valproic acid and pyridoxine

valproic acid has been researched along with pyridoxine in 25 studies

Research

Studies (25)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (28.00)	18.7374
1990's	8 (32.00)	18.2507
2000's	4 (16.00)	29.6817
2010's	6 (24.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Campanini, T; Catalano, A; De Risio, C; Forino, V	1
Stone, WE	1
Coulthard, MG	1
Elmazar, MM; Nau, H; Thiel, R	1
Geddes, JW; Wood, JD	1
Matsuo, T	1
Friel, PN; Koch, KM; Levy, RH; Lockard, JS; Maris, DO	1
Cordero, JF; Oakley, GP	1
Appleton, RE	1
Arai, H; Imai, K; Kita, T; Kodaka, R; Mano, T; Matsuoka, T; Nagai, T; Okada, S; Suzuki, Y	1
Rantala, H; Tarkka, R; Uhari, M	1
Brandl, U; Siemes, H; Spohr, HL; Völger, S; Weschke, B	1
Ito, M	1
Fiehn, W; Kohl, B; Rieser, PA; Ringleb, P; Schwaninger, M; Walter-Sack, I; Winter, R	1
Kábová, R; Liptáková, S; Pometlová, M; Slamberová, R; Velísek, L	1
Ito, M; Seki, T; Takuma, Y	1
Artuch, R; Cardo, E; Colomé, C; Farré, C; Monrós, E; Pineda, M; Valls, C; Vilaseca, MA	1
Adams-Webber, T; Ashwal, S; Ballaban-Gill, K; Baram, TZ; Duchowny, M; Hirtz, D; Mackay, MT; Pellock, JM; Shields, WD; Shinnar, S; Snead, OC; Stephens, D; Weiss, SK; Wyllie, E	1
Apeland, T; Frøyland, ES; Kristensen, O; Mansoor, MA; Strandjord, RE	1

Reviews

4 review(s) available for valproic acid and pyridoxine

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug exposure during pregnancy: some epidemiologic considerations. Clinical obstetrics and gynecology, 1983, Volume: 26, Issue:2 Topics: Abnormalities, Drug-Induced; Benzodiazepines; Caffeine; Dicyclomine; Doxylamine; Drug Combinations; Epidemiologic Methods; Female; Humans; Hydantoins; Immunosuppressive Agents; Lithium; Lithium Carbonate; Phenothiazines; Pregnancy; Pyridoxine; Registries; Risk; Rubella Vaccine; Solvents; Spermatocidal Agents; Trimethadione; Valproic Acid	1983
A meta-analytic review of the preventive treatment of recurrences of febrile seizures. The Journal of pediatrics, 1997, Volume: 131, Issue:6 Topics: Anticonvulsants; Chi-Square Distribution; Child; Diazepam; Drug Administration Schedule; Fever; Humans; Odds Ratio; Phenobarbital; Phenytoin; Pyridoxine; Randomized Controlled Trials as Topic; Recurrence; Risk Assessment; Seizures, Febrile; Valproic Acid	1997
Practice parameter: medical treatment of infantile spasms: report of the American Academy of Neurology and the Child Neurology Society. Neurology, 2004, May-25, Volume: 62, Issue:10 Topics: Administration, Oral; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anticonvulsants; Child, Preschool; Drug Therapy, Combination; Evidence-Based Medicine; Female; Follow-Up Studies; Forecasting; Humans; Infant; Male; Nitrazepam; Prospective Studies; Pyridoxine; Randomized Controlled Trials as Topic; Retrospective Studies; Spasms, Infantile; Treatment Outcome; Valproic Acid; Vigabatrin	2004

Trials

2 trial(s) available for valproic acid and pyridoxine

Article	Year
[Outcome of initial treatment with high-dose vitamin B6, valproate sodium or clonazepam in West syndrome]. No to hattatsu = Brain and development, 1996, Volume: 28, Issue:5 Topics: Anticonvulsants; Child; Child, Preschool; Clonazepam; Female; Humans; Infant; Male; Pyridoxine; Spasms, Infantile; Valproic Acid	1996
Long-term follow-up study of vigabatrin in pretreated children with West syndrome. Seizure, 1998, Volume: 7, Issue:4 Topics: Adrenocorticotropic Hormone; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Child, Preschool; Clobazam; Dexamethasone; Drug Therapy, Combination; Electroencephalography; Female; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Infant; Male; Premedication; Prospective Studies; Pyridoxine; Spasms, Infantile; Treatment Outcome; Valproic Acid; Vigabatrin	1998

Article

Year

[Outcome of initial treatment with high-dose vitamin B6, valproate sodium or clonazepam in West syndrome].

