valproic acid and propranolol

valproic acid has been researched along with propranolol in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	9 (12.86)	18.7374
1990's	2 (2.86)	18.2507
2000's	23 (32.86)	29.6817
2010's	30 (42.86)	24.3611
2020's	6 (8.57)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Jolivette, LJ; Ward, KW	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Lombardo, F; Obach, RS; Waters, NJ	1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM	1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Glen, RC; Lowe, R; Mitchell, JB	1
Ekins, S; Williams, AJ; Xu, JJ	1
Honda, K; Izumi, T; Miyaji, Y; Nakayama, S; Okazaki, O; Okudaira, N; Shiosakai, K; Sugiyama, D; Suzuki, W; Takakusa, H; Watanabe, A	1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V	1
Barber, J; Dawson, S; Kenna, JG; Paul, N; Stahl, S	1
Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T	1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Chatzopoulou, M; Demopoulos, VJ; Kristl, A; Patsilinakos, A; Prnova, MS; Ragno, R; Stefek, M; Tsantili-Kakoulidou, A; Vallianatou, T; Zakelj, S	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jones, LH; Nadanaciva, S; Rana, P; Will, Y	1
Budziszewska, B; Koczurkiewicz, P; Marona, H; Pańczyk, K; Pękala, E; Piska, K; Pytka, K; Rapacz, A; Starek-Świechowicz, B; Waszkielewicz, AM	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Gourmel, B; Nataf, N; Rossignol, P	1
Lerer, B	1
Hanano, M; Iga, T; Sawada, Y; Sugiyama, Y	1
Emrich, HM; von Zerssen, D	1
Bauman, AW; Hammond, EJ; Karas, BJ; Wilder, BJ	1
Müller, FO; Steyn, JM	1
Emrich, HM; Kissling, W; Möller, HJ; von Zerssen, D; Windorfer, A	1
Cramer, JA; Mattson, RH	1
Kaniecki, RG	1
Chronicle, EP; Mulleners, WM; Palmer, JE; Rolan, P	1
Evers, S; Gerber, WD; Naumann, E; Pothmann, R; Uberall, M	1
De Sarro, A; De Sarro, G; Di Paola, ED; Ferreri, G; Fischer, W	1
Mayer, J; McDiarmid, T; Spry, H; Stanton, RN	1
Mannix, LK	1
Evans, RW; Láinez, MJ; Leira, R; Pascual, J	1
Raskind, MA; Rosin, RA	1
Ashrafi, MR; Mahfelati, F; Shabanian, R; Zamani, GR	1
Dainese, F; Maggioni, F; Mainardi, F; Ruffatti, S; Zanchin, G	1
Kawasaki, A; Purvin, VA; Williams, PE	1
Quimbo, RM; Rupnow, MF; Wertz, DA; Yaldo, AZ	1
Abolfazl, MB; Keyvan, G	1
Bidabadi, E; Mashouf, M	1
Aydin, M; Bozdag, S; Ertugrul, S; Kabakus, N	1
Li, Q; Tan, G; Zhou, J	1
Chronicle, EP; Linde, M; McCrory, DC; Mulleners, WM	1
Charles, A; McGuire, B; Pradhan, AA; Tarash, I; Tipton, AF	1
Ak, S; Atasayar, G; Can, FE; Cecener, G; Egeli, U; Eryilmaz, IE; Karli, N; Taskapilioglu, O; Tezcan, G; Tunca, B; Yildirim, O; Zarifoglu, M	1
Barchukov, VG; Kundashev, UK; Morozov, IS; Salenko, YA; Zurdinov, AZ	1
Golding, AN; Houle, TT; Turner, DP	1
He, A; Li, C; Song, D; Zhang, L	1
Abe, K; Hashimura, M; Iha, HA; Iwai, C; Kato, M; Kawaji, S; Kawakita, K; Kunisawa, N; Ogawa, M; Ohno, Y; Shimizu, S	1
Hayashino, Y; Jackson, JL; Jackson, W; Kuriyama, A; Kuwatsuka, Y; Nickoloff, S; Storch, D; Zhang, ZJ	1
Arvaniti, C; Constantinidis, TS; Fakas, N; Giannouli, E; Kalamatas, T; Kararizou, E; Kouremenos, E; Mitsikostas, DD; Naoumis, D	1
Branch, S; Gaki, E; Morgan, S; Siapkara, A	1
Edem, P; Günay, Ç; Hız-Kurul, AS; Yaşar, E; Yiş, U	1
Akbari, Z; Ardestani, PM; Gholampour, M; Kouhanjani, MF; Nemati, H; Sarvipour, N; Shafie'ei, M; Shekouh, D	1
Ahmadzadeh, S; Bocklud, BE; Corley, SC; Granier, MA; Ingram, EE; Kaye, AD; Neuchat, EE; Shekoohi, S	1
Chen, JJ; Chen, TY; Chen, YW; Hsu, CW; Stubbs, B; Su, KP; Tseng, PT; Tu, YK; Wu, YC; Zeng, BS; Zeng, BY	1

Reviews

14 review(s) available for valproic acid and propranolol

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Alternative therapies for bipolar disorder. The Journal of clinical psychiatry, 1985, Volume: 46, Issue:8 Topics: Ascorbic Acid; Bipolar Disorder; Bupropion; Carbamazepine; Choline; Clonazepam; Clonidine; Clorgyline; Demeclocycline; Fenfluramine; Humans; Methylene Blue; Phosphatidylcholines; Physostigmine; Propiophenones; Propranolol; Spironolactone; Thyroxine; Tryptophan; Valproic Acid	1985
