid and GABAB receptors.
Topics: 4-Butyrolactone; Animals; Baclofen; Brain; Cyclic GMP; Disease Models, Animal; Epilepsy, Absence; GABA-A Receptor Antagonists; Male; Organophosphorus Compounds; Rats; Rats, Inbred Strains; Receptors, GABA-A; Reference Values; Reproducibility of Results; Sodium Oxybate; Valproic Acid | 1992 |
Gamma-hydroxybutyrate stimulation of the formation of cyclic GMP and inositol phosphates in rat hippocampal slices.
Topics: Animals; Cyclic GMP; Ethosuximide; Hippocampus; Hydroxybutyrates; Inositol Phosphates; Kinetics; Nalorphine; Naloxone; Pentazocine; Rats; Rats, Inbred Strains; Sodium Oxybate; Sugar Phosphates; Trimethadione; Valproic Acid | 1989 |
3'-5' cyclic-guanosine monophosphate increase in rat brain hippocampus after gamma-hydroxybutyrate administration. Prevention by valproate and naloxone.
Topics: Animals; Cyclic GMP; Hippocampus; Hydroxybutyrates; Kinetics; Male; Naloxone; Rats; Rats, Inbred Strains; Sodium Oxybate; Valproic Acid | 1987 |
Valproate causes metabolic disturbance in normal man.
Topics: Acetoacetates; Administration, Oral; Blood Glucose; Chemical and Drug Induced Liver Injury; Humans; Injections, Intravenous; Lactates; Lactic Acid; Male; Pyruvates; Pyruvic Acid; Sodium Oxybate; Valproic Acid | 1986 |
Evidence for the participation of a cytosolic NADP+-dependent oxidoreductase in the catabolism of gamma-hydroxybutyrate in vivo.
Topics: Animals; Brain; GABA Antagonists; gamma-Aminobutyric Acid; Glucuronates; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; Keto Acids; Kidney; Male; Muscles; Phenylacetates; Rats; Rats, Inbred Strains; Sodium Oxybate; Sodium Salicylate; Valproic Acid | 1987 |
Effect of anticonvulsant drugs on gamma-hydroxybutyrate release from hippocampal slices: inhibition by valproate and ethosuximide.
Topics: Animals; Ethosuximide; Hippocampus; Hydroxybutyrates; Pentobarbital; Potassium; Rats; Rats, Inbred Strains; Sodium Oxybate; Trimethadione; Valproic Acid; Verapamil; Veratridine | 1987 |
Oxidation of gamma-hydroxybutyrate to succinic semialdehyde by a mitochondrial pyridine nucleotide-independent enzyme.
Topics: Animals; Brain; Carbon Dioxide; Cytosol; gamma-Aminobutyric Acid; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; Immunoassay; Kidney; Male; Mitochondria; NAD; NADP; Oxidation-Reduction; Rats; Rats, Inbred Strains; Sodium Oxybate; Valproic Acid | 1988 |
Oxidation of [U-14C]succinic semialdehyde in cultured human lymphoblasts: measurement of residual succinic semialdehyde dehydrogenase activity in 11 patients with 4-hydroxybutyric aciduria.
Topics: Aldehyde Oxidoreductases; Carbon Dioxide; Cells, Cultured; Child; Child, Preschool; Female; gamma-Aminobutyric Acid; Humans; Hydroxybutyrates; Infant; Kinetics; Lactates; Lactic Acid; Lymphocytes; Male; Malonates; Oxidation-Reduction; Sodium Oxybate; Succinate-Semialdehyde Dehydrogenase; Succinates; Succinic Acid; Valproic Acid | 1988 |
A new patient with 4-hydroxybutyric aciduria, a possible defect of 4-aminobutyrate metabolism.
Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Humans; Hydroxybutyrate Dehydrogenase; Hydroxybutyrates; Male; Sodium Oxybate; Valproic Acid | 1983 |
Antagonism of gamma-hydroxybutyric acid-induced frequency shifts in the cortical EEG of rats by dipropylacetate.
Topics: Animals; Cerebral Cortex; Electroencephalography; Hydroxybutyrates; Male; Rats; Sodium Oxybate; Valproic Acid | 1980 |
[Effect of gamma-aminobutyric and gamma-hydroxybutyric acids on the arousal of susliks from hibernation].
Topics: Aminooxyacetic Acid; Animals; gamma-Aminobutyric Acid; Hibernation; Hydroxybutyrates; Male; Sciuridae; Semicarbazides; Sodium Oxybate; Valproic Acid | 1984 |
[Effect of GABA-ergic substances on humoral immunity].
