valproic acid and resveratrol

valproic acid has been researched along with resveratrol in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (8.33)29.6817
2010's13 (54.17)24.3611
2020's9 (37.50)2.80

Authors

AuthorsStudies
Dansette, PM; Fontana, E; Poli, SM1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Forgione, M; Hailu, GS; Mai, A; Robaa, D; Rotili, D; Sippl, W1
Alfano, AI; Barone, S; Brindisi, M; Cassese, E; Summa, V1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Gray, SG1
Chen, KC; Hsieh, CL; Lin, PX; Peng, CC; Peng, RY1
Alka, K; Dolly, JO; Henehan, GT; Ryan, BJ1
Bambini-Junior, V; Della Flora Nunes, G; Fontes-Dutra, M; Gottfried, C; Michels, M; Mueller de Melo, G; Nogueira Freire, V; Riesgo, R; Zanatta, G1
Chen, Y; Hsieh, CL; Lin, PX; Peng, CC; Peng, RY1
Fuentes, JM; Gómez-Sánchez, R; González-Polo, RA; Pedro, JM; Pizarro-Estrella, E; Rodríguez-Arribas, M; Yakhine-Diop, SM1
Chen, H; Chen, J; Hardin, H; Harrison, AD; Larrain, C; Lloyd, RV; Yu, XM; Zhang, R1
Glasow, A; Kortmann, RD; Menzel, F; Patties, I1
Baldisserotto, B; Barreto, KP; Finamor, IA; Glanzner, WG; Gonçalves, PB; Ourique, GM; Pavanato, MA; Pês, TS; Saccol, EM1
Annunziato, L; Benarese, M; Cepparulo, P; Cuomo, O; Faggi, L; Lanzillotta, A; Mota, M; Parrella, E; Pignataro, G; Pizzi, M; Porrini, V; Spano, P; Tonin, P; Vinciguerra, A1
Bambini-Junior, V; Bauer-Negrini, G; Deckmann, I; Della-Flora Nunes, G; Fontes-Dutra, M; Gottfried, C; Hirsch, MM; Margis, R; Nunes, W; Rabelo, B; Riesgo, R1
Bambini-Junior, V; Bauer-Negrini, G; Della-Flora Nunes, G; Fontes-Dutra, M; Gottfried, C; Green, L; Hirsch, MM; Riesgo, R; Santos-Terra, J; Souza-Nunes, W1
Bambery, KR; Karagiannis, TC; Licciardi, PV; Mazarakis, N; Royce, SG; Samuel, CS; Snibson, KJ; Tobin, MJ; Ververis, K; Vongsvivut, J1
Bambini-Junior, V; Deckmann, I; Fontes-Dutra, M; Gama, CS; Gottfried, C; Paz, AVC; Santos-Terra, J; Schwingel, GB1
Chung, RS; Cole, NJ; De Luca, A; Guillemin, GJ; Laird, AS; Lee, A; Luu, L; Nicholson, GA; Robinson, KJ; Suddull, HJ; Tym, MC; Watchon, M; Yuan, KC1
Bankole, O; Bonafede, R; Mariotti, R; Muccilli, M; Parrella, E; Pizzi, M; Scambi, I; Turano, E1
Bauer-Negrini, G; Carello-Collar, G; Deckmann, I; Fontes-Dutra, M; Gottfried, C; Nunes, GD; Riesgo, R; Santos-Terra, J; Schwingel, GB1
Brum Schwingel, G; Calcagnotto, ME; Deckmann, I; Fontes-Dutra, M; Gottfried, C; Kazmierzak de Moraes, R; Rabelo, B; Righes Marafiga, J; Rockenbach, M; Santos-Terra, J; Vendramin Pasquetti, M1
Amiresmaili, S; Bashiri, H; Juybari, KB; Moslemizadeh, A; Sepehri, G; Shahrbabaki, SSV; Shamsi Meymandi, M; Tezerji, SS1

Reviews

5 review(s) available for valproic acid and resveratrol

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005
Lysine Deacetylase Inhibitors in Parasites: Past, Present, and Future Perspectives.
    Journal of medicinal chemistry, 2017, 06-22, Volume: 60, Issue:12

    Topics: Animals; Antiparasitic Agents; Drug Repositioning; Helminth Proteins; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Leishmania; Plasmodium; Protozoan Proteins; Schistosoma; Toxoplasma; Trypanosoma

2017
Chasing a Breath of Fresh Air in Cystic Fibrosis (CF): Therapeutic Potential of Selective HDAC6 Inhibitors to Tackle Multiple Pathways in CF Pathophysiology.
    Journal of medicinal chemistry, 2022, 02-24, Volume: 65, Issue:4

    Topics: Animals; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Histone Deacetylase 6; Humans; Signal Transduction

