Compounds > valproic acid

valproic acid and serine

valproic acid has been researched along with serine in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's6 (50.00)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Kamoun, P; Parvy, P1
De Sarno, P; Eom, TY; Jope, RS; Roh, MS; Roth, KA; Zmijewska, AA1
Furuichi, T; Tomomura, M1
Agata, N; Agawa-Ohta, M; Akiyama, M; Ida, H; Iwase, S; Kawano, T; Mikami-Terao, Y; Yamada, H; Yanagisawa, T1
Caruso, JA; Deranieh, RM; Greenberg, ML; He, Q1
Cho, DH; Han, SH; Hwang, S; Ja Kwon, K; Jo, I; Jong Won, K; Joo Lee, E; Kim, YH; Lee, SH; Park, JH; Song, KH; Young Shin, C1
Chu, SL; Ho, YL; Huang, PT; Liou, HH; Tsai, HJ; Yu, WH1
Fusté, M; Gill, G; Haro, JM; Meléndez-Pérez, I; Pinacho, R; Ramos, B; Saia, G; Villalta-Gil, V1
Chu, Z; Dang, YH; Liang, XP; Liu, P; Xing, B; Zhao, Y1
Fukuyama, K; Murata, M; Okada, M; Okubo, R; Shiroyama, T1
Chen, J; Jiang, H; Jiang, X; Lin, Z; Liu, Y; Lu, J; Shang, H; Shi, J; Song, L; Wang, X; Wu, S; Yan, D; Zhang, H1
Cheng, H; Dong, XW; Jian, J; Li, EY; Li, HL; Li, LG; Li, S; Yin, BQ; Zhao, PJ; Zhao, YH; Zheng, RJ1

Other Studies

12 other study(ies) available for valproic acid and serine

ArticleYear
[Effect of n-dipropyl-acetate on the elimination of urinary amino acids].
    Helvetica paediatrica acta, 1978, Volume: 33, Issue:4-5

    Topics: Alanine; Amino Acids; Child; Glutamates; Glutamine; Glycine; Histidine; Humans; Male; Ornithine; Serine; Valproic Acid

1978
Hypoxia activates glycogen synthase kinase-3 in mouse brain in vivo: protection by mood stabilizers and imipramine.
    Biological psychiatry, 2005, Feb-01, Volume: 57, Issue:3

    Topics: Animals; Anticonvulsants; Antidepressive Agents, Tricyclic; Brain; Carbon Dioxide; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Glycogen Synthase Kinase 3; Hypoxia; Imipramine; Immunoblotting; Immunohistochemistry; Lithium; Male; Mice; Mice, Inbred C57BL; Nitrogen; Phosphorylation; Serine; Time Factors; Valproic Acid

2005
Apoptosis-associated tyrosine kinase (AATYK) has differential Ca2+-dependent phosphorylation states in response to survival and apoptotic conditions in cerebellar granule cells.
    The Journal of biological chemistry, 2005, Oct-21, Volume: 280, Issue:42

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Calcium; Calcium Channels; Cell Movement; Cell Survival; Cells, Cultured; Cerebellum; Dose-Response Relationship, Drug; Enzyme Inhibitors; Lithium; Mice; Mutation; Phosphorylation; Plasmids; Potassium; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-jun; Serine; Valproic Acid

2005
Histone deacetylase inhibitors valproic acid and depsipeptide sensitize retinoblastoma cells to radiotherapy by increasing H2AX phosphorylation and p53 acetylation-phosphorylation.
    International journal of oncology, 2010, Volume: 37, Issue:4

    Topics: Acetylation; Apoptosis; Caspase 3; Cell Cycle Proteins; Cell Line, Tumor; Depsipeptides; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Humans; Nuclear Proteins; Phosphorylation; Poly(ADP-ribose) Polymerases; Protein Processing, Post-Translational; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Radiation-Sensitizing Agents; Retinoblastoma; Serine; Tumor Suppressor Protein p53; Valproic Acid