Prediction of the disposition of nine weakly acidic and six weakly basic drugs in humans from pharmacokinetic parameters in rats. Journal of pharmacokinetics and biopharmaceutics, 1985, Volume: 13, Issue:5 Topics: Animals; Antipyrine; Barbiturates; Biological Availability; Chlorpromazine; Diazepam; Drug Evaluation; Female; Half-Life; Humans; Kinetics; Male; Metabolic Clearance Rate; Pentazocine; Pharmaceutical Preparations; Phenylbutazone; Phenytoin; Propranolol; Quinidine; Rats; Species Specificity; Tissue Distribution; Tolbutamide; Valproic Acid; Warfarin	1985
[Treatment of idiopathic headache in childhood - recommendations of the German Migraine and Headache Society (DMKG)]. Schmerz (Berlin, Germany), 2002, Volume: 16, Issue:1 Topics: Acetaminophen; Adrenergic beta-Antagonists; Age Factors; Analgesics, Non-Narcotic; Biofeedback, Psychology; Child; Flunarizine; GABA Agents; Headache; Humans; Ibuprofen; Metoprolol; Migraine Disorders; Practice Guidelines as Topic; Propranolol; Relaxation Therapy; Serotonin Receptor Agonists; Sumatriptan; Tension-Type Headache; Valproic Acid; Vasodilator Agents	2002
Clinical inquiries. What medication best prevents migraine in children? The Journal of family practice, 2003, Volume: 52, Issue:10 Topics: Amitriptyline; Child; Evidence-Based Medicine; Humans; Migraine Disorders; Propranolol; Valproic Acid	2003
Clinical advances in the preventive treatment of migraine. Acta neurologica Taiwanica, 2004, Volume: 13, Issue:4 Topics: Amitriptyline; Fructose; Humans; Migraine Disorders; Propranolol; Topiramate; Valproic Acid	2004
Valproate (valproic acid or sodium valproate or a combination of the two) for the prophylaxis of episodic migraine in adults. The Cochrane database of systematic reviews, 2013, Jun-24, Issue:6 Topics: Adult; Anticonvulsants; Flunarizine; Fructose; Humans; Migraine Disorders; Propranolol; Randomized Controlled Trials as Topic; Topiramate; Valproic Acid	2013
Prevention of migraine attacks. First-choice treatments. Prescrire international, 2015, Volume: 24, Issue:157 Topics: Adrenergic beta-Antagonists; Amitriptyline; Analgesics; Anticonvulsants; Antidepressive Agents, Tricyclic; Female; Humans; Migraine Disorders; Pregnancy; Pregnancy Complications; Propranolol; Risk Factors; Risk Reduction Behavior; Treatment Outcome; Valproic Acid	2015
Unveiling the relative efficacy, safety and tolerability of prophylactic medications for migraine: pairwise and network-meta analysis. The journal of headache and pain, 2017, Volume: 18, Issue:1 Topics: Adult; Amines; Amitriptyline; Anticonvulsants; Cyclohexanecarboxylic Acids; Dizziness; Female; Fructose; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Migraine Disorders; Nausea; Pre-Exposure Prophylaxis; Propranolol; Randomized Controlled Trials as Topic; Topiramate; Treatment Outcome; Valproic Acid	2017
Beta-blockers for the prevention of headache in adults, a systematic review and meta-analysis. PloS one, 2019, Volume: 14, Issue:3 Topics: Adrenergic beta-Antagonists; Adult; Clinical Trials as Topic; Female; Humans; Male; Migraine Disorders; Propranolol; Tension-Type Headache; Topiramate; Valproic Acid	2019
Application of cinnarizine in migraine prevention: A systematic review and meta-analysis. Pain practice : the official journal of World Institute of Pain, 2022, Volume: 22, Issue:8 Topics: Activities of Daily Living; Cinnarizine; Humans; Migraine Disorders; Propranolol; Quality of Life; Valproic Acid	2022
