Compounds > valproic acid

valproic acid and pyrimethamine

valproic acid has been researched along with pyrimethamine in 11 studies

Research

Studies (11)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (9.09)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (27.27)	29.6817
2010's	6 (54.55)	24.3611
2020's	1 (9.09)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Lombardo, F; Obach, RS; Waters, NJ	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Donnelly, CA; Lamberton, PH; Torrey, EF; Webster, JP	1
Donnelly, CA; Lamberton, PH; Webster, JP	1
Bassetti, M; Beltrame, A; Buonfrate, D; Crichiutti, G; Meroni, V; Venturini, S	1
Bax, HI; Burger, D; Colbers, A; Crespo, R; de Mendonça Melo, M; de Vries-Sluijs, TEMS; Gruters, RA; Hossain, T; Kan, TW; Katsikis, PD; Koch, BCP; Li, L; Lungu, C; Mahmoudi, T; Mesplède, T; Mueller, YM; Nouwen, JL; Overmars, RJ; Palstra, RJ; Papageorgiou, G; Prins, HAB; Rao, S; Rijnders, BJA; Rokx, C; Schurink, CAM; Stoszko, M; van de Vijver, DAMC; van Gorp, ECM; van Kampen, JJA; van Nood, E; Verbon, A	1

Reviews

1 review(s) available for valproic acid and pyrimethamine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for valproic acid and pyrimethamine

Article	Year
The BAF complex inhibitor pyrimethamine reverses HIV-1 latency in people with HIV-1 on antiretroviral therapy. Science advances, 2023, 03-17, Volume: 9, Issue:11 Topics: CD4-Positive T-Lymphocytes; HIV Infections; HIV-1; Humans; Pyrimethamine; RNA; Valproic Acid; Virus Activation; Virus Latency	2023

Other Studies

9 other study(ies) available for valproic acid and pyrimethamine

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Parasites as causative agents of human affective disorders? The impact of anti-psychotic, mood-stabilizer and anti-parasite medication on Toxoplasma gondii's ability to alter host behaviour. Proceedings. Biological sciences, 2006, Apr-22, Volume: 273, Issue:1589 Topics: Animals; Antimanic Agents; Antiprotozoal Agents; Antipsychotic Agents; Behavior, Animal; Cats; Dapsone; Haloperidol; Humans; Mood Disorders; Pyrimethamine; Rabbits; Rats; Toxoplasma; Toxoplasmosis, Animal; Valproic Acid	2006
Specificity of the Toxoplasma gondii-altered behaviour to definitive versus non-definitive host predation risk. Parasitology, 2008, Volume: 135, Issue:10 Topics: Animals; Behavior, Animal; Cats; Dapsone; Haloperidol; Pyrimethamine; Rats; Species Specificity; Toxoplasma; Toxoplasmosis, Animal; Valproic Acid	2008
Recurrent seizures during acute acquired toxoplasmosis in an immunocompetent traveller returning from Africa. Infection, 2016, Volume: 44, Issue:2 Topics: Adolescent; Antibodies, Protozoan; Anticonvulsants; Antiprotozoal Agents; Epilepsy; Ethiopia; Humans; Immunoglobulin G; Immunoglobulin M; Leucovorin; Male; Pyrimethamine; Recurrence; Seizures; Sulfadiazine; Toxoplasma; Toxoplasmosis; Travel; Treatment Outcome; Valproic Acid	2016