2010
Phosphorylation regulates myo-inositol-3-phosphate synthase: a novel regulatory mechanism of inositol biosynthesis.
    The Journal of biological chemistry, 2013, Sep-13, Volume: 288, Issue:37

    Topics: Amino Acid Sequence; Binding Sites; Catalysis; Escherichia coli; Gene Expression Regulation, Enzymologic; Humans; Inositol; Intramolecular Lyases; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Phospholipids; Phosphoproteins; Phosphorylation; Protein Binding; Protein Conformation; Protein Processing, Post-Translational; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Serine; Valproic Acid

2013
Valproic acid increases NO production via the SH-PTP1-CDK5-eNOS-Ser(116) signaling cascade in endothelial cells and mice.
    Free radical biology & medicine, 2014, Volume: 76

    Topics: Animals; Anticonvulsants; Aorta; Blotting, Western; Cattle; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cyclin-Dependent Kinase 5; Endothelium, Vascular; Fluorescent Antibody Technique; Immunoenzyme Techniques; Immunoprecipitation; Male; Mice; Mice, Inbred ICR; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphorylation; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; SH2 Domain-Containing Protein Tyrosine Phosphatases; Signal Transduction; Surface Plasmon Resonance; Valproic Acid

2014
The Phosphorylation State of GSK3β Serine 9 Correlated to the Development of Valproic Acid-Associated Fetal Cardiac Teratogenicity, Fetal VPA Syndrome, Rescued by Folic Acid Administration.
    Cardiovascular toxicology, 2016, Volume: 16, Issue:1

    Topics: Animals; Animals, Genetically Modified; Anticonvulsants; Bradycardia; Cell Proliferation; Dose-Response Relationship, Drug; Embryo, Nonmammalian; Female; Folic Acid; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Heart Defects, Congenital; Heart Ventricles; Male; Myocytes, Cardiac; Phosphorylation; Serine; Valproic Acid; Vitamins; Zebrafish

2016
Phosphorylation of transcription factor specificity protein 4 is increased in peripheral blood mononuclear cells of first-episode psychosis.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Animals; Antipsychotic Agents; Benzodiazepines; Cells, Cultured; Cross-Sectional Studies; Female; Humans; Lithium; Male; Models, Biological; Neurons; Olanzapine; Phosphorylation; Pilot Projects; Psychotic Disorders; Rats; Serine; Sp4 Transcription Factor; Valproic Acid; Young Adult

2015
Valproate Inhibits Methamphetamine Induced Hyperactivity via Glycogen Synthase Kinase 3β Signaling in the Nucleus Accumbens Core.
    PloS one, 2015, Volume: 10, Issue:6

    Topics: Animals; Behavior, Animal; Central Nervous System Stimulants; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hyperkinesis; Male; Methamphetamine; Microinjections; Motor Activity; Nucleus Accumbens; Phosphorylation; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Valproic Acid

2015
Activation of Astroglial Connexin is Involved in Concentration-Dependent Double-Edged Sword Clinical Action of Clozapine.
    Cells, 2020, 02-11, Volume: 9, Issue:2

    Topics: Antipsychotic Agents; Astrocytes; Cell Membrane; Clozapine; Connexin 43; Glutamic Acid; Humans; Myocarditis; Schizophrenia; Serine; Valproic Acid

2020
Alterations of serine racemase expression determine proliferation and differentiation of neuroblastoma cells.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022, Volume: 36, Issue:9

    Topics: Animals; Cell Differentiation; Cell Proliferation; Mice; Mice, Nude; Neuroblastoma; Racemases and Epimerases; RNA, Small Interfering; Serine; Valproic Acid

2022
Mouse nerve growth factor suppresses neuronal apoptosis in valproic acid-induced autism spectrum disorder rats by regulating the phosphoinositide-3-kinase/serine/threonine kinase signaling pathway.
    Pharmacogenetics and genomics, 2023, 07-01, Volume: 33, Issue:5

    Topics: Animals; Apoptosis; Autism Spectrum Disorder; Disease Models, Animal; Humans; Mice; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phosphatidylinositols; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Serine; Signal Transduction; Valproic Acid

2023