Non-CGRP Antagonist/Non-Triptan Options for Migraine Disease Treatment: Clinical Considerations. Current pain and headache reports, 2023, Volume: 27, Issue:10 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents; Calcium Channel Blockers; Drug-Related Side Effects and Adverse Reactions; Humans; Migraine Disorders; Propranolol; Serotonin 5-HT1 Receptor Agonists; Topiramate; Tryptamines; Valproic Acid	2023
Network Meta-analysis of Different Treatments for Vestibular Migraine. CNS drugs, 2023, Volume: 37, Issue:9 Topics: Adult; Female; Humans; Male; Migraine Disorders; Network Meta-Analysis; Propranolol; Valproic Acid; Venlafaxine Hydrochloride	2023

Trials

7 trial(s) available for valproic acid and propranolol

Article	Year
Treatment of valproate tremors. Neurology, 1983, Volume: 33, Issue:10 Topics: Amantadine; Cyproheptadine; Diphenhydramine; Humans; Propranolol; Tremor; Valproic Acid	1983
Effect of sodium valproate on mania. The GABA-hypothesis of affective disorders. Archiv fur Psychiatrie und Nervenkrankheiten, 1980, Volume: 229, Issue:1 Topics: Adolescent; Adult; Affective Disorders, Psychotic; Alcohol Withdrawal Delirium; Bipolar Disorder; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; gamma-Aminobutyric Acid; Humans; Lithium; Male; Middle Aged; Placebos; Propranolol; Valproic Acid	1980
A comparison of divalproex with propranolol and placebo for the prophylaxis of migraine without aura. Archives of neurology, 1997, Volume: 54, Issue:9 Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Cross-Over Studies; Female; GABA Agents; Humans; Male; Middle Aged; Migraine Disorders; Placebos; Propranolol; Sensation Disorders; Single-Blind Method; Treatment Outcome; Valproic Acid	1997
Sodium Valproate versus Propranolol in paediatric migraine prophylaxis. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society, 2005, Volume: 9, Issue:5 Topics: Adolescent; Adrenergic beta-Antagonists; Anticonvulsants; Child; Child, Preschool; Humans; Incidence; Migraine Disorders; Propranolol; Severity of Illness Index; Time Factors; Treatment Outcome; Valproic Acid	2005
Weight variations in the prophylactic therapy of primary headaches: 6-month follow-up. The journal of headache and pain, 2005, Volume: 6, Issue:4 Topics: Adrenergic beta-Antagonists; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Anticonvulsants; Atenolol; Cyclohexanecarboxylic Acids; Female; Follow-Up Studies; Gabapentin; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Migraine with Aura; Migraine without Aura; Pizotyline; Propranolol; Tension-Type Headache; Valproic Acid; Vasodilator Agents; Verapamil; Weight Gain	2005
Comparison of treatment effect of sodium valproate, propranolol and tricyclic antidepressants in migraine. Pakistan journal of biological sciences : PJBS, 2009, Aug-01, Volume: 12, Issue:15 Topics: Anticonvulsants; Antidepressive Agents, Tricyclic; Humans; Migraine Disorders; Propranolol; Treatment Outcome; Valproic Acid; Vasodilator Agents	2009
A randomized trial of propranolol versus sodium valproate for the prophylaxis of migraine in pediatric patients. Paediatric drugs, 2010, Aug-01, Volume: 12, Issue:4 Topics: Adolescent; Child; Child, Preschool; Humans; Migraine Disorders; Propranolol; Time Factors; Valproic Acid	2010

Other Studies

49 other study(ies) available for valproic acid and propranolol

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. Journal of pharmaceutical sciences, 2005, Volume: 94, Issue:7 Topics: Algorithms; Animals; Dogs; Haplorhini; Humans; Pharmaceutical Preparations; Pharmacokinetics; Rats; Species Specificity; Tissue Distribution	2005
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11 Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship	2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19 Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Predicting phospholipidosis using machine learning. Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5 Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:7 Topics: Glutathione; Pharmacology; Sulfur Radioisotopes	2011