No to hattatsu = Brain and development, 1996, Volume: 28, Issue:5

Topics: Anticonvulsants; Child; Child, Preschool; Clonazepam; Female; Humans; Infant; Male; Pyridoxine; Spasms, Infantile; Valproic Acid

1996

Long-term follow-up study of vigabatrin in pretreated children with West syndrome.

Seizure, 1998, Volume: 7, Issue:4

Topics: Adrenocorticotropic Hormone; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Child, Preschool; Clobazam; Dexamethasone; Drug Therapy, Combination; Electroencephalography; Female; gamma-Aminobutyric Acid; Glucocorticoids; Humans; Infant; Male; Premedication; Prospective Studies; Pyridoxine; Spasms, Infantile; Treatment Outcome; Valproic Acid; Vigabatrin

1998

Other Studies

19 other study(ies) available for valproic acid and pyridoxine

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
[Tardive dyskinesia. Synthetic-critical review and case contribution]. L'Ateneo parmense. Acta bio-medica : organo della Societa di medicina e scienze naturali di Parma, 1977, Volume: 48, Issue:1 Topics: Adult; Aged; Baclofen; Dyskinesia, Drug-Induced; Female; Humans; Iatrogenic Disease; Male; Mental Disorders; Methyldopa; Middle Aged; Pyridoxine; Substance Withdrawal Syndrome; Tetrabenazine; Tranquilizing Agents; Valproic Acid	1977
Effects of alterations in the metabolism of gamma-aminobutyrate on convulsant potencies. Epilepsia, 1977, Volume: 18, Issue:4 Topics: 3-Mercaptopropionic Acid; Aminobutyrates; Aminooxyacetic Acid; Animals; Bicuculline; Diacetyl; Drug Synergism; gamma-Aminobutyric Acid; Glycine; Hydrazines; Male; Mice; Pentylenetetrazole; Phenelzine; Picrotoxin; Pyridoxine; Reaction Time; Seizures; Thiones; Valproic Acid	1977
Letter: Sodium valproate in the treatment of intractable childhood epilepsy. Developmental medicine and child neurology, 1975, Volume: 17, Issue:4 Topics: Diazepam; Drug Therapy, Combination; Epilepsy; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Valerates; Valproic Acid	1975
Effect of supplementation with folinic acid, vitamin B6, and vitamin B12 on valproic acid-induced teratogenesis in mice. Fundamental and applied toxicology : official journal of the Society of Toxicology, 1992, Volume: 18, Issue:3 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Animals; Drug Interactions; Embryo, Mammalian; Female; Leucovorin; Mice; Mice, Inbred Strains; Pregnancy; Pyridoxine; Teratogens; Valproic Acid; Vitamin B 12	1992
Changes in the amino acid content of nerve endings (synaptosomes) induced by drugs that alter the metabolism of glutamate and gamma-aminobutyric acid. Journal of neurochemistry, 1984, Volume: 42, Issue:1 Topics: Amino Acids; Aminooxyacetic Acid; Animals; Cyclohexanecarboxylic Acids; gamma-Aminobutyric Acid; Glutamates; Glutamic Acid; Hydrazines; Isoniazid; Male; Mice; Pyridoxal Phosphate; Pyridoxine; Synaptosomes; Valproic Acid	1984
[Biochemical aspects of pathophysiology and treatment of intractable epilepsy in children]. No to hattatsu = Brain and development, 1983, Volume: 15, Issue:2 Topics: Adrenocorticotropic Hormone; Animals; Child; Child, Preschool; Epilepsy; Humans; Indoles; Male; Pyridoxine; Rats; Serotonin; Valproic Acid	1983