Topics: Animals; Antibody Formation; gamma-Aminobutyric Acid; Immunization; Immunosuppressive Agents; Mice; Mice, Inbred CBA; Sodium Oxybate; Spleen; Valproic Acid | 1982 |
A new chronic model of spontaneous nonconvulsive generalized seizures.
Topics: 4-Butyrolactone; Animals; Cerebral Cortex; Corpus Callosum; Electroencephalography; Epilepsy, Absence; Epilepsy, Generalized; Ethosuximide; Evoked Potentials; Injections, Intraperitoneal; Male; Phenytoin; Rats; Rats, Wistar; Seizures; Sodium Oxybate; Valproic Acid | 1993 |
Binding characteristics of gamma-hydroxybutyric acid as a weak but selective GABAB receptor agonist.
Topics: Animals; Anticonvulsants; Baclofen; Binding, Competitive; Brain Chemistry; Ethosuximide; GABA Agonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Guanylyl Imidodiphosphate; In Vitro Techniques; Male; Organophosphorus Compounds; Radioligand Assay; Rats; Rats, Wistar; Receptors, GABA-B; Sodium Oxybate; Valproic Acid | 1997 |
gamma-Hydroxybutyrate conversion into GABA induces displacement of GABAB binding that is blocked by valproate and ethosuximide.
Topics: 4-Aminobutyrate Transaminase; Animals; Binding Sites; Brain; Enzyme Inhibitors; Ethosuximide; gamma-Aminobutyric Acid; Hydroxybutyrate Dehydrogenase; In Vitro Techniques; Male; Rats; Rats, Wistar; Sodium Oxybate; Valproic Acid | 1997 |
Neurochemical and electrophysiological evidence for the existence of a functional gamma-hydroxybutyrate system in NCB-20 neurons.
Topics: Animals; Binding Sites; Biological Transport; Brain; Calcium; Calcium Channels; Cell Line; Cricetinae; Cricetulus; Hybridomas; Hydroxybutyrate Dehydrogenase; Immunohistochemistry; Kinetics; Membrane Potentials; Mice; Neuroblastoma; Neurons; Patch-Clamp Techniques; Rats; Sodium Oxybate; Valproic Acid | 1998 |
Comparative profiles of sodium valproate and ethosuximide on electro-behavioural correlates in gamma-hydroxybutyrate and pentylenetetrazol induced absence seizures in rats.
Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Electroencephalography; Epilepsy, Absence; Ethosuximide; Male; Pentylenetetrazole; Rats; Rats, Wistar; Sodium Oxybate; Species Specificity; Valproic Acid | 2000 |
Interaction of flunarizine with sodium valproate or ethosuximide in gamahydroxybutyrate induced absence seizures in rats.
Topics: Animals; Anticonvulsants; Calcium Channel Blockers; Disease Models, Animal; Drug Interactions; Drug Synergism; Electroencephalography; Epilepsy, Absence; Ethosuximide; Flunarizine; Male; Rats; Rats, Wistar; Sodium Oxybate; Valproic Acid | 2001 |
Histone deacetylase inhibitors have a profound antigrowth activity in endometrial cancer cells.
Topics: Agar; Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cadherins; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Chromatin; Cyclin D1; Cyclin D2; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Dose-Response Relationship, Drug; Endometrial Neoplasms; Enzyme Inhibitors; Female; Flow Cytometry; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; In Situ Nick-End Labeling; Mice; Mice, Nude; Precipitin Tests; Proto-Oncogene Proteins c-bcl-2; S Phase; Sodium Oxybate; Time Factors; Tumor Suppressor Proteins; Valproic Acid; Vorinostat | 2004 |
Anti-glutamatergic effect of riluzole: comparison with valproic acid.
Topics: Animals; Anticonvulsants; Dentate Gyrus; Disease Models, Animal; Epilepsy, Absence; Excitatory Postsynaptic Potentials; Limbic System; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Riluzole; Seizures; Sodium Oxybate; Status Epilepticus; Valproic Acid; Vesicular Glutamate Transport Protein 1 | 2007 |
HDAC inhibition radiosensitizes human normal tissue cells and reduces DNA Double-Strand Break repair capacity.
Topics: Benzamides; Cell Proliferation; DNA Breaks, Double-Stranded; DNA Repair; Dose-Response Relationship, Radiation; Fibroblasts; Histone Deacetylases; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Pyridines; Signal Transduction; Sodium Oxybate; Time Factors; Valproic Acid; Vorinostat | 2010 |