valproic acid has been researched along with sec-butyl-propylacetamide in 14 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (7.14) | 29.6817 |
| 2010's | 13 (92.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bialer, M; Devor, M; Kaufmann, D; Shimshoni, JA; Yagen, B | 1 |
| Bialer, M; Hen, N; Yagen, B | 1 |
| Bialer, M; Bibi, D; Mawasi, H | 1 |
| Alex, AB; Bialer, M; Hen, N; Kaufmann, D; McDonough, JH; Pollock, A; Shekh-Ahmad, T; Stables, JP; White, HS; Wilcox, KS; Yagen, B | 1 |
| Bialer, M; Dudek, FE; Hen, N; Kaufmann, D; Nelson, C; Pouliot, W; Ricks, K; Roach, B; Shekh-Ahmad, T; Yagen, B | 1 |
| Bialer, M; Nanau, RM; Neuman, MG; Shekh-Ahmad, T; Yagen, B | 1 |
| Bialer, M; Finnell, RH; Hen, N; McDonough, JH; Shekh-Ahmad, T; Wlodarczyk, B; Yagen, B | 1 |
| Bialer, M; Hen, N; McDonough, JH; Shekh-Ahmad, T; Yagen, B | 1 |
| Bar-Klein, G; Bialer, M; Eisenkraft, A; Friedman, A; Hubary, Y; Kamintsky, L; Saar-Ashkenazy, R; Shekh-Ahmad, T; Shrot, S; Stetlander, L; Swissa, E | 1 |
| Bialer, M; Finnell, RH; Mawasi, H; Shekh-Ahmad, T; Wlodarczyk, BJ | 1 |
| Bialer, M; Mawasi, H; McDonough, JH; Shekh-Ahmad, T; Yagen, B | 1 |
| Bates, EA; Bialer, M; Brennan, KC; Kaufmann, D; Saunders, GH; White, HS; Wilcox, K; Yagen, B | 1 |
| Bialer, M; Bibi, D; Blotnik, S; Mawasi, H; Shaul, C; Shekh-Ahmad, T | 1 |
| Bialer, M; Brennan, KC; Devor, M; Kaufmann, D; Smith, MD; West, PJ; White, HS; Yagen, B | 1 |
1 review(s) available for valproic acid and sec-butyl-propylacetamide
| Article | Year |
|---|---|
The potential of sec-butylpropylacetamide (SPD) and valnoctamide and their individual stereoisomers in status epilepticus.
Topics: Amides; Animals; Anticonvulsants; Humans; Status Epilepticus; Stereoisomerism; Valproic Acid | 2015 |
13 other study(ies) available for valproic acid and sec-butyl-propylacetamide
| Article | Year |
|---|---|
Synthesis and evaluation of antiallodynic and anticonvulsant activity of novel amide and urea derivatives of valproic acid analogues.
Topics: Amides; Animals; Anticonvulsants; Electroshock; Isomerism; Male; Mice; Pain; Pentylenetetrazole; Rats; Rats, Sprague-Dawley; Seizures; Spinal Nerves; Urea; Valproic Acid | 2009 |
Syntheses and evaluation of anticonvulsant activity of novel branched alkyl carbamates.
Topics: Animals; Anticonvulsants; Carbamates; Male; Mice; Neurotoxicity Syndromes; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Structure-Activity Relationship | 2012 |
Design and comparative anticonvulsant activity assessment of CNS-active alkyl-carbamoyl imidazole derivatives.
Topics: Animals; Anticonvulsants; Blood-Brain Barrier; Carbamates; Electroshock; Imidazoles; Male; Mice; Rats, Sprague-Dawley; Seizures; Structure-Activity Relationship | 2016 |
A new derivative of valproic acid amide possesses a broad-spectrum antiseizure profile and unique activity against status epilepticus and organophosphate neuronal damage.
Topics: Amides; Animals; Anticonvulsants; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Guinea Pigs; Hippocampus; Male; Mice; Neurons; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Seizures; Status Epilepticus; Time Factors; Treatment Outcome; Valproic Acid | 2012 |
A comparative electrographic analysis of the effect of sec-butyl-propylacetamide on pharmacoresistant status epilepticus.
Topics: Amides; Animals; Anticonvulsants; Cerebral Cortex; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Male; Pentobarbital; Pilocarpine; Rats; Rats, Sprague-Dawley; Status Epilepticus; Valproic Acid | 2013 |
Valproic acid derivatives signal for apoptosis and repair in vitro.
Topics: Amides; Apoptosis; Cell Line, Tumor; Cell Survival; Cells, Cultured; DNA Repair; Drug Hypersensitivity Syndrome; Gene Expression; Hepatocytes; Humans; Inflammation; Interferon-gamma; Interleukin-1; Interleukin-6; Keratin-18; Lymphocytes; Signal Transduction; Tumor Necrosis Factor-alpha; Valproic Acid | 2013 |
Stereoselective pharmacodynamic and pharmacokinetic analysis of sec-Butylpropylacetamide (SPD), a new CNS-active derivative of valproic acid with unique activity against status epilepticus.
Topics: Acetamides; Amides; Animals; Anticonvulsants; Disease Models, Animal; Rats; Soman; Status Epilepticus; Stereoisomerism; Teratogens; Valproic Acid | 2013 |
Valnoctamide and sec-butyl-propylacetamide (SPD) for acute seizures and status epilepticus.
Topics: Acute Disease; Amides; Animals; Anticonvulsants; Disease Models, Animal; Guinea Pigs; Humans; Rats; Seizures; Status Epilepticus; Treatment Outcome; Valproic Acid | 2013 |
sec-Butyl-propylacetamide (SPD) and two of its stereoisomers rapidly terminate paraoxon-induced status epilepticus in rats.
Topics: Amides; Animals; Anticonvulsants; Disease Models, Animal; Electroencephalography; Insecticides; Male; Paraoxon; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Status Epilepticus; Stereoisomerism; Treatment Outcome; Valproic Acid | 2014 |
Pharmacodynamic and pharmacokinetic analysis of CNS-active constitutional isomers of valnoctamide and sec-butylpropylacetamide--Amide derivatives of valproic acid.
Topics: Amides; Animals; Anticonvulsants; Female; Isomerism; Male; Mice; Mice, Transgenic; Rats; Rats, Sprague-Dawley; Seizures; Valproic Acid | 2015 |
sec-Butylpropylacetamide (SPD) has antimigraine properties.
Topics: Amides; Animals; Anticonvulsants; Cell Line, Tumor; Cells, Cultured; Cerebral Cortex; Cortical Spreading Depression; Male; Mice; Mice, Inbred C57BL; Migraine Disorders; Valproic Acid | 2016 |
Pharmacokinetic-Pharmacodynamic Correlation and Brain Penetration of sec-Butylpropylacetamide, a New CNS Drug Possessing Unique Activity against Status Epilepticus.
Topics: Administration, Intravenous; Amides; Animals; Anticonvulsants; Benzodiazepines; Brain; Central Nervous System Agents; Gas Chromatography-Mass Spectrometry; Injections, Intraperitoneal; Rats; Status Epilepticus; Valproic Acid | 2016 |
sec-Butylpropylacetamide (SPD), a new amide derivative of valproic acid for the treatment of neuropathic and inflammatory pain.
Topics: Amides; Amines; Analgesics; Animals; Cyclohexanecarboxylic Acids; Disease Models, Animal; Gabapentin; gamma-Aminobutyric Acid; Inflammation; Male; Mice; Neuralgia; Pain; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Valproic Acid | 2017 |