FDA-approved drug labeling for the study of drug-induced liver injury. Drug discovery today, 2011, Volume: 16, Issue:15-16 Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration	2011
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Cholestasis; Drug-Related Side Effects and Adverse Reactions; Humans; Insecta; Rats; Risk Factors	2012
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. Journal of medicinal chemistry, 2012, Jan-12, Volume: 55, Issue:1 Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse Reactions; Fibroblasts; Lipidoses; Lysosomal Storage Diseases; Models, Molecular; Pharmaceutical Preparations; Phospholipids; Structure-Activity Relationship; Thermodynamics	2012
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10 Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection	2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation. Bioorganic & medicinal chemistry, 2014, Apr-01, Volume: 22, Issue:7 Topics: Aldehyde Reductase; Animals; Cell Membrane Permeability; Dose-Response Relationship, Drug; Enzyme Inhibitors; Jejunum; Lenses; Male; Models, Molecular; Molecular Structure; Phenols; Pyrroles; Rats; Rats, Wistar; Sorbitol; Structure-Activity Relationship	2014
Development of a cell viability assay to assess drug metabolite structure-toxicity relationships. Bioorganic & medicinal chemistry letters, 2016, 08-15, Volume: 26, Issue:16 Topics: Adenosine Triphosphate; Benzbromarone; Cell Line; Cell Survival; Chromans; Cytochrome P-450 CYP2C9; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Humans; Pharmaceutical Preparations; Thiazolidinediones; Troglitazone	2016
Design, synthesis and anticonvulsant-analgesic activity of new MedChemComm, 2017, Jan-01, Volume: 8, Issue:1 Topics:	2017
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Pharmacological actions on hypoxic increase of rat brain cortex extracellular K+ ion. Pharmacological research communications, 1978, Volume: 10, Issue:7 Topics: Animals; Cerebral Cortex; Extracellular Space; Hypoxia; Male; Phenytoin; Potassium; Propranolol; Pyrithioxin; Rats; Stereoisomerism; Valproic Acid; Vincamine	1978
New drugs for mania? The British journal of psychiatry : the journal of mental science, 1983, Volume: 142 Topics: Affective Disorders, Psychotic; Bipolar Disorder; Humans; Propranolol; Psychotic Disorders; Valproic Acid	1983
Comparative effects of two commercially available blood collection tubes on plasma concentrations of drugs. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Jan-26, Volume: 57, Issue:4 Topics: Acebutolol; Blood Specimen Collection; Carbamazepine; Diazepam; Digoxin; Ethosuximide; Humans; Nordazepam; Penbutolol; Pharmaceutical Preparations; Propranolol; Quinidine; Salicylates; Time Factors; Valproic Acid; Warfarin	1980
Tremor due to sodium valproate. Neurology, 1981, Volume: 31, Issue:1 Topics: Humans; Propranolol; Tremor; Valproic Acid	1981
New "triptans" and other drugs for migraine. The Medical letter on drugs and therapeutics, 1998, Oct-09, Volume: 40, Issue:1037 Topics: Adrenergic beta-Antagonists; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Tricyclic; Calcium Channel Blockers; Dihydroergotamine; Drug Interactions; Ergotamine; Humans; Indoles; Methysergide; Migraine Disorders; Naproxen; Oxazoles; Oxazolidinones; Piperidines; Propranolol; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Sumatriptan; Time Factors; Timolol; Triazoles; Tryptamines; Valproic Acid; Vasoconstrictor Agents	1998