2022
Epigenetic treatment of neurological disease.
    Epigenomics, 2011, Volume: 3, Issue:4

    Topics: Alzheimer Disease; Butylamines; Cell Differentiation; Endoplasmic Reticulum Stress; Epigenesis, Genetic; Histone Code; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Huntington Disease; Hydroxamic Acids; Neurons; Phenylbutyrates; Protein Processing, Post-Translational; Resveratrol; Stilbenes; Valproic Acid; Vorinostat

2011
Is the Modulation of Autophagy the Future in the Treatment of Neurodegenerative Diseases?
    Current topics in medicinal chemistry, 2015, Volume: 15, Issue:21

    Topics: Animals; Autophagy; Disease Models, Animal; Food; Humans; Isothiocyanates; Lithium; Neurodegenerative Diseases; Resveratrol; Sirolimus; Spermidine; Stilbenes; Sulfoxides; Trehalose; Valproic Acid

2015

Other Studies

19 other study(ies) available for valproic acid and resveratrol

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Resveratrol and vitamin E rescue valproic acid-induced teratogenicity: the mechanism of action.
    Clinical and experimental pharmacology & physiology, 2014, Volume: 41, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Antioxidants; Chick Embryo; Glutathione; Reactive Oxygen Species; Resveratrol; Stilbenes; Teratogenesis; Valproic Acid; Vitamin E

2014
New inhibitors of the Kvβ2 subunit from mammalian Kv1 potassium channels.
    The international journal of biochemistry & cell biology, 2014, Volume: 55

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Binding, Competitive; Brain; Catechols; Cortisone; Kinetics; NADP; Oxidation-Reduction; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Protein Binding; Rats; Resveratrol; Rutin; Shaker Superfamily of Potassium Channels; Stilbenes; Valproic Acid

2014
Resveratrol prevents social deficits in animal model of autism induced by valproic acid.
    Neuroscience letters, 2014, Nov-07, Volume: 583

    Topics: Animals; Anti-Inflammatory Agents; Autistic Disorder; Female; Male; Maternal Exposure; Molecular Dynamics Simulation; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Resveratrol; Social Skills; Stilbenes; Valproic Acid

2014
The proteomic and genomic teratogenicity elicited by valproic acid is preventable with resveratrol and α-tocopherol.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: alpha-Tocopherol; Animals; Anticonvulsants; Betaine-Homocysteine S-Methyltransferase; Carrier Proteins; Chick Embryo; Chromatography, Liquid; Filamins; Gene Expression Regulation; Membrane Proteins; Myosin Light Chains; Phosphatidylethanolamine Binding Protein; Proteome; Resveratrol; Serum Albumin; Stilbenes; Tandem Mass Spectrometry; Teratogens; Thyroid Hormone-Binding Proteins; Thyroid Hormones; Valproic Acid

2014
Generation of Novel Thyroid Cancer Stem-Like Cell Clones: Effects of Resveratrol and Valproic Acid.
    The American journal of pathology, 2016, Volume: 186, Issue:6

    Topics: Animals; Antioxidants; Blotting, Western; Cell Culture Techniques; Cell Line, Tumor; Enzyme Inhibitors; Flow Cytometry; Heterografts; Humans; Mice; Mice, Nude; Neoplastic Stem Cells; Real-Time Polymerase Chain Reaction; Resveratrol; Stilbenes; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms; Valproic Acid

2016
Enhanced inhibition of clonogenic survival of human medulloblastoma cells by multimodal treatment with ionizing irradiation, epigenetic modifiers, and differentiation-inducing drugs.
    Journal of experimental & clinical cancer research : CR, 2016, 06-17, Volume: 35, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Azacitidine; Cell Differentiation; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cerebellar Neoplasms; Combined Modality Therapy; Decitabine; Dideoxynucleosides; Epigenesis, Genetic; Humans; Hydroxamic Acids; Medulloblastoma; Mice; Neurogenesis; Radiation-Sensitizing Agents; Resveratrol; Stilbenes; Treatment Outcome; Tretinoin; Valproic Acid; Vorinostat; Xenograft Model Antitumor Assays

2016
Resveratrol prevents oxidative damage and loss of sperm motility induced by long-term treatment with valproic acid in Wistar rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2016, Volume: 68, Issue:8

    Topics: Animals; Anticonvulsants; Antioxidants; Fertility; Genitalia, Male; Male; Oxidative Stress; Rats, Wistar; Resveratrol; Sperm Motility; Spermatozoa; Stilbenes; Testosterone; Valproic Acid

2016
Synergistic Association of Valproate and Resveratrol Reduces Brain Injury in Ischemic Stroke.
    International journal of molecular sciences, 2018, Jan-06, Volume: 19, Issue:1

