valproic acid and riluzole

valproic acid has been researched along with riluzole in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (41.18)29.6817
2010's10 (58.82)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Bruno-Blanch, L; Gálvez, J; García-Domenech, R1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Borowicz, KK; Czuczwar, SJ; Drelewska, E; Rwiader, M1
Choi, HC; Choi, SY; Kang, TC; Kim, DS; Kim, JE; Kim, YI; Kwak, SE; Kwon, OS; Song, HK1
Lamas, JA; Reboreda, A; Ribeiro, SJ; Romero, M; Sánchez, E1
Drevets, WC; Henter, ID; Manji, HK; Salvadore, G; Zarate, CA1
Veenstra-VanderWeele, J1
Eisenach, JC; Hayashida, K; Hobo, S1
Fernandez, L; Gurevich, M; Hurst, LC; Komatsu, DE1
Mielke, D; Ninkovic, M; Rohde, V; Sachkova, A; Schatlo, B; Sperling, S1

Reviews

3 review(s) available for valproic acid and riluzole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Early intervention in bipolar disorder, part II: therapeutics.
    Early intervention in psychiatry, 2008, Volume: 2, Issue:3

    Topics: Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Brain; Early Diagnosis; Humans; Lamotrigine; Lithium Compounds; Riluzole; Triazines; Valproic Acid

2008
Emerging Strategies on Adjuvant Therapies for Nerve Recovery.
    The Journal of hand surgery, 2018, Volume: 43, Issue:4

    Topics: Absorbable Implants; Allografts; Autografts; Calcium Channel Blockers; Erythropoietin; Gabapentin; Humans; Immunosuppressive Agents; Lithium Compounds; Nerve Regeneration; Neuroprotective Agents; Neurosurgical Procedures; Peripheral Nerve Injuries; Peripheral Nerves; Recovery of Function; Riluzole; Stem Cell Transplantation; Valproic Acid; Veins; Wallerian Degeneration

2018

Other Studies

14 other study(ies) available for valproic acid and riluzole

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Topological virtual screening: a way to find new anticonvulsant drugs from chemical diversity.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Anticonvulsants; Computer Simulation; Databases, Factual; Discriminant Analysis; Drug Design; Molecular Structure; Quantitative Structure-Activity Relationship

2003
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
    Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24

    Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility

2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Interactions between riluzole and conventional antiepileptic drugs -- a comparison of results obtained in the subthreshold method and isobolographic analysis.
    Journal of neural transmission (Vienna, Austria : 1996), 2004, Volume: 111, Issue:12

    Topics: Animals; Anticonvulsants; Carbamazepine; Disease Models, Animal; Drug Interactions; Electroshock; Male; Memory; Mice; Motor Activity; Phenobarbital; Phenytoin; Riluzole; Seizures; Valproic Acid

2004
Anti-glutamatergic effect of riluzole: comparison with valproic acid.
    Neuroscience, 2007, Jun-15, Volume: 147, Issue:1

    Topics: Animals; Anticonvulsants; Dentate Gyrus; Disease Models, Animal; Epilepsy, Absence; Excitatory Postsynaptic Potentials; Limbic System; Male; Pilocarpine; Rats; Rats, Sprague-Dawley; Riluzole; Seizures; Sodium Oxybate; Status Epilepticus; Valproic Acid; Vesicular Glutamate Transport Protein 1

2007
A riluzole- and valproate-sensitive persistent sodium current contributes to the resting membrane potential and increases the excitability of sympathetic neurones.
    Pflugers Archiv : European journal of physiology, 2009, Volume: 458, Issue:3

    Topics: Animals; Anticonvulsants; Cells, Cultured; Dose-Response Relationship, Drug; Ion Channel Gating; Membrane Potentials; Neurons; Rats; Rats, Sprague-Dawley; Riluzole; Sodium; Sodium Channels; Superior Cervical Ganglion; Sympathetic Nervous System; Valproic Acid

2009
Increase in valproic acid levels during riluzole treatment in an adolescent with autism.
    Journal of child and adolescent psychopharmacology, 2010, Volume: 20, Issue:2

    Topics: Adolescent; Autistic Disorder; Female; Humans; Riluzole; Valproic Acid

2010
Up-regulation of spinal glutamate transporters contributes to anti-hypersensitive effects of valproate in rats after peripheral nerve injury.
    Neuroscience letters, 2011, Sep-08, Volume: 502, Issue:1

    Topics: Analgesics; Animals; Disease Models, Animal; Drug Therapy, Combination; Excitatory Amino Acid Transporter 1; Excitatory Amino Acid Transporter 2; Hyperalgesia; Kainic Acid; Pain Threshold; Peripheral Nerve Injuries; Rats; Rats, Sprague-Dawley; Riluzole; Spinal Cord; Up-Regulation; Valproic Acid

2011
Combined Applications of Repurposed Drugs and Their Detrimental Effects on Glioblastoma Cells.
    Anticancer research, 2019, Volume: 39, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gene Expression Regulation, Neoplastic; Glioblastoma; Glycoproteins; Humans; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Riluzole; Temozolomide; Tranylcypromine; Valproic Acid; Xenograft Model Antitumor Assays

2019