Cortical hyperexcitability is cortical under-inhibition: evidence from a novel functional test of migraine patients. Cephalalgia : an international journal of headache, 2000, Volume: 20, Issue:6 Topics: Adult; Aged; Analgesics; Cortical Spreading Depression; Female; GABA-A Receptor Agonists; gamma-Aminobutyric Acid; Humans; Male; Methysergide; Middle Aged; Migraine Disorders; Migraine with Aura; Perceptual Masking; Photic Stimulation; Pizotyline; Propranolol; Valproic Acid; Visual Cortex	2000
Influence of some beta-adrenoceptor antagonists on the anticonvulsant potency of antiepileptic drugs against audiogenic seizures in DBA/2 mice. European journal of pharmacology, 2002, May-10, Volume: 442, Issue:3 Topics: Acoustic Stimulation; Adrenergic beta-Antagonists; Animals; Anticonvulsants; Atenolol; Body Temperature; Carbamazepine; Epilepsy, Reflex; Female; Lamotrigine; Male; Metoprolol; Mice; Mice, Inbred DBA; Motor Activity; Phenobarbital; Propanolamines; Propranolol; Stereoisomerism; Triazines; Valproic Acid	2002
Bending the rule of monotherapy for migraine prevention? Headache, 2005, Volume: 45, Issue:6 Topics: Adrenergic beta-Antagonists; Adult; Amitriptyline; Drug Therapy, Combination; Female; Humans; Migraine Disorders; Propranolol; Valproic Acid	2005
Gonadotrophin-releasing hormone agonist treatment of aggression in Alzheimer's disease: a case report. International psychogeriatrics, 2005, Volume: 17, Issue:2 Topics: Aged; Aggression; Alzheimer Disease; Amines; Antipsychotic Agents; Benzodiazepines; Cyclohexanecarboxylic Acids; Dibenzothiazepines; Gabapentin; gamma-Aminobutyric Acid; Gonadotropin-Releasing Hormone; Goserelin; Humans; Male; Olanzapine; Propranolol; Quetiapine Fumarate; Risperidone; Testosterone; Trazodone; Treatment Outcome; Valproic Acid	2005
Pharmacological prevention of migraine: to be considered case by case. Prescrire international, 2006, Volume: 15, Issue:85 Topics: Adrenergic beta-Antagonists; Amitriptyline; Anticonvulsants; Antidepressive Agents; Cost-Benefit Analysis; Flunarizine; France; Humans; Methysergide; Migraine Disorders; Pizotyline; Propranolol; Serotonin Antagonists; United Kingdom; Valproic Acid	2006
Superior oblique myokymia: efficacy of medical treatment. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus, 2007, Volume: 11, Issue:3 Topics: Adolescent; Adult; Aged; Anticonvulsants; Carbamazepine; Diplopia; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Male; Middle Aged; Optical Illusions; Phenytoin; Propranolol; Retrospective Studies; Treatment Outcome; Trochlear Nerve Diseases; Valproic Acid	2007
Psychopharmacology news. New side effects of agents. Journal of child and adolescent psychopharmacology, 2007, Volume: 17, Issue:3 Topics: Benzodiazepines; Bupropion; Female; Humans; Olanzapine; Pregnancy; Propranolol; Psychotropic Drugs; Valproic Acid	2007
Persistence with migraine prophylactic treatment and acute migraine medication utilization in the managed care setting. Clinical therapeutics, 2008, Volume: 30, Issue:12 Topics: Adult; Age Factors; Amitriptyline; Cohort Studies; Databases, Factual; Dose-Response Relationship, Drug; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization Review; Female; Fructose; Humans; Kaplan-Meier Estimate; Male; Managed Care Programs; Medication Adherence; Middle Aged; Migraine Disorders; Proportional Hazards Models; Propranolol; Retrospective Studies; Sex Factors; Time Factors; Timolol; Topiramate; Valproic Acid	2008
Profile of children with migraine. Indian journal of pediatrics, 2010, Volume: 77, Issue:11 Topics: Adolescent; Anticonvulsants; Child; Child, Preschool; Female; Flunarizine; Fructose; Humans; Male; Migraine Disorders; Prevalence; Propranolol; Risk Factors; Topiramate; Turkey; Valproic Acid; Vasodilator Agents	2010
Basilar-type migraine with coma: case reports and literature review. Pain medicine (Malden, Mass.), 2011, Volume: 12, Issue:4 Topics: Adolescent; Anticonvulsants; Antihypertensive Agents; Asian People; Coma; Female; Humans; Male; Migraine with Aura; Propranolol; Treatment Outcome; Valproic Acid	2011