A monkey model for status epilepticus: carbamazepine and valproate compared to three standard anticonvulsants. Advances in neurology, 1983, Volume: 34 Topics: Aluminum Hydroxide; Animals; Anticonvulsants; Carbamazepine; Diazepam; Macaca mulatta; Male; Phenobarbital; Phenytoin; Pyridoxine; Status Epilepticus; Valproic Acid	1983
The treatment of infantile spasms by paediatric neurologists in the UK and Ireland. Developmental medicine and child neurology, 1996, Volume: 38, Issue:3 Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Anticonvulsants; gamma-Aminobutyric Acid; Humans; Infant; Infant, Newborn; Ireland; Neurology; Pediatrics; Pituitary Hormones; Prednisone; Pyridoxine; Spasms, Infantile; Surveys and Questionnaires; United Kingdom; Valproic Acid; Vigabatrin; Workforce	1996
Antiepileptic drug treatment of West syndrome. Epilepsia, 1998, Volume: 39 Suppl 5 Topics: Adrenocorticotropic Hormone; Anticonvulsants; Child; Drug Administration Schedule; Drug Therapy, Combination; Drug Utilization; Epilepsy; Follow-Up Studies; Humans; Pyridoxine; Spasms, Infantile; Surveys and Questionnaires; Treatment Outcome; Valproic Acid	1998
Elevated plasma concentrations of homocysteine in antiepileptic drug treatment. Epilepsia, 1999, Volume: 40, Issue:3 Topics: Age Factors; Ambulatory Care; Anticonvulsants; Carbamazepine; Convulsants; Depression, Chemical; Epilepsy; Fasting; Female; Folic Acid; Folic Acid Deficiency; Homocysteine; Humans; Male; Middle Aged; Phenobarbital; Phenytoin; Pyridoxine; Risk Factors; Sex Factors; Valproic Acid; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency	1999
Age-specific N-methyl-D-aspartate-induced seizures: perspectives for the West syndrome model. Epilepsia, 1999, Volume: 40, Issue:10 Topics: Age Factors; Animals; Behavior, Animal; Disease Models, Animal; Electroencephalography; Humans; Hydrocortisone; N-Methylaspartate; Pyridoxine; Rats; Seizures; Spasms, Infantile; Valproic Acid	1999
Current therapy for West syndrome in Japan. Journal of child neurology, 2000, Volume: 15, Issue:6 Topics: Adrenocorticotropic Hormone; Anticonvulsants; Child; Drug Therapy, Combination; Health Care Surveys; Humans; Japan; Pediatrics; Practice Patterns, Physicians'; Pyridoxine; Spasms, Infantile; Surveys and Questionnaires; Valproic Acid	2000
Anti-epileptic drug treatment in children: hyperhomocysteinaemia, B-vitamins and the 677C-->T mutation of the methylenetetrahydrofolate reductase gene. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2000, Volume: 4, Issue:6 Topics: Adolescent; Anticonvulsants; Carbamazepine; Child; Child, Preschool; Folic Acid; Genotype; Homocysteine; Humans; Hyperhomocysteinemia; Infant; Methylenetetrahydrofolate Reductase (NADPH2); Mutation; Oxidoreductases Acting on CH-NH Group Donors; Pyridoxine; Valproic Acid	2000
Drug-induced pertubation of the aminothiol redox-status in patients with epilepsy: improvement by B-vitamins. Epilepsy research, 2008, Volume: 82, Issue:1 Topics: Adult; Anticonvulsants; Carbamazepine; Case-Control Studies; Cysteine; Dipeptides; Drug Evaluation; Epilepsy; Female; Folic Acid; Humans; Hyperhomocysteinemia; Liver; Male; Methionine; Oxidation-Reduction; Phenobarbital; Phenytoin; Primidone; Pyridoxine; Riboflavin; Valproic Acid; Vitamin B Deficiency	2008