    Topics: Acetylation; Animals; Bcl-2-Like Protein 11; Disease Models, Animal; Drug Synergism; Histone Deacetylase Inhibitors; Histones; Male; Mice; Mice, Inbred C57BL; Neurons; Neuroprotective Agents; Promoter Regions, Genetic; Protein Binding; Resveratrol; Stilbenes; Stroke; Transcription Factor RelA; Valproic Acid

2018
Behavioral alterations in autism model induced by valproic acid and translational analysis of circulating microRNA.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2018, Volume: 115

    Topics: Adolescent; Animals; Anticonvulsants; Antioxidants; Autistic Disorder; Behavior, Animal; Child; Child, Preschool; Circulating MicroRNA; Disease Models, Animal; Female; Humans; Male; Maternal Exposure; MicroRNAs; Pregnancy; Prenatal Exposure Delayed Effects; Protein Biosynthesis; Rats, Wistar; Resveratrol; Stilbenes; Valproic Acid

2018
Abnormal empathy-like pro-social behaviour in the valproic acid model of autism spectrum disorder.
    Behavioural brain research, 2019, 05-17, Volume: 364

    Topics: Animals; Autism Spectrum Disorder; Disease Models, Animal; Empathy; Female; Interpersonal Relations; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Resveratrol; Social Behavior; Valproic Acid

2019
Investigation of molecular mechanisms of experimental compounds in murine models of chronic allergic airways disease using synchrotron Fourier-transform infrared microspectroscopy.
    Scientific reports, 2020, 07-16, Volume: 10, Issue:1

    Topics: Animals; Anti-Asthmatic Agents; Asthma; Chronic Disease; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Hydroxamic Acids; Isothiocyanates; Mice; Mice, Inbred BALB C; Ovalbumin; Relaxin; Resveratrol; Spectroscopy, Fourier Transform Infrared; Sulfoxides; Synchrotrons; Treatment Outcome; Valproic Acid

2020
Resveratrol prevents long-term structural hippocampal alterations and modulates interneuron organization in an animal model of ASD.
    Brain research, 2021, 10-01, Volume: 1768

    Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Female; Hippocampus; Interneurons; Male; Neurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Resveratrol; Social Behavior; Stereotyped Behavior; Valproic Acid

2021
Sodium valproate increases activity of the sirtuin pathway resulting in beneficial effects for spinocerebellar ataxia-3 in vivo.
    Molecular brain, 2021, 08-20, Volume: 14, Issue:1

    Topics: Acetylation; Animals; Animals, Genetically Modified; Ataxin-3; Autophagy; Carbazoles; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Synergism; Genes, Reporter; HEK293 Cells; Histone Deacetylase Inhibitors; Histones; Humans; Machado-Joseph Disease; Peptides; Protein Processing, Post-Translational; Recombinant Fusion Proteins; Repressor Proteins; Resveratrol; Signal Transduction; Sirtuin 1; Sirtuins; Swimming; Trinucleotide Repeat Expansion; Valproic Acid; Zebrafish; Zebrafish Proteins

2021
Beneficial and Sexually Dimorphic Response to Combined HDAC Inhibitor Valproate and AMPK/SIRT1 Pathway Activator Resveratrol in the Treatment of ALS Mice.
    International journal of molecular sciences, 2022, Jan-19, Volume: 23, Issue:3

    Topics: AMP-Activated Protein Kinases; Amyotrophic Lateral Sclerosis; Animals; Disease Models, Animal; Female; Histone Deacetylase Inhibitors; Histones; Male; Mice; Mice, Transgenic; NF-kappa B; Resveratrol; Sirtuin 1; Superoxide Dismutase; Valproic Acid

2022
Resveratrol Prevents Cytoarchitectural and Interneuronal Alterations in the Valproic Acid Rat Model of Autism.
    International journal of molecular sciences, 2022, Apr-07, Volume: 23, Issue:8

    Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Disease Models, Animal; Female; Interneurons; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Resveratrol; Valproic Acid

2022
GABAergic synaptic transmission and cortical oscillation patterns in the primary somatosensory area of a valproic acid rat model of autism spectrum disorder.
    The European journal of neuroscience, 2023, Volume: 57, Issue:3

    Topics: Animals; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Female; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Resveratrol; Rodentia; Social Behavior; Somatosensory Cortex; Synaptic Transmission; Valproic Acid

2023
Ameliorating age-dependent effects of resveratrol on VPA-induced social impairments and anxiety-like behaviors in a rat model of neurodevelopmental disorder.
    Neurotoxicology, 2023, Volume: 96

    Topics: Animals; Anxiety; Autism Spectrum Disorder; Behavior, Animal; Disease Models, Animal; Female; Humans; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Resveratrol; Social Behavior; Valproic Acid

2023