Drugs to prevent migraines are underused. Consumer reports, 2012, Volume: 77, Issue:7 Topics: Adrenergic beta-Antagonists; Anticonvulsants; Fructose; Humans; Migraine Disorders; Preventive Health Services; Propranolol; Timolol; Treatment Outcome; United States; Valproic Acid	2012
The effects of acute and preventive migraine therapies in a mouse model of chronic migraine. Cephalalgia : an international journal of headache, 2016, Volume: 36, Issue:11 Topics: Acute Disease; Amiloride; Animals; Anticonvulsants; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Humans; Male; Mice; Migraine Disorders; Nitroglycerin; Pain Measurement; Propranolol; Serotonin 5-HT1 Receptor Agonists; Species Specificity; Sumatriptan; Treatment Outcome; Valproic Acid; Vasodilator Agents	2016
Association of MDR1, CYP2D6, and CYP2C19 gene polymorphisms with prophylactic migraine treatment response. Journal of the neurological sciences, 2016, Jul-15, Volume: 366 Topics: Adult; Amitriptyline; ATP Binding Cassette Transporter, Subfamily B; Central Nervous System Agents; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Drug Resistance; Female; Fructose; Gene Frequency; Genetic Association Studies; Humans; Male; Migraine Disorders; Polymorphism, Genetic; Propranolol; Risk Factors; Topiramate; Treatment Outcome; Valproic Acid	2016
[EFFECT OF MEDIATOR-TYPE DRUGS ON HUMAN PSYCHOPHYSIOLOGICAL STATUS DURING MODEL OPERATOR ACTIVITY]. Eksperimental'naia i klinicheskaia farmakologiia, 2016, Volume: 79, Issue:2 Topics: Adult; Anabasine; Attention; Belladonna Alkaloids; Benzodiazepines; Central Nervous System Stimulants; Dioxanes; Double-Blind Method; Haloperidol; Humans; Isoproterenol; Male; Propranolol; Psychophysiology; Sydnones; Task Performance and Analysis; Tranquilizing Agents; Valproic Acid; Yohimbine	2016
Using a graphical risk tool to examine willingness to take migraine prophylactic medications. Pain, 2016, Volume: 157, Issue:10 Topics: Amines; Analgesics; Antidepressive Agents; Antihypertensive Agents; Cross-Sectional Studies; Cyclohexanecarboxylic Acids; Female; Gabapentin; gamma-Aminobutyric Acid; Headache; Humans; Longitudinal Studies; Male; Migraine Disorders; Pain Measurement; Pre-Exposure Prophylaxis; Propranolol; Retrospective Studies; Surveys and Questionnaires; Valproic Acid; Venlafaxine Hydrochloride	2016
Pharmacological characterization of nicotine-induced tremor: Responses to anti-tremor and anti-epileptic agents. Journal of pharmacological sciences, 2018, Volume: 137, Issue:2 Topics: Animals; Anticonvulsants; Antiparkinson Agents; Benzeneacetamides; Calcium Channel Blockers; Carbamazepine; Diazepam; Disease Models, Animal; Essential Tremor; Ethosuximide; Male; Mice, Inbred Strains; Nicotine; Phenobarbital; Propranolol; Pyridines; Valproic Acid	2018
Consensus of the Hellenic Headache Society on the diagnosis and treatment of migraine. The journal of headache and pain, 2019, Dec-13, Volume: 20, Issue:1 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal; Botulinum Toxins, Type A; Consensus; Greece; Humans; Migraine Disorders; Propranolol; Societies, Medical; Treatment Outcome; Tryptamines; Valproic Acid	2019
Sodium valproate in paediatric migraine. Cephalalgia : an international journal of headache, 2020, Volume: 40, Issue:7 Topics: Child; Cinnarizine; Double-Blind Method; Humans; Migraine Disorders; Propranolol; Valproic Acid	2020
Recurrent painful ophthalmoplegic neuropathy: a report of two new pediatric cases. The Turkish journal of pediatrics, 2022, Volume: 64, Issue:3 Topics: Child; Child, Preschool; Female; Headache; Humans; Magnetic Resonance Imaging; Ophthalmoplegia; Ophthalmoplegic Migraine; Pain; Peripheral Nervous System Diseases; Propranolol; Tolosa-Hunt Syndrome; Valproic Acid	2022